oxidoreductases acting on ch nh2 group donors
Summary: Enzymes catalyzing the dehydrogenation of or oxidation of compounds containing primary amines.
Forneris F, Battaglioli E, Mattevi A, Binda C. New roles of flavoproteins in molecular cell biology: histone demethylase LSD1 and chromatin. FEBS J. 2009;276:4304-12 pubmed publisher
..LSD1 shares structural features with other flavin amine oxidases, including the overall fold of the amine oxidase domain region and details in the active site that are relevant for amine substrate oxidation. ..
Liu Y, Wu W, Lu Y, Lai Y, Hou W. Antioxidant and amine oxidase inhibitory activities of hydroxyurea. Biosci Biotechnol Biochem. 2010;74:1256-60 pubmed
..HU showed mixed-type, competitive-type, and competitive-type inhibition, respectively, with respect to substrates of MAO-A, MAO-B, and SSAO with apparent inhibition constants (Ki) of 19.46, 5.38, and 1.84 microM. ..