taenia solium

Summary

Summary: Species of tapeworm in the genus TAENIA, that infects swine. It is acquired by humans through the ingestion of cured or undercooked pork.

Top Publications

  1. Asnis D, Kazakov J, Toronjadze T, Bern C, Garcia H, McAuliffe I, et al. Neurocysticercosis in the infant of a pregnant mother with a tapeworm. Am J Trop Med Hyg. 2009;81:449-51 pubmed
    Taeniasis occurs after ingestion of undercooked pork infected with cysticerci. Most Taenia solium infections are mild; proglottids are rarely noticed in the feces. Cysticercosis develops with ingestion of eggs from a tapeworm carrier...
  2. Rajshekhar V. Surgical management of neurocysticercosis. Int J Surg. 2010;8:100-4 pubmed publisher
    Neurocysticercosis (NCC) is caused by the larval form of the pork tapeworm Taenia solium and is the commonest parasitic infestation of the central nervous system. NCC is usually managed medically but in some instances surgery is required...
  3. Deckers N, Dorny P. Immunodiagnosis of Taenia solium taeniosis/cysticercosis. Trends Parasitol. 2010;26:137-44 pubmed publisher
    Neurocysticercosis, the infection of the central nervous system by larvae of Taenia solium, is a major cause of epilepsy in developing countries...
  4. Lightowlers M. Vaccination for the prevention of cysticercosis. Dev Biol (Basel). 2004;119:361-8 pubmed
    ..The most important species is Taenia solium, which infects pigs as the natural animal intermediate host but also may infect humans as intermediate hosts, ..
  5. Chavarria A, Fleury A, Garcia E, Márquez C, Fragoso G, Sciutto E. Relationship between the clinical heterogeneity of neurocysticercosis and the immune-inflammatory profiles. Clin Immunol. 2005;116:271-8 pubmed
    Human neurocysticercosis is caused by the establishment of Taenia solium cysticerci in the central nervous system. Neurocysticercosis may be asymptomatic or manifested by non-specific mild to severe neurological symptoms...
  6. Illescas O, Carrero J, Bobes R, Flisser A, Rosas G, Laclette J. Molecular characterization, functional expression, tissue localization and protective potential of a Taenia solium fatty acid-binding protein. Mol Biochem Parasitol. 2012;186:117-25 pubmed publisher
    ..identification, characterization, recombinant expression, tissue localization and protective potential of a Taenia solium FABP (TsFABP1)...
  7. Lescano A, Garcia H, Gilman R, Gavidia C, Tsang V, Rodriguez S, et al. Taenia solium cysticercosis hotspots surrounding tapeworm carriers: clustering on human seroprevalence but not on seizures. PLoS Negl Trop Dis. 2009;3:e371 pubmed publisher
    ..We assessed the clustering patterns of Taenia solium human cysticercosis seropositivity and seizures around tapeworm carriers in seven rural communities in Peru...
  8. Assana E, Kyngdon C, Gauci C, Geerts S, Dorny P, De Deken R, et al. Elimination of Taenia solium transmission to pigs in a field trial of the TSOL18 vaccine in Cameroon. Int J Parasitol. 2010;40:515-9 pubmed publisher
    ..Necropsies were undertaken when the pigs were approximately 12 months of age. Viable Taenia solium cysticerci were identified in 20 control pigs (prevalence 19...
  9. Sato M, Sako Y, Nakao M, Wandra T, Nakaya K, Yanagida T, et al. A possible nuclear DNA marker to differentiate the two geographic genotypes of Taenia solium tapeworms. Parasitol Int. 2011;60:108-10 pubmed publisher
    Cysticercosis caused by infection with embryonated eggs of the pork tapeworm Taenia solium is an important cause of neurological disease worldwide...

More Information

Publications106 found, 100 shown here

  1. Piña R, Gutiérrez A, Gilman R, Rueda D, Sifuentes C, Flores M, et al. A dot-ELISA using a partially purified cathepsin-L-like protein fraction from Taenia solium cysticerci, for the diagnosis of human neurocysticercosis. Ann Trop Med Parasitol. 2011;105:311-8 pubmed publisher
    Human neurocysticercosis (NCC), caused by the cestode Taenia solium, is responsible for a significant amount of neurological morbidity and epilepsy in developing countries...
  2. Kyngdon C, Gauci C, Rolfe R, Velásquez Guzmán J, Farfán Salazar M, Verástegui Pimentel M, et al. In vitro oncosphere-killing assays to determine immunity to the larvae of Taenia pisiformis, Taenia ovis, Taenia saginata, and Taenia solium. J Parasitol. 2006;92:273-81 pubmed
    ..of host-protective serum antibodies against Taenia pisiformis, Taenia ovis, Taenia saginata, and Taenia solium in rabbits, sheep, cattle, and pigs, respectively. Activated oncospheres of T. pisiformis, T. ovis, T...
  3. Assana E, Kanobana K, Tume C, Zoli P, Nguekam -, Geerts S, et al. Isolation of a 14 kDa antigen from Taenia solium cyst fluid by HPLC and its evaluation in enzyme linked immunosorbent assay for diagnosis of porcine cysticercosis. Res Vet Sci. 2007;82:370-6 pubmed
    A fraction with a major band of 14kDa was obtained from crude cyst fluid of Taenia solium cysticerci by 2-step chromatography...
  4. Mamkin I, Sood N, Ramanan S. Taenia solium neurocysticercosis. N Engl J Med. 2007;357:1666-7 pubmed
  5. Guezala M, Rodriguez S, Zamora H, Garcia H, Gonzalez A, Tembo A, et al. Development of a species-specific coproantigen ELISA for human Taenia solium taeniasis. Am J Trop Med Hyg. 2009;81:433-7 pubmed
    b>Taenia solium causes human neurocysticercosis and is endemic in underdeveloped countries where backyard pig keeping is common. Microscopic fecal diagnostic methods for human T...
  6. Gauci C, Jayashi C, Gonzalez A, Lackenby J, Lightowlers M. Protection of pigs against Taenia solium cysticercosis by immunization with novel recombinant antigens. Vaccine. 2012;30:3824-8 pubmed publisher
    Recombinant antigens from the oncosphere stage of the parasite Taenia solium were expressed in Escherichia coli...
  7. Fujita M, Mahanty S, Zoghbi S, Ferraris Araneta M, Hong J, Pike V, et al. PET reveals inflammation around calcified Taenia solium granulomas with perilesional edema. PLoS ONE. 2013;8:e74052 pubmed publisher
    ..Novel anti-inflammatory measures may be useful in the prevention or treatment of seizures in this population. ..
  8. Ferrer E, Gonzalez L, Foster Cuevas M, Cortéz M, Dávila I, Rodriguez M, et al. Taenia solium: characterization of a small heat shock protein (Tsol-sHSP35.6) and its possible relevance to the diagnosis and pathogenesis of neurocysticercosis. Exp Parasitol. 2005;110:1-11 pubmed
    ..6, has been isolated by antibody screening of a Taenia solium c-DNA library...
  9. Gauci C, Ito A, Lightowlers M. Conservation of the vaccine antigen gene, TSOL18, among genetically variant isolates of Taenia solium. Mol Biochem Parasitol. 2006;146:101-4 pubmed
  10. Mandal J, Singhi P, Khandelwal N, Malla N. Evaluation of ELISA and dot blots for the serodiagnosis of neurocysticercosis, in children found to have single or multiple enhancing lesions in computerized tomographic scans of the brain. Ann Trop Med Parasitol. 2006;100:39-48 pubmed
    ..the performances of an ELISA and dot-blot assay, for the detection of antibodies against antigens from larval Taenia solium, were investigated and compared, using sera, from children aged 5-12 years, that were diluted to at least 1:..
  11. Arruda G, da Silva A, Quagliato E, Maretti M, Rossi C. Evaluation of Taenia solium and Taenia crassiceps cysticercal antigens for the serodiagnosis of neurocysticercosis. Trop Med Int Health. 2005;10:1005-12 pubmed
    We evaluated the usefulness of seven cysticercal antigen extracts, four from Taenia solium cysticerci (whole parasite-TsoW, membrane-TsoMe, vesicular fluid-TsoVF and scolex-TsoSc) and three from T...
  12. Willingham A, Engels D. Control of Taenia solium cysticercosis/taeniosis. Adv Parasitol. 2006;61:509-66 pubmed
    ..Caused by the pork tapeworm, Taenia solium, this zoonotic disease forms larval cysts in humans and pigs that can lead to epilepsy and death in humans, ..
  13. Sudewi A, Wandra T, Artha A, Nkouawa A, Ito A. Taenia solium cysticercosis in Bali, Indonesia: serology and mtDNA analysis. Trans R Soc Trop Med Hyg. 2008;102:96-8 pubmed
    An active Taenia solium cysticercosis case in Bali, Indonesia, was followed-up by serology and computed tomography...
  14. Avila G, Aguilar L, Romero Valdovinos M, Garcia Vazquez F, Flisser A. Cytokine response in the intestinal mucosa of hamsters infected with Taenia solium. Ann N Y Acad Sci. 2008;1149:170-3 pubmed publisher
    b>Taenia solium grows in experimentally infected hamsters. An inflammatory reaction in the intestinal mucosa surrounding the scolex of the worms is produced...
  15. Flisser A. Where are the tapeworms?. Parasitol Int. 2006;55 Suppl:S117-20 pubmed
    ..The results and comments of the authors that have searched for Taenia solium, either to define the local prevalence in different countries of Latin America, to assess the efficacy of ..
  16. Aguilar Díaz H, Bobes R, Carrero J, Camacho Carranza R, Cervantes C, Cevallos M, et al. The genome project of Taenia solium. Parasitol Int. 2006;55 Suppl:S127-30 pubmed
    ..of key laboratories at the National Autonomous University of Mexico to carry out a genomic project for Taenia solium. This project will provide powerful resources for the study of taeniasis/cysticercosis, and, in conjunction ..
  17. Morales Montor J, Escobedo G, Vargas Villavicencio J, Larralde C. The neuroimmunoendocrine network in the complex host-parasite relationship during murine cysticercosis. Curr Top Med Chem. 2008;8:400-7 pubmed
    ..Such complexity may also help to explain the often conflicting results, observed between infections with respect to the role of the host sex, and hints to other avenues of research and strategies for their treatment and control. ..
  18. Kanobana K, Praet N, Kabwe C, Dorny P, Lukanu P, Madinga J, et al. High prevalence of Taenia solium cysticerosis in a village community of Bas-Congo, Democratic Republic of Congo. Int J Parasitol. 2011;41:1015-8 pubmed publisher
    Cysticercosis results from tissue infection with the larval stage of the pig tapeworm Taenia solium. Infection of the brain may cause neurocysticercosis, the most frequent cause of acquired epilepsy in developing countries...
  19. Ito A, Li T, Chen X, Long C, Yanagida T, Nakao M, et al. Mini review on chemotherapy of taeniasis and cysticercosis due to Taenia solium in Asia, and a case report with 20 tapeworms in China. Trop Biomed. 2013;30:164-73 pubmed
    A 43-year-old Tibetan woman living in northwest Sichuan, China, confirmed to be a taeniasis carrier of Taenia solium was treated with pumpkin seeds combined with Areca nut extract in October 2009...
  20. Ooi W, Wijemanne S, Thomas C, Quezado M, Brown C, Nash T. Short report: A calcified Taenia solium granuloma associated with recurrent perilesional edema causing refractory seizures: histopathological features. Am J Trop Med Hyg. 2011;85:460-3 pubmed publisher
    We describe the first detailed histological description of an excised calcified Taenia solium granuloma from a patient who developed recurrent seizures associated with perilesional edema surrounding a calcified cysticercus (PEC)...
  21. Salazar Anton F, Tellez A, Lindh J. Evaluation of an immunodot blot technique for the detection of antibodies against Taenia solium larval antigens. Parasitol Res. 2012;110:2187-91 pubmed publisher
    ..tests represent an important tool for diagnosis of cysticercosis, the disease caused by cysticerci of Taenia solium. Accurate diagnosis of neurocysticercosis (NCC) requires costly neuroimaging techniques (magnetic resonance ..
  22. Phiri I, Dorny P, Gabriel S, Willingham A, Sikasunge C, Siziya S, et al. Assessment of routine inspection methods for porcine cysticercosis in Zambian village pigs. J Helminthol. 2006;80:69-72 pubmed
    ..While the specificity of tongue palpation and meat inspection was 100%, these tests failed to detect the infection in 83.9% and 61.3% of infected pigs, respectively. ..
  23. Harrington A, Creutzfeldt C, Sengupta D, Hoogestraat D, Zunt J, Cookson B. Diagnosis of neurocysticercosis by detection of Taenia solium DNA using a global DNA screening platform. Clin Infect Dis. 2009;48:86-90 pubmed publisher
    Neurocysticercosis is caused by Taenia solium infection of the brain...
  24. León Cabrera S, Cruz Rivera M, Mendlovic F, Avila Ramírez G, Carrero J, Laclette J, et al. Standardization of an experimental model of human taeniosis for oral vaccination. Methods. 2009;49:346-50 pubmed publisher
    Neurocysticercosis in humans is caused by the tapeworm Taenia solium and generates substantial morbidity in Latin America, Africa and Asia.The life cycle of T...
  25. Sahu P, Parija S, Jayachandran S. Antibody specific to 43kDa excretory-secretory antigenic peptide of Taenia solium metacestode as a potential diagnostic marker in human neurocysticercosis. Acta Trop. 2010;115:257-61 pubmed publisher
    ..The objective of the present study was to characterize the ES antigens collected from in vitro culture of Taenia solium metacestode larvae, and to identify specific ES peptides as diagnostic markers. Three ES peptides viz...
  26. Swastika K, Dewiyani C, Yanagida T, Sako Y, Sudarmaja M, Sutisna P, et al. An ocular cysticercosis in Bali, Indonesia caused by Taenia solium Asian genotype. Parasitol Int. 2012;61:378-80 pubmed publisher
    ..However, mitochondrial DNA analysis using a piece of histopathological specimen revealed it a cysticercus of Taenia solium Asian genotype. Serology by immunoblot and ELISA highly specific to cysticercosis was negative.
  27. Nash T, Pretell E, Lescano A, Bustos J, Gilman R, Gonzalez A, et al. Perilesional brain oedema and seizure activity in patients with calcified neurocysticercosis: a prospective cohort and nested case-control study. Lancet Neurol. 2008;7:1099-105 pubmed publisher
    Cysticercosis due to Taenia solium is a cause of adult-acquired seizures and epilepsy even in patients with only calcified larval cysts...
  28. Deckers N, Saerens D, Kanobana K, Conrath K, Victor B, Wernery U, et al. Nanobodies, a promising tool for species-specific diagnosis of Taenia solium cysticercosis. Int J Parasitol. 2009;39:625-33 pubmed publisher
    b>Taenia solium cysticercosis is a major helminth zoonosis in developing countries. Pigs are the intermediate hosts mediating transmission of infection. Specific assays to diagnose living cysts in pigs are lacking...
  29. Alexander A, Prabhakaran V, Rajshekhar V, Muliyil J, Dorny P. Long-term clinical evaluation of asymptomatic subjects positive for circulating Taenia solium antigens. Trans R Soc Trop Med Hyg. 2010;104:809-10 pubmed publisher
    ..We conclude that asymptomatic individuals with circulating cysticercal antigens have a low risk of developing symptomatic cysticercosis within four to five years. ..
  30. Yamasaki H, Nakao M, Sako Y, Nakaya K, Ito A. Molecular identification of Taenia solium cysticercus genotype in the histopathological specimens. Southeast Asian J Trop Med Public Health. 2005;36 Suppl 4:131-4 pubmed
    ..solium Asian genotype. When infection with T. solium is not confirmed by histopathological examination, molecular diagnosis will be more useful for definitive diagnosis...
  31. Mayta H, Hancock K, Levine M, Gilman R, Farfán M, Verastegui M, et al. Characterization of a novel Taenia solium oncosphere antigen. Mol Biochem Parasitol. 2007;156:154-61 pubmed
    Infections due to Taenia solium in humans (taeniasis/cysticercosis) remain a complex health problem, particularly in developing countries...
  32. Furrows S, McCroddan J, Bligh W, Chiodini P. Lack of specificity of a single positive 50-kDa band in the electroimmunotransfer blot (EITB) assay for cysticercosis. Clin Microbiol Infect. 2006;12:459-62 pubmed
    ..is a sensitive and specific assay, which uses six glycoprotein antigens on a strip to detect antibodies to Taenia solium cysticerci...
  33. Sikasunge C, Phiri I, Phiri A, Dorny P, Siziya S, Willingham A. Risk factors associated with porcine cysticercosis in selected districts of Eastern and Southern provinces of Zambia. Vet Parasitol. 2007;143:59-66 pubmed
    To determine the risk factors associated with Taenia solium transmission in humans and pigs in the rural areas of Eastern and Southern provinces of Zambia, a questionnaire was administered in 788 households from 155 villages...
  34. Garrido G, de Aluja A, Casas F. Early stages of development of the Taenia solium metacestode in pigs. J Parasitol. 2007;93:238-41 pubmed
    In order to identify the early stages of Taenia solium metacestodes, 12 pigs were each fed 100,000 viable eggs and later killed and necropsied at different times after infection...
  35. Arana Y, Verastegui M, Tuero I, Grandjean L, Garcia H, Gilman R. Characterization of the carbohydrate components of Taenia solium oncosphere proteins and their role in the antigenicity. Parasitol Res. 2013;112:3569-78 pubmed publisher
    This study examines the carbohydrate composition of Taenia solium whole oncosphere antigens (WOAs), in order to improve the understanding of the antigenicity of the T. solium...
  36. Castillo Iglesias H, Mouly S, Ducros A, Sarfati C, Sulahian A, Bergmann J. Late-onset eosinophilic chronic meningitis occurring 30 years after Taenia solium infestation in a white Caucasian woman. J Infect. 2006;53:e35-8 pubmed
    ..characterized by severe headache and chronic eosinophilic meningitis occurring 30 years after infestation with Taenia solium. The patient showed considerable improvement following treatment with albendazole and prednisone.
  37. Chavarria A, Fleury A, Bobes R, Morales J, Fragoso G, Sciutto E. A depressed peripheral cellular immune response is related to symptomatic neurocysticercosis. Microbes Infect. 2006;8:1082-9 pubmed
    ..This evidence supports the existence of two clear different immune profiles according to neurocysticercosis that is asymptomatic or symptomatic...
  38. da Silva M, Maia A, Espindola N, Machado L, Vaz A, Henrique Silva F. Recombinant expression of Taenia solium TS14 antigen and its utilization for immunodiagnosis of neurocysticercosis. Acta Trop. 2006;100:192-8 pubmed
    ..of neurocysticercosis (NC), its open reading frame (ORF) was amplified by RT-PCR from mRNA isolated from Taenia solium cysticerci...
  39. Nash T, Mahanty S, Garcia H. Corticosteroid use in neurocysticercosis. Expert Rev Neurother. 2011;11:1175-83 pubmed publisher
    The cystic larvae of Taenia solium commonly infect the human nervous system, resulting in neurocysticercosis, a major contributor to seizure disorders in most of the world...
  40. Victor B, Kanobana K, Gabriel S, Polman K, Deckers N, Dorny P, et al. Proteomic analysis of Taenia solium metacestode excretion-secretion proteins. Proteomics. 2012;12:1860-9 pubmed publisher
    The metacestode larval stage of Taenia solium is the causal agent of a zoonotic disease called cysticercosis...
  41. Pondja A, Neves L, Mlangwa J, Afonso S, Fafetine J, Willingham A, et al. Use of oxfendazole to control porcine cysticercosis in a high-endemic area of Mozambique. PLoS Negl Trop Dis. 2012;6:e1651 pubmed publisher
    ..of porcine cysticercosis using antigen ELISA (Ag-ELISA), as well as knowledge and practices related to Taenia solium transmission based on questionnaire interviews and observations...
  42. Avila G, Teran N, Aguilar Vega L, Maravilla P, Mata Miranda P, Flisser A. Laboratory animal models for human Taenia solium. Parasitol Int. 2006;55 Suppl:S99-S103 pubmed
    Human beings are the only hosts of adult Taenia solium; thus, many aspects of the host-parasite relationship are unknown...
  43. Almeida C, Ojopi E, Nunes C, Machado L, Takayanagui O, Livramento J, et al. Taenia solium DNA is present in the cerebrospinal fluid of neurocysticercosis patients and can be used for diagnosis. Eur Arch Psychiatry Clin Neurosci. 2006;256:307-10 pubmed
    ..The PCR amplification of the parasite DNA in the CSF enabled the correct identification of 29/30 cases (96.7 %). The PCR diagnosis of parasite DNA in the CSF may be a strong support for the diagnosis of neurocysticercosis...
  44. Guo Y, Wu D, Wang K, Sun S. Adjuvant effects of bacillus Calmette-Guerin DNA or CpG-oligonucleotide in the immune response to Taenia solium cysticercosis vaccine in porcine. Scand J Immunol. 2007;66:619-27 pubmed
    ..Four weeks after the last immunization, pigs were infected with Taenia solium eggs...
  45. Sikasunge C, Phiri I, Johansen M, Willingham A, Leifsson P. Host-cell apoptosis in Taenia solium-induced brain granulomas in naturally infected pigs. Parasitology. 2008;135:1237-42 pubmed publisher
    To assess whether apoptosis occurs in pig brain granulomas due to Taenia solium cysticerci, brain tissues from 30 pigs naturally infected with T...
  46. Hinojosa Juarez A, Sandoval Balanzario M, McManus D, Monroy Ostria A. Genetic similarity between cysticerci of Taenia solium isolated from human brain and from pigs. Infect Genet Evol. 2008;8:653-6 pubmed publisher
    Mitochondrial (mt) cox1 and ribosomal ITS1 DNA sequences from Taenia solium cysticercus isolates from pigs and cysticerci (racemose and cellulose types) from patients with neurocysticercosis were amplified by the polymerase chain ..
  47. Mayta H, Hancock K, Gilman R, Zamudio R, Castillo J, Levine M, et al. A novel Taenia solium protein that resembles troponin T proteins. J Parasitol. 2009;95:591-7 pubmed publisher
    b>Taenia solium Linnaeus, 1758 is responsible for taeniasis and cysticercosis, which are 2 serious health problems, particularly in developing countries. The attempt to identify a 22...
  48. Salim L, Ang A, Handali S, Tsang V. Seroepidemiologic survey of cysticercosis-taeniasis in four central highland districts of Papua, Indonesia. Am J Trop Med Hyg. 2009;80:384-8 pubmed
    ..7% and 10.7% for taeniasis, respectively). Our data show that the prevalence of cysticercosis and taeniasis are unchanged from that reported nearly 35 years ago at the beginning of cysticercosis-taeniasis epidemics in Papua, Indonesia...
  49. Barcelos I, Souza M, Pena J, Machado G, Moura L, Costa Cruz J. Genetic polymorphism in Taenia solium metacestodes from different Brazilian geographic areas. Mem Inst Oswaldo Cruz. 2012;107:24-30 pubmed
    The aim of the present study is to investigate genetic polymorphisms in Taenia solium metacestodes from different Brazilian geographical areas and to relate them to antibody recognition in serum samples of neurocysticercosis (NC) ..
  50. de Aluja A, Villalobos N, Nava G, Toledo A, Martínez J, Plancarte A, et al. Therapeutic capacity of the synthetic peptide-based vaccine against Taenia solium cysticercosis in pigs. Vaccine. 2005;23:4062-9 pubmed
    ..Thus, S3Pvac represents a powerful means of controlling cysticercosis infection in pigs...
  51. Montano S, Villaran M, Ylquimiche L, Figueroa J, Rodriguez S, Bautista C, et al. Neurocysticercosis: association between seizures, serology, and brain CT in rural Peru. Neurology. 2005;65:229-33 pubmed
    ..Although NCC is commonly seen in individuals with seizures in endemic areas, its role as a cause of epilepsy has been questioned on the basis of the poor methodology of published studies...
  52. Bouree P, Dumazedier D, Bisaro F, Resende P, Comoy J, Aghakhani N. Spinal cord cysticercosis: a case report. J Egypt Soc Parasitol. 2006;36:727-36 pubmed
    Cysticercosis caused by the infection with the larva of Taenia solium, common through out the world, is located in the muscles, the eyes and the central nervous system, but mostly in the brain. Spinal cord infection is rare...
  53. Rodriguez Hidalgo R, Benitez Ortiz W, Praet N, Saa L, Vercruysse J, Brandt J, et al. Taeniasis-cysticercosis in Southern Ecuador: assessment of infection status using multiple laboratory diagnostic tools. Mem Inst Oswaldo Cruz. 2006;101:779-82 pubmed
    b>Taenia solium-taeniasis and cysticercosis were studied in the human and porcine populations of a rural community in the Southern Ecuadorian Andes. From the 1059 inhabitants, 800 serum samples and 958 stool samples could be collected...
  54. Lescano A, Garcia H, Gilman R, Guezala M, Tsang V, Gavidia C, et al. Swine cysticercosis hotspots surrounding Taenia solium tapeworm carriers. Am J Trop Med Hyg. 2007;76:376-83 pubmed
    We estimated the Taenia solium swine cysticercosis risk gradient surrounding tapeworm carriers in seven rural communities in Peru. At baseline, the prevalences of taeniasis by microscopy and swine cysticercosis by serology were 1...
  55. Wang I, Fan P, Lu S, Fan C, Su K. Suppression of host Th1-type granulomatous inflammation by Taenia solium metacestodes is related to down-regulation of osteopontin gene expression. Int J Parasitol. 2008;38:239-48 pubmed
    ..In the present murine model, over 94% of Taenia solium metacestodes were viable and elicited no granulomatous inflammation, whereas parasites killed by praziquantel ..
  56. Willms K. Morphology and biochemistry of the pork tapeworm, Taenia solium. Curr Top Med Chem. 2008;8:375-82 pubmed
    This chapter describes the life cycle, general morphology and ultrastructure of the larval and adult stages of Taenia solium, a parasitic flatworm of humans found in underdeveloped countries...
  57. Hernandez M, Gonzalez L, Fleury A, Saenz B, Parkhouse R, Harrison L, et al. Neurocysticercosis: detection of Taenia solium DNA in human cerebrospinal fluid using a semi-nested PCR based on HDP2. Ann Trop Med Parasitol. 2008;102:317-23 pubmed publisher
    Human neurocysticercosis (NC) is caused by Taenia solium larvae lodged in the central nervous system. This disease is usually diagnosed by radiology but the results are not always clear-cut and so immunological assays are often also used...
  58. Sikasunge C, Johansen M, Phiri I, Willingham A, Leifsson P. The immune response in Taenia solium neurocysticercosis in pigs is associated with astrogliosis, axonal degeneration and altered blood-brain barrier permeability. Vet Parasitol. 2009;160:242-50 pubmed publisher
    ..to examine the immuno-pathological changes and the extent of neuronal damage caused by either viable or dead Taenia solium cysticerci during porcine neurocysticercosis...
  59. Pondja A, Neves L, Mlangwa J, Afonso S, Fafetine J, Willingham A, et al. Prevalence and risk factors of porcine cysticercosis in Angónia District, Mozambique. PLoS Negl Trop Dis. 2010;4:e594 pubmed publisher
    b>Taenia solium is an important zoonosis in many developing countries. Cysticercosis poses a serious public health risk and incurs sizeable economic losses to pig production...
  60. Assana E, Amadou F, Thys E, Lightowlers M, Zoli A, Dorny P, et al. Pig-farming systems and porcine cysticercosis in the north of Cameroon. J Helminthol. 2010;84:441-6 pubmed publisher
    ..was carried out to collect information on the pig-farming system and to identify potential risk factors for Taenia solium cysticercosis infection in pigs...
  61. Pant B, Devleesschauwer B, Shrestha P, Shrestha I, Praet N, Dorny P. Intraventricular Taenia solium neurocysticercosis: a report of three cases. JNMA J Nepal Med Assoc. 2011;51:192-5 pubmed
    Neurocysticercosis (NCC), caused by the pork tapeworm Taenia solium, is reported to be a common condition in Nepal. So far imaging diagnosis was mainstay of the diagnosis...
  62. Willms K, Presas A, Jiménez J, Landa A, Zurabian R, Ugarte M, et al. Taeniid tapeworm responses to in vitro glucose. Parasitol Res. 2005;96:296-301 pubmed
    Experimental taeniid strobilae from Taenia solium and T. crassiceps (WFU strain) were incubated for 0-72 h in 0, 5 or 20 mM glucose solutions and further exposed for 15 min to the gap junction fluorochrome Lucifer Yellow...
  63. Waloch M. [Cestode infections in Poland in 2003]. Przegl Epidemiol. 2005;59:331-5 pubmed
    ..solium, 32 by Taenia sp., 1 by Diphyllobothrium latum,. Moreover, 34 cases of cystic echinococcosis were also registered. The obtained results confirmed decreasing frequency of intestinal cestodes in Poland...
  64. Morales J, Martinez J, Garcia Castella J, Pena N, Maza V, Villalobos N, et al. Taenia solium: the complex interactions, of biological, social, geographical and commercial factors, involved in the transmission dynamics of pig cysticercosis in highly endemic areas. Ann Trop Med Parasitol. 2006;100:123-35 pubmed
    ..control of pig cysticercosis is to be effective it has to be based on good data on the local epidemiology of Taenia solium. In 2002-2003, in a cross-sectional study of pig cysticercosis in the Mexican state of Morelos, 1747 pigs that ..
  65. Cai G, Bae Y, Kim S, Na B, Kim T, Jiang M, et al. A membrane-associated metalloprotease of Taenia solium metacestode structurally related to the FACE-1/Ste24p protease family. Int J Parasitol. 2006;36:925-35 pubmed
    ..In this study, we have isolated a full-length cDNA putatively encoding a type I CaaX protease of the Taenia solium metacestode (TsM), which an agent causative of human neurocysticercosis...
  66. Gonzalez L, Ferrer E, Spickett A, Michael L, Vatta A, Garate T, et al. The Taenia saginata homologue of the major surface antigen of Echinococcus spp. is immunogenic and 97% identical to its Taenia solium homologue. Parasitol Res. 2007;101:1541-9 pubmed
    ..In addition, as we now demonstrate a 97% homology between TEG-Tsag and its Taenia solium homologue, TEG-Tsol, this latter molecule may have similar potential in the control of human and porcine ..
  67. Lee E, Kim S, Bae Y, Chung J, Suh M, Na B, et al. A hydrophobic ligand-binding protein of the Taenia solium metacestode mediates uptake of the host lipid: implication for the maintenance of parasitic cellular homeostasis. Proteomics. 2007;7:4016-30 pubmed
    ..We investigated the uptake of host lipids by a 150-kDa hydrophobic ligand-binding protein (HLBP) of Taenia solium metacestode, an agent causative of neurocysticercosis...
  68. Raccurt C, Agnamey P, Boncy J, Henrys J, Totet A. Seroprevalence of human Taenia solium cysticercosis in Haiti. J Helminthol. 2009;83:113-6 pubmed publisher
    Human Taenia solium cysticercosis is common in developing countries due to poor sanitary conditions and economics based on breeding livestock, especially pigs, with low hygiene standards...
  69. Bobes R, Fragoso G, Reyes Montes M, Duarte Escalante E, Vega R, de Aluja A, et al. Genetic diversity of Taenia solium cysticerci from naturally infected pigs of central Mexico. Vet Parasitol. 2010;168:130-5 pubmed publisher
    ..living in different geographic rural areas of central Mexico, is caused by one or more different specimens of Taenia solium tapeworm...
  70. Mkupasi E, Ngowi H, Nonga H. Prevalence of extra-intestinal porcine helminth infections and assessment of sanitary conditions of pig slaughter slabs in Dar es Salaam city, Tanzania. Trop Anim Health Prod. 2011;43:417-23 pubmed publisher
    ..Thus, there is a need to introduce appropriate control measures of parasitic infections in pigs...
  71. Lundström J, Salazar Anton F, Sherwood E, Andersson B, Lindh J. Analyses of an expressed sequence tag library from Taenia solium, Cysticerca. PLoS Negl Trop Dis. 2010;4:e919 pubmed publisher
    Neurocysticercosis is a disease caused by the oral ingestion of eggs from the human parasitic worm Taenia solium. Although drugs are available they are controversial because of the side effects and poor efficiency...
  72. Du W, Hu F, Yang Y, Hu D, Hu X, Yu X, et al. Molecular cloning, characterization, and immunolocalization of two lactate dehydrogenase homologous genes from Taenia solium. Parasitol Res. 2011;109:567-74 pubmed publisher
    ..dehydrogenase A (LDHA) and B (LDHB) homologues, respectively, were identified from the cDNA libraries of adult Taenia solium (T. solium)...
  73. Verma A, Prasad K, Cheekatla S, Nyati K, Paliwal V, Gupta R. Immune response in symptomatic and asymptomatic neurocysticercosis. Med Microbiol Immunol. 2011;200:255-61 pubmed publisher
  74. Mwape K, Praet N, Benitez Ortiz W, Muma J, Zulu G, Celi Erazo M, et al. Field evaluation of urine antigen detection for diagnosis of Taenia solium cysticercosis. Trans R Soc Trop Med Hyg. 2011;105:574-8 pubmed publisher
    Neuro)cysticercosis is an important zoonotic disease caused by infection with Taenia solium metacestode larvae. Existing immunodiagnostic techniques detect antibodies and circulating antigens (Ag) in serum and cerebrospinal fluid (CSF)...
  75. Gonzalez A, Bustos J, Jimenez J, Rodriguez M, Ramirez M, Gilman R, et al. Efficacy of diverse antiparasitic treatments for cysticercosis in the pig model. Am J Trop Med Hyg. 2012;87:292-6 pubmed
    b>Taenia solium cysticercosis infects pigs and humans. Because antiparasitic treatment for human cysticercosis has sub-optimal efficacy, alternative regimes are needed...
  76. León Cabrera S, Cruz Rivera M, Mendlovic F, Romero Valdovinos M, Vaughan G, Salazar A, et al. Immunological mechanisms involved in the protection against intestinal taeniosis elicited by oral immunization with Taenia solium calreticulin. Exp Parasitol. 2012;132:334-40 pubmed publisher
    Oral immunization with functional recombinant Taenia solium calreticulin (rTsCRT) induces 37% reduction in tapeworm burden in the experimental model of intestinal taeniosis in hamsters...
  77. Singh A, Prasad K, Prasad A, Tripathi M, Gupta R, Husain N. Immune responses to viable and degenerative metacestodes of Taenia solium in naturally infected swine. Int J Parasitol. 2013;43:1101-7 pubmed publisher
    Neurocysticercosis, caused by the larvae of the pork tapeworm Taenia solium, is the most common helminth infection of the CNS in humans worldwide. There is no existing animal model of neurocysticercosis that resembles human infection...
  78. Pawlowski Z, Allan J, Sarti E. Control of Taenia solium taeniasis/cysticercosis: from research towards implementation. Int J Parasitol. 2005;35:1221-32 pubmed
    Theoretically, considering the biology of its transmission and reservoirs, global eradication of Taenia solium taeniasis and cysticercosis is feasible...
  79. Del Brutto O. Neurocysticercosis. Semin Neurol. 2005;25:243-51 pubmed
    ..The disease occurs when humans become the intermediate host in the life cycle of Taenia solium by ingesting its eggs from contaminated food...
  80. Morales J, Martínez J, Rosetti M, Fleury A, Maza V, Hernandez M, et al. Spatial distribution of Taenia solium porcine cysticercosis within a rural area of Mexico. PLoS Negl Trop Dis. 2008;2:e284 pubmed publisher
    Cysticercosis is caused by Taenia solium, a parasitic disease that affects humans and rurally bred pigs in developing countries...
  81. Atluri S, Singhi P, Khandelwal N, Malla N. Evaluation of excretory secretory and 10-30 kDa antigens of Taenia solium Cysticerci by EITB assay for the diagnosis of neurocysticercosis. Parasite Immunol. 2009;31:151-5 pubmed publisher
    Neurocysticercosis (NCC), caused by the presence of Taenia solium Cysticerci in the Central Nervous System is the most common neurological disease of parasite aetiology...
  82. Sikasunge C, Phiri I, Willingham A, Johansen M. Dynamics and longevity of maternally-acquired antibodies to Taenia solium in piglets born to naturally infected sows. Vet J. 2010;184:318-21 pubmed publisher
    ..investigate the longevity of maternally-acquired specific antibody (Ab) isotypes in piglets born to sows with Taenia solium cysticercosis...
  83. Ferrer E, Martínez Escribano J, Barderas M, Gonzalez L, Cortéz M, Dávila I, et al. Peptide epitopes of the Taenia solium antigen Ts8B2 are immunodominant in human and porcine cysticercosis. Mol Biochem Parasitol. 2009;168:168-71 pubmed publisher
    Ts8B2 is a gene which encodes for a member of the Taenia solium metacestode 8kDa antigen family...
  84. Martinez Hernandez F, Jimenez Gonzalez D, Chenillo P, Alonso Fernandez C, Maravilla P, Flisser A. Geographical widespread of two lineages of Taenia solium due to human migrations: can population genetic analysis strengthen this hypothesis?. Infect Genet Evol. 2009;9:1108-14 pubmed publisher
    ..In this paper we discuss, with a new analysis of published data, the phylogenetic hypothesis of two genotypes of Taenia solium previously suggested. Sequences of mitochondrial (co1, cob, nad) and nuclear (18S+ITS1+5...
  85. Gazarian K, Solis C, Gazarian T, Rowley M, Laclette J. Synthetic peptide-targeted selection of phage display mimotopes highlights immunogenic features of ?-helical vs non-helical epitopes of Taenia solium paramyosin: implications for parasite- and host-protective roles of the protein. Peptides. 2012;34:232-41 pubmed publisher
    Paramyosin of the pig-human parasite Taenia solium (TPmy) is a ?-helical protein located on the worm surface that is suggested to fulfill an immunomodulatory role protecting the parasite against host immune system...
  86. Gazarian K, Rowlay M, Gazarian T, Vazquez Buchelli J, Hernández Gonzáles M. Mimotope peptides selected from phage display combinatorial library by serum antibodies of pigs experimentally infected with Taenia solium as leads to developing diagnostic antigens for human neurocysticercosis. Peptides. 2012;38:381-8 pubmed publisher
    Neurocysticercosis is caused by penetration of the tapeworm Taenia solium larvae into the central nervous system resulting in a diverse range of neurologic complications including epilepsy in endemic areas that globalization spreads ..
  87. Hancock K, Pattabhi S, Whitfield F, Yushak M, Lane W, Garcia H, et al. Characterization and cloning of T24, a Taenia solium antigen diagnostic for cysticercosis. Mol Biochem Parasitol. 2006;147:109-17 pubmed
    ..final diagnostic antigen of the lentil lectin purified glycoproteins (LLGP) extracted from the larval stage of Taenia solium has been characterized, cloned, and expressed...
  88. Rodriguez M, Rodriguez S, Gonzalez A, Verastegui M, Bernal T, Jimenez J, et al. Can Taenia solium latent post-oncospheral stages be found in muscle tissue of cysticercosis-infected pigs (Sus scrofa)?. J Parasitol. 2006;92:199-201 pubmed
    The existence of latent Taenia solium post-oncospheral stages in the tissues of infected pigs has been postulated...
  89. Wang K, Guo Y, Li K, Lu Y, Zhang Y, Sun S, et al. Molecular characterization and anticoagulant activity of a novel annexin derived from the Taenia solium. Acta Trop. 2006;99:165-72 pubmed
    A novel annexin gene was isolated from the Taenia solium cDNA library by degenerate PCR...
  90. Sahu P, Parija S, Narayan S, Kumar D. Evaluation of an IgG-ELISA strategy using Taenia solium metacestode somatic and excretory-secretory antigens for diagnosis of neurocysticercosis revealing biological stage of the larvae. Acta Trop. 2009;110:38-45 pubmed publisher
    ..The present study describes evaluation of ELISAs using Taenia solium metacestode somatic and excretory-secretory (ES) antigens for detection of anti-T...
  91. Escobedo G, Romano M, Morales Montor J. Differential in vitro effects of insulin on Taenia crassiceps and Taenia solium cysticerci. J Helminthol. 2009;83:403-12 pubmed publisher
    ..in murine cysticercosis (Taenia crassiceps), and increase the frequency of porcine cysticercosis caused by Taenia solium. In the present study, we report the in vitro effect of insulin on the larval stages of T...
  92. Kim S, Bae Y, Yang Y, Hong S, Kong Y. Paralogous proteins comprising the 150 kDa hydrophobic-ligand-binding-protein complex of the Taenia solium metacestode have evolved non-overlapped binding affinities toward fatty acid analogs. Int J Parasitol. 2011;41:1207-15 pubmed publisher
    We previously identified a hydrophobic-ligand-binding protein (HLBP) of the Taenia solium metacestode (TsM), which might be involved in the uptake of fatty acids (FAs) from host environments...