Summary: Small oviparous fishes in the family Cyprinodontidae, usually striped or barred black. They are much used in mosquito control.

Top Publications

  1. Setiamarga D, Miya M, Yamanoue Y, Mabuchi K, Satoh T, Inoue J, et al. Interrelationships of Atherinomorpha (medakas, flyingfishes, killifishes, silversides, and their relatives): The first evidence based on whole mitogenome sequences. Mol Phylogenet Evol. 2008;49:598-605 pubmed publisher
  2. Martin C, Wainwright P. Multiple fitness peaks on the adaptive landscape drive adaptive radiation in the wild. Science. 2013;339:208-11 pubmed publisher
    ..This complex landscape could explain both the rarity of specialists across many similar environments due to stabilizing selection on generalists and the rapid morphological diversification rate of specialists due to their higher fitness...
  3. Holtmeier C. Heterochrony, maternal effects, and phenotypic variation among sympatric pupfishes. Evolution. 2001;55:330-8 pubmed
    ..In Cyprinodon, small changes in multiple heterochronic parameters translate into large phenotypic differences in feeding morphology...
  4. Rosenfield J, Kodric Brown A. Sexual selection promotes hybridization between Pecos pupfish, Cyprinodon pecosensis and sheepshead minnow, C. variegatus. J Evol Biol. 2003;16:595-606 pubmed
  5. Hrbek T, Meyer A. Closing of the Tethys Sea and the phylogeny of Eurasian killifishes (Cyprinodontiformes: Cyprinodontidae). J Evol Biol. 2003;16:17-36 pubmed
    ..The two phylogenetically deepest events were also likely driven by ecological changes associated with the closing of the Tethys Sea...
  6. Litwiller S, O Donnell M, Wright P. Rapid increase in the partial pressure of NH3 on the cutaneous surface of air-exposed mangrove killifish, Rivulus marmoratus. J Exp Biol. 2006;209:1737-45 pubmed
    ..Together, these data indicate that during air exposure, R. marmoratus utilize the cutaneous surface as a key site of NH(3) volatilization...
  7. Agnese J, Zentz F, Legros O, Sellos D. Phylogenetic relationships and phylogeography of the Killifish species of the subgenus Chromaphyosemion (Radda, 1971) in West Africa, inferred from mitochondrial DNA sequences. Mol Phylogenet Evol. 2006;40:332-46 pubmed
    ..Phylogenetic relationships among the subgenus also revealed that chromosomal evolution is complex and should be studied at the intraspecific level...
  8. Taylor D, Turner B, Davis W, Chapman B. A novel terrestrial fish habitat inside emergent logs. Am Nat. 2008;171:263-6 pubmed publisher
    ..The dense packing of fish in the narrow log galleries may imply a novel social context in which intraspecific aggressive behaviors are reduced, possibly mediated by the physiological limitations imposed within this restrictive habitat...
  9. Martin C, Wainwright P. Trophic novelty is linked to exceptional rates of morphological diversification in two adaptive radiations of Cyprinodon pupfish. Evolution. 2011;65:2197-212 pubmed publisher
    ..We propose that the invasion of novel ecological niches may be a key mechanism driving many classic examples of adaptive radiation...

More Information

Publications154 found, 100 shown here

  1. Nacci D, Jayaraman S, Specker J. Stored retinoids in populations of the estuarine fish Fundulus heteroclitus indigenous to PCB-contaminated and reference sites. Arch Environ Contam Toxicol. 2001;40:511-8 pubmed
    ..These results are consistent with prior findings that fish from this contaminated site are relatively insensitive to some of the toxic effects of PCB exposures, including retinoid depletion. ..
  2. Zhou T, Rademacher D, Steinpreis R, Weis J. Neurotransmitter levels in two populations of larval Fundulus heteroclitus after methylmercury exposure. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1999;124:287-94 pubmed
    ..The changes in NT levels after exposure to MeHg are an indication of neurological dysfunction in larvae. ..
  3. Carson E, Dowling T. Influence of hydrogeographic history and hybridization on the distribution of genetic variation in the pupfishes Cyprinodon atrorus and C. bifasciatus. Mol Ecol. 2006;15:667-79 pubmed
    ..atrorus and mating site selection rather than selection for C. atrorus mitochondrial genome. These results demonstrate the important role hybridization can play in evolution. ..
  4. Erten Unal M, Gelderloos A, Hughes J. A toxicity reduction evaluation for an oily waste treatment plant exhibiting episodic effluent toxicity. Sci Total Environ. 1998;218:141-52 pubmed
    ..The results indicated that the cause of toxicity was most likely due to combination of pollutants (matrix effect) rather than a single pollutant. ..
  5. Duerr J, Podrabsky J. Mitochondrial physiology of diapausing and developing embryos of the annual killifish Austrofundulus limnaeus: implications for extreme anoxia tolerance. J Comp Physiol B. 2010;180:991-1003 pubmed publisher
  6. Lotufo G, Blackburn W, Gibson A. Toxicity of trinitrotoluene to sheepshead minnows in water exposures. Ecotoxicol Environ Saf. 2010;73:718-26 pubmed publisher
    ..3 micromol kg(-1)) for 2-ADNT and significant mortality occurred at 47.4 mg kg(-1)ww (283.6 micromol kg(-1)). The range of BCF values was from 1.8 to 2.4, 5.6 to 8.0, and 0.6 to 0.9Lkg(-1) for TNT, 2-ADNT, and 2,4-DANT, respectively. ..
  7. Flamarique I, Harosi F. Photoreceptors, visual pigments, and ellipsosomes in the killifish, Fundulus heteroclitus: a microspectrophotometric and histological study. Vis Neurosci. 2000;17:403-20 pubmed
    ..We propose that UV and S cones may be used to detect targets of interest against the background irradiance sensed by double cones. ..
  8. Jimenez M, Goodchild S, Stockwell C, Lema S. Characterization and phylogenetic analysis of complete mitochondrial genomes for two desert cyprinodontoid fishes, Empetrichthys latos and Crenichthys baileyi. Gene. 2017;626:163-172 pubmed publisher
    ..of central Mexico, and showed the combined clade of these fishes to be a sister group to the Profundulidae killifishes. Despite several significant life history and morphological differences between the Empetrichthyinae and ..
  9. Wagner J, Singh P, Romney A, Riggs C, Minx P, Woll S, et al. The genome of Austrofundulus limnaeus offers insights into extreme vertebrate stress tolerance and embryonic development. BMC Genomics. 2018;19:155 pubmed publisher
    ..genomics to determine the genetic and evolutionary mechanisms that support the unique biology of annual killifishes. In a broader context, this genome will be a valuable tool for exploring genome-environment interactions and ..
  10. Rowe C. Growth responses of an estuarine fish exposed to mixed trace elements in sediments over a full life cycle. Ecotoxicol Environ Saf. 2003;54:229-39 pubmed
  11. Johnson E, Weinersmith K, Earley R. Changes in reproductive physiology of mangrove rivulus Kryptolebias marmoratus following exposure to environmentally relevant doses of ethinyl oestradiol. J Fish Biol. 2016;88:774-86 pubmed publisher
    ..Exposure to EE2 resulted in a decrease in spermatid and spermatocyte density in males and an increase in the number of early stage oocytes in hermaphrodites. ..
  12. Hisatomi O, Imanishi Y, Satoh T, Tokunaga F. Arrestins expressed in killifish photoreceptor cells. FEBS Lett. 1997;411:12-8 pubmed
    ..It is speculated that the divergence pattern of vertebrate visual arrestins may prove to be reflected in the divergence of the proteins participating in the respective phototransduction cascades. ..
  13. Ellison A, Cable J, Consuegra S. Best of both worlds? Association between outcrossing and parasite loads in a selfing fish. Evolution. 2011;65:3021-6 pubmed publisher
    ..Moreover, our study provides evidence that parasites contribute to maintaining mixed-mating in a natural animal population. ..
  14. Eckerström Liedholm S, Sowersby W, Gonzalez Voyer A, Rogell B. Time-limited environments affect the evolution of egg-body size allometry. Evolution. 2017;71:1900-1910 pubmed publisher
    ..We tested this hypothesis in killifishes, and found a significantly steeper allometric relationship between egg and body sizes in annual, compared to ..
  15. Paladini G, Huyse T, Shinn A. Gyrodactylus salinae n. sp. (Platyhelminthes: Monogenea) infecting the south European toothcarp Aphanius fasciatus (Valenciennes) (Teleostei, Cyprinodontidae) from a hypersaline environment in Italy. Parasit Vectors. 2011;4:100 pubmed publisher
    ..These findings, together with the fact that A. fasciatus is a protected species and is considered as a biological control organism, necessitate further studies on the ecology and virulence of G. salinae n. sp. ..
  16. Vrtílek M, Žák J, Polačik M, Blažek R, Reichard M. Longitudinal demographic study of wild populations of African annual killifish. Sci Rep. 2018;8:4774 pubmed publisher
    ..Nothobranchius furzeri, a model species in ageing research, and two other species of coexisting annual killifishes. Annual killifish hatch synchronously, have non-overlapping generations, and reproduce daily after reaching ..
  17. Fournie J, Overstreet R. Host specificity of Calyptospora funduli (Apicomplexa: Calyptosporidae) in atheriniform fishes. J Parasitol. 1993;79:720-7 pubmed
    ..Additional barriers that limit natural infections of C. funduli in other hosts include feeding behavior, environmental conditions, and geographic isolation. ..
  18. Dzul M, Dixon P, Quist M, Dinsmore S, Bower M, Wilson K, et al. Using variance components to estimate power in a hierarchically nested sampling design. Environ Monit Assess. 2013;185:405-14 pubmed publisher
    ..This study provides an example of how monitoring efforts may benefit from coupling variance components estimation with power analysis to assess sampling design. ..
  19. Rice C, Xiang Y. Immune function, hepatic CYP1A, and reproductive biomarker responses in the gulf killifish, Fundulus grandis, during dietary exposures to endocrine disrupters. Mar Environ Res. 2000;50:163-8 pubmed
    ..This study underscores the need to consider normal physiological rhythms when employing biomarkers in toxicology. ..
  20. Reichenbacher B, Sienknecht U, Kuchenhoff H, Fenske N. Combined otolith morphology and morphometry for assessing taxonomy and diversity in fossil and extant killifish (Aphanius, Prolebias). J Morphol. 2007;268:898-915 pubmed
    ..for obtaining a better understanding of the taxonomy, diversity, and zoogeography of both fossil and extant killifishes. Moreover, the method may also be suitable for assessing taxonomy and diversity in other species-rich groups ..
  21. Rogowski D, Stockwell C. Parasites and salinity: costly tradeoffs in a threatened species. Oecologia. 2006;146:615-22 pubmed
    ..Although both high salinity and parasites significantly affect pupfish, parasites might be more detrimental. ..
  22. Lotufo G, Blackburn W, Marlborough S, Fleeger J. Toxicity and bioaccumulation of TNT in marine fish in sediment exposures. Ecotoxicol Environ Saf. 2010;73:1720-7 pubmed publisher
    ..Uptake from contact to sediment was likely negligible and bioaccumulation was from the overlying water. The feeding rate of FB exposed to 1700 ?mol kg(-1) sediment suspended in water for 24-h was significantly reduced by 50%. ..
  23. Amin O, Gholami Z, Akhlaghi M, Heckmann R. The description and host-parasite relationships of a new quadrigyrid species (Acanthocephala) from the Persian tooth-carp, Aphanius farsicus (Actinoptreygii: Cyprinodontidae) in Iran. J Parasitol. 2013;99:257-63 pubmed publisher
    ..While most worms were recovered in fish within the length range of 18-29.9 mm, 1 of the longest parasites (1.68 mm long) was found in fish within the range of 30-33.9 mm long. ..
  24. Keepers K, Martin A. Fitness landscape of sympatric pupfishes a useful tool for visualizing speciation. Mol Ecol. 2014;23:2144-5 pubmed publisher
    ..The article provides an illustrative example of the power afforded by analysis of large numbers of SNPs for estimating key parameters underlying evolutionary divergence. ..
  25. Tatarenkov A, Avise J. Rapid concerted evolution in animal mitochondrial DNA. Proc Biol Sci. 2007;274:1795-8 pubmed
    ..mediated by frequent gene conversion events, of duplicated sequences in the mtDNA control region of mangrove killifishes (Kryptolebias marmoratus)...
  26. Leaner J, Mason R. The effect of thiolate organic compounds on methylmercury accumulation and redistribution in sheepshead minnows, Cyprinodon variegatus. Environ Toxicol Chem. 2001;20:1557-63 pubmed
    ..The results of this study suggest that the CH3Hg-thiolate complexes were bioavailable to sheepshead minnows and effectively induced CH3Hg(II) uptake in tissues at environmentally realistic CH3HgCl concentrations. ..
  27. Podrabsky J, Somero G. An inducible 70 kDa-class heat shock protein is constitutively expressed during early development and diapause in the annual killifish Austrofundulus limnaeus. Cell Stress Chaperones. 2007;12:199-204 pubmed
    ..Constitutive expression of Hsp70 during development may afford these embryos protection from environmental stresses during development more quickly than relying on the induction of a classic heat shock response. ..
  28. Wallace R, Greeley M, McPherson R. Analytical and experimental studies on the relationship between Na+, K+, and water uptake during volume increases associated with Fundulus oocyte maturation in vitro. J Comp Physiol B. 1992;162:241-8 pubmed
    ..The ability of external K+ to promote follicle hydration was gradually lost during the maturation process as the oocyte dissociated from the surrounding granulosa cells in preparation for ovulation.(ABSTRACT TRUNCATED AT 250 WORDS) ..
  29. Podrabsky J, Hand S. Depression of protein synthesis during diapause in embryos of the annual killifish Austrofundulus limnaeus. Physiol Biochem Zool. 2000;73:799-808 pubmed
    ..The major depression of protein synthesis during diapause II affords a considerable reduction in energy demand and extends the duration of dormancy attainable in these embryos. ..
  30. Garcia G, Lalanne A, Aguirre G, Cappetta M. Chromosome evolution in the annual killifish genus Cynolebias and mitochondrial phylogenetic analysis. Chromosome Res. 2001;9:437-48 pubmed
    ..involving Robertsonian and non-Robertsonian changes were proposed to explain chromosomal evolution within killifishes of the aplocheiloid group belonging to the order Cyprinodontiforms...
  31. Kessabi K, Said K, Messaoudi I. Comparative study of longevity, growth, and biomarkers of metal detoxication and oxidative stress between normal and deformed Aphanius fasciatus (Pisces, Cyprinodontidae). J Toxicol Environ Health A. 2013;76:1269-81 pubmed publisher
    ..Taken together, oxidative stress, diminished longevity, and a disturbance of growth may be considered to be responsible factors contributing to spinal deformities. ..
  32. Klerks P, Moreau C. Heritability of resistance to individual contaminants and to contaminant mixtures in the sheepshead minnow (Cyprindon variegatus). Environ Toxicol Chem. 2001;20:1746-51 pubmed
    ..Our results mean, then, that C. variegatus in contaminated environments is not likely to become resistant to these contaminants very rapidly, and that resistance may develop even more slowly as more contaminants become involved. ..
  33. Williams N. Life in the fast lane. Curr Biol. 2003;13:R584 pubmed
  34. Podrabsky J, Lopez J, Fan T, Higashi R, Somero G. Extreme anoxia tolerance in embryos of the annual killifish Austrofundulus limnaeus: insights from a metabolomics analysis. J Exp Biol. 2007;210:2253-66 pubmed
    ..This is the first report of such extreme anoxia tolerance in a vertebrate embryo, and introduces a new model for the study of anoxia tolerance in vertebrates. ..
  35. Machado B, Podrabsky J. Salinity tolerance in diapausing embryos of the annual killifish Austrofundulus limnaeus is supported by exceptionally low water and ion permeability. J Comp Physiol B. 2007;177:809-20 pubmed
    ..limnaeus embryos acts as a permeability barrier to water and ions and supports osmoregulation in this species in response to a broad range of osmotic environments. ..
  36. Dasgupta S, DiGiulio R, Drollette B, L Plata D, Brownawell B, McElroy A. Hypoxia depresses CYP1A induction and enhances DNA damage, but has minimal effects on antioxidant responses in sheepshead minnow (Cyprinodon variegatus) larvae exposed to dispersed crude oil. Aquat Toxicol. 2016;177:250-60 pubmed publisher
    ..This study demonstrates the importance of considering hypoxia as an enhanced risk factor in assessing the effects of contaminants in areas where seasonal hypoxia may be prevalent. ..
  37. Nilsson H, Steffen W, Palazzo R. In vitro reconstitution of fish melanophore pigment aggregation. Cell Motil Cytoskeleton. 2001;48:1-10 pubmed
    ..The results show that dynein is essential for pigment aggregation and involved in maintenance of evenly dispersed pigment in vitro, analogous to cellular evidence, and suggest a possible role for dynactin in these processes as well. ..
  38. Carson E, Tobler M, Minckley W, Ainsworth R, Dowling T. Relationships between spatio-temporal environmental and genetic variation reveal an important influence of exogenous selection in a pupfish hybrid zone. Mol Ecol. 2012;21:1209-22 pubmed publisher
    ..atrorus and C. bifasciatus to previous demonstration of the long-term evolutionary significance of environmental variation and introgression on the phenotypic diversification Cuatro Ciénegas Cyprinodon. ..
  39. Vila I, Morales P, Scott S, Poulin E, Veliz D, Harrod C, et al. Phylogenetic and phylogeographic analysis of the genus Orestias (Teleostei: Cyprinodontidae) in the southern Chilean Altiplano: the relevance of ancient and recent divergence processes in speciation. J Fish Biol. 2013;82:927-43 pubmed publisher
    ..Diversification of Orestias in the southern Altiplano may be linked to historical vicariant events and contemporary variation in water level; these processes may have affected the populations from the Plio-Pleistocene until the present. ..
  40. Cerda J, Subhedar N, Reich G, Wallace R, Selman K. Oocyte sensitivity to serotonergic regulation during the follicular cycle of the teleost Fundulus heteroclitus. Biol Reprod. 1998;59:53-61 pubmed
  41. Blas Machado U, Taylor H, Means J. Apoptosis, PCNA, and p53 in Fundulus grandis fish liver after in vivo exposure to N-methyl-N'-nitro-N-nitrosoguanidine and 2-aminofluorene. Toxicol Pathol. 2000;28:601-9 pubmed
    ..Concurrent use of a marker for cell death with a marker of proliferation greatly enhances the assessment of the effect of these compounds on liver cells. ..
  42. Lüssen A, Falk T, Villwock W. Phylogenetic patterns in populations of Chilean species of the genus Orestias (Teleostei: Cyprinodontidae): results of mitochondrial DNA analysis. Mol Phylogenet Evol. 2003;29:151-60 pubmed
    ..No support was found for the utility of these data sets for inferring phylogenetic relationships between more distantly related taxa originating from Lake Titicaca. ..
  43. Hartmann N, Englert C. A microinjection protocol for the generation of transgenic killifish (Species: Nothobranchius furzeri). Dev Dyn. 2012;241:1133-41 pubmed publisher
    ..The feasibility to perform transgenesis is an important step to establish N. furzeri as a new model in age research. ..
  44. Polacik M, Donner M, Reichard M. Age structure of annual Nothobranchius fishes in Mozambique: is there a hatching synchrony?. J Fish Biol. 2011;78:796-809 pubmed publisher
    ..The hatching dates of sympatric Nothobranchius spp. were marginally different, but further testing on a larger sample is needed for conclusive results. ..
  45. Kessabi K, Annabi A, Navarro A, Casado M, Hwas Z, Said K, et al. Structural and molecular analysis of pollution-linked deformities in a natural Aphanius fasciatus (Valenciennes, 1821) population from the Tunisian coast. J Environ Monit. 2012;14:2254-60 pubmed publisher
  46. Esmaeili H, Ebrahimi M, Saifali M. Karyological analysis of five tooth-carps (Actinopterygii: Cyprinodontidae) from Iran. Micron. 2008;39:95-100 pubmed
    ..Cluster analysis revealed the closeness of A. sophiae and A. persicus. According to our data A. ginaonis is related to a group of A. sophiae+A. persicus+A. dispar. ..
  47. Raimondo S, Hemmer B, Goodman L, Cripe G. Multigenerational exposure of the estuarine sheepshead minnow (Cyprinodon variegatus) to 17?-estradiol. II. Population-level effects through two life cycles. Environ Toxicol Chem. 2009;28:2409-15 pubmed publisher
    ..Although population-level effects did not occur in the Fl generation, a risk decision based on Fl organism-level effects would be protective of the population exposed for two generations. ..
  48. Passos C, Tassino B, Loureiro M, Rosenthal G. Intra- and intersexual selection on male body size in the annual killifish Austrolebias charrua. Behav Processes. 2013;96:20-6 pubmed publisher
    ..The unique life-history of Austrolebias and the high repeatability of mate-choice assays make this system a promising candidate for studies of behavioural evolution. ..
  49. Richards E, Martin C. Adaptive introgression from distant Caribbean islands contributed to the diversification of a microendemic adaptive radiation of trophic specialist pupfishes. PLoS Genet. 2017;13:e1006919 pubmed publisher
    ..Our findings suggest that a suite of factors, including rare adaptive introgression, may be necessary for adaptive radiation in addition to ecological opportunity. ..
  50. Blanchard J, Grosell M. Effects of salinity on copper accumulation in the common killifish (Fundulus heteroclitus). Environ Toxicol Chem. 2005;24:1403-13 pubmed
    ..The present findings may have implications for future development of a BLM for saline environments by identifying potential target tissues. ..
  51. Rhee J, Seo J, Raisuddin S, Ki J, Lee K, Kim I, et al. Gonadotropin-releasing hormone receptor (GnRHR) gene expression is differently modulated in gender types of the hermaphroditic fish Kryptolebias marmoratus by endocrine disrupting chemicals. Comp Biochem Physiol C Toxicol Pharmacol. 2008;147:357-65 pubmed publisher
    ..This is the first report of a GnRHR gene from K. marmoratus and modulation of its expression by EDCs. This study provides an insight into the molecular mechanism of endocrinological functions of this unique fish. ..
  52. Rhee J, Kim B, Kang C, Lee Y, Lee J. Gamma irradiation-induced oxidative stress and developmental impairment in the hermaphroditic fish, Kryptolebias marmoratus embryo. Environ Toxicol Chem. 2012;31:1745-53 pubmed publisher
    ..The results of this study provide a better understanding of the molecular mode of action of gamma radiation in aquatic organisms. ..
  53. Hisatomi O, Satoh T, Tokunaga F. The primary structure and distribution of killifish visual pigments. Vision Res. 1997;37:3089-96 pubmed
    ..It is suggested that the relationships between the cell types and their respective visual pigment gene groups may be a common pattern among teleost fishes...
  54. Claiborne J, Blackston C, Choe K, Dawson D, Harris S, Mackenzie L, et al. A mechanism for branchial acid excretion in marine fish: identification of multiple Na+/H+ antiporter (NHE) isoforms in gills of two seawater teleosts. J Exp Biol. 1999;202:315-24 pubmed
    ..During systemic acidosis, apical gill NHE-2 (which is sensitive to external amiloride and low [Na+]) in parallel with a dramatic suppression of basolateral NHE-1 activity enhances net capdelta H+ transfers to the water. ..
  55. Davidson H, Taylor M, Doherty A, Boyd A, Porteous D. Genomic sequence analysis of Fugu rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7. Genome Res. 2000;10:1194-203 pubmed
    ..The euryhaline killifish CFTR coding sequence is highly homologous to the Fugu sequence, suggesting that upregulation of CFTR in that species in response to salinity may be regulated transcriptionally...
  56. Daborn K, Cozzi R, Marshall W. Dynamics of pavement cell-chloride cell interactions during abrupt salinity change in Fundulus heteroclitus. J Exp Biol. 2001;204:1889-99 pubmed
    ..We conclude that the actin cytoskeleton of chloride cells is required to maintain crypt opening and that osmotic shock causes chloride cells to adjust their apical crypt size. ..
  57. Strecker U. Genetic differentiation and reproductive isolation in a Cyprinodon fish species flock from Laguna Chichancanab, Mexico. Mol Phylogenet Evol. 2006;39:865-72 pubmed
    ..I propose that in the Cyprinodon species flock besides disruptive selection sexual selection plays an important part in achieving and maintaining reproductive isolation. ..
  58. Rodela T, Wright P. Metabolic and neuroendocrine effects on diurnal urea excretion in the mangrove killifish Rivulus marmoratus. J Exp Biol. 2006;209:2704-12 pubmed
    ..We propose that cortisol and 5-HT influence the absolute rate of urea excretion by altering the permeability of the gill membrane to urea and/or the rate of urea synthesis. ..
  59. Cripe G, Hemmer B, Goodman L, Fournie J, Raimondo S, Vennari J, et al. Multigenerational exposure of the estuarine sheepshead minnow (Cyprinodon variegatus) to 17 ?-estradiol. I. organism-level effects over three generations. Environ Toxicol Chem. 2009;28:2397-408 pubmed publisher
  60. Brix K, Grosell M. Comparative characterization of Na+ transport in Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi: a model species complex for studying teleost invasion of freshwater. J Exp Biol. 2012;215:1199-209 pubmed publisher
    ..v. hubbsi with the ability to osmoregulate in dilute freshwater. ..
  61. Brix K, Wood C, Grosell M. Measuring titratable alkalinity by single versus double endpoint titration: An evaluation in two cyprinodont species and implications for characterizing net H+ flux in aquatic organisms. Comp Biochem Physiol A Mol Integr Physiol. 2013;164:221-8 pubmed publisher
    ..5. However, significant differences between the double endpoint (no net H(+) transport at low pH) and single endpoint titrations (net H(+) uptake at low pH) remain to be explained. ..
  62. Martin C, Crawford J, Turner B, Simons L. Diabolical survival in Death Valley: recent pupfish colonization, gene flow and genetic assimilation in the smallest species range on earth. Proc Biol Sci. 2016;283: pubmed publisher
  63. Crawford D, Segal J, Barnett J. Evolutionary analysis of TATA-less proximal promoter function. Mol Biol Evol. 1999;16:194-207 pubmed
  64. Scott G, Fulton M, Moore D, Wirth E, Chandler G, Key P, et al. Assessment of risk reduction strategies for the management of agricultural nonpoint source pesticide runoff in estuarine ecosystems. Toxicol Ind Health. 1999;15:200-13 pubmed
    ..These findings clearly indicate the value of an integrated risk reduction strategy (BMP, IPM, and RP) for minimizing impacts from NPS agricultural pesticide runoff. ..
  65. Kreiser B, Mitton J, Woodling J. Phylogeography of the plains killifish, Fundulus zebrinus. Evolution. 2001;55:339-50 pubmed
    ..The large phylogenetic break between the northern/central and southern clades supports previous attempts to recognize two species of plains killifish: F. zebrinus and F. kansae. ..
  66. Perdices A, Carmona J, Fernández Delgado C, Doadrio I. Nuclear and mitochondrial data reveal high genetic divergence among Atlantic and Mediterranean populations of the Iberian killifish Aphanius iberus (Teleostei: Cyprinodontidae). Heredity (Edinb). 2001;87:314-24 pubmed
  67. Karels A, Brouwer M. Cloning, sequencing and phylogenetic/phenetic classification of an estrogen receptor alpha (alpha) subtype of sheepshead minnow (Cyprinodon variegatus). Comp Biochem Physiol B Biochem Mol Biol. 2003;135:263-72 pubmed
    ..Because ER alpha was the only subtype found, it appears that the alpha-subtype is predominant in C. variegatus liver. ..
  68. Leiser J, Itzkowitz M. Changing tactics: dominance, territoriality, and the responses of "primary" males to competition from conditional breeders in the variegated pupfish (Cyprinodon variegatus). Behav Processes. 2004;66:119-30 pubmed
    ..These results suggested that primary males, like conditional breeders, would adopt the tactic that enabled them to spawn despite the constraints of competition. ..
  69. Varo I, Amat F, Navarro J. Acute toxicity of dichlorvos to Aphanius iberus (Cuvier & Valenciennes, 1846) and its anti-cholinesterase effects on this species. Aquat Toxicol. 2008;88:53-61 pubmed publisher
    ..The results of this study show that ChE activity is a good biomarker of exposure to OP in the Iberian toothcarp adults. ..
  70. Yu I, Rhee J, Raisuddin S, Lee J. Characterization of the glutathione S-transferase-Mu (GSTM) gene sequence and its expression in the hermaphroditic fish, Kryptolebias marmoratus as a function of development, gender type and chemical exposure. Chem Biol Interact. 2008;174:118-25 pubmed publisher
    ..These findings indicate that the gonad of K. marmoratus has a robust antioxidant system. The gender-related differences in GSTM expression imply a differential sensitivity to EDCs in gender type. ..
  71. Maldonado E, Hubert N, Sagnes P, De Mérona B. Morphology-diet relationships in four killifishes (Teleostei, Cyprinodontidae, Orestias) from Lake Titicaca. J Fish Biol. 2009;74:502-20 pubmed publisher
    This study explores the relationship between morphology and diet in four Andean killifishes (Orestias) from Lake Titicaca that are known to differ in habitat use...
  72. Al Ghanbousi R, Ba Omar T, Victor R. Effect of deltamethrin on the gills of Aphanius dispar: a microscopic study. Tissue Cell. 2012;44:7-14 pubmed publisher
    ..All present results have been compared with those of previous studies on gill damage caused by various chemical substances. The impacts of the damage on the functioning of gills as a respiratory organ are discussed. ..
  73. Weinersmith K, Hanninen A, Sih A, McElreath R, Earley R. The relationship between handling time and cortisol release rates changes as a function of brain parasite densities in California killifish Fundulus parvipinnis. J Fish Biol. 2016;88:1125-42 pubmed publisher
    ..The relationship between handling time and cortisol release rates was negative for F. parvipinnis harbouring low or intermediate density infections, and became positive for fish harbouring high densities of EUHA. ..
  74. Sahm A, Bens M, Platzer M, Cellerino A. Parallel evolution of genes controlling mitonuclear balance in short-lived annual fishes. Aging Cell. 2017;16:488-496 pubmed publisher
    ..e., short-lived) and nonannual (i.e., longer-lived) African killifishes to identify a genomic substrate for evolution of annual life history (and reduced lifespan)...
  75. Kalogianni E, Kmentová N, Harris E, Zimmerman B, Giakoumi S, Chatzinikolaou Y, et al. Occurrence and effect of trematode metacercariae in two endangered killifishes from Greece. Parasitol Res. 2017;116:3007-3018 pubmed publisher
    ..Our findings are discussed in conjunction to fish conservation interventions, since parasites may contribute to the decline of endangered species. ..
  76. Krause J, Butlin R, Peuhkuri N, Pritchard V. The social organization of fish shoals: a test of the predictive power of laboratory experiments for the field. Biol Rev Camb Philos Soc. 2000;75:477-501 pubmed
  77. Tech C. Postzygotic incompatibilities between the pupfishes, Cyprinodon elegans and Cyprinodon variegatus: hybrid male sterility and sex ratio bias. J Evol Biol. 2006;19:1830-7 pubmed
    ..The results of this study provide insight on the evolution of reproductive isolating mechanisms, particularly the role of Haldane's rule and the 'faster-male' theory in taxa lacking well-differentiated sex chromosomes. ..
  78. Lotufo G. Whole-body and body-part-specific bioconcentration of explosive compounds in sheepshead minnows. Ecotoxicol Environ Saf. 2011;74:301-6 pubmed publisher
  79. Meller C, Meller R, Simon R, Culpepper K, Podrabsky J. Cell cycle arrest associated with anoxia-induced quiescence, anoxic preconditioning, and embryonic diapause in embryos of the annual killifish Austrofundulus limnaeus. J Comp Physiol B. 2012;182:909-20 pubmed
    ..limnaeus during embryonic diapause and in response to anoxia and builds a foundation for future research on the role of cell cycle arrest in supporting vertebrate dormancy. ..
  80. Brix K, Grosell M. Evaluation of pre- and post-zygotic mating barriers, hybrid fitness and phylogenetic relationship between Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi (Cyprinodontiformes, Teleostei). J Evol Biol. 2013;26:854-66 pubmed publisher
    ..Overall, the available data suggest that Cvh should be considered a separate species or at a minimum an evolutionarily significant unit. ..
  81. Kilian E, Avenant Oldewage A. Infestation and pathological alterations by Ergasilus sarsi (Copepoda) on the Tanganyika Killifish from Africa. J Aquat Anim Health. 2013;25:237-42 pubmed publisher
    ..Haemorrhage due to blood vessel compression was noted. This is the first record of E. sarsi from Tanganyika Killifish. This study is also the first to provide a description of the pathological alterations caused by E. sarsi. ..
  82. Petrino T, Greeley M, Selman K, Lin Y, Wallace R. Steroidogenesis in Fundulus heteroclitus. II. Production of 17 alpha-hydroxy-20 beta-dihydroprogesterone, testosterone, and 17 beta-estradiol by various components of the ovarian follicle. Gen Comp Endocrinol. 1989;76:230-40 pubmed
  83. Fournie J, Vogelbein W, Overstreet R, Hawkins W. Life cycle of Calyptospora funduli (Apicomplexa: Calyptosporidae). J Parasitol. 2000;86:501-5 pubmed
    ..funduli, that a developmental period of about 5 days in grass shrimp is necessary for sporozoites to become infective to killifishes, and that sporozoites do occur intracellularly in gut basal cells of the grass shrimp.
  84. Krause J, Hoare D, Croft D, Lawrence J, Ward A, Ruxton G, et al. Fish shoal composition: mechanisms and constraints. Proc Biol Sci. 2000;267:2011-7 pubmed
    ..This work has implications for studies on information transfer and reciprocal altruism within populations. ..
  85. Dube M, MacLatchy D. Identification and treatment of a waste stream at a bleached-kraft pulp mill that depresses a sex steroid in the mummichog (Fundulus heteroclitus). Environ Toxicol Chem. 2001;20:985-95 pubmed
    ..Results also confirmed that RO treatment removed the potential of the condensates to depress plasma testosterone in mummichog at environmentally relevant concentrations of final mill effluent (1%). ..
  86. Larkin P, Folmar L, Hemmer M, Poston A, Denslow N. Expression profiling of estrogenic compounds using a sheepshead minnow cDNA macroarray. EHP Toxicogenomics. 2003;111:29-36 pubmed
    ..We show that our estrogen-responsive cDNA macroarray can detect dose-dependent changes in gene expression patterns in fish treated with EE2. ..
  87. del Pilar Corena M, van den Hurk P, Zhong H, Brock C, Mowery R, Johnson J, et al. Degradation and effects of the potential mosquito larvicides methazolamide and acetazolamide in sheepshead minnow (Cyprinodon variegatus). Ecotoxicol Environ Saf. 2006;64:369-76 pubmed
    ..In the gills, MTZ concentrations were around 40 microg g(-1) and ACZ reached concentrations up to 80 microg g(-1). Liver concentrations were low for MTZ probably due to metabolism. ..
  88. Lauer L, McCarthy M, Mong J, Kane A. Sex differences in neuronal morphology in the killifish hypothalamus. Brain Res. 2006;1070:145-9 pubmed
    ..By contrast, no statistically significant difference between males and females was detected in spine densities in the rostral medulla. This finding supports the conclusion that hypothalamic sexual dimorphism is conserved in killifish. ..
  89. Valenzano D, Cellerino A. Resveratrol and the pharmacology of aging: a new vertebrate model to validate an old molecule. Cell Cycle. 2006;5:1027-32 pubmed
  90. Cripe G, Hemmer B, Goodman L, Vennari J. Development of a methodology for successful multigeneration life-cycle testing of the estuarine sheepshead minnow, Cyprinodon variegatus. Arch Environ Contam Toxicol. 2009;56:500-8 pubmed publisher
    ..Results of these experiments provide methods that are of particular interest in assessment of endocrine-disrupting chemicals that are known to affect reproduction. ..
  91. Adeyemi J, Klerks P. Salinity acclimation modulates copper toxicity in the sheepshead minnow, Cyprinodon variegatus. Environ Toxicol Chem. 2012;31:1573-8 pubmed publisher
    ..Copper exposure had generally insignificant effects for the 10.5 ppt and the 18.5 ppt acclimated fish. This study showed that even in euryhaline fish, salinity acclimation can have a drastic effect on Cu toxicity. ..
  92. Fournie J, Vogelbein W. Exocrine pancreatic neoplasms in the mummichog (Fundulus heteroclitus) from a creosote-contaminated site. Toxicol Pathol. 1994;22:237-47 pubmed