domestic sheep


Summary: A species of sheep, Ovis aries, descended from Near Eastern wild forms, especially mouflon.

Top Publications

  1. Ligios C, Sigurdson C, Santucciu C, Carcassola G, Manco G, Basagni M, et al. PrPSc in mammary glands of sheep affected by scrapie and mastitis. Nat Med. 2005;11:1137-8 pubmed
  2. Kelley S, Cassirer E, Weiser G, Safaee S. Phylogenetic diversity of Pasteurellaceae and horizontal gene transfer of leukotoxin in wild and domestic sheep. Infect Genet Evol. 2007;7:13-23 pubmed
    ..and cross-transmission rates of Pasteurellaceae bacteria in populations of bighorn sheep, Dall's sheep, domestic sheep and domestic goats...
  3. Hecht J, Kuhl H, Haas S, Bauer S, Poustka A, Lienau J, et al. Gene identification and analysis of transcripts differentially regulated in fracture healing by EST sequencing in the domestic sheep. BMC Genomics. 2006;7:172 pubmed publisher
  4. Beraldi D, McRae A, Gratten J, Slate J, Visscher P, Pemberton J. Development of a linkage map and mapping of phenotypic polymorphisms in a free-living population of Soay sheep (Ovis aries). Genetics. 2006;173:1521-37 pubmed
    ..Horn type maps to chromosome 10, a location similar to that previously identified in domestic sheep. These findings represent an advance in the dissection of the genetic diversity in the wild and provide the ..
  5. Maybauer D, Maybauer M, Traber L, Westphal M, Nakano Y, Enkhbaatar P, et al. Effects of severe smoke inhalation injury and septic shock on global hemodynamics and microvascular blood flow in sheep. Shock. 2006;26:489-95 pubmed
    ..aeruginosa infusion. The results of this study reflect the complex pathophysiological variances of the combined injury and may provide a basis for future investigations for the treatment of this kind of injury...
  6. Beraldi D, McRae A, Gratten J, Pilkington J, Slate J, Visscher P, et al. Quantitative trait loci (QTL) mapping of resistance to strongyles and coccidia in the free-living Soay sheep (Ovis aries). Int J Parasitol. 2007;37:121-9 pubmed
    ..the genetic parameters of the study traits were also estimated and compared with previous studies in Soay and domestic sheep. Strongyle FEC and coccidia FOC showed moderate heritability (h(2)=0.26 and 0...
  7. Meadows J, Cemal I, Karaca O, Gootwine E, Kijas J. Five ovine mitochondrial lineages identified from sheep breeds of the near East. Genetics. 2007;175:1371-9 pubmed
  8. Gratten J, Beraldi D, Lowder B, McRae A, Visscher P, Pemberton J, et al. Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep. Proc Biol Sci. 2007;274:619-26 pubmed publisher
    ..0001, LOD=110.20), and very tight linkage between Coat colour and TYRP1 (LOD=29.50)...
  9. Peter C, Bruford M, Perez T, Dalamitra S, Hewitt G, Erhardt G. Genetic diversity and subdivision of 57 European and Middle-Eastern sheep breeds. Anim Genet. 2007;38:37-44 pubmed
    ..Within the last group, two less-distinct clusters comprised the Merino-type and Alpine breeds respectively. The incomplete demarcations of most clusters probably reflects cross-breeding and/or upgrading...

More Information

Publications146 found, 100 shown here

  1. Ushizawa K, Takahashi T, Hosoe M, Ohkoshi K, Hashizume K. Expression and characterization of novel ovine orthologs of bovine placental prolactin-related proteins. BMC Mol Biol. 2007;8:95 pubmed
    ..We investigated placental PRP in sheep in order to gain a comprehensive understanding of the function and evolution of these molecules. We also examined the sequence properties, expression and lactogenic activation of the cloned genes...
  2. Hadjipavlou G, Matika O, Clop A, Bishop S. Two single nucleotide polymorphisms in the myostatin (GDF8) gene have significant association with muscle depth of commercial Charollais sheep. Anim Genet. 2008;39:346-53 pubmed publisher
    ..6723A allele frequency of 0.7. Our findings indicate that marker-assisted selection using these two GDF8 SNPs would be beneficial for the Charollais breed...
  3. Boman I, Klemetsdal G, Blichfeldt T, Nafstad O, Vage D. A frameshift mutation in the coding region of the myostatin gene (MSTN) affects carcass conformation and fatness in Norwegian White Sheep (Ovis aries). Anim Genet. 2009;40:418-22 pubmed publisher
    ..In our material, these MSTN mutations segregated in a pattern showing that they reside in two different haplotypes. The phenotypic effect of the single base deletion is more profound than that of the 3'-UTR mutation...
  4. Chen S, Duan Z, Sha T, Xiangyu J, Wu S, Zhang Y. Origin, genetic diversity, and population structure of Chinese domestic sheep. Gene. 2006;376:216-23 pubmed
    To characterize the origin, genetic diversity, and phylogeographic structure of Chinese domestic sheep, we here analyzed a 531-bp fragment of mtDNA control region of 449 Chinese autochthonous sheep from 19 breeds/populations from 13 ..
  5. Crawford A, Paterson K, Dodds K, Diez Tascon C, Williamson P, Roberts Thomson M, et al. Discovery of quantitative trait loci for resistance to parasitic nematode infection in sheep: I. Analysis of outcross pedigrees. BMC Genomics. 2006;7:178 pubmed
    ..This study was undertaken to identify regions of the genome, quantitative trait loci (QTL) that contain genes affecting resistance to parasitic nematodes...
  6. Meadows J, Hanotte O, Drogemuller C, Calvo J, Godfrey R, Coltman D, et al. Globally dispersed Y chromosomal haplotypes in wild and domestic sheep. Anim Genet. 2006;37:444-53 pubmed
    ..A-oY1 also had the highest frequency (71.4%) within 458 domestic sheep drawn from 65 breeds sampled from Africa, Asia, Australia, the Caribbean, Europe, the Middle East and Central ..
  7. Dalrymple B, Kirkness E, Nefedov M, McWilliam S, Ratnakumar A, Barris W, et al. Using comparative genomics to reorder the human genome sequence into a virtual sheep genome. Genome Biol. 2007;8:R152 pubmed
    ..Is it possible to construct an accurate and detailed subgene-level map of a genome using bacterial artificial chromosome (BAC) end sequences, a sparse marker map, and the sequences of other genomes?..
  8. Lawson Handley L, Byrne K, Santucci F, Townsend S, Taylor M, Bruford M, et al. Genetic structure of European sheep breeds. Heredity (Edinb). 2007;99:620-31 pubmed
    ..Finally, using a Bayesian cluster analysis, we uncovered evidence of admixture between breeds, which has important implications for breed management...
  9. Marcos Carcavilla A, Calvo J, Gonz lez C, Serrano C, Moazami Goudarzi K, Laurent P, et al. Structural and functional analysis of the ovine laminin receptor gene (RPSA): Possible involvement of the LRP/LR protein in scrapie response. Mamm Genome. 2008;19:92-105 pubmed publisher
  10. Herrmann Hoesing L, White S, Kappmeyer L, Herndon D, Knowles D. Genomic analysis of Ovis aries (Ovar) MHC class IIa loci. Immunogenetics. 2008;60:167-76 pubmed publisher
    ..This is the first ruminant finished sequence of the DQB2-DRB1 region, and this sequence information will aid in whole genome and transcriptome analyses of MHC class II...
  11. Kijas J, Townley D, Dalrymple B, Heaton M, Maddox J, McGrath A, et al. A genome wide survey of SNP variation reveals the genetic structure of sheep breeds. PLoS ONE. 2009;4:e4668 pubmed publisher
    ..Furthermore, the identification of a subset of SNP able to assign individuals into broad groupings demonstrates even a small panel of markers may be suitable for applications such as traceability...
  12. Raadsma H, Thomson P, Zenger K, Cavanagh C, Lam M, Jonas E, et al. Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight. Genet Sel Evol. 2009;41:34 pubmed publisher
    ..Fifty-four putative QTL were identified on nine chromosomes. Significant QTL with sex-specific effects (i.e. QTL x sex interaction) in the range of 0.4 to 0.7 SD were found on ovine chromosomes 1, 3, 6, 11, 21, 23, 24 and 26...
  13. Tapio M, Ozerov M, Tapio I, Toro M, Marzanov N, Cinkulov M, et al. Microsatellite-based genetic diversity and population structure of domestic sheep in northern Eurasia. BMC Genet. 2010;11:76 pubmed publisher
    ..In addition we estimated how important within-species diversity hotspots are in livestock conservation...
  14. Meadows J, Chan E, Kijas J. Linkage disequilibrium compared between five populations of domestic sheep. BMC Genet. 2008;9:61 pubmed publisher
    ..Four economically important Australian sheep flocks, three pure breeds (White Faced Suffolk, Poll Dorset, Merino) and a crossbred population (Merino x Border Leicester), along with an inbred Australian Merino museum flock were analysed...
  15. Konnai S, Takeshima S, Tajima S, Yin S, Okada K, Onuma M, et al. The influence of ovine MHC class II DRB1 alleles on immune response in bovine leukemia virus infection. Microbiol Immunol. 2003;47:223-32 pubmed
    ..To determine the proliferating cells, we tried a blocking assay with monoclonal antibodies such as anti-CD4, -CD8 and -DR molecule. We found that these proliferating cells were MHC-restricted CD4+ T-cells...
  16. Houston F, Goldmann W, Chong A, Jeffrey M, Gonzalez L, Foster J, et al. Prion diseases: BSE in sheep bred for resistance to infection. Nature. 2003;423:498 pubmed
  17. Cox R, Burke A, Soejima K, Murakami K, Katahira J, Traber L, et al. Airway obstruction in sheep with burn and smoke inhalation injuries. Am J Respir Cell Mol Biol. 2003;29:295-302 pubmed
  18. Benestad S, Sarradin P, Thu B, Schönheit J, Tranulis M, Bratberg B. Cases of scrapie with unusual features in Norway and designation of a new type, Nor98. Vet Rec. 2003;153:202-8 pubmed
    ..From a diagnostic point of view, these features indicate that this type of scrapie, designated Nor98, could have been overlooked and may be of significance for sampling in scrapie surveillance programmes...
  19. Mena A, Nichani A, Popowych Y, Godson D, Dent D, Townsend H, et al. Innate immune responses induced by CpG oligodeoxyribonucleotide stimulation of ovine blood mononuclear cells. Immunology. 2003;110:250-7 pubmed
    ..These observations support the conclusion that differences in CpG-ODN-induced responses exist among species and that specific ODN sequences can significantly influence innate immune responses...
  20. Cockett N. Current status of the ovine genome map. Cytogenet Genome Res. 2003;102:76-8 pubmed
    ..In order to improve the efficiency of these investigations, it is imperative that efforts on the sheep comparative map be continued...
  21. Tapio I, Tapio M, Grislis Z, Holm L, Jeppsson S, Kantanen J, et al. Unfolding of population structure in Baltic sheep breeds using microsatellite analysis. Heredity (Edinb). 2005;94:448-56 pubmed
    ..Combining these genetic populations with phenotypic and aetiological data will enable formulation of the most informed recommendations for gene resource management...
  22. Ross M, Desai M, Guerra C, Wang S. Programmed syndrome of hypernatremic hypertension in ovine twin lambs. Am J Obstet Gynecol. 2005;192:1196-204 pubmed
    ..Because the sheep pregnancy consists of singleton and twin litters, we sought to determine the impact of ovine twin gestation and twin nursing on the cardiovascular and renal function of the offspring...
  23. Herrera E, Ebensperger G, Krause B, Riquelme R, Reyes R, Capetillo M, et al. Sildenafil reverses hypoxic pulmonary hypertension in highland and lowland newborn sheep. Pediatr Res. 2008;63:169-75 pubmed
    ..The distal pulmonary arteries showed an increased wall thickness in HLNB. Our results showed that HLNB are more sensitive to sildenafil and therefore could be useful for treatment of pulmonary hypertension in high-altitude neonates. ..
  24. Guan F, Yang L, An J, Liu S, Shi G. [Development of a rapid mismatch PCR method using tetra-primer ARMS for detection of BMPR-IB gene mutation in sheep]. Yi Chuan. 2005;27:579-83 pubmed
    ..The detection efficiency of sheep BMPR-IB genotyping was greatly improved by use of this method. ..
  25. Tchirikov M, Strohner M, Popovic S, Hecher K, Schröder H. Cardiac output following fetoscopic coagulation of major placental vessels in fetal sheep. Ultrasound Obstet Gynecol. 2008;32:917-22 pubmed publisher
    ..The combined CO was not significantly affected by the vascular obstruction, whereas the fraction of combined CO directed to the placenta was reduced. ..
  26. Frasch M, Muller T, Weiss C, Schwab K, Schubert H, Schwab M. Heart rate variability analysis allows early asphyxia detection in ovine fetus. Reprod Sci. 2009;16:509-17 pubmed publisher
    ..05). Our results suggest that an increase of RMSSD in association with FHR decelerations reflects initial vagal activation during fetal asphyxia. RMSSD may accurately identify asphyxic fetuses early. Clinical validation is needed. ..
  27. Hoberg E, Kumsa B, Pilitt P, Abrams A. Synlophe structure in Pseudomarshallagia elongata (Nematoda: Trichostrongyloidea), abomasal parasites among Ethiopian ungulates, with consideration of other morphological attributes and differentiation within the Ostertagiinae. J Parasitol. 2010;96:401-11 pubmed publisher
    ..Although this is particularly important in regions that remain poorly known, such as Africa, the principle certainly applies more broadly...
  28. Alberti A, Pirino S, Pintore F, Addis M, Chessa B, Cacciotto C, et al. Ovis aries Papillomavirus 3: a prototype of a novel genus in the family Papillomaviridae associated with ovine squamous cell carcinoma. Virology. 2010;407:352-9 pubmed publisher
    ..Taken together, the co-occurrence of OaPV3 and tumors, its cell and tissue tropism, and its gene repertoire, suggests a role for this virus in development of sheep squamous cell carcinoma...
  29. Nandi S, Tripathi S, Gupta P, Mondal S. Nutritional and metabolic stressors on ovine oocyte development and granulosa cell functions in vitro. Cell Stress Chaperones. 2018;23:357-371 pubmed publisher
    ..These results suggested that the decreased function of GCs may cause ovarian dysfunction and offered an improved understanding of the molecular mechanism responsible for the low fertility in metabolic stressed condition. ..
  30. Andreasen J, Munksgaard E, Bakland L. Comparison of fracture resistance in root canals of immature sheep teeth after filling with calcium hydroxide or MTA. Dent Traumatol. 2006;22:154-6 pubmed
    ..This finding may be of importance in the decision of treatment plans for teeth with pulp necrosis and immature root formation. ..
  31. Zabłocka A, Janusz M, Macała J, Lisowski J. A proline-rich polypeptide complex (PRP) isolated from ovine colostrum. Modulation of H2O2 and cytokine induction in human leukocytes. Int Immunopharmacol. 2007;7:981-8 pubmed
    ..The regulatory effect of the PRP on the innate immunity may shed some light on understanding the beneficial effects of this polypeptide complex in AD patients. ..
  32. McClure S. Mucosal delivery of native and recombinant protein vaccines against Trichostrongylus colubriformis. Int J Parasitol. 2009;39:599-606 pubmed publisher
    ..They warrant the further investigation of appropriate mucosal delivery methods and adjuvants for induction of protective mucosal responses to stages and species of gastrointestinal helminths which do not ingest serum antibodies. ..
  33. Di Domenico M, Di Giuseppe M, Wicochea Rodríguez J, Camma C. Validation of a fast real-time PCR method to detect fraud and mislabeling in milk and dairy products. J Dairy Sci. 2017;100:106-112 pubmed publisher
    ..The 4 TaqMan assays were confirmed to be a useful tool for milk and dairy product authentication. ..
  34. Petersen H, Al Sabi M, Larsen G, Jensen T, Chriel M. First report of Taenia ovis infection in Danish sheep (Ovis aries). Vet Parasitol. 2018;251:3-6 pubmed publisher
    ..However, infected meat is usually condemned due to aesthetic reasons causing economic losses. Thus, finding of T. ovis is of concern to sheep meat producers in the area, as the infection could have spread further on to other farms. ..
  35. Kasaian M, Donaldson D, Tchistiakova L, Marquette K, Tan X, Ahmed A, et al. Efficacy of IL-13 neutralization in a sheep model of experimental asthma. Am J Respir Cell Mol Biol. 2007;36:368-76 pubmed publisher
    ..These findings suggest that IL-13 contributes to allergen-induced airway responses in this sheep model of asthma, and that neutralization of IL-13 is an effective strategy for blocking these A. suum-induced effects...
  36. Roselli C, Estill C, Stadelman H, Stormshak F. The volume of the ovine sexually dimorphic nucleus of the preoptic area is independent of adult testosterone concentrations. Brain Res. 2009;1249:113-7 pubmed publisher
    ..These results suggest that differences in the size of the oSDN in adult sheep were not influenced by adult exposure to testosterone. ..
  37. Liu N, Liu Z, Hu P, Zhang Y, Lu S, Li Y, et al. Full-Length cDNA Cloning, Molecular Characterization and Differential Expression Analysis of Lysophospholipase I from Ovis aries. Int J Mol Sci. 2016;17: pubmed publisher
    ..The results suggest that OaLypla1 may have an important physiological role in the host response to bacteria. The function of OaLypla1 in the host response to bacterial infection requires further study in the future. ..
  38. Belloy L, Giacometti M, Boujon P, Waldvogel A. Detection of Dichelobacter nodosus in wild ungulates (Capra ibex ibex and Ovis aries musimon) and domestic sheep suffering from foot rot using a two-step polymerase chain reaction. J Wildl Dis. 2007;43:82-8 pubmed
    ..Using this assay, we were able to diagnose D. nodosus infections of ibex, mouflon, and domestic sheep in natural outbreaks. From these results we conclude that D...
  39. Byun S, Fang Q, Zhou H, Hickford J. Rapid genotyping of the ovine ADRB3 gene by polymerase chain reaction-single-strand conformation polymorphism (PCR-SSCP). Mol Cell Probes. 2008;22:69-70 pubmed
  40. Hayashi K, O Connell A, Juengel J, McNatty K, Davis G, Bazer F, et al. Postnatal uterine development in Inverdale ewe lambs. Reproduction. 2008;135:357-65 pubmed publisher
  41. Pfaff F, Schlottau K, Scholes S, Courtenay A, Hoffmann B, Höper D, et al. A novel astrovirus associated with encephalitis and ganglionitis in domestic sheep. Transbound Emerg Dis. 2017;64:677-682 pubmed publisher
    ..In conclusion, these are the first reported cases of astrovirus infection in domestic sheep that were associated with encephalitis and ganglionitis.
  42. Behrend M, Kluge E. The fate of homograft tracheal transplants in sheep. World J Surg. 2008;32:1669-75 pubmed publisher
    ..They are replaced by scar/granulation tissue that cannot secure the stability of the trachea. Therefore, further experiments with respect to the biocompatability of homografts appear to be necessary. ..
  43. Meurisse M, Chaillou E, Levy F. Afferent and efferent connections of the cortical and medial nuclei of the amygdala in sheep. J Chem Neuroanat. 2009;37:87-97 pubmed publisher
    ..These data are discussed in relation with olfactory learning in the context of sexual and maternal behavior in sheep. ..
  44. Paknejad M, Emtiaz S, Rokn A, Islamy B, Safiri A. Histologic and histomorphometric evaluation of two bone substitute materials for bone regeneration: an experimental study in sheep. Implant Dent. 2008;17:471-9 pubmed publisher
    ..The main objective of the present study is the evaluation of quality, density, and thickness of the newly formed bone in experimental defects treated with deproteinized bovine bone mineral (DBBM) and bioapatite-collagen...
  45. Morandi F, Benazzi C, Simoni P. Adenocarcinoma of apocrine sweat glands in a mouflon (Ovis musimon). J Vet Diagn Invest. 2005;17:389-92 pubmed
    ..On the basis of histological and ultrastructural findings, this tumor was diagnosed as a tubulopapillary adenocarcinoma, arising from apocrine sweat glands of the skin. ..
  46. Houdijk J, Jackson F, Coop R, Kyriazakis I. Rapid improvement of immunity to Teladorsagia circumcincta is achieved through a reduction in the demand for protein in lactating ewes. Int J Parasitol. 2006;36:219-27 pubmed
    ..circumcincta. This may be associated with increased parasite expulsion, reduced fecundity and non-parasite specific reduction of in vitro larval establishment...
  47. Limesand S, Rozance P, Smith D, Hay W. Increased insulin sensitivity and maintenance of glucose utilization rates in fetal sheep with placental insufficiency and intrauterine growth restriction. Am J Physiol Endocrinol Metab. 2007;293:E1716-25 pubmed publisher
  48. Cinkulov M, Popovski Z, Porcu K, Tanaskovska B, Hodzic A, Bytyqi H, et al. Genetic diversity and structure of the West Balkan Pramenka sheep types as revealed by microsatellite and mitochondrial DNA analysis. J Anim Breed Genet. 2008;125:417-26 pubmed publisher
    ..suggests that the West Balkan Pramenka sheep types have their origins in two distinct maternal lineages of domestic sheep and different Pramenka phenotypes tend to form few panmictic populations...
  49. Fauzi M, Lokanathan Y, Aminuddin B, Ruszymah B, Chowdhury S. Ovine tendon collagen: Extraction, characterisation and fabrication of thin films for tissue engineering applications. Mater Sci Eng C Mater Biol Appl. 2016;68:163-171 pubmed publisher
    ..In conclusion, ovine tendon could be an alternative source of col I to fabricate scaffold for tissue engineering applications. ..
  50. Thomas K, Toth J, Crawford N, Seim H, Shi L, Harris M, et al. Bioresorbable polylactide interbody implants in an ovine anterior cervical discectomy and fusion model: three-year results. Spine (Phila Pa 1976). 2008;33:734-42 pubmed publisher
    ..The use of polylactide as a cervical interbody device appears both safe and effective based on these ACDF animal model results. ..
  51. Samson N, Lafond J, Moreau Bussiere F, Reix P, Praud J. Cricothyroid muscle electrical activity during respiration and apneas in lambs. Respir Physiol Neurobiol. 2007;155:147-55 pubmed
    ..Our results concur with the assumption that CT behaves as a laryngeal dilator in the neonatal period. ..
  52. Kobayashi N, Ong K, Villarraga M, Schwardt J, Wenz R, Togawa D, et al. Histological and mechanical evaluation of self-setting calcium phosphate cements in a sheep vertebral bone void model. J Biomed Mater Res A. 2007;81:838-46 pubmed
    ..The barium sulfate did not affect the CPCs biocompatibility or mechanical properties. These results suggest that CPC might be a good alternative to polymethylmethacrylate for selected indications. ..
  53. Crossley K, Morley C, Allison B, Polglase G, Dargaville P, Harding R, et al. Blood gases and pulmonary blood flow during resuscitation of very preterm lambs treated with antenatal betamethasone and/or Curosurf: effect of positive end-expiratory pressure. Pediatr Res. 2007;62:37-42 pubmed
    ..These treatments do not alter the deleterious effects of high levels of PEEP on PBF. ..
  54. Thomas D, Wormald P. Standardization of diagnostic criteria for eosinophilic chronic rhinosinusitis in the Oestrus ovis infected sheep model. Am J Rhinol. 2007;21:551-5 pubmed
  55. Jen K, Dyson M, Lester P, Nemzek J. Pharmacokinetics of a Transdermal Fentanyl Solution in Suffolk Sheep (Ovis aries). J Am Assoc Lab Anim Sci. 2017;56:550-557 pubmed
    ..Caution and further study are required before the use of TFS in sheep can be recommended fully. ..
  56. Fernández Aguilar X, Cabezón O, Frey J, Velarde R, Serrano E, Colom Cadena A, et al. Long-term dynamics of Mycoplasma conjunctivae at the wildlife-livestock interface in the Pyrenees. PLoS ONE. 2017;12:e0186069 pubmed publisher
    ..was performed by qPCR on 3600 eye swabs collected during seven years from hunted wild ungulates and sympatric domestic sheep (n = 1800 animals), and cluster analyses of the strains were performed including previous reported local ..
  57. Munsick T, Peck D, Ritten J, Jones R, Jones M, Miller M. Expected Net Benefit of Vaccinating Rangeland Sheep against Bluetongue Virus Using a Modified-Live versus Killed Virus Vaccine. Front Vet Sci. 2017;4:166 pubmed publisher
    Recurring outbreaks of bluetongue virus in domestic sheep of the US Intermountain West have prompted questions about the economic benefits and costs of vaccinating individual flocks against bluetongue (BT) disease...
  58. Terefe G, Lacroux C, Andreoletti O, Grisez C, Prevot F, Bergeaud J, et al. Immune response to Haemonchus contortus infection in susceptible (INRA 401) and resistant (Barbados Black Belly) breeds of lambs. Parasite Immunol. 2007;29:415-24 pubmed
    ..contortus infection is a Th2-biased immunity in which the BBB showed its maximal performance during the primary infection, the INRA breed performed better after re-infection compared to its response to first exposure. ..
  59. Langrová I, Makovcová K, Vadlejch J, Jankovská I, Petrtýl M, Fechtner J, et al. Arrested development of sheep strongyles: onset and resumption under field conditions of Central Europe. Parasitol Res. 2008;103:387-92 pubmed publisher
    ..The analysis of influences of various environmental factors revealed that the number of arrested larvae was negatively influenced by light-day length, sunshine, or daylight decrease (p < 0.01)...
  60. Agça E, Batailler M, Tillet Y, Chemineau P, Duittoz A. Modulation of estrogen receptors during development inhibits neurogenesis of precursors to GnRH-1 neurones: in vitro studies with explants of ovine olfactory placode. Brain Res. 2008;1223:34-41 pubmed publisher
  61. Schmidt M, Jaeggi E, Ryan G, Hyldebrandt J, Lilly J, Peirone A, et al. Percutaneous ultrasound-guided stenting of the atrial septum in fetal sheep. Ultrasound Obstet Gynecol. 2008;32:923-8 pubmed publisher
    ..Partial luminal occlusion by rapid proliferation of endocardial cells is a concern. ..
  62. Smith K, Abrahams P, Dagleish M, Steigmajer J. The intake of lead and associated metals by sheep grazing mining-contaminated floodplain pastures in mid-Wales, UK: I. Soil ingestion, soil-metal partitioning and potential availability to pasture herbage and livestock. Sci Total Environ. 2009;407:3731-9 pubmed publisher
  63. Oliveira R, Mousel M, Pabilonia K, Highland M, Taylor J, Knowles D, et al. Domestic sheep show average Coxiella burnetii seropositivity generations after a sheep-associated human Q fever outbreak and lack detectable shedding by placental, vaginal, and fecal routes. PLoS ONE. 2017;12:e0188054 pubmed publisher
    ..S. sheep placental C. burnetii shedding update in over 60 years and demonstrate potential for C. burnetii shedding to reach undetectable levels after an outbreak event even in the absence of targeted interventions, such as vaccination...
  64. Santiago Moreno J, Gonzalez Bulnes A, Gomez Brunet A, Toledano Díaz A, Lopez Sebastian A. Prediction of gestational age by transrectal ultrasonographic measurements in the mouflon (Ovis gmelini musimon). J Zoo Wildl Med. 2005;36:457-62 pubmed
    ..94) were the crown-rump and occipito-snout lengths and the thoracic and biparietal diameters. No significant differences were observed in pregnancies with one or two fetuses in the period studied. ..
  65. Kaeuffer R, Coltman D, Chapuis J, Pontier D, Reale D. Unexpected heterozygosity in an island mouflon population founded by a single pair of individuals. Proc Biol Sci. 2007;274:527-33 pubmed
    ..This study shows the importance of longitudinal genetic surveys for understanding the mechanisms that regulate genetic diversity in wild populations. ..
  66. Bartova E, Sedlak K, Pavlik I, Literak I. Prevalence of Neospora caninum and Toxoplasma gondii antibodies in wild ruminants from the countryside or captivity in the Czech Republic. J Parasitol. 2007;93:1216-8 pubmed publisher
    ..caninum. This is the first evidence of N. caninum infection in mouflon, the first N. caninum seroprevalence study in farmed red deer, and the first survey of N. caninum in wild ruminants from the Czech Republic...
  67. Redwan e, Fahmy A, El Hanafy A, Abd El Baky N, Sallam S. Ovine anti-rabies antibody production and evaluation. Comp Immunol Microbiol Infect Dis. 2009;32:9-19 pubmed publisher
    ..Sheep's IgG has low immunogenic effect than human and horse antibodies when injected into the mouse. Pure concentrated ovine antibody may serve as a possible alternative to currently available anti-rabies human or equine immunoglobulin. ..
  68. Upile T, Jerjes W, Mahil J. Q fever-related otological manifestations following chronic exposure to products of conception?. Br J Dermatol. 2008;158:1389 pubmed publisher
  69. Candela M, Caballol A, Atance P. Wide exposure to Coxiella burnetii in ruminant and feline species living in a natural environment: zoonoses in a human-livestock-wildlife interface. Epidemiol Infect. 2017;145:478-481 pubmed publisher
    ..Observed C. burnetii seropositive frequencies were: 33·3% European wildcats, 23·8% Spanish ibex, 22·5% domestic sheep 1·5% red deer, 1·4% European mouflon, 0·24% cattle, 0·18% fallow deer and 0% roe deer...
  70. Fujishiro T, Bauer T, Kobayashi N, Kobayashi H, Sunwoo M, Seim H, et al. Histological evaluation of an impacted bone graft substitute composed of a combination of mineralized and demineralized allograft in a sheep vertebral bone defect. J Biomed Mater Res A. 2007;82:538-44 pubmed
    ..The AFT preparation of a mixture of mineralized and demineralized allograft appears to be an effective autograft substitute as tested in this sheep vertebral bone void model. ..
  71. Ma L, Yang L, Zhang Y, Cao J, Hua S, Li J. Quantitative analysis of mitochondrial RNA in goat-sheep cloned embryos. Mol Reprod Dev. 2008;75:33-9 pubmed
    ..Moreover, we strongly argued a mechanism, that is GFF-derived mitochondria were degraded for the depression of bioenergetic functions, and then selectively eliminated during the embryogenesis of goat-sheep cloned embryos. ..
  72. Wu Z, Wei L, Hu Y, Wang H, Wan S, Wang J, et al. Staged-injection procedure to prevent cement leakage during vertebroplasty: an in vitro study. Spine (Phila Pa 1976). 2007;32:2437-42 pubmed
    ..Slow release of bBMP using FS appeared to be an effective method of protein delivery. The use of bBMP/FS in the treatment of vertebral osteoporosis in an attempt to enhance bone strength merits further study. ..
  73. Vaccarelli G, Miccoli M, Antonacci R, Pesole G, Ciccarese S. Genomic organization and recombinational unit duplication-driven evolution of ovine and bovine T cell receptor gamma loci. BMC Genomics. 2008;9:81 pubmed publisher
    ..We propose that only duplications of entire J-J-C regions that possessed an enhancer-like element at their 3' end, and acquired at least one V segment at their 5' end, were selected and fixed as functional recombinational units. ..
  74. Karioti A, Hatzoglou C, Zarogiannis S, Deligiorgi T, Liakopoulos V, Kourti P, et al. Rapid effect of dexamethasone on the permeability of visceral sheep peritoneum. Adv Perit Dial. 2008;24:2-6 pubmed
    ..The rapid effect implicates dexamethasone and probably mifepristone as being involved in a common nongenomic pathway. Further investigation is necessary to elucidate the underlying mechanisms and perspectives of these findings. ..
  75. Fletouris D, Papapanagiotou E, Nakos D. Liquid chromatographic determination and depletion profile of oxytetracycline in milk after repeated intramuscular administration in sheep. J Chromatogr B Analyt Technol Biomed Life Sci. 2008;876:148-52 pubmed publisher
    ..6%, respectively. The method was successfully applied to study the depletion of oxytetracycline in sheep milk and to estimate the withdrawal period after intramuscular administration of a commercial oxytetracycline formulation. ..
  76. Ozgul A, Tuljapurkar S, Benton T, Pemberton J, Clutton Brock T, Coulson T. The dynamics of phenotypic change and the shrinking sheep of St. Kilda. Science. 2009;325:464-7 pubmed publisher
    ..Our results enable us to explain why selection has so little effect even though weight is heritable, and why environmental change has caused a decline in the body size of Soay sheep. ..
  77. Petit M, Astruc J, Sarry J, Drouilhet L, Fabre S, Moreno C, et al. Variation in Recombination Rate and Its Genetic Determinism in Sheep Populations. Genetics. 2017;207:767-784 pubmed publisher
    ..The comparison of these new results to those obtained previously in a distantly related population of domestic sheep (the Soay) revealed that Soay and Lacaune males have a very similar distribution of recombination along the ..
  78. Nicholson E, Richt J, Rasmussen M, Hamir A, Lebepe Mazur S, Horst R. Exposure of sheep scrapie brain homogenate to rumen-simulating conditions does not result in a reduction of PrP(Sc) levels. Lett Appl Microbiol. 2007;44:631-6 pubmed
    ..This result implicates other developmental changes that are responsible for the age-dependent susceptibility of cattle to BSE. ..
  79. Arregui L, Rathi R, Megee S, Honaramooz A, Gomendio M, Roldan E, et al. Xenografting of sheep testis tissue and isolated cells as a model for preservation of genetic material from endangered ungulates. Reproduction. 2008;136:85-93 pubmed publisher
    ..To assess the potential use of these techniques in endangered bovid species, the domestic sheep was used as a model...
  80. McCarty R, Gronthos S, Zannettino A, Foster B, Xian C. Characterisation and developmental potential of ovine bone marrow derived mesenchymal stem cells. J Cell Physiol. 2009;219:324-33 pubmed publisher
    ..The comprehensive characterisation of ovine MSC described herein provides important information for future translational studies involving ovine MSC. ..
  81. Caporale M, Cousens C, Centorame P, Pinoni C, de las Heras M, Palmarini M. Expression of the jaagsiekte sheep retrovirus envelope glycoprotein is sufficient to induce lung tumors in sheep. J Virol. 2006;80:8030-7 pubmed publisher
    ..These data strongly suggest that the JSRV Env functions as a dominant oncoprotein in the natural immunocompetent host and that JSRV can induce OPA in the absence of viral spread...
  82. Tomimatsu T, Pena J, Longo L. Fetal cerebral oxygenation: the role of maternal hyperoxia with supplemental CO2 in sheep. Am J Obstet Gynecol. 2007;196:359.e1-5 pubmed
    ..CO2 supplementation of maternal O2 administration enhanced fetal cerebral oxygenation. In contrast, it was considered that during labor maternal hyperventilation with hypocapnia may blunt the effect of maternal O2 inhalation. ..
  83. Pfeffer A, Morris C, Green R, Wheeler M, Shu D, Bisset S, et al. Heritability of resistance to infestation with the body louse, Bovicola ovis, in Romney sheep bred for differences in resistance or resilience to gastro-intestinal nematode parasites. Int J Parasitol. 2007;37:1589-97 pubmed
    ..These results suggest that selective breeding would be effective in reducing louse infestation and cockle in sheep, but that differences in louse burdens were not related to differences in nematode burdens as indicated by FECs. ..
  84. Kobayashi H, Fujishiro T, Belkoff S, Kobayashi N, Turner A, Seim H, et al. Long-term evaluation of a calcium phosphate bone cement with carboxymethyl cellulose in a vertebral defect model. J Biomed Mater Res A. 2009;88:880-8 pubmed publisher
    ..There was variability among animals, but histology suggests that considerable cement was still present in most samples after 36 months. ..
  85. Psaltis P, Carbone A, Nelson A, Lau D, Manavis J, Finnie J, et al. An ovine model of toxic, nonischemic cardiomyopathy--assessment by cardiac magnetic resonance imaging. J Card Fail. 2008;14:785-95 pubmed publisher
    ..CMR provides a powerful tool for assessing myocardial function, structural remodeling, and viability in such models. ..
  86. Gutiérrez Gil B, Perez J, Alvarez L, Martínez Valladares M, De La Fuente L, Bayon Y, et al. Quantitative trait loci for resistance to trichostrongylid infection in Spanish Churra sheep. Genet Sel Evol. 2009;41:46 pubmed publisher
    ..The most significant QTL identified on chromosome 6 for LFEC(1) may be the target for future fine-mapping research efforts. ..
  87. Laurent A, Wassef M, Saint Maurice J, Namur J, Pelage J, Seron A, et al. Arterial distribution of calibrated tris-acryl gelatin and polyvinyl alcohol microspheres in a sheep kidney model. Invest Radiol. 2006;41:8-14 pubmed
    ..001) and for each caliber of injected microspheres (P < 0.001 each). The repartition of a spherical embolic agent in a given vascular network can be influenced by its size and also by its deformation within the vascular bed. ..
  88. Torgerson P, Oguljahan B, Muminov A, Karaeva R, Kuttubaev O, Aminjanov M, et al. Present situation of cystic echinococcosis in Central Asia. Parasitol Int. 2006;55 Suppl:S207-12 pubmed
    ..Village and urban dogs have a considerably lower prevalence. ..
  89. De Buys Roessingh A, De Lagausie P, Barbet J, Mercier J, Aigrain Y, Dinh Xuan A. Role of ATP-dependent potassium channels in pulmonary vascular tone of fetal lambs with congenital diaphragmatic hernia. Pediatr Res. 2006;60:537-42 pubmed
    ..We conclude that activation of K(ATP) channels could be of interest to reduce pulmonary vascular tone in fetal lambs with CDH, a condition often associated with persistent pulmonary hypertension of the newborn. ..
  90. Flecknoe S, Crossley K, Zuccala G, Searle J, Allison B, Wallace M, et al. Increased lung expansion alters lung growth but not alveolar epithelial cell differentiation in newborn lambs. Am J Physiol Lung Cell Mol Physiol. 2007;292:L454-61 pubmed
    ..This study demonstrates that increases in end-expiratory lung volumes, induced by the application of PEEP, lead to increased lung growth in mechanically ventilated 2-wk-old lambs but do not alter the proportions of AECs. ..
  91. Nandi S, Kumar V, Manjunatha B, Gupta P. Biochemical composition of ovine follicular fluid in relation to follicle size. Dev Growth Differ. 2007;49:61-6 pubmed
    ..As follicles became larger, the concentrations of glucose and cholesterol significantly (P < 0.05) increased while those of triglycerides, lactate, alkaline phosphatase and lactate dehydrogenase significantly (P < 0.05) decreased. ..
  92. Cai Y, Wang Q, He Y, Pan L. Interlaboratory validation of a real-time PCR detection method for bovine- and ovine-derived material. Meat Sci. 2017;134:119-123 pubmed publisher