babesia

Summary

Summary: A genus of tick-borne protozoan parasites that infests the red blood cells of mammals, including humans. There are many recognized species, and the distribution is world-wide.

Top Publications

  1. Aboulaila M, Yokoyama N, Igarashi I. Inhibitory effects of (-)-epigallocatechin-3-gallate from green tea on the growth of Babesia parasites. Parasitology. 2010;137:785-91 pubmed publisher
    ..This report describes the inhibitory effect of (-)-Epigallocatechin-3-gallate on the in vitro growth of bovine Babesia parasites and the in vivo growth of the mouse-adapted rodent babesia B. microti...
  2. Saleh M. Erythrocytic oxidative damage in crossbred cattle naturally infected with Babesia bigemina. Res Vet Sci. 2009;86:43-8 pubmed publisher
    ..oxidation as contributory factors causing anaemia in cattle (Friesian x Egyptian native breed) infected with Babesia bigemina. Blood was collected from 32 cows infected with B...
  3. García Sanmartín J, Barandika J, Juste R, García Pérez A, Hurtado A. Distribution and molecular detection of Theileria and Babesia in questing ticks from northern Spain. Med Vet Entomol. 2008;22:318-25 pubmed publisher
    ..3%. Most were Theileria spp.-positive (7.7%), 3.0% were positive for Babesia spp. and 1.4% of ticks harboured both genera...
  4. Goo Y, Jia H, Terkawi M, Aboge G, Yamagishi J, Nishikawa Y, et al. Babesia gibsoni: identification, expression, localization, and serological characterization of a Babesia gibsoni 22-kDa protein. Exp Parasitol. 2009;123:273-6 pubmed publisher
    b>Babesia gibsoni causes canine babesiosis. Here, we describe the identification and characterization of a novel gene, BgP22, containing an open reading frame of 621bp and encoding a 22-kDa protein from B...
  5. Moreau E, Jouglin M, Chauvin A, Malandrin L. Babesia divergens experimental infection of spleen-intact sheep results in long-lasting parasitemia despite a strong humoral response: preliminary results. Vet Parasitol. 2009;166:205-11 pubmed publisher
    b>Babesia divergens is an intraerythrocytic Apicomplexa and the main agent of bovine babesiosis in Europe...
  6. Rojas A, Rojas D, Montenegro V, Gutierrez R, Yasur Landau D, Baneth G. Vector-borne pathogens in dogs from Costa Rica: first molecular description of Babesia vogeli and Hepatozoon canis infections with a high prevalence of monocytic ehrlichiosis and the manifestations of co-infection. Vet Parasitol. 2014;199:121-8 pubmed publisher
    ..Ehrlichia canis was detected in 34%, Anaplasma platys in 10%, Babesia vogeli in 8%, and Hepatozoon canis in 7.5% of the blood samples. No infection was detected with Leishmania spp...
  7. Lempereur L, De Cat A, Caron Y, Madder M, Claerebout E, Saegerman C, et al. First molecular evidence of potentially zoonotic Babesia microti and Babesia sp. EU1 in Ixodes ricinus ticks in Belgium. Vector Borne Zoonotic Dis. 2011;11:125-30 pubmed publisher
    We report the first molecular evidence of the presence of Babesia sp. EU1 and Babesia microti in Ixodes ricinus ticks in Belgium. A 1-year national survey collected 1005 ticks from cats and dogs...
  8. Becker C, Malandrin L, Larcher T, Chauvin A, Bischoff E, Bonnet S. Validation of BdCCp2 as a marker for Babesia divergens sexual stages in ticks. Exp Parasitol. 2013;133:51-6 pubmed publisher
    ..a tick-transmitted disease of mammalian hosts, caused by the intraerythrocytic protozoan parasites of the genus Babesia. Transmission of Babesia parasites from the vertebrate host to the tick is mediated by sexual stages, the ..
  9. Iguchi A, Matsuu A, Fujii Y, Ikadai H, Hikasa Y. The in vitro interactions and in vivo efficacy of atovaquone and proguanil against Babesia gibsoni infection in dogs. Vet Parasitol. 2013;197:527-33 pubmed publisher
    In vitro interactions between atovaquone (ATV) and proguanil (PG) against Babesia gibsoni and the clinical efficacy of this combination therapy using Malarone(®) which is the antimalarial drug containing ATV and PG were evaluated...

More Information

Publications105 found, 100 shown here

  1. Nalubamba K, Hankanga C, Mudenda N, Masuku M. The epidemiology of canine Babesia infections in Zambia. Prev Vet Med. 2011;99:240-4 pubmed publisher
    ..A cross-sectional study was also performed to determine the levels of Babesia in a low-income society (during the dry season and the wet season of the year), where 361 samples were collected ..
  2. Terkawi M, Thekisoe O, Katsande C, Latif A, Mans B, Matthee O, et al. Serological survey of Babesia bovis and Babesia bigemina in cattle in South Africa. Vet Parasitol. 2011;182:337-42 pubmed publisher
    ..ELISA) and the standard indirect fluorescent antibody test (IFAT) to determine the serological prevalence of Babesia bovis and Babesia bigemina. The results showed that 35.3% and 39.7% of cattle were positive for B...
  3. Wielinga P, Fonville M, Sprong H, Gaasenbeek C, Borgsteede F, van der Giessen J. Persistent detection of Babesia EU1 and Babesia microti in Ixodes ricinus in the Netherlands during a 5-year surveillance: 2003-2007. Vector Borne Zoonotic Dis. 2009;9:119-22 pubmed publisher
    We report the finding of Babesia EU1 and Babesia microti in Ixodes ricinus ticks in the Netherlands...
  4. Hasle G, Bjune G, Christensson D, Røed K, Whist A, Leinaas H. Detection of Babesia divergens in southern Norway by using an immunofluorescence antibody test in cow sera. Acta Vet Scand. 2010;52:55 pubmed publisher
    The incidence of bovine babesiosis, caused by Babesia divergens (Apicomplexa: Piroplasmida) has decreased markedly since the 1930 s, but may re-emerge as a consequence of climate change and changes in legislation and pasturing practices...
  5. Vilhena H, Martinez Díaz V, Cardoso L, Vieira L, Altet L, Francino O, et al. Feline vector-borne pathogens in the north and centre of Portugal. Parasit Vectors. 2013;6:99 pubmed publisher
    ..In recent years, several clinical cases and epidemiological studies of feline vector-borne diseases (FVBD) have been reported worldwide. Nonetheless, information on FVBD agents and their prevalence in Portugal is scarce...
  6. Suarez C, NOH S. Emerging perspectives in the research of bovine babesiosis and anaplasmosis. Vet Parasitol. 2011;180:109-25 pubmed publisher
    The Babesia bovis and B...
  7. Cardoso L, Cortes H, Reis A, Rodrigues P, Simoes M, Lopes A, et al. Prevalence of Babesia microti-like infection in red foxes (Vulpes vulpes) from Portugal. Vet Parasitol. 2013;196:90-5 pubmed publisher
    ..PCR for the 18S rRNA gene of Babesia spp. followed by sequencing revealed 63 foxes positive for the Babesia microti-like piroplasm (syn...
  8. Matjila P, Carcy B, Leisewitz A, Schetters T, Jongejan F, Gorenflot A, et al. Preliminary evaluation of the BrEMA1 gene as a tool for associating babesia rossi genotypes and clinical manifestation of canine Babesiosis. J Clin Microbiol. 2009;47:3586-92 pubmed publisher
    b>Babesia rossi, an intraerythrocytic protozoan, causes a severe, often life-threatening disease of domestic dogs. Dogs treated early for B...
  9. Shigueru F, Garcia J, Vidotto M, Balarin M, Fabretti A, Gasparini M, et al. [Occurrence and molecular characterization of Babesia species in a canine hospital population in the Londrina Region, Parana State, Brazil]. Rev Bras Parasitol Vet. 2008;17 Suppl 1:277-83 pubmed
    Canine babesiosis is a worldwide disease caused by the protozoan of Babesia genus. Babesia canis and B. gibsoni are both species that naturally infect dogs...
  10. Cochez C, Lempereur L, Madder M, Claerebout E, Simons L, de Wilde N, et al. Foci report on indigenous Dermacentor reticulatus populations in Belgium and a preliminary study of associated babesiosis pathogens. Med Vet Entomol. 2012;26:355-8 pubmed publisher
    ..Ticks were found mainly from early March until the end of May and a peak in activity was apparent in March. A Babesia spp...
  11. Sivakumar T, Altangerel K, Battsetseg B, Battur B, Aboulaila M, Munkhjargal T, et al. Genetic detection of Babesia bigemina from Mongolian cattle using apical membrane antigen-1 gene-based PCR assay. Vet Parasitol. 2012;187:17-22 pubmed publisher
    We developed a new nested PCR (nPCR) assay based on the Babesia bigemina apical membrane antigen-1 (AMA-1) gene sequence for parasite-specific detection...
  12. Costa Junior L, Ribeiro M, Rembeck K, Rabelo E, Zahler Rinder M, Hirzmann J, et al. Canine babesiosis caused by Babesia canis vogeli in rural areas of the State of Minas Gerais, Brazil and factors associated with its seroprevalence. Res Vet Sci. 2009;86:257-60 pubmed publisher
    ..Plasma samples were analyzed by the indirect fluorescent antibody test for detection of anti-Babesia canis vogeli antibodies...
  13. Cantu C A, Ortega S J, Garcia Vazquez Z, Mosqueda J, Henke S, George J. Epizootiology of Babesia bovis and Babesia bigemina in free-ranging white-tailed deer in northeastern Mexico. J Parasitol. 2009;95:536-42 pubmed publisher
    ..The objectives of this study were to determine the frequency of Babesia bovis and Babesia bigemina and the prevalence of antibodies to them and identify possible risk factors for bovine ..
  14. Yeagley T, Reichard M, Hempstead J, Allen K, Parsons L, White M, et al. Detection of Babesia gibsoni and the canine small Babesia 'Spanish isolate' in blood samples obtained from dogs confiscated from dogfighting operations. J Am Vet Med Assoc. 2009;235:535-9 pubmed publisher
    To determine the prevalence of Babesia gibsoni infection in dogs that were confiscated from dogfighting operations.
  15. Kelly P, Lucas H. Failure to demonstrate Babesia, Anaplasma or Ehrlichia in thrombocytopenic dogs from St Kitts. J Infect Dev Ctries. 2009;3:561-3 pubmed
    Thrombocytopenia is common in dogs on St Kitts but there is no data on the possible etiological role played by infections with Anaplasma, Babesia and Ehrlichia, other than E. canis, which are known to occur in the Caribbean.
  16. Iseki H, Zhou L, Kim C, Inpankaew T, Sununta C, Yokoyama N, et al. Seroprevalence of Babesia infections of dairy cows in northern Thailand. Vet Parasitol. 2010;170:193-6 pubmed publisher
    ..in the northern provinces (Chiang Rai, Chiang Mai, Lumpang, and Mae Hong Sorn) were tested for antibodies against Babesia bovis and B. bigemina. Species-specific enzyme-linked (rRAP-1/CTs) were performed...
  17. Lin M, Huang H. Use of a doxycycline-enrofloxacin-metronidazole combination with/without diminazene diaceturate to treat naturally occurring canine babesiosis caused by Babesia gibsoni. Acta Vet Scand. 2010;52:27 pubmed publisher
    Canine babesiosis is an important worldwide, tick-borne disease caused by hemoprotozoan parasites of the genus Babesia. Babesia gibsoni is the predominant species that causes canine babesiosis in Taipei, Taiwan...
  18. Matijatko V, Torti M, Schetters T. Canine babesiosis in Europe: how many diseases?. Trends Parasitol. 2012;28:99-105 pubmed publisher
    ..and more recently as an emerging disease in dogs worldwide, is caused by intraerythrocytic protozoa of the genus Babesia and is transmitted by ticks...
  19. Munang andu H, Munyeme M, Nambota A, Nalubamba K, Siamudaala V. Detection of Babesia spp. in free-ranging Pukus, Kobus vardonii, on a game ranch in Zambia. Korean J Parasitol. 2011;49:437-40 pubmed publisher
    b>Babesia spp. were detected from 4 asymptomatic pukus captured on a game ranch in central Zambia in October 2008...
  20. Bosman A, Oosthuizen M, Peirce M, Venter E, Penzhorn B. Babesia lengau sp. nov., a novel Babesia species in cheetah (Acinonyx jubatus, Schreber, 1775) populations in South Africa. J Clin Microbiol. 2010;48:2703-8 pubmed publisher
    In a previous paper, we reported on a large number of cheetah blood specimens that gave positive signals only for Babesia and/or Theileria genus-specific probes on the reverse line blot (RLB) assay, indicating the presence of a novel ..
  21. Zintl A, Finnerty E, Murphy T, de Waal T, Gray J. Babesias of red deer (Cervus elaphus) in Ireland. Vet Res. 2011;42:7 pubmed publisher
    ..two different PCR protocols and subsequent sequencing suggested that at least six of the deer were infected by a babesia that, in those loci, is indistinguishable from Babesia divergens, an important tick-borne pathogen of cattle and ..
  22. Lempereur L, Lebrun M, Cuvelier P, Sépult G, Caron Y, Saegerman C, et al. Longitudinal field study on bovine Babesia spp. and Anaplasma phagocytophilum infections during a grazing season in Belgium. Parasitol Res. 2012;110:1525-30 pubmed publisher
    ..Seroprevalences to Babesia spp. were measured as 10.7%, 20%, and 12...
  23. Hildebrandt A, Gray J, Hunfeld K. Human babesiosis in Europe: what clinicians need to know. Infection. 2013;41:1057-72 pubmed publisher
    ..Hitherto unknown zoonotic Babesia spp...
  24. Malandrin L, Jouglin M, Moreau E, Chauvin A. Individual heterogeneity in erythrocyte susceptibility to Babesia divergens is a critical factor for the outcome of experimental spleen-intact sheep infections. Vet Res. 2009;40:25 pubmed publisher
    Susceptibility of sheep erythrocytes to Babesia divergens was investigated in vitro and a high inter-individual variability in their ability to support parasite population development was demonstrated, with some individuals having ..
  25. Beck R, Vojta L, Mrljak V, Marinculic A, Beck A, Zivicnjak T, et al. Diversity of Babesia and Theileria species in symptomatic and asymptomatic dogs in Croatia. Int J Parasitol. 2009;39:843-8 pubmed
    Babesiosis, the disease caused by tick-borne hematozoan parasites of the genus Babesia, is particularly common in dogs, and is caused by several "large" species of Babesia, as well as by an increasing number of "small" species of Babesia,..
  26. Sun Y, Moreau E, Chauvin A, Malandrin L. The invasion process of bovine erythrocyte by Babesia divergens: knowledge from an in vitro assay. Vet Res. 2011;42:62 pubmed publisher
    b>Babesia divergens is a tick-transmitted apicomplexan parasite for which asexual multiplication in its vertebrate hosts is restricted to erythrocytes. Current knowledge of invasion of these target cells is limited...
  27. Hussain M, Saqib M, Raza F, Muhammad G, Asi M, Mansoor M, et al. Seroprevalence of Babesia caballi and Theileria equi in five draught equine populated metropolises of Punjab, Pakistan. Vet Parasitol. 2014;202:248-56 pubmed publisher
    Equine piroplasmosis (EP) caused by intraerythrocytic parasites (Theileria equi and Babesia caballi) is an emerging equine disease of world-wide distribution. In Pakistan, the prevalence and incidence of EP are unknown...
  28. Aboulaila M, Nakamura K, Govind Y, Yokoyama N, Igarashi I. Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites. Vet Parasitol. 2010;167:19-27 pubmed publisher
    ..In the present study, the inhibitory effects of epoxomicin on the in vitro growth of bovine and equine Babesia parasites were evaluated...
  29. Hikosaka K, Watanabe Y, Tsuji N, Kita K, Kishine H, Arisue N, et al. Divergence of the mitochondrial genome structure in the apicomplexan parasites, Babesia and Theileria. Mol Biol Evol. 2010;27:1107-16 pubmed publisher
    ..The closely related genera Babesia and Theileria also have small mt genomes (6...
  30. Adaszek L, Winiarczyk S. Application of the SYBR Green real-time HRM PCR technique in the differentiation of the Babesia canis canis protozoa isolated in the areas of eastern Poland. Parasitol Res. 2010;106:1253-6 pubmed publisher
    ..the real-time polymerised chain reaction (PCR) high-resolution melting (HRM) method in the differentiation of the Babesia canis canis protozoa isolated from dogs in the areas of eastern Poland. The studies involved 20 isolates of B...
  31. Ginsberg H. Potential effects of mixed infections in ticks on transmission dynamics of pathogens: comparative analysis of published records. Exp Appl Acarol. 2008;46:29-41 pubmed publisher
    ..g., for wild animal hosts) changes in pathogen prevalence in ticks have relatively little effect on levels of transmission to reservoir hosts, and thus on natural transmission cycles. ..
  32. Gong Z, Liu G, Xie J, Chai H, Zhang L, Li Z, et al. [An indirect ELISA for the detection of Babesia caballi in equine animals]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2010;28:200-4 pubmed
    To clone and express BC48 gene of Babesia caballi, and to establish an indirect ELISA for the diagnosis of B. caballi in equine animals. The genomic DNA of B. caballi was extracted from the infected donkey blood...
  33. Hatta T, Matsubayashi M, Miyoshi T, Islam K, Alim M, Anisuzzaman -, et al. Quantitative PCR-based parasite burden estimation of Babesia gibsoni in the vector tick, Haemaphysalis longicornis (Acari: Ixodidae), fed on an experimentally infected dog. J Vet Med Sci. 2013;75:1-6 pubmed
    Most causative agents of babesiosis, Babesia parasites, are transmitted transovarially in ixodid ticks. In this study, B...
  34. Rosales R, Rangel Rivas A, Escalona A, Jordan L, Gonzatti M, Aso P, et al. Detection of Theileria equi and Babesia caballi infections in Venezuelan horses using Competitive-Inhibition ELISA and PCR. Vet Parasitol. 2013;196:37-43 pubmed publisher
    ..Antibody levels to Babesia caballi and Theileria equi were assessed in 694 equine serum samples using Competitive-Inhibition ELISA, while ..
  35. Silva M, Marques P, Oliva A. Detection of Babesia and Theileria species infection in cattle from Portugal using a reverse line blotting method. Vet Parasitol. 2010;174:199-205 pubmed publisher
    ..In Portugal there are at least 4 tick vectors known to be competent for the transmission of Babesia and Theileria sp...
  36. Becker C, Bouju Albert A, Jouglin M, Chauvin A, Malandrin L. Natural transmission of Zoonotic Babesia spp. by Ixodes ricinus ticks. Emerg Infect Dis. 2009;15:320-2 pubmed
    To determine characteristics of natural transmission of Babesia sp. EU1 and B. divergens by adult Ixodes ricinus ticks, we examined tick salivary gland contents. We found that I...
  37. Cotte V, Bonnet S, Cote M, Vayssier Taussat M. Prevalence of five pathogenic agents in questing Ixodes ricinus ticks from western France. Vector Borne Zoonotic Dis. 2010;10:723-30 pubmed publisher
    ..b>Babesia sp., and very likely Bartonella sp...
  38. Tijsse Klasen E, Jacobs J, Swart A, Fonville M, Reimerink J, Brandenburg A, et al. Small risk of developing symptomatic tick-borne diseases following a tick bite in The Netherlands. Parasit Vectors. 2011;4:17 pubmed publisher
    ..Besides its causative agent, Borrelia burgdorferi s.l., other potential pathogens like Rickettsia, Babesia and Ehrlichia species are present in Ixodes ricinus ticks...
  39. Burri C, Dupasquier C, Bastic V, Gern L. Pathogens of emerging tick-borne diseases, Anaplasma phagocytophilum, Rickettsia spp., and Babesia spp., in ixodes ticks collected from rodents at four sites in Switzerland (Canton of Bern). Vector Borne Zoonotic Dis. 2011;11:939-44 pubmed publisher
    ..and Babesia spp., in field-derived ticks that detached from 79 small mammals...
  40. Adaszek Ł, Górna M, Winiarczyk S. Electrolyte level and blood pH in dogs infected by various 18S RNA strains of Babaesia canis canis on the early stage of babesiosis. Berl Munch Tierarztl Wochenschr. 2012;125:45-51 pubmed
    ..electrolyte disturbances and blood pH changes in dogs with babesiosis and possibly show a connection between the Babesia (B.) canis strain causing the infection and the intensity of these irregularities...
  41. Bastian S, Jouglin M, Brisseau N, Malandrin L, Klegou G, L Hostis M, et al. Antibody prevalence and molecular identification of Babesia spp. In roe deer in France. J Wildl Dis. 2012;48:416-24 pubmed
    ..roe deer in various landscapes, we found that 58% of the animals (237 out of 406) were antibody positive for Babesia divergens antigen...
  42. Yoshinari T, Sivakumar T, Asada M, Battsetseg B, Huang X, Lan D, et al. A PCR based survey of Babesia ovata in cattle from various Asian, African and South American countries. J Vet Med Sci. 2013;75:211-4 pubmed
    b>Babesia ovata is a tick-transmitted hemoprotozoan parasite that infects cattle...
  43. Fukumoto S, Tamaki Y, Igarashi I, Suzuki H, Xuan X. Immunogenicity and growth inhibitory efficacy of the prime-boost immunization regime with DNA followed by recombinant vaccinia virus carrying the P29 gene of Babesia gibsoni in dogs. Exp Parasitol. 2009;123:296-301 pubmed publisher
    ..Here, we evaluated the efficacy of such a strategy against the canine Babesia gibsoni infection. The DNA (pCAGGS-P29) and recombinant vaccinia virus (vvP29) both encoding the P29 of B...
  44. Otranto D, Testini G, Dantas Torres F, Latrofa M, Diniz P, de Caprariis D, et al. Diagnosis of canine vector-borne diseases in young dogs: a longitudinal study. J Clin Microbiol. 2010;48:3316-24 pubmed publisher
    ..Overall, PCR detected the highest number of dogs infected with Anaplasma platys, Babesia vogeli, and Ehrlichia canis, whereas seroconversion was a more sensitive indicator of exposure to Leishmania ..
  45. Katargina O, Geller J, Vasilenko V, Kuznetsova T, Järvekülg L, Vene S, et al. Detection and characterization of Babesia species in Ixodes ticks in Estonia. Vector Borne Zoonotic Dis. 2011;11:923-8 pubmed publisher
    The presence of Babesia spp. was studied in 2603 Ixodes ricinus and Ixodes persulcatus ticks collected at seven sites in Estonia. By reverse line blot screening, Babesia spp. was detected in 36 (1.4%) ticks, among them 18 (0...
  46. Cantú Martínez M, Segura Correa J, Silva Páez M, Avalos Ramirez R, Wagner G. Prevalence of antibodies to Theileria equi and Babesia caballi in horses from northeastern Mexico. J Parasitol. 2012;98:869-70 pubmed publisher
    The objective of this study was to obtain an estimate for seroprevalences of Theileria equi (Babesia equi) and Babesia caballi in horses from northeastern Mexico...
  47. Schnittger L, Rodriguez A, Florin Christensen M, Morrison D. Babesia: a world emerging. Infect Genet Evol. 2012;12:1788-809 pubmed publisher
    b>Babesia are tick-transmitted hemoprotozooans that infect mammals and birds, and which are acknowledged for their major impact on farm and pet animal health and associated economic costs worldwide...
  48. Welc Faleciak R, Bajer A, Paziewska Harris A, Baumann Popczyk A, Sinski E. Diversity of Babesia in Ixodes ricinus ticks in Poland. Adv Med Sci. 2012;57:364-9 pubmed
    The aims of this study were: (1) to estimate Babesia prevalence in the most common species of tick in Poland, Ixodes ricinus, in two recreational areas (Urwita?t in the Mazury Lake District and Biela?ski Forest in Warsaw), and (2) to ..
  49. Tian Z, Luo J, Zheng J, Xie J, Shen H, Yin H, et al. Phylogenetic analysis of Babesia species in China based on Cytochrome b (COB) gene. Infect Genet Evol. 2013;13:36-40 pubmed publisher
    ..of the Cytochrome b genes (COB) was amplified by polymerase chain reaction (PCR) and sequenced from individual Babesia species. Sequence variation between Babesia species from China was 1.6-30.8%...
  50. Dkhil M, Abdel Baki A, Al Quraishy S, Abdel Moneim A. Hepatic oxidative stress in Mongolian gerbils experimentally infected with Babesia divergens. Ticks Tick Borne Dis. 2013;4:346-51 pubmed publisher
    ..damage, and histopathological alterations in hepatic tissues of Mongolian gerbils experimentally infected with Babesia divergens. It was found that parasitaemia reached approximately 77% at day 5 post-infection...
  51. Oliveira T, Furuta P, de Carvalho D, Machado R. A study of cross-reactivity in serum samples from dogs positive for Leishmania sp., Babesia canis and Ehrlichia canis in enzyme-linked immunosorbent assay and indirect fluorescent antibody test. Rev Bras Parasitol Vet. 2008;17:7-11 pubmed
    ..All serum samples from endemic areas were positive for Leishmania sp., by ELISA and IFAT, 51% positive for Babesia canis and 43% for Ehrlichia canis by IFAT...
  52. Goff W, Johnson W, Molloy J, Jorgensen W, Waldron S, Figueroa J, et al. Validation of a competitive enzyme-linked immunosorbent assay for detection of Babesia bigemina antibodies in cattle. Clin Vaccine Immunol. 2008;15:1316-21 pubmed publisher
    ..assay (cELISA) based on a broadly conserved, species-specific, B-cell epitope within the C terminus of Babesia bigemina rhoptry-associated protein 1a was validated for international use...
  53. He L, Liu Q, Quan M, Zhou D, Zhou Y, Zhao J. Molecular cloning and phylogenetic analysis of Babesia orientalis heat shock protein 70. Vet Parasitol. 2009;162:183-91 pubmed publisher
    The heat shock protein 70 (hsp70) gene of Babesia orientalis was obtained from a cDNA expression library by immunoscreening with B. orientalis infected buffalo sera...
  54. Jia H, Terkawi M, Aboge G, Goo Y, Luo Y, Li Y, et al. Characterization of a leucine aminopeptidase of Babesia gibsoni. Parasitology. 2009;136:945-52 pubmed publisher
    ..investigation in order to identify novel virulence factors, drug targets, and vaccine candidates, except in Babesia. Leucine aminopeptidases in protozoa, such as Plasmodium and Leishmania, have been identified to be involved in ..
  55. Schwint O, Ueti M, Palmer G, Kappmeyer L, Hines M, Cordes R, et al. Imidocarb dipropionate clears persistent Babesia caballi infection with elimination of transmission potential. Antimicrob Agents Chemother. 2009;53:4327-32 pubmed publisher
    ..The limited repertoire of antimicrobial agents targeted at protozoal parasites magnifies this challenge. Using Babesia caballi as both a model and a specific apicomplexan pathogen for which evidence of the elimination of ..
  56. Tsai Y, Chomel B, Chang C, Kass P, Conrad P, Chuang S. Bartonella and Babesia infections in cattle and their ticks in Taiwan. Comp Immunol Microbiol Infect Dis. 2011;34:179-87 pubmed publisher
    Bartonella and Babesia infections and the association with cattle breed and age as well as tick species infesting selected cattle herds in Taiwan were investigated...
  57. Hasle G, Leinaas H, Røed K, Øines Ø. Transport of Babesia venatorum-infected Ixodes ricinus to Norway by northward migrating passerine birds. Acta Vet Scand. 2011;53:41 pubmed publisher
    ..Rare cases of babesiosis in splenectomised humans from infection with Babesia divergens and B.venatorum have been described...
  58. Varanat M, Maggi R, Linder K, Breitschwerdt E. Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma sp. in dogs with splenic disease. J Vet Intern Med. 2011;25:1284-91 pubmed publisher
    ..The spleen plays an important role in the immunologic control or elimination of vector-transmitted, blood-borne pathogens, including Bartonella sp., Babesia sp., and hemotropic Mycoplasma sp.
  59. Tadin A, Turk N, Korva M, Margaletić J, Beck R, Vucelja M, et al. Multiple co-infections of rodents with hantaviruses, Leptospira, and Babesia in Croatia. Vector Borne Zoonotic Dis. 2012;12:388-92 pubmed publisher
    Hantaviruses, Leptospira spp., and Babesia spp. are rodent-borne pathogens present worldwide. We studied multiple co-infections of small rodents in Croatia with all three pathogens...
  60. Petrigh R, Ruybal P, Thompson C, Neumann R, Moretta R, Wilkowsky S, et al. Improved molecular tools for detection of Babesia bigemina. Ann N Y Acad Sci. 2008;1149:155-7 pubmed publisher
    Molecular detection of Babesia bigemina involves a nested PCR protocol and reverse line blot hybridization (RLBH) assay based on the 18S gene. In this study, we report the development of molecular tools for improving B...
  61. Adham F, Abd el Samie E, Gabre R, el Hussein H. Detection of tick blood parasites in Egypt using PCR assay I--Babesia bovis and Babesia bigemina. Parasitol Res. 2009;105:721-30 pubmed publisher
    b>Babesia bovis and Babesia bigemina are distributed all over the world; the etiologic agents of the animal babesiosis are considered the most important tick-borne disease...
  62. Muller H, Aysul N, Liu Z, Salih D, Karagenc T, Beyer D, et al. Development of a loop-mediated isothermal amplification (LAMP) assay for rapid diagnosis of Babesia canis infections. Transbound Emerg Dis. 2010;57:63-5 pubmed publisher
    ..b>Babesia canis belongs to the Piroplasmidae and there are three described subspecies, namely B. canis canis, B...
  63. Martins T, Gonçalves L, Capela R, Moreira R, do Rosario V, Domingos A. Effect of synthesized inhibitors on babesipain-1, a new cysteine protease from the bovine piroplasm Babesia bigemina. Transbound Emerg Dis. 2010;57:68-9 pubmed publisher
    ..One gene was identified by sequence similarity search to be homologous to the CP family in the ongoing Babesia bigemina genome sequencing project database...
  64. Adaszek Ł, Winiarczyk S. In vitro cultivation of Babesia canis canis parasites isolated from dogs in Poland. Parasitol Res. 2011;108:1303-7 pubmed publisher
    The aim of this study was to perform in vitro cultivation of Babesia canis protozoa isolated from dogs with clinical babesiosis...
  65. Cassini R, Marcer F, di Regalbono A, Cancrini G, Gabrielli S, Moretti A, et al. New insights into the epidemiology of bovine piroplasmoses in Italy. Vet Parasitol. 2012;184:77-82 pubmed publisher
    ..0%) referable to the Theileria sergenti/buffeli/orientalis group, 17 (4.3%) to Theileria annae, and 1 to Babesia divergens. Serology evidenced a prevalence of 45.4% for Babesia bovis, 17.4% for Babesia bigemina, and 34...
  66. Merino O, Almazan C, Canales M, Villar M, Moreno Cid J, Galindo R, et al. Targeting the tick protective antigen subolesin reduces vector infestations and pathogen infection by Anaplasma marginale and Babesia bigemina. Vaccine. 2011;29:8575-9 pubmed publisher
    ..In this study, we used the fact that these animals were naturally infected with Anaplasma marginale and Babesia bigemina to evaluate the effect of subolesin vaccination and gene knockdown on tick infection by these cattle ..
  67. Ionita M, Mitrea I, Pfister K, Hamel D, Buzatu C, Silaghi C. Canine babesiosis in Romania due to Babesia canis and Babesia vogeli: a molecular approach. Parasitol Res. 2012;110:1659-64 pubmed publisher
    Canine babesiosis is a tick-borne disease caused by the protozoa Babesia spp. that affects dogs worldwide...
  68. Pennisi M, Caprì A, Solano Gallego L, Lombardo G, Torina A, Masucci M. Prevalence of antibodies against Rickettsia conorii, Babesia canis, Ehrlichia canis, and Anaplasma phagocytophilum antigens in dogs from the Stretto di Messina area (Italy). Ticks Tick Borne Dis. 2012;3:315-8 pubmed publisher
    ..were to determine the seroprevalence for Rickettsia conorii, Ehrlichia canis, Anaplasma phagocytophilum, and Babesia canis in outdoor-kennelled dogs (n=249) from the Stretto di Messina (Italy) and to compare seroprevalence in 2 ..
  69. Sun Y, Liu G, Yang L, Xu R, Cao W. Babesia microti-like rodent parasites isolated from Ixodes persulcatus (Acari: Ixodidae) in Heilongjiang Province, China. Vet Parasitol. 2008;156:333-9 pubmed publisher
    A Babesia microti-like rodent parasite was isolated from the tick, Ixodes persulcatus, collected from the northern forest area of Heilongjiang province, China. The collected I...
  70. Solano Gallego L, Trotta M, Carli E, Carcy B, Caldin M, Furlanello T. Babesia canis canis and Babesia canis vogeli clinicopathological findings and DNA detection by means of PCR-RFLP in blood from Italian dogs suspected of tick-borne disease. Vet Parasitol. 2008;157:211-21 pubmed publisher
    The aims of this study were to determine the presence of Babesia spp...
  71. Peleg O, Baneth G, Eyal O, Inbar J, Harrus S. Multiplex real-time qPCR for the detection of Ehrlichia canis and Babesia canis vogeli. Vet Parasitol. 2010;173:292-9 pubmed publisher
    Ehrlichia canis and Babesia canis vogeli are two tick-borne canine pathogens with a worldwide importance. Both pathogens are transmitted by Rhipicephalus sanguineus, the brown dog tick, which has an increasing global distribution...
  72. Holman P, Carroll J, Pugh R, Davis D. Molecular detection of Babesia bovis and Babesia bigemina in white-tailed deer (Odocoileus virginianus) from Tom Green County in central Texas. Vet Parasitol. 2011;177:298-304 pubmed publisher
    ..evidence suggest that white-tailed deer in South Texas and North Mexico carry the agents of bovine babesiosis, Babesia bovis and Babesia bigemina...
  73. Schorn S, Pfister K, Reulen H, Mahling M, Silaghi C. Occurrence of Babesia spp., Rickettsia spp. and Bartonella spp. in Ixodes ricinus in Bavarian public parks, Germany. Parasit Vectors. 2011;4:135 pubmed publisher
    ..collected in public parks of different Bavarian cities in a 2-year survey (2009 and 2010) and screened for DNA of Babesia spp., Rickettsia spp. and Bartonella spp. by PCR...
  74. Hamel D, Silaghi C, Lescai D, Pfister K. Epidemiological aspects on vector-borne infections in stray and pet dogs from Romania and Hungary with focus on Babesia spp. Parasitol Res. 2012;110:1537-45 pubmed publisher
    ..Eleven different parasitic and bacterial vector-borne pathogens-Babesia canis canis, Babesia canis vogeli, Babesia gibsoni, Babesia felis-like, Hepatozoon canis, Leishmania spp...
  75. Iguchi A, Matsuu A, Ikadai H, Talukder M, Hikasa Y. Development of in vitro atovaquone-resistant Babesia gibsoni with a single-nucleotide polymorphism in cytb. Vet Parasitol. 2012;185:145-50 pubmed publisher
    An atovaquone (ATV)-resistant Babesia gibsoni was developed by in vitro exposure of uncloned wild type (WT) B. gibsoni to 800 nM ATV for 6 days...
  76. Goo Y, Aboge G, Terkawi M, Jia H, Yamagishi J, Sunaga F, et al. Four promising antigens, BgP32, BgP45, BgP47, and BgP50, for serodiagnosis of Babesia gibsoni infection were classified as B. gibsoni merozoite surface protein family. Parasitol Int. 2012;61:364-8 pubmed publisher
    We determined the molecular characteristics of four proteins, BgP32, BgP45, BgP47, and BgP50, of Babesia gibsoni...
  77. Konishi K, Sakata Y, Miyazaki N, Jia H, Goo Y, Xuan X, et al. Epidemiological survey of Babesia gibsoni infection in dogs in Japan by enzyme-linked immunosorbent assay using B. gibsoni thrombospondin-related adhesive protein antigen. Vet Parasitol. 2008;155:204-8 pubmed publisher
    A nationwide epidemiological survey of Babesia gibsoni infection in non-fighting dogs was conducted using an improved ELISA with recombinant B. gibsoni thrombospondin-related adhesive protein (BgTRAP)...
  78. Montero E, Rodriguez M, Oksov Y, Lobo C. Babesia divergens apical membrane antigen 1 and its interaction with the human red blood cell. Infect Immun. 2009;77:4783-93 pubmed publisher
    Multiple parasite ligand-erythrocyte receptor interactions must occur for successful Babesia and Plasmodium invasion of the human red cell...
  79. Brkljacić M, Matijatko V, Kis I, Kucer N, Forsek J, Rafaj R, et al. Molecular evidence of natural infection with Babesia canis canis in Croatia. Acta Vet Hung. 2010;58:39-46 pubmed publisher
    The aim of the present study was to detect and characterise the species and subspecies of Babesia spp. that cause canine babesiosis in Croatia...
  80. Martins T, Do Rosario V, Domingos A. Identification of papain-like cysteine proteases from the bovine piroplasm Babesia bigemina and evolutionary relationship of piroplasms C1 family of cysteine proteases. Exp Parasitol. 2011;127:184-94 pubmed publisher
    ..were identified by sequence similarity search to be homologous to the cysteine protease family in the ongoing Babesia bigemina genome sequencing project database and were compared with the annotated genes from the complete bovine ..
  81. He L, Feng H, Zhang Q, Zhang W, Khan M, Hu M, et al. Development and evaluation of real-time PCR assay for the detection of Babesia orientalis in water buffalo (Bubalus bubalis, Linnaeus, 1758). J Parasitol. 2011;97:1166-9 pubmed publisher
    b>Babesia orientalis is the causative agent of babesiosis in water buffalo (Bubalus babalis, Linnaeus, 1758). In this study, a TaqMan real-time PCR assay was developed for quantitative detection of B. orientalis in water buffalo...
  82. He L, Feng H, Zhang W, Zhang Q, Fang R, Wang L, et al. Occurrence of Theileria and Babesia species in water buffalo (Bubalus babalis, Linnaeus, 1758) in the Hubei province, South China. Vet Parasitol. 2012;186:490-6 pubmed publisher
    ..Theileria buffeli (19.1%) was the most frequently found species in all of the locations, followed by Babesia orientalis (8.9%), Babesia bovis (1.0%) and Babesia bigemina (0.7%). Only 12 (3...
  83. Zanette M, Lima V, Laurenti M, Rossi C, Vides J, Vieira R, et al. Serological cross-reactivity of Trypanosoma cruzi, Ehrlichia canis, Toxoplasma gondii, Neospora caninum and Babesia canis to Leishmania infantum chagasi tests in dogs. Rev Soc Bras Med Trop. 2014;47:105-7 pubmed publisher
    ..The aim of this study was to evaluate the serological cross-reactivity between Leishmania sp. and other canine pathogens...
  84. Matjila P, Leisewitz A, Jongejan F, Bertschinger H, Penzhorn B. Molecular detection of Babesia rossi and Hepatozoon sp. in African wild dogs (Lycaon pictus) in South Africa. Vet Parasitol. 2008;157:123-7 pubmed publisher
    ..Specimens were screened for Babesia, Theileria, Hepatozoon and Ehrlichia/Anaplasma species using PCR and Reverse Line Blot (RLB) assays...
  85. Aboulaila M, Sivakumar T, Yokoyama N, Igarashi I. Inhibitory effect of terpene nerolidol on the growth of Babesia parasites. Parasitol Int. 2010;59:278-82 pubmed publisher
    ..falciparum. In the present study, the in vitro growth of four Babesia species was significantly (P<0.05) inhibited in the presence of nerolidol (IC(50)s values=21+/-1, 29.6+/-3, 26...
  86. Becker C, Malandrin L, Depoix D, Larcher T, David P, Chauvin A, et al. Identification of three CCp genes in Babesia divergens: novel markers for sexual stages parasites. Mol Biochem Parasitol. 2010;174:36-43 pubmed publisher
    b>Babesia divergens, a tick-borne protozoan parasite of red blood cells, is the main agent of bovine and human babesiosis in Europe...
  87. Baumeister S, Wiesner J, Reichenberg A, Hintz M, Bietz S, Harb O, et al. Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. PLoS ONE. 2011;6:e19334 pubmed publisher
    ..Surprisingly, the compounds are inactive against a range of apicomplexans replicating in nucleated cells, including Toxoplasma gondii...
  88. Freyburger L, Lemaitre L, Medaille C, Oberli F, Fanchon L, Bergamo P. [Comparative safety study of two commercialised vaccines against canine babesiosis induced by Babesia canis]. Parasite. 2011;18:311-8 pubmed
    ..No statistical difference has been revealed between the groups P and T evolutions...
  89. Goo Y, Lee N, Terkawi M, Luo Y, Aboge G, Nishikawa Y, et al. Development of a rapid immunochromatographic test using a recombinant thrombospondin-related adhesive protein of Babesia gibsoni. Vet Parasitol. 2012;190:595-8 pubmed publisher
    ..We developed an immunochromatographic test (ICT) with the full-length of thrombospondin-related adhesive protein of Babesia gibsoni expressed by the modified expression method...
  90. Hirata H, Ishinabe S, Jinnai M, Asakawa M, Ishihara C. Molecular characterization and phylogenetic analysis of Babesia sp. NV-1 detected from wild American Mink ( Neovison vison ) in Hokkaido, Japan. J Parasitol. 2013;99:350-2 pubmed publisher
    ..protozoan disease affecting many mammalian species worldwide, caused by the intraerythrocytic multiplication of Babesia spp. The present study aimed to detect the presence of Babesia sp. in 13 American mink from Hokkaido, Japan...
  91. Pattullo K, Wobeser G, Lockerbie B, Burgess H. Babesia odocoilei infection in a Saskatchewan elk (Cervus elaphus canadensis) herd. J Vet Diagn Invest. 2013;25:535-40 pubmed publisher
    ..Cervus elaphus canadensis) cow, presented for chronic severe weight loss and unthriftiness, was diagnosed with Babesia odocoilei infection based on blood smear evaluation, polymerase chain reaction (PCR), and DNA sequence analysis...
  92. Yabsley M, Greiner E, Tseng F, Garner M, Nordhausen R, Ziccardi M, et al. Description of novel Babesia species and associated lesions from common murres (Uria aalge) from California. J Parasitol. 2009;95:1183-8 pubmed publisher
    A novel Babesia species is described from blood collected from 3 common murres (also known as common guillemots) (Uria aalge) from California...