helminths

Summary

Summary: Commonly known as parasitic worms, this group includes the ACANTHOCEPHALA; NEMATODA; and PLATYHELMINTHS. Some authors consider certain species of LEECHES that can become temporarily parasitic as helminths.

Top Publications

  1. Santoro M, Mattiucci S, Kinsella J, Aznar F, Giordano D, Castagna F, et al. Helminth community structure of the Mediterranean gull (Ichthyaetus melanocephalus) in Southern Italy. J Parasitol. 2011;97:364-6 pubmed publisher
    ..Ten species of helminths, including 2 cestodes (Alcataenia larina and Tetrabothrius cylindraceus), 4 digeneans ( Aporchis massiliensis , ..
  2. Santoro M, Mattiucci S, Work T, Cimmaruta R, Nardi V, Cipriani P, et al. Parasitic infection by larval helminths in Antarctic fishes: pathological changes and impact on the host body condition index. Dis Aquat Organ. 2013;105:139-48 pubmed publisher
    ..Histologically, all fish showed varying severity of chronic inflammation associated with larval forms of helminths. Diphyllobothrideans and C. osculatum spp...
  3. Diawara A, Schwenkenbecher J, Kaplan R, Prichard R. Molecular and biological diagnostic tests for monitoring benzimidazole resistance in human soil-transmitted helminths. Am J Trop Med Hyg. 2013;88:1052-61 pubmed publisher
    In endemic countries with soil-transmitted helminths mass drug administration with albendazole or mebendazole are being implemented as a control strategy...
  4. Tilp C, Kapur V, Loging W, Erb K. Prerequisites for the pharmaceutical industry to develop and commercialise helminths and helminth-derived product therapy. Int J Parasitol. 2013;43:319-25 pubmed publisher
    ..In addition, many animal experiments have shown that certain helminths or products derived from helminths can protect mice from developing allergic or autoimmune disease...
  5. Gutman J, Emukah E, Okpala N, Okoro C, Obasi A, Miri E, et al. Effects of annual mass treatment with ivermectin for onchocerciasis on the prevalence of intestinal helminths. Am J Trop Med Hyg. 2010;83:534-41 pubmed publisher
    ..We conclude that benzimidazole MDA in IV treatment areas is indicated to effectively control hookworm. ..
  6. Cantacessi C, Gasser R. SCP/TAPS proteins in helminths--where to from now?. Mol Cell Probes. 2012;26:54-9 pubmed publisher
    ..Here, we review current knowledge of key SCP/TAPS proteins of helminths and their proposed roles in parasite-host interactions...
  7. Abdybekova A, Torgerson P. Frequency distributions of helminths of wolves in Kazakhstan. Vet Parasitol. 2012;184:348-51 pubmed publisher
    ..The wolves were sampled from an area of Kazakhstan where there is a high prevalence of hydatid cysts in livestock and where echinococcosis has been observed in wild ungulates. ..
  8. Albonico M, Ame S, Vercruysse J, Levecke B. Comparison of the Kato-Katz thick smear and McMaster egg counting techniques for monitoring drug efficacy against soil-transmitted helminths in schoolchildren on Pemba Island, Tanzania. Trans R Soc Trop Med Hyg. 2012;106:199-201 pubmed publisher
    ..The study revealed comparable drug efficacy results for both methods and confirmed the potency of the McMaster technique as an alternative method for monitoring large-scale deworming programmes...
  9. Leung J, Loke P. A role for IL-22 in the relationship between intestinal helminths, gut microbiota and mucosal immunity. Int J Parasitol. 2013;43:253-7 pubmed publisher
    ..We then consider the relationship between intestinal helminths and gut microbiota and hypothesize that this relationship may explain how helminths may improve symptoms of ..

More Information

Publications84

  1. Salgado Maldonado G, Caspeta Mandujano J, Moravec F, Soto Galera E, Rodiles Hernández R, Cabañas Carranza G, et al. Helminth parasites of freshwater fish in Chiapas, Mexico. Parasitol Res. 2011;108:31-59 pubmed publisher
    ..The taxonomic composition and distribution data reported here for the helminth fauna of Chiapas' freshwater fish, contribute to a better understanding of this faunal component in Central America. ..
  2. Hinney B, Wirtherle N, Kyule M, Miethe N, Zessin K, Clausen P. Prevalence of helminths in horses in the state of Brandenburg, Germany. Parasitol Res. 2011;108:1083-91 pubmed publisher
    The objective of the study was to estimate the prevalence of helminths in the horse population of the state of Brandenburg, Germany. One hundred and twenty-six horse farms in the state were selected by randomised stratified sampling...
  3. Koyasu S, Moro K, Tanabe M, Takeuchi T. Natural helper cells: a new player in the innate immune response against helminth infection. Adv Immunol. 2010;108:21-44 pubmed publisher
    ..immune response, characterized by the production of IL-4, IL-5, and IL-13, is a critical immune response against helminths invading cutaneous or mucosal sites...
  4. Fürst T, Müller I, Coulibaly J, Yao A, Utzinger J, N Goran E. Questionnaire-based approach to assess schoolchildren's physical fitness and its potential role in exploring the putative impact of helminth and Plasmodium spp. infections in Côte d'Ivoire. Parasit Vectors. 2011;4:116 pubmed publisher
    ..The previous practice of eliciting DWs by expert opinion has been challenged. More recent approaches employed quality of life (QoL) questionnaires to establish patient-based DWs, but results are ambiguous...
  5. Garrido Olvera L, Arita H, Pérez Ponce de León G. The influence of host ecology and biogeography on the helminth species richness of freshwater fishes in Mexico. Parasitology. 2012;139:1652-65 pubmed publisher
    Freshwater fish helminths, the most well known Mexican vertebrate parasites, include approximately 260 species (platyhelminthes, acanthocephalans, nematodes, and hirudineans)...
  6. Prichard R, Basáñez M, Boatin B, McCarthy J, García H, Yang G, et al. A research agenda for helminth diseases of humans: intervention for control and elimination. PLoS Negl Trop Dis. 2012;6:e1549 pubmed publisher
  7. Chammartin F, Scholte R, Guimaraes L, Tanner M, Utzinger J, Vounatsou P. Soil-transmitted helminth infection in South America: a systematic review and geostatistical meta-analysis. Lancet Infect Dis. 2013;13:507-18 pubmed publisher
    ..UBS Optimus Foundation and Brazilian Swiss Joint Research Programme (BSJRP 011008). ..
  8. Bourke C, Maizels R, Mutapi F. Acquired immune heterogeneity and its sources in human helminth infection. Parasitology. 2011;138:139-59 pubmed publisher
    Similarities in the immunobiology of different parasitic worm infections indicate that co-evolution of humans and helminths has shaped a common anti-helminth immune response...
  9. Todaro M, Kånneby T, Dal Zotto M, Jondelius U. Phylogeny of Thaumastodermatidae (Gastrotricha: Macrodasyida) inferred from nuclear and mitochondrial sequence data. PLoS ONE. 2011;6:e17892 pubmed publisher
  10. Ponlet N, Chaisiri K, Claude J, Morand S. Incorporating parasite systematics in comparative analyses of variation in spleen mass and testes sizes of rodents. Parasitology. 2011;138:1804-14 pubmed publisher
    ..traits potentially implicated in immune defence and in reproduction, using data on gastrointestinal helminths and their rodent hosts sampled in Southeast Asia...
  11. Maizels R, McSorley H, Smyth D. Helminths in the hygiene hypothesis: sooner or later?. Clin Exp Immunol. 2014;177:38-46 pubmed publisher
    ..However, the ability of helminths to dampen pathology in established inflammatory diseases implies that they can have therapeutic effects even if ..
  12. Boel M, Carrara V, Rijken M, Proux S, Nacher M, Pimanpanarak M, et al. Complex Interactions between soil-transmitted helminths and malaria in pregnant women on the Thai-Burmese border. PLoS Negl Trop Dis. 2010;4:e887 pubmed publisher
    ..We examined the association between geohelminths and malaria in pregnancy on the Thai-Burmese border...
  13. Schmidlin T, Hürlimann E, Silué K, Yapi R, Houngbedji C, Kouadio B, et al. Effects of hygiene and defecation behavior on helminths and intestinal protozoa infections in Taabo, Côte d'Ivoire. PLoS ONE. 2013;8:e65722 pubmed publisher
    More than 1 billion people are currently infected with soil-transmitted helminths and schistosomes. The global strategy to control helminthiases is the regular administration of anthelmintic drugs to at-risk populations...
  14. Molehin A, Gobert G, McManus D. Serine protease inhibitors of parasitic helminths. Parasitology. 2012;139:681-95 pubmed publisher
    ..A number of serpins have now been identified in parasitic helminths with putative involvement in immune regulation and in parasite survival through interference with the host ..
  15. Hussaarts L, van der Vlugt L, Yazdanbakhsh M, Smits H. Regulatory B-cell induction by helminths: implications for allergic disease. J Allergy Clin Immunol. 2011;128:733-9 pubmed publisher
    ..b>Helminths influence the host immune system by downregulating T-cell responses; the cytokine IL-10 appears to play a ..
  16. Benesh D, Chubb J, Parker G. Exploitation of the same trophic link favors convergence of larval life-history strategies in complex life cycle helminths. Evolution. 2011;65:2286-99 pubmed publisher
    ..We compiled data on the size and age at infectivity for trophically transmitted helminths (i.e., acanthocephalans, cestodes, and nematodes), and then categorized species into trophic links (e.g...
  17. Levecke B, Speybroeck N, Dobson R, Vercruysse J, Charlier J. Novel insights in the fecal egg count reduction test for monitoring drug efficacy against soil-transmitted helminths in large-scale treatment programs. PLoS Negl Trop Dis. 2011;5:e1427 pubmed publisher
    The fecal egg count reduction test (FECRT) is recommended to monitor drug efficacy against soil-transmitted helminths (STHs) in public health...
  18. Msyamboza K, Ngwira B, Banda R, Mkwanda S, Brabin B. Sentinel surveillance of lymphatic filariasis, schistosomiasis soil transmitted helminths and malaria in rural southern Malawi. Malawi Med J. 2010;22:12-4 pubmed
    ..Baseline prevalence and knowledge, attitude and perception (KAP) survey is a prerequisite for mass drug administration for the control of Lymphatic filariasis (LF) and other neglected tropical diseases...
  19. Monteiro C, Amato J, Amato S. Helminth parasitism in the Neotropical cormorant, Phalacrocorax brasilianus, in southern Brazil: effect of host size, weight, sex, and maturity state. Parasitol Res. 2011;109:849-55 pubmed publisher
    ..The present work records the richest helminth fauna for any bird of the genus Phalacrocorax and is the first study to evaluate the influence of length, weight, sex, and maturity state on parasitism...
  20. Zaccone P, Cooke A. Vaccine against autoimmune disease: can helminths or their products provide a therapy?. Curr Opin Immunol. 2013;25:418-23 pubmed publisher
    There is an increasing interest in exploiting the immunomodulatory effects of helminths and their products in treatment of diseases such as allergy, autoimmunity and inflammatory bowel disease...
  21. Foster N, Elsheikha H. The immune response to parasitic helminths of veterinary importance and its potential manipulation for future vaccine control strategies. Parasitol Res. 2012;110:1587-99 pubmed publisher
    Despite the increasing knowledge of the immunobiology and epidemiology of parasitic helminths of the gastrointestinal system and the cardiorespiratory system, complications arising from infections of animals and humans with these ..
  22. Chaisiri K, Chaeychomsri W, Siruntawineti J, Ribas A, Herbreteau V, Morand S. Diversity of gastrointestinal helminths among murid rodents from northern and northeastern Thailand. Southeast Asian J Trop Med Public Health. 2012;43:21-8 pubmed
    The presence of gastrointestinal helminths (GI helminths) was investigated among 725 murid rodents, trapped in various habitats of Nan, Loei and Buri Ram Provinces, Thailand...
  23. Hamid F, Wiria A, Wammes L, Kaisar M, Lell B, Ariawan I, et al. A longitudinal study of allergy and intestinal helminth infections in semi urban and rural areas of Flores, Indonesia (ImmunoSPIN Study). BMC Infect Dis. 2011;11:83 pubmed publisher
    ..The question of whether helminth infections play a role in allergic diseases can best be addressed by intervention studies. None of the studies so far have been based on a large scale placebo-controlled trial...
  24. Ayaz M, Raza M, Murtaza S, Akhtar S. Epidemiological survey of helminths of goats in southern Punjab, Pakistan. Trop Biomed. 2013;30:62-71 pubmed
    The main purpose of this study was to investigate the prevalence of helminths of goats such as Fasciola hepatica, Haemonchus contortus, Paramphistomum cervi, Oesophagostomum columbian, Cotylophoron cotylophorum, Monezia expansa, ..
  25. Webb E, Ekii A, Pala P. Epidemiology and immunology of helminth-HIV interactions. Curr Opin HIV AIDS. 2012;7:245-53 pubmed publisher
    b>Helminths and HIV-1 use multiple mechanisms to avoid or deviate immune responses, and these mechanisms may interact with important consequences for the epidemiology of each infection...
  26. Qadir S, Dixit A, Dixit P, Sharma R. Intestinal helminths induce haematological changes in dogs from Jabalpur, India. J Helminthol. 2011;85:401-3 pubmed publisher
    The effect of canine intestinal helminths on the haematological profile of 200 dogs, of both sexes and variable age, visiting university veterinary clinics for routine examination was investigated...
  27. Vercruysse J, Levecke B, Prichard R. Human soil-transmitted helminths: implications of mass drug administration. Curr Opin Infect Dis. 2012;25:703-8 pubmed publisher
    ..In this review, we discuss the practical implications of MDA programs on the development of anthelmintic resistance in human soil-transmitted helminths (STH).
  28. Neill D, McKenzie A. Nuocytes and beyond: new insights into helminth expulsion. Trends Parasitol. 2011;27:214-21 pubmed publisher
    ..It also affords us the opportunity to highlight the diversity of immune responses that can be driven by innate cells responding rapidly to early cytokine cues...
  29. Allen J, Maizels R. Diversity and dialogue in immunity to helminths. Nat Rev Immunol. 2011;11:375-88 pubmed publisher
    ..Finally, we more broadly consider how these immunological players are blended and regulated in order to accommodate persistent infection or to mount a vigorous protective response and achieve sterile immunity...
  30. Otranto D, Eberhard M. Zoonotic helminths affecting the human eye. Parasit Vectors. 2011;4:41 pubmed publisher
    ..Importantly, zoonotic helminths that affect human eyes (HIE) may cause blindness with severe socio-economic consequences to human communities...
  31. Poulin R, Leung T. Latitudinal gradient in the taxonomic composition of parasite communities. J Helminthol. 2011;85:228-33 pubmed publisher
  32. Violante González J, Monks S, Gil Guerrero S, Rojas Herrera A, Flores Garza R, Larumbe Morán E. Parasite communities of the neotropical cormorant Phalacrocorax brasilianus (Gmelin) (Aves, Phalacrocoracidae) from two coastal lagoons in Guerrero state, Mexico. Parasitol Res. 2011;109:1303-9 pubmed publisher
    ..Fourteen species of adult helminths (6,391 individuals) from 48 cormorants were identified: 9 digeneans, 1 acanthocephalan, 1 cestode, and 3 ..
  33. Bwalya E, Nalubamba K, Hankanga C, Namangala B. Prevalence of canine gastrointestinal helminths in urban Lusaka and rural Katete Districts of Zambia. Prev Vet Med. 2011;100:252-5 pubmed publisher
    ..were collected from January 2010 through September 2010 to determine the prevalence of gastrointestinal (GI) helminths infestation in dogs in urban Lusaka and rural Katete Districts of Zambia...
  34. Dalzell J, Warnock N, McVeigh P, Marks N, Mousley A, Atkinson L, et al. Considering RNAi experimental design in parasitic helminths. Parasitology. 2012;139:589-604 pubmed publisher
    ..An appraisal of current practices, trends and ideals of RNAi experimental design in parasitic helminths is both timely and necessary for a number of reasons: firstly, the increasing availability of parasitic helminth ..
  35. McSorley H, Hewitson J, Maizels R. Immunomodulation by helminth parasites: defining mechanisms and mediators. Int J Parasitol. 2013;43:301-10 pubmed publisher
    ..Here, we review the immunological pathways that helminths exploit to downregulate immune responses, both against bystander specificities such as allergens and against ..
  36. Ben Ami Shor D, Harel M, Eliakim R, Shoenfeld Y. The hygiene theory harnessing helminths and their ova to treat autoimmunity. Clin Rev Allergy Immunol. 2013;45:211-6 pubmed publisher
    ..There is an ongoing debate whether infection prevents or precipitates autoimmune diseases. Various helminths species used in several animal models were shown to limit inflammatory activity in a variety of diseases ..
  37. Marks N, Maule A. Neuropeptides in helminths: occurrence and distribution. Adv Exp Med Biol. 2010;692:49-77 pubmed
    ..targets for chemotherapeutic-based control strategies, they do highlight the signaling systems present in these helminths and provide tools for the discovery of more amenable targets such as neuropeptide receptors or neuropeptide ..
  38. Maizels R, Hewitson J, Smith K. Susceptibility and immunity to helminth parasites. Curr Opin Immunol. 2012;24:459-66 pubmed publisher
  39. Santoro M, Kinsella J, Galiero G, degli Uberti B, Aznar F. Helminth community structure in birds of prey (Accipitriformes and Falconiformes) in southern Italy. J Parasitol. 2012;98:22-9 pubmed publisher
    ..We conclude that in the Calabria region of southern Italy, each of the raptor species studied is distinct in terms of its helminth communities, and more diverse feeding habits of the host correspond with richer helminth communities...
  40. Harris N, Gause W. To B or not to B: B cells and the Th2-type immune response to helminths. Trends Immunol. 2011;32:80-8 pubmed publisher
    ..B cells are increasingly recognized as important during the Th2-type immune response to helminths, and B cell activation might be a target for effective vaccine development...
  41. Hepworth M, Daniłowicz Luebert E, Rausch S, Metz M, Klotz C, Maurer M, et al. Mast cells orchestrate type 2 immunity to helminths through regulation of tissue-derived cytokines. Proc Natl Acad Sci U S A. 2012;109:6644-9 pubmed publisher
    ..and type 2 cytokine production and harbored increased parasite burdens following infection with gastrointestinal helminths (Heligmosomoides polygyrus bakeri and Trichuris muris)...
  42. van der Vlugt L, Labuda L, Ozir Fazalalikhan A, Lievers E, Gloudemans A, Liu K, et al. Schistosomes induce regulatory features in human and mouse CD1d(hi) B cells: inhibition of allergic inflammation by IL-10 and regulatory T cells. PLoS ONE. 2012;7:e30883 pubmed publisher
  43. Magalhães R, Clements A, Patil A, Gething P, Brooker S. The applications of model-based geostatistics in helminth epidemiology and control. Adv Parasitol. 2011;74:267-96 pubmed publisher
  44. Acka C, Raso G, N Goran E, Tschannen A, Bogoch I, Séraphin E, et al. Parasitic worms: knowledge, attitudes, and practices in Western Côte d'Ivoire with implications for integrated control. PLoS Negl Trop Dis. 2010;4:e910 pubmed publisher
    ..However, local knowledge, attitudes, and practices (KAP) of parasitic worms are poorly understood, although such information is required for prevention and sustainable control...
  45. Elliott D, Weinstock J. Helminth-host immunological interactions: prevention and control of immune-mediated diseases. Ann N Y Acad Sci. 2012;1247:83-96 pubmed publisher
    Exposure to commensal and pathogenic organisms strongly influences our immune system. Exposure to helminths was frequent before humans constructed their current highly hygienic environment...
  46. Ahmed A, Al Mekhlafi H, Choy S, Ithoi I, Al Adhroey A, Abdulsalam A, et al. The burden of moderate-to-heavy soil-transmitted helminth infections among rural malaysian aborigines: an urgent need for an integrated control programme. Parasit Vectors. 2011;4:242 pubmed publisher
    ..Soil-transmitted helminth (STH) infections, among the most common neglected tropical diseases, continue to be a major threat to the health and socioeconomic wellbeing of infected people especially children in developing countries...
  47. Hübner M, Layland L, Hoerauf A. Helminths and their implication in sepsis - a new branch of their immunomodulatory behaviour?. Pathog Dis. 2013;69:127-41 pubmed publisher
    ..multiple epidemiological studies and animal models have characterized the protective immune responses induced by helminths during auto-inflammatory disorders...
  48. Fleming J. Helminth therapy and multiple sclerosis. Int J Parasitol. 2013;43:259-74 pubmed publisher
    ..b>Helminths have been shown to augment immunoregulation...
  49. Bath J, Eneh P, Bakken A, Knox M, Schiedt M, Campbell J. The impact of perception and knowledge on the treatment and prevention of intestinal worms in the Manikganj district of Bangladesh. Yale J Biol Med. 2010;83:171-84 pubmed
    Soil transmitted helminths (STHs) affect more than one billion of the world's population and are very prevalent in regions with high poverty rates and poor sanitation...
  50. Blackwell A, Gurven M, Sugiyama L, Madimenos F, Liebert M, Martin M, et al. Evidence for a peak shift in a humoral response to helminths: age profiles of IgE in the Shuar of Ecuador, the Tsimane of Bolivia, and the U.S. NHANES. PLoS Negl Trop Dis. 2011;5:e1218 pubmed publisher
    ..Although studies have noted peak shifts in helminths, corresponding peak shifts in total IgE have not been investigated, nor has the age-patterning been carefully ..
  51. White R, Artavanis Tsakonas K. How helminths use excretory secretory fractions to modulate dendritic cells. Virulence. 2012;3:668-77 pubmed publisher
    ..Herein, we will review the effects of helminth excretory-secretory fractions on dendritic cells and discuss how this interaction is crucial in shaping the host response...
  52. Jex A, Lim Y, Bethony J, Hotez P, Young N, Gasser R. Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Adv Parasitol. 2011;74:231-65 pubmed publisher
    Soil-transmitted helminths (STHs) pose significant public health challenges in many countries of Southeast Asia (SEA)...
  53. Koroma J, Peterson J, Gbakima A, Nylander F, Sahr F, Soares Magalhaes R, et al. Geographical distribution of intestinal schistosomiasis and soil-transmitted helminthiasis and preventive chemotherapy strategies in Sierra Leone. PLoS Negl Trop Dis. 2010;4:e891 pubmed publisher
  54. Zaccone P, Cooke A. Helminth mediated modulation of Type 1 diabetes (T1D). Int J Parasitol. 2013;43:311-8 pubmed publisher
    ..sanitation and public health measures have altered our interactions with certain infectious agents such as helminths. There is increasing interest in the use of helminths or their products to alleviate inflammatory or allergic ..
  55. Salgado Maldonado G, Quiroz Martínez B. Taxonomic composition and endemism of the helminth fauna of freshwater fishes of Mexico. Parasitol Res. 2013;112:1-18 pubmed publisher
    ..Current data suggests a 22 % (37/170) endemism amongst helminths of freshwater fishes of Mexico...
  56. Jeandron A, Abdyldaieva G, Usubalieva J, Ensink J, Cox J, Matthys B, et al. Accuracy of the Kato-Katz, adhesive tape and FLOTAC techniques for helminth diagnosis among children in Kyrgyzstan. Acta Trop. 2010;116:185-92 pubmed publisher
    ..dendriticum. Overall results suggest that, although FLOTAC represents a promising technique for helminth diagnosis in Kyrgyzstan, the repeated adhesive tape test remains so far the method of choice for diagnosing E. vermicularis...
  57. Wiria A, Djuardi Y, Supali T, Sartono E, Yazdanbakhsh M. Helminth infection in populations undergoing epidemiological transition: a friend or foe?. Semin Immunopathol. 2012;34:889-901 pubmed publisher
    ..Furthermore, we address the issue of decreasing helminth infections in many parts of the world within the context of increasing inflammatory, metabolic, and cardiovascular diseases...
  58. Mizgajska Wiktor H, Jarosz W, Piłacińska B, Dziemian S. [Helminths of hedgehogs, Erinaceus europaeus and E. roumanicus from Pozna? region, Poland--coprological study]. Wiad Parazytol. 2010;56:329-32 pubmed
    ..roumanicus. In both sexes the majority of infections were of low intensity, high intensity infections occurring only sporadically. No zoonotic species of endoparasites were recorded in these samples...
  59. Daniłowicz Luebert E, O Regan N, Steinfelder S, Hartmann S. Modulation of specific and allergy-related immune responses by helminths. J Biomed Biotechnol. 2011;2011:821578 pubmed publisher
    b>Helminths are master regulators of host immune responses utilising complex mechanisms to dampen host protective Th2-type responses and favour long-term persistence...
  60. Voehringer D. Basophils in immune responses against helminths. Microbes Infect. 2011;13:881-7 pubmed publisher
    ..Based on recent reports, this review discusses potential roles of basophils and other cells during early and late phases of the immune response against parasitic worms...
  61. Weinstock J, Elliott D. Translatability of helminth therapy in inflammatory bowel diseases. Int J Parasitol. 2013;43:245-51 pubmed publisher
    ..Meticulous hygiene interrupts conduits of transmission required for ubiquitous exposure to parasitic worms (helminths). We proposed that loss of exposure to helminths permits development of IBD...
  62. Fürst T, Silué K, Ouattara M, N Goran D, Adiossan L, N Guessan Y, et al. Schistosomiasis, soil-transmitted helminthiasis, and sociodemographic factors influence quality of life of adults in Côte d'Ivoire. PLoS Negl Trop Dis. 2012;6:e1855 pubmed publisher
    ..However, disability weights, which capture the disability incurred by a typical patient of a certain condition, are fundamental to such burden calculation and their determination remains a widely debated issue...
  63. Traoré S, Odermatt P, Bonfoh B, Utzinger J, Aka N, Adoubryn K, et al. No Paragonimus in high-risk groups in Côte d'Ivoire, but considerable prevalence of helminths and intestinal protozoon infections. Parasit Vectors. 2011;4:96 pubmed publisher
    ..The disease is often confused with tuberculosis. Paragonimiasis is thought to be endemic in south-western Côte d'Ivoire...
  64. Degarege A, Legesse M, Medhin G, Animut A, Erko B. Malaria and related outcomes in patients with intestinal helminths: a cross-sectional study. BMC Infect Dis. 2012;12:291 pubmed publisher
    The effects of helminth co-infection on malaria in humans remain uncertain. This study aimed to evaluate the nature of association of intestinal helminths with prevalence and clinical outcomes of Plasmodium infection.
  65. Hagen J, Lee E, Fairlie W, Kalinna B. Functional genomics approaches in parasitic helminths. Parasite Immunol. 2012;34:163-82 pubmed publisher
    As research on parasitic helminths is moving into the post-genomic era, an enormous effort is directed towards deciphering gene function and to achieve gene annotation...
  66. Hwang Y, McKenzie A. Innate lymphoid cells in immunity and disease. Adv Exp Med Biol. 2013;785:9-26 pubmed publisher
    ..However, the dysregulation of ILCs has been implicated in autoimmune and inflammatory diseases. Here, we will review the recent advances in ILC development and their roles in immunity and disease, with a primary focus on type 2 ILCs...
  67. Beech R, Skuce P, Bartley D, Martin R, Prichard R, Gilleard J. Anthelmintic resistance: markers for resistance, or susceptibility?. Parasitology. 2011;138:160-74 pubmed publisher
    ..Resistance may result from a loss of sensitivity as well as the appearance of resistance. A focus on the presence of anthelmintic susceptibility may be as important as the detection of resistance...
  68. Mousley A, Novozhilova E, Kimber M, Day T. Neuropeptide physiology in helminths. Adv Exp Med Biol. 2010;692:78-97 pubmed
    ..evidence demonstrating that neuropeptides play critical roles in the biology of both free-living and parasitic helminths. While it is certainly true that there remains a great deal to learn about the biology of neuropeptides in both ..
  69. Steinmann P, Utzinger J, Du Z, Jiang J, Chen J, Hattendorf J, et al. Efficacy of single-dose and triple-dose albendazole and mebendazole against soil-transmitted helminths and Taenia spp.: a randomized controlled trial. PLoS ONE. 2011;6:e25003 pubmed publisher
    ..We compared the efficacy of single-dose versus triple-dose treatment against hookworm and other STHs in a community-based randomized controlled trial in the People's Republic of China...
  70. Sun S, Wang X, Wu X, Zhao Y, Wang F, Liu X, et al. Toll-like receptor activation by helminths or helminth products to alleviate inflammatory bowel disease. Parasit Vectors. 2011;4:186 pubmed publisher
    ..Thus, the use of antagonists of TLR-signaling and agonists of their negative regulators from helminths or helminth products should be considered for the treatment of IBD.
  71. Hoste H, Torres Acosta J. Non chemical control of helminths in ruminants: adapting solutions for changing worms in a changing world. Vet Parasitol. 2011;180:144-54 pubmed publisher
    ..This new era of GIN management requires a new paradigm: to achieve enough control to reduce the negative impact of GIN infections enabling an optimum level of production, health and welfare...
  72. Soares Magalhaes R, Biritwum N, Gyapong J, Brooker S, Zhang Y, Blair L, et al. Mapping helminth co-infection and co-intensity: geostatistical prediction in ghana. PLoS Negl Trop Dis. 2011;5:e1200 pubmed publisher
    ..haematobium and hookworm infection, plus the spatial overlap of infection intensity of both parasites, in Ghana. The aim was to produce maps to assist the planning and evaluation of national parasitic disease control programs...
  73. Matthys B, Bobieva M, Karimova G, Mengliboeva Z, Jean Richard V, Hoimnazarova M, et al. Prevalence and risk factors of helminths and intestinal protozoa infections among children from primary schools in western Tajikistan. Parasit Vectors. 2011;4:195 pubmed publisher
    ..The present study aimed at assessing the extent of helminths and intestinal protozoa infections among children of 10 schools in four districts of Tajikistan, and to make ..
  74. Bružinskaitė Schmidhalter R, Sarkūnas M, Malakauskas A, Mathis A, Torgerson P, Deplazes P. Helminths of red foxes (Vulpes vulpes) and raccoon dogs (Nyctereutes procyonoides) in Lithuania. Parasitology. 2012;139:120-7 pubmed publisher
    Red foxes and raccoon dogs are hosts for a wide range of parasites including important zoonotic helminths. The raccoon dog has recently invaded into Europe from the east...
  75. Hodges M, Dada N, Wamsley A, Paye J, Nyorkor E, Sonnie M, et al. Improved mapping strategy to better inform policy on the control of schistosomiasis and soil-transmitted helminthiasis in Sierra Leone. Parasit Vectors. 2011;4:97 pubmed publisher
    ..Fifty-nine chiefdoms and one school in every chiefdom were selected. Thirty school children aged 9-14 years from each school (total: 1760) were examined by parasitological methods for infection with Schistosoma mansoni and STHs...