papio anubis

Summary

Summary: A species of baboon in the family CERCOPITHECIDAE with a somewhat different social structure than PAPIO HAMADRYAS. They inhabit several areas in Africa south of the Sahara.

Top Publications

  1. Gashaw I, Hastings J, Jackson K, Winterhager E, Fazleabas A. Induced endometriosis in the baboon (Papio anubis) increases the expression of the proangiogenic factor CYR61 (CCN1) in eutopic and ectopic endometria. Biol Reprod. 2006;74:1060-6 pubmed
    ..We have chosen the baboon model (Papio anubis) of induced endometriosis to clarify whether CYR61 mRNA upregulation is predisposed to an inappropriately ..
  2. Wall C, Vinyard C, Johnson K, Williams S, Hylander W. Phase II jaw movements and masseter muscle activity during chewing in Papio anubis. Am J Phys Anthropol. 2006;129:215-24 pubmed
    ..motion and relative activity of the masseter and temporalis muscles during phase I and II movements in Papio anubis. We test whether significant muscle activity and, by inference, occlusal force occurs during phase II movement...
  3. Cordoba Chacon J, Gahete M, Castaño J, Kineman R, Luque R. Homologous and heterologous in vitro regulation of pituitary receptors for somatostatin, growth hormone (GH)-releasing hormone, and ghrelin in a nonhuman primate (Papio anubis). Endocrinology. 2012;153:264-72 pubmed publisher
    ..GH release, directly and specifically, in primary pituitary cultures from a nonhuman primate (baboons, Papio anubis) and pigs...
  4. Patel B, Larson S, Stern J. Electromyography of wrist and finger flexor muscles in olive baboons (Papio anubis). J Exp Biol. 2012;215:115-23 pubmed publisher
    ..EMG) patterns in both the wrist and finger flexor muscles in facultatively digitigrade olive baboons (Papio anubis) across a range of speeds...
  5. Meguerditchian A, Molesti S, Vauclair J. Right-handedness predominance in 162 baboons (Papio anubis) for gestural communication: consistency across time and groups. Behav Neurosci. 2011;125:653-60 pubmed publisher
    ..across time of the pattern of right-handedness for a species-specific communicative gesture in olive baboons (Papio anubis)...
  6. Schmitt V, Fischer J. Representational format determines numerical competence in monkeys. Nat Commun. 2011;2:257 pubmed publisher
    ..Reward replacement apparently facilitated representation of the food items as signifiers for other foods, which in turn supported a higher acuity in decision making...
  7. Dyl L, Topol M. The femoral artery and its branches in the baboon Papio anubis. Folia Morphol (Warsz). 2007;66:291-5 pubmed
    ..aim of the research was to examine the anatomy of the arterial system in the inguinal region, hip and thigh of Papio anubis. No description of this was found in the available scientific literature, although, at the same time, the ..
  8. Laidre M. Informative breath: olfactory cues sought during social foraging among Old World monkeys (Mandrillus sphinx, M. Leucophaeus, and Papio anubis). J Comp Psychol. 2009;123:34-44 pubmed publisher
    ..Each of three study species [mandrills (Mandrillus sphinx), drills (M. leucophaeus), and olive baboons (Papio anubis)] performed a prominent muzzle-muzzle behavior, potentially enabling individuals to smell others' mouths and ..
  9. Afshar Y, Hastings J, Roqueiro D, Jeong J, Giudice L, Fazleabas A. Changes in eutopic endometrial gene expression during the progression of experimental endometriosis in the baboon, Papio anubis. Biol Reprod. 2013;88:44 pubmed publisher
    ..Furthermore, this baboon model provides a powerful means whereby the early events associated with the pathology of disease and the resulting infertility may be elucidated...

More Information

Publications98

  1. Alexander M, Rothman R, Baumann M, Endres C, Brasic J, Wong D. Noradrenergic and dopaminergic effects of (+)-amphetamine-like stimulants in the baboon Papio anubis. Synapse. 2005;56:94-9 pubmed
    ..Viewed collectively, the present data indicate that typical clinical doses of phentermine and (+/-)-ephedrine may not release central DA in humans, a hypothesis that should ultimately be tested in controlled clinical studies...
  2. Luque R, Gahete M, Valentine R, Kineman R. Examination of the direct effects of metabolic factors on somatotrope function in a non-human primate model, Papio anubis. J Mol Endocrinol. 2006;37:25-38 pubmed publisher
    ..GHRH-receptor (GHRH-R) and ghrelin-receptor (GHS-R) mRNA levels, in primary pituitary cell cultures of baboons (Papio anubis) after 24 h treatment...
  3. Bergman T, Phillips Conroy J, Jolly C. Behavioral variation and reproductive success of male baboons (Papio anubis x Papio hamadryas) in a hybrid social group. Am J Primatol. 2008;70:136-47 pubmed
    We take advantage of an array of hybrid baboons (Papio anubis x Papio hamadryas) living in the same social group to explore the causes and consequences of different male mating strategies...
  4. Lee F, Lin Y, Deng M, Lee T, Huang C. Prevalence of antibody reaction with cercopithecine herpesvirus 1 antigen in Macaca cyclopis, Macaca fascicularis, and Papio anubis in Taiwan. J Med Primatol. 2007;36:343-7 pubmed
  5. D Souza S, Fazleabas A, Banerjee P, Sherwin J, Sharkey A, Farach Carson M, et al. Decidual heparanase activity is increased during pregnancy in the baboon (Papio anubis) and in in vitro decidualization of human stromal cells. Biol Reprod. 2008;78:316-23 pubmed
  6. Chai D, Cuneo S, Falconer H, Mwenda J, D Hooghe T. Olive baboon (Papio anubis anubis) as a model for intrauterine research. J Med Primatol. 2007;36:365-9 pubmed
  7. Lavelle D, Chin J, Vaitkus K, Redkar S, Phiasivongsa P, Tang C, et al. Oral decitabine reactivates expression of the methylated gamma-globin gene in Papio anubis. Am J Hematol. 2007;82:981-5 pubmed
    ..drugs at doses 17-34 times optimal subcutaneous doses of decitabine reactivates fetal hemoglobin, demethylates the epsilon- and gamma-globin gene promoters, and increases histone acetylation of these promoters in baboons (Papio anubis).
  8. Raabe B, Lovaglio J, Grover G, Brown S, Boucher J, Yuan Y, et al. Pharmacokinetics of cefovecin in cynomolgus macaques (Macaca fascicularis), olive baboons (Papio anubis), and rhesus macaques (Macaca mulatta). J Am Assoc Lab Anim Sci. 2011;50:389-95 pubmed
    ..properties of cefovecin were evaluated in cynomolgus macaques (Macaca fascicularis), olive baboons (Papio anubis), and rhesus macaques (Macaca mulatta) by using a single-dose (8 mg/kg SC) dosing regimen...
  9. Vauclair J, Meguerditchian A, Hopkins W. Hand preferences for unimanual and coordinated bimanual tasks in baboons (Papio anubis). Brain Res Cogn Brain Res. 2005;25:210-6 pubmed
    ..These are the first evidences of population-level handedness in baboons and the results are discussed in the context of evolutionary theories of cerebral dominance...
  10. Bezjian M, Gillespie T, Chapman C, Greiner E. Coprologic evidence of gastrointestinal helminths of forest baboons, Papio anubis, in Kibale National Park, Uganda. J Wildl Dis. 2008;44:878-87 pubmed
    ..From May to June 2004, we collected 41 fecal samples from free-ranging olive baboons (Papio anubis) within the forested Kibale National Park, Uganda...
  11. Mburu N, Obiero J, Waititu K, Mwaura B, Orawo J, Farah I, et al. Safety studies of a recently developed microbicidal contraceptive gel (UniPron) in female baboons (Papio anubis). Afr J Reprod Health. 2009;13:95-104 pubmed
    ..the vaginal epithelium, liver and kidney following UIniPron administration, ten healthy female olive baboons (Papio anubis) of reproductive age and of proven fertility were used...
  12. Hanna J, Polk J, Schmitt D. Forelimb and hindlimb forces in walking and galloping primates. Am J Phys Anthropol. 2006;130:529-35 pubmed
    ..Hum. Evol. 26:353-374) suggest that a relative reduction of forelimb vertical peak forces is part of an overall difference in locomotor mechanics between most primates and most nonprimate mammals during both walking and galloping...
  13. Kunz B, Linsenmair K. Seed size selection by olive baboons. Primates. 2008;49:239-45 pubmed publisher
    ..g. to decrease indigestible seed load or increase pulp intake per fruit. Olive baboons (Papio anubis, Cercopithecidae) are known to select seed size in unripe and mature pods of Parkia biglobosa (Mimosaceae) ..
  14. Tournier N, Goutal S, Auvity S, Traxl A, Mairinger S, Wanek T, et al. Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood-Brain Barrier: A PET Study on Nonhuman Primates. J Nucl Med. 2017;58:117-122 pubmed publisher
    ..b>Papio anubis baboons underwent PET scans of the brain after intravenous injection of 11C-erlotinib under baseline ..
  15. Saba W, Valette H, Schöllhorn Peyronneau M, Coulon C, Ottaviani M, Chalon S, et al. [11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET. Synapse. 2007;61:17-23 pubmed
  16. Nyachieo A, Spiessens C, Chai D, Mwenda J, D Hooghe T. Menstrual cycle synchronization, ovarian stimulation, and in vitro fertilization in olive baboons (Papio anubis): a prospective randomized study. Fertil Steril. 2009;91:602-10 pubmed publisher
    ..The baboon menstrual cycle can be synchronized using an oral contraceptive. A long GnRH agonist protocol for ovarian stimulation may be suitable for ovarian stimulation in baboons. ..
  17. Higham J, Warren Y, Adanu J, Umaru B, MacLarnon A, Sommer V, et al. Living on the edge: life-history of olive baboons at Gashaka-Gumti National Park, Nigeria. Am J Primatol. 2009;71:293-304 pubmed publisher
  18. Ram Y, Ross C. Evaluating the triplet hypothesis during rhythmic mastication in primates. J Exp Biol. 2018;221: pubmed publisher
    ..motor pattern in five different primate species, Eulemur fulvus, Propithecus verreauxi, Papio anubis, Macacafuscata and Pan troglodytes, using mean onset, peak and offset time relative to ..
  19. Lavelle D, Vaitkus K, Hankewych M, Singh M, DeSimone J. Developmental changes in DNA methylation and covalent histone modifications of chromatin associated with the epsilon-, gamma-, and beta-globin gene promoters in Papio anubis. Blood Cells Mol Dis. 2006;36:269-78 pubmed
    ..investigation addresses the role of DNA methylation and histone coding in globin gene switching in the baboon, Papio anubis. Bisulfite sequencing and chromatin immunoprecipitation studies were performed in erythroid cells purified from ..
  20. Donnez O, Soares M, Defrere S, Dehoux J, Van Langendonckt A, Donnez J, et al. Nerve fiber density in deep nodular endometriotic lesions induced in a baboon experimental model. Fertil Steril. 2013;100:1144-50 pubmed publisher
    ..Experimental animal study. Academic gynecology research unit. Ten baboons (Papio anubis). Recovery of induced endometriotic nodules and eutopic endometrium. Protein gene product (PGP) 9...
  21. Kil K, Ding Y, Lin K, Alexoff D, Kim S, Shea C, et al. Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec). Nucl Med Biol. 2007;34:153-63 pubmed
  22. ORELLANA R, García Solares J, Donnez J, Van Kerk O, Dolmans M, Donnez O. Important role of collective cell migration and nerve fiber density in the development of deep nodular endometriosis. Fertil Steril. 2017;107:987-995.e5 pubmed publisher
    ..Academic research unit. Three female baboons (Papio anubis). Recovery of induced deep nodular endometriotic nodules from baboons...
  23. Ducruet A, Mocco J, Mack W, Coon A, Marsh H, Pinsky D, et al. Pre-clinical evaluation of an sLe x-glycosylated complement inhibitory protein in a non-human primate model of reperfused stroke. J Med Primatol. 2007;36:375-80 pubmed
    ..A hypotensive response was also observed in animals treated with sCR1-sLe x. Conclusions Further work is necessary to explain the hypotensive response observed in primates prior to further clinical development of sCR1-sLe x. ..
  24. Byrne G, Stalboerger P, Davila E, Heppelmann C, Gazi M, McGregor H, et al. Proteomic identification of non-Gal antibody targets after pig-to-primate cardiac xenotransplantation. Xenotransplantation. 2008;15:268-76 pubmed publisher
    ..Further analysis of these antibody specificities using alternative methods is required to more fully define the repertoire of non-Gal antibody responses. ..
  25. Van Calsteren K, De Catte L, Devlieger R, Chai D, Amant F. Sonographic biometrical normograms and estimation of fetal weight in the baboon (Papio anubis). J Med Primatol. 2009;38:321-7 pubmed publisher
    ..23966 x AC(2) x FL + 1.623 x BPD(3). A high similarity between baboon and human growth charts is shown. The best equation for estimating the baboon fetal weight is proposed. ..
  26. Langoi D, Mwethera P, Abelson K, Farah I, Carlsson H. Reversal of ketamine/xylazine combination anesthesia by atipamezole in olive baboons (Papio anubis). J Med Primatol. 2009;38:404-10 pubmed publisher
    The potential of Atipamezole (ATI) to reverse Ketamine/Xylazine (KET/XYL) anesthesia in the Olive baboon (Papio anubis) was studied. Anesthesia was induced with 10 mg/kg KET and 0.5 mg/kg XYL intramuscularly...
  27. Awasthi S, Wolf R, White G. Ontogeny and phagocytic function of baboon lung dendritic cells. Immunol Cell Biol. 2009;87:419-27 pubmed publisher
    ..The fetal lung DCs were also less capable of phagocytosing E. coli as compared to the adult lung DCs (P<0.05). In conclusion, the fetal lung DCs are not only phenotypically immature, but also less efficient in phagocytosing E. coli. ..
  28. Kuwabara H, Gao Y, Stabin M, Coughlin J, Nimmagadda S, Dannals R, et al. Imaging α4β2 Nicotinic Acetylcholine Receptors (nAChRs) in Baboons with [18F]XTRA, a Radioligand with Improved Specific Binding in Extra-Thalamic Regions. Mol Imaging Biol. 2017;19:280-288 pubmed publisher
    ..The regional distribution of [18F]XTRA in the brain of Papio anubis baboons was evaluated in baseline and blocking experiments...
  29. Tung J, Charpentier M, Garfield D, Altmann J, Alberts S. Genetic evidence reveals temporal change in hybridization patterns in a wild baboon population. Mol Ecol. 2008;17:1998-2011 pubmed publisher
    ..We analysed patterns of hybridization between yellow baboons (Papio cynocephalus) and anubis baboons (Papio anubis) in a well-studied natural population in Amboseli National Park, Kenya, using genetic samples from 450 ..
  30. Galbany J, Martinez L, López Amor H, Espurz V, Hiraldo O, Romero A, et al. Error rates in buccal-dental microwear quantification using scanning electron microscopy. Scanning. 2005;27:23-9 pubmed
    ..The substitution of semiautomatic with fully automated procedures will completely avoid interobserver error rate differences. ..
  31. Cheng Q, Tucker E, Pine M, Sisler I, Matafonov A, Sun M, et al. A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo. Blood. 2010;116:3981-9 pubmed publisher
    ..Since fXII deficiency does not impair hemostasis, targeted inhibition of fXI activation by fXIIa may be a useful antithrombotic strategy associated with a low risk of bleeding complications. ..
  32. Reichard M, Thomas J, Chavez Suarez M, Cullin C, White G, Wydysh E, et al. Pilot Study to Assess the Efficacy of Ivermectin and Fenbendazole for Treating Captive-Born Olive Baboons (Papio anubis) Coinfected with Strongyloides fülleborni and Trichuris trichiura. J Am Assoc Lab Anim Sci. 2017;56:52-56 pubmed
    ..efficacy of combined treatment with ivermectin and fenbendazole (IVM-FBZ) for treating captive olive baboons (Papio anubis) infected with Strongyloides fülleborni and Trichuris trichiura, 2 common nematode parasites of these NHP...
  33. Hufnagel D, Goetz L, Hu Z, Nyachieo A, D Hooghe T, Fazleabas A, et al. Icon immunoconjugate treatment results in regression of red lesions in a non-human primate (Papio anubis) model of endometriosis. Reprod Biol. 2018;18:109-114 pubmed publisher
    ..This study evaluated Icon as a novel treatment for endometriosis in non-human primates (Papio anubis) using an adenoviral vector (AdIcon) delivery system...
  34. Gastinger M, Bordt A, Bernal M, Marshak D. Serotonergic retinopetal axons in the monkey retina. Curr Eye Res. 2005;30:1089-95 pubmed
    ..Receptors for serotonin are present in the primate retinas, and based on physiological studies in other mammals, these retinopetal axons are expected to modulate neuronal activity and regulate blood flow. ..
  35. Kobayashi T, Liu D, Ogawa H, Miwa Y, Nagasaka T, Maruyama S, et al. Removal of blood group A/B antigen in organs by ex vivo and in vivo administration of endo-beta-galactosidase (ABase) for ABO-incompatible transplantation. Transpl Immunol. 2009;20:132-8 pubmed publisher
    ..This alternative approach might be useful for minimizing antibody removal and anti-B cell immunosuppression as an adjuvant therapy in ABO-incompatible kidney, liver and possibly heart transplantation. ..
  36. Wanji S, Eyong E, Tendongfor N, Ngwa C, Esuka E, Kengne Ouafo A, et al. Parasitological, Hematological and Biochemical Characteristics of a Model of Hyper-microfilariaemic Loiasis (Loa loa) in the Baboon (Papio anubis). PLoS Negl Trop Dis. 2015;9:e0004202 pubmed publisher
    ..Fifteen baboons (Papio anubis) were infected with 600 infective larvae (L3) isolated from Chrysops vector flies...
  37. Lodge E, Ross C, Ortmann S, MacLarnon A. Influence of diet and stress on reproductive hormones in Nigerian olive baboons. Gen Comp Endocrinol. 2013;191:146-54 pubmed publisher
    ..the present study faecal progesterone and glucocorticoid levels were assessed in two troops of olive baboons (Papio anubis) in the same population...
  38. Lavelle D, Vaitkus K, Ling Y, Ruiz M, Mahfouz R, Ng K, et al. Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine. Blood. 2012;119:1240-7 pubmed publisher
    ..Combining oral THU with oral DAC changes DAC pharmacology in a manner that may facilitate accessible noncytotoxic DNMT1-targeted therapy. ..
  39. Lebovic D, Mwenda J, Chai D, Santi A, Xu X, D Hooghe T. Peroxisome proliferator-activated receptor-(gamma) receptor ligand partially prevents the development of endometrial explants in baboons: a prospective, randomized, placebo-controlled study. Endocrinology. 2010;151:1846-52 pubmed publisher
    ..Using this animal model, we have shown that thiazolidinedione is a promising drug for preventive treatment of endometriosis. ..
  40. Nyachieo A, Spiessens C, Chai D, Debrock S, Mwenda J, D Hooghe T. Randomized comparison of different ovarian stimulation regimens for assisted reproductive technology in baboons (Papio anubis). Fertil Steril. 2011;95:1354-9 pubmed publisher
    ..Fertilization by ICSI varied between 43% and 71%. In baboons, long and depot protocols yield similar numbers of MII oocytes; however, depot protocol may be preferable because only one injection of GnRH agonist is needed. ..
  41. Robb V, Pepe G, Albrecht E. Placental villous vascular endothelial growth factor expression and vascularization after estrogen suppression during the last two-thirds of baboon pregnancy. Endocrine. 2007;31:260-7 pubmed
  42. Daspre A, Heistermann M, Hodges J, Lee P, Rosetta L. Signals of female reproductive quality and fertility in colony-living baboons (Papio h. anubis) in relation to ensuring paternal investment. Am J Primatol. 2009;71:529-38 pubmed publisher
    ..Females with ovulatory but nonconceptive cycles were less attractive to males, especially during their maximal AGA swelling phase. ..
  43. Polk J, Psutka S, Demes B. Sampling frequencies and measurement error for linear and temporal gait parameters in primate locomotion. J Hum Evol. 2005;49:665-79 pubmed
    ..Finally, while slower camera speeds will always result in higher measurement errors than do faster camera speeds, this effect can be moderated to some extent by collecting sufficiently large samples of data. ..
  44. Garcia N, Ramis G, Pallares F, Seva J, Martinez C, Quereda J, et al. Clinical, histologic, and immunohistochemical features of an undifferentiated renal tubular carcinoma in a juvenile olive baboon (Papio anubis). J Vet Diagn Invest. 2009;21:535-9 pubmed
    An undifferentiated renal tubular carcinoma was diagnosed in a juvenile male olive baboon (Papio anubis). The animal suddenly appeared depressed and refused to eat...
  45. Dirks W, Humphrey L, Dean M, Jeffries T. The relationship of accentuated lines in enamel to weaning stress in juvenile baboons (Papio hamadryas anubis). Folia Primatol (Basel). 2010;81:207-23 pubmed publisher
    ..Because accentuated lines appear to indicate weaning stress at dietary transitions, weaning conflict may represent an honest signal of need on the part of the weanling. ..
  46. Isbell L, Bidner L, Crofoot M, Matsumoto Oda A, Farine D. GPS-identified, low-level nocturnal activity of vervets (Chlorocebus pygerythrus) and olive baboons (Papio anubis) in Laikipia, Kenya. Am J Phys Anthropol. 2017;164:203-211 pubmed publisher
    ..Here we examine the extent to which vervets (Chlorocebus pygerythrus) and olive baboons (Papio anubis) are active at night...
  47. Chowdhury D, Angov E, Kariuki T, Kumar N. A potent malaria transmission blocking vaccine based on codon harmonized full length Pfs48/45 expressed in Escherichia coli. PLoS ONE. 2009;4:e6352 pubmed publisher
    ..CH-rPfs48/45 formulated with Montanide ISA-51 when administered to nonhuman primates (Olive baboons, Papio anubis) resulted in uniformly high antibody responses (ELISA titers >2 million) in all five animals...
  48. Hylander W, Wall C, Vinyard C, Ross C, Ravosa M, Williams S, et al. Temporalis function in anthropoids and strepsirrhines: an EMG study. Am J Phys Anthropol. 2005;128:35-56 pubmed
  49. Bell J, Bergin I, Harris L, Chai D, Mullei I, Mwenda J, et al. The effects of a single cervical inoculation of Chlamydia trachomatis on the female reproductive tract of the baboon (Papio anubis). J Infect Dis. 2011;204:1305-12 pubmed publisher
    ..We sought to determine if the baboon could become infected with a single cervical inoculation of Chlamydia trachomatis...
  50. Tung J, Charpentier M, Mukherjee S, Altmann J, Alberts S. Genetic effects on mating success and partner choice in a social mammal. Am Nat. 2012;180:113-29 pubmed publisher
    ..cynocephalus) population that has experienced recent gene flow from a close sister taxon, the anubis baboon (Papio anubis), to examine how admixture-related genetic background affects mating behavior...
  51. Gilman G, Hansen W, Hagen M, Rosales A, Bailey K, McGregor C, et al. An echocardiographic left ventricular wall area index for functional detection of myocardial injury in hemodynamically unloaded hearts. Echocardiography. 2006;23:7-13 pubmed
    ..The biphasic morphometric response of LVWAI reflected changes in the cTnT levels and allowed echocardiographic detection of myocardial injury in hemodynamically unloaded hearts...
  52. Janowski K, Topol M. The topography of the superficial veins of the hind leg in the baboon Papio anubis in comparison with the superficial veins of the lower limb in humans. Folia Morphol (Warsz). 2005;64:287-91 pubmed
    Our studies were carried out on 8 male and 2 female baboons Papio anubis cadavers. We examined a total of 20 hind legs. The vessels of the hind leg were filled with coloured latex...
  53. Nyachieo A, Spiessens C, Chai D, Kiulia N, Willemen D, Mwenda J, et al. Ovarian tissue cryopreservation by vitrification in olive baboons (papio anubis): a pilot study. Gynecol Obstet Invest. 2013;75:157-62 pubmed publisher
    ..However, this technique has not been optimized. The aim of this study was to evaluate the baboon as a model for the preclinical study of ovarian tissue cryopreservation by vitrification and thawing...
  54. Goodwin A, Gibson K, Weerts E. Physical dependence on gamma-hydroxybutrate (GHB) prodrug 1,4-butanediol (1,4-BD): time course and severity of withdrawal in baboons. Drug Alcohol Depend. 2013;132:427-33 pubmed publisher
    ..Although there are case reports of a withdrawal syndrome following 1,4-BD use, no studies have evaluated the physical dependence potential of 1,4-BD and characterized the time course of withdrawal...
  55. Giffard C, Young A, Mézenge F, Derlon J, Baron J. Histopathological effects of delayed reperfusion after middle cerebral artery occlusion in the anesthetized baboon. Brain Res Bull. 2005;67:335-40 pubmed
    ..Cautiously extrapolating to the human situation, our findings suggest that even late mechanical recanalization may not promote brain damage and could be considered in selected cases...
  56. Colby G, Coon A, Connolly E, Ambron R. Activation of c-Jun and ATF-2 in primate motor cranial nerve nuclei is not associated with apoptosis following axotomy. Exp Neurol. 2005;194:57-65 pubmed
    ..This report serves as a basic inquiry into the neuronal response to cranial nerve injury in primates...
  57. Ridler K, Plisson C, Rabiner E, Gunn R, Easwaramoorthy B, Abi Dargham A, et al. Characterization of in vivo pharmacological properties and sensitivity to endogenous serotonin of [11C] P943: a positron emission tomography study in Papio anubis. Synapse. 2011;65:1119-27 pubmed publisher
    ..11 C] P943 shows promise as a tracer to image serotonin function in healthy subjects as well as subjects with psychiatric or neurologic conditions...
  58. Chin J, Singh M, Banzon V, Vaitkus K, Ibanez V, Kouznetsova T, et al. Transcriptional activation of the gamma-globin gene in baboons treated with decitabine and in cultured erythroid progenitor cells involves different mechanisms. Exp Hematol. 2009;37:1131-42 pubmed publisher
    ..To investigate the mechanism(s) responsible for increased gamma-globin expression in vivo in decitabine-treated baboons and in vitro in cultured erythroid progenitor cells (EPC) from adult baboon bone marrow (BM)...
  59. Lavoie P, Metellus P, Velly L, Vidal V, Rolland P, Mekaouche M, et al. Functional cerebral venous outflow in swine and baboon: feasibility of an intracranial venous hypertension model. J Invest Surg. 2008;21:323-9 pubmed publisher
    ..To evaluate the feasibility of performing a functional cerebral venous outflow blockage in two large animals species, the swine and the baboon, for elaboration of venous hypertension models...
  60. Chen M, Kuwabara H, Zhou Y, Adams R, Brasic J, McGlothan J, et al. VMAT2 and dopamine neuron loss in a primate model of Parkinson's disease. J Neurochem. 2008;105:78-90 pubmed
    ..Genetic or environmental factors that decrease VMAT2 function may be important determinants of PD...
  61. Rosetta L, Lee P, Garcia C. Energetics during reproduction: a doubly labeled water study of lactating baboons. Am J Phys Anthropol. 2011;144:661-8 pubmed publisher
  62. Allison S, Halliday L, French J, Novikov D, Fortman J. Assessment of buprenorphine, carprofen, and their combination for postoperative analgesia in olive baboons (Papio anubis). J Am Assoc Lab Anim Sci. 2007;46:24-31 pubmed
    ..In this study, the use of carprofen or a combination of carprofen plus buprenorphine provided more reliable postoperative analgesia than buprenorphine alone...
  63. Ezzelarab M, Yeh P, Wagner R, Cooper D. Babesia as a complication of immunosuppression following pig-to-baboon heart transplantation. Xenotransplantation. 2007;14:162-5 pubmed
    ..Immunosuppression can reduce the host's immune system, and result in proliferation of the parasite, leading to hemolysis and other features of infection, sometimes with fatal outcome...
  64. Bell J, Bergin I, Natavio M, Jibrel F, Zochowski M, Weadock W, et al. Feasibility of LNG-IUS in a baboon model. Contraception. 2013;87:380-4 pubmed publisher
    ..This study sought to determine whether human-use IUDs could be seated correctly in the uterus of the baboon...
  65. Ramis G, Martínez Alarcón L, Majado M, Quereda J, Mendonca L, Herrero Medrano J, et al. Assessment of in vitro heparin complement regulation capacity during real-time cell analyzer antibody-mediated cytolysis assay: compatibility studies for pig-to-baboon xenotransplantation. Transplant Proc. 2012;44:1584-8 pubmed publisher
  66. Gasser R, de Gruijter J, Polderman A. Insights into the epidemiology and genetic make-up of Oesophagostomum bifurcum from human and non-human primates using molecular tools. Parasitology. 2006;132:453-60 pubmed
    ..Recent research findings are discussed mainly in relation to non-human primates being reservoirs of infection, and the consequences for the prevention and control of oesophagostomiasis in humans are briefly discussed...
  67. Milak M, Severance A, Prabhakaran J, Kumar J, Majo V, Ogden R, et al. In vivo serotonin-sensitive binding of [11C]CUMI-101: a serotonin 1A receptor agonist positron emission tomography radiotracer. J Cereb Blood Flow Metab. 2011;31:243-9 pubmed publisher
    ..Two Papio anubis were scanned, using [(11)C]CUMI-101 intravenous bolus of 4.5 ± 1.5 mCi...
  68. Seress L, Frotscher M. Morphological variability is a characteristic feature of granule cells in the primate fascia dentata: a combined Golgi/electron microscope study. J Comp Neurol. 1990;293:253-67 pubmed
    ..The hippocampi of three adult rhesus monkeys (Macaca mulatta) and two 1-year-old female baboons (Papio anubis) were used for a combined Golgi/electron microscope (EM) study...
  69. Cosgrove K, Kloczynski T, Nabulsi N, Weinzimmer D, Lin S, Staley J, et al. Assessing the sensitivity of [¹¹C]p943, a novel 5-HT1B radioligand, to endogenous serotonin release. Synapse. 2011;65:1113-7 pubmed publisher
    ..Receptor occupancy by P943 (0.2 mg/kg) was 68 and 86% in the baboons. PET imaging of 5-HT(1B) receptors with [¹¹C]P943 may be a useful approach for measuring changes in endogenous 5-HT in the living human brain...
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    ..Our purpose was to examine the cerebral metabolic response to stroke in baboons with MR spectroscopy and to correlate metabolite levels with functional neurologic outcomes...
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    ..2.1]heptane, exhibited good properties as a first practical PET radioligand for imaging of extrathalamic nAChR in baboon brain and holds promise for further investigation for human studies...
  73. Mugnaini M, Iavarone L, Cavallini P, Griffante C, Oliosi B, Savoia C, et al. Occupancy of brain dopamine D3 receptors and drug craving: a translational approach. Neuropsychopharmacology. 2013;38:302-12 pubmed publisher
    ..In addition, they provide the first clinical evidence of potential efficacy of a selective D(3)R antagonist for the treatment of substance-use disorders...
  74. Baldwin R, Zoghbi S, Staley J, Brenner E, Al Tikriti M, Amici L, et al. Chemical fate of the nicotinic acetylcholinergic radiotracer [123I]5-IA-85380 in baboon brain and plasma. Nucl Med Biol. 2006;33:549-54 pubmed
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    ..When similar dose response curves are obtained in at least two animal models, the extrapolation to expected therapeutic effects in humans might be considered more reliable...
  76. Tournier N, Saba W, Cisternino S, Peyronneau M, Damont A, Goutal S, et al. Effects of selected OATP and/or ABC transporter inhibitors on the brain and whole-body distribution of glyburide. AAPS J. 2013;15:1082-90 pubmed publisher
    ..Conversely, P-gp, BCRP, and probably multidrug resistance protein 4 work in synergy to limit GLB brain uptake. ..
  77. Hooker J, Munro T, Beguin C, Alexoff D, Shea C, Xu Y, et al. Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residence. Neuropharmacology. 2009;57:386-91 pubmed publisher
    ..Our results suggest that protecting salvinorin A derivatives from metabolism will prolong duration of action, but only when administered by routes giving slow absorption...
  78. Trong P, Rieke F. Origin of correlated activity between parasol retinal ganglion cells. Nat Neurosci. 2008;11:1343-51 pubmed publisher
    ..These results provide a mechanistic picture of how correlated activity is produced in a population of neurons that are critical for visual perception...
  79. Nyachieo A, Spiessens C, Chai D, Kiulia N, Mwenda J, D Hooghe T. Baboon spermatology: basic assessment and reproducibility in olive baboons (Papio anubis). J Med Primatol. 2012;41:297-303 pubmed publisher
    ..The objective of this study was to document basic spermatology values and investigate the reproducibility of these variables in the same baboons 1 or 3 months later in a larger number of baboons...
  80. Hukkanen R, Liggitt H, Murnane R, Frevert C. Systemic inflammatory response syndrome in nonhuman primates culminating in multiple organ failure, acute lung injury, and disseminated intravascular coagulation. Toxicol Pathol. 2009;37:799-804 pubmed publisher
    ..Experimental manipulation of NHP models may be complicated by SIRS and accompanying rapid clinical decompensation. Such adverse events may compromise toxicological studies and should be avoided when possible...
  81. Slifstein M, Suckow R, Javitch J, Cooper T, Lieberman J, Abi Dargham A. Characterization of in vivo pharmacokinetic properties of the dopamine D1 receptor agonist DAR-0100A in nonhuman primates using PET with [11C] NNC112 and [11C] raclopride. J Cereb Blood Flow Metab. 2011;31:293-304 pubmed publisher
    ..This is the first demonstration with PET of a significant occupancy by a full D1 agonist in vivo...
  82. Riss P, Hooker J, Shea C, Xu Y, Carter P, Warner D, et al. Characterisation of [¹¹C]PR04.MZ in Papio anubis baboon: a selective high-affinity radioligand for quantitative imaging of the dopamine transporter. Bioorg Med Chem Lett. 2012;22:679-82 pubmed publisher
    ..MZ ([(11)C]-1) has been developed using GMP compliant equipment. An adult female Papio anubis baboon was studied using a test-retest protocol with [(11)C]-1 in order to assess test-retest reliability, ..
  83. Nobrega Lee M, Hubbard G, Loverde P, Carvalho Queiroz C, Conn D, Rohde K, et al. Sparganosis in wild-caught baboons (Papio cynocephalus anubis). J Med Primatol. 2007;36:47-54 pubmed
    ..Sparganosis is the infection of a paratenic host with the plerocercoid metacestode of Spirometra spp. A 12-year-old captive, pregnant, wild-caught baboon from Tanzania had multiple subcutaneous nodules...
  84. Goodwin A, Griffiths R, Brown P, Froestl W, Jakobs C, Gibson K, et al. Chronic intragastric administration of gamma-butyrolactone produces physical dependence in baboons. Psychopharmacology (Berl). 2006;189:71-82 pubmed
    ..Abuse of gamma-hydroxybutyrate (GHB) and its precursors is a public health concern. Gamma-butyrolactone (GBL) is found in commercially available products and, when ingested, is metabolized to GHB...
  85. Mocco J, Mack W, Ducruet A, King R, Sughrue M, Coon A, et al. Preclinical evaluation of the neuroprotective effect of soluble complement receptor type 1 in a nonhuman primate model of reperfused stroke. J Neurosurg. 2006;105:595-601 pubmed
  86. Higham J, MacLarnon A, Heistermann M, Ross C, Semple S. Rates of self-directed behaviour and faecal glucocorticoid levels are not correlated in female wild olive baboons (Papio hamadryas anubis). Stress. 2009;12:526-32 pubmed publisher
    ..We discuss several possible interpretations of our results, including the possibility that SDBs represent a behavioural coping mechanism, helping to ameliorate the physiological stress response...
  87. Moser A, Hey J, Dranchak P, Karaman M, Zhao J, Cox L, et al. Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells. Lipids Health Dis. 2013;12:10 pubmed publisher
    ..In contrast, humans cannot derive PA from chlorophyll and instead normally obtain it only from meat, dairy, and fish products...
  88. Park W, Kothapalli K, Lawrence P, Tyburczy C, Brenna J. An alternate pathway to long-chain polyunsaturates: the FADS2 gene product Delta8-desaturates 20:2n-6 and 20:3n-3. J Lipid Res. 2009;50:1195-202 pubmed publisher
    ..These findings provide unequivocal molecular evidence for a novel alternative biosynthetic route to long-chain polyunsaturated fatty acids in mammals from substrates previously considered to be dead-end products...
  89. de Gruijter J, Gasser R, Polderman A, Asigri V, Dijkshoorn L. High resolution DNA fingerprinting by AFLP to study the genetic variation among Oesophagostomum bifurcum (Nematoda) from human and non-human primates from Ghana. Parasitology. 2005;130:229-37 pubmed
    ..The results demonstrated the effectiveness of the present AFLP method for establishing genetic variation within O. bifurcum, and indicates its applicability to other parasitic nematodes of human and/or veterinary health importance...