tetraodontiformes

Summary

Summary: A small order of primarily marine fish containing 340 species. Most have a rotund or box-like shape. TETRODOTOXIN is found in their liver and ovaries.

Top Publications

  1. Yap W, Tay A, Brenner S, Venkatesh B. Molecular cloning of the pufferfish (Takifugu rubripes) Mx gene and functional characterization of its promoter. Immunogenetics. 2003;54:705-13 pubmed
    ..Deletion analysis of the promoter showed that both ISREs contributed to inducibility. These results demonstrate that the molecular mechanisms involved in Mx gene regulation are conserved between fish and mammals. ..
  2. Lee J, Kondo H, Sato S, Akimoto S, Saito T, Kodama M, et al. Identification of novel genes related to tetrodotoxin intoxication in pufferfish. Toxicon. 2007;49:939-53 pubmed
    ..Relative mRNA levels of flp-1, flp-2 and flp-3 showed a linear correlation with toxicity of the liver for two pufferfish species...
  3. Lin C, Tsai R, Lee T. Expression and distribution of Na, K-ATPase in gill and kidney of the spotted green pufferfish, Tetraodon nigroviridis, in response to salinity challenge. Comp Biochem Physiol A Mol Integr Physiol. 2004;138:287-95 pubmed
  4. Chen W, Orti G, Meyer A. Novel evolutionary relationship among four fish model systems. Trends Genet. 2004;20:424-31 pubmed
    ..cichlids (Perciformes) appear to be more closely related to each other than either of them is to pufferfish (Tetraodontiformes), suggesting that a re-interpretation of some findings in comparative biology might be required...
  5. Fairbrother W, Yeo G, Yeh R, Goldstein P, Mawson M, Sharp P, et al. RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons. Nucleic Acids Res. 2004;32:W187-90 pubmed
    ..mit.edu/burgelab/rescue-ese/) that annotates RESCUE-ESE hexamers in vertebrate exons and can be used to predict splicing phenotypes by identifying sequence changes that disrupt or alter predicted ESEs...
  6. Van de Peer Y. Tetraodon genome confirms Takifugu findings: most fish are ancient polyploids. Genome Biol. 2004;5:250 pubmed
    ..Ray-finned fish underwent a whole-genome duplication some 350 million years ago that might explain their evolutionary success...
  7. Britz R, Johnson G. Occipito-vertebral fusion in ocean sunfishes (Teleostei: Tetraodontiformes: Molidae) and its phylogenetic implications. J Morphol. 2005;266:74-9 pubmed
    ..We conclude that the shared occipito-vertebral fusion in molids and ostraciids and its otherwise extremely rare occurrence among teleosts provide support for a sister-group relationship of the two families...
  8. Chowdhury F, Nazmul Ahasan H, Mamunur Rashid A, Al Mamun A, Khaliduzzaman S. Tetrodotoxin poisoning: a clinical analysis, role of neostigmine and short-term outcome of 53 cases. Singapore Med J. 2007;48:830-3 pubmed
    ..In this paper, we aim to share our experience and to find out the toxic manifestations, lag period between ingestion of fish and development of symptoms, the short-term clinical outcome, and value of neostigmine in its management...
  9. Bentur Y, Ashkar J, Lurie Y, Levy Y, Azzam Z, Litmanovich M, et al. Lessepsian migration and tetrodotoxin poisoning due to Lagocephalus sceleratus in the eastern Mediterranean. Toxicon. 2008;52:964-8 pubmed publisher
    ..The Suez Canal permits migration of fish from the Indo-Pacific Ocean to the Mediterranean Sea. This phenomenon (Lessepsian migration) has enabled poisonous fish species to colonize the Mediterranean Sea...

More Information

Publications63

  1. Gottgens B, Barton L, Chapman M, Sinclair A, Knudsen B, Grafham D, et al. Transcriptional regulation of the stem cell leukemia gene (SCL)--comparative analysis of five vertebrate SCL loci. Genome Res. 2002;12:749-59 pubmed
    ..Analysis of the SCL promoter/enhancer revealed five motifs, which were conserved from zebrafish to mammals, and each of which is essential for the appropriate pattern or level of SCL transcription...
  2. Bagherie Lachidan M, Wright S, Kelly S. Claudin-8 and -27 tight junction proteins in puffer fish Tetraodon nigroviridis acclimated to freshwater and seawater. J Comp Physiol B. 2009;179:419-31 pubmed publisher
    ..These data provide some insight into the duplication history of cldn8 and cldn27 genes in fishes and suggest a possible role for claudin-8 and -27 proteins in the osmoregulatory strategies of euryhaline teleosts...
  3. Ngy L, Tada K, Yu C, Takatani T, Arakawa O. Occurrence of paralytic shellfish toxins in Cambodian Mekong pufferfish Tetraodon turgidus: selective toxin accumulation in the skin. Toxicon. 2008;51:280-8 pubmed
    ..turgidus are derived from an exogenous origin, and are selectively transferred via the blood into the skin, where the toxins accumulate...
  4. Yu C, Yu P. The annual toxicological profiles of two common puffer fish, Takifugu niphobles (Jordan and Snyder) and Takifugu alboplumbeus (Richardson), collected along Hong Kong coastal waters. Toxicon. 2002;40:313-6 pubmed
    ..Contrary to the most common belief, both species were discovered to be relatively less toxic during their spawning seasons...
  5. Yamanoue Y, Miya M, Inoue J, Matsuura K, Nishida M. The mitochondrial genome of spotted green pufferfish Tetraodon nigroviridis (Teleostei: Tetraodontiformes) and divergence time estimation among model organisms in fishes. Genes Genet Syst. 2006;81:29-39 pubmed
    ..the whole mitochondrial genome sequence for spotted green pufferfish, Tetraodon nigroviridis (Teleostei: Tetraodontiformes)...
  6. Nakagawa T, Jang J, Yotsu Yamashita M. Hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry of tetrodotoxin and its analogs. Anal Biochem. 2006;352:142-4 pubmed
  7. Steinke D, Salzburger W, Braasch I, Meyer A. Many genes in fish have species-specific asymmetric rates of molecular evolution. BMC Genomics. 2006;7:20 pubmed
  8. Kono M, Matsui T, Furukawa K, Takase T, Yamamori K, Kaneda H, et al. Examination of transformation among tetrodotoxin and its analogs in the living cultured juvenile puffer fish, kusafugu, Fugu niphobles by intramuscular administration. Toxicon. 2008;52:714-20 pubmed publisher
    ..Transformations from TTX to deoxy analogs or 11-oxoTTX, or from 11-oxoTTX to TTX were not detected in this study...
  9. Santini F, Sorenson L, Marcroft T, Dornburg A, Alfaro M. A multilocus molecular phylogeny of boxfishes (Aracanidae, Ostraciidae; Tetraodontiformes). Mol Phylogenet Evol. 2013;66:153-60 pubmed publisher
    Boxfishes (superfamily Ostracioidea, order Tetraodontiformes) are comprised of 37 species within the families Aracanidae (13 sp.) and Ostracidae (24 sp.)...
  10. Horie M, Kobayashi S, Shimizu N, Nakazawa H. Determination of tetrodotoxin in puffer-fish by liquid chromatography-electrospray ionization mass spectrometry. Analyst. 2002;127:755-9 pubmed
    ..The recoveries of the tetrodotoxin from the puffer-fish fortified at 1 microg g(-1) were 77.7-80.7% and the detection limit was 0.1 microg g(-1) (equivalent to ca. 0.5 mouse units per gram)...
  11. Isbister G, Son J, Wang F, Maclean C, Lin C, Ujma J, et al. Puffer fish poisoning: a potentially life-threatening condition. Med J Aust. 2002;177:650-3 pubmed
    ..Symptoms of poisoning may include paralysis, respiratory failure, numbness, paraesthesia, nausea and ataxia. Health professionals should be aware of the condition so as to institute early and appropriate management...
  12. Neafsey D, Palumbi S. Genome size evolution in pufferfish: a comparative analysis of diodontid and tetraodontid pufferfish genomes. Genome Res. 2003;13:821-30 pubmed
    ..We comment on the role that large insertions may play in the evolution of genome size in these two groups...
  13. Yamanoue Y, Miya M, Matsuura K, Katoh M, Sakai H, Nishida M. A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: basal ecological diversification?. BMC Evol Biol. 2008;8:212 pubmed publisher
    The order Tetraodontiformes consists of approximately 429 species of fishes in nine families...
  14. Bagherie Lachidan M, Wright S, Kelly S. Claudin-3 tight junction proteins in Tetraodon nigroviridis: cloning, tissue-specific expression, and a role in hydromineral balance. Am J Physiol Regul Integr Comp Physiol. 2008;294:R1638-47 pubmed publisher
  15. Nagashima Y, Toyoda M, Hasobe M, Shimakura K, Shiomi K. In vitro accumulation of tetrodotoxin in pufferfish liver tissue slices. Toxicon. 2003;41:569-74 pubmed
    ..These results suggest that the difference in the accumulation of TTX between pufferfish and filefish livers is ascribable to the difference not in the TTX excreting ability but in the ability to take up TTX...
  16. Ikeda K, Emoto Y, Tatsuno R, Wang J, Ngy L, Taniyama S, et al. Maturation-associated changes in toxicity of the pufferfish Takifugu poecilonotus. Toxicon. 2010;55:289-97 pubmed publisher
  17. Hallikas O, Palin K, Sinjushina N, Rautiainen R, Partanen J, Ukkonen E, et al. Genome-wide prediction of mammalian enhancers based on analysis of transcription-factor binding affinity. Cell. 2006;124:47-59 pubmed
  18. Tanu M, Mahmud Y, Arakawa O, Takatani T, Kajihara H, Kawatsu K, et al. Immunoenzymatic visualization of tetrodotoxin (TTX) in Cephalothrix species (Nemertea: Anopla: Palaeonemertea: Cephalotrichidae) and Planocera reticulata (Platyhelminthes: Turbellaria: Polycladida: Planoceridae). Toxicon. 2004;44:515-20 pubmed
    ..On the other hand, the hermaphrodite flatworm P. reticulata exhibited TTX antigen-antibody complex only in their ovum. To our knowledge, this is the first experimental effort on micro-distribution of TTX in invertebrates...
  19. Yeo G, Hoon S, Venkatesh B, Burge C. Variation in sequence and organization of splicing regulatory elements in vertebrate genes. Proc Natl Acad Sci U S A. 2004;101:15700-5 pubmed
  20. Campbell S, Harada R, DeFelice S, Bienfang P, Li Q. Bacterial production of tetrodotoxin in the pufferfish Arothron hispidus. Nat Prod Res. 2009;23:1630-40 pubmed publisher
    ..Among these sixteen bacterial species, Vibrio harveyi strains isolated from the skin slime and kidneys of A. hispidus were found to produce TTX, being the source of TTX produced in the pufferfish...
  21. Jang J, Lee J, Yotsu Yamashita M. LC/MS analysis of tetrodotoxin and its deoxy analogs in the marine puffer fish Fugu niphobles from the southern coast of Korea, and in the brackishwater puffer fishes Tetraodon nigroviridis and Tetraodon biocellatus from Southeast Asia. Mar Drugs. 2010;8:1049-58 pubmed publisher
    ..niphobles, this analog was minor in the two Tetraodon species and Japanese F. pardalis. Among the tissues of F. niphobles, the concentrations of TTXs were highest in the ovaries (female) and skin (female and male)...
  22. Nakashima K, Arakawa O, Taniyama S, Nonaka M, Takatani T, Yamamori K, et al. Occurrence of saxitoxins as a major toxin in the ovary of a marine puffer Arothron firmamentum. Toxicon. 2004;43:207-12 pubmed
    ..In the analyses, saxitoxin (STX) and decarbamoylSTX (dcSTX) were identified as the major toxins in the ovary, while the skin contained only TTX...
  23. Oliveira J, Fernandes S, Schwartz C, Bloch C, Melo J, Rodrigues Pires O, et al. Toxicity and toxin identification in Colomesus asellus, an Amazonian (Brazil) freshwater puffer fish. Toxicon. 2006;48:55-63 pubmed
    ..6+/-0 5MU/g). The HPLC profile showed no traces of TTX, but only the presence of PSPs (STX, GTX 2 and GTX 3). These toxins were also confirmed by electrospray ionization mass spectrometry...
  24. Shin Jung L, Liao C, Arakawa O, Noguchi T, Hwang D. Toxicities of two freshwater puffers in Taiwan. J Nat Toxins. 2002;11:103-10 pubmed
    ..Analyses by electrophoresis, thin layer chromatography, and high performance liquid chromatography showed that the toxin from both species was composed of tetrodotoxin and anhydrotetrodotoxin...
  25. Yu C, Yu P, Chan P, Yan Q, Wong P. Two novel species of tetrodotoxin-producing bacteria isolated from toxic marine puffer fishes. Toxicon. 2004;44:641-7 pubmed
    ..3 to 105.3 mouse units (MU) in 500 ml of broth medium by mouse bioassay. The principal toxic component in the bacterial cultures was determined to be TTX by thin layer chromatography and mass spectrometry...
  26. Diener M, Christian B, Ahmed M, Luckas B. Determination of tetrodotoxin and its analogs in the puffer fish Takifugu oblongus from Bangladesh by hydrophilic interaction chromatography and mass-spectrometric detection. Anal Bioanal Chem. 2007;389:1997-2002 pubmed
    ..TTX was predominant in skin, muscle and liver, whereas trideoxytetrodotoxin preponderated in the ovary. The toxicity of the various tissues was determined by a mouse bioassay...
  27. Grützner F, Roest Crollius H, Lütjens G, Jaillon O, Weissenbach J, Ropers H, et al. Four-hundred million years of conserved synteny of human Xp and Xq genes on three Tetraodon chromosomes. Genome Res. 2002;12:1316-22 pubmed
    ..Sequence data reported in this paper have been deposited in GenBank and assigned the following accession no: AJ308098.]..
  28. Sasaki K, Takayama Y, Tahara T, Anraku K, Ito Y, Akaike N. Quantitative analysis of toxin extracts from various tissues of wild and cultured puffer fish by an electrophysiological method. Toxicon. 2008;51:606-14 pubmed publisher
    ..We calculated the maximum edible amount for each tissue, assuming that the lethal dose of TTX is 1-10 microg/kg, and we found that the liver or ovary was edible in the case of cultured puffer fish...
  29. Nishikawa T, Isobe M. Synthesis of tetrodotoxin, a classic but still fascinating natural product. Chem Rec. 2013;13:286-302 pubmed publisher
    ..This account describes a brief history of tetrodotoxin research and an overview of our synthetic efforts toward tetrodotoxin with the underlying logic and strategy...
  30. Brainerd E, Slutz S, Hall E, Phillis R. Patterns of genome size evolution in tetraodontiform fishes. Evolution. 2001;55:2363-8 pubmed
    ..Small genome size (1.1-1.3 pg) also appears to have evolved independently in some members of Balistoidea (triggerfishes and filefishes) within Tetraodontiformes.
  31. García Ortega A. Nutrition and feeding research in the spotted rose snapper (Lutjanus guttatus) and bullseye puffer (Sphoeroides annulatus), new species for marine aquaculture. Fish Physiol Biochem. 2009;35:69-80 pubmed publisher
    ..In this paper, the results on nutrition and feeding research with both species are reviewed and research needs to support their commercial production in the region are discussed...
  32. Cohen N, Deeds J, Wong E, Hanner R, Yancy H, White K, et al. Public health response to puffer fish (Tetrodotoxin) poisoning from mislabeled product. J Food Prot. 2009;72:810-7 pubmed
  33. Wang J, Araki T, Tatsuno R, Nina S, Ikeda K, Hamasaki M, et al. Transfer profile of intramuscularly administered tetrodotoxin to artificial hybrid specimens of pufferfish, Takifugu rubripes and Takifugu niphobles. Toxicon. 2011;58:565-9 pubmed publisher
    ..These findings suggest that part of the TTX is first taken up in the liver and then transferred/accumulated in the skin in male specimens and in the ovary in female specimens...
  34. Islam Q, Razzak M, Islam M, Bari M, Basher A, Chowdhury F, et al. Puffer fish poisoning in Bangladesh: clinical and toxicological results from large outbreaks in 2008. Trans R Soc Trop Med Hyg. 2011;105:74-80 pubmed publisher
    ..To improve the management of this and other poisoning in Bangladesh, facilities for life-saving assisted ventilation and related training of healthcare personnel are urgently needed at all levels of the health system...
  35. Holcroft N. A molecular analysis of the interrelationships of tetraodontiform fishes (Acanthomorpha: Tetraodontiformes). Mol Phylogenet Evol. 2005;34:525-44 pubmed
    ..Total evidence and RAG1-only analyses recover a monophyletic Tetraodontiformes. However, the relationships recovered within the order differ, and none completely conform to previous ..
  36. Santini F, Sorenson L, Alfaro M. A new multi-locus timescale reveals the evolutionary basis of diversity patterns in triggerfishes and filefishes (Balistidae, Monacanthidae; Tetraodontiformes). Mol Phylogenet Evol. 2013;69:165-76 pubmed publisher
  37. Holcroft N. A molecular test of alternative hypotheses of tetraodontiform (Acanthomorpha: Tetraodontiformes) sister group relationships using data from the RAG1 gene. Mol Phylogenet Evol. 2004;32:749-60 pubmed
    Two primary competing hypotheses regarding the identity of the sister group of the order Tetraodontiformes exist. The first hypothesis holds that some or all acanthuroid fishes represent the sister of Tetraodontiformes...
  38. Alfaro M, Santini F, Brock C. Do reefs drive diversification in marine teleosts? Evidence from the pufferfishes and their allies (Order Tetraodontiformes). Evolution. 2007;61:2104-26 pubmed
  39. Nzoughet J, Campbell K, Barnes P, Cooper K, Chevallier O, Elliott C. Comparison of sample preparation methods, validation of an UPLC-MS/MS procedure for the quantification of tetrodotoxin present in marine gastropods and analysis of pufferfish. Food Chem. 2013;136:1584-9 pubmed publisher
    ..This study is the first report on the use of ASE as a mean for TTX extraction, the use of UPLC-MS/MS for TTX analysis, and the validation of this method for TTX in gastropods...
  40. Mahmud Y, Arakawa O, Ichinose A, Begum Tanu M, Takatani T, Tsuruda K, et al. Intracellular visualization of tetrodotoxin (TTX) in the skin of a puffer Tetraodon nigroviridis by immunoenzymatic technique. Toxicon. 2003;41:605-11 pubmed
    ..nigroviridis enters into the undifferentiated basal cells through diffusion, it is taken to the lysosomes by phagocytosis and exists there through binding with internal constituent(s) of the organelles...
  41. Lutfalla G, Roest Crollius H, Stange Thomann N, Jaillon O, Mogensen K, Monneron D. Comparative genomic analysis reveals independent expansion of a lineage-specific gene family in vertebrates: the class II cytokine receptors and their ligands in mammals and fish. BMC Genomics. 2003;4:29 pubmed
    ..Despite the report of a near complete pufferfish (Takifugu rubripes) genome sequence, these genes remain undescribed in fish...
  42. Iwata S, Matsuura T, Yamamoto S, Tahara T, Shin M, Ito Y, et al. Inhibition of Na currents by the toxin extracts from puffer fishes captured in the sea coast of Japan. Toxicon. 2010;56:999-1006 pubmed publisher
    ..rubripes, also eaten. This observation suggests that caution should be taken concerning the maximal edible amount of muscle prepared from T. rubripes...
  43. Yang G, Xu J, Liang S, Ren D, Yan X, Bao B. A novel TTX-producing Aeromonas isolated from the ovary of Takifugu obscurus. Toxicon. 2010;56:324-9 pubmed publisher
    ..obscurus, we propose that the TTX-producing Aeromonas sp. is a parasite or symbiotic bacterium rather than a sample contaminant. Collectively, our studies suggest that Aeromonas sp. strain Ne-1 produces tetrodotoxin in T. obscurus...
  44. Mulley J, Holland P. Comparative genomics: small genome, big insights. Nature. 2004;431:916-7 pubmed
  45. Johnson G, Britz R. Leis' conundrum: homology of the clavus of the ocean sunfishes. 2. Ontogeny of the median fins and axial skeleton of Ranzania laevis (Teleostei, Tetraodontiformes, Molidae). J Morphol. 2005;266:11-21 pubmed
    ..We thus conclude that the molid clavus is unequivocally formed by modified elements of the dorsal and anal fin and that the caudal fin is lost in molids...
  46. Woods I, Wilson C, Friedlander B, Chang P, Reyes D, Nix R, et al. The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. 2005;15:1307-14 pubmed
    ..In a three-way comparison between the genomes of zebrafish, Tetraodon, and human, our analysis delineates the gene content for 11 of these 12 proposed ancestral chromosomes...
  47. Noguchi T, Arakawa O. Tetrodotoxin--distribution and accumulation in aquatic organisms, and cases of human intoxication. Mar Drugs. 2008;6:220-42 pubmed publisher
    ..Several cases of TTX intoxication due to the ingestion of small gastropods, including some lethal cases, were recently reported in China and Taiwan, revealing a serious public health issue...
  48. Katikou P, Georgantelis D, Sinouris N, Petsi A, Fotaras T. First report on toxicity assessment of the Lessepsian migrant pufferfish Lagocephalus sceleratus (Gmelin, 1789) from European waters (Aegean Sea, Greece). Toxicon. 2009;54:50-5 pubmed publisher
    ..On the other hand, all tested extracts provided a positive reaction in the ELISA test for PSP toxins. This constitutes the first report for presence of toxicity in L. sceleratus caught in European coastal waters...
  49. Yamanoue Y, Miya M, Matsuura K, Yagishita N, Mabuchi K, Sakai H, et al. Phylogenetic position of tetraodontiform fishes within the higher teleosts: Bayesian inferences based on 44 whole mitochondrial genome sequences. Mol Phylogenet Evol. 2007;45:89-101 pubmed
    b>Tetraodontiformes includes approximately 350 species assigned to nine families, sharing several reduced morphological features of higher teleosts...
  50. Ahasan H, Mamun A, Karim S, Bakar M, Gazi E, Bala C. Paralytic complications of puffer fish (tetrodotoxin) poisoning. Singapore Med J. 2004;45:73-4 pubmed
    ..Puffer fish is available in Bangladesh and is occasionally eaten by some people. Ignorance regarding its proper cooking process may lead to serious health hazards, including fatality...
  51. Yamanoue Y, Miya M, Doi H, Mabuchi K, Sakai H, Nishida M. Multiple invasions into freshwater by pufferfishes (teleostei: tetraodontidae): a mitogenomic perspective. PLoS ONE. 2011;6:e17410 pubmed publisher
    Pufferfishes of the Family Tetraodontidae are the most speciose group in the Order Tetraodontiformes and mainly inhabit coastal waters along continents...
  52. Tanu M, Mahmud Y, Takatani T, Kawatsu K, Hamano Y, Arakawa O, et al. Localization of tetrodotoxin in the skin of a brackishwater puffer Tetraodon steindachneri on the basis of immunohistological study. Toxicon. 2002;40:103-6 pubmed
    ..Malpighian cells of the skin did not exhibit any TTX antigen. Neither gland nor enclosed gland-like apparatus possessing TTX was apparent in the skin...
  53. Maruta S, Yamaoka K, Yotsu Yamashita M. Two critical residues in p-loop regions of puffer fish Na+ channels on TTX sensitivity. Toxicon. 2008;51:381-7 pubmed
    ..Despite drastic changes in the K(d), the mutations at F385 caused only small changes in the k(off) from that of WT, suggesting that the K(d) for TTX receptors are mainly determined by the k(on)...
  54. Roest Crollius H. The tetraodon genome. Genome Dyn. 2006;2:154-64 pubmed publisher