nitrate reductase

Summary

Summary: An enzyme that catalyzes the oxidation of nitrite to nitrate. It is a cytochrome protein that contains IRON and MOLYBDENUM.

Top Publications

  1. Dementin S, Arnoux P, Frangioni B, Grosse S, Leger C, Burlat B, et al. Access to the active site of periplasmic nitrate reductase: insights from site-directed mutagenesis and zinc inhibition studies. Biochemistry. 2007;46:9713-21 pubmed
    The periplasmic nitrate reductase (NapAB), a member of the DMSO reductase superfamily, catalyzes the first step of the denitrification process in bacteria...
  2. Coelho C, González P, Moura J, Moura I, Trincao J, João Romão M. The crystal structure of Cupriavidus necator nitrate reductase in oxidized and partially reduced states. J Mol Biol. 2011;408:932-48 pubmed publisher
    The periplasmic nitrate reductase (NapAB) from Cupriavidus necator is a heterodimeric protein that belongs to the dimethyl sulfoxide reductase family of mononuclear Mo-containing enzymes and catalyzes the reduction of nitrate to nitrite...
  3. Xiong J, Fu G, Yang Y, Zhu C, Tao L. Tungstate: is it really a specific nitrate reductase inhibitor in plant nitric oxide research?. J Exp Bot. 2012;63:33-41 pubmed publisher
    b>Nitrate reductase (NR) is an enzymatic source of nitric oxide (NO) in plants, and it needs Mo for the Mo-cofactor to be activated...
  4. Gilberthorpe N, Poole R. Nitric oxide homeostasis in Salmonella typhimurium: roles of respiratory nitrate reductase and flavohemoglobin. J Biol Chem. 2008;283:11146-54 pubmed publisher
    ..typhimurium. However, mutant cells lacking the membrane-bound nitrate reductase, NarGHI, and membranes derived from these cells are unable to produce NO, demonstrating that, in wild-type S...
  5. Durvasula K, Jantama K, Fischer K, Vega A, Koopman B, Svoronos S. Effect of periplasmic nitrate reductase on diauxic lag of Paracoccus pantotrophus. Biotechnol Prog. 2009;25:973-9 pubmed publisher
    Paracoccus pantotrophus expresses two nitrate reductases-membrane bound nitrate reductase (Nar) and periplasmic nitrate reductase (Nap)...
  6. Morrison K, Simmons S, Stapleton A. Loci controlling nitrate reductase activity in maize: ultraviolet-B signaling in aerial tissues increases nitrate reductase activity in leaf and root when responsive alleles are present. Physiol Plant. 2010;140:334-41 pubmed publisher
    ..b>Nitrate reductase enzyme activity is responsible for the reduction of nitrate to nitrite, and nitrate is the major form of ..
  7. Martin A, Panaiotov S, Portaels F, Hoffner S, Palomino J, Angeby K. The nitrate reductase assay for the rapid detection of isoniazid and rifampicin resistance in Mycobacterium tuberculosis: a systematic review and meta-analysis. J Antimicrob Chemother. 2008;62:56-64 pubmed publisher
    ..The nitrate reductase assay (NRA) has been proposed as a rapid method for the detection of resistance to rifampicin and isoniazid, ..
  8. Nilavongse A, Brondijk T, Overton T, Richardson D, Leach E, Cole J. The NapF protein of the Escherichia coli periplasmic nitrate reductase system: demonstration of a cytoplasmic location and interaction with the catalytic subunit, NapA. Microbiology. 2006;152:3227-37 pubmed publisher
    The periplasmic nitrate reductase of Escherichia coli is important during anaerobic growth in low-nitrate environments...
  9. Kemppainen M, Duplessis S, Martin F, Pardo A. RNA silencing in the model mycorrhizal fungus Laccaria bicolor: gene knock-down of nitrate reductase results in inhibition of symbiosis with Populus. Environ Microbiol. 2009;11:1878-96 pubmed publisher
    ..Promoter-directed expression of double-stranded RNA with a partial coding sequence of the Laccaria nitrate reductase gene resulted in fungal transgenic strains strongly affected in growth with nitrate as N source in a medium ..

More Information

Publications62

  1. Singh D, Kumar S. Nitrate reductase, arginine deaminase, urease and dehydrogenase activities in natural soil (ridges with forest) and in cotton soil after acetamiprid treatments. Chemosphere. 2008;71:412-8 pubmed
    ..e. natural, control and experimental fields were tested for different enzyme activities. Nitrate reductase, arginine deaminase, urease and dehydrogenase activities were high in natural soil in comparison to control ..
  2. Du S, Zhang Y, Lin X, Wang Y, Tang C. Regulation of nitrate reductase by nitric oxide in Chinese cabbage pakchoi (Brassica chinensis L.). Plant Cell Environ. 2008;31:195-204 pubmed
    b>Nitrate reductase (NR), a committed enzyme in nitrate assimilation, involves generation of nitric oxide (NO) in plants...
  3. Young E, Dring M, Savidge G, Birkett D, Berges J. Seasonal variations in nitrate reductase activity and internal N pools in intertidal brown algae are correlated with ambient nitrate concentrations. Plant Cell Environ. 2007;30:764-74 pubmed
    ..Internal NO(3) (-) storage, total N content and nitrate reductase activity (NRA) were most affected by ambient NO(3) (-), with highest values in winter, when ambient NO(3) (-)..
  4. Hirano T, Ito A, Berberich T, Terauchi R, Saitoh H. Virus-induced gene silencing of 14-3-3 genes abrogates dark repression of nitrate reductase activity in Nicotiana benthamiana. Mol Genet Genomics. 2007;278:125-33 pubmed
    In order to study the effect of repression of 14-3-3 genes on actual activity of the nitrate reductase (NR) in Nicotiana benthamiana leaves, Nb14-3-3a gene was silenced by virus-induced gene silencing (VIGS) method using potato virus X (..
  5. Lambeck I, Chi J, Krizowski S, Mueller S, Mehlmer N, Teige M, et al. Kinetic analysis of 14-3-3-inhibited Arabidopsis thaliana nitrate reductase. Biochemistry. 2010;49:8177-86 pubmed publisher
    Eukaryotic assimilatory nitrate reductase (NR) is a dimeric multidomain molybdo-heme-flavo protein that catalyzes the first and rate-limiting step in the nitrate assimilation of plants, algae, and fungi...
  6. Hofmann M. Density functional theory studies of model complexes for molybdenum-dependent nitrate reductase active sites. J Biol Inorg Chem. 2007;12:989-1001 pubmed
  7. Lanciano P, Savoyant A, Grimaldi S, Magalon A, Guigliarelli B, Bertrand P. New method for the spin quantitation of [4Fe-4S](+) clusters with S = (3)/(2). Application to the FS0 center of the NarGHI nitrate reductase from Escherichia coli. J Phys Chem B. 2007;111:13632-7 pubmed
    ..By applying this method to the g approximately 5 signals displayed by NarGHI nitrate reductase, we were able to determine all the parameters of the spin Hamiltonian of FS0 centers with S = 3/2 and to ..
  8. Lanciano P, Vergnes A, Grimaldi S, Guigliarelli B, Magalon A. Biogenesis of a respiratory complex is orchestrated by a single accessory protein. J Biol Chem. 2007;282:17468-74 pubmed
    ..The dissimilatory nitrate reductase of the bacterial anaerobic respiratory chain is a membrane-bound heterotrimeric complex nitrate reductase A (..
  9. Palmer K, Brown S, Whiteley M. Membrane-bound nitrate reductase is required for anaerobic growth in cystic fibrosis sputum. J Bacteriol. 2007;189:4449-55 pubmed
    ..aeruginosa growth anaerobically, and mutational analysis revealed that the membrane-bound nitrate reductase is essential for P. aeruginosa anaerobic growth in an in vitro CF sputum medium...
  10. Grahl S, Maillard J, Spronk C, Vuister G, Sargent F. Overlapping transport and chaperone-binding functions within a bacterial twin-arginine signal peptide. Mol Microbiol. 2012;83:1254-67 pubmed publisher
    ..processes have been unearthed that sequence these events, for example the signal peptide of the periplasmic nitrate reductase (NapA) is bound by a cytoplasmic chaperone (NapD) that is thought to regulate assembly and export of the ..
  11. Ize B, Coulthurst S, Hatzixanthis K, Caldelari I, Buchanan G, Barclay E, et al. Remnant signal peptides on non-exported enzymes: implications for the evolution of prokaryotic respiratory chains. Microbiology. 2009;155:3992-4004 pubmed publisher
    ..proteins are not exclusively located in the periplasm, however, with the major respiratory nitrate reductase (NarG) and the biotin sulfoxide reductase (BisC), for example, being located at the cytoplasmic side of the ..
  12. Khan A, Sarkar D. Identification of a respiratory-type nitrate reductase and its role for survival of Mycobacterium smegmatis in Wayne model. Microb Pathog. 2006;41:90-5 pubmed
    b>Nitrate reductase (NR) is found to be expressed in certain mycobacterium sp. whose link with the development of persistence is yet to be resolved...
  13. Sýkorová B, Kuresová G, Daskalova S, Trcková M, Hoyerova K, Raimanová I, et al. Senescence-induced ectopic expression of the A. tumefaciens ipt gene in wheat delays leaf senescence, increases cytokinin content, nitrate influx, and nitrate reductase activity, but does not affect grain yield. J Exp Bot. 2008;59:377-87 pubmed publisher
    ..There was a progressive increase in nitrate influx and nitrate reductase activity...
  14. Ani A, Daylop Y, Agbaji O, Idoko J. Drug susceptibility test of Mycobacterium tuberculosis by nitrate reductase assay. J Infect Dev Ctries. 2009;3:16-9 pubmed
    ..A simple and cost effective method, the nitrate reductase assay (NRA), was compared with the gold standard proportion (egg bases Lowenstein Jensen's [LJ]) method for ..
  15. Schinko T, Berger H, Lee W, Gallmetzer A, Pirker K, Pachlinger R, et al. Transcriptome analysis of nitrate assimilation in Aspergillus nidulans reveals connections to nitric oxide metabolism. Mol Microbiol. 2010;78:720-38 pubmed publisher
    ..Our analysis using membrane-permeable NO donors suggests that signalling for NirA activation only indirectly depends on the nitrate transporters NrtA (CrnA) and NrtB (CrnB). ..
  16. Rosales E, Iannone M, Groppa M, Benavides M. Nitric oxide inhibits nitrate reductase activity in wheat leaves. Plant Physiol Biochem. 2011;49:124-30 pubmed publisher
    b>Nitrate reductase (NR), a committed enzyme in nitrate assimilation, is involved in the generation of nitric oxide (NO) in plants...
  17. Jin C, Du S, Shamsi I, Luo B, Lin X. NO synthase-generated NO acts downstream of auxin in regulating Fe-deficiency-induced root branching that enhances Fe-deficiency tolerance in tomato plants. J Exp Bot. 2011;62:3875-84 pubmed publisher
    ..root branching was inhibited by the NO-synthase (NOS) inhibitor L-NAME, but was not affected by the nitrate reductase (NR) inhibitor NH(4)(+), tungstate or glycine...
  18. Simpson P, Codd R. Cold adaptation of the mononuclear molybdoenzyme periplasmic nitrate reductase from the Antarctic bacterium Shewanella gelidimarina. Biochem Biophys Res Commun. 2011;414:783-8 pubmed publisher
    The reduction of nitrate to nitrite is catalysed in bacteria by periplasmic nitrate reductase (Nap) which describes a system of variable protein subunits encoded by the nap operon...
  19. Jenkins B, Zehr J, Gibson A, Campbell L. Cyanobacterial assimilatory nitrate reductase gene diversity in coastal and oligotrophic marine environments. Environ Microbiol. 2006;8:2083-95 pubmed
    ..of nitrate-utilizing marine cyanobacteria, we developed PCR primers specific for cyanobacterial assimilatory nitrate reductase (narB) genes...
  20. Gordillo F, Aguilera J, Jimenez C. The response of nutrient assimilation and biochemical composition of Arctic seaweeds to a nutrient input in summer. J Exp Bot. 2006;57:2661-71 pubmed
    ..The enzymatic activities related to nutrient assimilation, external carbonic anhydrase (CAext, EC 4.2.1.1), nitrate reductase (NR, EC 1.6.6.1), and alkaline phosphatase (AP, EC 3.1.3...
  21. Nishimura T, Teramoto H, Toyoda K, Inui M, Yukawa H. Regulation of the nitrate reductase operon narKGHJI by the cAMP-dependent regulator GlxR in Corynebacterium glutamicum. Microbiology. 2011;157:21-8 pubmed publisher
    The Corynebacterium glutamicum anaerobic nitrate reductase operon narKGHJI is repressed by a transcriptional regulator, ArnR, under aerobic conditions...
  22. Ma Y, Guo C, Li H, Peng X. Low abundance of respiratory nitrate reductase is essential for Escherichia coli in resistance to aminoglycoside and cephalosporin. J Proteomics. 2013;87:78-88 pubmed publisher
    In the present study, we have characterized low abundance of NarG and NarH, two components of respiratory nitrate reductase (Nar), in streptomycin (SM)-, gentamicine (GEN)-, ceftazidime (CAZ)-, tetracycline (TET)- and nalidixic acid (NA)-..
  23. Wang B, Pierson L, Rensing C, Gunatilaka M, Kennedy C. NasT-mediated antitermination plays an essential role in the regulation of the assimilatory nitrate reductase operon in Azotobacter vinelandii. Appl Environ Microbiol. 2012;78:6558-67 pubmed publisher
    ..The results also support the hypothesis that NasT binds the promoter proximal hairpin of nasAB for its regulatory function, which contributes to the understanding of the regulatory mechanism of ANTAR-containing antiterminators...
  24. Giffin M, Raab R, Morganstern M, Sohaskey C. Mutational analysis of the respiratory nitrate transporter NarK2 of Mycobacterium tuberculosis. PLoS ONE. 2012;7:e45459 pubmed publisher
    Mycobacterium tuberculosis induces nitrate reductase activity in response to decreasing oxygen levels. This is due to regulation of both the transcription and the activity of the nitrate transporter NarK2...
  25. Lemus D, Montoro E, Echemendia M, Martin A, Portaels F, Palomino J. Nitrate reductase assay for detection of drug resistance in Mycobacterium tuberculosis: simple and inexpensive method for low-resource laboratories. J Med Microbiol. 2006;55:861-3 pubmed
    The nitrate reductase assay (NRA) was used as an alternative method for detection of resistance to the first-line antituberculous drugs isoniazid, rifampicin, ethambutol and streptomycin...
  26. Simpson P, Richardson D, Codd R. The periplasmic nitrate reductase in Shewanella: the resolution, distribution and functional implications of two NAP isoforms, NapEDABC and NapDAGHB. Microbiology. 2010;156:302-12 pubmed publisher
    In the bacterial periplasm, the reduction of nitrate to nitrite is catalysed by a periplasmic nitrate reductase (NAP) system, which is a species-dependent assembly of protein subunits encoded by the nap operon...
  27. Freschi L, Nievola C, Rodrigues M, Domingues D, Van Sluys M, Mercier H. Thermoperiod affects the diurnal cycle of nitrate reductase expression and activity in pineapple plants by modulating the endogenous levels of cytokinins. Physiol Plant. 2009;137:201-12 pubmed publisher
    b>Nitrate reductase (NR, EC 1.6.6.1) activity in higher plants is regulated by a variety of environmental factors and oscillates with a characteristic diurnal rhythm...
  28. Jepson B, Mohan S, Clarke T, Gates A, Cole J, Butler C, et al. Spectropotentiometric and structural analysis of the periplasmic nitrate reductase from Escherichia coli. J Biol Chem. 2007;282:6425-37 pubmed
    The Escherichia coli NapA (periplasmic nitrate reductase) contains a [4Fe-4S] cluster and a Mo-bis-molybdopterin guanine dinucleotide cofactor. The NapA holoenzyme associates with a di-heme c-type cytochrome redox partner (NapB)...
  29. Tian Q, Sun D, Zhao M, Zhang W. Inhibition of nitric oxide synthase (NOS) underlies aluminum-induced inhibition of root elongation in Hibiscus moscheutos. New Phytol. 2007;174:322-31 pubmed
    ..NO scavenger and inhibitors of NO synthase (NOS) and nitrate reductase had a similar inhibitory effect on root elongation...
  30. Fresneau C, Ghashghaie J, Cornic G. Drought effect on nitrate reductase and sucrose-phosphate synthase activities in wheat (Triticum durum L.): role of leaf internal CO2. J Exp Bot. 2007;58:2983-92 pubmed
    In order to study the impact of a decline of leaf internal CO(2) molar ratio on nitrate reductase (NR) and sucrose-phosphate synthase (SPS) activities, leaves of wheat (Triticum durum) were submitted to different treatments: slow or ..
  31. Jin C, Du S, Zhang Y, Lin X, Tang C. Differential regulatory role of nitric oxide in mediating nitrate reductase activity in roots of tomato (Solanum lycocarpum). Ann Bot. 2009;104:9-17 pubmed publisher
    Nitric oxide (NO) has been demonstrated to stimulate the activity of nitrate reductase (NR) in plant roots supplied with a low level of nitrate, and to affect proteins differently, depending on the ratio of NO to the level of protein...
  32. Shikama M, Silva R, Martins M, Giampaglia C, Oliveira R, Silva R, et al. Rapid detection of resistant tuberculosis by nitrate reductase assay performed in three settings in Brazil. J Antimicrob Chemother. 2009;64:794-6 pubmed publisher
    To evaluate nitrate reductase assay (NRA) efficacy for streptomycin, isoniazid, rifampicin and ethambutol susceptibility testing of Mycobacterium tuberculosis strains...
  33. Visalakshi P, Meharwal S, Myneedu V, Behera D. Evaluation of direct method of drug susceptibility testing of Mycobacterium tuberculosis to rifampicin and isoniazid by nitrate reductase assay in a national reference laboratory. Diagn Microbiol Infect Dis. 2010;66:148-52 pubmed publisher
    The aim of this study was to evaluate a simple, rapid, and inexpensive colorimetric nitrate reductase assay (NRA) for direct drug susceptibility testing (DST) of Mycobacterium tuberculosis against rifampicin (RIF) and isoniazid (INH)...
  34. Al Dahouk S, Loisel Meyer S, Scholz H, Tomaso H, Kersten M, Harder A, et al. Proteomic analysis of Brucella suis under oxygen deficiency reveals flexibility in adaptive expression of various pathways. Proteomics. 2009;9:3011-21 pubmed publisher
    ..This highly flexible respiration probably constitutes an advantage for the survival of Brucella under the restricted oxygenation conditions encountered within host tissue...
  35. Schinko T, Gallmetzer A, Amillis S, Strauss J. Pseudo-constitutivity of nitrate-responsive genes in nitrate reductase mutants. Fungal Genet Biol. 2013;54:34-41 pubmed publisher
    ..In all studied fungi and in plants, mutants lacking nitrate reductase (NR) activity express nitrate-metabolizing enzymes constitutively without the addition of inducer molecules...
  36. Young E, Berges J, Dring M. Physiological responses of intertidal marine brown algae to nitrogen deprivation and resupply of nitrate and ammonium. Physiol Plant. 2009;135:400-11 pubmed publisher
    ..Over 15 weeks of N deprivation, internal N and nitrate reductase activity (NRA) declined, but maximum quantum yield of PSII was unaffected in Fucus serratus and Fucus ..
  37. Stewart V, Bledsoe P, Chen L, Cai A. Catabolite repression control of napF (periplasmic nitrate reductase) operon expression in Escherichia coli K-12. J Bacteriol. 2009;191:996-1005 pubmed publisher
    ..Maximal expression of the napFDAGHBC operon encoding periplasmic nitrate reductase results from synergistic transcription activation by the Fnr and phospho-NarP proteins, acting in response ..
  38. Wang P, Du Y, Song C. Phosphorylation by MPK6: a conserved transcriptional modification mediates nitrate reductase activation and NO production?. Plant Signal Behav. 2011;6:889-91 pubmed
    b>Nitrate reductase is a central enzyme of nitrogen assimilation in plants...
  39. Van Ree K, Gehl B, Chehab E, Tsai Y, Braam J. Nitric oxide accumulation in Arabidopsis is independent of NOA1 in the presence of sucrose. Plant J. 2011;68:225-33 pubmed publisher
    ..We conclude that NOA1 has a primary role in chloroplast function and that its effects on the accumulation of nitric oxide are likely to be indirect. ..
  40. Rosales E, Iannone M, Groppa M, Benavides M. Polyamines modulate nitrate reductase activity in wheat leaves: involvement of nitric oxide. Amino Acids. 2012;42:857-65 pubmed publisher
    In the present work, the effect of polyamines (PAs) on nitrate reductase (NR) activity was studied in wheat leaves exposed to exogenously added PAs while assessing the nitric oxide (NO) involvement in the regulation of the enzyme ..
  41. Hofmann L, Straub S, Bischof K. Elevated CO2 levels affect the activity of nitrate reductase and carbonic anhydrase in the calcifying rhodophyte Corallina officinalis. J Exp Bot. 2013;64:899-908 pubmed publisher
    ..b>Nitrate reductase, the enzyme responsible for reduction of nitrate to nitrite, was stimulated by CO(2) and was highest in ..
  42. Malm S, Tiffert Y, Micklinghoff J, Schultze S, Joost I, Weber I, et al. The roles of the nitrate reductase NarGHJI, the nitrite reductase NirBD and the response regulator GlnR in nitrate assimilation of Mycobacterium tuberculosis. Microbiology. 2009;155:1332-9 pubmed publisher
    ..tuberculosis. Homologues to a narGHJI-encoded nitrate reductase and a nirBD-encoded nitrite reductase have been found on the chromosome of M. tuberculosis...
  43. Seligman K, Saviani E, Oliveira H, Pinto Maglio C, Salgado I. Floral transition and nitric oxide emission during flower development in Arabidopsis thaliana is affected in nitrate reductase-deficient plants. Plant Cell Physiol. 2008;49:1112-21 pubmed publisher
    The nitrate reductase (NR)-defective double mutant of Arabidopsis thaliana (nia1 nia2) has previously been shown to present a low endogenous content of NO in its leaves compared with the wild-type plants...
  44. Reddy K, Bellaloui N, Zablotowicz R. Glyphosate effect on shikimate, nitrate reductase activity, yield, and seed composition in corn. J Agric Food Chem. 2010;58:3646-50 pubmed publisher
    ..Visual plant injury, shikimate accumulation, nitrate reductase activity, leaf nitrogen, yield, and seed composition were evaluated...
  45. de Montaigu A, Sanz Luque E, Galvan A, Fernandez E. A soluble guanylate cyclase mediates negative signaling by ammonium on expression of nitrate reductase in Chlamydomonas. Plant Cell. 2010;22:1532-48 pubmed publisher
    ..assimilation in plants and related organisms is a highly regulated and conserved pathway in which the enzyme nitrate reductase (NR) occupies a central position...
  46. Correia C, Besson S, Brondino C, González P, Fauque G, Lampreia J, et al. Biochemical and spectroscopic characterization of the membrane-bound nitrate reductase from Marinobacter hydrocarbonoclasticus 617. J Biol Inorg Chem. 2008;13:1321-33 pubmed publisher
    Membrane-bound nitrate reductase from Marinobacter hydrocarbonoclasticus 617 can be solubilized in either of two ways that will ultimately determine the presence or absence of the small (Iota) subunit...
  47. Bai L, Yin W, Chen Y, Niu L, Sun Y, Zhao S, et al. A new strategy to produce a defensin: stable production of mutated NP-1 in nitrate reductase-deficient Chlorella ellipsoidea. PLoS ONE. 2013;8:e54966 pubmed publisher
    ..In this study, we developed a new strategy to produce defensin in nitrate reductase (NR)-deficient C. ellipsoidea (nrm-4)...
  48. Najmudin S, González P, Trincao J, Coelho C, Mukhopadhyay A, Cerqueira N, et al. Periplasmic nitrate reductase revisited: a sulfur atom completes the sixth coordination of the catalytic molybdenum. J Biol Inorg Chem. 2008;13:737-53 pubmed publisher
    b>Nitrate reductase from Desulfovibrio desulfuricans ATCC 27774 (DdNapA) is a monomeric protein of 80 kDa harboring a bis(molybdopterin guanine dinucleotide) active site and a [4Fe-4S] cluster...
  49. Eick M, Stöhr C. Denitrification by plant roots? New aspects of plant plasma membrane-bound nitrate reductase. Protoplasma. 2012;249:909-18 pubmed
    A specific form of plasma membrane-bound nitrate reductase in plants is restricted to roots...
  50. Zhang Y, Liu Z, Liu R, Wang L, Bi Y. Gibberellins negatively regulate light-induced nitrate reductase activity in Arabidopsis seedlings. J Plant Physiol. 2011;168:2161-8 pubmed publisher
    In the present study, the role of phytohormone gibberellins (GAs) on regulating the nitrate reductase (NR) activity was tested in Arabidopsis seedlings...
  51. Zhang M, Dong J, Jin H, Sun L, Xu M. Ultraviolet-B-induced flavonoid accumulation in Betula pendula leaves is dependent upon nitrate reductase-mediated nitric oxide signaling. Tree Physiol. 2011;31:798-807 pubmed publisher
    ..In order to evaluate the origin of UV-B-triggered NO generation, we examined the responses of nitrate reductase (NR) activity and the expression levels of NIA1 and NIA2 genes in leaves of Betula pendula Roth (silver ..
  52. Lu D, Dong J, Jin H, Sun L, Xu X, Zhou T, et al. Nitrate reductase-mediated nitric oxide generation is essential for fungal elicitor-induced camptothecin accumulation of Camptotheca acuminata suspension cell cultures. Appl Microbiol Biotechnol. 2011;90:1073-81 pubmed publisher
    ..To investigate the origin of elicitor-triggered NO, we examined nitrate reductase (NR) activities and the expression levels of NIA1 and NIA2 genes of Camptotheca acuminata cells treated with ..
  53. Devasia R, Blackman A, May C, Eden S, Smith T, Hooper N, et al. Fluoroquinolone resistance in Mycobacterium tuberculosis: an assessment of MGIT 960, MODS and nitrate reductase assay and fluoroquinolone cross-resistance. J Antimicrob Chemother. 2009;63:1173-8 pubmed publisher
    ..mycobacterial growth indicator tube (MGIT) 960, microscopic observation drug susceptibility (MODS) assay and nitrate reductase assay (NRA) compared with the gold standard agar proportion method (PM), and to determine whether there is ..