cytochrome p450 family 6


Summary: A cytochrome P450 enzyme family that occurs in insects. Its members function in the metabolism of XENOBIOTICS.

Top Publications

  1. Konorov E, Nikitin M, Mikhailov K, Lysenkov S, Belenky M, Chang P, et al. Genomic exaptation enables Lasius niger adaptation to urban environments. BMC Evol Biol. 2017;17:39 pubmed publisher
    ..niger pollutant resistance and polyphagy, while non-territorial and mobilization strategies allows more efficient exploitation of large but patchy food sources. ..
  2. Peng T, Chen X, Pan Y, Zheng Z, Wei X, Xi J, et al. Transcription factor aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator is involved in regulation of the xenobiotic tolerance-related cytochrome P450 CYP6DA2 in Aphis gossypii Glover. Insect Mol Biol. 2017;26:485-495 pubmed publisher
    ..Thus, these elements located in the promoter were responsible for CYP6DA2 transcription, and CYP6DA2 expression was regulated by the transcription factors AhR and ARNT. ..
  3. Wang R, Zhu Y, Deng L, Zhang H, Wang Q, Yin M, et al. Imidacloprid is hydroxylated by Laodelphax striatellus CYP6AY3v2. Insect Mol Biol. 2017;26:543-551 pubmed publisher
    ..The data provided direct evidence that CYP6AY3v2 is capable of hydroxylation of imidacloprid and conferring metabolic resistance in L. striatellus. ..
  4. Tang G, Yao J, Li D, He Y, Zhu Y, Zhang X, et al. Cytochrome P450 genes from the aquatic midge Chironomus tentans: Atrazine-induced up-regulation of CtCYP6EX3 enhanced the toxicity of chlorpyrifos. Chemosphere. 2017;186:68-77 pubmed publisher
    ..tentans larvae to chlorpyrifos alone and the binary mixture of atrazine and chlorpyrifos. However, further study would be necessary to validate our results by functional assays using heterologously expressed CtCYP6EX3 enzyme. ..