entamoeba

Summary

Summary: A genus of ameboid protozoa characterized by the presence of beaded chromatin on the inner surface of the nuclear membrane. Its organisms are parasitic in invertebrates and vertebrates, including humans.

Top Publications

  1. Lebbad M, Svard S. PCR differentiation of Entamoeba histolytica and Entamoeba dispar from patients with amoeba infection initially diagnosed by microscopy. Scand J Infect Dis. 2005;37:680-5 pubmed
    ..The true number of patients with Entamoeba histolytica infection is unknown as diagnosis mainly relies on cyst detection by microscopy...
  2. Lorenzi H, Thiagarajan M, Haas B, Wortman J, Hall N, Caler E. Genome wide survey, discovery and evolution of repetitive elements in three Entamoeba species. BMC Genomics. 2008;9:595 pubmed publisher
    ..During the assembly and annotation of three highly repetitive amoeba genomes, Entamoeba histolytica, Entamoeba dispar, and Entamoeba invadens, we performed comparative sequence analysis to identify ..
  3. Aksoy U, Sahin S, Ozkoc S, Ergor G. The effect of electromagnetic waves on the growth of Entamoeba histolytica and Entamoeba dispar. Saudi Med J. 2005;26:1388-90 pubmed
    ..of electromagnetic radiation of a digital Global System for Mobile Communication mobile telephone (900 MHz) on Entamoeba histolytica (E. histolytica) and Entamoeba dispar (E...
  4. Dey T, Basu R, Ghosh S. Entamoeba invadens: cloning and molecular characterization of chitinases. Exp Parasitol. 2009;123:244-9 pubmed publisher
    b>Entamoeba histolytica, the causative agent of amebiasis infects through its cyst form and this transmission may be blocked using encystation specific protein as drug target...
  5. Makioka A, Kumagai M, Ohtomo H, Kobayashi S, Takeuchi T. Entamoeba invadens: enhancement of excystation and metacystic development by cytochalasin D. Exp Parasitol. 2001;98:145-51 pubmed
    ..cytochalasin D, latrunculin A, and jasplakinolide, on the excystation and metacystic development in vitro of Entamoeba invadens were examined by transfer of the cysts to growth medium with the drugs...
  6. Lauwaet T, Oliveira M, De Bruyne G, Bruchhaus I, Duchene M, Mareel M, et al. Entamoeba histolytica trophozoites transfer lipophosphopeptidoglycans to enteric cell layers. Int J Parasitol. 2004;34:549-56 pubmed
    ..We were interested in such transfer from the Entamoeba surface to enterocytes following adhesion of trophozoites...
  7. Tachibana H, Yanagi T, Akatsuka A, Kobayashi S, Kanbara H, Tsutsumi V. Isolation and characterization of a potentially virulent species Entamoeba nuttalli from captive Japanese macaques. Parasitology. 2009;136:1169-77 pubmed publisher
    We have recently proposed revival of the name Entamoeba nuttalli Castellani, 1908 for a virulent amoeba (P19-061405 strain) isolated from a rhesus monkey (Macaca mulatta) and located phylogenetically between E. histolytica and E. dispar...
  8. Tibayrenc M, Kjellberg F, Ayala F. A clonal theory of parasitic protozoa: the population structures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and their medical and taxonomical consequences. Proc Natl Acad Sci U S A. 1990;87:2414-8 pubmed
    ..Uniparental reproduction renders unsatisfactory Linnean taxonomy; this needs to be supplemented by the "natural clone" as an additional taxonomic unit, which is best defined by means of genetic markers...
  9. Song J, Xu Q, Olsen R, Loomis W, Shaulsky G, Kuspa A, et al. Comparing the Dictyostelium and Entamoeba genomes reveals an ancient split in the Conosa lineage. PLoS Comput Biol. 2005;1:e71 pubmed
    ..The social amoeba Dictyostelium discoideum and amitochondriate pathogen Entamoeba histolytica are the first Amoebozoa with genomes completely sequenced...

More Information

Publications142 found, 100 shown here

  1. Davis P, Chen M, Zhang X, Clark C, Townsend R, Stanley S. Proteomic comparison of Entamoeba histolytica and Entamoeba dispar and the role of E. histolytica alcohol dehydrogenase 3 in virulence. PLoS Negl Trop Dis. 2009;3:e415 pubmed publisher
    The protozoan intestinal parasite Entamoeba histolytica infects millions of people worldwide and is capable of causing amebic dysentery and amebic liver abscess...
  2. Nakada Tsukui K, Saito Nakano Y, Husain A, Nozaki T. Conservation and function of Rab small GTPases in Entamoeba: annotation of E. invadens Rab and its use for the understanding of Entamoeba biology. Exp Parasitol. 2010;126:337-47 pubmed publisher
    b>Entamoeba invadens is a reptilian enteric protozoan parasite closely related to the human pathogen Entamoeba histolytica and a good model organism of encystation...
  3. Blessmann J, Buss H, Nu P, Dinh B, Ngo Q, Van A, et al. Real-time PCR for detection and differentiation of Entamoeba histolytica and Entamoeba dispar in fecal samples. J Clin Microbiol. 2002;40:4413-7 pubmed
    ..sensitive and specific detection and differentiation of the two closely related intestinal protozoan parasites Entamoeba histolytica and Entamoeba dispar directly from human feces...
  4. Srivastava S, Bhattacharya S, Paul J. Species- and strain-specific probes derived from repetitive DNA for distinguishing Entamoeba histolytica and Entamoeba dispar. Exp Parasitol. 2005;110:303-8 pubmed
    b>Entamoeba histolytica and Entamoeba dispar are two morphologically indistinguishable species that are found in the human gut. Of the two, E. histolytica is considered to be pathogenic while E. dispar is nonpathogenic...
  5. Suzuki J, Kobayashi S, Murata R, Tajima H, Hashizaki F, Yanagawa Y, et al. A survey of amoebic infections and differentiation of an Entamoeba histolytica-like variant (JSK2004) in nonhuman primates by a multiplex polymerase chain reaction. J Zoo Wildl Med. 2008;39:370-9 pubmed
    A pathogenic Entamoeba histolytica-like variant (JSK2004 strain) with genetic variations and a novel isoenzyme pattern isolated from a De Brazza's guenon in a Tokyo zoo in Japan has previously been documented...
  6. Chavez Munguia B, Martinez Palomo A. High-resolution electron microscopical study of cyst walls of Entamoeba spp. J Eukaryot Microbiol. 2011;58:480-6 pubmed publisher
    ..Recent studies on the biology of the cyst walls of Entamoeba histolytica and Entamoeba invadens have considerably advanced knowledge on the cellular processes involved in ..
  7. Ramos F, Garcia G, Valadez A, Moran P, Gonzalez E, Gomez A, et al. E. dispar strain: analysis of polymorphism as a tool for study of geographic distribution. Mol Biochem Parasitol. 2005;141:175-7 pubmed
    ..However both communities share 4 patterns. This finding suggests the presence of strains with different geographic mobility. ..
  8. Mukherjee C, Clark C, Lohia A. Entamoeba shows reversible variation in ploidy under different growth conditions and between life cycle phases. PLoS Negl Trop Dis. 2008;2:e281 pubmed publisher
    Under axenic growth conditions, trophozoites of Entamoeba histolytica contain heterogenous amounts of DNA due to the presence of both multiple nuclei and different amounts of DNA in individual nuclei...
  9. Rivera W, Tachibana H, Kanbara H. Application of the polymerase chain reaction (PCR) in the epidemiology of Entamoeba histolytica and Entamoeba dispar infections. Tokai J Exp Clin Med. 1998;23:413-5 pubmed
    ..we briefly summarize the latest information on the polymerase chain reaction (PCR) as an epidemiologic tool for Entamoeba histolytica and Entamoeba dispar infections...
  10. Tachibana H, Cheng X, Kobayashi S, Matsubayashi N, Gotoh S, Matsubayashi K. High prevalence of infection with Entamoeba dispar, but not E. histolytica, in captive macaques. Parasitol Res. 2001;87:14-7 pubmed
    ..rates as based on the presence of cysts in the stool following formalin-ether sedimentation were as follows: Entamoeba histolytica/E. dispar, 53%; E. coli, 34%; E...
  11. Chavez Munguia B, Cristóbal Ramos A, Gonzalez Robles A, Tsutsumi V, Martinez Palomo A. Ultrastructural study of Entamoeba invadens encystation and excystation. J Submicrosc Cytol Pathol. 2003;35:235-43 pubmed
    In the life cycle of Entamoeba species, the cyst and all the processes associated to it have been poorly studied...
  12. Stensvold C, Lebbad M, Victory E, Verweij J, Tannich E, Alfellani M, et al. Increased sampling reveals novel lineages of Entamoeba: consequences of genetic diversity and host specificity for taxonomy and molecular detection. Protist. 2011;162:525-41 pubmed publisher
    To expand the representation for phylogenetic analysis, ten additional complete Entamoeba small-subunit rRNA gene sequences were obtained from humans, non-human primates, cattle and a tortoise...
  13. Das S, Van Dellen K, Bulik D, Magnelli P, Cui J, Head J, et al. The cyst wall of Entamoeba invadens contains chitosan (deacetylated chitin). Mol Biochem Parasitol. 2006;148:86-92 pubmed publisher
    The cyst wall of Entamoeba invadens (Ei), a model for the human pathogen Entamoeba histolytica, contains chitin, which is a homopolymer of beta-1, 4-linked N-acetyl-glucosamine (GlcNAc)...
  14. Verweij J, Polderman A, Clark C. Genetic Variation among Human Isolates of Uninucleated Cyst-Producing Entamoeba Species. J Clin Microbiol. 2001;39:1644-6 pubmed
    Twelve human infections with Entamoeba spp. producing uninucleated cysts were studied. DNA was extracted from infected feces and used to amplify part of the ameba small-subunit rRNA gene...
  15. Ebert F, Bachmann A, Nakada Tsukui K, Hennings I, Drescher B, Nozaki T, et al. An Entamoeba cysteine peptidase specifically expressed during encystation. Parasitol Int. 2008;57:521-4 pubmed publisher
    Protozoan parasites of the genus Entamoeba possess a considerable number of cysteine peptidases (CPs), the function of most of these molecules for amoeba biology needs to be established...
  16. Moran P, Gomez A, Valadez A, Garcia G, Ramos F, Gonzalez E, et al. Periodicity and patterns of Entamoeba histolytica and E. dispar infection in HIV+/AIDS patients in Mexico. Ann Trop Med Parasitol. 2009;103:307-15 pubmed publisher
    In a 12-month longitudinal study, a cohort of Mexican HIV+/AIDS patients was checked several times for Entamoeba infection, with the parasites identified, as E. histolytica or E. dispar, using PCR...
  17. Ngui R, Angal L, Fakhrurrazi S, Lian Y, Ling L, Ibrahim J, et al. Differentiating Entamoeba histolytica, Entamoeba dispar and Entamoeba moshkovskii using nested polymerase chain reaction (PCR) in rural communities in Malaysia. Parasit Vectors. 2012;5:187 pubmed
    In this study, a total of 426 human faecal samples were examined for the presence of Entamoeba histolytica, Entamoeba dispar, Entamoeba moshkovskii infection via a combination of microscopic examination and nested polymerase chain ..
  18. Jackson T. Entamoeba histolytica and Entamoeba dispar are distinct species; clinical, epidemiological and serological evidence. Int J Parasitol. 1998;28:181-6 pubmed
    The name of the causative organism of invasive amoebiasis, Entamoeba histolytica, was first introduced in 1903, even though this intestinal amoeba had been recognised since 1875...
  19. Wilihoeft U, Campos Góngora E, Touzni S, Bruchhaus I, Tannich E. Introns of Entamoeba histolytica and Entamoeba dispar. Protist. 2001;152:149-56 pubmed
    The genome of Entamoeba histolytica is considered to possess very few intervening sequences (introns), as only 5 intron-containing genes from this protozoan parasite have been reported so far...
  20. Galván Moroyoqui J, Del Carmen Domínguez Robles M, Franco E, Meza I. The interplay between Entamoeba and enteropathogenic bacteria modulates epithelial cell damage. PLoS Negl Trop Dis. 2008;2:e266 pubmed publisher
    Mixed intestinal infections with Entamoeba histolytica, Entamoeba dispar and bacteria with exacerbated manifestations of disease are common in regions where amoebiasis is endemic...
  21. de la Vega H, Specht C, Semino C, Robbins P, Eichinger D, Caplivski D, et al. Cloning and expression of chitinases of Entamoebae. Mol Biochem Parasitol. 1997;85:139-47 pubmed
    b>Entamoeba histolytica (Eh) and Entamoeba dispar (Ed) are protozoan parasites that infect hundreds of millions of persons. In the colonic lumen, amebae form chitin-walled cysts, the infectious stage of the parasite...
  22. Frederick J, Eichinger D. Entamoeba invadens contains the components of a classical adrenergic signaling system. Mol Biochem Parasitol. 2004;137:339-43 pubmed
    ..Epi) was previously found to bypass the need for galactose ligands during early steps in the initiation of Entamoeba encystment...
  23. Khairnar K, Parija S, Palaniappan R. Diagnosis of intestinal amoebiasis by using nested polymerase chain reaction-restriction fragment length polymorphism assay. J Gastroenterol. 2007;42:631-40 pubmed
    Microscopy is unreliable to distinguish the pathogenic Entamoeba histolytica from the nonpathogenic Entamoeba dispar or Entamoeba moshkovskii in stool specimens.
  24. Liu G, Chen J, Wen W, Chen W, Lin L, Hong H. [Experimental study on the pathogenesis of Entamoeba gingivalis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001;19:229-32 pubmed
    To study the pathogenesis of Entamoeba gingivalis (E. g.) and its relation to periodontal diseases. Rats were treated with immuno-inhibitor for one week and the neck of incisor teeth of the rats was bound with steel wire...
  25. Wang Z, Vora G, Stenger D. Detection and genotyping of Entamoeba histolytica, Entamoeba dispar, Giardia lamblia, and Cryptosporidium parvum by oligonucleotide microarray. J Clin Microbiol. 2004;42:3262-71 pubmed
    b>Entamoeba histolytica, Giardia lamblia, and Cryptosporidium parvum are the most frequently identified protozoan parasites causing waterborne disease outbreaks...
  26. Santos F, Gonçalves M, Soares N. Validation and utilization of PCR for differential diagnosis and prevalence determination of Entamoeba histolytica/Entamoeba dispar in Salvador City, Brazil. Braz J Infect Dis. 2011;15:119-25 pubmed
    Amoebiasis is an infection caused by Entamoeba histolytica and is a potential health risk in countries in which health barriers are inappropriate. Since the discovery of Entamoeba dispar, the prevalence of amoebiasis has been modified...
  27. Rivera W, Yason J, Adao D. Entamoeba histolytica and E. dispar infections in captive macaques (Macaca fascicularis) in the Philippines. Primates. 2010;51:69-74 pubmed publisher
    b>Entamoeba histolytica is a protozoan parasite that infects man and animals. This parasite has a global distribution and the disease it causes is usually characterized by diarrhea...
  28. Makiuchi T, Mi ichi F, Nakada Tsukui K, Nozaki T. Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport. Sci Rep. 2013;3:1129 pubmed publisher
    ..In agreement with the concept of reductive evolution, mitosomes of Entamoeba histolytica lack most of the components of the TOM (translocase of the outer mitochondrial membrane) complex, ..
  29. Mirelman D, Nuchamowitz Y, Böhm Gloning B, Walderich B. A homologue of the cysteine proteinase gene (ACP1 or Eh-CPp3) of pathogenic Entamoeba histolytica is present in non-pathogenic E. dispar strains. Mol Biochem Parasitol. 1996;78:47-54 pubmed
    ..three cysteine proteinase genes, ACP1 (or CP 3), has been reported to be missing in non-pathogenic strains of Entamoeba histolytica (or Entamoeba dispar as recently labeled)...
  30. Richter B, Kübber Heiss A, Weissenbock H, Schmidt P. Detection of Cryptosporidium spp., Entamoeba spp. and Monocercomonas spp. in the gastrointestinal tract of snakes by in-situ hybridization. J Comp Pathol. 2008;138:63-71 pubmed publisher
    ..b>Entamoeba spp., Entamoeba invadens and Monocercomonas spp...
  31. Kikuta N, Yamamoto A, Goto N. Detection and identification of Entamoeba gingivalis by specific amplification of rRNA gene. Can J Microbiol. 1996;42:1248-51 pubmed
    ..nucleotide sequence of the gene encoding the small subunit ribosomal RNA (SrRNA) of the oral protozoan parasite Entamoeba gingivalis. The primers amplified a 1...
  32. Sharp S, Suarez C, Duran Y, Poppiti R. Evaluation of the Triage Micro Parasite Panel for detection of Giardia lamblia, Entamoeba histolytica/Entamoeba dispar, and Cryptosporidium parvum in patient stool specimens. J Clin Microbiol. 2001;39:332-4 pubmed
    ..Seven specimens were positive for Giardia lamblia, four were positive for Entamoeba histolytica/E. dispar, and three were positive for Cryptosporidium parvum as determined by both methods...
  33. Ganguly A, Lohia A. The cell cycle of Entamoeba invadens during vegetative growth and differentiation. Mol Biochem Parasitol. 2001;112:277-85 pubmed
    The cell division cycle of Entamoeba invadens was studied during vegetative growth of trophozoites and during their differentiation into cysts...
  34. Gonçalves A, Viana J, Pires E, Boia M, Coura J, Silva E. The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures. Rev Inst Med Trop Sao Paulo. 2007;49:201-2 pubmed
    In regions with high prevalence, Blastocystis hominis is frequently found in association with Entamoeba histolytica/E. dispar in xenic cultures...
  35. Sharma R, Bagchi A, Bhattacharya A, Bhattacharya S. Characterization of a retrotransposon-like element from Entamoeba histolytica. Mol Biochem Parasitol. 2001;116:45-53 pubmed
    The protozoan parasite Entamoeba histolytica is the causative agent of amoebiasis. The genome organization of this organism is not well understood. We had earlier reported the presence of a multicopy sequence, HMc, in E. histolytica...
  36. Kojimoto A, Uchida K, Horii Y, Okumura S, Yamaguch R, Tateyama S. Amebiasis in four ball pythons, Python reginus. J Vet Med Sci. 2001;63:1365-8 pubmed
    ..Based on the pathological findings, these snakes were infested with a member of Entamoeba sp., presumably with infection by Entamoeba invadens, the most prevalent type of reptilian amoebae.
  37. Visser L, Verweij J, Van Esbroeck M, Edeling W, Clerinx J, Polderman A. Diagnostic methods for differentiation of Entamoeba histolytica and Entamoeba dispar in carriers: performance and clinical implications in a non-endemic setting. Int J Med Microbiol. 2006;296:397-403 pubmed
    Unpreserved faecal samples, suspected to contain Entamoeba histolytica/Entamoeba dispar cysts or trophozoites on the basis of microscopic examination, and serum samples from 416 patients were collected in a prospective study to determine ..
  38. Costa C, Brito K, Gomes M, Caliari M. Morphometric study of the hepatic lesions experimentally induced in hamsters by Entamoeba dispar and E. histolytica. Parasite. 2007;14:329-34 pubmed
    Evolution of experimental hepatic lesions produced in hamsters with Entamoeba histolytica and E. dispar was evaluated quantitatively and qualitatively through morphometry and immunohistochemistry. Animals infected with E...
  39. Liang S, Hsia K, Chan Y, Fan C, Jiang D, Landt O, et al. Evaluation of a new single-tube multiprobe real-time PCR for diagnosis of Entamoeba histolytica and Entamoeba dispar. J Parasitol. 2010;96:793-7 pubmed publisher
    A single-tube multiprobe real-time PCR assay for simultaneous detection of Entamoeba histolytica and Entamoeba dispar was developed...
  40. Ramos F, Moran P, Gonzalez E, Garcia G, Ramiro M, Gomez A, et al. Entamoeba histolytica and Entamoeba dispar: prevalence infection in a rural Mexican community. Exp Parasitol. 2005;110:327-30 pubmed
    The frequency of Entamoeba histolytica and Entamoeba dispar infection was analyzed in a rural community in the state of Morelos, Mexico, through PCR technique by using specie specific primer. The E...
  41. Suzuki J, Kobayashi S, Murata R, Yanagawa Y, Takeuchi T. Profiles of a pathogenic Entamoeba histolytica-like variant with variations in the nucleotide sequence of the small subunit ribosomal RNA isolated from a primate (De Brazza's guenon). J Zoo Wildl Med. 2007;38:471-4 pubmed
    A pathogenic Entamoeba histolytica-like variant (JSK2004) with genetic variations and a novel isoenzyme pattern was isolated from a De Brazza's guenon. A homology of 99.1% was found between the clones of E...
  42. Clark C, Diamond L. Intraspecific variation and phylogenetic relationships in the genus Entamoeba as revealed by riboprinting. J Eukaryot Microbiol. 1997;44:142-54 pubmed
    Eighty-seven isolates of amebae assigned to the genus Entamoeba have been studied by riboprinting (restriction enzyme polymorphism analysis of polymerase chain reaction amplified small subunit ribosomal RNA genes)...
  43. Byers J, Faigle W, Eichinger D. Colonic short-chain fatty acids inhibit encystation of Entamoeba invadens. Cell Microbiol. 2005;7:269-79 pubmed
    b>Entamoeba parasites multiply as trophozoites in the layer of mucus that overlies the colonic epithelium...
  44. Shimokawa C, Kabir M, Taniuchi M, Mondal D, Kobayashi S, Ali I, et al. Entamoeba moshkovskii is associated with diarrhea in infants and causes diarrhea and colitis in mice. J Infect Dis. 2012;206:744-51 pubmed publisher
    b>Entamoeba moshkovskii is prevalent in developing countries and morphologically indistinguishable from pathogenic Entamoeba histolytica and nonpathogenic Entamoeba dispar. It is not known if E. moshkovskii is pathogenic...
  45. Evangelopoulos A, Spanakos G, Patsoula E, Vakalis N, Legakis N. A nested, multiplex, PCR assay for the simultaneous detection and differentiation of Entamoeba histolytica and Entamoeba dispar in faeces. Ann Trop Med Parasitol. 2000;94:233-40 pubmed
    The detection of and differentiation between Entamoeba histolytica and Entamoeba dispar are of great importance, both for diagnosis and for epidemiological studies...
  46. Garcia L, Shimizu R, Bernard C. Detection of Giardia lamblia, Entamoeba histolytica/Entamoeba dispar, and Cryptosporidium parvum antigens in human fecal specimens using the triage parasite panel enzyme immunoassay. J Clin Microbiol. 2000;38:3337-40 pubmed
    ..is a new qualitative enzyme immunoassay (EIA) panel for the detection of Giardia lamblia, Entamoeba histolytica/E. dispar, and Cryptosporidium parvum in fresh or fresh, frozen, unfixed human fecal specimens...
  47. Barrón González M, Villarreal Treviño L, Verduzco Martínez J, Mata Cárdenas B, Morales Vallarta M. Entamoeba invadens: in vitro axenic encystation with a serum substitute. Exp Parasitol. 2005;110:318-21 pubmed
    The current media for axenic cultivation of Entamoeba histolytica and Entamoeba invadens are supplemented with bovine or equine serum, which provides several essential nutrients to amoebas...
  48. Hamzah Z, Petmitr S, Mungthin M, Leelayoova S, Chavalitshewinkoon Petmitr P. Differential detection of Entamoeba histolytica, Entamoeba dispar, and Entamoeba moshkovskii by a single-round PCR assay. J Clin Microbiol. 2006;44:3196-200 pubmed
    A single-round PCR assay was developed for detection and differential diagnosis of the three Entamoeba species found in humans, Entamoeba moshkovskii, Entamoeba histolytica, and Entamoeba dispar, that are morphologically identical as ..
  49. Fotedar R, Stark D, Marriott D, Ellis J, Harkness J. Entamoeba moshkovskii infections in Sydney, Australia. Eur J Clin Microbiol Infect Dis. 2008;27:133-7 pubmed
    b>Entamoeba moshkovskii is considered to be a free-living ameba, which is morphologically similar, but biochemically and genetically different, to Entamoeba histolytica and Entamoeba dispar. However, recent studies have suggested that E...
  50. Diamond L, Harlow D, Cunnick C. A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba. Trans R Soc Trop Med Hyg. 1978;72:431-2 pubmed
  51. Hellberg A, Nickel R, Lotter H, Tannich E, Bruchhaus I. Overexpression of cysteine proteinase 2 in Entamoeba histolytica or Entamoeba dispar increases amoeba-induced monolayer destruction in vitro but does not augment amoebic liver abscess formation in gerbils. Cell Microbiol. 2001;3:13-20 pubmed
    To study the role of cysteine proteinases in the pathogenicity of Entamoeba histolytica, we have attempted to overexpress the three main cysteine proteinases (EhCP1, EhCP2, EhCP5) of this parasite in trophozoites of E...
  52. Tachibana H, Cheng X, Kobayashi S, Okada Y, Itoh J, Takeuchi T. Primary structure, expression and localization of two intermediate subunit lectins of Entamoeba dispar that contain multiple CXXC motifs. Parasitology. 2007;134:1989-99 pubmed
    We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs...
  53. Tengku S, Norhayati M. Public health and clinical importance of amoebiasis in Malaysia: a review. Trop Biomed. 2011;28:194-222 pubmed
    b>Entamoeba histolytica, the causative agent of human amoebiasis remains a significant cause of morbidity and mortality in developing countries and is responsible for up to 100,000 deaths worldwide each year...
  54. Heckendorn F, N Goran E, Felger I, Vounatsou P, Yapi A, Oettli A, et al. Species-specific field testing of Entamoeba spp. in an area of high endemicity. Trans R Soc Trop Med Hyg. 2002;96:521-8 pubmed
    b>Entamoeba histolytica has been separated in recent years into 2 morphologically identical species: the apathogenic E. dispar and the pathogenic E. histolytica, only the latter being pathogenic...
  55. Wang Z, Samuelson J, Clark C, Eichinger D, Paul J, Van Dellen K, et al. Gene discovery in the Entamoeba invadens genome. Mol Biochem Parasitol. 2003;129:23-31 pubmed
    b>Entamoeba invadens, a parasite of reptiles, is a model for the study of encystation by the human enteric pathogen Entamoeba histolytica, because E. invadens form cysts in axenic culture. With approximately 0...
  56. Pinheiro S, Maciel R, Morais M, Aca I, Carvalho L, Coimbra M. Genetic characterization of Entamoeba dispar isolates in Northeast Brazil. Acta Trop. 2005;94:35-40 pubmed
    The genetic variability of Entamoeba dispar strains was investigated in 39 positive isolates on a survey of 1783 individuals from two different cities of Northeast Brazil (Recife and Macaparana) using two polymorphic species-specific ..
  57. Mirelman D, Nuchamowitz Y, Stolarsky T. Comparison of use of enzyme-linked immunosorbent assay-based kits and PCR amplification of rRNA genes for simultaneous detection of Entamoeba histolytica and E. dispar. J Clin Microbiol. 1997;35:2405-7 pubmed
    ..enzyme-linked immunosorbent assay-based kits and PCR amplification of rRNA genes to detect and differentiate Entamoeba histolytica from E. dispar was carried out. Only the Techlab kit did not cross-react with E...
  58. Beck D, Dogan N, Maro V, Sam N, Shao J, Houpt E. High prevalence of Entamoeba moshkovskii in a Tanzanian HIV population. Acta Trop. 2008;107:48-9 pubmed publisher
    b>Entamoeba moshkovskii and Entamoeba dispar are microscopically indistinguishable from the pathogenic species Entamoeba histolytica. There are limited data on the prevalence of these commensal infections from Africa...
  59. Ghabanchi J, Zibaei M, Afkar M, Sarbazie A. Prevalence of oral Entamoeba gingivalis and Trichomonas tenax in patients with periodontal disease and healthy population in Shiraz, southern Iran. Indian J Dent Res. 2010;21:89-91 pubmed publisher
    It was shown that two parasites of Entamoeba gingivalis (E. gingivalis) and Trichomonas tenax (T. tenax) may be responsible for oral parasitic infection...
  60. Furst C, Gomes M, Tafuri W, Silva E. Biological aspects of a Brazilian strain of Entamoeba dispar. Pathologica. 2002;94:22-7 pubmed
    A strain of Entamoeba dispar was characterized by clinical diagnosis, serological and electrophoretical isoenzyme analysis and by the polymorphism of a 482 bp genomic fragment analysis...
  61. Byers J, Eichinger D. Entamoeba invadens: restriction of ploidy by colonic short chain fatty acids. Exp Parasitol. 2005;110:203-6 pubmed
    The DNA content of Entamoeba parasites appears to be regulated by an unusual mechanism...
  62. Parija S, Khairnar K. Entamoeba moshkovskii and Entamoeba dispar-associated infections in pondicherry, India. J Health Popul Nutr. 2005;23:292-5 pubmed
    The prevalence of Laredo strain--Entamoeba moshkovskii--and non-pathogenic E. dispar in patients attending the Jawaharlal Institute of Postgraduate Medical Education and Research hospital, Pondicherry, India, is reported here. E...
  63. Leitsch D, Wilson I, Paschinger K, Duchene M. Comparison of the proteome profiles of Entamoeba histolytica and its close but non-pathogenic relative Entamoeba dispar. Wien Klin Wochenschr. 2006;118:37-41 pubmed
    The microaerophilic protist Entamoeba histolytica is a source of considerable morbidity and mortality in many countries of the world by acting as a causative agent of amoebic dysentery and liver abscess...
  64. Nazemalhosseini Mojarad E, Haghighi A, Kazemi B, Rostami Nejad M, Abadi A, Zali M. High genetic diversity among Iranian Entamoeba dispar isolates based on the noncoding short tandem repeat locus D-A. Acta Trop. 2009;111:133-6 pubmed publisher
    ..the structure of locus D-A, a noncoding short tandem repeat (STR) region, also known as locus 1-2, in Iranian Entamoeba dispar isolates...
  65. Ximenez C, Cerritos R, Rojas L, Dolabella S, Moran P, Shibayama M, et al. Human amebiasis: breaking the paradigm?. Int J Environ Res Public Health. 2010;7:1105-20 pubmed publisher
    For over 30 years it has been established that the Entamoeba histolytica protozoan included two biologically and genetically different species, one with a pathogenic phenotype called E...
  66. Eichinger D. Encystation in parasitic protozoa. Curr Opin Microbiol. 2001;4:421-6 pubmed
    Giardia and Entamoeba parasites encase themselves in a carbohydrate-rich cyst for travel from host to host...
  67. Picazarri K, Nakada Tsukui K, Nozaki T. Autophagy during proliferation and encystation in the protozoan parasite Entamoeba invadens. Infect Immun. 2008;76:278-88 pubmed
    ..The intestinal protozoan parasite Entamoeba histolytica and a related reptilian species, Entamoeba invadens, possess the Atg8 conjugation system, consisting ..
  68. Aurrecoechea C, Barreto A, Brestelli J, Brunk B, Caler E, Fischer S, et al. AmoebaDB and MicrosporidiaDB: functional genomic resources for Amoebozoa and Microsporidia species. Nucleic Acids Res. 2011;39:D612-9 pubmed publisher
    ..AmoebaDB contains the genomes of three Entamoeba species (E. dispar, E. invadens and E. histolityca) and microarray expression data for E. histolytica...
  69. Makioka A, Kumagai M, Ohtomo H, Kobayashi S, Takeuchi T. Effect of cytochalasin D on the growth, encystation, and multinucleation of Entamoeba invadens. Parasitol Res. 2000;86:599-602 pubmed
    ..of cytochalasin D, a specific inhibitor of microfilaments, on the growth, encystation, and multinucleation of Entamoeba invadens was examined. Cytochalasin D blocked the growth of axenic E...
  70. Blessmann J, Van Linh P, Nu P, Thi H, Muller Myhsok B, Buss H, et al. Epidemiology of amebiasis in a region of high incidence of amebic liver abscess in central Vietnam. Am J Trop Med Hyg. 2002;66:578-83 pubmed
    The recent identification of Entamoeba dispar as a separate species, which is nonpathogenic for humans but morphologically indistinguishable from Entamoeba histolytica, has prompted the World Health Organization to recommend reinforced ..
  71. Parija S, Khairnar K. Mutation detection analysis of a region of 16S-like ribosomal RNA gene of Entamoeba histolytica, Entamoeba dispar and Entamoeba moshkovskii. BMC Infect Dis. 2008;8:131 pubmed publisher
    The level of intra-species genetic variation in Entamoeba histolytica, Entamoeba dispar and Entamoeba moshkovskii populations in a localized geographic area, like Puducherry, India, remains unknown.
  72. Eichinger D. A role for a galactose lectin and its ligands during encystment of Entamoeba. J Eukaryot Microbiol. 2001;48:17-21 pubmed
    In the life cycle of Entamoeba parasites alternate between the colon-dwelling trophozoite and the infectious cyst forms. The physiologic stimuli that trigger differentiation of trophozoites into cysts remain undefined...
  73. Weedall G, Sherrington J, Paterson S, Hall N. Evidence of gene conversion in genes encoding the Gal/GalNac lectin complex of Entamoeba. PLoS Negl Trop Dis. 2011;5:e1209 pubmed publisher
    The human gut parasite Entamoeba histolytica, uses a lectin complex on its cell surface to bind to mucin and to ligands on the intestinal epithelia...
  74. Anuar T, Al Mekhlafi H, Abdul Ghani M, Abu Bakar E, Azreen S, Salleh F, et al. Molecular epidemiology of amoebiasis in Malaysia: highlighting the different risk factors of Entamoeba histolytica and Entamoeba dispar infections among Orang Asli communities. Int J Parasitol. 2012;42:1165-75 pubmed publisher
    Currently, species-specific information on Entamoeba infections is unavailable in Malaysia and is restricted worldwide due to the re-description of pathogenic Entamoeba histolytica and non-pathogenic Entamoeba dispar and Entamoeba ..
  75. Rossignol J, Ayoub A, Ayers M. Treatment of diarrhea caused by Giardia intestinalis and Entamoeba histolytica or E. dispar: a randomized, double-blind, placebo-controlled study of nitazoxanide. J Infect Dis. 2001;184:381-4 pubmed
    ..to assess the efficacy and safety of nitazoxanide in the treatment of diarrhea caused by Giardia intestinalis or Entamoeba histolytica and/or E. dispar in 89 adults and adolescents, 22 of whom were diagnosed with G...
  76. Makioka A, Kumagai M, Kobayashi S, Takeuchi T. Possible role of calcium ions, calcium channels and calmodulin in excystation and metacystic development of Entamoeba invadens. Parasitol Res. 2002;88:837-43 pubmed
    The effect of calcium ions (Ca(2+)) and calmodulin (CaM) on the excystation and metacystic development of Entamoeba invadens was examined by transfer of cysts to a growth medium containing calcium antagonists and CaM inhibitors...
  77. Haque R, Petri W. Diagnosis of amebiasis in Bangladesh. Arch Med Res. 2006;37:273-6 pubmed
    ..histolytica was excellent. TechLab's E. histolytica- specific antigen detection test was both rapid and simple to perform, making it appropriate for use in the developing world, where amebiasis is most prevalent...
  78. Khairnar K, Parija S. A novel nested multiplex polymerase chain reaction (PCR) assay for differential detection of Entamoeba histolytica, E. moshkovskii and E. dispar DNA in stool samples. BMC Microbiol. 2007;7:47 pubmed
    ..We have developed a nested multiplex PCR targeting a 16S-like rRNA gene for differential detection of all the three morphologically similar forms of E. histolytica, E. moshkovskii and E. dispar simultaneously in stool samples...
  79. Jhingan G, Panigrahi S, Bhattacharya A, Bhattacharya S. The nucleolus in Entamoeba histolytica and Entamoeba invadens is located at the nuclear periphery. Mol Biochem Parasitol. 2009;167:72-80 pubmed publisher
    The ribosomal RNA genes in the human parasite Entamoeba histolytica and its reptilian counterpart Entamoeba invadens are located on extrachromosomal circles...
  80. Makioka A, Kumagai M, Kobayashi S, Takeuchi T. Involvement of serine proteases in the excystation and metacystic development of Entamoeba invadens. Parasitol Res. 2009;105:977-87 pubmed publisher
    Although the functions of cysteine proteases involved in the pathogenicity and differentiation of Entamoeba histolytica have been demonstrated, little is known about the functions of serine proteases...
  81. Haghighi A, Rasti S, Nazemalhosseini Mojarad E, Kazemi B, Bandehpour M, Nochi Z, et al. Entamoeba dispar: genetic diversity of Iranian isolates based on serine-rich Entamoeba dispar protein gene. Pak J Biol Sci. 2008;11:2613-8 pubmed
    The nucleotide sequences of Serine-Rich Entamoeba histolytica Protein (SREHP) gene have already exhibited stable and significant polymorphism in the gene studies...
  82. Segovia Gamboa N, Chavez Munguia B, Medina Flores Y, Cázares Raga F, Hernández Ramírez V, Martinez Palomo A, et al. Entamoeba invadens, encystation process and enolase. Exp Parasitol. 2010;125:63-9 pubmed publisher
    The reptilian parasite Entamoeba invadens is accepted as a model for the study of the Entamoeba encystation process. Here we describe the production and characterization of a mAb (B4F2), generated against a component of the E...
  83. Espinosa Cantellano M, Gonzáles Robles A, Chavez B, Castañ ón G, Arguello C, Lázaro Haller A, et al. Entamoeba dispar: ultrastructure, surface properties and cytopathic effect. J Eukaryot Microbiol. 1998;45:265-72 pubmed
    The cytological features of Entamoeba dispar, recently recognized by biochemical and molecular biology criteria as a distinct species, were compared to those of Entamoeba histolytica When cultured under axenic conditions, living ..
  84. Dvorak J, Kobayashi S, Nozaki T, Takeuchi T, Matsubara C. Induction of permeability changes and death of vertebrate cells is modulated by the virulence of Entamoeba spp. isolates. Parasitol Int. 2003;52:169-73 pubmed
    Although Entamoeba histolytica is capable of inducing an apoptotic response in vertebrate cells in vitro (Cell. Microbiol...
  85. Moran P, Ramos F, Ramiro M, Curiel O, Gonzalez E, Valadez A, et al. Entamoeba histolytica and/or Entamoeba dispar: infection frequency in HIV+/AIDS patients in Mexico city. Exp Parasitol. 2005;110:331-4 pubmed
    The objective of this work was to evaluate the frequency of Entamoeba histolytica/Entamoeba dispar intestinal infection in HIV+/AIDS subjects and their HIV- close relatives or sexual partners...
  86. Clark C, Kaffashian F, Tawari B, Windsor J, Twigg Flesner A, Davies Morel M, et al. New insights into the phylogeny of Entamoeba species provided by analysis of four new small-subunit rRNA genes. Int J Syst Evol Microbiol. 2006;56:2235-9 pubmed
    Sequences of small-subunit rRNA genes have been obtained for four new isolates of Entamoeba. Phylogenetic analyses give new insights into the evolution of these organisms...
  87. Singh N, Bhattacharya S, Paul J. Entamoeba invadens: dynamics of DNA synthesis during differentiation from trophozoite to cyst. Exp Parasitol. 2011;127:329-33 pubmed publisher
    The DNA dynamics which mediate conversion of uni-nucleate trophozoite into quadrinucleate cyst in Entamoeba histolytica is not well understood...
  88. Dolabella S, Serrano Luna J, Navarro Garcia F, Cerritos R, Ximenez C, Galván Moroyoqui J, et al. Amoebic liver abscess production by Entamoeba dispar. Ann Hepatol. 2012;11:107-17 pubmed
    Although Entamoeba dispar displays a similar morphology to Entamoeba histolytica, cellular and molecular studies have revealed significant differences between these two amoebae, including the former being characterized as non-pathogenic ..
  89. Verweij J, Blotkamp J, Brienen E, Aguirre A, Polderman A. Differentiation of Entamoeba histolytica and Entamoeba dispar cysts using polymerase chain reaction on DNA isolated from faeces with spin columns. Eur J Clin Microbiol Infect Dis. 2000;19:358-61 pubmed
    Since Entamoeba histolytica and Entamoeba dispar were formally recognized as two different species at the World Health Organization (WHO)/Pan American Health Organization (PAHO)/United Nations Educational, Scientific and Cultural ..
  90. Fotedar R, Stark D, Beebe N, Marriott D, Ellis J, Harkness J. PCR detection of Entamoeba histolytica, Entamoeba dispar, and Entamoeba moshkovskii in stool samples from Sydney, Australia. J Clin Microbiol. 2007;45:1035-7 pubmed
    This study investigated the presence of Entamoeba histolytica, Entamoeba dispar, and Entamoeba moshkovskii in stool samples from a patient population in Sydney, Australia. Stool samples were tested by microscopy and PCR...
  91. Valenzuela O, Moran P, Ramos F, Cardoza J, Garcia G, Valadez A, et al. Two different chitinase genotypes in a patient with an amebic liver abscess: a case report. Am J Trop Med Hyg. 2009;80:51-4 pubmed
    The present work deals with the identification of a patient with two liver abscesses containing two different strains of Entamoeba histolytica, as defined by chitinase gene plymorphisms.
  92. Chia M, Jeng C, Hsiao S, Lee A, Chen C, Pang V. Entamoeba invadens myositis in a common water monitor lizard (Varanus salvator). Vet Pathol. 2009;46:673-6 pubmed publisher
    ..a 136-bp region of the 18S ribosomal RNA amplified by polymerase chain reaction revealed 98-100% similarity with Entamoeba invadens. Aside from intestinal and hepatic involvement, no other internal organs were affected...