penaeidae

Summary

Summary: A family of CRUSTACEA, order DECAPODA, comprising the penaeid shrimp. Species of the genus Penaeus are the most important commercial shrimp throughout the world.

Top Publications

  1. del Carmen Flores Miranda M, Luna González A, Córdova A, Fierro Coronado J, Partida Arangure B, Pintado J, et al. Isolation and characterization of infectious Vibrio sinaloensis strains from the Pacific shrimp Litopenaeus vannamei (Decapoda: Penaeidae). Rev Biol Trop. 2012;60:567-76 pubmed
    ..vannamei. The LD50 value was 1.178x10(5)CFU/g body weight. V sinaloensis may act as opportunistic pathogens for cultured L. vannamei...
  2. Wang P, Gu Z, Wan D, Zhu W, Qiu W, Weng S, et al. Litopenaeus vannamei sterile-alpha and armadillo motif containing protein (LvSARM) is involved in regulation of Penaeidins and antilipopolysaccharide factors. PLoS ONE. 2013;8:e52088 pubmed publisher
    ..alginolyticus infection. Taken together, our results reveal that LvSARM may be a novel component of the shrimp Toll pathway that negatively regulates shrimp AMPs, particularly Penaeidins and antilipopolysaccharide factors...
  3. Chansela P, Goto Inoue N, Zaima N, Hayasaka T, Sroyraya M, Kornthong N, et al. Composition and localization of lipids in Penaeus merguiensis ovaries during the ovarian maturation cycle as revealed by imaging mass spectrometry. PLoS ONE. 2012;7:e33154 pubmed publisher
    ..Knowledge of lipid compositions and localization could be helpful for formulating the diet for female broodstocks to promote fecundity and larval production...
  4. Li C, Chen Y, Zhang S, Lu L, Chen Y, Chai J, et al. Identification, characterization, and function analysis of the Cactus gene from Litopenaeus vannamei. PLoS ONE. 2012;7:e49711 pubmed publisher
    ..Differently, the LvCactus expression levels obviously decreased during white spot syndrome virus (WSSV) infection, indicating the feedback regulatory pathway of LvCactus/LvDorsal could be modified by WSSV...
  5. Chen Y, Zhao L, Pang L, Li X, Weng S, He J. Identification and characterization of Inositol-requiring enzyme-1 and X-box binding protein 1, two proteins involved in the unfolded protein response of Litopenaeus vannamei. Dev Comp Immunol. 2012;38:66-77 pubmed publisher
    ..Taken together, these results confirm that the IRE1-XBP1 pathway is important for L. vannamei environmental stress resistance, suggest that L. vannamei IRE1-XBP1 may activated by WSSV and be annexed to serve the virus...
  6. Li S, Zhang X, Sun Z, Li F, Xiang J. Transcriptome analysis on Chinese shrimp Fenneropenaeus chinensis during WSSV acute infection. PLoS ONE. 2013;8:e58627 pubmed publisher
    ..In addition, the transcriptome data provides detail information for identifying novel genes in absence of the genome database of shrimp...
  7. Wang P, Gu Z, Wan D, Zhu W, Qiu W, Chen Y, et al. Litopenaeus vannamei Toll-interacting protein (LvTollip) is a potential negative regulator of the shrimp Toll pathway involved in the regulation of the shrimp antimicrobial peptide gene penaeidin-4 (PEN4). Dev Comp Immunol. 2013;40:266-77 pubmed publisher
    ..Our results suggested that LvTollip might be involved in the negative regulation of PEN4 and that LvTollip expression was responsive to microbial infections...
  8. Goncalves P, Vernal J, Rosa R, Yepiz Plascencia G, de Souza C, Barracco M, et al. Evidence for a novel biological role for the multifunctional ?-1,3-glucan binding protein in shrimp. Mol Immunol. 2012;51:363-7 pubmed publisher
    ..Herein, we have improved our knowledge about the ?GBP family by the characterization of a novel biological role for this multifunctional protein in shrimp...
  9. Zhang S, Li C, Yan H, Qiu W, Chen Y, Wang P, et al. Identification and function of myeloid differentiation factor 88 (MyD88) in Litopenaeus vannamei. PLoS ONE. 2012;7:e47038 pubmed publisher
    ..These results suggested that LvMyD88 may play a role in antibacterial and antiviral response in L. vannamei. To our knowledge, this is the first report on MyD88 in shrimp and a variant of MyD88 gene in invertebrates...

More Information

Publications62

  1. Leu J, Chen Y, Chen L, Chen K, Huang H, Ho J, et al. Litopenaeus vannamei inhibitor of apoptosis protein 1 (LvIAP1) is essential for shrimp survival. Dev Comp Immunol. 2012;38:78-87 pubmed publisher
    ..In LvIAP1-silenced shrimp, the number of circulating haemocytes decreased dramatically because of extensive apoptosis. This suggested that LvIAP1 is central to the regulation of shrimp haemocyte apoptosis...
  2. Chaikeeratisak V, Somboonwiwat K, Wang H, Lo C, Tassanakajon A. Proteomic analysis of differentially expressed proteins in the lymphoid organ of Vibrio harveyi-infected Penaeus monodon. Mol Biol Rep. 2012;39:6367-77 pubmed publisher
    ..3%) and a dramatic reduction of the total hemocyte numbers in the survival shrimps. These altered proteins are likely to play essential roles in shrimp defense against the pathogenic bacterium V. harveyi...
  3. Soto Rodriguez S, Gomez Gil B, Lozano R, del Rio Rodríguez R, Diéguez A, Romalde J. Virulence of Vibrio harveyi responsible for the "Bright-red" Syndrome in the Pacific white shrimp Litopenaeus vannamei. J Invertebr Pathol. 2012;109:307-17 pubmed publisher
    ..i. LO was the target organ of BRS. Necrosis of the MU at the injection site was the main difference in comparison to other shrimp vibriosis...
  4. Tsai Y, Lin Y, Chou P, Teng P, Lee P. Detection of white spot syndrome virus by polymerase chain reaction performed under insulated isothermal conditions. J Virol Methods. 2012;181:134-7 pubmed publisher
    ..iiPCR has a potential as a low-cost method for sensitive, specific and rapid detection of pathogens...
  5. Leu J, Lin S, Huang J, Chen T, Lo C. A model for apoptotic interaction between white spot syndrome virus and shrimp. Fish Shellfish Immunol. 2013;34:1011-7 pubmed publisher
    ..This is a life and death struggle because the virus needs to prevent apoptosis in order to replicate. If WSSV succeeds in replicating in sufficient numbers, this will result in the death of the infected penaeid shrimp host...
  6. Li C, Weng S, Chen Y, Yu X, Lu L, Zhang H, et al. Analysis of Litopenaeus vannamei transcriptome using the next-generation DNA sequencing technique. PLoS ONE. 2012;7:e47442 pubmed publisher
    ..The now available transcriptome data of L. vannamei are insufficient for research requirements, and have not been adequately assembled and annotated...
  7. Huang T, Zhang X. Contribution of the argonaute-1 isoforms to invertebrate antiviral defense. PLoS ONE. 2012;7:e50581 pubmed publisher
    ..It was revealed that Ago1C had no effect on virus infection. Therefore, the current study presented the first report on the contribution of Ago isoforms in the invertebrate defense against virus infection...
  8. Wang D, Li F, Li S, Chi Y, Wen R, Feng N, et al. An I?B homologue (FcCactus) in Chinese shrimp Fenneropenaeus chinensis. Dev Comp Immunol. 2013;39:352-62 pubmed publisher
    ..The present data showed that FcCactus might play important roles in regulating the immune response of shrimp...
  9. Andriantahina F, Liu X, Feng T, Xiang J. Current status of genetics and genomics of reared penaeid shrimp: information relevant to access and benefit sharing. Mar Biotechnol (NY). 2013;15:399-412 pubmed publisher
  10. Zhang X, Zhang Y, Scheuring C, Zhang H, Huan P, Wang B, et al. Construction and characterization of a bacterial artificial chromosome (BAC) library of Pacific white shrimp, Litopenaeus vannamei. Mar Biotechnol (NY). 2010;12:141-9 pubmed publisher
  11. Wang P, Wan D, Gu Z, Deng X, Weng S, Yu X, et al. Litopenaeus vannamei tumor necrosis factor receptor-associated factor 6 (TRAF6) responds to Vibrio alginolyticus and white spot syndrome virus (WSSV) infection and activates antimicrobial peptide genes. Dev Comp Immunol. 2011;35:105-14 pubmed publisher
    ..7- and 2.3-fold over the control at 3h in gills and hepatopancreas, respectively. These results indicated that LvTRAF6 may play a crucial role in antibacterial and antiviral responses via regulation of AMP gene expression...
  12. Sirirustananun N, Chen J, Lin Y, Yeh S, Liou C, Chen L, et al. Dietary administration of a Gracilaria tenuistipitata extract enhances the immune response and resistance against Vibrio alginolyticus and white spot syndrome virus in the white shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2011;31:848-55 pubmed publisher
    ..alginolyticus and WSSV infections. Shrimp fed the extract-containing diets showed a higher and continuous increase in the humoral response indicating its persistent role in innate immunity...
  13. Rattanama P, Srinitiwarawong K, Thompson J, Pomwised R, Supamattaya K, Vuddhakul V. Shrimp pathogenicity, hemolysis, and the presence of hemolysin and TTSS genes in Vibrio harveyi isolated from Thailand. Dis Aquat Organ. 2009;86:113-22 pubmed publisher
    ..Random amplified polymorphic DNA (RAPD) analysis revealed a high degree of genetic diversity in all V harveyi isolates, and there were no correlations among the hhl-positive isolates or the pathogenic strains...
  14. Chuang K, Ho S, Song Y. Cloning and expression analysis of heat shock cognate 70 gene promoter in tiger shrimp (Penaeus monodon). Gene. 2007;405:10-8 pubmed
    ..1) on Sf21 cells significantly increased the hsc70 promoter activity. In addition, the effects of amino acid analogs and arsenic acid incubation with the cells on the hsc70 promoter activity were examined...
  15. Liu C, Chiu C, Ho P, Wang S. Improvement in the growth performance of white shrimp, Litopenaeus vannamei, by a protease-producing probiotic, Bacillus subtilis E20, from natto. J Appl Microbiol. 2009;107:1031-41 pubmed publisher
    ..To isolate and identify a benefic bacterium, Bacillus subtilis E20, from natto (fermented soybeans), and incorporate it into shrimp feed to promote shrimp growth performance...
  16. Labreuche Y, O Leary N, de la Vega E, Veloso A, Gross P, Chapman R, et al. Lack of evidence for Litopenaeus vannamei Toll receptor (lToll) involvement in activation of sequence-independent antiviral immunity in shrimp. Dev Comp Immunol. 2009;33:806-10 pubmed publisher
    ..In contrast, gene-specific dsRNA injected to specifically silence lToll expression activated an antiviral response. These data strongly suggest that shrimp lToll plays no role in dsRNA-induced antiviral immunity...
  17. Leelatanawit R, Uawisetwathana U, Klinbunga S, Karoonuthaisiri N. A cDNA microarray, UniShrimpChip, for identification of genes relevant to testicular development in the black tiger shrimp (Penaeus monodon). BMC Mol Biol. 2011;12:15 pubmed publisher
    ..UniShrimpChip was used to study testicular development by comparing gene expression levels of wild brooders from the West and East coasts of Thailand and domesticated brooders with different ages (10-, 14-, 18-month-old)...
  18. Sittidilokratna N, Chotwiwatthanakun C, Wijegoonawardane P, Unajak S, Boonnad A, Wangnai W, et al. A virulent isolate of yellow head nidovirus contains a deformed envelope glycoprotein gp116. Virology. 2009;384:192-200 pubmed publisher
  19. Tonganunt M, Nupan B, Saengsakda M, Suklour S, Wanna W, Senapin S, et al. The role of Pm-fortilin in protecting shrimp from white spot syndrome virus (WSSV) infection. Fish Shellfish Immunol. 2008;25:633-7 pubmed publisher
    ..This is a novel polypeptide of 93 amino acids with a number of XPPX signature sequences that are often reported to have a function in antiviral peptides...
  20. Huang X, Zhao L, Zhang H, Xu X, Jia X, Chen Y, et al. Shrimp NF-?B binds to the immediate-early gene ie1 promoter of white spot syndrome virus and upregulates its activity. Virology. 2010;406:176-80 pubmed publisher
    ..We suggested that WSSV may annex the shrimp NF-?B system, which it uses to enhance the expression of viral immediate-early genes...
  21. Wang Y, Chang P, Chen H. Tissue expressions of nine genes important to immune defence of the Pacific white shrimp Litopenaeus vannamei. Fish Shellfish Immunol. 2007;23:1161-77 pubmed
  22. Sittidilokratna N, Dangtip S, Cowley J, Walker P. RNA transcription analysis and completion of the genome sequence of yellow head nidovirus. Virus Res. 2008;136:157-65 pubmed publisher
    ..Intergenic sequences upstream of ORF2 and ORF3 share high identity with GAV, particularly in the conserved domains predicted to mediate sgmRNA transcription...
  23. Gao H, Li F, Dong B, Zhang Q, Xiang J. Molecular cloning and characterisation of prophenoloxidase (ProPO) cDNA from Fenneropenaeus chinensis and its transcription injected by Vibrio anguillarum. Mol Biol Rep. 2009;36:1159-66 pubmed publisher
    ..The time-course change of ProPO mRNA levels in challenge experiment showed that ProPO mRNA transcripts had the biggest change extent in lymphoid organ...
  24. Xu J, Wu S, Zhang X. Novel function of QM protein of shrimp (Penaeus japonicus) in regulation of phenol oxidase activity by interaction with hemocyanin. Cell Physiol Biochem. 2008;21:473-80 pubmed publisher
    ..This discovery showed a novel aspect of QM protein in arthropod immune response, which contributed a better understanding to the still poorly understood molecular events involved in innate immunity of arthropods...
  25. Sánchez Paz A. White spot syndrome virus: an overview on an emergent concern. Vet Res. 2010;41:43 pubmed publisher
    ..This review provides a state-of-the-art overview of the topic, and emphasizes the current progress and future direction for the development of WSSV control strategies...
  26. Treerattrakool S, Panyim S, Chan S, Withyachumnarnkul B, Udomkit A. Molecular characterization of gonad-inhibiting hormone of Penaeus monodon and elucidation of its inhibitory role in vitellogenin expression by RNA interference. FEBS J. 2008;275:970-80 pubmed publisher
    ..This is the first report to demonstrate the use of double-stranded RNA to elucidate the function of GIH in P. monodon...
  27. Karoonuthaisiri N, Sittikankeaw K, Preechaphol R, Kalachikov S, Wongsurawat T, Uawisetwathana U, et al. ReproArray(GTS): a cDNA microarray for identification of reproduction-related genes in the giant tiger shrimp Penaeus monodon and characterization of a novel nuclear autoantigenic sperm protein (NASP) gene. Comp Biochem Physiol Part D Genomics Proteomics. 2009;4:90-9 pubmed publisher
    ..This study indicated that ReproArray(GTS) is effective for high-throughput screening of genes that play important roles in ovarian development of P. monodon...
  28. Li C, Yan H, Song Y. Tiger shrimp (Penaeus monodon) penaeidin possesses cytokine features to promote integrin-mediated granulocyte and semi-granulocyte adhesion. Fish Shellfish Immunol. 2010;28:1-9 pubmed publisher
    ..In conclusion, penaeidin possesses an integrin-beta-mediated cytokine feature that promotes shrimp granulocyte and semi-granulocyte adhesion. This is the first report about functional shrimp cytokine...
  29. Pongsomboon S, Tang S, Boonda S, Aoki T, Hirono I, Tassanakajon A. A cDNA microarray approach for analyzing transcriptional changes in Penaeus monodon after infection by pathogens. Fish Shellfish Immunol. 2011;30:439-46 pubmed publisher
    ..Shrimp genes specifically upregulated by each particular pathogen are identified and are summarized...
  30. Pradeep B, Shekar M, Karunasagar I, Karunasagar I. Characterization of variable genomic regions of Indian white spot syndrome virus. Virology. 2008;376:24-30 pubmed publisher
    ..The Indian strains were closely related to Thailand strains suggesting movement of a putative ancestor from Thailand to other parts of the world including India...
  31. Uawisetwathana U, Leelatanawit R, Klanchui A, Prommoon J, Klinbunga S, Karoonuthaisiri N. Insights into eyestalk ablation mechanism to induce ovarian maturation in the black tiger shrimp. PLoS ONE. 2011;6:e24427 pubmed publisher
  32. Gorbach D, Hu Z, Du Z, Rothschild M. Mining ESTs to determine the usefulness of SNPs across shrimp species. Anim Biotechnol. 2010;21:100-3 pubmed publisher
    Expressed sequence tag (EST) libraries from members of the Penaeidae family and brine shrimp (Artemia franciscana) are currently the primary source of sequence data for shrimp species...
  33. Rendón Rodríguez S, Macías Regalado E, Calderón Pérez J, Núñez Pastén A, Solís Ibarra R. Comparison of some reproductive characteristics of farmed and wild white shrimp males Litopenaeus vannamei (Decapoda: Penaeidae). Rev Biol Trop. 2007;55:199-206 pubmed
    ..3% and 76.6%, respectively) and irregular shape (35.8 % and 17.7 %). The less frequent occurrences were those of bent (10.2 % and 4.29%) and double spike (4.7% and 1.41%)...
  34. Wang W, Zhang X. Comparison of antiviral efficiency of immune responses in shrimp. Fish Shellfish Immunol. 2008;25:522-7 pubmed publisher
  35. Gangnonngiw W, Anantasomboon G, Sang oum W, Sriurairatana S, Sritunyalucksana K, Flegel T. Non-virulence of a recombinant shrimp nidovirus is associated with its non structural gene sequence and not a large structural gene deletion. Virology. 2009;385:161-8 pubmed publisher
    ..Overall, the information suggested that lack of A-YHV virulence was associated with the NS gene sequence linked to ORF1b rather than the deletion in ORF3...
  36. Rajeshkumar S, Venkatesan C, Sarathi M, Sarathbabu V, Thomas J, Anver Basha K, et al. Oral delivery of DNA construct using chitosan nanoparticles to protect the shrimp from white spot syndrome virus (WSSV). Fish Shellfish Immunol. 2009;26:429-37 pubmed publisher
    ..The study also correlated the changes in the level of immunological parameters with the survival percentage and protective efficacy of oral route of DNA construct against WSSV in shrimp...
  37. Wang S, Liu N, Chen A, Zhao X, Wang J. TRBP homolog interacts with eukaryotic initiation factor 6 (eIF6) in Fenneropenaeus chinensis. J Immunol. 2009;182:5250-8 pubmed publisher
    ..These results indicate that Fc-TRBP and Fc-eIF6 may be components of the RNA-induced silencing complex (RISC), and thereby play a crucial role in the antiviral defense response of shrimp...
  38. Tourtip S, Wongtripop S, Stentiford G, Bateman K, Sriurairatana S, Chavadej J, et al. Enterocytozoon hepatopenaei sp. nov. (Microsporida: Enterocytozoonidae), a parasite of the black tiger shrimp Penaeus monodon (Decapoda: Penaeidae): Fine structure and phylogenetic relationships. J Invertebr Pathol. 2009;102:21-9 pubmed publisher
    ..bieneusi, the parasite was considered to be a new species, E. hepatopenaei, within the genus Enterocytozoon...
  39. Ninawe A, Selvin J. Probiotics in shrimp aquaculture: avenues and challenges. Crit Rev Microbiol. 2009;35:43-66 pubmed publisher
    ..The present review highlights the potential sources of probiotics, mechanism of action, diversity of probiotic microbes and challenges of probiotic usage in shrimp aquaculture...
  40. Li F, Yan H, Wang D, Priya T, Li S, Wang B, et al. Identification of a novel relish homolog in Chinese shrimp Fenneropenaeus chinensis and its function in regulating the transcription of antimicrobial peptides. Dev Comp Immunol. 2009;33:1093-101 pubmed publisher
    ..Therefore, we suggest that FcRelish identified in the present study is closely related to the transcription of AMP, and then we inferred that Imd pathway might exist in shrimp...
  41. Nupan B, Phongdara A, Saengsakda M, Leu J, Lo C. Shrimp Pm-fortilin inhibits the expression of early and late genes of white spot syndrome virus (WSSV) in an insect cell model. Dev Comp Immunol. 2011;35:469-75 pubmed publisher
    ..This is the first time that an insect cell line has been used to demonstrate interaction between a shrimp gene and genes of a shrimp virus...
  42. Veloso A, Warr G, Browdy C, Chapman R. The transcriptomic response to viral infection of two strains of shrimp (Litopenaeus vannamei). Dev Comp Immunol. 2011;35:241-6 pubmed publisher
    ..In contrast to TSV challenge, YSV either failed to perturb the host transcriptome or created a "confused" response that was difficult to interpret...
  43. Wongsurawat T, Leelatanawit R, Thamniemdee N, Uawisetwathana U, Karoonuthaisiri N, Menasveta P, et al. Identification of testis-relevant genes using in silico analysis from testis ESTs and cDNA microarray in the black tiger shrimp (Penaeus monodon). BMC Mol Biol. 2010;11:55 pubmed publisher
  44. Preechaphol R, Klinbunga S, Yamano K, Menasveta P. Molecular cloning and expression of progestin membrane receptor component 1 (Pgmrc1) of the giant tiger shrimp Penaeus monodon. Gen Comp Endocrinol. 2010;168:440-9 pubmed publisher
    ..Taken the information together, Pgmrc1 gene products seem to play the important role on ovarian development and may be used as the bioindicator for monitoring progression of oocyte maturation of P. monodon...
  45. Ai H, Huang Y, Li S, Weng S, Yu X, He J. Characterization of a prophenoloxidase from hemocytes of the shrimp Litopenaeus vannamei that is down-regulated by white spot syndrome virus. Fish Shellfish Immunol. 2008;25:28-39 pubmed publisher
    ..Our results suggest that proPO-b is a main transcript form of proPO gene in L. vannamei, and it may play a role in defence against WSSV virus...
  46. Lightner D, Redman R. Opportunities for training in shrimp diseases. Dev Biol (Basel). 2007;129:137-46 pubmed
    ..The trend towards more formal training programs in shrimp diseases and disease management is likely to continue as the industry continues to mature and become increasingly sustainable...
  47. Escobedo Bonilla C, Alday Sanz V, Wille M, Sorgeloos P, Pensaert M, Nauwynck H. A review on the morphology, molecular characterization, morphogenesis and pathogenesis of white spot syndrome virus. J Fish Dis. 2008;31:1-18 pubmed
    ..The aim of this review is to present an update of the knowledge generated so far on different aspects of WSSV organization, morphogenesis, pathology and pathogenesis...
  48. Amparyup P, Donpudsa S, Tassanakajon A. Shrimp single WAP domain (SWD)-containing protein exhibits proteinase inhibitory and antimicrobial activities. Dev Comp Immunol. 2008;32:1497-509 pubmed publisher
    ..98nM. Thus, rSWDPm2 may contribute to the inhibitory regulation of subtilisin A from bacterial infection and P. monodon SWD protein likely function as immune effectors in defense against invasion of shrimp pathogens...
  49. Ayuso R, Grishina G, Bardina L, Carrillo T, Blanco C, Ibañez M, et al. Myosin light chain is a novel shrimp allergen, Lit v 3. J Allergy Clin Immunol. 2008;122:795-802 pubmed publisher
    ..Shellfish allergy is a prevalent, long-lasting disorder usually persisting throughout life. Few options are available for treatment, and avoidance is the only therapy recommended...
  50. Dhar A, Bowers R, Licon K, Veazey G, Read B. Validation of reference genes for quantitative measurement of immune gene expression in shrimp. Mol Immunol. 2009;46:1688-95 pubmed publisher
    ..The ability to compare the healthy and WSSV infected samples in parallel by the regression analysis makes this method a very useful approach while identifying the optimal reference gene for gene expression analysis...
  51. Charoensapsri W, Amparyup P, Hirono I, Aoki T, Tassanakajon A. Gene silencing of a prophenoloxidase activating enzyme in the shrimp, Penaeus monodon, increases susceptibility to Vibrio harveyi infection. Dev Comp Immunol. 2009;33:811-20 pubmed publisher
    ..These results indicate that PmPPAE1 functions in the proPO system and is an important component in the shrimp immune system...
  52. Wang P, Gu Z, Huang X, Liu B, Deng X, Ai H, et al. An immune deficiency homolog from the white shrimp, Litopenaeus vannamei, activates antimicrobial peptide genes. Mol Immunol. 2009;46:1897-904 pubmed publisher
    ..To our knowledge, this is the first report that LvIMD participates in innate signaling to activate the expression of AMP genes in shrimp...
  53. Chen Y, Jia X, Zhao L, Li C, Zhang S, Chen Y, et al. Identification and functional characterization of Dicer2 and five single VWC domain proteins of Litopenaeus vannamei. Dev Comp Immunol. 2011;35:661-71 pubmed publisher
    ..Furthermore, these results also suggested that LvDcr2 may engage in non-specific activation of anti-viral immunity...