Summary: The family Erinaceidae, in the order INSECTIVORA. Most are true hedgehogs possessing a coat of spines and a very short tail. Those members of the family found in Southeast Asia (moonrats or gymnures) have normal body hair and a long tail.

Top Publications

  1. Seddon J, Santucci F, Reeve N, Hewitt G. DNA footprints of European hedgehogs, Erinaceus europaeus and E. concolor: Pleistocene refugia, postglacial expansion and colonization routes. Mol Ecol. 2001;10:2187-98 pubmed
    European hedgehogs, Erinaceus europaeus and E. concolor, are among the many European plant and animal taxa that have been subjected to cyclical restriction to glacial refugia and interglacial expansion...
  2. Bolfíková B, Hulva P. Microevolution of sympatry: landscape genetics of hedgehogs Erinaceus europaeus and E. roumanicus in Central Europe. Heredity (Edinb). 2012;108:248-55 pubmed publisher
    ..to assess the distribution patterns, population structure, demography and landscape genetics for the hedgehogs Erinaceus europaeus and Erinaceus roumanicus in a transect of the mid-European zone of sympatry. E...
  3. Pantchev N, Hofmann T. Notoedric mange caused by Notoedres cati in a pet African pygmy hedgehog (Atelerix albiventris). Vet Rec. 2006;158:59-60 pubmed
  4. Schauder S, Kirsch Nietzki M, Wegener S, Switzer E, Qadripur S. [From hedgehogs to men. Zoophilic dermatophytosis caused by Trichophyton erinacei in eight patients]. Hautarzt. 2007;58:62-7 pubmed
    ..The other caretakers who wore gloves presented with typical ringworm on the arms, the big toe, the back, the abdomen, and the thighs. Their typical clinical features led to an early diagnosis and treatment...
  5. Monecke S, Gavier Widen D, Mattsson R, Rangstrup Christensen L, Lazaris A, Coleman D, et al. Detection of mecC-positive Staphylococcus aureus (CC130-MRSA-XI) in diseased European hedgehogs (Erinaceus europaeus) in Sweden. PLoS ONE. 2013;8:e66166 pubmed publisher
    ..aureus (ST130-MRSA-XI) and the lesions related to the infection in two diseased free-ranging European hedgehogs (Erinaceus europaeus). One was found dead in 2003 in central Sweden, and suffered from S. aureus septicaemia...
  6. Dopke C, Fehr M, Thiele A, Pohlenz J, Wohlsein P. Morphological and immunohistochemical characterization of spontaneous mammary tumours in European hedgehogs (Erinaceus europaeus). J Comp Pathol. 2007;137:22-29 pubmed publisher
    Mammary tumour samples (11 surgical and five post-mortem) from 16 adult European hedgehogs submitted between 1980 and 2004 were examined...
  7. Behr M. Hedgehog zoonoses. Emerg Infect Dis. 2005;11:1146; author reply 1146 pubmed
  8. Ellis C, Mori M. Skin diseases of rodents and small exotic mammals. Vet Clin North Am Exot Anim Pract. 2001;4:493-542 pubmed
    ..Veterinarians are encouraged always to apply the same diagnostic protocols used to work up skin problems in dogs and cats when presented with an exotic pet with a dermatologic disease...
  9. Pfäffle M, Petney T, Skuballa J, Taraschewski H. Comparative population dynamics of a generalist (Ixodes ricinus) and specialist tick (I. hexagonus) species from European hedgehogs. Exp Appl Acarol. 2011;54:151-64 pubmed publisher
    ..ricinus with the nest-dwelling hedgehog specialist, I. hexagonus. Both species were collected from hedgehogs from a naturally infested experimental population between 2006 and 2008...

More Information


  1. Nikaido M, Cao Y, Harada M, Okada N, Hasegawa M. Mitochondrial phylogeny of hedgehogs and monophyly of Eulipotyphla. Mol Phylogenet Evol. 2003;28:276-84 pubmed
    ..mitochondrial protein analyses used a simple model that did not consider site-heterogeneity, and Erinaceoidea (hedgehogs and moonrats) was placed at the basal eutherian position that is separated from Soricoidea (shrews) and ..
  2. Epe C, Coati N, Schnieder T. [Results of parasitological examinations of faecal samples from horses, ruminants, pigs, dogs, cats, hedgehogs and rabbits between 1998 and 2002]. Dtsch Tierarztl Wochenschr. 2004;111:243-7 pubmed
    The results of coproscopical examinations in horses, ruminants, pigs, dogs, cats, hedgehogs and rabbits between 1998 and 2002 are presented. In 4399 samples from horses 37.4% stages of strongylids, 1.4% anoplocephalids, 1...
  3. Woodward D, Khakhria R, Johnson W. Human salmonellosis associated with exotic pets. J Clin Microbiol. 1997;35:2786-90 pubmed
    ..human salmonellosis associated with exposure to exotic pets including iguanas, pet turtles, sugar gliders, and hedgehogs was observed in Canada...
  4. Rosen T, Jablon J. Infectious threats from exotic pets: dermatological implications. Dermatol Clin. 2003;21:229-36 pubmed
  5. Riley P, Chomel B. Hedgehog zoonoses. Emerg Infect Dis. 2005;11:1-5 pubmed
    Exotic pets, including hedgehogs, have become popular in recent years among pet owners, especially in North America...
  6. Poglayen G, Giannetto S, Scala A, Garippa G, Capelli G, Scaravelli D, et al. Helminths found in hedgehogs (Erinaceus europaeus) in three areas of Italy. Vet Rec. 2003;152:22-4 pubmed
  7. Passey S, Pellegrin S, Mellor H. What is in a filopodium? Starfish versus hedgehogs. Biochem Soc Trans. 2004;32:1115-7 pubmed
    ..Specifically, we highlight the differences between the filopodial extensions induced by the Rho GTPases Cdc42 and Rif...
  8. Berggren K, Ellegren H, Hewitt G, Seddon J. Understanding the phylogeographic patterns of European hedgehogs, Erinaceus concolor and E. europaeus using the MHC. Heredity (Edinb). 2005;95:84-90 pubmed
    ..in the hedgehog using two loci of the major histocompatibility complex (MHC), isolated for the first time in hedgehogs. These genes show long persistence times and high polymorphism in many species because of the actions of ..
  9. Dakubo G, Wallace V. Hedgehogs and retinal ganglion cells: organizers of the mammalian retina. Neuroreport. 2004;15:479-82 pubmed
    ..In this review we will discuss the role of Hh signals from retinal ganglion cells (RGCs), the projection neurons of the retina, on proliferation, differentiation and lamination in the neural retina...
  10. Corman V, Kallies R, Philipps H, Göpner G, Müller M, Eckerle I, et al. Characterization of a novel betacoronavirus related to middle East respiratory syndrome coronavirus in European hedgehogs. J Virol. 2014;88:717-24 pubmed publisher
    ..their hosts, we sought to investigate the closest sister taxon to bats, the Eulipotyphla, and screened European hedgehogs (Erinaceus europaeus) from Germany for CoV by nested reverse transcriptase PCR...
  11. Handeland K, Refsum T, Johansen B, Holstad G, Knutsen G, Solberg I, et al. Prevalence of Salmonella typhimurium infection in Norwegian hedgehog populations associated with two human disease outbreaks. Epidemiol Infect. 2002;128:523-7 pubmed
    Faecal carriage of salmonella was investigated in 320 hedgehogs from Moss municipality in south-eastern Norway, Askøy, Bergen and Os municipalities in central-western Norway, and five municipalities in south-western and central Norway...
  12. Allison N, Chang T, Steele K, Hilliard J. Fatal herpes simplex infection in a pygmy African hedgehog (Atelerix albiventris). J Comp Pathol. 2002;126:76-8 pubmed
    ..To our knowledge, this is the first report of herpes infection in the African hedgehog and the first time herpes simplex has been identified as a cause of disease in insectivores...
  13. Skuballa J, Oehme R, Hartelt K, Petney T, Bucher T, Kimmig P, et al. European Hedgehogs as Hosts for Borrelia spp., Germany. Emerg Infect Dis. 2007;13:952-3 pubmed
  14. Dyachenko V, Kuhnert Y, Schmaeschke R, Etzold M, Pantchev N, Daugschies A. Occurrence and molecular characterization of Cryptosporidium spp. genotypes in European hedgehogs (Erinaceus europaeus L.) in Germany. Parasitology. 2010;137:205-16 pubmed publisher
    Juvenile hedgehogs having insufficient body weight are often brought for overwintering to hedgehog rehabilitation centres...
  15. Cirak V, Senlik B, Aydogdu A, Selver M, Akyol V. Helminth parasites found in hedgehogs (Erinaceus concolor) from Turkey. Prev Vet Med. 2010;97:64-6 pubmed publisher
    ..surgeons due to growing interest in this animal species among pet owners and an increase in cases of rescued hedgehogs requiring veterinary care...
  16. Mizgajska Wiktor H, Jarosz W, Piłacińska B, Dziemian S. [Helminths of hedgehogs, Erinaceus europaeus and E. roumanicus from Pozna? region, Poland--coprological study]. Wiad Parazytol. 2010;56:329-32 pubmed
    Fecal samples from the hedgehogs, Erinaceus europaeus (15 samples) and E. roumanicus (44 samples) collected in the Pozna? region of Poland were examined. Endoparasites were isolated using Sheather's flotation technique...
  17. Kim D, Oh D, Ahn K, Shin S. An outbreak of Caparinia tripilis in a colony of African pygmy hedgehogs (Atelerix albiventris) from Korea. Korean J Parasitol. 2012;50:151-6 pubmed publisher
    ..2010, dermatitis characterized by scale and self-trauma due to puritis was recognized in a group of 22 four-toed hedgehogs (Atelerix albiventris Wagner, 1841) from a local pet shop in Gwangju, Korea...
  18. Gern L, Rouvinez E, Toutoungi L, Godfroid E. Transmission cycles of Borrelia burgdorferi sensu lato involving Ixodes ricinus and/or I. hexagonus ticks and the European hedgehog, Erinaceus europaeus, in suburban and urban areas in Switzerland. Folia Parasitol (Praha). 1997;44:309-14 pubmed
    ..To investigate whether hedgehogs are reservoirs for B...
  19. Skuballa J, Petney T, Pfäffle M, Oehme R, Hartelt K, Fingerle V, et al. Occurrence of different Borrelia burgdorferi sensu lato genospecies including B. afzelii, B. bavariensis, and B. spielmanii in hedgehogs (Erinaceus spp.) in Europe. Ticks Tick Borne Dis. 2012;3:8-13 pubmed publisher
    In order to determine whether European hedgehogs (Erinaceus europaeus and E...
  20. Liesegang A, Lehmann M. [Frequency of diseases and death in hedgehogs]. Schweiz Arch Tierheilkd. 2003;145:589-91 pubmed
  21. Douady C, Chatelier P, Madsen O, de Jong W, Catzeflis F, Springer M, et al. Molecular phylogenetic evidence confirming the Eulipotyphla concept and in support of hedgehogs as the sister group to shrews. Mol Phylogenet Evol. 2002;25:200-9 pubmed
    ..included hedgehogs, moles, shrews, solenodons, golden moles, tenrecs, flying lemurs, tree shrews, and elephant shrews in ..
  22. Takahashi Y, Sano A, Takizawa K, Fukushima K, Miyaji M, Nishimura K. The epidemiology and mating behavior of Arthroderma benhamiae var. erinacei in household four-toed hedgehogs (Atelerix albiventris) in Japan. Nihon Ishinkin Gakkai Zasshi. 2003;44:31-8 pubmed
    ..The fungus was isolated only from the quills of four-toed hedgehogs (7/18; 39%) from Kanto to Kyushu regions...
  23. Done L, Deem S, Fiorello C. Surgical and medical management of a uterine spindle cell tumor in an African hedgehog (Atelerix albiventris). J Zoo Wildl Med. 2007;38:601-3 pubmed
    ..Hematuria did not reoccur, and the hedgehog lived for another 19 mo until she died from an oral squamous cell carcinoma. To date, this is the first report of a uterine spindle cell tumor in an African hedgehog. ..
  24. Gibson C, Parry N, Jakowski R, Eshar D. Anaplastic astrocytoma in the spinal cord of an African pygmy hedgehog (Atelerix albiventris). Vet Pathol. 2008;45:934-8 pubmed publisher
    ..A diagnosis of anaplastic astrocytoma was confirmed using immunohistochemical stains that were positive for glial fibrillary acidic protein and S100. ..
  25. Takada R. [Functional significance of lipid modification of secreted signaling proteins]. Seikagaku. 2007;79:888-92 pubmed
  26. Künzle H. Thalamo-striatal projections in the hedgehog tenrec. Brain Res. 2006;1100:78-92 pubmed
    ..The medial and intralaminar nuclei also projected heavily upon the olfactory tubercle. Differential innervation patterns were noted in the polymorphous layer, the deep and the superficial molecular layer. ..
  27. Chemkhi J, Souguir H, Ali I, Driss M, Guizani I, Guerbouj S. Natural infection of Algerian hedgehog, Atelerix algirus (Lereboullet 1842) with Leishmania parasites in Tunisia. Acta Trop. 2015;150:42-51 pubmed publisher
    ..In order to explore the role of hedgehogs as potential reservoirs of leishmaniasis, specimens (N=6) were captured during July-November period in 2011-2013 ..
  28. Barchan D, Ovadia M, Kochva E, Fuchs S. The binding site of the nicotinic acetylcholine receptor in animal species resistant to alpha-bungarotoxin. Biochemistry. 1995;34:9172-6 pubmed
    ..abstract truncated at 250 words)..
  29. Ogihara K, Suzuki K, Madarame H. Primary Histiocytic Sarcoma of the Brain in an African Hedgehog (Atelerix albiventris). J Comp Pathol. 2017;157:241-245 pubmed publisher
    ..This report represents the first documentation of primary CNS HS in this species. Primary CNS HS should be considered as a differential diagnoses for hedgehogs that present with neurological signs of WHS.
  30. Saengtienchai A, Ikenaka Y, Bortey Sam N, Jermnark U, Mizukawa H, Kawai Y, et al. The African hedgehog (Atelerix albiventris): Low phase I and phase II metabolism activities. Comp Biochem Physiol C Toxicol Pharmacol. 2016;190:38-47 pubmed publisher
    ..To elucidate the ability of hedgehogs to metabolize xenobiotics, the animals were exposed to polycyclic aromatic hydrocarbon, pyrene...
  31. King P, Guasti L, Laufer E. Hedgehog signalling in endocrine development and disease. J Endocrinol. 2008;198:439-50 pubmed publisher
    ..In this review, we provide an update on recent findings in the field of vertebrate Hh signalling and also describe contributions of Hh signalling to the development, maintenance and pathology of endocrine tissues. ..
  32. Künzle H, Radtke Schuller S. Hippocampal fields in the hedgehog tenrec. Their architecture and major intrinsic connections. Neurosci Res. 2001;41:267-91 pubmed
    ..The perisubicular region, located medially adjacent to the dorsal subiculum may be equivalent to the rat's presubiculum; evidence for the presence of a parasubiculum was rather weak. ..
  33. Abarca M, Castella G, Martorell J, Cabañes F. Trichophyton erinacei in pet hedgehogs in Spain: Occurrence and revision of its taxonomic status. Med Mycol. 2017;55:164-172 pubmed publisher
    b>Hedgehogs have increased in popularity as pets in Spain but there are no data of infection rates of this exotic animal with dermatophytes in our country...
  34. Wen X, He J, Zhang X, Zhao L, Du S. Localization of Smad4 in the ovary of the European hedgehog (Erinaceus europaeus L.). Acta Histochem. 2011;113:382-6 pubmed publisher
    ..In the corpora lutea, the immunostaining for Smad4 was very intense. These results suggested that Smad signal transduction may play an important role in folliculogenesis and conceivably may participate in subsequent pregnancy. ..
  35. Künzle H, Radtke Schuller S. The subrhinal paleocortex in the hedgehog tenrec: a multiarchitectonic characterization and an analysis of its connections with the olfactory bulb. Anat Embryol (Berl). 2000;202:491-506 pubmed
    ..The bulbar projections to the PCx were very extensive and almost exclusively ipsilateral. The laterality of the projection is similar to that in higher mammals, but differs from that in the erinaceous hedgehog. ..
  36. Raue K, Heuer L, Böhm C, Wolken S, Epe C, Strube C. 10-year parasitological examination results (2003 to 2012) of faecal samples from horses, ruminants, pigs, dogs, cats, rabbits and hedgehogs. Parasitol Res. 2017;116:3315-3330 pubmed publisher
    The results of coproscopical examinations in domestic animals and hedgehogs carried out as routine diagnostics in the years 2003 to 2012 at the Institute for Parasitology, University of Veterinary Medicine Hannover, Germany, are ..
  37. Swift N, Hsiung B, Kennedy E, Tan K. Dynamic impact testing of hedgehog spines using a dual-arm crash pendulum. J Mech Behav Biomed Mater. 2016;61:271-282 pubmed publisher
    ..of roughly 130 keratin spines were mounted vertically in thin substrates to mimic the natural spine layout on hedgehogs. A weighted crash pendulum was employed to induce and measure the effects of repeated collisions against samples,..
  38. Bitam I, Rolain J, Nicolas V, Tsai Y, Parola P, Gundi V, et al. A multi-gene analysis of diversity of Bartonella detected in fleas from Algeria. Comp Immunol Microbiol Infect Dis. 2012;35:71-6 pubmed publisher
    ..5%) of 204 fleas from Algeria collected from 26 rodents and 7 hedgehogs. Bartonella elizabethae and B. clarridgeiae were detected in the fleas collected on hedgehogs...
  39. Evans E, Souza M. Advanced diagnostic approaches and current management of internal disorders of select species (rodents, sugar gliders, hedgehogs). Vet Clin North Am Exot Anim Pract. 2010;13:453-69 pubmed publisher
    African pygmy and European hedgehogs, sugar gliders, and rodents such as rats, mice, gerbils, hamsters, guinea pigs, and chinchillas are becoming increasingly popular as pets in the United States, and more practitioners are being asked ..
  40. Han J, Lee S, Jang H, Kim J, Na K. Isolation of Staphylococcus simulans from dermatitis in a captive African pygmy hedgehog. J Zoo Wildl Med. 2011;42:277-80 pubmed
    ..simulans by polymerase chain reaction amplification and direct sequencing targeted to the 16S ribosomal RNA gene. This report is the first to show that S. simulans could be related to the dermatitis of hedgehogs.
  41. Hummel T, Attix S, Gunning D, Zipursky S. Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genes. Neuron. 2002;33:193-203 pubmed
    ..We propose that the spatiotemporal control of glial cell migration plays a critical role in determining the directionality of R cell axon outgrowth. ..
  42. Facciolo R, Alo R, Canonaco M, Franzoni M. Early phylogenetic value of the major GABA(A) receptor subunit mRNAs in the telencephalon. Exp Brain Res. 2002;142:504-11 pubmed
  43. Fisher P. Exotic mammal renal disease: causes and clinical presentation. Vet Clin North Am Exot Anim Pract. 2006;9:33-67 pubmed
    ..Anatomic pathology at the gross and microscopic level is reviewed, as is disease pathophysiology unique to the species under discussion. ..
  44. Tepass U, Godt D, Winklbauer R. Cell sorting in animal development: signalling and adhesive mechanisms in the formation of tissue boundaries. Curr Opin Genet Dev. 2002;12:572-82 pubmed
    ..Further, several examples demonstrate that cell sorting in vivo can be driven by Eph/ephrin signalling and by the differential expression of cadherins that modulate cell adhesion and motility. ..
  45. Miwa Y, Sladky K. Small Mammals: Common Surgical Procedures of Rodents, Ferrets, Hedgehogs, and Sugar Gliders. Vet Clin North Am Exot Anim Pract. 2016;19:205-44 pubmed publisher
  46. D Havé H, Scheirs J, Covaci A, Schepens P, Verhagen R, De Coen W. Nondestructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): III. Hair as an indicator of endogenous organochlorine compound concentrations. Environ Toxicol Chem. 2006;25:158-67 pubmed
    ..5 ng/g liver wet weight. Compared to results with other mammalian wildlife, the present results indicate that hedgehogs may accumulate considerable concentrations of organochlorine compounds...
  47. Gal J, Landauer K, Palade E, Ivaskevics K, Rusvai M, Demeter Z. Squamous cell carcinoma and consequent otitis in a Long-eared Hedgehog (Hemiechinus auritus)--case report. Acta Vet Hung. 2009;57:69-73 pubmed publisher
    ..Using routine haematoxylin and eosin and immunohistochemical staining techniques, the tumour was identified as a squamous cell carcinoma. This work constitutes the first description of such a tumour in a Long-eared Hedgehog. ..
  48. Henson M, Madden V, Rask Andersen H, Henson O. Smooth muscle in the annulus fibrosus of the tympanic membrane in bats, rodents, insectivores, and humans. Hear Res. 2005;200:29-37 pubmed
    ..The smooth muscle in all species studied appears to form a rim of contractile elements for the pars tensa. This arrangement suggests a role in controlling blood flow and/or creating and maintaining tension on the tympanic membrane. ..
  49. Bhatia B, Potts C, Guldal C, Choi S, Korshunov A, Pfister S, et al. Hedgehog-mediated regulation of PPAR? controls metabolic patterns in neural precursors and shh-driven medulloblastoma. Acta Neuropathol. 2012;123:587-600 pubmed publisher
    ..These findings emphasize the value of PPAR? downstream of Shh as a global therapeutic target in hedgehog-dependent and/or Rb-inactivated tumors. ..
  50. Khoii M, Howerth E, Burns R, Carmichael K, Gyimesi Z. Spontaneous neoplasia in four captive greater hedgehog tenrecs (Setifer setosus). J Zoo Wildl Med. 2008;39:392-7 pubmed
    ..This is the first report of neoplasia in greater hedgehog tenrecs. ..
  51. Wilson C, Stainier D. Vertebrate Hedgehog signaling: cilia rule. BMC Biol. 2010;8:102 pubmed publisher
    ..Recent work, including a study in BMC Biology, demonstrates that Hh signals through the cilium in zebrafish, clarifying the evolution of Hh signal transduction. See research article: http://www.biomedcentral.com/1741-7007/8/65...
  52. Künzle H, Radtke Schuller S. Cortical connections of the claustrum and subjacent cell groups in the hedgehog tenrec. Anat Embryol (Berl). 2001;203:403-15 pubmed
    ..The unusual features described in tenrec were discussed with respect to similar organizations in other mammals with poorly differentiated brains and compared with embryonic brains of mammals with more differentiated brains...
  53. Ozparlak H, Celik I, Sur E, Ozaydin T, Arslan A. A study of peripheral blood in hedgehogs in Turkey. J Zoo Wildl Med. 2011;42:392-8 pubmed
    ..activity of some leukocyte types, and enzymatic positivity percentages of peripheral blood lymphocytes in two hedgehogs species, Hemiechinus auritus, the long-eared hedgehog, and Erinaceus concolor, the southern white-breasted ..
  54. Speck S, Perseke L, Petney T, Skuballa J, Pfäffle M, Taraschewski H, et al. Detection of Rickettsia helvetica in ticks collected from European hedgehogs (Erinaceus europaeus, Linnaeus, 1758). Ticks Tick Borne Dis. 2013;4:222-6 pubmed publisher
    ..European hedgehogs (Erinaceus europaeus) are often heavily infested by tick and flea species that are known to harbor and transmit ..
  55. He K, Chen J, Gould G, Yamaguchi N, Ai H, Wang Y, et al. An estimation of Erinaceidae phylogeny: a combined analysis approach. PLoS ONE. 2012;7:e39304 pubmed publisher
    Erinaceidae is a family of small mammals that include the spiny hedgehogs (Erinaceinae) and the silky-furred moonrats and gymnures (Galericinae)...
  56. Kiecker C, Lumsden A. Hedgehog signaling from the ZLI regulates diencephalic regional identity. Nat Neurosci. 2004;7:1242-9 pubmed
    ..We show that, through the release of Shh, the ZLI functions as a local signaling center that regulates the acquisition of identity for these important diencephalic regions...
  57. Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, Pfaff S. Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron. 1999;23:675-87 pubmed
    ..Thus, MNs actively suppress interneuron genetic programs to establish their identity...
  58. Laatamna A, Wagnerová P, Sak B, Kvetonova D, Aissi M, Rost M, et al. Equine cryptosporidial infection associated with Cryptosporidium hedgehog genotype in Algeria. Vet Parasitol. 2013;197:350-3 pubmed publisher
    ..These findings support the potential role of infected horses in sylvatic-domestic transmission of Cryptosporidium. ..
  59. Sollertinskaia T. [Regulating effect of exogenous vasopressin on the autonomic functions and higher nervous activity of the hedgehog Erinateus auritus exposed to high temperature of the environment]. Zh Evol Biokhim Fiziol. 2002;38:76-82 pubmed
  60. Takahashi Y, Haritani K, Sano A, Takizawa K, Fukushima K, Miyaji M, et al. An isolate of Arthroderma benhamiae with Trichophyton mentagrophytes var. erinacei anamorph isolated from a four-toed hedgehog (Atelerix albiventris) in Japan. Nihon Ishinkin Gakkai Zasshi. 2002;43:249-55 pubmed
    ..mentagrophytes var. erinacei (DDBJ/EMBL/GenBank accession numbers Z97996 and Z97997) by more than 99.7%. Therefore, our case is the first isolation of A. benhamiae with T. mentagrophytes var. erinacei anamorph in Japan...
  61. Petrova E, Rios Esteves J, Ouerfelli O, Glickman J, Resh M. Inhibitors of Hedgehog acyltransferase block Sonic Hedgehog signaling. Nat Chem Biol. 2013;9:247-9 pubmed publisher
    ..A target-oriented high-throughput screen was used to identify small-molecule inhibitors of Hhat. In cells, these Hhat inhibitors specifically block Shh palmitoylation and inhibit autocrine and paracrine Shh signaling. ..
  62. de Sousa R, Edouard Fournier P, Santos Silva M, Amaro F, Bacellar F, Raoult D. Molecular detection of Rickettsia felis, Rickettsia typhi and two genotypes closely related to Bartonella elizabethae. Am J Trop Med Hyg. 2006;75:727-31 pubmed
    ..Our findings emphasize the potential risk of flea-transmitted infections in mainland Portugal and the Madeira archipelago, and extend our knowledge of the potential flea vectors of human pathogens...
  63. Pignon C, Mayer J. Zoonoses of ferrets, hedgehogs, and sugar gliders. Vet Clin North Am Exot Anim Pract. 2011;14:533-49, vii pubmed publisher
    ..This article reviews zoonoses that occur naturally in ferrets, hedgehogs, and sugar gliders, discussing the occurrence and clinical symptoms of these diseases in humans.
  64. Lawn R, Schwartz K, Patthy L. Convergent evolution of apolipoprotein(a) in primates and hedgehog. Proc Natl Acad Sci U S A. 1997;94:11992-7 pubmed
    ..This expressed gene is confined to a subset of primates. Although most mammals lack apo(a), hedgehogs produce an apo(a)-like protein composed of highly repeated copies of a plasminogen kringle three-like domain, ..
  65. Vermeulen F, Covaci A, D Havé H, Van den Brink N, Blust R, De Coen W, et al. Accumulation of background levels of persistent organochlorine and organobromine pollutants through the soil-earthworm-hedgehog food chain. Environ Int. 2010;36:721-7 pubmed publisher
    ..POPs were measured in soil and earthworms collected in grassland and open woodland and in hair and blood of hedgehogs foraging in two parks containing these habitats. Despite background concentrations in soil (ranging from 1...
  66. Dierenfeld E. Feeding behavior and nutrition of the african pygmy hedgehog (Atelerix albiventris). Vet Clin North Am Exot Anim Pract. 2009;12:335-7, x pubmed publisher
    ..wide global distribution and popularity as pets, little is known concerning specific nutritional requirements of hedgehogs. They inhabit a wide variety of environments from desert to temperate forest, and they display flexible and ..
  67. Cousquer G. Analysis of tracheal sputum for diagnosing and monitoring verminous pneumonia in hedgehogs (Erinaceus europaeus). Vet Rec. 2004;154:332-3 pubmed
  68. D Havé H, Scheirs J, Mubiana V, Verhagen R, Blust R, De Coen W. Nondestructive pollution exposure assessment in the European hedgehog (Erinaceus europaeus): I. Relationships between concentrations of metals and arsenic in hair, spines, and soil. Environ Toxicol Chem. 2005;24:2356-64 pubmed
    ..In the present study we assessed metal exposure of hedgehogs (Erinaceus europaeus) by investigating relationships between concentrations of metals (Ag, Al, Cd, Co, Cr, Cu, ..
  69. Zou Y, Wang Q, Fu Z, Liu P, Jin H, Yang H, et al. Detection of spotted fever group Rickettsia in Haemaphysalis longicornis from Hebei Province, China. J Parasitol. 2011;97:960-2 pubmed publisher
    ..The new strain, named Candidatus Rickettsia hebeiii, appears to represent a distinct lineage and could constitute a new species with a minimum prevalence of about 0.7% in H. longicornis from Hebei Province, China...
  70. Manfredi M, Dini V, Piacenza S, Genchi C. Tick species parasitizing people in an area endemic for tick-borne diseases in north-western Italy. Parassitologia. 1999;41:555-60 pubmed
    ..bursa, R. sanguineus, R. turanicus). I. ricinus and R. sanguineus were the most abundant species. I. ricinus was recorded more frequently from ruminants particularly roe deer, while R. sanguineus was found to be associated with the dog...
  71. Briñón J, Weruaga E, Crespo C, Porteros A, Arevalo R, Aijon J, et al. Calretinin-, neurocalcin-, and parvalbumin-immunoreactive elements in the olfactory bulb of the hedgehog (Erinaceus europaeus). J Comp Neurol. 2001;429:554-70 pubmed
    ..By contrast, the functionally important role of the main olfactory system in the hedgehog is accompanied by a more complex organization, which is reflected in an increased diversity of calcium-buffering systems...
  72. Boffelli D, Cheng J, Rubin E. Convergent evolution in primates and an insectivore. Genomics. 2004;83:19-23 pubmed
    ..The similar structural domains shared by the hedgehog and primate LPA indicate that they were formed by a unique molecular mechanism involving the convergent evolution of paralogous genes in these distant species...
  73. Benoit Biancamano M, D Anjou M, Girard C, Langlois I. Rib osteoblastic osteosarcoma in an African hedgehog (Atelerix albiventris). J Vet Diagn Invest. 2006;18:415-8 pubmed
    ..To the authors' knowledge, this is the first report of an osteoblastic osteosarcoma on the thoracic wall of an African hedgehog, as well as the first report of the use of helical computed tomography in that species...
  74. Hallam S, Mzilikazi N. Heterothermy in the southern African hedgehog, Atelerix frontalis. J Comp Physiol B. 2011;181:437-45 pubmed publisher
    ..In this study, we continuously measured body temperature of southern African hedgehogs (Atelerix frontalis) between April and August 2009 (-10°C < T (a) < 43°C), kept under semi-captive ..
  75. Abramochkin A, Sukhova G, Rozenshtraukh L. [Peculiarities of regulation of cardiac function in some mammals]. Kardiologiia. 2006;46:50-3 pubmed
    ..It is suggested that these animals have unique nervous regulation of cardiac action, principally different from that of other mammals, which do not require parasympathetic regulation of ventricles...
  76. Mikaelian I, Reavill D, Practice A. Spontaneous proliferative lesions and tumors of the uterus of captive African hedgehogs (Atelerix albiventris). J Zoo Wildl Med. 2004;35:216-20 pubmed
    Fifteen captive female African hedgehogs (Atelerix albiventris), 3- to 5-yr-old, were diagnosed with proliferative uterine lesions (n = 28)...
  77. Strahle U, Rastegar S. Conserved non-coding sequences and transcriptional regulation. Brain Res Bull. 2008;75:225-30 pubmed publisher
    ..Our data suggest that conservation of sequence does not necessarily imply a conserved function in other vertebrates...
  78. Hofmannová L, Hauptman K, Huclová K, Kvetonova D, Sak B, Kvac M. Cryptosporidium erinacei and C. parvum in a group of overwintering hedgehogs. Eur J Protistol. 2016;56:15-20 pubmed publisher
    This study describes cryptosporidiosis in an overwintering group of 15 European hedgehogs (Erinaceus europaeus), comprising 3 adults and 12 juveniles...
  79. Nikaido M, Kawai K, Cao Y, Harada M, Tomita S, Okada N, et al. Maximum likelihood analysis of the complete mitochondrial genomes of eutherians and a reevaluation of the phylogeny of bats and insectivores. J Mol Evol. 2001;53:508-16 pubmed
    ..Recent phylogenetic controversy over the polyphyly of microbats, the monophyly of rodents, and the position of hedgehogs is also examined.
  80. Moussaif M, Sze J. Intraflagellar transport/Hedgehog-related signaling components couple sensory cilium morphology and serotonin biosynthesis in Caenorhabditis elegans. J Neurosci. 2009;29:4065-75 pubmed publisher
    ..elegans under stress and stress recovery...
  81. Anacker C, Cattaneo A, Luoni A, Musaelyan K, Zunszain P, Milanesi E, et al. Glucocorticoid-related molecular signaling pathways regulating hippocampal neurogenesis. Neuropsychopharmacology. 2013;38:872-83 pubmed publisher
    ..In conclusion, our data demonstrate novel molecular signaling pathways that are regulated by glucocorticoids in vitro, in human hippocampal progenitor cells, and by stress in vivo, in the rat hippocampus...