ticks

Summary

Summary: Blood-sucking acarid parasites of the order Ixodida comprising two families: the softbacked ticks (ARGASIDAE) and hardbacked ticks (IXODIDAE). Ticks are larger than their relatives, the MITES. They penetrate the skin of their host by means of highly specialized, hooked mouth parts and feed on its blood. Ticks attack all groups of terrestrial vertebrates. In humans they are responsible for many TICK-BORNE DISEASES, including the transmission of ROCKY MOUNTAIN SPOTTED FEVER; TULAREMIA; BABESIOSIS; AFRICAN SWINE FEVER; and RELAPSING FEVER. (From Barnes, Invertebrate Zoology, 5th ed, pp543-44)

Top Publications

  1. Dantas Torres F, Chomel B, Otranto D. Ticks and tick-borne diseases: a One Health perspective. Trends Parasitol. 2012;28:437-46 pubmed publisher
    ..difficult, because it requires the disruption of a complex transmission chain, involving vertebrate hosts and ticks, which interact in a constantly changing environment...
  2. Ojogun N, Kahlon A, Ragland S, Troese M, Mastronunzio J, Walker N, et al. Anaplasma phagocytophilum outer membrane protein A interacts with sialylated glycoproteins to promote infection of mammalian host cells. Infect Immun. 2012;80:3748-60 pubmed publisher
    ..OmpA is transcriptionally induced during transmission feeding of A. phagocytophilum-infected ticks on mice and is upregulated during invasion of HL-60 cells. OmpA is presented on the pathogen's surface...
  3. McCoy K, Léger E, Dietrich M. Host specialization in ticks and transmission of tick-borne diseases: a review. Front Cell Infect Microbiol. 2013;3:57 pubmed publisher
    ..The question of whether ticks are typically host specialists or host generalists has been subject to much debate over the last half-century...
  4. Xiong H, Barker S, Burger T, Raoult D, Shao R. Heteroplasmy in the mitochondrial genomes of human lice and ticks revealed by high throughput sequencing. PLoS ONE. 2013;8:e73329 pubmed publisher
    ..For comparison, we also sequenced the entire coding regions of the mt genomes of seven species of ticks, which have the typical mitochondrial genome organization of bilateral animals...
  5. Hajdusek O, Sima R, Ayllón N, Jalovecká M, Perner J, De La Fuente J, et al. Interaction of the tick immune system with transmitted pathogens. Front Cell Infect Microbiol. 2013;3:26 pubmed publisher
    b>Ticks are hematophagous arachnids transmitting a wide variety of pathogens including viruses, bacteria, and protozoans to their vertebrate hosts...
  6. Karim S, Singh P, Ribeiro J. A deep insight into the sialotranscriptome of the gulf coast tick, Amblyomma maculatum. PLoS ONE. 2011;6:e28525 pubmed publisher
    ..Because of these properties, saliva helps blood feeding as well as help the establishment of pathogens that can be transmitted during blood feeding...
  7. Guedes E, Leite R, Pacheco R, Silveira I, Labruna M. Rickettsia species infecting Amblyomma ticks from an area endemic for Brazilian spotted fever in Brazil. Rev Bras Parasitol Vet. 2011;20:308-11 pubmed
    This study reports rickettsial infection in Amblyomma cajennense and Amblyomma dubitatum ticks collected in an area of the state of Minas Gerais, Brazil, where Brazilian spotted fever is considered endemic...
  8. Aung K, Boldbaatar D, Umemiya Shirafuji R, Liao M, Xuenan X, Suzuki H, et al. Scavenger receptor mediates systemic RNA interference in ticks. PLoS ONE. 2011;6:e28407 pubmed publisher
    ..B scavenger receptor CD36 (SRB) mediated the uptake of exogenous dsRNAs in the induction of the RNAi responses in ticks. Unfed female Haemaphysalis longicornis ticks were injected with a single or a combination of H...
  9. Dodd K, Bird B, Khristova M, Albarino C, Carroll S, Comer J, et al. Ancient ancestry of KFDV and AHFV revealed by complete genome analyses of viruses isolated from ticks and mammalian hosts. PLoS Negl Trop Dis. 2011;5:e1352 pubmed publisher
    ..To gain a better understanding of the evolutionary history of AHFV and KFDV, we analyzed the full length genomes of 16 AHFV and 3 KFDV isolates...

More Information

Publications62

  1. Lempereur L, Lebrun M, Cuvelier P, Sépult G, Caron Y, Saegerman C, et al. Longitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium. Parasitol Res. 2012;110:1525-30 pubmed publisher
    ..8%, 77%, and 56.9%, respectively. A total of 805 Ixodes ricinus ticks were collected at the same time from both cattle (feeding ticks) and grazed pastures (questing ticks)...
  2. Nogueira S, Smith A, Qin J, Pal U. A surface enolase participates in Borrelia burgdorferi-plasminogen interaction and contributes to pathogen survival within feeding ticks. Infect Immun. 2012;80:82-90 pubmed publisher
    ..in vivo, however, with a variable temporal and spatial expression during spirochete infection in mice and ticks. Despite an extracellular exposure of the antigen and a potential role in host-pathogen interaction, active ..
  3. Nakao R, Abe T, Nijhof A, Yamamoto S, Jongejan F, Ikemura T, et al. A novel approach, based on BLSOMs (Batch Learning Self-Organizing Maps), to the microbiome analysis of ticks. ISME J. 2013;7:1003-15 pubmed publisher
    b>Ticks transmit a variety of viral, bacterial and protozoal pathogens, which are often zoonotic. The aim of this study was to identify diverse tick microbiomes, which may contain as-yet unidentified pathogens, using a metagenomic approach...
  4. Policastro P, Raffel S, Schwan T. Borrelia hermsii acquisition order in superinfected ticks determines transmission efficiency. Infect Immun. 2013;81:2899-908 pubmed publisher
    ..We infected mice with isolates from each group and fed ticks sequentially on these mice...
  5. Margos G, Wilske B, Sing A, Hizo Teufel C, Cao W, Chu C, et al. Borrelia bavariensis sp. nov. is widely distributed in Europe and Asia. Int J Syst Evol Microbiol. 2013;63:4284-8 pubmed publisher
    ..nov. in 2009, additional samples available from humans and ticks from Europe and Mongolia, respectively, have been used to further characterize Borrelia strains belonging to this ..
  6. M ghirbi Y, Yaïch H, Ghorbel A, Bouattour A. Anaplasma phagocytophilum in horses and ticks in Tunisia. Parasit Vectors. 2012;5:180 pubmed
    ..We used direct and indirect methods to compare and evaluate exposure to A. phagocytophilum in horses in northern Tunisia...
  7. Toledo R, Tamekuni K, Filho M, Haydu V, Barbieri A, Hiltel A, et al. Infection by spotted fever rickettsiae in people, dogs, horses and ticks in Londrina, Parana State, Brazil. Zoonoses Public Health. 2011;58:416-23 pubmed publisher
    ..With the objective of gathering information on the circulation of SFG rickettsiae in Londrina, Parana state, ticks from dogs and horses and also blood from dogs, horses and humans were collected in a neighbourhood of the city ..
  8. Reye A, Arinola O, Hübschen J, Muller C. Pathogen prevalence in ticks collected from the vegetation and livestock in Nigeria. Appl Environ Microbiol. 2012;78:2562-8 pubmed publisher
    b>Ticks are important disease vectors that can cause considerable economic losses by affecting animal health and productivity, especially in tropical and subtropical regions...
  9. Cicuttin G, Nava S. Molecular identification of Rickettsia parkeri infecting Amblyomma triste ticks in an area of Argentina where cases of rickettsiosis were diagnosed. Mem Inst Oswaldo Cruz. 2013;108:123-5 pubmed
    ..500-bp fragment of the gene encoding a 190-kDa outer membrane protein. Three (6.97%) of 43 A. triste ticks were determined to be positive for R. parkeri. These results provide strong evidence that A...
  10. Scott M, Harmon J, Tsao J, Jones C, Hickling G. Reverse line blot probe design and polymerase chain reaction optimization for bloodmeal analysis of ticks from the eastern United States. J Med Entomol. 2012;49:697-709 pubmed
    Determining the host preference of vector ticks is vital to elucidating the eco-epidemiology of the diseases they spread...
  11. Ristow L, Miller H, Padmore L, Chettri R, Salzman N, Caimano M, et al. The ??-integrin ligand of Borrelia burgdorferi is critical for infection of mice but not ticks. Mol Microbiol. 2012;85:1105-18 pubmed publisher
    ..p66 bacteria were able to survive in ticks through the larva to nymph moult, but were non-infectious in mice when delivered by tick bite...
  12. Billeter S, Caceres A, Gonzales Hidalgo J, Luna Caypo D, Kosoy M. Molecular detection of Bartonella species in ticks from Peru. J Med Entomol. 2011;48:1257-60 pubmed
    A total of 103 ticks, collected from canines, horses, donkeys, and snakes from Peru, were screened for the presence of Bartonella DNA by polymerase chain reaction analysis...
  13. Latif A, Putterill J, de Klerk D, Pienaar R, Mans B. Nuttalliella namaqua (Ixodoidea: Nuttalliellidae): first description of the male, immature stages and re-description of the female. PLoS ONE. 2012;7:e41651 pubmed publisher
    ..Females possess features of hard and soft ticks and have been designated as the "missing link" between the main tick families...
  14. Franke J, Hildebrandt A, Dorn W. Exploring gaps in our knowledge on Lyme borreliosis spirochaetes--updates on complex heterogeneity, ecology, and pathogenicity. Ticks Tick Borne Dis. 2013;4:11-25 pubmed publisher
    ..Furthermore, there is evidence that ticks, reservoir hosts, and patients can be coinfected with multiple Borrelia spp...
  15. Knap N, Korva M, Dolinšek V, Sekirnik M, Trilar T, Avsic Zupanc T. Patterns of tick-borne encephalitis virus infection in rodents in Slovenia. Vector Borne Zoonotic Dis. 2012;12:236-42 pubmed publisher
    ..Rodents can therefore be used as a useful indicator of the circulation of TBEV in an area...
  16. Norte A, de Carvalho I, Ramos J, Goncalves M, Gern L, Nuncio M. Diversity and seasonal patterns of ticks parasitizing wild birds in western Portugal. Exp Appl Acarol. 2012;58:327-39 pubmed publisher
    The diversity and abundance of questing ticks and ticks parasitizing birds was assessed during 1 year in two recreational forests in western Portugal, a suburban forest and an enclosed game area...
  17. Richards A. Worldwide detection and identification of new and old rickettsiae and rickettsial diseases. FEMS Immunol Med Microbiol. 2012;64:107-10 pubmed publisher
    ..such as serum, blood, and tissue biopsies and with environmental samples such as arthropod vectors including ticks, fleas, lice, and mites, and blood and tissue specimens from small mammal collections and from wild and domestic ..
  18. Hasle G. Transport of ixodid ticks and tick-borne pathogens by migratory birds. Front Cell Infect Microbiol. 2013;3:48 pubmed publisher
    Birds, particularly passerines, can be parasitized by Ixodid ticks, which may be infected with tick-borne pathogens, like Borrelia spp., Babesia spp., Anaplasma, Rickettsia/Coxiella, and tick-borne encephalitis virus...
  19. Marcsisin R, Campeau S, Lopez J, Barbour A. Alp, an arthropod-associated outer membrane protein of Borrelia species that cause relapsing fever. Infect Immun. 2012;80:1881-90 pubmed publisher
    ..hermsii antigens but not detectably to native or recombinant Alp...
  20. Chmelar J, Calvo E, Pedra J, Francischetti I, Kotsyfakis M. Tick salivary secretion as a source of antihemostatics. J Proteomics. 2012;75:3842-54 pubmed publisher
    b>Ticks are mostly obligatory blood feeding ectoparasites that have an impact on human and animal health...
  21. Fajs L, Durmisi E, Knap N, Strle F, Avsic Zupanc T. Phylogeographic characterization of tick-borne encephalitis virus from patients, rodents and ticks in Slovenia. PLoS ONE. 2012;7:e48420 pubmed publisher
    ..Genetic variability of TBEV has previously been studied predominantly in rodents and ticks, while information about the variability in patients is scarce...
  22. Montagna M, Sassera D, Epis S, Bazzocchi C, Vannini C, Lo N, et al. "Candidatus Midichloriaceae" fam. nov. (Rickettsiales), an ecologically widespread clade of intracellular alphaproteobacteria. Appl Environ Microbiol. 2013;79:3241-8 pubmed publisher
  23. Ros García A, M ghirbi Y, Hurtado A, Bouattour A. Prevalence and genetic diversity of piroplasm species in horses and ticks from Tunisia. Infect Genet Evol. 2013;17:33-7 pubmed publisher
    ..population of Tunisia were studied using reverse line blot (RLB) hybridization on blood samples and unfed adult ticks collected from apparently healthy horses from three bioclimatic zones in Tunisia...
  24. Gyuranecz M, Denes B, Hornok S, Kovacs P, Horvath G, Jurkovich V, et al. Prevalence of Coxiella burnetii in Hungary: screening of dairy cows, sheep, commercial milk samples, and ticks. Vector Borne Zoonotic Dis. 2012;12:650-3 pubmed publisher
    ..9%). The real-time PCR examination of 5402 ixodid ticks collected from different parts of the country yielded negative results...
  25. Knobel D, Maina A, Cutler S, Ogola E, Feikin D, Junghae M, et al. Coxiella burnetii in humans, domestic ruminants, and ticks in rural western Kenya. Am J Trop Med Hyg. 2013;88:513-8 pubmed publisher
    ..in 2009-2010, in human patients with acute lower respiratory illness, in ruminants following parturition, and in ticks collected from ruminants and domestic dogs. Antibodies against C. burnetii were detected in 30...
  26. Samuels D. Gene regulation in Borrelia burgdorferi. Annu Rev Microbiol. 2011;65:479-99 pubmed publisher
    ..B. burgdorferi also has a c-di-GMP signaling system that regulates the tick side of the enzootic cycle and whose function is only beginning to be appreciated...
  27. Anstead C, Chilton N. Detection of a novel Rickettsia (Alphaproteobacteria: Rickettsiales) in rotund ticks (Ixodes kingi) from Saskatchewan, Canada. Ticks Tick Borne Dis. 2013;4:202-6 pubmed publisher
    ..canadensis and Candidatus Rickettsia tarasevichiae. This novel Rickettsia was found in 60 of the 87 (69%) ticks examined, which included all feeding life cycle stages of I. kingi. Although adult I...
  28. Chomel B. Tick-borne infections in dogs-an emerging infectious threat. Vet Parasitol. 2011;179:294-301 pubmed publisher
  29. Birge J, Sonnesyn S. Powassan virus encephalitis, Minnesota, USA. Emerg Infect Dis. 2012;18:1669-71 pubmed publisher
    ..Since 2008, confirmed cases in Minnesota and Wisconsin have increased. We report a fatal case of POWV encephalitis in Minnesota. POWV infection should be suspected in tick-exposed patients with viral encephalitis...
  30. Silaghi C, Kauffmann M, Passos L, Pfister K, Zweygarth E. Isolation, propagation and preliminary characterisation of Anaplasma phagocytophilum from roe deer (Capreolus capreolus) in the tick cell line IDE8. Ticks Tick Borne Dis. 2011;2:204-8 pubmed publisher
    ..Isolates in cell culture have been obtained from humans, dogs, horses, sheep, and ticks, but no strain from wild ruminants exists in cell culture in Europe...
  31. Milhano N, de Carvalho I, Alves A, Arroube S, Soares J, Rodriguez P, et al. Coinfections of Rickettsia slovaca and Rickettsia helvetica with Borrelia lusitaniae in ticks collected in a Safari Park, Portugal. Ticks Tick Borne Dis. 2010;1:172-7 pubmed publisher
    ..A total of 677 questing ticks including Dermacentor marginatus, Rhipicephalus sanguineus, Ixodes ricinus, Hyalomma lusitanicum, H...
  32. Lu X, Lin X, Wang J, Qin X, Tian J, Guo W, et al. Molecular survey of hard ticks in endemic areas of tick-borne diseases in China. Ticks Tick Borne Dis. 2013;4:288-96 pubmed publisher
    ..To better understand the ticks associated with these infections, we collected hard ticks from animals or around livestock shelters in 29 ..
  33. Ogrzewalska M, Uezu A, Jenkins C, Labruna M. Effect of forest fragmentation on tick infestations of birds and tick infection rates by rickettsia in the Atlantic forest of Brazil. Ecohealth. 2011;8:320-31 pubmed publisher
    ..Atlantic Forest in southeastern Brazil influences the diversity of forest birds and consequently the prevalence of ticks on birds and the rickettsial infection of these ticks...
  34. Yadav P, Cherian S, Zawar D, Kokate P, Gunjikar R, Jadhav S, et al. Genetic characterization and molecular clock analyses of the Crimean-Congo hemorrhagic fever virus from human and ticks in India, 2010-2011. Infect Genet Evol. 2013;14:223-31 pubmed publisher
    ..genomic sequences of four CCHFV isolates derived from two human patients and two pools of Hyalomma anatolicum ticks during the period of this outbreak and the complete S segment sequence of two retrospective human serum samples, ..
  35. Geller J, Nazarova L, Katargina O, Järvekülg L, Fomenko N, Golovljova I. Detection and genetic characterization of relapsing fever spirochete Borrelia miyamotoi in Estonian ticks. PLoS ONE. 2012;7:e51914 pubmed publisher
    During the years 2008-2010 I. ricinus and I. persulcatus ticks were collected from 64 sites in mainland Estonia and on the island Saaremaa. Presence of B. miyamotoi was found in 0.9% (23/2622) of ticks. The prevalence in I...
  36. Nowak Chmura M, Siuda K. Ticks of Poland. Review of contemporary issues and latest research. Ann Parasitol. 2012;58:125-55 pubmed
    The paper presents current knowledge of ticks occurring in Poland, their medical importance, and a review of recent studies implemented in the Polish research centres on ticks and their significance in the epidemiology of transmissible ..
  37. Dantas Torres F, Otranto D. Species diversity and abundance of ticks in three habitats in southern Italy. Ticks Tick Borne Dis. 2013;4:251-5 pubmed publisher
    ..to March 2012 in a forested area in southern Italy to evaluate the species diversity and abundance of free-living ticks in 3 different habitats: (i) a meadow habitat within an enclosure inhabited by roe deer (Capreolus capreolus); (ii)..
  38. Stanneck D, Kruedewagen E, Fourie J, Horak I, Davis W, Krieger K. Efficacy of an imidacloprid/flumethrin collar against fleas, ticks, mites and lice on dogs. Parasit Vectors. 2012;5:102 pubmed publisher
    ..of imidacloprid/flumethrin incorporated in a slow-release matrix collar, against infestations of dogs by fleas, ticks, mites and lice...
  39. Yssouf A, Flaudrops C, Drali R, Kernif T, Socolovschi C, Bérenger J, et al. Matrix-assisted laser desorption ionization-time of flight mass spectrometry for rapid identification of tick vectors. J Clin Microbiol. 2013;51:522-8 pubmed publisher
    A method for rapid species identification of ticks may help clinicians predict the disease outcomes of patients with tick bites and may inform the decision as to whether to administer postexposure prophylactic antibiotic treatment...
  40. Taylor M, Mediannikov O, Raoult D, Greub G. Endosymbiotic bacteria associated with nematodes, ticks and amoebae. FEMS Immunol Med Microbiol. 2012;64:21-31 pubmed publisher
  41. Bardosh K, Waiswa C, Welburn S. Conflict of interest: use of pyrethroids and amidines against tsetse and ticks in zoonotic sleeping sickness endemic areas of Uganda. Parasit Vectors. 2013;6:204 pubmed publisher
    ..The private veterinary market is divided between products only effective against ticks (amidines) and those effective against both ticks and tsetse (pyrethroids)...
  42. Léger E, Vourc h G, Vial L, Chevillon C, McCoy K. Changing distributions of ticks: causes and consequences. Exp Appl Acarol. 2013;59:219-44 pubmed publisher
    Today, we are witnessing changes in the spatial distribution and abundance of many species, including ticks and their associated pathogens...
  43. Socolovschi C, Reynaud P, Kernif T, Raoult D, Parola P. Rickettsiae of spotted fever group, Borrelia valaisiana, and Coxiella burnetii in ticks on passerine birds and mammals from the Camargue in the south of France. Ticks Tick Borne Dis. 2012;3:355-60 pubmed publisher
    b>Ticks are obligate hematophagous arthropods that have a limited mobility, but can be transported over large geographical distances by wild and domestic mammals and birds...
  44. Yang J, Liu Z, Guan G, Liu Q, Li Y, Chen Z, et al. Prevalence of Anaplasma phagocytophilum in ruminants, rodents and ticks in Gansu, north-western China. J Med Microbiol. 2013;62:254-8 pubmed publisher
    ..For adult ticks, 40/598 female ticks (6.7?%) and 26/528 male ticks (4.9?%) were positive...
  45. Miranda J, Portillo A, Oteo J, Mattar S. Rickettsia sp. strain colombianensi (Rickettsiales: Rickettsiaceae): a new proposed Rickettsia detected in Amblyomma dissimile (Acari: Ixodidae) from iguanas and free-living larvae ticks from vegetation. J Med Entomol. 2012;49:960-5 pubmed
    From January to December 2009, 55 Amblyomma dissimile (Koch) ticks removed from iguanas in the municipality of Monteria and 3,114 ticks [458 Amblyomma sp. larvae, 2,636 Rhipicephalus microplus (Canestrini) larvae and 20 Amblyomma sp...
  46. Hornok S, Csörgo T, De La Fuente J, Gyuranecz M, Privigyei C, Meli M, et al. Synanthropic birds associated with high prevalence of tick-borne rickettsiae and with the first detection of Rickettsia aeschlimannii in Hungary. Vector Borne Zoonotic Dis. 2013;13:77-83 pubmed publisher
    The aim of this study was to analyze synanthropic birds as risk factors for introducing ticks and tick-borne pathogens into human settlements, with an emphasis on rickettsiae. Altogether 184 subadult ticks were found on 5846 birds...
  47. Trotta M, Nicetto M, Fogliazza A, Montarsi F, Caldin M, Furlanello T, et al. Detection of Leishmania infantum, Babesia canis, and rickettsiae in ticks removed from dogs living in Italy. Ticks Tick Borne Dis. 2012;3:294-7 pubmed publisher
    ..Babesia spp., and Hepatozoon spp. by molecular methods in ticks (n=91) removed from dogs with clinical signs and laboratory abnormalities compatible with tick-borne diseases (n=..
  48. Silaghi C, Woll D, Hamel D, Pfister K, Mahling M, Pfeffer M. Babesia spp. and Anaplasma phagocytophilum in questing ticks, ticks parasitizing rodents and the parasitized rodents--analyzing the host-pathogen-vector interface in a metropolitan area. Parasit Vectors. 2012;5:191 pubmed publisher
    ..and Anaplasma phagocytophilum in restored areas in both questing and host-attached Ixodes ricinus and Dermacentor reticulatus and their small mammalian hosts...
  49. Clark K. Anaplasma phagocytophilum in small mammals and ticks in northeast Florida. J Vector Ecol. 2012;37:262-8 pubmed publisher
    ..The aim of this study was to determine if A. phagocytophilum is present in small mammals and ticks in northeast Florida...
  50. Rudenko N, Golovchenko M, Grubhoffer L, Oliver J. Updates on Borrelia burgdorferi sensu lato complex with respect to public health. Ticks Tick Borne Dis. 2011;2:123-8 pubmed publisher
    ..Recently, the definition of the disease has also changed. What was not considered Lyme borreliosis before might be now...
  51. Randolph S. Transmission of tick-borne pathogens between co-feeding ticks: Milan Labuda's enduring paradigm. Ticks Tick Borne Dis. 2011;2:179-82 pubmed publisher
    ..tick feeding sites, bearing infective virions and providing a transport route for the virus between co-feeding ticks independent of a systemic viraemia...
  52. Temeyer K, Tuckow A, Brake D, Li A, Perez de Leon A. Acetylcholinesterases of blood-feeding flies and ticks. Chem Biol Interact. 2013;203:319-22 pubmed publisher
    ..Organophosphate pesticides (OPs) are widely used to control blood-feeding arthropods, including biting flies and ticks. However, resistance to OPs in pests affecting animal and human health has compromised control efficacy...
  53. Reuben Kaufman W. Ticks: physiological aspects with implications for pathogen transmission. Ticks Tick Borne Dis. 2010;1:11-22 pubmed publisher
    b>Ticks have attracted a great deal of scientific attention primarily because of their role as vectors of numerous pathogens...