theileria

Summary

Summary: A genus of tick-borne protozoa parasitic in the lymphocytes, erythrocytes, and endothelial cells of mammals. Its organisms multiply asexually and then invade erythrocytes, where they undergo no further reproduction until ingested by a transmitting tick.

Top Publications

  1. Criado Fornelio A, Martinez Marcos A, Buling Saraña A, Barba Carretero J. Molecular studies on Babesia, Theileria and Hepatozoon in southern Europe. Part I. Epizootiological aspects. Vet Parasitol. 2003;113:189-201 pubmed
    Molecular epizootiology of piroplasmids (Babesia spp., Theileria spp.) and Hepatozoon canis was studied in mammals from southern Europe (mainly from Spain, but also from Portugal and France)...
  2. Georges K, Loria G, Riili S, Greco A, Caracappa S, Jongejan F, et al. Detection of haemoparasites in cattle by reverse line blot hybridisation with a note on the distribution of ticks in Sicily. Vet Parasitol. 2001;99:273-86 pubmed
    ..polymerase chain reaction (PCR) amplified regions of 16S rRNA (Ehrlichia/Anaplasma group) or 18S rRNA (Babesia/Theileria group) genes of haemoparasites detected Theileria annulata, T. buffeli/orientalis, Babesia bovis, B. bigemina, B...
  3. Ica A, Vatansever Z, Yildirim A, Duzlu O, Inci A. Detection of Theileria and Babesia species in ticks collected from cattle. Vet Parasitol. 2007;148:156-60 pubmed
    The present study was carried out to detect tick species that infest cattle, and Theileria and Babesia species transmitted by these ticks in Kayseri province (Turkey). A total of 300 cattle were examined for tick infestations...
  4. Brígido C, da Fonseca I, Parreira R, Fazendeiro I, Do Rosario V, Centeno Lima S. Molecular and phylogenetic characterization of Theileria spp. parasites in autochthonous bovines (Mirandesa breed) in Portugal. Vet Parasitol. 2004;123:17-23 pubmed
    ..chain reaction (PCR) analysis of the bovine blood revealed that 3 out of 116 animals were infected with Theileria and/or Babesia parasites, while reverse line blot hybridisation (RLB) analysis showed that these animals were ..
  5. Ali A, Beyer D, Bakheit M, Kullmann B, Salih D, Ahmed J, et al. Influence of subculturing on gene expression in a Theileria lestoquardi-infected cell line. Vaccine. 2008;26 Suppl 6:G17-23 pubmed publisher
    In this study potential molecular markers for identification of attenuation in a Theileria lestoquardi-infected cell line to be used in vaccination trials were identified...
  6. Khukhuu A, Lan D, Long P, Ueno A, Li Y, Luo Y, et al. Molecular epidemiological survey of Theileria orientalis in Thua Thien Hue Province, Vietnam. J Vet Med Sci. 2011;73:701-5 pubmed
    b>Theileria orientalis is a benign bovine protozoan parasite that occasionally causes serious economic loss in the livestock industry. We report the findings of a molecular epidemiological survey of T...
  7. Shiels B, Langsley G, Weir W, Pain A, McKellar S, Dobbelaere D. Alteration of host cell phenotype by Theileria annulata and Theileria parva: mining for manipulators in the parasite genomes. Int J Parasitol. 2006;36:9-21 pubmed
    The apicomplexan parasites Theileria annulata and Theileria parva cause severe lymphoproliferative disorders in cattle...
  8. Cufos N, Jabbar A, de Carvalho L, Gasser R. Mutation scanning-based analysis of Theileria orientalis populations in cattle following an outbreak. Electrophoresis. 2012;33:2036-40 pubmed publisher
    Bovine theileriosis is a tick-borne disease caused by one or more hemoprotozoan parasites of the genus Theileria. In the past, Theileria infection in cattle in Australia was largely asymptomatic and recognized to be associated with ..
  9. Inokuma H, Tsuji M, Kim S, Fujimoto T, Nagata M, Hosoi E, et al. Phylogenetic analysis of Theileria sp. from sika deer, Cervus nippon, in Japan. Vet Parasitol. 2004;120:339-45 pubmed
    The 18S rRNA genes of Theileria species detected in sika deer, Cervus nippon centralis in Yamaguchi and Cervus nippon yesoensis in Hokkaido, were analyzed...

More Information

Publications93

  1. Ribeiro M, da Silveira J, Bastos C. Failure of the Amblyomma cajennense nymph to become infected by Theileria equi after feeding on acute or chronically infected horses. Exp Parasitol. 2011;128:324-7 pubmed publisher
    Tick-borne diseases in horses are caused by the intraerythrocytic protozoan parasites Theileria equi and Babesia caballi. Although T...
  2. Abutarbush S, Alqawasmeh D, Mukbel R, Al Majali A. Equine babesiosis: seroprevalence, risk factors and comparison of different diagnostic methods in Jordan. Transbound Emerg Dis. 2012;59:72-8 pubmed publisher
    ..Competitive enzyme-linked immunosorbent assay (cELISA) revealed 37 horses (14.6%) positive for Theileria equi, and none of the horses was positive for Babesia caballi...
  3. Almeria S, Castella J, Ferrer D, Ortuño A, Estrada Pena A, Gutierrez J. Bovine piroplasms in Minorca (Balearic Islands, Spain): a comparison of PCR-based and light microscopy detection. Vet Parasitol. 2001;99:249-59 pubmed
    The present study provides the first epidemiological data regarding infection by Theileria and Babesia piroplasms in cattle in Minorca. More than 94% of the studied animals were positive for the presence of Theileria sp...
  4. Heidarpour Bami M, Haddadzadeh H, Kazemi B, Khazraiinia P, Bandehpour M, Aktas M. Molecular identification of ovine Theileria species by a new PCR-RFLP method. Vet Parasitol. 2009;161:171-7 pubmed publisher
    b>Theileria spp. infect wild and domestic ruminants in the tropical and subtropical regions of the world. Two species, T. lestoquardi and T. ovis, are suspected to cause ovine theileriosis in Iran...
  5. Mealey R, Kappmeyer L, Ueti M, Wagner B, Knowles D. Protective effects of passively transferred merozoite-specific antibodies against Theileria equi in horses with severe combined immunodeficiency. Clin Vaccine Immunol. 2012;19:100-4 pubmed publisher
    b>Theileria equi immune plasma was infused into young horses (foals) with severe combined immunodeficiency. Although all foals became infected following intravenous challenge with homologous T...
  6. Shimizu S, Nojiri K, Matsunaga N, Yamane I, Minami T. Reduction in tick numbers (Haemaphysalis longicornis), mortality and incidence of Theileria sergenti infection in field-grazed calves treated with flumethrin pour-on. Vet Parasitol. 2000;92:129-38 pubmed
    ..Mortality due to Theileria sergenti infection also decreased significantly after more than 3 years of flumethrin pour-on application, ..
  7. Yin H, Luo J, Guan G, Lu B, Ma M, Zhang Q, et al. Experiments on transmission of an unidentified Theileria sp. to small ruminants with Haemaphysalis qinghaiensis and Hyalomma anatolicum anatolicum. Vet Parasitol. 2002;108:21-30 pubmed
    Experiments on the transmission of an unidentified Theileria sp. infective for small ruminants by Haemaphysalis qinghaiensis and Hyalomma anatolicum anatolicum were carried out...
  8. Kappmeyer L, Thiagarajan M, Herndon D, Ramsay J, Caler E, Djikeng A, et al. Comparative genomic analysis and phylogenetic position of Theileria equi. BMC Genomics. 2012;13:603 pubmed publisher
    ..in 1901 as Piroplasma equi, this re-emergent apicomplexan parasite was renamed Babesia equi and subsequently Theileria equi, reflecting an uncertain taxonomy...
  9. da Silveira J, Rabelo E, Ribeiro M. Detection of Theileria and Babesia in brown brocket deer (Mazama gouazoubira) and marsh deer (Blastocerus dichotomus) in the State of Minas Gerais, Brazil. Vet Parasitol. 2011;177:61-6 pubmed publisher
    Intraerythrocytic protozoan species of the genera Theileria and Babesia are known to infect both wild and domestic animals, and both are transmitted by hard-ticks of the family Ixodidae...
  10. Kamau J, de Vos A, Playford M, Salim B, Kinyanjui P, Sugimoto C. Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks. Parasit Vectors. 2011;4:22 pubmed publisher
    b>Theileria parasites cause a benign infection of cattle in parts of Australia where they are endemic, but have, in recent years, been suspected of being responsible for a number of outbreaks of disease in cattle near the coast of New ..
  11. Yu L, Zhang S, Liang W, Jin C, Jia L, Luo Y, et al. Epidemiological survey of Theileria parasite infection of cattle in Northeast China by allele-specific PCR. J Vet Med Sci. 2011;73:1509-12 pubmed
    An epidemiological survey on a Theileria parasite infection of cattle in Northeast China was carried out using allele-specific PCR and DNA sequence analysis of the major piroplasm surface protein (MPSP) gene...
  12. Galuppi R, Aureli S, Bonoli C, Caffara M, Tampieri M. Detection and molecular characterization of Theileria sp. in fallow deer (Dama dama) and ticks from an Italian natural preserve. Res Vet Sci. 2011;91:110-5 pubmed publisher
    ..6%) with Theileria sp. 3185/02 (DQ866842) and Theileria capreoli (AY726011) from roe deer...
  13. Alanazi A, Alyousif M, Hassieb M. Seroprevalence study on Theileria equi and Babesia caballi antibodies in horses from central province of Saudi Arabia. J Parasitol. 2012;98:1015-7 pubmed publisher
    ..241 sera from clinically healthy adult horses were collected from 6 locations in Saudi Arabia and examined for Theileria equi and Babesia caballi antibodies by an indirect fluorescent antibody test...
  14. Yin H, Luo J, Schnittger L, Lu B, Beyer D, Ma M, et al. Phylogenetic analysis of Theileria species transmitted by Haemaphysalis qinghaiensis. Parasitol Res. 2004;92:36-42 pubmed
    The phylogenetic relationships between six isolates of Theileria spp. infective to small ruminants, and two isolates of Theileria spp...
  15. Song K, Sang B. Prevalence of Theileria sergenti infection in Korean native cattle by polymerase chain reaction. Korean J Parasitol. 2003;41:141-5 pubmed
    ..bulls) that had not received prior treatment or been vaccinated to prevent theileriosis were examined by PCR for Theileria sergenti infection from 2001 to 2002. In our study, the parasitemia range in T...
  16. Inoue M, Van Nguyen D, Meas S, Ohashi K, Sen S, Sugimoto C, et al. Survey of Theileria parasite infection in cattle in Cambodia and Vietnam using piroplasm surface protein gene-specific polymerase chain reaction. J Vet Med Sci. 2001;63:1155-7 pubmed
    A survey of Theileria parasite infection in cattle in Cambodia and Vietnam was carried out by using allele-specific polymerase chain reaction...
  17. Martins S, Di Giulio G, Lynen G, Peters A, Rushton J. Assessing the impact of East Coast Fever immunisation by the infection and treatment method in Tanzanian pastoralist systems. Prev Vet Med. 2010;97:175-82 pubmed publisher
    ..Furthermore, the economic analysis showed that ITM generated a profit estimated to be 7250 TZS (1 USD=1300 TZS) per vaccinated calf, and demonstrated that it was a better control measure than natural infection and subsequent treatment...
  18. McFadden A, Rawdon T, Meyer J, Makin J, Morley C, Clough R, et al. An outbreak of haemolytic anaemia associated with infection of Theileria orientalis in naive cattle. N Z Vet J. 2011;59:79-85 pubmed publisher
    ..An outbreak of haemolytic anaemia occurred when 87 cattle were introduced from a presumed non-infected herd from south Otago to a herd in Northland (n=580 cows), New Zealand, where theileriosis is endemic...
  19. Ota N, Mizuno D, Kuboki N, Igarashi I, Nakamura Y, Yamashina H, et al. Epidemiological survey of Theileria orientalis infection in grazing cattle in the eastern part of Hokkaido, Japan. J Vet Med Sci. 2009;71:937-44 pubmed
    b>Theileria orientalis is one of the benign species of Theileria that is widely distributed in Japan and is sometimes responsible for serious economic losses in the livestock industry...
  20. Marsolier J, Pineau S, Medjkane S, Perichon M, Yin Q, Flemington E, et al. OncomiR addiction is generated by a miR-155 feedback loop in Theileria-transformed leukocytes. PLoS Pathog. 2013;9:e1003222 pubmed publisher
    The intracellular parasite Theileria is the only eukaryote known to transform its mammalian host cells. We investigated the host mechanisms involved in parasite-induced transformation phenotypes...
  21. Shayan P, Rahbari S. Simultaneous differentiation between Theileria spp. and Babesia spp. on stained blood smear using PCR. Parasitol Res. 2005;97:281-6 pubmed
    ..The extracted DNA was subsequently amplified using specific primers derived from Theileria heat shock protein hsp70, Theileria lestoquardi ms1-2 gene, Babesia rhoptry protein gene and piroplasms hyper ..
  22. Gebrekidan H, Hailu A, Kassahun A, Rohousova I, Maia C, Talmi Frank D, et al. Theileria infection in domestic ruminants in northern Ethiopia. Vet Parasitol. 2014;200:31-8 pubmed publisher
    Piroplasmosis caused by different tick-borne hemoprotozoan parasites of the genera Theileria and Babesia is among the most economically important infections of domestic ruminants in sub-Saharan Africa...
  23. Chaisi M, Sibeko K, Collins N, Potgieter F, Oosthuizen M. Identification of Theileria parva and Theileria sp. (buffalo) 18S rRNA gene sequence variants in the African Buffalo (Syncerus caffer) in southern Africa. Vet Parasitol. 2011;182:150-62 pubmed publisher
    b>Theileria parva is the causative agent of Corridor disease in cattle in South Africa...
  24. Criado Fornelio A, Martinez Marcos A, Buling Saraña A, Barba Carretero J. Molecular studies on Babesia, Theileria and Hepatozoon in southern Europe. Part II. Phylogenetic analysis and evolutionary history. Vet Parasitol. 2003;114:173-94 pubmed
    Following a study on molecular epizootiology of Hepatozoon canis and piroplasmids (Babesia spp. and Theileria spp.) in southern Europe, newly obtained sequences of 18s rRNA gene were used for phylogenetic analysis...
  25. Allsopp M, Cavalier Smith T, De Waal D, Allsopp B. Phylogeny and evolution of the piroplasms. Parasitology. 1994;108 ( Pt 2):147-52 pubmed
    Small subunit ribosomal RNA (srRNA) genes of three Theileria species, one Cytauxzoon and four Babesia species were amplified using the polymerase chain reaction (PCR), cloned and sequenced...
  26. Sivakumar T, Tagawa M, Yoshinari T, Ybañez A, Igarashi I, Ikehara Y, et al. PCR detection of Babesia ovata from cattle reared in Japan and clinical significance of coinfection with Theileria orientalis. J Clin Microbiol. 2012;50:2111-3 pubmed publisher
    We describe here the clinical significance of coinfection with Theileria orientalis and Babesia ovata in cattle. Anemia status in a herd of dairy cattle in Japan was investigated in relation to infection with these parasites...
  27. Cantú Martínez M, Segura Correa J, Silva Páez M, Avalos Ramirez R, Wagner G. Prevalence of antibodies to Theileria equi and Babesia caballi in horses from northeastern Mexico. J Parasitol. 2012;98:869-70 pubmed publisher
    The objective of this study was to obtain an estimate for seroprevalences of Theileria equi (Babesia equi) and Babesia caballi in horses from northeastern Mexico...
  28. Aktas M, Altay K, Dumanli N. PCR-based detection of Theileria ovis in Rhipicephalus bursa adult ticks. Vet Parasitol. 2006;140:259-63 pubmed
    ..In this study, polymerase chain reaction (PCR) was used to assess the presence of Theileria ovis in Rhipicephalus bursa ticks. We have demonstrated that the PCR enabled detection of T...
  29. Li Y, Luo J, Liu Z, Guan G, Gao J, Ma M, et al. Experimental transmission of Theileria sp. (China 1) infective for small ruminants by Haemaphysalis longicornis and Haemaphysalis qinghaiensis. Parasitol Res. 2007;101:533-8 pubmed
    The experimental transmission of a recently identified new Theileria (China 1) species pathogenic for sheep and goats in northern China is described...
  30. Shaw M. The same but different: the biology of Theileria sporozoite entry into bovine cells. Int J Parasitol. 1997;27:457-74 pubmed
    b>Theileria are important tick-transmitted protozoan parasites that infect wild Bovidae and domestic animals throughout much of the world. Much of our understanding of Theileria sporozoite invasion of bovine cells is based on work on T...
  31. Kumar S, Kumar R, Gupta A, Dwivedi S. Passive transfer of Theileria equi antibodies to neonate foals of immune tolerant mares. Vet Parasitol. 2008;151:80-5 pubmed
    Equine babesiosis, a tick transmitted haemoprotozoan disease caused by Theileria equi is globally distributed and responsible for heavy economic losses to the equine husbandry...
  32. Roy S, Penny D. Large-scale intron conservation and order-of-magnitude variation in intron loss/gain rates in apicomplexan evolution. Genome Res. 2006;16:1270-5 pubmed
    ..6% of P. falciparum intron positions in conserved regions are shared with the distantly related apicomplexan Theileria parva, whereas only 18.2% of introns in the more intron-rich T. parva are shared with P. falciparum...
  33. Yin H, Luo J, Guan G, Gao Y, Lu B, Zhang Q, et al. Transmission of an unidentified Theileria species to small ruminants by Haemaphysalis qinghaiensis ticks collected in the field. Parasitol Res. 2002;88:S25-7 pubmed
    The transmission of a recently identified Theileria species pathogenic for sheep and goats in northern China is described...
  34. von Schubert C, Xue G, Schmuckli Maurer J, Woods K, Nigg E, Dobbelaere D. The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells. PLoS Biol. 2010;8: pubmed publisher
    The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosis...
  35. Heussler V, Küenzi P, Fraga F, Schwab R, Hemmings B, Dobbelaere D. The Akt/PKB pathway is constitutively activated in Theileria-transformed leucocytes, but does not directly control constitutive NF-kappaB activation. Cell Microbiol. 2001;3:537-50 pubmed
    The intracellular protozoan parasites Theileria parva and Theileria annulata transform leucocytes by interfering with host cell signal transduction pathways...
  36. Cossio Bayugar R, Pillars R, Schlater J, Holman P. Theileria buffeli infection of a Michigan cow confirmed by small subunit ribosomal RNA gene analysis. Vet Parasitol. 2002;105:105-10 pubmed
    b>Theileria buffeli, generally a benign parasite of cattle, has been reported in animals from Texas, Missouri and North Carolina. To date, there have been no reports of the parasite in cattle residing in northern portions of the US...
  37. Silva M, Marques P, Oliva A. Detection of Babesia and Theileria species infection in cattle from Portugal using a reverse line blotting method. Vet Parasitol. 2010;174:199-205 pubmed publisher
    ..In Portugal there are at least 4 tick vectors known to be competent for the transmission of Babesia and Theileria sp...
  38. Gubbels M, Yin H, Bai Q, Liu G, Nijman I, Jongejan F. The phylogenetic position of the Theileria buffeli group in relation to other Theileria species. Parasitol Res. 2002;88:S28-32 pubmed
    b>Theileria parasites known as either T. buffeli, T. orientalis or T. sergenti share many characteristics and are referred to as the T. buffeli group...
  39. Dobbelaere D, Rottenberg S. Theileria-induced leukocyte transformation. Curr Opin Microbiol. 2003;6:377-82 pubmed
    The intracellular protozoan parasites Theileria parva and T. annulata transform the cells they infect, inducing uncontrolled proliferation...
  40. Lizundia R, Werling D, Langsley G, Ralph S. Theileria apicoplast as a target for chemotherapy. Antimicrob Agents Chemother. 2009;53:1213-7 pubmed publisher
    b>Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets...
  41. Chaussepied M, Janski N, Baumgartner M, Lizundia R, Jensen K, Weir W, et al. TGF-b2 induction regulates invasiveness of Theileria-transformed leukocytes and disease susceptibility. PLoS Pathog. 2010;6:e1001197 pubmed publisher
    b>Theileria parasites invade and transform bovine leukocytes causing either East Coast fever (T. parva), or tropical theileriosis (T. annulata)...
  42. Matjila P, Leisewitz A, Oosthuizen M, Jongejan F, Penzhorn B. Detection of a Theileria species in dogs in South Africa. Vet Parasitol. 2008;157:34-40 pubmed publisher
    A Theileria species was detected by PCR in blood samples collected from dogs in the Pietermaritzburg area and was also found in dogs presented at the Outpatients Clinic of the Onderstepoort Veterinary Academic Hospital (OVAH), in the ..
  43. Chaisi M, Collins N, Potgieter F, Oosthuizen M. Sequence variation identified in the 18S rRNA gene of Theileria mutans and Theileria velifera from the African buffalo (Syncerus caffer). Vet Parasitol. 2013;191:132-7 pubmed publisher
    The African buffalo (Syncerus caffer) is a natural reservoir host for both pathogenic and non-pathogenic Theileria species. These often occur naturally as mixed infections in buffalo...
  44. Yin H, Liu Z, Guan G, Liu A, Ma M, Ren Q, et al. Detection and differentiation of Theileria luwenshuni and T. uilenbergi infection in small ruminants by PCR. Transbound Emerg Dis. 2008;55:233-7 pubmed publisher
    b>Theileria luwenshuni and T. uilenbergi are newly identified Theileria species highly pathogenic for sheep and goats in China...
  45. Hikosaka K, Watanabe Y, Tsuji N, Kita K, Kishine H, Arisue N, et al. Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria. Mol Biol Evol. 2010;27:1107-16 pubmed publisher
    ..The closely related genera Babesia and Theileria also have small mt genomes (6.6 kb) that are monomeric linear with an organization distinct from Plasmodium...
  46. Fuehrer H, Biró N, Harl J, Worliczek H, Beiglböck C, Farkas R, et al. Molecular detection of Theileria sp. ZS TO4 in red deer (Cervus elaphus) and questing Haemaphysalis concinna ticks in Eastern Austria. Vet Parasitol. 2013;197:653-7 pubmed publisher
    b>Theileria spp. are intracellular protozoa transmitted by ixodid ticks. T. parva and T. annulata are highly pathogenic and responsible for serious disease in domestic ruminants in tropical and subtropical countries...
  47. Nagore D, García Sanmartín J, Garcia Perez A, Juste R, Hurtado A. Identification, genetic diversity and prevalence of Theileria and Babesia species in a sheep population from Northern Spain. Int J Parasitol. 2004;34:1059-67 pubmed
    The genetic diversity and prevalence of virtually all Theileria and Babesia species in a sheep population were studied using a specifically designed reverse line blot macroarray...
  48. Zaeemi M, Haddadzadeh H, Khazraiinia P, Kazemi B, Bandehpour M. Identification of different Theileria species (Theileria lestoquardi, Theileria ovis, and Theileria annulata) in naturally infected sheep using nested PCR-RFLP. Parasitol Res. 2011;108:837-43 pubmed publisher
    ..A nested PCR-restriction fragment length polymorphism (RFLP) was carried out to identification Theileria species in sheep in some area in western half of Iran (Sari, Rasht, Urmia, Ilam, and Ahvaz)...
  49. Altay K, Dumanli N, Holman P, Aktas M. Detection of Theileria ovis in naturally infected sheep by nested PCR. Vet Parasitol. 2005;127:99-104 pubmed
    A nested polymerase chain reaction (PCR) for the detection of Theileria ovis in sheep using oligonucleotide primers designed from the small subunit ribosomal RNA (SSU rRNA) gene sequence of T...
  50. Morrison W, McKeever D. Current status of vaccine development against Theileria parasites. Parasitology. 2006;133 Suppl:S169-87 pubmed
    The tick-borne protozoan parasites Theileria parva and Theileria annulata cause economically important diseases of cattle in tropical and sub-tropical regions...
  51. Gachohi J, Ngumi P, Kitala P, Skilton R. Estimating seroprevalence and variation to four tick-borne infections and determination of associated risk factors in cattle under traditional mixed farming system in Mbeere District, Kenya. Prev Vet Med. 2010;95:208-23 pubmed publisher
    A cross-sectional study of serum antibody responses of cattle to tick-borne disease (TBD) parasites (Theileria parva, Theileria mutans, Anaplasma marginale and Babesia bigemina) was conducted on traditional smallholder mixed farms in ..
  52. Li Y, Zhang X, Liu Z, Chen Z, Yang J, He H, et al. An epidemiological survey of Theileria infections in small ruminants in central China. Vet Parasitol. 2014;200:198-202 pubmed publisher
    ..was conducted, in which 256 blood samples and 250 ticks were collected from sheep and goats, and tested for Theileria uilenbergi, T. luwenshuni, and T. ovis...
  53. Sawczuk M, Maciejewska A, Adamska M, Skotarczak B. [Roe deer (Capreolus capreolus) and red deer (Cervus elaphus) as a reservoir of protozoans from Babesia and Theileria genus in north-western Poland]. Wiad Parazytol. 2005;51:243-7 pubmed
    ..Majority of Theileria spp...
  54. Hayashida K, Hara Y, Abe T, Yamasaki C, Toyoda A, Kosuge T, et al. Comparative genome analysis of three eukaryotic parasites with differing abilities to transform leukocytes reveals key mediators of Theileria-induced leukocyte transformation. MBio. 2012;3:e00204-12 pubmed publisher
    We sequenced the genome of Theileria orientalis, a tick-borne apicomplexan protozoan parasite of cattle. The focus of this study was a comparative genome analysis of T. orientalis relative to other highly pathogenic Theileria species, T...
  55. Heussler V, Sturm A, Langsley G. Regulation of host cell survival by intracellular Plasmodium and Theileria parasites. Parasitology. 2006;132 Suppl:S49-60 pubmed
    Plasmodium and Theileria parasites are obligate intracellular protozoa of the phylum Apicomplexa. Theileria infection of bovine leukocytes induces transformation of host cells and infected leukocytes can be kept indefinitely in culture...
  56. Salama A, Aboulaila M, Moussa A, Nayel M, El Sify A, Terkawi M, et al. Evaluation of in vitro and in vivo inhibitory effects of fusidic acid on Babesia and Theileria parasites. Vet Parasitol. 2013;191:1-10 pubmed publisher
    ..8, 17.3, 33.3, and 56.25 ?M for Babesia bovis, Babesia bigemina, Babesia caballi, and Theileria equi, respectively)...
  57. Lüder C, Stanway R, Chaussepied M, Langsley G, Heussler V. Intracellular survival of apicomplexan parasites and host cell modification. Int J Parasitol. 2009;39:163-73 pubmed publisher
    ..made in understanding the molecular details of these parasite-dependent effects for Plasmodium-, Toxoplasma- and Theileria-infected cells...
  58. Ge Y, Pan W, Yin H. Prevalence of Theileria infections in goats and sheep in southeastern China. Vet Parasitol. 2012;186:466-9 pubmed publisher
    ..paper, one hundred peripheral blood samples of goats and sheep from southeastern China were examined for the Theileria infection. A region of Theileria 18S rRNA gene was amplified by nested PCR in 26 samples...
  59. Butler C, Nijhof A, van der Kolk J, de Haseth O, Taoufik A, Jongejan F, et al. Repeated high dose imidocarb dipropionate treatment did not eliminate Babesia caballi from naturally infected horses as determined by PCR-reverse line blot hybridization. Vet Parasitol. 2008;151:320-2 pubmed
    ..caballi and all horses had antibodies to Theileria equi...
  60. Brown C, Ilhan T, Kirvar E, Thomas M, Wilkie G, Leemans I, et al. Theileria lestoquardi and T. annulata in cattle, sheep, and goats. In vitro and in vivo studies. Ann N Y Acad Sci. 1998;849:44-51 pubmed
    b>Theileria annulata, causing bovine tropical theileriosis, and T. lestoquardi (syn T. hirci), the agent of malignant ovine theileriosis, are both transmitted by ticks of the genus Hyalomma...
  61. Almeria S, Castella J, Ferrer D, Gutierrez J, Estrada Pena A, Sparagano O. Reverse line blot hybridization used to identify hemoprotozoa in Minorcan cattle. Ann N Y Acad Sci. 2002;969:78-82 pubmed
    ..The oligonucleotides used were those for Theileria annulata, T. buffeli, T. taurotragi, T. velifera, Babesia bigemina, B. bovis, B. divergens, and B. major...
  62. García Sanmartín J, Barandika J, Juste R, García Pérez A, Hurtado A. Distribution and molecular detection of Theileria and Babesia in questing ticks from northern Spain. Med Vet Entomol. 2008;22:318-25 pubmed publisher
    ..3%. Most were Theileria spp.-positive (7.7%), 3.0% were positive for Babesia spp. and 1.4% of ticks harboured both genera...
  63. Nagore D, García Sanmartín J, Garcia Perez A, Juste R, Hurtado A. Detection and identification of equine Theileria and Babesia species by reverse line blotting: epidemiological survey and phylogenetic analysis. Vet Parasitol. 2004;123:41-54 pubmed
    ..to develop a new and highly sensitive reverse line blot assay to detect and identify simultaneously different Theileria and Babesia species in horses...
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    Piroplasmosis in cattle is caused by tick-borne haemoprotozoan parasites of the genera Theileria and Babesia...
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    ..number of "small" species of Babesia, some of which appear to be more closely related to members of the genus Theileria. In this work, blood samples were collected from 848 randomly selected, asymptomatic dogs and from 81 ..
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    b>Theileria lestoquardi and T. annulata can occur in similar vectors, and current available probes based on the 18S rRNA gene showed cross-reaction between the two species...
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    ..We developed Theileria species-specific probes used in combination with reverse line blot hybridization assays and identified three ..
  68. Allsopp M, Lewis B, Penzhorn B. Molecular evidence for transplacental transmission of Theileria equi from carrier mares to their apparently healthy foals. Vet Parasitol. 2007;148:130-6 pubmed
    The intra-erythrocytic parasite Theileria equi is one of two tick-transmitted causative agents of equine piroplasmosis. Piroplasms of T...
  69. Inokuma H, Nagata M, Hosoi E, Itamoto K, Okuda M. Divergence of p33/34 gene of Theileria found in Cervus nippon in Japan. J Vet Med Sci. 2008;70:401-5 pubmed
    The 18S rRNA gene and the piroplasm major immunodominant protein gene (p33/34) of Theileria from various subspecies of sika deer in 8 different locations of Japan were analyzed...
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    ..8% in sheep and 8.8% in cow). Theileria ovis was found in 1 sheep, Theileria sp. in 2 sheep, Theileria buffeli in 5 cows and B. major in 1 cow...
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    ..000114% parasitized erythrocytes (PE). We further evaluated a previously reported Theileria equi-specific qPCR assay and showed that it was able to detect the 12 T...
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    ..Using the molecular techniques, two species of theileriae were detected and characterized. Theileria ovis was present mostly in healthy sheep and in Rhipicephalus ticks collected from infected sheep. Theileria sp...
  73. Bakheit M, Ahmed J, Seitzer U. Existence of splicing variants in homologues of Theileria lestoquardi clone-5 gene's transcripts in Theileria annulata and Theileria parva. Ann N Y Acad Sci. 2008;1149:212-3 pubmed publisher
    ..Homologues of clone 5 exist in Theileria annulata and T...
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    The phylogenetic relationship of Theileria and Babesia species infecting sheep and goats on the basis of their 18S RNA gene structure was addressed in the present study...
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    A reverse line blot (RLB) assay was developed for detection and specific identification of the different ovine Theileria and Babesia parasites...
  76. Miranda J, Bakheit M, Liu Z, Yin H, Mu Y, Guo S, et al. Development of a recombinant indirect ELISA for the diagnosis of Theileria sp. (China) infection in small ruminants. Parasitol Res. 2006;98:561-7 pubmed
    b>Theileria sp. (China) causes severe limitations on the development of the livestock industry in the north-west of China...
  77. Miranda J, Stumme B, Beyer D, Cruz H, Oliva A, Bakheit M, et al. Identification of antigenic proteins of a Theileria species pathogenic for small ruminants in China recognized by antisera of infected animals. Ann N Y Acad Sci. 2004;1026:161-4 pubmed
    The antigenic proteins of the piroplasm stage of Theileria species (China), the causative agent of theilerosis of small ruminants in China, were analyzed by Western blot, revealing several specific immunoreactive proteins of different ..
  78. Oura C, Bishop R, Wampande E, Lubega G, Tait A. Application of a reverse line blot assay to the study of haemoparasites in cattle in Uganda. Int J Parasitol. 2004;34:603-13 pubmed
    ..A critical question is the sensitivity, particularly in relation to detecting carrier animals. As Theileria parva is considered to be the most important pathogen in the region, we assessed the sensitivity of the RLB ..
  79. Li Y, Luo J, Guan G, Ma M, Liu A, Liu J, et al. Experimental transmission of Theileria uilenbergi infective for small ruminants by Haemaphysalis longicornis and Haemaphysalis qinghaiensis. Parasitol Res. 2009;104:1227-31 pubmed publisher
    The experimental transmission of a recently designated Theileria uilenbergi pathogenic for sheep and goats in Northern China is described...
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    Equine piroplasmosis (EP) caused by intraerythrocytic parasites (Theileria equi and Babesia caballi) is an emerging equine disease of world-wide distribution. In Pakistan, the prevalence and incidence of EP are unknown...
  81. Kim C, Blanco L, Alhassan A, Iseki H, Yokoyama N, Xuan X, et al. Diagnostic real-time PCR assay for the quantitative detection of Theileria equi from equine blood samples. Vet Parasitol. 2008;151:158-63 pubmed
    We developed a TaqMan real-time polymerase chain reaction (PCR) assay for the quantitative detection of Theileria equi from the in vitro-cultured parasite and field blood samples collected from horses living in Ghana and Brazil...
  82. Bakheit M, Scholzen T, Ahmed J, Seitzer U. Molecular characterization of a Theileria lestoquardi gene encoding for immunogenic protein splice variants. Parasitol Res. 2006;100:161-70 pubmed
    A Theileria lestoquardi schizont cDNA library was screened using sera collected from sheep recovering from a natural malignant theileriosis infection...
  83. Heussler V, Rottenberg S, Schwab R, Küenzi P, Fernandez P, McKellar S, et al. Hijacking of host cell IKK signalosomes by the transforming parasite Theileria. Science. 2002;298:1033-6 pubmed
    ..The intracellular protozoan parasite Theileria is the only eukaryote known to induce uncontrolled host cell proliferation...
  84. Leemans I, Brown D, Hooshmand Rad P, Kirvar E, Uggla A. Infectivity and cross-immunity studies of Theileria lestoquardi and Theileria annulata in sheep and cattle: I. In vivo responses. Vet Parasitol. 1999;82:179-92 pubmed
    In a series of experiments, sporozoite stabilates of a Theileria lestoquardi (Lahr) and a T...