babesia microti

Summary

Summary: A species of protozoa infecting humans via the intermediate tick vector IXODES scapularis. The other hosts are the mouse PEROMYSCUS leucopus and meadow vole MICROTUS pennsylvanicus, which are fed on by the tick. Other primates can be experimentally infected with Babesia microti.

Top Publications

  1. Bown K, Lambin X, Telford G, Ogden N, Telfer S, Woldehiwet Z, et al. Relative importance of Ixodes ricinus and Ixodes trianguliceps as vectors for Anaplasma phagocytophilum and Babesia microti in field vole (Microtus agrestis) populations. Appl Environ Microbiol. 2008;74:7118-25 pubmed publisher
    ..ricinus and I. trianguliceps in the transmission of Anaplasma phagocytophilum and Babesia microti among United Kingdom field voles (Microtus agrestis), which serve as reservoir hosts for both pathogens...
  2. Bautista C, Sandoval A, Aguilar B. Effect of high- and low-molecular-weight components of Lactobacillus casei on resistance against Babesia microti in NIH mice. Ann N Y Acad Sci. 2008;1149:152-4 pubmed publisher
    ..components (LMWc and HMWc, respectively) of Lactobacillus casei on the resistance of mice to Babesia microti infection. In the first study, 23 components were identified in a total extract of L. casei by SDS-PAGE...
  3. Herwaldt B, Neitzel D, Gorlin J, Jensen K, Perry E, Peglow W, et al. Transmission of Babesia microti in Minnesota through four blood donations from the same donor over a 6-month period. Transfusion. 2002;42:1154-8 pubmed
    Babesiosis is a tick-borne zoonosis caused by intraerythrocytic protozoa. More than 40 US cases of Babesia microti infection acquired by blood transfusion have been reported...
  4. Tonnetti L, Thorp A, Deisting B, Bachowski G, Johnson S, Wey A, et al. Babesia microti seroprevalence in Minnesota blood donors. Transfusion. 2013;53:1698-705 pubmed publisher
    ..The agent responsible for the disease, the intraerythrocytic parasite Babesia microti, is naturally transmitted to humans by a tick bite and is endemic in areas of the Northeast and Upper Midwest ..
  5. Saito Ito A, Kasahara M, Kasai M, Dantrakool A, Kawai A, Fujita H, et al. Survey of Babesia microti infection in field rodents in Japan: records of the Kobe-type in new foci and findings of a new type related to the Otsu-type. Microbiol Immunol. 2007;51:15-24 pubmed
    Of 247 rodents comprising 5 genera and 7 species collected at 17 sites throughout Japan from 2003 to 2005, Babesia microti was detected microscopically and by polymerase chain reaction (PCR) in 36 rodents comprising 2 genera and 3 ..
  6. Shimamoto Y, Sasaki M, Ikadai H, Ishizuka M, Yokoyama N, Igarashi I, et al. Downregulation of hepatic cytochrome P450 3A in mice infected with Babesia microti. J Vet Med Sci. 2012;74:241-5 pubmed
    ..Since TNF-? is one of the potent mediators that induce NOS2 and repress CYP3A transcription, the possible involvement of TNF-? in this downregulation of CYP3A was discussed. ..
  7. Welc Faleciak R, Bajer A, Bednarska M, Paziewska A, Sinski E. Long term monitoring of Babesia microti infection in BALB/c mice using nested PCR. Ann Agric Environ Med. 2007;14:287-90 pubmed
    ..microti in the blood of rodent hosts, and could therefore be a tool for environmental monitoring of naturally infected rodents which are the predominant source of infection for tick vectors. ..
  8. Johnson S, Cable R, Tonnetti L, Spencer B, Rios J, Leiby D. Seroprevalence of Babesia microti in blood donors from Babesia-endemic areas of the northeastern United States: 2000 through 2007. Transfusion. 2009;49:2574-82 pubmed publisher
    Current estimates of 70 cases of transfusion-transmitted Babesia microti, with 12 associated deaths, suggest that Babesia is a growing blood safety concern. The extent of Babesia infections among blood donors has not been well defined...
  9. Anderson J, Magnarelli L. Babesiosis in Fairfield County, Connecticut. Emerg Infect Dis. 2004;10:545-6 pubmed

More Information

Publications78

  1. Tonnetti L, Eder A, Dy B, Kennedy J, Pisciotto P, Benjamin R, et al. Transfusion-transmitted Babesia microti identified through hemovigilance. Transfusion. 2009;49:2557-63 pubmed publisher
    b>Babesia microti, the primary cause of human babesiosis in the United States, is an intraerythrocytic parasite endemic to the Northeast and upper Midwest. Published studies indicate that B. microti increasingly poses a blood safety risk...
  2. Kuwayama D, Briones R. Spontaneous splenic rupture caused by Babesia microti infection. Clin Infect Dis. 2008;46:e92-5 pubmed publisher
    ..Although this complication is rare, practitioners who commonly treat patients with babesiosis should be aware of its potential occurrence. ..
  3. Magnarelli L, Stafford K, IJdo J, Fikrig E. Antibodies to whole-cell or recombinant antigens of Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti in white-footed mice. J Wildl Dis. 2006;42:732-8 pubmed
    ..period 2001 through 2003 and analyzed for antibodies to Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti. Emphasis was placed on the evaluations of highly specific recombinant VlsE or protein (p) 44 antigens of B...
  4. Alekseev A, Semenov A, Dubinina H. Evidence of Babesia microti infection in multi-infected Ixodes persulcatus ticks in Russia. Exp Appl Acarol. 2003;29:345-53 pubmed
    ..Ehrlichia spp. and tick-borne encephalitis virus (TBEV). All 7 ticks infected with Babesia microti, were also infected with other pathogens (all 7 among 417 infected ticks, zero amongst the remaining 321 ..
  5. Beck R, Vojta L, Curković S, Mrljak V, Margaletić J, Habrun B. Molecular survey of Babesia microti in wild rodents in central Croatia. Vector Borne Zoonotic Dis. 2011;11:81-3 pubmed publisher
    ..Recently, the first case of human infection with Babesia microti was confirmed in Germany, implicating the presence of zoonotic isolates...
  6. Camacho A, Guitian E, Pallas E, Gestal J, Olmeda A, Goethert H, et al. Azotemia and mortality among Babesia microti-like infected dogs. J Vet Intern Med. 2004;18:141-6 pubmed
    b>Babesia microti-like piroplasms are a recently recognized cause of illness in dogs in northwest Spain...
  7. Goethert H, Cook J, Lance E, Telford S. Fay and Rausch 1969 revisited: Babesia microti in Alaskan small mammals. J Parasitol. 2006;92:826-31 pubmed
    The Holarctic distribution of Babesia microti within small rodents implies an ancient association. A seminal report of piroplasms in Alaskan voles suggested to us the possibility that B...
  8. Cornillot E, Hadj Kaddour K, Dassouli A, Noel B, Ranwez V, Vacherie B, et al. Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti. Nucleic Acids Res. 2012;40:9102-14 pubmed publisher
    We have sequenced the genome of the emerging human pathogen Babesia microti and compared it with that of other protozoa. B...
  9. Hersh M, Tibbetts M, Strauss M, Ostfeld R, Keesing F. Reservoir competence of wildlife host species for Babesia microti. Emerg Infect Dis. 2012;18:1951-7 pubmed publisher
    Human babesiosis is an increasing health concern in the northeastern United States, where the causal agent, Babesia microti, is spread through the bite of infected Ixodes scapularis ticks...
  10. Ohmori T, Adachi K, Fukuda Y, Tamahara S, Matsuki N, Ono K. Glucose uptake activity in murine red blood cells infected with Babesia microti and Babesia rodhaini. J Vet Med Sci. 2004;66:945-9 pubmed
    ..One of two systems had no kinetical difference between B. rodhaini and B. microti IRBC, however another one might have higher uptake activity in B. microti IRBC compared to that in B. rodhaini IRBC...
  11. Schulze T, Jordan R, Healy S, Roegner V. Detection of Babesia microti and Borrelia burgdorferi in host-seeking Ixodes scapularis (Acari: Ixodidae) in Monmouth County, New Jersey. J Med Entomol. 2013;50:379-83 pubmed
    The etiological agents that cause human babesiosis (Babesia microti) and Lyme disease (Borrelia burgdorferi) share a common tick vector (Ixodes scapularis Say) and rodent reservoir (Peromyscus leucopus), but because the geographical ..
  12. Herwaldt B, Linden J, Bosserman E, Young C, Olkowska D, Wilson M. Transfusion-associated babesiosis in the United States: a description of cases. Ann Intern Med. 2011;155:509-19 pubmed publisher
    ..Tickborne transmission of Babesia microti mainly occurs in 7 states in the Northeast and the upper Midwest of the United States...
  13. Birkenheuer A, Horney B, Bailey M, Scott M, Sherbert B, Catto V, et al. Babesia microti-like infections are prevalent in North American foxes. Vet Parasitol. 2010;172:179-82 pubmed publisher
    b>Babesia microti-like organisms have recently been identified as a cause of hemolytic anemia and azotemia in European dogs. A genetically and morphologically similar B...
  14. Sinski E, Bajer A, Welc R, Pawełczyk A, Ogrzewalska M, Behnke J. Babesia microti: prevalence in wild rodents and Ixodes ricinus ticks from the Mazury Lakes District of North-Eastern Poland. Int J Med Microbiol. 2006;296 Suppl 40:137-43 pubmed
    Infections of Babesia microti (Apicomplexa, Piroplasmida), a common erythroparasitic protozoon of Holarctic rodents, are not widely acknowledged in Poland...
  15. Shoemaker R, Hudnell H, House D, Van Kempen A, Pakes G. Atovaquone plus cholestyramine in patients coinfected with Babesia microti and Borrelia burgdorferi refractory to other treatment. Adv Ther. 2006;23:1-11 pubmed
    Ten percent of US patients with Lyme disease are coinfected with Babesia microti. A double-blind, placebo-controlled, crossover trial enrolled 25 patients with confirmed Borrelia burgdorferi/B microti coinfection, abnormal visual ..
  16. Luo Y, Jia H, Terkawi M, Goo Y, Kawano S, Ooka H, et al. Identification and characterization of a novel secreted antigen 1 of Babesia microti and evaluation of its potential use in enzyme-linked immunosorbent assay and immunochromatographic test. Parasitol Int. 2011;60:119-25 pubmed publisher
    Here, we identified a novel secreted antigen designated as Babesia microti secreted antigen 1 (BmSA1) by immunoscreening a B...
  17. Nakajima R, Tsuji M, Oda K, Zamoto Niikura A, Wei Q, Kawabuchi Kurata T, et al. Babesia microti-group parasites compared phylogenetically by complete sequencing of the CCTeta gene in 36 isolates. J Vet Med Sci. 2009;71:55-68 pubmed
    b>Babesia microti, the erythroparasitic cause of human babesiosis, has long been taken to be a single species because classification by parasite morphology and host spectrum blurred distinctions between the parasites...
  18. Tabara K, Arai S, Kawabuchi T, Itagaki A, Ishihara C, Satoh H, et al. Molecular survey of Babesia microti, Ehrlichia species and Candidatus neoehrlichia mikurensis in wild rodents from Shimane Prefecture, Japan. Microbiol Immunol. 2007;51:359-67 pubmed
    ..We conducted molecular surveys for Babesia microti, Ehrlichia species, and Candidatus Neoehrlichia mikurensis in 62 FUO cases and 62 wild rodents from Shimane ..
  19. Walk S, Xu G, Stull J, Rich S. Correlation between tick density and pathogen endemicity, New Hampshire. Emerg Infect Dis. 2009;15:585-7 pubmed publisher
    ..Pathogens were more prevalent in areas of high tick density, suggesting a correlation between tick establishment and pathogen endemicity. Infection rates in ticks correlated with disease frequency in humans...
  20. Tsuji M, Zamoto A, Kawabuchi T, Kataoka T, Nakajima R, Asakawa M, et al. Babesia microti-like parasites detected in Eurasian red squirrels (Sciurus vulgaris orientis) in Hokkaido, Japan. J Vet Med Sci. 2006;68:643-6 pubmed
    ..This is the first report showing molecular evidence for the presence of B. microti-like parasites in Sciuridae...
  21. Leiby D, Chung A, Gill J, Houghton R, Persing D, Badon S, et al. Demonstrable parasitemia among Connecticut blood donors with antibodies to Babesia microti. Transfusion. 2005;45:1804-10 pubmed
    Reports of transfusion-transmitted Babesia microti have risen steadily during the past several years, reflecting a concurrent increase in US cases of human babesiosis. Although several studies have measured B...
  22. Simões P, Cardoso L, Araújo M, Yisaschar Mekuzas Y, Baneth G. Babesiosis due to the canine Babesia microti-like small piroplasm in dogs-first report from Portugal and possible vertical transmission. Parasit Vectors. 2011;4:50 pubmed publisher
    ..Three German shepherd dogs - a bitch and its 2-month old pup and an unrelated male - clinically suspected of piroplasmosis were assessed for babesial infection...
  23. Zamoto A, Tsuji M, Kawabuchi T, Wei Q, Asakawa M, Ishihara C. U.S.-type Babesia microti isolated from small wild mammals in Eastern Hokkaido, Japan. J Vet Med Sci. 2004;66:919-26 pubmed
    Our previous report demonstrated that small wild rodents in Japan harbored two types of novel Babesia microti-like parasites (Kobe and Hobetsu types), but not the type widely distributed throughout the temperate zones of North American ..
  24. Holman M, Caporale D, Goldberg J, Lacombe E, Lubelczyk C, Rand P, et al. Anaplasma phagocytophilum, Babesia microti, and Borrelia burgdorferi in Ixodes scapularis, southern coastal Maine. Emerg Infect Dis. 2004;10:744-6 pubmed
    ..5%, 9.5%, and 1.9% of deer ticks were infected with Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti, respectively. In 1996 and 1997, the number of A. phagocytophilum-infected ticks markedly declined...
  25. Goethert H, Telford S. What is Babesia microti?. Parasitology. 2003;127:301-9 pubmed
    b>Babesia microti (Apicomplexa: Piroplasmida) has historically been considered a common parasite of Holarctic rodents...
  26. Goethert H, Lubelcyzk C, LaCombe E, Holman M, Rand P, Smith R, et al. Enzootic Babesia microti in Maine. J Parasitol. 2003;89:1069-71 pubmed
    Human babesiosis in the northeastern United States caused by Babesia microti (Apicomplexa: Piroplasmida) is mainly reported from coastal New England sites, where deer ticks (Ixodes dammini) are common...
  27. Krause P, McKay K, Gadbaw J, Christianson D, Closter L, Lepore T, et al. Increasing health burden of human babesiosis in endemic sites. Am J Trop Med Hyg. 2003;68:431-6 pubmed
    Human infection due to Babesia microti has been regarded as infrequent and a condition primarily affecting the elderly or immunocompromised...
  28. Skotarczak B, Rymaszewska A, Wodecka B, Sawczuk M. Molecular evidence of coinfection of Borrelia burgdorferi sensu lato, human granulocytic ehrlichiosis agent, and Babesia microti in ticks from northwestern Poland. J Parasitol. 2003;89:194-6 pubmed
    ..l.), human granulocytic ehrlichiosis (HGE) agent, and Babesia microti. Of the 533 processed ticks, 16.7% were positive for B. burgdorferi s. l., 13.3% for B. microti, and 4...
  29. Leiby D, Chung A, Cable R, Trouern Trend J, McCullough J, Homer M, et al. Relationship between tick bites and the seroprevalence of Babesia microti and Anaplasma phagocytophila (previously Ehrlichia sp.) in blood donors. Transfusion. 2002;42:1585-91 pubmed
    ..Despite an increased recognition of the threat tick-borne agents pose to blood safety, our understanding of the prevalence and transmissibility of these agents in blood donors is limited...
  30. Clark K, Savick K, Butler J. Babesia microti in rodents and raccoons from northeast Florida. J Parasitol. 2012;98:1117-21 pubmed publisher
    Human babesiosis in the United States is caused most commonly by the intraerythrocytic protozoan parasite, Babesia microti ...
  31. Hikosaka K, Tsuji N, Watanabe Y, Kishine H, Horii T, Igarashi I, et al. Novel type of linear mitochondrial genomes with dual flip-flop inversion system in apicomplexan parasites, Babesia microti and Babesia rodhaini. BMC Genomics. 2012;13:622 pubmed publisher
    ..The complete mt genomes of archaeopiroplasmid parasites, Babesia microti and Babesia rodhaini, were sequenced. The mt genomes of B. microti (11.1-kb) and B. rodhaini (6...
  32. Tokarz R, Jain K, Bennett A, Briese T, Lipkin W. Assessment of polymicrobial infections in ticks in New York state. Vector Borne Zoonotic Dis. 2010;10:217-21 pubmed publisher
    ..We determined the prevalence of polymicrobial infection with Borrelia burgdorferi, Anaplasma phagocytophilum, Babesia microti, Borrelia miyamotoi, and Powassan virus in 286 adult ticks from the two counties in New York State where Lyme ..
  33. Johnson S, Van Tassell E, Tonnetti L, Cable R, Berardi V, Leiby D. Babesia microti real-time polymerase chain reaction testing of Connecticut blood donors: potential implications for screening algorithms. Transfusion. 2013;53:2644-9 pubmed publisher
    b>Babesia microti, an intraerythrocytic parasite, has been implicated in transfusion transmission. B...
  34. Simon M, Leff J, Pandya A, Cushing M, Shaz B, Calfee D, et al. Cost-effectiveness of blood donor screening for Babesia microti in endemic regions of the United States. Transfusion. 2014;54:889-99 pubmed publisher
    b>Babesia microti is the leading reported cause of red blood cell (RBC) transfusion-transmitted infection in the United States. Donor screening assays are in development.
  35. Wielinga P, Fonville M, Sprong H, Gaasenbeek C, Borgsteede F, van der Giessen J. Persistent detection of Babesia EU1 and Babesia microti in Ixodes ricinus in the Netherlands during a 5-year surveillance: 2003-2007. Vector Borne Zoonotic Dis. 2009;9:119-22 pubmed publisher
    We report the finding of Babesia EU1 and Babesia microti in Ixodes ricinus ticks in the Netherlands...
  36. Vyas J, Telford S, Robbins G. Treatment of refractory Babesia microti infection with atovaquone-proguanil in an HIV-infected patient: case report. Clin Infect Dis. 2007;45:1588-90 pubmed publisher
    ..Atovaquone-proguanil appears to have activity against babesiosis and should be studied as a potential therapy for patients with refractory babesiosis...
  37. Birkenheuer A, Marr H, Hladio N, Acton A. Molecular evidence of prevalent dual piroplasma infections in North American raccoons (Procyon lotor). Parasitology. 2008;135:33-7 pubmed
    ..One genotype resides in the Babesia sensu stricto clade and the other in the Babesia microti-like clade...
  38. Borggraefe I, Yuan J, Telford S, Menon S, Hunter R, Shah S, et al. Babesia microti primarily invades mature erythrocytes in mice. Infect Immun. 2006;74:3204-12 pubmed
    b>Babesia microti is a tick-borne red blood cell parasite that causes babesiosis in people. Its most common vertebrate reservoir is the white-footed mouse. To determine whether B...
  39. Teal A, Habura A, Ennis J, Keithly J, Madison Antenucci S. A new real-time PCR assay for improved detection of the parasite Babesia microti. J Clin Microbiol. 2012;50:903-8 pubmed publisher
    ..to a wider variety of laboratories, we developed a real-time PCR assay targeting the 18S rRNA gene of Babesia microti, the dominant babesiosis pathogen in the United States...
  40. Kjemtrup A, Lee B, Fritz C, Evans C, Chervenak M, Conrad P. Investigation of transfusion transmission of a WA1-type babesial parasite to a premature infant in California. Transfusion. 2002;42:1482-7 pubmed
    ..The infant had received two blood transfusions, one from the father and one from an anonymous donor (Donor A). This study describes the follow-up required to identify the source and species of Babesia that infected the infant...
  41. Cornillot E, Dassouli A, Garg A, Pachikara N, Randazzo S, Depoix D, et al. Whole genome mapping and re-organization of the nuclear and mitochondrial genomes of Babesia microti isolates. PLoS ONE. 2013;8:e72657 pubmed publisher
    b>Babesia microti is the primary causative agent of human babesiosis, an emerging pathogen that causes a malaria-like illness with possible fatal outcome in immunocompromised patients. The genome sequence of the B...
  42. Magnarelli L, Williams S, Norris S, Fikrig E. Serum antibodies to Borrelia burgdorferi, Anaplasma phagocytophilum, and Babesia microti in recaptured white-footed mice. J Wildl Dis. 2013;49:294-302 pubmed publisher
    ..to measure changes in antibody titers for Borrelia burgdorferi sensu stricto, Anaplasma phagocytophilum, and Babesia microti in Peromyscus leucopus (white-footed mice)...
  43. Bloch E, Lee T, Krause P, Telford S, Montalvo L, Chafets D, et al. Development of a real-time polymerase chain reaction assay for sensitive detection and quantitation of Babesia microti infection. Transfusion. 2013;53:2299-306 pubmed publisher
    b>Babesia microti, the most frequently implicated pathogen in transfusion-transmitted babesiosis, is widely endemic in the Northeast and upper Midwestern United States...
  44. Adelson M, Rao R, Tilton R, Cabets K, Eskow E, Fein L, et al. Prevalence of Borrelia burgdorferi, Bartonella spp., Babesia microti, and Anaplasma phagocytophila in Ixodes scapularis ticks collected in Northern New Jersey. J Clin Microbiol. 2004;42:2799-801 pubmed
    ..6%), Babesia microti (8.4%), Anaplasma phagocytophila (1.9%), and Bartonella spp. (34.5%). The I...
  45. Chmielewska Badora J, Moniuszko A, Żukiewicz Sobczak W, Zwolinski J, Piatek J, Pancewicz S. Serological survey in persons occupationally exposed to tick-borne pathogens in cases of co-infections with Borrelia burgdorferi, Anaplasma phagocytophilum, Bartonella spp. and Babesia microti. Ann Agric Environ Med. 2012;19:271-4 pubmed
    ..burgdorferi, as anti-B. microti, A. phagocytophilum and Bartonella spp. antibodies are not more commonly prevalent in persons with occupational risk of tick bites than in healthy volunteers...
  46. Froberg M, Dannen D, Bernier N, Shieh W, Guarner J, Zaki S. Case report: spontaneous splenic rupture during acute parasitemia of Babesia microti. Ann Clin Lab Sci. 2008;38:390-2 pubmed
    ..Typically it causes subclinical disease, but occasionally causes acute febrile disease with hepatosplenomegaly. We report a case of spontaneous splenic rupture of a 56-yr-old man with acute Babesia microti infection.
  47. Karbowiak G. Zoonotic reservoir of Babesia microti in Poland. Pol J Microbiol. 2004;53 Suppl:61-5 pubmed
    ..evidence of human babesiosis suggests that the majority of cases are involved by Babesia divergens and Babesia microti piroplasms. As zoonotic reservoir of B. microti serve small mammals--insectivores and rodents...
  48. Terkawi M, Aboge G, Jia H, Goo Y, Ooka H, Yamagishi J, et al. Molecular and immunological characterization of Babesia gibsoni and Babesia microti heat shock protein-70. Parasite Immunol. 2009;31:328-40 pubmed publisher
    ..Taken together, these results emphasize the potential of HSP-70s as a molecular adjuvant vaccine...
  49. Weiss L. Babesiosis in humans: a treatment review. Expert Opin Pharmacother. 2002;3:1109-15 pubmed
    Human infections with Babesia species, in particular Babesia microti, are tick-borne illnesses that are being recognised with increased frequency...
  50. Jeong Y, Hong S, Cho S, Lee W, Lee S. Induction of IL-10-producing CD1dhighCD5+ regulatory B cells following Babesia microti-infection. PLoS ONE. 2012;7:e46553 pubmed publisher
    ..b>Babesia microti, an intraerythrocytic protozoan of the genus Babesia, is a major cause of the emerging human disease ..
  51. Sasaki M, Fujii Y, Iwamoto M, Ikadai H. Effect of sex steroids on Babesia microti infection in mice. Am J Trop Med Hyg. 2013;88:367-75 pubmed publisher
    ..We examined the sex-based susceptibility of various mouse strains to Babesia microti Munich strain infection...
  52. Guitian F, Camacho A, Telford S. Case-control study of canine infection by a newly recognised Babesia microti-like piroplasm. Prev Vet Med. 2003;61:137-45 pubmed
    We did a case-control study to identify risk factors for prevalent infection of dogs by a newly recognised Babesia microti-like piroplasm. Clinical manifestations and haematology of infected dogs also were described...
  53. Rodgers S, Mather T. Human Babesia microti incidence and Ixodes scapularis distribution, Rhode Island, 1998-2004. Emerg Infect Dis. 2007;13:633-5 pubmed
    ..Although the incidence of babesiosis is increasing in southern Rhode Island, large areas of the state are free of babesiosis risk...
  54. Stanczak J, Gabre R, Kruminis Łozowska W, Racewicz M, Kubica Biernat B. Ixodes ricinus as a vector of Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti in urban and suburban forests. Ann Agric Environ Med. 2004;11:109-14 pubmed
    ..human anaplasmosis (HA) and babesiosis: Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti, respectively...
  55. Leiby D. Transfusion-transmitted Babesia spp.: bull's-eye on Babesia microti. Clin Microbiol Rev. 2011;24:14-28 pubmed publisher
    ..or types of Babesia have been described in the literature as causing infection in humans, the rodent parasite Babesia microti has emerged as the focal point of human disease, especially in the United States. Not only has B...
  56. Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause P. Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program. Transfusion. 2012;52:1523-9 pubmed publisher
    ..We developed and implemented the first laboratory-based blood donor screening program for Babesia microti to help reduce and prevent transfusion-transmitted babesiosis (TTB) and report results for the initial year.
  57. Wojcik Fatla A, Cisak E, Chmielewska Badora J, Zwolinski J, Buczek A, Dutkiewicz J. Prevalence of Babesia microti in Ixodes ricinus ticks from Lublin region (eastern Poland). Ann Agric Environ Med. 2006;13:319-22 pubmed
    ..ticks collected from 5 districts of the Lublin region (eastern Poland) were examined for the presence of Babesia microti DNA by PCR and nested-PCR. As many as 74 ticks (5.4 %) were found to be infected with Babesia microti...
  58. Bautista Garfias C, Gomez M, Aguilar B, Ixta O, Martinez F, Mosqueda J. The treatment of mice with Lactobacillus casei induces protection against Babesia microti infection. Parasitol Res. 2005;97:472-7 pubmed
    ..that administration of Lactobacillus casei confers protection to mice against the intracellular protozoan Babesia microti. Mice treated with L...
  59. Bown K, Lambin X, Telford G, Heyder Bruckner D, Ogden N, Birtles R. The common shrew (Sorex araneus): a neglected host of tick-borne infections?. Vector Borne Zoonotic Dis. 2011;11:947-53 pubmed publisher
    ..7%) showed evidence of infection with Anaplasma phagocytophilum and 196 (30.3%) with Babesia microti. By comparison, of 1505 blood samples from field voles, 96 (6.4%) were positive for A...
  60. Lempereur L, De Cat A, Caron Y, Madder M, Claerebout E, Saegerman C, et al. First molecular evidence of potentially zoonotic Babesia microti and Babesia sp. EU1 in Ixodes ricinus ticks in Belgium. Vector Borne Zoonotic Dis. 2011;11:125-30 pubmed publisher
    We report the first molecular evidence of the presence of Babesia sp. EU1 and Babesia microti in Ixodes ricinus ticks in Belgium. A 1-year national survey collected 1005 ticks from cats and dogs...
  61. Zamoto A, Tsuji M, Wei Q, Cho S, Shin E, Kim T, et al. Epizootiologic survey for Babesia microti among small wild mammals in northeastern Eurasia and a geographic diversity in the beta-tubulin gene sequences. J Vet Med Sci. 2004;66:785-92 pubmed
    We previously reported that small wild rodents in Japan harbor two types of novel Babesia microti-like parasites (designated as Hobetsu and Kobe types), but not the type commonly found in the northeastern United States (U.S...
  62. Joseph J, Purtill K, Wong S, Munoz J, Teal A, Madison Antenucci S, et al. Vertical transmission of Babesia microti, United States. Emerg Infect Dis. 2012;18:1318-21 pubmed publisher
    ..We report a case of babesiosis in an infant for whom vertical transmission was suggested by evidence of Babesia spp. antibodies in the heel-stick blood sample and confirmed by detection of Babesia spp. DNA in placenta tissue...
  63. Poyraz O, Gunes T. [Seroprevalance of Babesia microti in humans living in rural areas of the Sinop region]. Turkiye Parazitol Derg. 2010;34:81-5 pubmed
    ..Babesia divergens in Europe and Babesia microti in America are the most significant etiologic agents of human babesiosis cases...
  64. Wormser G, Prasad A, Neuhaus E, Joshi S, Nowakowski J, Nelson J, et al. Emergence of resistance to azithromycin-atovaquone in immunocompromised patients with Babesia microti infection. Clin Infect Dis. 2010;50:381-6 pubmed publisher
    Babesiosis is an emerging tickborne malaria-like infection principally caused by Babesia microti. This infection typically resolves either spontaneously or after administration of a 7-10-day course of azithromycin plus atovaquone or ..
  65. Duh D, Petrovec M, Trilar T, Avsic Zupanc T. The molecular evidence of Babesia microti infection in small mammals collected in Slovenia. Parasitology. 2003;126:113-7 pubmed
    In Europe, the zoonotic cycle of Babesia microti has not been determined so far. Recently, B. microti was detected in Ixodes ricinus ticks in Slovenia by using molecular methods. In order to investigate the mammalian hosts of B...
  66. Homer M, Lodes M, Reynolds L, Zhang Y, Douglass J, McNeill P, et al. Identification and characterization of putative secreted antigens from Babesia microti. J Clin Microbiol. 2003;41:723-9 pubmed
    The need for improved diagnostic reagents to identify human long-term carriers of the zoonotic parasite Babesia microti is evidenced by numerous reported cases of transfusion-acquired infections...
  67. Wojcik Fatla A, Szymanska J, Wdowiak L, Buczek A, Dutkiewicz J. Coincidence of three pathogens (Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti) in Ixodes ricinus ticks in the Lublin macroregion. Ann Agric Environ Med. 2009;16:151-8 pubmed
    ..to determine the coincidence of 3 pathogens: Borrelia burgdorferi sensu lato, Anaplasma phagocytophilum and Babesia microti in Ixodes ricinus ticks in south-eastern Poland and to estimate the degree of infection with each of the ..
  68. Kogut S, Thill C, Prusinski M, Lee J, Backerson P, Coleman J, et al. Babesia microti, upstate New York. Emerg Infect Dis. 2005;11:476-8 pubmed
    ..An investigation to determine if Babesia microti was present in local Ixodes scapularis ticks yielded 5 positive pools in 123 pools tested, the first ..
  69. Coleman J, LeVine D, Thill C, Kuhlow C, Benach J. Babesia microti and Borrelia burgdorferi follow independent courses of infection in mice. J Infect Dis. 2005;192:1634-41 pubmed
    Reports of coinfection with Borrelia burgdorferi and Babesia microti in tick vectors, reservoir hosts, and patients have led to increased concern that synergism between the 2 organisms may result in illness more severe than that caused ..