eimeria tenella

Summary

Summary: A species of coccidian protozoa that mainly infects domestic poultry.

Top Publications

  1. Weber F, Evans N. Immunization of broiler chicks by in ovo injection of Eimeria tenella sporozoites, sporocysts, or oocysts. Poult Sci. 2003;82:1701-7 pubmed
    Immunization of chickens by in ovo injection of Eimeria tenella parasite stages was investigated...
  2. Abdul Hafeez M, Akhtar M, Hussain I. Protective effect of egg-propagated Eimeria tenella (local isolates) gametocytes as vaccine(s) against mixed species of coccidia in chickens. Parasitol Res. 2006;98:539-44 pubmed
    Egg propagated gametocytes of Eimeria tenella (local isolates) were used to prepare the adjuvanted (Amphigen) and nonadjuvanted vaccine(s) and evaluated on the basis of cellular, humoral, and challenge responses...
  3. Hong Y, Lillehoj H, Lee S, Dalloul R, Lillehoj E. Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections. Vet Immunol Immunopathol. 2006;114:209-23 pubmed
    ..chicken cytokines and chemokines were quantified in intestinal lymphocytes following Eimeria acervulina and Eimeria tenella primary and secondary infections...
  4. Yang G, Li J, Zhang X, Zhao Q, Liu Q, Gong P. Eimeria tenella: construction of a recombinant fowlpox virus expressing rhomboid gene and its protective efficacy against homologous infection. Exp Parasitol. 2008;119:30-6 pubmed publisher
    A recombinant fowlpox virus (rFPV) expressing the Eimeria tenella rhomboid gene was constructed and its protective efficacy against homologous infection in chickens determined...
  5. Réfega S, Girard Misguich F, Bourdieu C, Péry P, Labbé M. Gene discovery in Eimeria tenella by immunoscreening cDNA expression libraries of sporozoites and schizonts with chicken intestinal antibodies. Vet Parasitol. 2003;113:19-33 pubmed
    Specific antibodies were produced ex vivo from intestinal culture of Eimeria tenella infected chickens. The specificity of these intestinal antibodies was tested against different parasite stages...
  6. Youn H, Noh J. Screening of the anticoccidial effects of herb extracts against Eimeria tenella. Vet Parasitol. 2001;96:257-63 pubmed
    ..herbs, including Bupleurum chinese DC, Sophora flavescens Aiton, and Artemisia annua Linne was tested against Eimeria tenella. One-day-old broiler chicks were infected with a USDA reference book of E...
  7. Klotz C, Gehre F, Lucius R, Pogonka T. Identification of Eimeria tenella genes encoding for secretory proteins and evaluation of candidates by DNA immunisation studies in chickens. Vaccine. 2007;25:6625-34 pubmed
    ..Our approach represents a rapid screening to identify and test putative new vaccine candidates from E. tenella sporozoites that could also be adopted to other apicomplexan parasites. ..
  8. Jiang L, Lin J, Han H, Zhao Q, Dong H, Zhu S, et al. Identification and partial characterization of a serine protease inhibitor (serpin) of Eimeria tenella. Parasitol Res. 2012;110:865-74 pubmed publisher
    ..In this study, a member of the serpin superfamily was identified from the common poultry parasite Eimeria tenella by expressed sequence tag analysis and the rapid amplification of cDNA ends technique...
  9. Krucken J, Hosse R, Mouafo A, Entzeroth R, Bierbaum S, Marinovski P, et al. Excystation of Eimeria tenella sporozoites impaired by antibody recognizing gametocyte/oocyst antigens GAM22 and GAM56. Eukaryot Cell. 2008;7:202-11 pubmed
    b>Eimeria tenella is the causative agent of coccidiosis in poultry. Infection of the chicken intestine begins with ingestion of sporulated oocysts releasing sporocysts, which in turn release invasive sporozoites...

More Information

Publications96

  1. Ferguson D, Campbell S, Henriquez F, Phan L, Mui E, Richards T, et al. Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella. Int J Parasitol. 2007;37:33-51 pubmed
    Apicomplexan parasites, Eimeria tenella, Plasmodium spp. and Toxoplasma gondii, possess a homologous plastid-like organelle termed the apicoplast, derived from the endosymbiotic enslavement of a photosynthetic alga...
  2. Chow Y, Wan K, Blake D, Tomley F, Nathan S. Immunogenic Eimeria tenella glycosylphosphatidylinositol-anchored surface antigens (SAGs) induce inflammatory responses in avian macrophages. PLoS ONE. 2011;6:e25233 pubmed publisher
    ..GPI)-anchored surface antigens (SAGs) are expressed specifically by second-generation merozoites of Eimeria tenella, but the ability of these proteins to stimulate immune responses in the chicken is unknown...
  3. de Venevelles P, François Chich J, Faigle W, Lombard B, Loew D, Péry P, et al. Study of proteins associated with the Eimeria tenella refractile body by a proteomic approach. Int J Parasitol. 2006;36:1399-407 pubmed
    ..In order to study their proteome, RB were purified from Eimeria tenella sporozoites by a new procedure using a reversible fixation followed by centrifugation...
  4. Péroval M, Péry P, Labbé M. The heat shock protein 90 of Eimeria tenella is essential for invasion of host cell and schizont growth. Int J Parasitol. 2006;36:1205-15 pubmed
    ..In this work, the importance of Hsp90 for Eimeria tenella, which is responsible for avian caecal coccidiosis, was studied. Our results show that E...
  5. Lai L, Bumstead J, Liu Y, Garnett J, Campanero Rhodes M, Blake D, et al. The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella. PLoS Pathog. 2011;7:e1002296 pubmed publisher
    ..We show that the major MARR protein from Eimeria tenella, EtMIC3, is deployed at the parasite-host interface during the early stages of invasion...
  6. Shi T, Yan W, Ren H, Liu X, Suo X. Dynamic development of parasitophorous vacuole of Eimeria tenella transfected with the yellow fluorescent protein gene fused to different signal sequences from apicomplexan parasites. Parasitol Res. 2009;104:315-20 pubmed publisher
    Intracellular stages of Eimeria tenella reside within a membrane-bound parasitophorous vacuole (PV). PVs of apicomplexan parasites like E...
  7. Liu X, Shi T, Ren H, Su H, Yan W, Suo X. Restriction enzyme-mediated transfection improved transfection efficiency in vitro in Apicomplexan parasite Eimeria tenella. Mol Biochem Parasitol. 2008;161:72-5 pubmed publisher
    Genetic manipulation of Apicomplexan parasite Eimeria tenella is only in its earliest stages. In the current study, transfection of E...
  8. Zaman M, Iqbal Z, Abbas R, Khan M. Anticoccidial activity of herbal complex in broiler chickens challenged with Eimeria tenella. Parasitology. 2012;139:237-43 pubmed publisher
    ..g of the herbal complex significantly reduced the negative performance and pathogenic effects associated with Eimeria tenella challenge at a level that was comparable with amprolium when using a largely susceptible recent field isolate...
  9. Engels K, Beyer C, Suárez Fernández M, Bender F, Gassel M, Unden G, et al. Inhibition of Eimeria tenella CDK-related kinase 2: From target identification to lead compounds. ChemMedChem. 2010;5:1259-71 pubmed publisher
    ..several human- and animal-pathogenic protozoans such as Plasmodium falciparum, Toxoplasma gondii, and Eimeria tenella. E...
  10. Clark J, Oakes R, Redhead K, Crouch C, Francis M, Tomley F, et al. Eimeria species parasites as novel vaccine delivery vectors: anti-Campylobacter jejuni protective immunity induced by Eimeria tenella-delivered CjaA. Vaccine. 2012;30:2683-8 pubmed publisher
    ..The capacity of Eimeria tenella to express an exogenous antigen and induce an immune response during in vivo infection which is protective ..
  11. Alnassan A, Shehata A, Kotsch M, Lendner M, Daugschies A, Bangoura B. Embryonated chicken eggs as an alternative model for mixed Clostridium perfringens and Eimeria tenella infection in chickens. Parasitol Res. 2013;112:2299-306 pubmed publisher
    ..the present study, a new approach for testing the pathogenesis and virulence of Clostridium perfringens and Eimeria tenella dual infections as a model using the CAM of embryonated chicken eggs was developed...
  12. Jiang L, Lin J, Han H, Dong H, Zhao Q, Zhu S, et al. Identification and characterization of Eimeria tenella apical membrane antigen-1 (AMA1). PLoS ONE. 2012;7:e41115 pubmed publisher
    ..In this study, a full-length cDNA of AMA1 was identified from Eimeria tenella (Et) using expressed sequence tag and the rapid amplification of cDNA ends technique...
  13. Oakes R, Kurian D, Bromley E, Ward C, Lal K, Blake D, et al. The rhoptry proteome of Eimeria tenella sporozoites. Int J Parasitol. 2013;43:181-8 pubmed publisher
    ..the results of an extensive proteomics analysis of the rhoptry organelles from the coccidian parasite, Eimeria tenella, which is a highly pathogenic parasite of the domestic chicken causing severe caecal coccidiosis...
  14. Konjufca V, Jenkins M, Wang S, Juarez Rodriguez M, Curtiss R. Immunogenicity of recombinant attenuated Salmonella enterica serovar Typhimurium vaccine strains carrying a gene that encodes Eimeria tenella antigen SO7. Infect Immun. 2008;76:5745-53 pubmed publisher
    ..For antigen delivery via the T3SS, the Eimeria tenella gene encoding sporozoite antigen SO7 was cloned downstream of the translocation domain of the Salmonella ..
  15. Li J, Zhang X, Liu Q, Yin J, Yang J. Eimeria tenella: cloning of a novel Eimeria tenella cDNA encoding a protein related to rhomboid family from F2 hybrid strain. Exp Parasitol. 2006;113:215-20 pubmed
    A novel cDNA sequence with an open reading frame of 774 bp from Eimeria tenella F2 hybrid strain (ETRH01) was isolated from a lambda cDNA library with a monoclonal antibody against sporozoite...
  16. Clark J, Billington K, Bumstead J, Oakes R, Soon P, Sopp P, et al. A toolbox facilitating stable transfection of Eimeria species. Mol Biochem Parasitol. 2008;162:77-86 pubmed publisher
    ..Strategies to generate and stabilise populations of transfected Eimeria tenella are described here, together with the identification of optimal parameters for the transfection process...
  17. Hikosaka K, Nakai Y, Watanabe Y, Tachibana S, Arisue N, Palacpac N, et al. Concatenated mitochondrial DNA of the coccidian parasite Eimeria tenella. Mitochondrion. 2011;11:273-8 pubmed publisher
    ..To elucidate the evolutionary origin of this structural divergence, we determined the mt genome of Eimeria tenella, pathogens of coccidiosis in domestic fowls. Analysis revealed that E...
  18. Li J, Zheng J, Gong P, Zhang X. Efficacy of Eimeria tenella rhomboid-like protein as a subunit vaccine in protective immunity against homologous challenge. Parasitol Res. 2012;110:1139-45 pubmed publisher
    ..homologous challenge in chickens elicited by recombinant proteins of a rhomboid-like gene (ETRHO1) from Eimeria tenella was investigated in the present study...
  19. Fetterer R, Miska K, Lillehoj H, Barfield R. Serine protease activity in developmental stages of Eimeria tenella. J Parasitol. 2007;93:333-40 pubmed
    ..Bioinformatic analysis suggests that the Eimeria tenella genome contains several serine proteases that lack homology to trypsin...
  20. Dong H, Wang Y, Han H, Li T, Zhao Q, Zhu S, et al. Identification and characterization of an Eimeria-conserved protein in Eimeria tenella. Parasitol Res. 2014;113:735-45 pubmed publisher
    ..Homologous genes were also found in Eimeria tenella and Eimeria acervulina. Alignment of the amino acid sequences from E. tenella, E. maxima, and E...
  21. McDougald L, Hu J. Blackhead disease (Histomonas meleagridis) aggravated in broiler chickens by concurrent infection with cecal coccidiosis (Eimeria tenella). Avian Dis. 2001;45:307-12 pubmed
    ..were severe in all inoculated control groups and did not appear to be affected by the introduction of Eimeria tenella infection. However, the severity of liver lesions and number of birds positive for liver lesions of H...
  22. Lillehoj H, Li G. Nitric oxide production by macrophages stimulated with Coccidia sporozoites, lipopolysaccharide, or interferon-gamma, and its dynamic changes in SC and TK strains of chickens infected with Eimeria tenella. Avian Dis. 2004;48:244-53 pubmed
    ..b>Eimeria tenella-infected chickens produced higher levels of NO compared with noninfected controls...
  23. Pinard van der Laan M, Monvoisin J, Pery P, Hamet N, Thomas M. Comparison of outbred lines of chickens for resistance to experimental infection with coccidiosis (Eimeria tenella). Poult Sci. 1998;77:185-91 pubmed
    ..Chicks were challenged at 4 wk of age with a high dose of Eimeria tenella (150,000 oocysts) and slaughtered 8 d postinoculation...
  24. Han H, Lin J, Zhao Q, Dong H, Jiang L, Xu M, et al. Identification of differentially expressed genes in early stages of Eimeria tenella by suppression subtractive hybridization and cDNA microarray. J Parasitol. 2010;96:95-102 pubmed publisher
    ..to identify novel and important genes involved in the development and invasion of the early stages of Eimeria tenella . Three subtractive cDNA libraries were constructed for 3 stages of E...
  25. Hoogendoorn B, Toye A, Bumstead N, Shirley M. Mapping the genome of Eimeria tenella: use of a yeast artificial chromosome library as the basis for a physical map. Parasitol Res. 1998;84:13-6 pubmed
    Efforts to derive a physical map of the genome of Eimeria tenella are being made to complement genetic mapping and to assist in the production of an integrated map...
  26. Khalafalla R, Muller U, Shahiduzzaman M, Dyachenko V, Desouky A, Alber G, et al. Effects of curcumin (diferuloylmethane) on Eimeria tenella sporozoites in vitro. Parasitol Res. 2011;108:879-86 pubmed publisher
    ..Its effects were evaluated on Eimeria tenella sporozoites, including morphological alterations, sporozoite viability and infectivity to Madin-Darby bovine ..
  27. Schwarz R, Fetterer R, Rosenberg G, Miska K. Coccidian merozoite transcriptome analysis from Eimeria maxima in comparison to Eimeria tenella and Eimeria acervulina. J Parasitol. 2010;96:49-57 pubmed publisher
    ..for which transcriptome data are available, i.e., Eimeria tenella and Eimeria acervulina ...
  28. Appledorn D, Aldhamen Y, Depas W, Seregin S, Liu C, Schuldt N, et al. A new adenovirus based vaccine vector expressing an Eimeria tenella derived TLR agonist improves cellular immune responses to an antigenic target. PLoS ONE. 2010;5:e9579 pubmed publisher
  29. Shirley M, Harvey D. A genetic linkage map of the apicomplexan protozoan parasite Eimeria tenella. Genome Res. 2000;10:1587-93 pubmed
    ..A table with the segregation data is available as an online supplement at http://www.genome.org.]..
  30. Guo F, Kwakkel R, Williams B, Parmentier H, Li W, Yang Z, et al. Effects of mushroom and herb polysaccharides on cellular and humoral immune responses of Eimeria tenella-infected chickens. Poult Sci. 2004;83:1124-32 pubmed
    ..fuciformis (TreE), and an herb, Astragalus membranaceus (AstE), on cellular and humoral immune responses of Eimeria tenella-infected chickens...
  31. Akhtar M, Hafeez M, Javed M, Hussain I. Immunogenic characterization of egg-adapted gametocytes of Eimera tenella. Parasitol Res. 2006;99:293-6 pubmed
    ..Further studies on the biochemical characterization of the egg-adapted gametocyte antigen(s) and its role in E. tenella oocyst wall formation is underway...
  32. Shah M, Yan R, Xu L, Song X, Li X. A recombinant DNA vaccine encoding Eimeria acervulina cSZ-2 induces immunity against experimental E. tenella infection. Vet Parasitol. 2010;169:185-9 pubmed publisher
    ..It is concluded that co-administration of interleukin 2 can further enhance its immunity, leading towards further research...
  33. Constantinoiu C, Molloy J, Jorgensen W, Coleman G. Antibody response against endogenous stages of an attenuated strain of Eimeria tenella. Vet Parasitol. 2008;154:193-204 pubmed publisher
    ..response to the different parasite life cycle stages following infection with an attenuated strain of Eimeria tenella. Western blotting analysis of parasite antigens prepared from the lining of caeca infected with the ..
  34. Shen X, Wang C, Zhu Q, Li T, Yu L, Zheng W, et al. Effect of the diclazuril on Hsp90 in the second-generation merozoites of Eimeria tenella. Vet Parasitol. 2012;185:290-5 pubmed publisher
    b>Eimeria tenella (E. tenella) is one of the most virulent pathogens of coccidiosis. In apicomplexan parasites, Hsp90 (Heat shock protein 90) is essential for the invasion and survival in host cells...
  35. Schaeffer M, Schroeder J, Heckeroth A, Noack S, Gassel M, Mottram J, et al. Identification of lead compounds targeting the cathepsin B-like enzyme of Eimeria tenella. Antimicrob Agents Chemother. 2012;56:1190-201 pubmed publisher
    ..We have identified a single-copy cathepsin B-like cysteine peptidase gene in the genome database of Eimeria tenella (EtCatB)...
  36. Tierney J, Mulcahy G. Comparative development of Eimeria tenella (Apicomplexa) in host cells in vitro. Parasitol Res. 2003;90:301-4 pubmed
    Attempts to propagate Eimeria tenella in cell culture over the years have met with limited success. The host cell type is an important parameter in such cultures. This study assessed the ability of different host cell lines to support E...
  37. Constantinoiu C, Molloy J, Jorgensen W, Coleman G. Development and validation of an ELISA for detecting antibodies to Eimeria tenella in chickens. Vet Parasitol. 2007;150:306-13 pubmed
    The aim of this study was to develop and validate an ELISA for detecting chicken antibodies to Eimeria tenella. An initial comparison of merozoite and sporozoite antigen preparations revealed few differences in their ability to monitor ..
  38. Li L, Brunk B, Kissinger J, Pape D, Tang K, Cole R, et al. Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene database. Genome Res. 2003;13:443-54 pubmed
    ..of medical importance (Plasmodium falciparum, Toxoplasma gondii) and others of veterinary importance (Eimeria tenella, Sarcocystis neurona, and Neospora caninum)...
  39. Wang Q, Li J, Zhang X, Liu Q, Liu C, Ma G, et al. Protective immunity of recombinant Mycobacterium bovis BCG expressing rhomboid gene against Eimeria tenella challenge. Vet Parasitol. 2009;160:198-203 pubmed publisher
    Two recombinant Mycobacterium bovis BCG (rBCG) strains carrying the Eimeria tenella rhomboid gene (Rho) delivered by extrachromosomal vector pMV261 and integrative vector pMV361 were evaluated for their ability to protect chickens ..
  40. Belli S, Ferguson D, Katrib M, Slapetova I, Mai K, Slapeta J, et al. Conservation of proteins involved in oocyst wall formation in Eimeria maxima, Eimeria tenella and Eimeria acervulina. Int J Parasitol. 2009;39:1063-70 pubmed publisher
    ..maxima, Eimeria tenella and Eimeria acervulina...
  41. Michels M, Bertolini L, Esteves A, Moreira P, Franca S. Anticoccidial effects of coumestans from Eclipta alba for sustainable control of Eimeria tenella parasitosis in poultry production. Vet Parasitol. 2011;177:55-60 pubmed publisher
    ..The chicken broilers were individually infected with 2 × 104 oocysts of Eimeria tenella when they were 14 days old and were monitored weekly to evaluate zootechnical parameters such as weight gain ..
  42. Ling K, Rajandream M, Rivailler P, Ivens A, Yap S, Madeira A, et al. Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization. Genome Res. 2007;17:311-9 pubmed publisher
    b>Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis...
  43. Yin G, Qin M, Liu X, Suo J, Suo X. Expression of Toxoplasma gondii dense granule protein7 (GRA7) in Eimeria tenella. Parasitol Res. 2013;112:2105-9 pubmed publisher
    ..Until now, limited information is available concerning the characterization of GRA proteins in Eimeria. Eimeria tenella and Toxoplasma gondii are apicomplexan protozoa and share many similarities in biology and genomics...
  44. Pinard van der Laan M, Bed Hom B, Coville J, Pitel F, Feve K, Leroux S, et al. Microsatellite mapping of QTLs affecting resistance to coccidiosis (Eimeria tenella) in a Fayoumi x White Leghorn cross. BMC Genomics. 2009;10:31 pubmed publisher
    ..The purpose of this work was to detect for the first time QTL for disease resistance traits to Eimeria tenella in chicken by performing a genome scan in an F2 cross issued from a resistant Fayoumi line and a susceptible ..
  45. Huang X, Zou J, Xu H, Ding Y, Yin G, Liu X, et al. Transgenic Eimeria tenella expressing enhanced yellow fluorescent protein targeted to different cellular compartments stimulated dichotomic immune responses in chickens. J Immunol. 2011;187:3595-602 pubmed publisher
    b>Eimeria tenella, one of the seven species of chicken coccidia, elicits protective immunity against challenge infection with both homologous and heterologous strains. We endeavor to use recombinant E...
  46. Bromley E, Leeds N, Clark J, McGregor E, Ward M, Dunn M, et al. Defining the protein repertoire of microneme secretory organelles in the apicomplexan parasite Eimeria tenella. Proteomics. 2003;3:1553-61 pubmed
    ..Purified microneme proteins from Eimeria tenella sporozoites were excised from two-dimensional (2-D) gels and analyzed using matrix-assisted laser desorption/..
  47. Pinney J, Shirley M, McConkey G, Westhead D. metaSHARK: software for automated metabolic network prediction from DNA sequence and its application to the genomes of Plasmodium falciparum and Eimeria tenella. Nucleic Acids Res. 2005;33:1399-409 pubmed
    ..We then apply SHARKhunt to the unannotated genome sequences of the coccidian parasite Eimeria tenella and observe that, at an E-value cut-off of 10(-20), our software makes 142 additional assertions of enzymatic ..
  48. Garcia J, Guimarães J, Headley S, Bogado A, Bugni F, Ramalho D, et al. Eimeria tenella: utilization of a nasal vaccine with sporozoite antigens incorporated into Iscom as protection for broiler breeders against a homologous challenge. Exp Parasitol. 2008;120:185-90 pubmed publisher
    The aim of this study was to evaluate a nasal vaccine using antigens derived from sporozoites of Eimeria tenella incorporated into Iscom to protect broiler chicks...
  49. Periz J, Gill A, Hunt L, Brown P, Tomley F. The microneme proteins EtMIC4 and EtMIC5 of Eimeria tenella form a novel, ultra-high molecular mass protein complex that binds target host cells. J Biol Chem. 2007;282:16891-8 pubmed
    b>Eimeria tenella, in common with other parasitic protozoa of the phylum Apicomplexa, invades host cells using an actinomyosin-powered "glideosome" complex and requires the secretion of adhesive proteins from the microneme ..
  50. Zhou B, Wang H, Zhao Z, Liu M, Yan W, Zhao J, et al. A novel serine/threonine protein phosphatase type 5 from second-generation merozoite of Eimeria tenella is associated with diclazuril-induced apoptosis. Parasitol Res. 2013;112:1771-80 pubmed publisher
    ..To assess the roles of the serine/threonine protein phosphatase type 5 of second-generation merozoites in Eimeria tenella (EtPP5) in the anticoccidial activity of diclazuril against chicken coccidiosis, EtPP5 was cloned using ..
  51. Qi N, Wang Y, Liao S, Wu C, Lv M, Li J, et al. Partial protective of chickens against Eimeria tenella challenge with recombinant EtMIC-1 antigen. Parasitol Res. 2013;112:2281-7 pubmed publisher
    b>Eimeria tenella microneme protein 1 (EtMIC-1) is highly conserved with TgMIC-2, which is involved in parasite binding specifically to host cells. Little is known about the immune responses and protective efficacy against E...
  52. Hosse R, Krucken J, Bierbaum S, Greif G, Wunderlich F. Eimeria tenella: genomic organization and expression of an 89kDa cyclophilin. Exp Parasitol. 2008;118:275-9 pubmed
    Though parasite cyclophilins are promising new drug targets, Eimeria tenella cyclophilins have not been characterized yet. Here, we describe an 89kDa cyclophilin, designated EtCYP89...
  53. Lu J, Muench S, Allary M, Campbell S, Roberts C, Mui E, et al. Type I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structure. Parasitology. 2007;134:1949-62 pubmed
    ..Recent results show that Eimeria tenella harbours an apicoplast organelle, and that a key biosynthetic enzyme, enoyl reductase, is located in this ..
  54. Kinnaird J, Bumstead J, Mann D, Ryan R, Shirley M, Shiels B, et al. EtCRK2, a cyclin-dependent kinase gene expressed during the sexual and asexual phases of the Eimeria tenella life cycle. Int J Parasitol. 2004;34:683-92 pubmed
    EtCRK2, a cyclin-dependent kinase from the coccidian parasite, Eimeria tenella is closely related to eukaryotic cyclin-dependent kinases that regulate progression of the cell cycle and to several cyclin-dependent kinases identified in ..
  55. Wan K, Chong S, Ng S, Shirley M, Tomley F, Jangi M. A survey of genes in Eimeria tenella merozoites by EST sequencing. Int J Parasitol. 1999;29:1885-92 pubmed
    ..from a merozoite cDNA library, was initiated as an approach to generate a larger pool of gene information on Eimeria tenella. Of the ESTs, 47...
  56. Hao L, Liu X, Zhou X, Li J, Suo X. Transient transfection of Eimeria tenella using yellow or red fluorescent protein as a marker. Mol Biochem Parasitol. 2007;153:213-5 pubmed
  57. Tabarés E, Ferguson D, Clark J, Soon P, Wan K, Tomley F. Eimeria tenella sporozoites and merozoites differentially express glycosylphosphatidylinositol-anchored variant surface proteins. Mol Biochem Parasitol. 2004;135:123-32 pubmed
    Little is known about glycosylphosphatidylinositol (GPI)-linked surface proteins in the coccidian parasite Eimeria tenella. Examination of 28,550 EST sequences from the sporozoite and second merozoite developmental stages of the parasite ..
  58. Hafeez M, Akhtar M, Ayaz M. Some observations on the adaptation of Eimeria tenella (local isolates) sporozoites on chicken embryos through chorioallantoic membrane. J Vet Sci. 2006;7:59-61 pubmed
    ..In some cases, cluster of small mature and immature relatively large bodies were seen in increasing numbers on 5-6 days post inoculation...
  59. Ng S, Sanusi Jangi M, Shirley M, Tomley F, Wan K. Comparative EST analyses provide insights into gene expression in two asexual developmental stages of Eimeria tenella. Exp Parasitol. 2002;101:168-73 pubmed
    The protozoan parasite Eimeria tenella has a complex life cycle that includes two major asexual developmental stages, the merozoite and the sporozoite...
  60. Zhang D, Xu H, Sun B, Li J, Zhou Q, Zhang H, et al. Adjuvant effect of ginsenoside-based nanoparticles (ginsomes) on the recombinant vaccine against Eimeria tenella in chickens. Parasitol Res. 2012;110:2445-53 pubmed publisher
    ..Three-day-old chickens were vaccinated with Eimeria tenella recombinant profilin antigen (10, 50, and 100 ?g per chicken) with or without 50 ?g ginsomes per chicken...
  61. Schubert U, Fuchs J, Zimmermann J, Jahn D, Zoufal K. Extracellular calcium deficiency and ryanodine inhibit Eimeria tenella sporozoite invasion in vitro. Parasitol Res. 2005;97:59-62 pubmed
    An in vitro assay system with Eimeria tenella sporozoites was used to study the effects of extracellular calcium and active agents affecting the invasion of parasites into host cells...
  62. De Pablos L, dos Santos M, Montero E, Garcia Granados A, Parra A, Osuna A. Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens. Parasitol Res. 2010;107:601-4 pubmed publisher
    ..as a new natural coccidiostatic product against Eimeria tenella. Its action in infected animals has been compared with animals treated with sodium salinomycin...
  63. de Venevelles P, Chich J, Faigle W, Loew D, Labbé M, Girard Misguich F, et al. Towards a reference map of Eimeria tenella sporozoite proteins by two-dimensional electrophoresis and mass spectrometry. Int J Parasitol. 2004;34:1321-31 pubmed
    b>Eimeria tenella is a parasite of great importance as a disease causing agent in the poultry industry. Until recently, biological studies have focused on specific proteins, some of which play an important role in the parasite life cycle...
  64. Tierney J, Gowing H, van Sinderen D, Flynn S, Stanley L, McHardy N, et al. In vitro inhibition of Eimeria tenella invasion by indigenous chicken Lactobacillus species. Vet Parasitol. 2004;122:171-82 pubmed
    ..of indigenous chicken Lactobacillus species isolates from different parts of the gastrointestinal tract on Eimeria tenella invasion in vitro and to characterise the nature of inhibition, if any...
  65. Jeurissen S, Janse E, Vermeulen A, Vervelde L. Eimeria tenella infections in chickens: aspects of host-parasite: interaction. Vet Immunol Immunopathol. 1996;54:231-8 pubmed
    ..Second, the sporozoite seems to be the most important parasite stage for immunity, and third, cytotoxic T cells are necessary to inhibit parasites...
  66. Shi T, Liu X, Hao L, Li J, Gh A, Abdille M, et al. Transfected Eimeria tenella could complete its endogenous development in vitro. J Parasitol. 2008;94:978-80 pubmed publisher
    ..We investigated the ability of Eimeria tenella to express an exogenous gene in vitro...
  67. Lal K, Bromley E, Oakes R, Prieto J, Sanderson S, Kurian D, et al. Proteomic comparison of four Eimeria tenella life-cycle stages: unsporulated oocyst, sporulated oocyst, sporozoite and second-generation merozoite. Proteomics. 2009;9:4566-76 pubmed publisher
    We report the proteomes of four life-cycle stages of the Apicomplexan parasite Eimeria tenella. A total of 1868 proteins were identified, with 630, 699, 845 and 1532 found in early oocysts (unsporulated), late oocysts (sporulated), ..
  68. Tomley F. Techniques for isolation and characterization of apical organelles from Eimeria tenella sporozoites. Methods. 1997;13:171-6 pubmed
    ..Large numbers of surface-sterilized oocysts of Eimeria tenella, an apicomplexan coccidian of the chicken, can be routinely obtained from the animal host, and invasive ..
  69. del Cacho E, Gallego M, Francesch M, Quilez J, Sanchez Acedo C. Effect of artemisinin on oocyst wall formation and sporulation during Eimeria tenella infection. Parasitol Int. 2010;59:506-11 pubmed publisher
    ..Commercial artemisinin was administered at 10 and 17 ppm in food and tested against infection with Eimeria tenella. A battery trial to quantify the effect of artemisinin on the reproductive and infective capabilities of E...
  70. Fetterer R, Miska K, Barfield R. Partial purification and characterization of an aminopeptidase from Eimeria tenella. J Parasitol. 2005;91:1280-6 pubmed
    Our previous investigation demonstrated the expression in Eimeria tenella sporulated oocysts of an aminopeptidase (AP) with strong homology to AP N...
  71. Labb M, P roval M, Bourdieu C, Girard Misguich F, P ry P. Eimeria tenella enolase and pyruvate kinase: a likely role in glycolysis and in others functions. Int J Parasitol. 2006;36:1443-52 pubmed publisher
    ..glycolytic enzymes were cloned from a cDNA library constructed from the schizont stage of the avian parasite Eimeria tenella. Enolase and pyruvate kinase cDNA were fully sequenced and compared with sequences of enzymes from other ..
  72. Daszak P. Zoite migration during infection: parasite adaptation to host defences. Parasitol Today. 1999;15:67-72 pubmed
    The apicomplexan parasite Eimeria tenella has evolved a number of strategies for migration into different compartments of the intestinal tissue during its life cycle...
  73. Subramanian B, Sriraman R, Rao N, Raghul J, Thiagarajan D, Srinivasan V. Cloning, expression and evaluation of the efficacy of a recombinant Eimeria tenella sporozoite antigen in birds. Vaccine. 2008;26:3489-96 pubmed publisher
    ..Here we describe cloning and expression of microneme-1 protein of Eimeria tenella, obtained from an outbreak sample from India...
  74. Laurent F, Mancassola R, Lacroix S, Menezes R, Naciri M. Analysis of chicken mucosal immune response to Eimeria tenella and Eimeria maxima infection by quantitative reverse transcription-PCR. Infect Immun. 2001;69:2527-34 pubmed
  75. Shah M, Xu L, Yan R, Song X, Li X. Cross immunity of DNA vaccine pVAX1-cSZ2-IL-2 to Eimeria tenella, E. necatrix and E. maxima. Exp Parasitol. 2010;124:330-3 pubmed publisher
    ..Groups 2 and 6 were inoculated with Eimeria tenella, groups 3 and 7 with Eimerianecatrix, groups 4 and 8 with Eimeria acervulina and groups 5 and 9 with Eimeria ..
  76. Zhou B, Wang H, Xue F, Wang X, Fei C, Wang M, et al. Effects of diclazuril on apoptosis and mitochondrial transmembrane potential in second-generation merozoites of Eimeria tenella. Vet Parasitol. 2010;168:217-22 pubmed publisher
    Diclazuril, a benzeneacetonitrile anticoccidial agent, has potent activity against various stages of Eimeria tenella (E. tenella). To study the effects of diclazuril on E...
  77. Yan W, Liu X, Shi T, Hao L, Tomley F, Suo X. Stable transfection of Eimeria tenella: constitutive expression of the YFP-YFP molecule throughout the life cycle. Int J Parasitol. 2009;39:109-17 pubmed publisher
    The obligate intracellular apicomplexan parasite Eimeria tenella, one of seven species of Eimeria that infect chickens, elicits protective cell-mediated immunity against challenge infection. For this reason, recombinant E...
  78. Allocco J, Nare B, Myers R, Feiglin M, Schmatz D, Profous Juchelka H. Nitrophenide (Megasul) blocks Eimeria tenella development by inhibiting the mannitol cycle enzyme mannitol-1-phosphate dehydrogenase. J Parasitol. 2001;87:1441-8 pubmed
    Unsporulated oocysts of the protozoan parasite Eimeria tenella contain high levels of mannitol, which is thought to be the principal energy source for the process of sporulation...
  79. Salowe S, Wiltsie J, Liberator P, Donald R. The role of a parasite-specific allosteric site in the distinctive activation behavior of Eimeria tenella cGMP-dependent protein kinase. Biochemistry. 2002;41:4385-91 pubmed
    ..protein kinase (PKG) was recently identified as an anticoccidial target for the apicomplexan parasite Eimeria tenella [Gurnett, A., Liberator, P. A., Dulski, P., Salowe, S., Donald, R. G. K., Anderson, J., Wiltsie, J., Diaz, C...
  80. Lee S, Lillehoj H, Jang S, Lee K, Bravo D, Lillehoj E. Effects of dietary supplementation with phytonutrients on vaccine-stimulated immunity against infection with Eimeria tenella. Vet Parasitol. 2011;181:97-105 pubmed publisher
    ..with VAC- or MC-supplemented diets, immunized with profilin, and orally challenged with virulent oocysts of Eimeria tenella. Immunity against infection was evaluated by body weight, fecal oocyst shedding, profilin antibody levels, ..
  81. Berezin V, Bogoyavlenskyi A, Khudiakova S, Alexuk P, Omirtaeva E, Zaitceva I, et al. Immunostimulatory complexes containing Eimeria tenella antigens and low toxicity plant saponins induce antibody response and provide protection from challenge in broiler chickens. Vet Parasitol. 2010;167:28-35 pubmed publisher
    ..In the current study, both the route of administration and the antigen concentration of ISCOMs, containing Eimeria tenella antigens and saponins from native plants, were evaluated in their ability to stimulate humoral immunity and ..
  82. Liu X, Zou J, Yin G, Su H, Huang X, Li J, et al. Development of transgenic lines of Eimeria tenella expressing M2e-enhanced yellow fluorescent protein (M2e-EYFP). Vet Parasitol. 2013;193:1-7 pubmed publisher
    ..maintains this property or not needs to be verified. In this study, two identical transgenic lines of Eimeria tenella were developed by virtue of single sporocyst isolation from a stably transfected population expressing fused ..
  83. Miyamoto T, Min W, Lillehoj H. Lymphocyte proliferation response during Eimeria tenella infection assessed by a new, reliable, nonradioactive colorimetric assay. Avian Dis. 2002;46:10-6 pubmed
    ..with WST-8 was highly reproducible and showed a significant increase in IL-2 production upon stimulation of Eimeria tenella-immune spleen cells with Con A. After E...
  84. Du A, Hu S, Wang S. Eimeria tenella: ginsenosides-enhanced immune response to the immunization with recombinant 5401 antigen in chickens. Exp Parasitol. 2005;111:191-7 pubmed
    Three-day-old specific-pathogen-free chickens were subcutaneously immunized with Eimeria tenella recombinant 5401 antigen (100 microg per chicken) with (0.25, 0.5 or 1...
  85. Wiersma H, Galuska S, Tomley F, Sibley L, Liberator P, Donald R. A role for coccidian cGMP-dependent protein kinase in motility and invasion. Int J Parasitol. 2004;34:369-80 pubmed
    ..pyridine (compound 1), which effectively controls the proliferation of Eimeria tenella and Toxoplasma gondii parasites in animal models...
  86. del Cacho E, Gallego M, Lee S, Lillehoj H, Quilez J, Lillehoj E, et al. Induction of protective immunity against Eimeria tenella infection using antigen-loaded dendritic cells (DC) and DC-derived exosomes. Vaccine. 2011;29:3818-25 pubmed publisher
    ..In this study, we describe an alternative immunization strategy against Eimeria tenella infection using parasite antigen (Ag)-loaded dendritic cells (DCs), or their derived exosomes, in the absence ..
  87. Geriletu -, Xu L, Xurihua -, Li X. Vaccination of chickens with DNA vaccine expressing Eimeria tenella MZ5-7 against coccidiosis. Vet Parasitol. 2011;177:6-12 pubmed publisher
    A chimeric DNA vaccine co-expressing Eimeria tenella MZ5-7 and chicken IL-17 gene was constructed and its efficacy against E. tenella challenge was evaluated. The ORF of MZ5-7 from E...