caenorhabditis

Summary

Summary: A genus of small free-living nematodes. Two species, CAENORHABDITIS ELEGANS and C. briggsae are much used in studies of genetics, development, aging, muscle chemistry, and neuroanatomy.

Top Publications

  1. Aroian R, Koga M, Mendel J, Ohshima Y, Sternberg P. The let-23 gene necessary for Caenorhabditis elegans vulval induction encodes a tyrosine kinase of the EGF receptor subfamily. Nature. 1990;348:693-9 pubmed
    The let-23 gene is required for induction of the Caenorhabditis elegans vulva. It is shown that let-23 encodes a putative tyrosine kinase of the epidermal growth factor receptor subfamily...
  2. Cutter A, Felix M, Barrière A, Charlesworth D. Patterns of nucleotide polymorphism distinguish temperate and tropical wild isolates of Caenorhabditis briggsae. Genetics. 2006;173:2021-31 pubmed
    b>Caenorhabditis briggsae provides a natural comparison species for the model nematode C. elegans, given their similar morphology, life history, and hermaphroditic mode of reproduction. Despite C...
  3. Howe D, Denver D. Muller's Ratchet and compensatory mutation in Caenorhabditis briggsae mitochondrial genome evolution. BMC Evol Biol. 2008;8:62 pubmed publisher
    ..We characterized mitochondrial genome evolutionary processes in Caenorhabditis briggsae natural isolates to show that numerous lineages experience a high incidence of nonsynonymous ..
  4. Gimond C, Jovelin R, Han S, Ferrari C, Cutter A, Braendle C. Outbreeding depression with low genetic variation in selfing Caenorhabditis nematodes. Evolution. 2013;67:3087-101 pubmed publisher
    ..we investigate inbreeding and outbreeding depression in self-fertile androdioecious nematodes, focusing on Caenorhabditis sp. 11...
  5. Hodgkin J. Sex determination compared in Drosophila and Caenorhabditis. Nature. 1990;344:721-8 pubmed
    ..In contrast, the underlying molecular mechanisms appear to be very different in these two species. Developmental processes such as sex determination need not be strongly conserved in evolution. ..
  6. Hedgecock E, Culotti J, Hall D, Stern B. Genetics of cell and axon migrations in Caenorhabditis elegans. Development. 1987;100:365-82 pubmed
    The Caenorhabditis elegans epidermis comprises 78 cells which cover the external surface of the embryo as a single cell layer...
  7. Hodgkin J. A genetic analysis of the sex-determining gene, tra-1, in the nematode Caenorhabditis elegans. Genes Dev. 1987;1:731-45 pubmed
    The normal sexes of Caenorhabditis elegans are the self-fertilizing hermaphrodite (XX) and the male (XO). The autosomal gene tra-1 is a major switch gene controlling sexual phenotype...
  8. Baer C, Phillips N, Ostrow D, Avalos A, Blanton D, Boggs A, et al. Cumulative effects of spontaneous mutations for fitness in Caenorhabditis: role of genotype, environment and stress. Genetics. 2006;174:1387-95 pubmed
    ..b>Caenorhabditis briggsae and C. elegans have similar demography at 20 degrees, but C...
  9. Dey A, Chan C, Thomas C, Cutter A. Molecular hyperdiversity defines populations of the nematode Caenorhabditis brenneri. Proc Natl Acad Sci U S A. 2013;110:11056-60 pubmed publisher
    The biology of Sydney Brenner's eponymous species of nematode, Caenorhabditis brenneri, is little known to science, despite its famous sibling Caenorhabditis elegans. Here we demonstrate that C...

More Information

Publications182 found, 100 shown here

  1. Okimoto R, Macfarlane J, Clary D, Wolstenholme D. The mitochondrial genomes of two nematodes, Caenorhabditis elegans and Ascaris suum. Genetics. 1992;130:471-98 pubmed
    The nucleotide sequences of the mitochondrial DNA (mtDNA) molecules of two nematodes, Caenorhabditis elegans [13,794 nucleotide pairs (ntp)], and Ascaris suum (14,284 ntp) are presented and compared...
  2. Krause M, Fire A, Harrison S, Priess J, Weintraub H. CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis. Cell. 1990;63:907-19 pubmed
  3. Lin K, Broitman Maduro G, Hung W, Cervantes S, Maduro M. Knockdown of SKN-1 and the Wnt effector TCF/POP-1 reveals differences in endomesoderm specification in C. briggsae as compared with C. elegans. Dev Biol. 2009;325:296-306 pubmed publisher
    ..Our results suggest that integration of Wnt-dependent and Wnt-independent cell fate specification pathways within the Caenorhabditis genus can occur in different ways.
  4. Kiontke K, Felix M, Ailion M, Rockman M, Braendle C, Pénigault J, et al. A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruits. BMC Evol Biol. 2011;11:339 pubmed publisher
    The nematode Caenorhabditis elegans is a major laboratory model in biology. Only ten Caenorhabditis species were available in culture at the onset of this study. Many of them, like C...
  5. Paschinger K, Rendic D, Wilson I. Revealing the anti-HRP epitope in Drosophila and Caenorhabditis. Glycoconj J. 2009;26:385-95 pubmed publisher
    ..This peculiar finding was later expanded to other invertebrate species including Caenorhabditis elegans, which were also shown to bear anti-HRP epitopes...
  6. Clark K, Howe D, Gafner K, Kusuma D, Ping S, Estes S, et al. Selfish little circles: transmission bias and evolution of large deletion-bearing mitochondrial DNA in Caenorhabditis briggsae nematodes. PLoS ONE. 2012;7:e41433 pubmed publisher
    ..DNA bearing large heteroplasmic deletions including nad5 gene sequences (nad5? mtDNA), in the nematode Caenorhabditis briggsae. The deletion is widespread in C...
  7. Leggett D, Candido P. Biochemical characterization of Caenorhabditis elegans UBC-1: self-association and auto-ubiquitination of a RAD6-like ubiquitin-conjugating enzyme in vitro. Biochem J. 1997;327 ( Pt 2):357-61 pubmed
    The Caenorhabditis elegans ubiquitin-conjugating enzyme UBC-1 is distinct from other RAD6 homologues in possessing a C-terminal tail 40 amino acid residues long [Leggett, Jones and Candido (1995) DNA Cell Biol. 14, 883-891]...
  8. Rivas E, Eddy S. Noncoding RNA gene detection using comparative sequence analysis. BMC Bioinformatics. 2001;2:8 pubmed
    ..We have implemented this approach as a program, QRNA, which we consider to be a prototype structural noncoding RNA genefinder. Tests suggest that this approach detects noncoding RNA genes with a fair degree of reliability. ..
  9. Wang P, Ruvinsky I. Computational prediction of Caenorhabditis box H/ACA snoRNAs using genomic properties of their host genes. RNA. 2010;16:290-8 pubmed publisher
    ..Searches in the genomes of Caenorhabditis elegans and the closely related Caenorhabditis briggsae suggest that our method performs well compared to ..
  10. Pénigault J, Felix M. Evolution of a system sensitive to stochastic noise: P3.p cell fate in Caenorhabditis. Dev Biol. 2011;357:419-27 pubmed publisher
    ..Here we examine the evolutionary properties of this stochastic variation in P3.p fate. In the Caenorhabditis genus, high P3.p competence is ancestral and reduction in P3.p competence and division frequency occurred in C...
  11. Felix M, Duveau F. Population dynamics and habitat sharing of natural populations of Caenorhabditis elegans and C. briggsae. BMC Biol. 2012;10:59 pubmed publisher
    The nematode Caenorhabditis elegans is a major model organism in laboratory biology. Very little is known, however, about its ecology, including where it proliferates. In the past, C...
  12. Marshall S, McGhee J. Coordination of ges-1 expression between the Caenorhabditis pharynx and intestine. Dev Biol. 2001;239:350-63 pubmed
    We have previously shown that the Caenorhabditis elegans gut-specific esterase gene (Ce-ges-1) has the unusual ability to be expressed in different modules of the embryonic digestive tract (anterior pharynx, posterior pharynx, and rectum) ..
  13. Aevermann B, Waters E. A comparative genomic analysis of the small heat shock proteins in Caenorhabditis elegans and briggsae. Genetica. 2008;133:307-19 pubmed
    ..We have identified 18 sHSPs in the Caenorhabditis elegans genome and 20 sHSPs in the Caenorhabditis briggsae genome...
  14. Mazroui R, Puoti A, Kramer A. Splicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viability. RNA. 1999;5:1615-31 pubmed
    ..We have isolated cDNAs encoding SF1 from Drosophila (Dm) and Caenorhabditis (Ce)...
  15. Graustein A, Gaspar J, Walters J, Palopoli M. Levels of DNA polymorphism vary with mating system in the nematode genus caenorhabditis. Genetics. 2002;161:99-107 pubmed
    ..variation, levels of DNA sequence polymorphism were compared among three closely related species in the genus Caenorhabditis: two self-fertilizing species, Caenorhabditis elegans and C. briggsae, and one cross-fertilizing species, C...
  16. Cutter A. Divergence times in Caenorhabditis and Drosophila inferred from direct estimates of the neutral mutation rate. Mol Biol Evol. 2008;25:778-86 pubmed publisher
    ..The classic biological models Caenorhabditis and Drosophila are examples of such problem taxa...
  17. Abebe E, Jumba M, Bonner K, Gray V, Morris K, Thomas W. An entomopathogenic Caenorhabditis briggsae. J Exp Biol. 2010;213:3223-9 pubmed publisher
    b>Caenorhabditis elegans is a premier model organism upon which considerable knowledge of basic cell and developmental biology has been built...
  18. Mello C, Kramer J, Stinchcomb D, Ambros V. Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 1991;10:3959-70 pubmed
    ..behavioral marker, rol-6(su-1006), and an efficient microinjection procedure which facilitate the recovery of Caenorhabditis elegans transformants. We use these tools to study the mechanism of C.elegans DNA transformation...
  19. Zorio D, Lea K, Blumenthal T. Cloning of Caenorhabditis U2AF65: an alternatively spliced RNA containing a novel exon. Mol Cell Biol. 1997;17:946-53 pubmed
    ..Because Caenorhabditis elegans introns lack both polypyrimidine tract and branch point consensus sequences but have a very highly ..
  20. Ostrow D, Phillips N, Avalos A, Blanton D, Boggs A, Keller T, et al. Mutational bias for body size in rhabditid nematodes. Genetics. 2007;176:1653-61 pubmed
    ..are very consistent with previous studies of mutations underlying fitness in the same strains: two strains of Caenorhabditis briggsae decline in body size about twice as fast as two strains of C...
  21. Raboin M, Timko A, Howe D, Felix M, Denver D. Evolution of Caenorhabditis mitochondrial genome pseudogenes and Caenorhabditis briggsae natural isolates. Mol Biol Evol. 2010;27:1087-96 pubmed publisher
    ..The nematode species Caenorhabditis briggsae harbors two mitochondrial DNA (mtDNA) pseudogenes, named Psinad5-1 and Psinad5-2, presumably derived ..
  22. Levin M, Hashimshony T, Wagner F, Yanai I. Developmental milestones punctuate gene expression in the Caenorhabditis embryo. Dev Cell. 2012;22:1101-8 pubmed publisher
    ..Here we demonstrate that, at the molecular level, embryonic development in five Caenorhabditis species proceeds through two distinct milestones in which the transcriptome is resistant to differences in ..
  23. Clokey G, Jacobson L. The autofluorescent "lipofuscin granules" in the intestinal cells of Caenorhabditis elegans are secondary lysosomes. Mech Ageing Dev. 1986;35:79-94 pubmed
    The nematode Caenorhabditis elegans contains autofluorescent lipofuscin granules, located exclusively in the 32-34 intestinal cells...
  24. Schriefer L, Waterson R. Phosphorylation of the N-terminal region of Caenorhabditis elegans paramyosin. J Mol Biol. 1989;207:451-4 pubmed
    Paramyosin from Caenorhabditis elegans was examined for post-translational modification by phosphorylation. Paramyosin purified from populations of mixed-age animals contained 0.7 to 2.0 moles of phosphate per mole of paramyosin...
  25. Hosono R, Mitsui Y, Sato Y, Aizawa S, Miwa J. Life span of the wild and mutant nematode Caenorhabditis elegans. Effects of sex, sterilization, and temperature. Exp Gerontol. 1982;17:163-72 pubmed
    The survival of Caenorhabditis elegans was studied comparing animals of different sexes, sterilized animals, and animals grown at different temperatures as a prelude to more detailed cytological and genetic analysis of aged nematodes...
  26. Hoogewijs D, Geuens E, Dewilde S, Vierstraete A, Moens L, Vinogradov S, et al. Wide diversity in structure and expression profiles among members of the Caenorhabditis elegans globin protein family. BMC Genomics. 2007;8:356 pubmed
    ..Globin ZK637.13 is not responsive to oxygen deprivation and regulated by the Ins/IGF pathway only suggesting that this globin may contribute to the life maintenance program. ..
  27. Hosono R, Kamiya Y. Additional genes which result in an elevation of acetylcholine levels by mutations in Caenorhabditis elegans. Neurosci Lett. 1991;128:243-4 pubmed
    ..These results suggest that the 7 genes are involved in some related functions. ..
  28. Hodgkin J, Papp A, Pulak R, Ambros V, Anderson P. A new kind of informational suppression in the nematode Caenorhabditis elegans. Genetics. 1989;123:301-13 pubmed
    Independent reversions of mutations affecting three different Caenorhabditis elegans genes have each yielded representatives of the same set of extragenic suppressors...
  29. Ambros V, Horvitz H. Heterochronic mutants of the nematode Caenorhabditis elegans. Science. 1984;226:409-16 pubmed
    Mutations in the Caenorhabditis elegans genes lin-14, lin-28, and lin-29 cause heterochronic developmental defects: the timing of specific developmental events in several tissues is altered relative to the timing of events in other ..
  30. Hada K, Asahina M, Hasegawa H, Kanaho Y, Slack F, Niwa R. The nuclear receptor gene nhr-25 plays multiple roles in the Caenorhabditis elegans heterochronic gene network to control the larva-to-adult transition. Dev Biol. 2010;344:1100-9 pubmed publisher
    Developmental timing in the nematode Caenorhabditis elegans is controlled by heterochronic genes, mutations in which cause changes in the relative timing of developmental events...
  31. Liu Z, Ambros V. Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans. Genes Dev. 1989;3:2039-49 pubmed
    ..Our results further suggest that dauer larva morphogenesis by hypodermal cells requires that lin-28 acts to inhibit lin-29 during early larval stages. ..
  32. Davis B, Anderson G, Dusenbery D. Total luminescence spectroscopy of fluorescence changes during aging in Caenorhabditis elegans. Biochemistry. 1982;21:4089-95 pubmed
    ..spectroscopy was employed to characterize and quantitate age-related changes in fluorescence in the nematode Caenorhabditis elegans, an established model for aging research...
  33. Liu Q. Gene conversion and positive selection driving the evolution of the Caenorhabditis ssp. ZIM/HIM-8 protein family. J Mol Evol. 2009;68:217-26 pubmed publisher
    ..The zim/him-8 genes from three Caenorhabditis species were contrasted in an effort to investigate the mechanisms driving their evolution...
  34. Salomon M, Ostrow D, Phillips N, Blanton D, Bour W, Keller T, et al. Comparing mutational and standing genetic variability for fitness and size in Caenorhabditis briggsae and C. elegans. Genetics. 2009;183:685-92, 1SI-19SI pubmed publisher
    ..success (approximately fitness) and body volume in two species of self-fertilizing rhabditid nematodes, Caenorhabditis briggsae and C. elegans, which the evidence suggests have different mutation rates...
  35. Dibb N, Maruyama I, Krause M, Karn J. Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family. J Mol Biol. 1989;205:603-13 pubmed
    The sequences of three myosin heavy chain (MHC) genes from Caenorhabditis elegans, myo-1, 2 and 3, are presented. These genes, together with unc-54, comprise the entire nematode sacromeric MHC family...
  36. Prasad A, Croydon Sugarman M, Murray R, Cutter A. Temperature-dependent fecundity associates with latitude in Caenorhabditis briggsae. Evolution. 2011;65:52-63 pubmed publisher
    ..latitude, and here we investigate its effects on the fecundity of self-fertilizing nematodes of the species Caenorhabditis briggsae that exhibits strong genetically based differentiation in association with latitude...
  37. Aroian R, Sternberg P. Multiple functions of let-23, a Caenorhabditis elegans receptor tyrosine kinase gene required for vulval induction. Genetics. 1991;128:251-67 pubmed
    ..tyrosine kinase of the epidermal growth factor (EGF) receptor subfamily, has multiple functions during Caenorhabditis elegans development...
  38. Sulston J, Albertson D, Thomson J. The Caenorhabditis elegans male: postembryonic development of nongonadal structures. Dev Biol. 1980;78:542-76 pubmed
  39. Krause M, Wild M, Rosenzweig B, Hirsh D. Wild-type and mutant actin genes in Caenorhabditis elegans. J Mol Biol. 1989;208:381-92 pubmed
    We have sequenced the four actin genes of Caenorhabditis elegans. These four genes encode typical invertebrate actins and are highly homologous, differing from each other by, at most, three amino acid residues...
  40. Kemphues K, Kusch M, Wolf N. Maternal-effect lethal mutations on linkage group II of Caenorhabditis elegans. Genetics. 1988;120:977-86 pubmed
    We have analyzed a set of linkage group (LG) II maternal-effect lethal mutations in Caenorhabditis elegans isolated by a new screening procedure...
  41. Lewis J, Wu C, Berg H, Levine J. The genetics of levamisole resistance in the nematode Caenorhabditis elegans. Genetics. 1980;95:905-28 pubmed
    We have characterized a small group of genes (13 loci) in the nematode Caenorhabditis elegans that, when mutated, confer resistance to the potent anthelmintic levamisole...
  42. Phillips N, Salomon M, Custer A, Ostrow D, Baer C. Spontaneous mutational and standing genetic (co)variation at dinucleotide microsatellites in Caenorhabditis briggsae and Caenorhabditis elegans. Mol Biol Evol. 2009;26:659-69 pubmed publisher
    ..microsatellite repeats in four sets of 250-generation mutation accumulation (MA) lines, two in the species Caenorhabditis briggsae and two in Caenorhabditis elegans, and compare the mutational variation with the standing variation ..
  43. Siddiqui S, Aamodt E, Rastinejad F, Culotti J. Anti-tubulin monoclonal antibodies that bind to specific neurons in Caenorhabditis elegans. J Neurosci. 1989;9:2963-72 pubmed
    ..that bind to 2 different subpopulations of identified neurons in the simple nervous system of the nematode Caenorhabditis elegans. The antibodies also recognize specific tubulin isotypes from C...
  44. Stothard P, Hansen D, Pilgrim D. Evolution of the PP2C family in Caenorhabditis: rapid divergence of the sex-determining protein FEM-2. J Mol Evol. 2002;54:267-82 pubmed
    ..the causes and functional significance of rapid sex-determining protein evolution we compared three Caenorhabditis elegans genes encoding members of the protein phosphatase 2C (PP2C) family with their orthologs from another ..
  45. Thomas J, Kelley J, Robertson H, Ly K, Swanson W. Adaptive evolution in the SRZ chemoreceptor families of Caenorhabditis elegans and Caenorhabditis briggsae. Proc Natl Acad Sci U S A. 2005;102:4476-81 pubmed
    ..possibility of positive selection acting on members of the putative seven-pass chemoreceptor superfamily in Caenorhabditis elegans, which comprises approximately 1,300 genes encoding seven-pass G protein-coupled receptors (GPCRs)...
  46. Zhao Z, Boyle T, Bao Z, Murray J, Mericle B, Waterston R. Comparative analysis of embryonic cell lineage between Caenorhabditis briggsae and Caenorhabditis elegans. Dev Biol. 2008;314:93-9 pubmed publisher
    Comparative genomic analysis of important signaling pathways in Caenorhabditis briggsae and Caenorhabditis elegans reveals both conserved features and also differences...
  47. Zhu G, Chen H, Wu X, Zhou Y, Lu J, Chen H, et al. A modified n-3 fatty acid desaturase gene from Caenorhabditis briggsae produced high proportion of DHA and DPA in transgenic mice. Transgenic Res. 2008;17:717-25 pubmed publisher
    ..the n-3 fatty acid desaturase gene (sFat-1) synthesized from revised and optimized codons based on roundworm Caenorhabditis briggsae genomic gene for enhanced expression in mammals was successfully expressed in Chinese hamster ovary (..
  48. Bird D, Riddle D. Molecular cloning and sequencing of ama-1, the gene encoding the largest subunit of Caenorhabditis elegans RNA polymerase II. Mol Cell Biol. 1989;9:4119-30 pubmed
    ..the largest subunit of RNA polymerase II in Drosophila melanogaster, have been isolated from the nematode Caenorhabditis elegans...
  49. Hoyos E, Kim K, Milloz J, Barkoulas M, Pénigault J, Munro E, et al. Quantitative variation in autocrine signaling and pathway crosstalk in the Caenorhabditis vulval network. Curr Biol. 2011;21:527-38 pubmed publisher
    ..The intercellular signaling network underlying Caenorhabditis vulval development specifies three fates in a row of six precursor cells, yielding a quasi-invariant 3°3°2°..
  50. Greenwald I, Seydoux G. Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature. 1990;346:197-9 pubmed
    Certain cell fate decisions are specified by cell-cell interactions during the development of the nematode Caenorhabditis elegans. For example, in a wild-type hermaphrodite gonad, two cells, Z1.ppp and Z4...
  51. Sternberg P, Horvitz H. lin-17 mutations of Caenorhabditis elegans disrupt certain asymmetric cell divisions. Dev Biol. 1988;130:67-73 pubmed
    ..The lin-17 gene of the nematode Caenorhabditis elegans is an excellent candidate for being such a gene...
  52. Nayak S, Goree J, Schedl T. fog-2 and the evolution of self-fertile hermaphroditism in Caenorhabditis. PLoS Biol. 2005;3:e6 pubmed
    ..To overcome this difficulty, we compared the genes in the germline sex determination pathways of Caenorhabditis elegans and C. briggsae, two Caenorhabditis species with similar reproductive systems and sequenced genomes...
  53. Snoek L, van der Velde K, Arends D, Li Y, Beyer A, Elvin M, et al. WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp. Nucleic Acids Res. 2013;41:D738-43 pubmed publisher
    ..easily accessible database enabling search, comparative analysis and meta-analysis of all data on variation in Caenorhabditis spp...
  54. Cox G, Staprans S, Edgar R. The cuticle of Caenorhabditis elegans. II. Stage-specific changes in ultrastructure and protein composition during postembryonic development. Dev Biol. 1981;86:456-70 pubmed
  55. Rogalski T, Golomb M, Riddle D. Mutant Caenorhabditis elegans RNA polymerase II with a 20,000-fold reduced sensitivity to alpha-amanitin. Genetics. 1990;126:889-98 pubmed
    ..Rpo II activity in isolated Caenorhabditis elegans cell nuclei is inhibited 50% by alpha-amanitin at a concentration of 150 micrograms/ml, making this ..
  56. Combes D, Fedon Y, Grauso M, Toutant J, Arpagaus M. Four genes encode acetylcholinesterases in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae. cDNA sequences, genomic structures, mutations and in vivo expression. J Mol Biol. 2000;300:727-42 pubmed
    ..full coding sequences and the genomic organization of the four genes encoding acetylcholinesterase (AChE) in Caenorhabditis elegans and Caenorhabditis briggsae, in relation to the properties of the encoded enzymes...
  57. Witherspoon D, Robertson H. Neutral evolution of ten types of mariner transposons in the genomes of Caenorhabditis elegans and Caenorhabditis briggsae. J Mol Evol. 2003;56:751-69 pubmed
    ..mariner transposable elements (232 individual sequences) are present in the completed genomic DNA sequence of Caenorhabditis elegans and the partial sequence of Caenorhabditis briggsae...
  58. Cutter A, Baird S, Charlesworth D. High nucleotide polymorphism and rapid decay of linkage disequilibrium in wild populations of Caenorhabditis remanei. Genetics. 2006;174:901-13 pubmed
    The common ancestor of the self-fertilizing nematodes Caenorhabditis elegans and C. briggsae must have reproduced by obligate outcrossing, like most species in this genus...
  59. Dolgin E, Charlesworth B, Cutter A. Population frequencies of transposable elements in selfing and outcrossing Caenorhabditis nematodes. Genet Res (Camb). 2008;90:317-29 pubmed publisher
    ..population frequencies of transposable elements (TEs) in natural populations of the self-fertilizing nematode Caenorhabditis elegans and its outcrossing relative Caenorhabditis remanei...
  60. Freyd G, Kim S, Horvitz H. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11. Nature. 1990;344:876-9 pubmed
    The gene lin-11 is required for the asymmetric division of a vulval precursor cell type in the nematode Caenorhabditis elegans...
  61. Chalfie M, Sulston J. Developmental genetics of the mechanosensory neurons of Caenorhabditis elegans. Dev Biol. 1981;82:358-70 pubmed
  62. LaMunyon C, Ward S. Evolution of sperm size in nematodes: sperm competition favours larger sperm. Proc Biol Sci. 1999;266:263-7 pubmed
    In the free-living rhabditid nematode Caenorhabditis elegans, sperm size is a determinant of sperm competitiveness...
  63. Chen P, Cho S, Jin S, Ellis R. Specification of germ cell fates by FOG-3 has been conserved during nematode evolution. Genetics. 2001;158:1513-25 pubmed
    ..To analyze this phenomenon, we are studying species of the genus Caenorhabditis. These animals use one of two different mating systems-male/hermaphroditic, like the model organism ..
  64. Yook K, Harris T, Bieri T, Cabunoc A, Chan J, Chen W, et al. WormBase 2012: more genomes, more data, new website. Nucleic Acids Res. 2012;40:D735-41 pubmed publisher
    ..We report on the growth of our database and on our work in keeping pace with the growing demand for data, efforts to anticipate the requirements of users and new collaborations with the larger science community. ..
  65. Perkins L, Hedgecock E, Thomson J, Culotti J. Mutant sensory cilia in the nematode Caenorhabditis elegans. Dev Biol. 1986;117:456-87 pubmed
    ..The cat-6 (e1861) mutation disrupts the tubular bodies of the CEP mechanocilia. A cryophilic thermotaxis mutant, ttx-1 (p767), lacks fingers on the AFD dendrite, suggesting this neuron is thermosensory. ..
  66. Braendle C, Felix M. Sex determination: ways to evolve a hermaphrodite. Curr Biol. 2006;16:R468-71 pubmed
    Most species of the nematode genus Caenorhabditis reproduce through males and females; C. elegans and C. briggsae, however, produce self-fertile hermaphrodites instead of females...
  67. Levin J, Horvitz H. The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction. J Cell Biol. 1992;117:143-55 pubmed
    ..is one of a set of five interacting genes involved in the regulation or coordination of muscle contraction in Caenorhabditis elegans...
  68. Okimoto R, Macfarlane J, Wolstenholme D. Evidence for the frequent use of TTG as the translation initiation codon of mitochondrial protein genes in the nematodes, Ascaris suum and Caenorhabditis elegans. Nucleic Acids Res. 1990;18:6113-8 pubmed
    ..alignments of nucleotide sequences of mitochondrial (mt) DNA molecules of the nematode worms Ascaris suum and Caenorhabditis elegans indicate that in six of the mt-protein genes of A. suum and three of the mt-protein genes of C...
  69. Herr W, Sturm R, Clerc R, Corcoran L, Baltimore D, Sharp P, et al. The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev. 1988;2:1513-6 pubmed
  70. Gilleard J, Barry J, Johnstone I. cis regulatory requirements for hypodermal cell-specific expression of the Caenorhabditis elegans cuticle collagen gene dpy-7. Mol Cell Biol. 1997;17:2301-11 pubmed
    The Caenorhabditis elegans cuticle collagens are encoded by a multigene family of between 50 and 100 members and are the major component of the nematode cuticular exoskeleton...
  71. Curwen V, Eyras E, Andrews T, Clarke L, Mongin E, Searle S, et al. The Ensembl automatic gene annotation system. Genome Res. 2004;14:942-50 pubmed
    ..gambiae genome sequence analysis. Here we describe in detail the gene-building system and the algorithms involved. All code and data are freely available from http://www.ensembl.org. ..
  72. Haerty W, Artieri C, Khezri N, Singh R, Gupta B. Comparative analysis of function and interaction of transcription factors in nematodes: extensive conservation of orthology coupled to rapid sequence evolution. BMC Genomics. 2008;9:399 pubmed publisher
    ..The nematode Caenorhabditis elegans is an established model organism for the study of the roles of TFs in controlling the spatiotemporal ..
  73. Cutter A, Wang G, Ai H, Peng Y. Influence of finite-sites mutation, population subdivision and sampling schemes on patterns of nucleotide polymorphism for species with molecular hyperdiversity. Mol Ecol. 2012;21:1345-59 pubmed publisher
    ..Inspired by molecular hyperdiversity in the nematode Caenorhabditis sp...
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