Summary: The region in the dorsal ECTODERM of a chordate embryo that gives rise to the future CENTRAL NERVOUS SYSTEM. Tissue in the neural plate is called the neuroectoderm, often used as a synonym of neural plate.
Marchak A, Grant P, Neilson K, Datta Majumdar H, Yaklichkin S, Johnson D, et al
. Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates. Dev Biol. 2017;429:213-224 pubmed publisher
..of Wbp2nl in the dorsal ectoderm reduced cranial placode and neural crest gene expression domains and expanded neural plate domains; knock-down in ventral ectoderm reduced epidermal gene expression...
Heavner W, Pevny L. Eye development and retinogenesis. Cold Spring Harb Perspect Biol. 2012;4: pubmed publisher
..This article describes how the eye primordium is specified in the anterior neural plate by four eye field transcription factors and how the optic vesicle becomes regionalized into three distinct ..
Kimura Yoshida C, Mochida K, Ellwanger K, Niehrs C, Matsuo I. Fate Specification of Neural Plate Border by Canonical Wnt Signaling and Grhl3 is Crucial for Neural Tube Closure. EBioMedicine. 2015;2:513-27 pubmed publisher
..NE lineages, we observed that uncommitted progenitor cells, expressing stem cell markers, are present in the neural plate border/neural fold prior to neural tube closure...
Steventon B, Martinez Arias A. Evo-engineering and the cellular and molecular origins of the vertebrate spinal cord. Dev Biol. 2017;432:3-13 pubmed publisher
..In the first, a posteriorly localized signalling source transforms previously anterior-specified neural plate into the spinal cord...
Baumholtz A, Simard A, Nikolopoulou E, Oosenbrug M, Collins M, Piontek A, et al
. Claudins are essential for cell shape changes and convergent extension movements during neural tube closure. Dev Biol. 2017;428:25-38 pubmed publisher
..individual cells are translated into large-scale morphogenetic movements to facilitate conversion of the flat neural plate into a closed tube...
Dong X, Li J, He L, Gu C, Jia W, Yue Y, et al
. Zebrafish Znfl1 proteins control the expression of hoxb1b gene in the posterior neuroectoderm by acting upstream of pou5f3 and sall4 genes. J Biol Chem. 2017;292:13045-13055 pubmed publisher
Schock E, Brugmann S. Neural crest cells utilize primary cilia to regulate ventral forebrain morphogenesis via Hedgehog-dependent regulation of oriented cell division. Dev Biol. 2017;431:168-178 pubmed publisher
..Together, these data suggest a novel, cilia-dependent mechanism for NCCs during forebrain development. ..
de Castro S, Hirst C, Savery D, Rolo A, Lickert H, Andersen B, et al
. Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues. Dev Biol. 2018;435:130-137 pubmed publisher
..Conditional knockout of Grhl3 in the neural plate and node-streak border has minimal effect on closure, suggesting that abnormal function of surface ectoderm, ..