squalus acanthias

Summary

Summary: A species of shark in the family SQUALIDAE, used for its oil (SQUALENE) and as fish meal. It also figures heavily in biological research, especially with reference to its RECTAL GLAND in studies of WATER-ELECTROLYTE BALANCE.

Top Publications

  1. Tresguerres M, Katoh F, Fenton H, Jasinska E, Goss G. Regulation of branchial V-H(+)-ATPase, Na(+)/K(+)-ATPase and NHE2 in response to acid and base infusions in the Pacific spiny dogfish (Squalus acanthias). J Exp Biol. 2005;208:345-54 pubmed
    ..Western analysis in gill membranes from HCl-infused fish also revealed increased abundance of Na(+)/H(+) exchanger 2 (213+/-5%) and Na(+)/K(+)-ATPase (315+/-88%) compared to the control...
  2. Moriyama S, Oda M, Yamazaki T, Yamaguchi K, Amiya N, Takahashi A, et al. Gene structure and functional characterization of growth hormone in dogfish, Squalus acanthias. Zoolog Sci. 2008;25:604-13 pubmed publisher
    Dogfish (Squalus acanthias) growth hormone (GH) was identified by cDNA cloning and protein purification from the pituitary gland. Dogfish GH cDNA encoded a prehormone of 210 amino acids (aa)...
  3. Kajimura M, Walsh P, Mommsen T, Wood C. The dogfish shark (Squalus acanthias) increases both hepatic and extrahepatic ornithine urea cycle enzyme activities for nitrogen conservation after feeding. Physiol Biochem Zool. 2006;79:602-13 pubmed
    ..effect of feeding, and thus elevated nitrogen intake, on nitrogen metabolism in the Pacific spiny dogfish Squalus acanthias. We determined the activities of ornithine urea cycle (O-UC) and related enzymes in liver and nonhepatic ..
  4. Wood C, Kajimura M, Bucking C, Walsh P. Osmoregulation, ionoregulation and acid-base regulation by the gastrointestinal tract after feeding in the elasmobranch (Squalus acanthias). J Exp Biol. 2007;210:1335-49 pubmed
    ..Our results illustrate the complex integration of digestive and ionoregulatory function in the elasmobranch digestive tract, and marked differences from the teleost pattern...
  5. Smith L, Crouch K, Cao W, Muller M, Wu L, Steven J, et al. Characterization of the immunoglobulin repertoire of the spiny dogfish (Squalus acanthias). Dev Comp Immunol. 2012;36:665-79 pubmed publisher
    ..In this manuscript we characterize the immunoglobulins of the spiny dogfish (Squalus acanthias) at both the molecular and expressed protein levels...
  6. Veríssimo A, Grubbs D, McDowell J, Musick J, Portnoy D. Frequency of multiple paternity in the spiny dogfish Squalus acanthias in the western north Atlantic. J Hered. 2011;102:88-93 pubmed publisher
    ..In the squaloid shark Squalus acanthias, MP has been reported, but whether it is a common feature of the species' reproductive strategy is unknown...
  7. Parton A, Bayne C, Barnes D. Analysis and functional annotation of expressed sequence tags from in vitro cell lines of elasmobranchs: Spiny dogfish shark (Squalus acanthias) and little skate (Leucoraja erinacea). Comp Biochem Physiol Part D Genomics Proteomics. 2010;5:199-206 pubmed publisher
    ..Previously we developed cell lines from embryos of two elasmobranchs, Squalus acanthias the spiny dogfish shark (SAE line), and Leucoraja erinacea the little skate (LEE-1 line)...
  8. Springauf A, Grunder S. An acid-sensing ion channel from shark (Squalus acanthias) mediates transient and sustained responses to protons. J Physiol. 2010;588:809-20 pubmed publisher
    ..Our results show that the conservation of the amino acids crucial for proton gating can predict proton sensitivity of an ASIC and increase our understanding of the evolution of ASICs...
  9. Li R, Dooley H, Wang T, Secombes C, Bird S. Characterisation and expression analysis of B-cell activating factor (BAFF) in spiny dogfish (Squalus acanthias): cartilaginous fish BAFF has a unique extra exon that may impact receptor binding. Dev Comp Immunol. 2012;36:707-17 pubmed publisher
    ..A BAFF gene has been cloned from spiny dogfish (Squalus acanthias) and its expression studied...

More Information

Publications62

  1. Choe K, Edwards S, Claiborne J, Evans D. The putative mechanism of Na(+) absorption in euryhaline elasmobranchs exists in the gills of a stenohaline marine elasmobranch, Squalus acanthias. Comp Biochem Physiol A Mol Integr Physiol. 2007;146:155-62 pubmed
    ..NHE3 antibody was used to localize the exchanger in the gills of the stenohaline marine spiny dogfish shark (Squalus acanthias)...
  2. Walsh P, Kajimura M, Mommsen T, Wood C. Metabolic organization and effects of feeding on enzyme activities of the dogfish shark (Squalus acanthias) rectal gland. J Exp Biol. 2006;209:2929-38 pubmed
    ..metabolites and enzyme activities from several metabolic pathways in several tissues of the dogfish shark, Squalus acanthias, after starvation and at 6, 20, 30 and 48 h post-feeding...
  3. Eyckmans M, Lardon I, Wood C, De Boeck G. Physiological effects of waterborne lead exposure in spiny dogfish (Squalus acanthias). Aquat Toxicol. 2013;126:373-81 pubmed publisher
    To broaden our knowledge about the toxicity of metals in marine elasmobranchs, cannulated spiny dogfish (Squalus acanthias) were exposed to 20 ?M and 100 ?M lead (Pb)...
  4. Tresguerres M, Parks S, Katoh F, Goss G. Microtubule-dependent relocation of branchial V-H+-ATPase to the basolateral membrane in the Pacific spiny dogfish (Squalus acanthias): a role in base secretion. J Exp Biol. 2006;209:599-609 pubmed
    ..Our results strongly suggest that cellular relocation of V-H+-ATPase is necessary for enhanced HCO3- secretion across the gills of the Pacific dogfish...
  5. Wood C, Kajimura M, Mommsen T, Walsh P. Alkaline tide and nitrogen conservation after feeding in an elasmobranch (Squalus acanthias). J Exp Biol. 2005;208:2693-705 pubmed
  6. McClusky L. Stage and season effects on cell cycle and apoptotic activities of germ cells and Sertoli cells during spermatogenesis in the spiny dogfish (Squalus acanthias). Reproduction. 2005;129:89-102 pubmed
    To understand the processes involved in the spatial and temporal maturation of testicular cells in Squalus acanthias, we used standard morphometry, proliferating-cell nuclear antigen (PCNA) and terminal deoxynucleotidyl transferase-..
  7. Simard C, Daigle N, Bergeron M, Brunet G, Caron L, Noël M, et al. Characterization of a novel interaction between the secretory Na+-K+-Cl- cotransporter and the chaperone hsp90. J Biol Chem. 2004;279:48449-56 pubmed
    ..Further studies will be required to elucidate the functional relevance of this novel interaction...
  8. Wood C, Kajimura M, Mommsen T, Walsh P. Is the alkaline tide a signal to activate metabolic or ionoregulatory enzymes in the dogfish shark (Squalus acanthias)?. Physiol Biochem Zool. 2008;81:278-87 pubmed publisher
    ..We conclude that both the alkaline tide and salt loading/volume expansion act as signals to activate some but not all of the elevated metabolic pathways and ionoregulatory mechanisms needed during processing of a meal...
  9. Chana Munoz A, Jendroszek A, Sønnichsen M, Kristiansen R, Jensen J, Andreasen P, et al. Multi-tissue RNA-seq and transcriptome characterisation of the spiny dogfish shark (Squalus acanthias) provides a molecular tool for biological research and reveals new genes involved in osmoregulation. PLoS ONE. 2017;12:e0182756 pubmed publisher
    The spiny dogfish shark (Squalus acanthias) is one of the most commonly used cartilaginous fishes in biological research, especially in the fields of nitrogen metabolism, ion transporters and osmoregulation...
  10. Deck C, McKay S, Fiedler T, LeMoine C, Kajimura M, Nawata C, et al. Transcriptome responses in the rectal gland of fed and fasted spiny dogfish shark (Squalus acanthias) determined by suppression subtractive hybridization. Comp Biochem Physiol Part D Genomics Proteomics. 2013;8:334-43 pubmed publisher
    ..from rectal glands of fasted (7days post-feeding) and fed (6h and 22h post-feeding) spiny dogfish sharks (Squalus acanthias), and the libraries were subjected to suppression subtractive hybridization (SSH) analysis...
  11. McClusky L. Testicular degeneration during spermatogenesis in the blue shark, Prionace glauca: nonconformity with expression as seen in the diametric testes of other carcharhinids. J Morphol. 2011;272:938-48 pubmed publisher
    ..Because of the simple diametrical arrangement of cysts in maturational order, the testes of Squalus acanthias, Scyliorhinus canicula, and Prionace glauca are classified as the diametric shark testis type...
  12. Reiss K, Bonnan M. Ontogenetic scaling of caudal fin shape in Squalus acanthias (Chondrichthyes, Elasmobranchii): a geometric morphometric analysis with implications for caudal fin functional morphology. Anat Rec (Hoboken). 2010;293:1184-91 pubmed publisher
    ..We examined ontogenetic and sex-related shape changes in the caudal fins of 115 Squalus acanthias museum specimens, to test the hypothesis that significant shape changes in the caudal fin shape occur with ..
  13. Babavali M, Esmann M, Fedosova N, Marsh D. Urea-induced unfolding of Na,K-ATPase as evaluated by electron paramagnetic resonance spectroscopy. Biochemistry. 2009;48:9022-30 pubmed publisher
    ..Susceptibility of the latter could arise from the nonhomologous regions in the cytoplasmic domain...
  14. McCall A, Kraft S, Edelhauser H, Kidder G, Lundquist R, Bradshaw H, et al. Mechanisms of corneal tissue cross-linking in response to treatment with topical riboflavin and long-wavelength ultraviolet radiation (UVA). Invest Ophthalmol Vis Sci. 2010;51:129-38 pubmed publisher
    ..RFUVA treatment retards the progression of keratoconus, perhaps by cross-linking of collagen molecules, but exact molecular mechanisms remain unknown. Research described here tested possible chemical mechanisms of cross-linking...
  15. Janowski E, Day R, Kraev A, Roder J, Cleemann L, Morad M. beta-adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells. Am J Physiol Heart Circ Physiol. 2009;296:H1994-2006 pubmed publisher
    ..Here we investigated the bimodal, cAMP-dependent regulation of spiny dogfish shark (Squalus acanthias) cardiac NCX, exploring the effects of molecular structure, host cell environment, and ionic milieu...
  16. McClusky L. Stage-dependency of apoptosis and the blood-testis barrier in the dogfish shark (Squalus acanthias): cadmium-induced changes as assessed by vital fluorescence techniques. Cell Tissue Res. 2006;325:541-53 pubmed
    ..Sharks such as Squalus acanthias provide a suitable model for studying aspects of vertebrate spermatogenosis because of their unique features:..
  17. Treberg J, Crockett E, Driedzic W. Activation of liver carnitine palmitoyltransferase-1 and mitochondrial acetoacetyl-CoA thiolase is associated with elevated ketone body levels in the elasmobranch Squalus acanthias. Physiol Biochem Zool. 2006;79:899-908 pubmed
    ..Compared to specimens sampled within 2 d of capture (recently captured), spiny dogfish Squalus acanthias that were held for 16-33 d without apparent feeding displayed a 4...
  18. Mahmmoud Y, Vorum H, Cornelius F. Interaction of FXYD10 (PLMS) with Na,K-ATPase from shark rectal glands. Close proximity of Cys74 of FXYD10 to Cys254 in the a domain of the alpha-subunit revealed by intermolecular thiol cross-linking. J Biol Chem. 2005;280:27776-82 pubmed
    ..Thus, regulation of Na,K-ATPase by FXYD10 occurs in part via cytoplasmic interaction of FXYD10 with the A domain of the shark alpha-subunit...
  19. Claiborne J, Choe K, Morrison Shetlar A, Weakley J, Havird J, Freiji A, et al. Molecular detection and immunological localization of gill Na+/H+ exchanger in the dogfish (Squalus acanthias). Am J Physiol Regul Integr Comp Physiol. 2008;294:R1092-102 pubmed
    The dogfish (Squalus acanthias) can make rapid adjustments to gill acid-base transfers to compensate for internal acidosis/alkalosis...
  20. Huysseune A, Witten P. An evolutionary view on tooth development and replacement in wild Atlantic salmon (Salmo salar L.). Evol Dev. 2008;10:6-14 pubmed publisher
    ..of tooth replacement in Atlantic salmon displays several characters similar to those observed in the shark Squalus acanthias. To interpret similarities in tooth replacement between Atlantic salmon and chondrichthyans as a case of ..
  21. De Boeck G, Hattink J, Franklin N, Bucking C, Wood S, Walsh P, et al. Copper toxicity in the spiny dogfish (Squalus acanthias): urea loss contributes to the osmoregulatory disturbance. Aquat Toxicol. 2007;84:133-41 pubmed
    Previous research showed that the spiny dogfish, Squalus acanthias, is much more sensitive to silver exposure than typical marine teleosts...
  22. Reinick C, Liang L, Angleson J, Dores R. Functional expression of Squalus acanthias melanocortin-5 receptor in CHO cells: ligand selectivity and interaction with MRAP. Eur J Pharmacol. 2012;680:1-7 pubmed publisher
    The melanocortin-5 receptor (MC(5)) of the dogfish Squalus acanthias (SacMC(5) receptor) can be functionally expressed in CHO cells in the absence of the co-expression of an exogenous MRAP cDNA...
  23. Crouch K, Smith L, Williams R, Cao W, Lee M, Jensen A, et al. Humoral immune response of the small-spotted catshark, Scyliorhinus canicula. Fish Shellfish Immunol. 2013;34:1158-69 pubmed publisher
    ..immune function in small-spotted catshark (Scyliorhinus canicula) with that described for spiny dogfish (Squalus acanthias), another member of the Squalomorphi superorder, and nurse shark, the model for humoral immunity in ..
  24. Fellner S, Parker L. Endothelin-1, superoxide and adeninediphosphate ribose cyclase in shark vascular smooth muscle. J Exp Biol. 2005;208:1045-52 pubmed
    In vascular smooth muscle (VSM) of Squalus acanthias, endothelin-1 (ET-1) signals via the ET(B) receptor...
  25. Poulsen H, Khandelia H, Morth J, Bublitz M, Mouritsen O, Egebjerg J, et al. Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase. Nature. 2010;467:99-102 pubmed publisher
    ..A similar ion regulation is likely to apply to the H(+)/K(+)-ATPase and the Ca(2+)-ATPase...
  26. Pellegrino D, Tota B, Randall D. Adenosine/nitric oxide crosstalk in the branchial circulation of Squalus acanthias and Anguilla anguilla. Comp Biochem Physiol A Mol Integr Physiol. 2005;142:198-204 pubmed
    ..the actions of AD in fish, we have analysed this question in the branchial vasculature of the elasmobranch Squalus acanthias and the teleost Anguilla anguilla using an isolated perfused head and a branchial basket preparation, ..
  27. Cornelius F, Kanai R, Toyoshima C. A structural view on the functional importance of the sugar moiety and steroid hydroxyls of cardiotonic steroids in binding to Na,K-ATPase. J Biol Chem. 2013;288:6602-16 pubmed publisher
    ..The results are discussed with reference to the recent crystal structures of Na,K-ATPase in the unbound and ouabain-bound states...
  28. Li R, Wang T, Bird S, Zou J, Dooley H, Secombes C. B cell receptor accessory molecule CD79?: characterisation and expression analysis in a cartilaginous fish, the spiny dogfish (Squalus acanthias). Fish Shellfish Immunol. 2013;34:1404-15 pubmed publisher
    ..In this study the spiny dogfish (Squalus acanthias) CD79? (SaCD79?) is described and its expression studied under constitutive and stimulated conditions...
  29. Shuttleworth T, Thompson J, Munger R, Wood C. A critical analysis of carbonic anhydrase function, respiratory gas exchange, and the acid-base control of secretion in the rectal gland of Squalus acanthias. J Exp Biol. 2006;209:4701-16 pubmed
  30. Barnes D. Cell and molecular biology of the spiny dogfish Squalus acanthias and little skate Leucoraja erinacea: insights from in vitro cultured cells. J Fish Biol. 2012;80:2089-111 pubmed publisher
    Two of the most commonly used elasmobranch experimental model species are the spiny dogfish Squalus acanthias and the little skate Leucoraja erinacea...
  31. Stolz M, Lewitzki E, Bergbauer R, Mäntele W, Grell E, Barth A. Structural changes in the catalytic cycle of the Na+,K+-ATPase studied by infrared spectroscopy. Biophys J. 2009;96:3433-42 pubmed publisher
    ..A negative band at 1730 cm(-1) is in line with the presence of a protonated Asp or Glu residue that coordinates Na(+) in E1Na(3)(+). Infrared signals were also detected in the absorption regions of ionized carboxyl groups...
  32. Sandblom E, Cox G, Perry S, Farrell A. The role of venous capacitance, circulating catecholamines, and heart rate in the hemodynamic response to increased temperature and hypoxia in the dogfish. Am J Physiol Regul Integr Comp Physiol. 2009;296:R1547-56 pubmed publisher
    ..9 kPa) and severe (2.5 kPa) hypoxia in the dogfish (Squalus acanthias). Normoxic dogfish at 10 degrees C had a P(cv) between -0.08 and -0...
  33. St Gelais A, Costa Pierce B. Mercury concentrations in Northwest Atlantic winter-caught, male spiny dogfish (Squalus acanthias): A geographic mercury comparison and risk-reward framework for human consumption. Mar Pollut Bull. 2016;102:199-205 pubmed publisher
    Mercury (Hg) contamination testing was conducted on winter-caught male spiny dogfish (Squalus acanthias) in southern New England and results compared to available data on Hg concentrations for this species...
  34. Liu J, Zabetakis D, Brown J, Anderson G, Goldman E. Thermal stability and refolding capability of shark derived single domain antibodies. Mol Immunol. 2014;59:194-9 pubmed publisher
    ..This work demonstrated that although shark sdAb can possess high melting temperatures and refolding ability, no clear advantage over sdAb derived from camelids in terms of thermostability and renaturation was obtained. ..
  35. McClusky L. Coordination of spermatogenic processes in the testis: lessons from cystic spermatogenesis. Cell Tissue Res. 2012;349:703-15 pubmed
  36. McClusky L. Fetal bovine serum simultaneously stimulates apoptosis and DNA synthesis in premeiotic stages of spermatogenesis in spiny dogfish (Squalus acanthias) in vitro: modulation by androgen and spermatogenic activity status. Apoptosis. 2008;13:649-58 pubmed publisher
    ..Results are discussed in the context of the alternating germ-Sertoli cell population kinetics of early-stage spermatogonial cysts in Squalus acanthias's protracted testicular cycle.
  37. McKenzie R, Motta P, Rohr J. Comparative squamation of the lateral line canal pores in sharks. J Fish Biol. 2014;84:1300-11 pubmed publisher
    ..pelagic shortfin mako shark Isurus oxyrinchus and the slow-swimming epi-benthic spiny dogfish shark Squalus acanthias was examined. Pore scale morphology and pore coverage were qualitatively analysed and compared...
  38. Kobayashi H, Parton A, Czechanski A, Durkin C, Kong C, Barnes D. Multidrug resistance-associated protein 3 (Mrp3/Abcc3/Moat-D) is expressed in the SAE Squalus acanthias shark embryo-derived cell line. Zebrafish. 2007;4:261-75 pubmed publisher
    ..We have derived from the embryo of Squalus acanthias, the spiny dogfish shark, the S. acanthias embryo (SAE) mesenchymal stem cell line...
  39. McClusky L. Cadmium accumulation and binding characteristics in intact Sertoli/germ cell units, and associated effects on stage-specific functions in vitro: insights from a shark testis model. J Appl Toxicol. 2008;28:112-21 pubmed
    ..These findings demonstrate that this model has utility for use in screening assays of environmental toxicants...
  40. Sandblom E, Axelsson M, Farrell A. Central venous pressure and mean circulatory filling pressure in the dogfish Squalus acanthias: adrenergic control and role of the pericardium. Am J Physiol Regul Integr Comp Physiol. 2006;291:R1465-73 pubmed
    ..Venous capacitance was estimated in the dogfish Squalus acanthias by measuring the mean circulatory filling pressure (MCFP) during transient occlusion of cardiac outflow...
  41. Ikonomou M, Fernandez M, Hickman Z. Spatio-temporal and species-specific variation in PBDE levels/patterns in British Columbia's coastal waters. Environ Pollut. 2006;140:355-63 pubmed
    ..muscle tissues of Dungeness crab (Cancer magister), English sole (Pleuronectes vetulus) and spiny dogfish (Squalus acanthias)...
  42. Matthews G, Gould R, Vardimon L. A single glutamine synthetase gene produces tissue-specific subcellular localization by alternative splicing. FEBS Lett. 2005;579:5527-34 pubmed
    ..Here we show that in the ureosmotic elasmobranch, Squalus acanthias (spiny dogfish), two different GS transcripts are generated by tissue-specific alternative splicing...
  43. Reum J. Lipid correction model of carbon stable isotopes for a cosmopolitan predator, spiny dogfish Squalus acanthias. J Fish Biol. 2011;79:2060-6 pubmed publisher
    Three lipid correction models were evaluated for liver and white dorsal muscle from Squalus acanthias. For muscle, all three models performed well, based on the Akaike Information Criterion value corrected for small sample sizes (AIC(c) )..
  44. Endo T, Hisamichi Y, Kimura O, Ogasawara H, Ohta C, Koga N, et al. Levels of mercury in muscle and liver of star-spotted dogfish (Mustelus manazo) from the northern region of Japan: a comparison with spiny dogfish (Squalus acanthias). Arch Environ Contam Toxicol. 2013;64:467-74 pubmed publisher
    ..Mustelus manazo) caught off the northern region of Japan and compared them with those of spiny dogfish (Squalus acanthias) caught in the same region...
  45. Fellner S, Parker L. Endothelin B receptor Ca2+ signaling in shark vascular smooth muscle: participation of inositol trisphosphate and ryanodine receptors. J Exp Biol. 2004;207:3411-7 pubmed
    ..measured cytosolic Ca(2+) concentration ([Ca(2+)](i)) in fura-2-loaded VSM of anterior mesenteric artery of Squalus acanthias and show that the ET(B)R agonists IRL 1620 and sarafotoxin S6c (SRX) increase [Ca(2+)](i) in VSM to the same ..
  46. Liew H, De Boeck G, Wood C. An in vitro study of urea, water, ion and CO2/HCO3- transport in the gastrointestinal tract of the dogfish shark (Squalus acanthias): the influence of feeding. J Exp Biol. 2013;216:2063-72 pubmed publisher
    ..Phloretin (0.25 mmol l(-1), applied mucosally) completely blocked the increases in intestinal urea absorption and CO2/HCO3(-) secretion caused by feeding, but had no effect on Na(+), Cl(-) or water absorption...
  47. Greger R, Thiele I, Warth R, Bleich M. Does stimulation of NaCl secretion in in vitro perfused rectal gland tubules of Squalus acanthias increase membrane capacitance?. Pflugers Arch. 1998;436:538-44 pubmed
    NaCl secretion in rectal gland tubules (RGT) of Squalus acanthias requires the activation of Cl– channels in the luminal membrane. The RGT and its mechanism of activation are an early evolutionary paradigm of exocrine secretion...
  48. Maia A, Wilga C. Anatomy and muscle activity of the dorsal fins in bamboo sharks and spiny dogfish during turning maneuvers. J Morphol. 2013;274:1288-98 pubmed publisher
    ..Thus, dogfish sharks passively stiffen the dorsal fin structurally and functionally, while bamboo sharks have more flexible dorsal fins, which result from a steady swimming trade off...
  49. Anderson W, Nawata C, Wood C, Piercey Normore M, Weihrauch D. Body fluid osmolytes and urea and ammonia flux in the colon of two chondrichthyan fishes, the ratfish, Hydrolagus colliei, and spiny dogfish, Squalus acanthias. Comp Biochem Physiol A Mol Integr Physiol. 2012;161:27-35 pubmed publisher
    ..in two species of chondrichthyans, the ratfish, Hydrolagus colliei (a holocephalan) and the spiny dogfish, Squalus acanthias (an elasmobranch)...
  50. Salaneck E, Larson E, Larsson T, Larhammar D. Effects of a teleost tetraploidization on neuropeptide Y receptor gene repertoire in ray-finned fishes. Ann N Y Acad Sci. 2005;1040:457-9 pubmed
    ..These dramatic alterations of the teleost receptor repertoire may be related to the tetraploidization in a teleost ancestor...
  51. Warth R, Bleich M, Thiele I, Lang F, Greger R. Regulation of the Na+2Cl–K+ cotransporter in in vitro perfused rectal gland tubules of Squalus acanthias. Pflugers Arch. 1998;436:521-8 pubmed
    ..of the furosemide-inhibitable Na+2Cl–K+ cotransporter in in vitroperfused rectal gland tubules (RGT) of Squalus acanthias. Addition of NH4 + to the bath (20 mmol/l) led to an initial alkalinization, corresponding to NH3 uptake...
  52. Reichel V, Miller D, Fricker G. Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus. Am J Physiol Regul Integr Comp Physiol. 2008;295:R1311-9 pubmed publisher
    ..in lateral choroid plexus (CP) isolated from rat and an evolutionarily ancient vertebrate, dogfish shark (Squalus acanthias)...
  53. Althoff T, Hentschel H, Luig J, Schütz H, Kasch M, Kinne R. Na(+)-D-glucose cotransporter in the kidney of Squalus acanthias: molecular identification and intrarenal distribution. Am J Physiol Regul Integr Comp Physiol. 2006;290:R1094-104 pubmed
    ..mammalian Na(+)-d-glucose cotransporters (SGLT), a cDNA was cloned from the kidney of spiny dogfish shark (Squalus acanthias)...