strongylocentrotus purpuratus

Summary

Summary: A species of SEA URCHINS in the family Strongylocentrotidae found on the Pacific coastline from Alaska to Mexico. This species serves as a major research model for molecular developmental biology and other fields.

Top Publications

  1. Kelly M, Padilla Gamiño J, Hofmann G. Natural variation and the capacity to adapt to ocean acidification in the keystone sea urchin Strongylocentrotus purpuratus. Glob Chang Biol. 2013;19:2536-46 pubmed publisher
    ..Here, we measure the capacity of the ecologically important purple sea urchin Strongylocentrotus purpuratus to adapt to OA, using a breeding experiment to estimate additive genetic variance for larval size (an ..
  2. Buckley K, Munshaw S, Kepler T, Smith L. The 185/333 gene family is a rapidly diversifying host-defense gene cluster in the purple sea urchin Strongylocentrotus purpuratus. J Mol Biol. 2008;379:912-28 pubmed publisher
    ..These results add to the growing body of evidence suggesting that invertebrate immune systems are not simple and static, but are dynamic and highly complex, and may employ group-specific mechanisms for diversification...
  3. Balhoff J, Wray G. Evolutionary analysis of the well characterized endo16 promoter reveals substantial variation within functional sites. Proc Natl Acad Sci U S A. 2005;102:8591-6 pubmed publisher
  4. Foe V, Von Dassow G. Stable and dynamic microtubules coordinately shape the myosin activation zone during cytokinetic furrow formation. J Cell Biol. 2008;183:457-70 pubmed publisher
    ..We conclude that opposite effects of stable versus dynamic microtubules focuses myosin activation to the cell equator during cytokinesis...
  5. Odell G, Foe V. An agent-based model contrasts opposite effects of dynamic and stable microtubules on cleavage furrow positioning. J Cell Biol. 2008;183:471-83 pubmed publisher
    ..Because stabilized microtubules aim statistically at the equatorial spindle midplane, that is where centralspindlin accumulates to stimulate furrow formation...
  6. Cameron R, Samanta M, Yuan A, He D, Davidson E. SpBase: the sea urchin genome database and web site. Nucleic Acids Res. 2009;37:D750-4 pubmed publisher
    ..served from the databases emerges from the draft genomic sequence of the purple sea urchin, Strongylocentrotus purpuratus and includes sequence data and genomic resource descriptions for other members of the echinoderm clade ..
  7. Buckley K, Smith L. Extraordinary diversity among members of the large gene family, 185/333, from the purple sea urchin, Strongylocentrotus purpuratus. BMC Mol Biol. 2007;8:68 pubmed publisher
    ..The diversity of the 185/333 gene family represents an intriguing addition to what is known about the S. purpuratus immune response, and provides further evidence that invertebrate immune systems are neither simple nor static...
  8. Wei Z, Yaguchi J, Yaguchi S, Angerer R, Angerer L. The sea urchin animal pole domain is a Six3-dependent neurogenic patterning center. Development. 2009;136:1179-89 pubmed publisher
  9. Todgham A, Hofmann G. Transcriptomic response of sea urchin larvae Strongylocentrotus purpuratus to CO2-driven seawater acidification. J Exp Biol. 2009;212:2579-94 pubmed publisher
    ..of the physiological response of larvae of a calcifying marine invertebrate, the purple sea urchin, Strongylocentrotus purpuratus, to CO(2)-driven seawater acidification...

More Information

Publications79

  1. Yaguchi S, Yaguchi J, Burke R. Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos. Development. 2006;133:2337-46 pubmed
    ..Like other metazoans, echinoderms appear to have a phase of neural development during which the specification of ectoderm restricts and patterns neurogenesis...
  2. Davidson E. The sea urchin genome: where will it lead us?. Science. 2006;314:939-40 pubmed
    ..The sequence will accelerate progress toward complete understanding of the genomic regulatory system that controls developmental specification and morphogenetic function, thus illuminating basic developmental process in all animals...
  3. Ruas M, Rietdorf K, Arredouani A, Davis L, Lloyd Evans E, Koegel H, et al. Purified TPC isoforms form NAADP receptors with distinct roles for Ca(2+) signaling and endolysosomal trafficking. Curr Biol. 2010;20:703-9 pubmed publisher
    ..We propose that NAADP regulates endolysosomal Ca(2+) storage and release via TPCs and coordinates endoplasmic reticulum Ca(2+) release in a role that impacts on Ca(2+) signaling in health and disease [6]...
  4. Oliveri P, Tu Q, Davidson E. Global regulatory logic for specification of an embryonic cell lineage. Proc Natl Acad Sci U S A. 2008;105:5955-62 pubmed publisher
    ..The GRN precisely predicts gene expression responses and provides a coherent explanation of the biology of specification...
  5. Levitan D, Stapper A. Simultaneous positive and negative frequency-dependent selection on sperm bindin, a gamete recognition protein in the sea urchin Strongylocentrotus purpuratus. Evolution. 2010;64:785-97 pubmed publisher
    ..We explored how variation in sperm bindin influences reproductive success of the sea urchin Strongylocentrotus purpuratus during group spawning in the sea...
  6. Ghosh J, Buckley K, Nair S, Raftos D, Miller C, Majeske A, et al. Sp185/333: a novel family of genes and proteins involved in the purple sea urchin immune response. Dev Comp Immunol. 2010;34:235-45 pubmed publisher
    ..system of genes, messages and proteins are expressed in the coelomocytes of the purple sea urchin, Strongylocentrotus purpuratus, and is an extraordinary example of diversification of a putative innate immune response system in an ..
  7. Rast J, Smith L, Loza Coll M, Hibino T, Litman G. Genomic insights into the immune system of the sea urchin. Science. 2006;314:952-6 pubmed
    ..The findings serve to underscore the dynamic utilization of receptors and the complexity of immune recognition that may be basal for deuterostomes and predicts features of the ancestral bilaterian form...
  8. Hernandez J, Russell M. Substratum cavities affect growth-plasticity, allometry, movement and feeding rates in the sea urchin Strongylocentrotus purpuratus. J Exp Biol. 2010;213:520-5 pubmed publisher
    ..the influence of rock cavities, or pits, on the growth dynamics and behavior of the purple sea urchin, Strongylocentrotus purpuratus. In a paired-designed, laboratory experiment, sea urchins were assigned to sandstone blocks that were ..
  9. Stevens M, Dhillon J, Miller C, Messier Solek C, Majeske A, Zuelke D, et al. SpTie1/2 is expressed in coelomocytes, axial organ and embryos of the sea urchin Strongylocentrotus purpuratus, and is an orthologue of vertebrate Tie1 and Tie2. Dev Comp Immunol. 2010;34:884-95 pubmed publisher
    ..We speculate that SpTie1/2 may be involved in the proliferation of sea urchin immune cells in both adults and embryos...
  10. Terwilliger D, Buckley K, Mehta D, Moorjani P, Smith L. Unexpected diversity displayed in cDNAs expressed by the immune cells of the purple sea urchin, Strongylocentrotus purpuratus. Physiol Genomics. 2006;26:134-44 pubmed
    ..Two 185/333 genes, identified in the partially assembled Strongylocentrotus purpuratus genome, have two exons...
  11. Amador Cano G, Carpizo Ituarte E, Cristino Jorge D. Role of protein kinase C, G-protein coupled receptors, and calcium flux during metamorphosis of the sea urchin Strongylocentrotus purpuratus. Biol Bull. 2006;210:121-31 pubmed
    ..In addition, according to the results obtained with G-protein inhibitors, the GPCRs may be shared between the artificial (KCl) and natural (biofilm) inducers...
  12. Tu Q, Cameron R, Worley K, Gibbs R, Davidson E. Gene structure in the sea urchin Strongylocentrotus purpuratus based on transcriptome analysis. Genome Res. 2012;22:2079-87 pubmed publisher
    A comprehensive transcriptome analysis has been performed on protein-coding RNAs of Strongylocentrotus purpuratus, including 10 different embryonic stages, six feeding larval and metamorphosed juvenile stages, and six adult tissues...
  13. Hammond L, Hofmann G. Early developmental gene regulation in Strongylocentrotus purpuratus embryos in response to elevated CO? seawater conditions. J Exp Biol. 2012;215:2445-54 pubmed publisher
    ..and the initiation of spiculogenesis, two crucial developmental processes in the purple sea urchin, Strongylocentrotus purpuratus. Embryos were reared at the current, accepted oceanic CO(2) concentration of 380 microatmospheres (?..
  14. Bement W, Benink H, Von Dassow G. A microtubule-dependent zone of active RhoA during cleavage plane specification. J Cell Biol. 2005;170:91-101 pubmed
    ..We conclude that microtubules specify the cytokinetic apparatus via a dynamic zone of local RhoA activity...
  15. Terwilliger D, Clow L, Gross P, Smith L. Constitutive expression and alternative splicing of the exons encoding SCRs in Sp152, the sea urchin homologue of complement factor B. Implications on the evolution of the Bf/C2 gene family. Immunogenetics. 2004;56:531-43 pubmed
    The purple sea urchin, Strongylocentrotus purpuratus, possesses a non-adaptive immune system including elements homologous to C3 and factor B (Bf) of the vertebrate complement system...
  16. Lee P, Davidson E. Expression of Spgatae, the Strongylocentrotus purpuratus ortholog of vertebrate GATA4/5/6 factors. Gene Expr Patterns. 2004;5:161-5 pubmed publisher
    ..Towards the end of embryogenesis, expression in the hindgut decreases. The terminal pattern of expression is in midgut plus coelomic pouches...
  17. Yerramilli D, Johnsen S. Spatial vision in the purple sea urchin Strongylocentrotus purpuratus (Echinoidea). J Exp Biol. 2010;213:249-55 pubmed publisher
    ..acuity that appears to be mediated by their spines screening off-axis light suggests that the urchin Strongylocentrotus purpuratus, with its higher spine density, may have even more acute spatial vision...
  18. Pespeni M, Garfield D, Manier M, Palumbi S. Genome-wide polymorphisms show unexpected targets of natural selection. Proc Biol Sci. 2012;279:1412-20 pubmed publisher
    ..we performed one of the first genome-wide surveys in a marine species, comparing purple sea urchins, Strongylocentrotus purpuratus, from two distant locations along the species' wide latitudinal range...
  19. Place S, Smith B. Effects of seawater acidification on cell cycle control mechanisms in Strongylocentrotus purpuratus embryos. PLoS ONE. 2012;7:e34068 pubmed publisher
    ..We grew embryos of the purple sea urchin, Strongylocentrotus purpuratus, in seawater artifically buffered to a pH of ?7.0, 7.5, and 8.0 by CO(2) infusion...
  20. Rast J, Messier Solek C. Marine invertebrate genome sequences and our evolving understanding of animal immunity. Biol Bull. 2008;214:274-83 pubmed
    ..In this review we summarize these findings with particular attention toward immunity in Strongylocentrotus purpuratus, the purple sea urchin, and outline the changing perspective on the evolution of deuterostome immunity.
  21. Runcie D, Garfield D, Babbitt C, Wygoda J, Mukherjee S, Wray G. Genetics of gene expression responses to temperature stress in a sea urchin gene network. Mol Ecol. 2012;21:4547-62 pubmed publisher
    ..of additive genetic variation to gene expression during development of the purple sea urchin, Strongylocentrotus purpuratus, under increased temperatures that model realistic climate change scenarios...
  22. Hamdoun A, Cherr G, Roepke T, Epel D. Activation of multidrug efflux transporter activity at fertilization in sea urchin embryos (Strongylocentrotus purpuratus). Dev Biol. 2004;276:452-62 pubmed
    ..In addition, inhibition of mrp activity with MK571 alone retards mitosis indicating that mrp-like activity may also be required for early cell divisions...
  23. Brockton V, Henson J, Raftos D, Majeske A, Kim Y, Smith L. Localization and diversity of 185/333 proteins from the purple sea urchin--unexpected protein-size range and protein expression in a new coelomocyte type. J Cell Sci. 2008;121:339-48 pubmed publisher
    ..The diversity of the 185/333 proteins, their expression in response to immune challenge, and their cellular localization suggests this protein family and the small phagocytes have an important immunological role in the sea urchin...
  24. Wood C, Nishigaki T, Furuta T, Baba S, Darszon A. Real-time analysis of the role of Ca(2+) in flagellar movement and motility in single sea urchin sperm. J Cell Biol. 2005;169:725-31 pubmed
    ..Instead we propose a new model whereby flagella bending is increased by Ca(2+) flux through the nimodipine-sensitive pathway, and is unaffected by [Ca(2+)]i increases through alternative pathways...
  25. Fugmann S, Messier C, Novack L, Cameron R, Rast J. An ancient evolutionary origin of the Rag1/2 gene locus. Proc Natl Acad Sci U S A. 2006;103:3728-33 pubmed
    ..a closely linked pair of genes, SpRag1L and SpRag2L, from an invertebrate, the purple sea urchin (Strongylocentrotus purpuratus) with similarity in both sequence and genomic organization to the vertebrate Rag1 and Rag2 genes...
  26. Sodergren E, Weinstock G, Davidson E, Cameron R, Gibbs R, Angerer R, et al. The genome of the sea urchin Strongylocentrotus purpuratus. Science. 2006;314:941-52 pubmed
    We report the sequence and analysis of the 814-megabase genome of the sea urchin Strongylocentrotus purpuratus, a model for developmental and systems biology...
  27. Davis L, Morgan A, Ruas M, Wong J, Graeff R, Poustka A, et al. Ca(2+) signaling occurs via second messenger release from intraorganelle synthesis sites. Curr Biol. 2008;18:1612-8 pubmed publisher
    ..This represents a novel signaling mechanism whereby an extracellular stimulus increases the concentration of a second messenger by promoting messenger transport from intraorganelle synthesis sites to the cytosol...
  28. Aguilera L, Galindo B, S nchez D, Santill n M. What is the core oscillator in the speract-activated pathway of the Strongylocentrotus purpuratus sperm flagellum?. Biophys J. 2012;102:2481-8 pubmed publisher
    ..from a mathematical modeling perspective, that the reported speract-activated signaling pathway in Strongylocentrotus purpuratus (speract being a sperm-activating peptide specific to this species) has the necessary elements to ..
  29. Minokawa T, Wikramanayake A, Davidson E. cis-Regulatory inputs of the wnt8 gene in the sea urchin endomesoderm network. Dev Biol. 2005;288:545-58 pubmed
    ..Here, the modular cis-regulatory system of the wnt8 gene of Strongylocentrotus purpuratus was characterized functionally, and shown to respond to blockade of both Blimp1/Krox and Tcf1/beta-..
  30. Loram J, Bodnar A. Age-related changes in gene expression in tissues of the sea urchin Strongylocentrotus purpuratus. Mech Ageing Dev. 2012;133:338-47 pubmed publisher
    ..gene expression were examined in three tissues (muscle, esophagus and nerve) of the sea urchin species Strongylocentrotus purpuratus. The results indicate age-related changes in gene expression involving many key cellular functions ..
  31. Rowe M, Elphick M. Discovery of a second SALMFamide gene in the sea urchin Strongylocentrotus purpuratus reveals that L-type and F-type SALMFamide neuropeptides coexist in an echinoderm species. Mar Genomics. 2010;3:91-7 pubmed publisher
    ..Here we have obtained a new insight on this issue with the discovery that in the sea urchin Strongylocentrotus purpuratus there are two SALMFamide genes...
  32. Dheilly N, Nair S, Smith L, Raftos D. Highly variable immune-response proteins (185/333) from the sea urchin, Strongylocentrotus purpuratus: proteomic analysis identifies diversity within and between individuals. J Immunol. 2009;182:2203-12 pubmed publisher
    185/333 genes and transcripts from the purple sea urchin, Strongylocentrotus purpuratus, predict high levels of amino acid diversity within the encoded proteins...
  33. Oliver T, Garfield D, Manier M, Haygood R, Wray G, Palumbi S. Whole-genome positive selection and habitat-driven evolution in a shallow and a deep-sea urchin. Genome Biol Evol. 2010;2:800-14 pubmed publisher
    ..and stage-specific gene expression in two closely-related sea urchins, the shallow-water Strongylocentrotus purpuratus and the deep-sea Allocentrotus fragilis, which have diverged greatly in their adult but not larval ..
  34. Pespeni M, Oliver T, Manier M, Palumbi S. Restriction Site Tiling Analysis: accurate discovery and quantitative genotyping of genome-wide polymorphisms using nucleotide arrays. Genome Biol. 2010;11:R44 pubmed publisher
    ..It is highly accurate and free from ascertainment bias. We apply the approach to uncover genomic differentiation in the purple sea urchin...
  35. Calestani C, Rogers D. Cis-regulatory analysis of the sea urchin pigment cell gene polyketide synthase. Dev Biol. 2010;340:249-55 pubmed publisher
    The Strongylocentrotus purpuratus polyketide synthase gene (SpPks) encodes an enzyme required for the biosynthesis of the larval pigment echinochrome...
  36. Walters J, Binkley E, Haygood R, Romano L. Evolutionary analysis of the cis-regulatory region of the spicule matrix gene SM50 in strongylocentrotid sea urchins. Dev Biol. 2008;315:567-78 pubmed publisher
    ..of SM50, which has already been characterized to a considerable extent in the purple sea urchin, Strongylocentrotus purpuratus. We have isolated the cis-regulatory region from 15 individuals of S...
  37. Dheilly N, Raftos D, Haynes P, Smith L, Nair S. Shotgun proteomics of coelomic fluid from the purple sea urchin, Strongylocentrotus purpuratus. Dev Comp Immunol. 2013;40:35-50 pubmed publisher
    ..However, based on this dataset, the expression of TLRs, NLRs and fibrinogen domain containing proteins in coelomic fluid and coelomocytes could not be verified...
  38. Smith M, Cruz Smith L, Cameron R, Urry L. The larval stages of the sea urchin, Strongylocentrotus purpuratus. J Morphol. 2008;269:713-33 pubmed publisher
    The adult body plan of Strongylocentrotus purpuratus is established within the imaginal rudiment during the larval stages...
  39. Galindo B, de la Vega Beltr n J, Labarca P, Vacquier V, Darszon A. Sp-tetraKCNG: A novel cyclic nucleotide gated K(+) channel. Biochem Biophys Res Commun. 2007;354:668-75 pubmed publisher
    ..cGMP-regulated, tetrameric, K(+) selective channel (Sp-tetraKCNG) was discovered in the sea urchin Strongylocentrotus purpuratus. The Sp-tetraKCNG is a single polypeptide made of four KCNG domains similar to voltage-dependent Na(+) ..
  40. Vega Thurber R, Epel D. Apoptosis in early development of the sea urchin, Strongylocentrotus purpuratus. Dev Biol. 2007;303:336-46 pubmed
    ..cell death is infrequent and not obligatory during early embryogenesis of the purple sea urchin, Strongylocentrotus purpuratus. During the first 30 h of urchin development, fewer than 20% of embryos exhibit any cell death...
  41. Samanta M, Tongprasit W, Istrail S, Cameron R, Tu Q, Davidson E, et al. The transcriptome of the sea urchin embryo. Science. 2006;314:960-2 pubmed
    The sea urchin Strongylocentrotus purpuratus is a model organism for study of the genomic control circuitry underlying embryonic development. We examined the complete repertoire of genes expressed in the S...
  42. Terwilliger D, Buckley K, Brockton V, Ritter N, Smith L. Distinctive expression patterns of 185/333 genes in the purple sea urchin, Strongylocentrotus purpuratus: an unexpectedly diverse family of transcripts in response to LPS, beta-1,3-glucan, and dsRNA. BMC Mol Biol. 2007;8:16 pubmed
    ..Individual sea urchins were challenged with pathogen associated molecular patterns (PAMPs) (lipopolysaccharide, beta-1,3-glucan, or double stranded RNA), and changes in the 185/333 message repertoire were followed over time...
  43. Pearse J. Ecological role of purple sea urchins. Science. 2006;314:940-1 pubmed
    ..Their grazing limits algal biomass, and they are preyed upon by many predators. Purple sea urchins (Strongylocentrotus purpuratus) are among the best studied species...
  44. Garfield D, Haygood R, Nielsen W, Wray G. Population genetics of cis-regulatory sequences that operate during embryonic development in the sea urchin Strongylocentrotus purpuratus. Evol Dev. 2012;14:152-67 pubmed publisher
    ..FoxB, HE, SM30 a, and SM50) that function during the early development of the purple sea urchin, Strongylocentrotus purpuratus. Quantitative and qualitative measures of segregating variation are not conspicuously different ..
  45. Sutherby J, Giardini J, Nguyen J, Wessel G, Leguia M, Heyland A. Histamine is a modulator of metamorphic competence in Strongylocentrotus purpuratus (Echinodermata: Echinoidea). BMC Dev Biol. 2012;12:14 pubmed
    ..Here we test the premise that HA functions as a developmental modulator of metamorphic competence in the sea urchin Strongylocentrotus purpuratus.
  46. Agca C, Elhajj M, Klein W, Venuti J. Neurosensory and neuromuscular organization in tube feet of the sea urchin Strongylocentrotus purpuratus. J Comp Neurol. 2011;519:3566-79 pubmed publisher
    ..Recently, we showed that the Strongylocentrotus purpuratus genome contains orthologs of many mammalian retinal genes and that these genes are expressed in tube ..
  47. Matson P, Yu P, Sewell M, Hofmann G. Development under elevated pCO2 conditions does not affect lipid utilization and protein content in early life-history stages of the purple sea urchin, Strongylocentrotus purpuratus. Biol Bull. 2012;223:312-27 pubmed
    ..We examined the biochemical and morphological responses of Strongylocentrotus purpuratus during early development under ecologically relevant levels of pCO(2) (365, 1030, and 1450 ?atm) that ..
  48. Politi Y, Metzler R, Abrecht M, Gilbert B, Wilt F, Sagi I, et al. Transformation mechanism of amorphous calcium carbonate into calcite in the sea urchin larval spicule. Proc Natl Acad Sci U S A. 2008;105:17362-6 pubmed publisher
    ..We propose that the amorphous-crystal transformation propagates in a tortuous path through preexisting 40- to 100-nm amorphous units, via a secondary nucleation mechanism. ..
  49. Lun C, Bishop B, Smith L. Multitasking Immune Sp185/333 Protein, rSpTransformer-E1, and Its Recombinant Fragments Undergo Secondary Structural Transformation upon Binding Targets. J Immunol. 2017;198:2957-2966 pubmed publisher
    The purple sea urchin, Strongylocentrotus purpuratus, expresses a diverse immune response protein family called Sp185/333...
  50. Annunziata R, Arnone M. A dynamic regulatory network explains ParaHox gene control of gut patterning in the sea urchin. Development. 2014;141:2462-72 pubmed publisher
    ..Our findings offer a novel mechanistic explanation of how the control of transcription is linked to cell differentiation and morphogenesis for the development of a perfectly organized biological system such as the sea urchin larval gut. ..
  51. Killian C, Croker L, Wilt F. SpSM30 gene family expression patterns in embryonic and adult biomineralized tissues of the sea urchin, Strongylocentrotus purpuratus. Gene Expr Patterns. 2010;10:135-9 pubmed publisher
    The SpSM30 gene family of the sea urchin, Strongylocentrotus purpuratus, is comprised of six members, designated SpSM30A through SpSM30F (Livingston et al., 2006)...
  52. De Leon S, Davidson E. Information processing at the foxa node of the sea urchin endomesoderm specification network. Proc Natl Acad Sci U S A. 2010;107:10103-8 pubmed publisher
    ..This study shed light on the mesoderm-endoderm fate decision and provides a functional explanation, in terms of the genomic regulatory code, for the spatial and temporal expression of a key developmental control gene...
  53. Xu D, Sun L, Liu S, Zhang L, Yang H. Molecular cloning of hsf1 and hsbp1 cDNAs, and the expression of hsf1, hsbp1 and hsp70 under heat stress in the sea cucumber Apostichopus japonicus. Comp Biochem Physiol B Biochem Mol Biol. 2016;198:1-9 pubmed publisher
    ..hsbp1 in the sea cucumber Apostichopus japonicus, which are the second available for echinoderm (after Strongylocentrotus purpuratus), and the first available for holothurian...
  54. Robinson J. Proteolytic processing of a sea urchin, ECM-localized protein into lower mol mass species possessing collagen-cleavage activity. J Cell Biochem. 2006;99:816-23 pubmed
    ..This latter result defines the serine protease nature of the cleavage activities. Both the 40- and 38-kDa activities were found to comigrate with gelatin-cleaving activities present in the sea urchin embryo. ..
  55. Espinal Enríquez J, Priego Espinosa D, Darszon A, Beltrán C, Martínez Mekler G. Network model predicts that CatSper is the main Ca2+ channel in the regulation of sea urchin sperm motility. Sci Rep. 2017;7:4236 pubmed publisher
    ..Speract, such a peptide, after binding to its receptor in Strongylocentrotus purpuratus sperm flagella, triggers a signaling pathway that culminates with a train of intracellular calcium ..
  56. Cole A, Rizzo F, Martinez P, Fernandez Serra M, Arnone M. Two ParaHox genes, SpLox and SpCdx, interact to partition the posterior endoderm in the formation of a functional gut. Development. 2009;136:541-9 pubmed publisher
    We report the characterization of the ortholog of the Xenopus XlHbox8 ParaHox gene from the sea urchin Strongylocentrotus purpuratus, SpLox...
  57. Hayley M, Sun M, Merschrod E, Davis P, Robinson J. Biochemical analysis of the interaction of calcium with toposome: a major protein component of the sea urchin egg and embryo. J Cell Biochem. 2008;103:1464-71 pubmed
    ..Collectively, these results further enhance our understanding of the role of Ca(2+) in modulating the biological activity of toposome. ..
  58. Song J, Wessel G. Genes involved in the RNA interference pathway are differentially expressed during sea urchin development. Dev Dyn. 2007;236:3180-90 pubmed
    ..This study elucidated that genes involved in the RNAi silencing pathway have dynamic expression and, thus, may have regulatory roles during germ cell development and embryogenesis. ..
  59. Oulhen N, Swartz S, Laird J, Mascaro A, Wessel G. Transient translational quiescence in primordial germ cells. Development. 2017;144:1201-1210 pubmed publisher
    ..that the translational activity in the primordial germ cells (PGCs) of the sea urchin embryo (Strongylocentrotus purpuratus) is quiescent...
  60. Johnson G, Moore S. The carboxylesterase/cholinesterase gene family in invertebrate deuterostomes. Comp Biochem Physiol Part D Genomics Proteomics. 2012;7:83-93 pubmed publisher
    ..Here we have investigated the carboxylesterase/cholinesterase gene family in the sequenced genomes of Strongylocentrotus purpuratus (Echinodermata), Saccoglossus kowalevskii (Hemichordata), Ciona intestinalis (Urochordata) and ..
  61. Cameron R, Rowen L, Nesbitt R, Bloom S, Rast J, Berney K, et al. Unusual gene order and organization of the sea urchin hox cluster. J Exp Zool B Mol Dev Evol. 2006;306:45-58 pubmed
    ..The finished sequence from BAC clones from the genome of the sea urchin, Strongylocentrotus purpuratus, reveals a gene order wherein the anterior genes (Hox1, Hox2 and Hox3) lie nearest the posterior genes ..
  62. Cole A, Arnone M. Fluorescent in situ hybridization reveals multiple expression domains for SpBrn1/2/4 and identifies a unique ectodermal cell type that co-expresses the ParaHox gene SpLox. Gene Expr Patterns. 2009;9:324-8 pubmed publisher
    ..Double fluorescent in situ hybridization reveals that these cell pairs co-express both SpLox and SpBrn1/2/4, thus marking a novel cell type within the ciliary band of the sea urchin larvae...
  63. Oulhen N, Yoshida T, Yajima M, Song J, Sakuma T, Sakamoto N, et al. The 3'UTR of nanos2 directs enrichment in the germ cell lineage of the sea urchin. Dev Biol. 2013;377:275-83 pubmed publisher
    ..Three nanos homologs are present in the genome of the sea urchin Strongylocentrotus purpuratus (Sp), and each nanos mRNA accumulates specifically in the small micromere (sMic) lineage...
  64. Kiyama T, Klein W. SpGataE, a Strongylocentrotus purpuratus ortholog of mammalian Gata4/5/6: protein expression, interaction with putative target gene spec2a, and identification of friend of Gata factor SpFog1. Dev Genes Evol. 2007;217:651-63 pubmed
    ..In addition to providing new information on Gata and Fog proteins in sea urchins, the anti-SpGataE antibody developed here should be a useful reagent for future analysis of SpGataE function. ..
  65. Torreggiani A, Domènech J, Atrian S, Capdevila M, Tinti A. Raman study of in vivo synthesized Zn(II)-metallothionein complexes: structural insight into metal clusters and protein folding. Biopolymers. 2008;89:1114-24 pubmed publisher
  66. Pespeni M, Chan F, Menge B, Palumbi S. Signs of adaptation to local pH conditions across an environmental mosaic in the California Current Ecosystem. Integr Comp Biol. 2013;53:857-70 pubmed publisher
    ..Here we review what is known about genetic capacity for adaptation in the purple sea urchin, Strongylocentrotus purpuratus, a species that has evolved in the upwelling ecosystem of the Northeast Pacific Ocean...
  67. Wells T, Zhang G, Harley Z, Vaziri H. Genetic hypervariability in two distinct deuterostome telomerase reverse transcriptase genes and their early embryonic functions. Mol Biol Cell. 2009;20:464-80 pubmed publisher
    ..Surprisingly, we have identified two paralogous SpTERT-L and SpTERT-S genes with novel domains in Strongylocentrotus purpuratus (purple sea urchin)...
  68. Yamakawa N, Sato C, Miyata S, Maehashi E, Toriyama M, Sato N, et al. Development of sensitive chemical and immunochemical methods for detecting sulfated sialic acids and their application to glycoconjugates from sea urchin sperm and eggs. Biochimie. 2007;89:1396-408 pubmed
    ..Thus, 8-O-sulfation is dependent on the species, gametic cell-type, site-localization of the eggs, and glycoconjugates...
  69. Arenas Mena C, Cameron R, Davidson E. Hindgut specification and cell-adhesion functions of Sphox11/13b in the endoderm of the sea urchin embryo. Dev Growth Differ. 2006;48:463-72 pubmed
    Sphox11/13b is one of the two hox genes of Strongylocentrotus purpuratus expressed in the embryo...
  70. Braun T, Woollard A. RUNX factors in development: lessons from invertebrate model systems. Blood Cells Mol Dis. 2009;43:43-8 pubmed publisher
    ..of these studies in three invertebrate systems, the fruit fly Drosophila melanogaster, the sea urchin Strongylocentrotus purpuratus and the nematode Caenorhabditis elegans...