embryonic structures

Summary

Summary: The anatomical parts that make up an organism in the early stages of development.

Top Publications

  1. Estella C, Rieckhof G, Calleja M, Morata G. The role of buttonhead and Sp1 in the development of the ventral imaginal discs of Drosophila. Development. 2003;130:5929-41 pubmed
    ..We propose that this property is a reflection of the initial function of the btd/Sp1 genes that consists of establishing the fate of the ventral disc primordia and determining their pattern and growth...
  2. Fuss B, Josten F, Feix M, Hoch M. Cell movements controlled by the Notch signalling cascade during foregut development in Drosophila. Development. 2004;131:1587-95 pubmed
    ..Our results provide a novel link between the Notch signalling pathway and cytoskeletal reorganisation controlling cell movement during the development of foregut-associated organs. ..
  3. Guo Q, Loomis C, Joyner A. Fate map of mouse ventral limb ectoderm and the apical ectodermal ridge. Dev Biol. 2003;264:166-78 pubmed
    ..These studies have uncovered new aspects of the cellular mechanisms involved in AER formation and in partitioning the ventral ectoderm in mouse limb. ..
  4. Shellard A, Mayor R. Chemotaxis during neural crest migration. Semin Cell Dev Biol. 2016;55:111-8 pubmed publisher
    ..that is used by many different cell types during development for tissue organisation and the formation of embryonic structures, as well as disease like cancer metastasis...
  5. Benetti R, Gonzalo S, Jaco I, Schotta G, Klatt P, Jenuwein T, et al. Suv4-20h deficiency results in telomere elongation and derepression of telomere recombination. J Cell Biol. 2007;178:925-36 pubmed
    ..These results demonstrate the importance of chromatin architecture in the maintenance of telomere length homeostasis and reveal a novel role for histone lysine methylation in controlling telomere recombination...
  6. Shimp K, Bhatnagar K, Bonar C, Smith T. Ontogeny of the nasopalatine duct in primates. Anat Rec A Discov Mol Cell Evol Biol. 2003;274:862-9 pubmed
    ..Observations of neonatal primates suggest that NPD patency may be relatively common at birth and could serve other purposes in addition to being an access route for VNO stimuli...
  7. Yaguchi S, Yaguchi J, Burke R. Specification of ectoderm restricts the size of the animal plate and patterns neurogenesis in sea urchin embryos. Development. 2006;133:2337-46 pubmed
    ..Like other metazoans, echinoderms appear to have a phase of neural development during which the specification of ectoderm restricts and patterns neurogenesis...
  8. Puangchit P, Ishigaki M, Yasui Y, Kajita M, Ritthiruangdej P, Ozaki Y. Non-staining visualization of embryogenesis and energy metabolism in medaka fish eggs using near-infrared spectroscopy and imaging. Analyst. 2017;142:4765-4772 pubmed publisher
    ..Detailed embryonic structures were clearly depicted in the NIR images using the data from the 6400-5500 cm-1 region in which ..
  9. Yan Y, Bian W, Xie Z, Cao X, Le Roux I, Guillemot F, et al. Stat3 signaling is present and active during development of the central nervous system and eye of vertebrates. Dev Dyn. 2004;231:248-57 pubmed
    ..These results demonstrate that the active Stat3 protein is present and might play a role during the development of the central nervous system and eye. ..

More Information

Publications98

  1. Dawid I. Organizing the vertebrate embryo--a balance of induction and competence. PLoS Biol. 2004;2:E127 pubmed
  2. Tchirikov M, Schlabritz Loutsevitch N, Hubbard G, Schröder H, Nathanielsz P. Structural evidence for mechanisms to redistribute hepatic and ductus venosus blood flows in nonhuman primate fetuses. Am J Obstet Gynecol. 2005;192:1146-52 pubmed
  3. Lee K, Fodor W, Machaty Z. Dynamics of lamin A/C in porcine embryos produced by nuclear transfer. Mol Reprod Dev. 2007;74:1221-7 pubmed
    ..The results also indicate that lamin A/C is present in the nuclear envelope of pig oocytes and early embryos and unlike in some other species, its presence after nuclear transfer is not an indicator of erroneous reprogramming. ..
  4. Wanderling S, Simen B, Ostrovsky O, Ahmed N, Vogen S, Gidalevitz T, et al. GRP94 is essential for mesoderm induction and muscle development because it regulates insulin-like growth factor secretion. Mol Biol Cell. 2007;18:3764-75 pubmed
    ..The data identify insulin-like growth factor II as one developmentally important protein whose production depends on the activity of GRP94. ..
  5. Xie Y, Skinner E, Landry C, Handley V, Schonmann V, Jacobs E, et al. Influence of the embryonic preplate on the organization of the cerebral cortex: a targeted ablation model. J Neurosci. 2002;22:8981-91 pubmed
  6. Blum M, Andre P, Muders K, Schweickert A, Fischer A, Bitzer E, et al. Ciliation and gene expression distinguish between node and posterior notochord in the mammalian embryo. Differentiation. 2007;75:133-46 pubmed
  7. Thanos S, Püttmann S, Naskar R, Rose K, Langkamp Flock M, Paulus W. Potential role of Pax-2 in retinal axon navigation through the chick optic nerve stalk and optic chiasm. J Neurobiol. 2004;59:8-23 pubmed
    ..These data suggest that balanced expression of Pax-2 results in the correct formation of the chick chiasm at early stages by imposing accurate pathfinding within the optic stalk and the midline. ..
  8. Ruel L, Rodriguez R, Gallet A, Lavenant Staccini L, Therond P. Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog. Nat Cell Biol. 2003;5:907-13 pubmed
    ..We propose that the association of the Cos2 protein complex with Smo at the plasma membrane controls the stability of the complex and allows Ci activation, eliciting its nuclear translocation. ..
  9. Chandrasekaran V, Beckendorf S. senseless is necessary for the survival of embryonic salivary glands in Drosophila. Development. 2003;130:4719-28 pubmed
    ..Furthermore, we show that in the salivary glands, sens acts as an anti-apoptotic protein by repressing reaper and possibly hid. ..
  10. Voiculescu O, Taillebourg E, Pujades C, Kress C, Buart S, Charnay P, et al. Hindbrain patterning: Krox20 couples segmentation and specification of regional identity. Development. 2001;128:4967-78 pubmed
  11. Maden M, Blentic A, Reijntjes S, Seguin S, Gale E, Graham A. Retinoic acid is required for specification of the ventral eye field and for Rathke's pouch in the avian embryo. Int J Dev Biol. 2007;51:191-200 pubmed
    ..We also describe another organ, Rathke's pouch which fails to develop in the absence of retinoic acid. We attribute this to the down-regulation of Bmp2, Shh and Fgf8 which are known to be involved in the induction of this structure. ..
  12. Matrone G, Mullins J, Tucker C, Denvir M. Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae. Cell Cycle. 2016;15:3060-3069 pubmed
    ..Subsequently, it affects somatic growth and development of a number of key embryonic structures including the brain, heart, eye and blood vessels...
  13. Zhao H, Kegg H, Grady S, Truong H, Robinson M, Baum M, et al. Role of fibroblast growth factor receptors 1 and 2 in the ureteric bud. Dev Biol. 2004;276:403-15 pubmed
    ..In conclusion, FGFR2, but not FGFR1, appears crucial for ureteric bud branching morphogenesis and stromal mesenchyme patterning. ..
  14. Hagiwara N, Yeh M, Liu A. Sox6 is required for normal fiber type differentiation of fetal skeletal muscle in mice. Dev Dyn. 2007;236:2062-76 pubmed
    ..Together, our results suggest that Sox6 plays a critical role in the fiber type differentiation of fetal skeletal muscle. ..
  15. Francis S, Goh K, Hodivala Dilke K, Bader B, Stark M, Davidson D, et al. Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. Arterioscler Thromb Vasc Biol. 2002;22:927-33 pubmed
    ..Thus, successful early vasculogenesis and angiogenesis require alpha5-FN interactions. ..
  16. Zhang P, Chebath J, Lonai P, Revel M. Enhancement of oligodendrocyte differentiation from murine embryonic stem cells by an activator of gp130 signaling. Stem Cells. 2004;22:344-54 pubmed
    ..We conclude that this cytokine can significantly enhance the derivation of oligodendrocytes from ES cells. ..
  17. Wei S, Escudero L, Yu F, Chang L, Chen L, Ho Y, et al. Echinoid is a component of adherens junctions that cooperates with DE-Cadherin to mediate cell adhesion. Dev Cell. 2005;8:493-504 pubmed
    ..Finally, cells lacking either Echinoid or DE-Cadherin accumulate a high density of the reciprocal protein, further suggesting that Echinoid and DE-Cadherin play similar and complementary roles in cell adhesion. ..
  18. Koza A, Csoknya M. Embryogenesis of GABAergic elements in the nervous system of Eisenia fetida (Annelida, Oligochaeta). Acta Biol Hung. 2004;55:323-33 pubmed
    ..During the next stages, more and more fibres connect to the both tracts. At hatching, the development of the central nervous system of Eisenia fetida is not completed, the process is continued during the postembryonic development. ..
  19. Oosterveen T, Niederreither K, Dolle P, Chambon P, Meijlink F, Deschamps J. Retinoids regulate the anterior expression boundaries of 5' Hoxb genes in posterior hindbrain. EMBO J. 2003;22:262-9 pubmed
    ..The RARE and surrounding sequences are found at homologous positions in the human, mouse and zebrafish genome, which supports an evolutionarily conserved regulatory function. ..
  20. Joo J, Lee Y, Munguba G, Park S, Taxter T, Elsagga M, et al. Role of Pinin in neural crest, dorsal dermis, and axial skeleton development and its involvement in the regulation of Tcf/Lef activity in mice. Dev Dyn. 2007;236:2147-58 pubmed
    ..Taken together, the data suggest that Pnn plays important roles during mouse development through its involvement in regulation of Tcf/Lef activity...
  21. Noble B, Babiuk R, Clugston R, Underhill T, Sun H, Kawaguchi R, et al. Mechanisms of action of the congenital diaphragmatic hernia-inducing teratogen nitrofen. Am J Physiol Lung Cell Mol Physiol. 2007;293:L1079-87 pubmed
    ..Retinoid signaling perturbations do not appear to involve oxidative effects of nitrofen. Any substantial roles of nitrofen-induced perturbations of thyroid hormone signaling or receptor function are not supported. ..
  22. Koide T, Hayata T, Cho K. Negative regulation of Hedgehog signaling by the cholesterogenic enzyme 7-dehydrocholesterol reductase. Development. 2006;133:2395-405 pubmed
  23. Chan J, Mably J, Serluca F, Chen J, Goldstein N, Thomas M, et al. Morphogenesis of prechordal plate and notochord requires intact Eph/ephrin B signaling. Dev Biol. 2001;234:470-82 pubmed
    ..Our observations suggest Eph/ephrin B signaling plays an essential role in regulating cell movements during gastrulation. ..
  24. Callejo A, Torroja C, Quijada L, Guerrero I. Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix. Development. 2006;133:471-83 pubmed
    ..All these data show that the interaction of lipid-modified Hh with HSPG is important both for precise Hh spreading through the epithelium surface and for correct Hh reception. ..
  25. Tsukamoto N, Itoi M, Nishikawa M, Amagai T. Lack of Delta like 1 and 4 expressions in nude thymus anlages. Cell Immunol. 2005;234:77-80 pubmed
    ..In contrast, epithelial cells of the nude thymus anlages express neither Dll1 nor Dll4. These results indicate that expressions of Dll1 and Dll4 in thymic epithelial cells are regulated by Foxn1 transcriptional factor. ..
  26. Gibert Y, Gajewski A, Meyer A, Begemann G. Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling. Development. 2006;133:2649-59 pubmed
    ..Thus, RA signaling from flanking somites plays a dual early role in the condensing limb bud mesenchyme. ..
  27. Bornemann D, Duncan J, Staatz W, Selleck S, Warrior R. Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways. Development. 2004;131:1927-38 pubmed
    ..Our results may contribute to understanding the biological basis of hereditary multiple exostoses (HME), a disease associated with bone overgrowth that results from mutations in EXT1 and EXT2, the human orthologs of ttv and sotv. ..
  28. Paraskevas G, Koutsouflianiotis K, Iliou K. The first descriptions of various anatomical structures and embryological remnants of the heart: A systematic overview. Int J Cardiol. 2017;227:674-690 pubmed publisher
    ..The evolution of the awareness as regards the various anatomical and embryonic structures of the heart began from Greek medico-philosophers, such as Hippocrates, Herophilus, Erasistratus and Galen, ..
  29. Ko M. Embryogenomics: developmental biology meets genomics. Trends Biotechnol. 2001;19:511-8 pubmed
    ..This article discusses these new approaches and their applications to mammalian developmental biology...
  30. Magnusdottir E, Kalachikov S, Mizukoshi K, Savitsky D, Ishida Yamamoto A, Panteleyev A, et al. Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1. Proc Natl Acad Sci U S A. 2007;104:14988-93 pubmed
    ..These studies provide insight into cornification, identifying transcriptional regulatory circuitry and indicating the importance of blocking osmotic homeostasis...
  31. Wang Z, Mann R. Requirement for two nearly identical TGIF-related homeobox genes in Drosophila spermatogenesis. Development. 2003;130:2853-65 pubmed
  32. Ghiglione C, Amundadottir L, Andresdottir M, Bilder D, Diamonti J, Noselli S, et al. Mechanism of inhibition of the Drosophila and mammalian EGF receptors by the transmembrane protein Kekkon 1. Development. 2003;130:4483-93 pubmed
  33. Hojilla C, Kim I, Kassiri Z, Fata J, Fang H, Khokha R. Metalloproteinase axes increase beta-catenin signaling in primary mouse mammary epithelial cells lacking TIMP3. J Cell Sci. 2007;120:1050-60 pubmed
    ..Recombinant TIMP1, TIMP3 and TIMP4 inhibited ductal elongation whereas TIMP2 promoted this process...
  34. Pantalacci S, Tapon N, Leopold P. The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. Nat Cell Biol. 2003;5:921-7 pubmed
    ..Thus, Hpo may promote apoptosis by reducing cellular amounts of DIAP1. In addition, we show that Sav is an unstable protein that is stabilized by Hpo. We propose that Hpo and Sav function together to restrict tissue growth in vivo...
  35. Kim W, Kim H, Ahn D, Kim M, Park H. Timetable for intestinal rotation in staged human embryos and fetuses. Birth Defects Res A Clin Mol Teratol. 2003;67:941-5 pubmed
    ..The existing data on intestinal rotation during human development are contradictory regarding the timing of major events, and as such an exact timetable for rotation of the intestine in humans is not yet available...
  36. Basch M, GARCIA CASTRO M, Bronner Fraser M. Molecular mechanisms of neural crest induction. Birth Defects Res C Embryo Today. 2004;72:109-23 pubmed
  37. Bras Pereira C, Bessa J, Casares F. Odd-skipped genes specify the signaling center that triggers retinogenesis in Drosophila. Development. 2006;133:4145-9 pubmed
    ..The fly Wnt1 homologue wingless represses the odd-skipped genes drm and odd along the anterior margin and, in this manner, spatially restricts the extent of retinal differentiation within the eye field...
  38. Afonso N, Catala M. Sonic hedgehog and retinoic acid are not sufficient to induce motoneuron generation in the avian caudal neural tube. Dev Biol. 2005;279:356-67 pubmed
    ..Together, these data indicate that the rostral environment contains a signal different from both SHH and Retinoic Acid that acts on MN differentiation...
  39. Norris D. Breaking the left-right axis: do nodal parcels pass a signal to the left?. Bioessays. 2005;27:991-4 pubmed
    ..They describe small membrane-bound particles, which they term nodal vesicular parcels (NVPs), that are carried to the left side of the node. In the paper, they argue how signals carried within these parcels may break L-R symmetry...
  40. Bosch M, Serras F, Martin Blanco E, Baguna J. JNK signaling pathway required for wound healing in regenerating Drosophila wing imaginal discs. Dev Biol. 2005;280:73-86 pubmed
    ..Differences with such processes are also highlighted...
  41. Potter C, Huang H, Xu T. Drosophila Tsc1 functions with Tsc2 to antagonize insulin signaling in regulating cell growth, cell proliferation, and organ size. Cell. 2001;105:357-68 pubmed
    ..Genetic epistasis data are consistent with a model that Tsc1 and Tsc2 function together in the insulin signaling pathway...
  42. Woda J, Pastagia J, Mercola M, Artinger K. Dlx proteins position the neural plate border and determine adjacent cell fates. Development. 2003;130:331-42 pubmed
    ..We propose that Dlx proteins regulate intercellular signaling across the interface between neural and non-neural ectoderm that is critical for inducing and patterning adjacent cell fates...
  43. Etournay R, Zwaenepoel I, Perfettini I, Legrain P, Petit C, El Amraoui A. Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions. J Cell Sci. 2007;120:2838-50 pubmed
  44. Veltmaat J, Mailleux A, Thiery J, Bellusci S. Mouse embryonic mammogenesis as a model for the molecular regulation of pattern formation. Differentiation. 2003;71:1-17 pubmed
    ..For future investigations in the field, such a unique molecular identity of each mammary rudiment should be of critical concern...
  45. Niwa R, Nagata Ohashi K, Takeichi M, Mizuno K, Uemura T. Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell. 2002;108:233-46 pubmed
    ..Furthermore, SSH and the hSSHs dephosphorylated P cofilin in cultured cells and in cell-free assays. Our results strongly suggest that the SSH family plays a pivotal role in actin dynamics by reactivating ADF/cofilin in vivo...
  46. Cheung N, Peng Z, Chen M, Moore P, Whiteman M. Hydrogen sulfide induced neuronal death occurs via glutamate receptor and is associated with calpain activation and lysosomal rupture in mouse primary cortical neurons. Neuropharmacology. 2007;53:505-14 pubmed
    ..This study provides novel insights into cell death observed in neurodegenerative diseases involving glutamate receptor activation and perturbed H(2)S synthesis...
  47. Herzog W, Sonntag C, von der Hardt S, Roehl H, Varga Z, Hammerschmidt M. Fgf3 signaling from the ventral diencephalon is required for early specification and subsequent survival of the zebrafish adenohypophysis. Development. 2004;131:3681-92 pubmed
    ..This early specification seems to be essential for the subsequent survival of pituitary cells, but not for pituitary morphogenesis or pituitary cell proliferation...
  48. Lai E, Deblandre G, Kintner C, Rubin G. Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta. Dev Cell. 2001;1:783-94 pubmed
    ..Collectively, our data indicate that Neur is a ubiquitin ligase that positively regulates the N pathway by promoting the endocytosis and degradation of Dl...
  49. Webb D, Asmussen H, Murase S, Horwitz A. Cell migration in slice cultures. Methods Cell Biol. 2002;69:341-58 pubmed
  50. Weisblat D. Asymmetric cell divisions in the early embryo of the leech Helobdella robusta. Prog Mol Subcell Biol. 2007;45:79-95 pubmed
  51. Grange G, Tantau J, Pannier E, Aubry M, Viot G, Fallet Bianco C, et al. Prenatal diagnosis of fetal tail and postabortum anatomical description. Ultrasound Obstet Gynecol. 2001;18:531-3 pubmed
    ..The appendage was located under and behind the last sacral vertebra suggesting a true vestigial tail with a delayed process of regression...
  52. Duncan S. Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis. Biochem Soc Trans. 2005;33:1534-6 pubmed
    ..Here, we describe the usefulness and efficacy of this approach using GATA factors as an example...
  53. McLarren K, Litsiou A, Streit A. DLX5 positions the neural crest and preplacode region at the border of the neural plate. Dev Biol. 2003;259:34-47 pubmed
    ..We propose that patterning of the embryonic ectoderm is a multistep process that sequentially subdivides the ectoderm into regions with defined cell fates...
  54. Moore R, Larue L. Cell surface molecules and truncal neural crest ontogeny: a perspective. Birth Defects Res C Embryo Today. 2004;72:140-50 pubmed
    ..Here, we review some of the molecules present in this location and how they influence the fate of the neural crest and generate disease...
  55. Wu M, Massaeli H, Durston M, Mesaeli N. Differential expression and activity of matrix metalloproteinase-2 and -9 in the calreticulin deficient cells. Matrix Biol. 2007;26:463-72 pubmed
    ..Furthermore, PI3 kinase inhibitor decreased the expression of both the MMP-2 and MMP-9. This study is the first report on the role of calreticulin in regulating MMP activity...
  56. zur Lage P, Prentice D, Holohan E, Jarman A. The Drosophila proneural gene amos promotes olfactory sensillum formation and suppresses bristle formation. Development. 2003;130:4683-93 pubmed
    ..This supports a model of inhibitory interactions between proneural genes, whereby ato-like genes (amos and ato) must suppress sensory bristle fate as well as promote alternative sense organ subtypes...
  57. Gaillard F. Heterotopic, not homotopic, fetal occipital allografts in adult hosts project to visual-related extracortical targets. Restor Neurol Neurosci. 2007;25:161-75 pubmed
    ..2004). The present study was undertaken to examine in detail whether this pattern is specific to graft location...
  58. Matsushita S, Ishii Y, Scotting P, Kuroiwa A, Yasugi S. Pre-gut endoderm of chick embryos is regionalized by 1.5 days of development. Dev Dyn. 2002;223:33-47 pubmed
    ..Thus, each part of the pre-gut endoderm appears to be already regionally committed to some extent, in accordance with its fate by 1.5 days of development...
  59. Warner D, Bhattacherjee V, Yin X, Singh S, Mukhopadhyay P, Pisano M, et al. Functional interaction between Smad, CREB binding protein, and p68 RNA helicase. Biochem Biophys Res Commun. 2004;324:70-6 pubmed
    ..This offers a means of enhancing TGFbeta-mediated cellular responses in developing orofacial tissue...
  60. Schlosser G. Induction and specification of cranial placodes. Dev Biol. 2006;294:303-51 pubmed
    ..Integrating current data, new models of generic placode induction and of combinatorial placode specification are presented...
  61. Jang C, Chao J, Jones N, Yao L, Bessarab D, Kuo Y, et al. Two Pax genes, eye gone and eyeless, act cooperatively in promoting Drosophila eye development. Development. 2003;130:2939-51 pubmed
    ..Our results also show that eyg has two major functions: to promote cell proliferation in the eye disc and to promote eye development through suppression of wg transcription...
  62. McCabe K, Manzo A, Gammill L, Bronner Fraser M. Discovery of genes implicated in placode formation. Dev Biol. 2004;274:462-77 pubmed
    ..Importantly, the results uncover previously unknown commonalities in genes expressed by multiple placodes and shared properties between placodes and other migratory cells, like neural crest cells...
  63. Blentic A, Gale E, Maden M. Retinoic acid signalling centres in the avian embryo identified by sites of expression of synthesising and catabolising enzymes. Dev Dyn. 2003;227:114-27 pubmed
    ..This strategy provides a basis for understanding the phenotypes of retinoic acid teratology and retinoic acid-deficiency syndromes...
  64. Morris A, Drawbridge J, Steinberg M. Axolotl pronephric duct migration requires an epidermally derived, laminin 1-containing extracellular matrix and the integrin receptor alpha6beta1. Development. 2003;130:5601-8 pubmed
  65. Manley N, Selleri L, Brendolan A, Gordon J, Cleary M. Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs. Dev Biol. 2004;276:301-12 pubmed
    ..However, some aspects of the Pbx1 mutant phenotype included specific defects that were less severe than those found in known Hox mutant mice, suggesting that some functions of Hox proteins in this region are Pbx1-independent...
  66. Herranz H, Morata G, Milan M. calderón encodes an organic cation transporter of the major facilitator superfamily required for cell growth and proliferation of Drosophila tissues. Development. 2006;133:2617-25 pubmed
    ..Our results indicate that growth of imaginal cells may be modulated by two distinct, but coordinated, nutrient-sensing mechanisms: one cell-autonomous and the other humoral...
  67. Kojima T, Tsuji T, Saigo K. A concerted action of a paired-type homeobox gene, aristaless, and a homolog of Hox11/tlx homeobox gene, clawless, is essential for the distal tip development of the Drosophila leg. Dev Biol. 2005;279:434-45 pubmed
    ..Bar attenuates aristaless and clawless expression through Lim1 repression. Aristaless and Clawless proteins form a complex capable of binding to specific DNA targets, which cannot be well recognized solely by Aristaless or Clawless...
  68. Yao S, Lum L, Beachy P. The ihog cell-surface proteins bind Hedgehog and mediate pathway activation. Cell. 2006;125:343-57 pubmed
  69. Orlandi F, Rossi C, Orlandi E, Jakil M, Hallahan T, Macri V, et al. First-trimester screening for trisomy-21 using a simplified method to assess the presence or absence of the fetal nasal bone. Am J Obstet Gynecol. 2005;192:1107-11 pubmed
  70. Tran U, Pickney L, Ozpolat B, Wessely O. Xenopus Bicaudal-C is required for the differentiation of the amphibian pronephros. Dev Biol. 2007;307:152-64 pubmed
    ..This pathway is required for terminal differentiation of the late distal tubule of the Xenopus pronephros and regulates renal epithelial cell differentiation, which--when disrupted--results in PKD...
  71. Holzschuh J, Wada N, Wada C, Schaffer A, Javidan Y, Tallafuss A, et al. Requirements for endoderm and BMP signaling in sensory neurogenesis in zebrafish. Development. 2005;132:3731-42 pubmed
    ..Our results show that the endoderm regulates the differentiation of cranial sensory ganglia, which coordinates the cranial nerves with the segments that they innervate...
  72. Tamura Y, Shimano H, Kuroiwa T, Miki Y. Trigeminal neuralgia associated with a primitive trigeminal artery variant: case report. Neurosurgery. 2003;52:1217-9; discussion 1219-20 pubmed
    ..We report a case of trigeminal neuralgia associated with this PTA variant, and we discuss the characteristics of this vessel...
  73. Drummond I. Kidney development and disease in the zebrafish. J Am Soc Nephrol. 2005;16:299-304 pubmed
    ..This short review outlines recent progress in applying the zebrafish pronephros to issues of human health and development...
  74. Das S, Chattopadhyay R, Ghosh S, Goswami S, Chakravarty B, Chaudhury K. Reactive oxygen species level in follicular fluid--embryo quality marker in IVF?. Hum Reprod. 2006;21:2403-7 pubmed
    ..The objectives of this study were to examine reactive oxygen species (ROS) levels in follicular fluid of women undergoing IVF and to relate these levels to embryo formation and quality...
  75. Matsuda M, Keino H. Possible roles of beta-catenin in evagination of the optic primordium in rat embryos. Dev Growth Differ. 2001;43:391-400 pubmed
    ..These results suggest that beta-catenin regulates cell proliferation, breakdown of BM and changes in cell shape in the evaginating optic primordium to cause optic vesicle formation...
  76. Rosin D, Schejter E, Volk T, Shilo B. Apical accumulation of the Drosophila PDGF/VEGF receptor ligands provides a mechanism for triggering localized actin polymerization. Development. 2004;131:1939-48 pubmed
    ..Together, these results suggest that polarized PVR activation is necessary for the proper organization of the wing disc epithelium, by regulating the apical assembly of the actin cytoskeleton...
  77. Shinmen A, Honda A, Ohkawa M, Hirose M, Ogonuki N, Yuzuriha M, et al. Efficient production of intersubspecific hybrid mice and embryonic stem cells by intracytoplasmic sperm injection. Mol Reprod Dev. 2007;74:1081-8 pubmed
    ..Thus, ICSI using cryopreserved spermatozoa allows the efficient and immediate production of a number of F1 hybrid mice and ES cell lines, which can be used for polymorphic analysis of mouse genetics...
  78. Li W, Johnson S, Shelley W, Ferkowicz M, Morrison P, Li Y, et al. Primary endothelial cells isolated from the yolk sac and para-aortic splanchnopleura support the expansion of adult marrow stem cells in vitro. Blood. 2003;102:4345-53 pubmed
    ..These data suggest that 9.5-dpc yolk sac- and P-Sp-derived primary Tie2-GFP+Flk-1+CD41- endothelial cells possess the capacity to expand adult bone marrow hematopoietic progenitor cell and HSC repopulating ability ex vivo...
  79. McKinnell I, Makarenkova H, de Curtis I, Turmaine M, Patel K. EphA4, RhoB and the molecular development of feather buds are maintained by the integrity of the actin cytoskeleton. Dev Biol. 2004;270:94-105 pubmed
    ..We propose that this molecular maintenance mechanism between EphA4-RhoB and the actin cytoskeleton converges or coordinates with other morphogenic signalling systems to control feather bud development...
  80. Batut J, Vandel L, Leclerc C, Daguzan C, Moreau M, Neant I. The Ca2+-induced methyltransferase xPRMT1b controls neural fate in amphibian embryo. Proc Natl Acad Sci U S A. 2005;102:15128-33 pubmed
    ..The results presented provide insights by which a Ca2+ increase induces neural fate...
  81. Watanabe K, Nakamura M, Okano H, Toyama Y. Establishment of three-dimensional culture of neural stem/progenitor cells in collagen Type-1 Gel. Restor Neurol Neurosci. 2007;25:109-17 pubmed
    ..We, then, evaluated the ability of NSPCs to differentiate under the optimal condition...
  82. Miyazaki K, Tomii R, Kurome M, Ueda H, Hirakawa K, Ueno S, et al. Evaluation of the quality of porcine somatic cell nuclear transfer embryo by gene transcription profiles. J Reprod Dev. 2005;51:123-31 pubmed
    ..Our study suggests that expression profiles of FGFr72IIIb, IL6ralpha, and Xist can be used as markers for the diagnosis of the developmental potency of porcine nuclear transfer embryos...
  83. Svarcova O, Laurincik J, Avery B, Mlyncek M, Niemann H, Maddox Hyttel P. Nucleolar development and allocation of key nucleolar proteins require de novo transcription in bovine embryos. Mol Reprod Dev. 2007;74:1428-35 pubmed
    ..However, localization of these two proteins to the nucleolar compartments was negatively affected by the alpha-amanitin treatment. Consequently, functional nucleoli were not established...
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