ergotism

Summary

Alias: st anthonys fire, ergot poisoning, saint anthonys fire
Summary: Poisoning caused by ingesting ergotized grain or by the misdirected or excessive use of ergot as a medicine.

Webpages

  1. molecular expressions microscopy primer: specialized microscopy techniques - phase contrast photomicrography gallery - ergot (claviceps purpurea
    micro.magnet.fsu.edu/primer/techniques/phasegallery/ergotpha ...
  2. alkaloids
    www.people.vcu.edu/~asneden/alkaloids.htm
  3. lameness in cattle
    minds.wisconsin.edu/bitstream/1793/8351/1/AgNIC.xml
  4. lsd
    www.chm.bris.ac.uk/motm/lsd/lsd1_text.htm
  5. lsd
    www.ch.ic.ac.uk/rzepa/mim/drugs/html/lsd_text.htm
  6. ergotamine
    www.umm.edu/altmed/drugs/ergotamine-049100.htm
  7. molecular expressions microscopy primer: specialized microscopy techniques - phase contrast photomicrography gallery - ergot (claviceps purpurea
    microscopy.fsu.edu/primer/techniques/phasegallery/ergotphase ...
  8. texas toxic plants
    texnat.tamu.edu/cmplants/toxic/plants/dallisgrass.html
  9. what do i do if mycotoxins are present
    beef.osu.edu/library/mycotoxins.html
  10. ipm : reports on plant diseases : peach leaf curl and plum pockets ergot of cereals and grasses
    www.ipm.uiuc.edu/diseases/series100/rpd107/index.html

Publications

  1. Presumptive gangrenous ergotism in free-living moose and a roe deer
    Kjell Handeland
    Department of Animal Health, Section of Wildlife Diseases, National Veterinary Institute, PO Box 8156 Dep, NO 0033 Oslo, Norway
    J Wildl Dis 41:636-42
  2. Evidence that enforced sunlight exposure can cause hyperthermia in cattle ingesting low levels of ergot of rye (Claviceps purpurea), when air temperature and humidity conditions are only moderate
    C A Bourke
    NSW Agriculture, Orange Agricultural Institute, Forest Road, Orange, New South Wales 2800
    Aust Vet J 81:553-8
  3. Thermoregulatory response of dairy cows fed ergotized barley during summer heat stress
    Hosam J Al Tamimi
    Department of Animal Production, College of Agriculture, Mutah University, P O Box 7, Karak 61710, Jordan
    J Vet Diagn Invest 15:355-60
  4. Feeding sorghum ergot (Claviceps africana) to sows before farrowing inhibits milk production
    J S Kopinski
    Department of Primary Industries and Fisheries, Moorooka, QLD, Australia
    Aust Vet J 85:169-76
  5. Hyperthermic syndrome in dairy cattle associated with consumption of ergots of Claviceps purpurea in southern Brazil
    Marcia R S Ilha
    Department of Preventive Veterinary Medicine, State University of Londrina, 86051 990 Londrina, PR, Brazil
    Vet Hum Toxicol 45:140-5
  6. Ergotism unresponsive to multiple therapeutic modalities, including sodium nitroprusside, resulting in limb loss
    Khrongwong Musikatavorn
    Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Clin Toxicol (Phila) 46:157-8
  7. Painful ANA-positive scleroderma-like disease with acral ulcerations: a case of chronic gangrenous ergotism
    Uwe Wollina
    Department of Dermatology and Allergology, Academic Teaching Hosputal of the Technical University of Dresden, Dresden, Germany
    Int J Low Extrem Wounds 6:148-52
  8. [The shadow sides of the bio-boom. Where do fungi overall leave their poison behind]
    Adela Kraus-Zatecky
    MMW Fortschr Med 146:12
  9. Gangrenous ergotism in cattle grazing fescue (Festuca elatior L.) in South Africa
    C J Botha
    Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    J S Afr Vet Assoc 75:45-8
  10. Convulsive ergotism: epidemics of the serotonin syndrome?
    Mervyn J Eadie
    Department of Medicine, University of Queensland, and the Royal Brisbane Hospital, Brisbane, Australia
    Lancet Neurol 2:429-34

Scientific Experts

  • Uwe Wollina
  • Andrea Sinz
  • Khrongwong Musikatavorn
  • Donata Favretto
  • C Pajot
  • L A Ruano-Calderón
  • J S Kopinski
  • John C Morgan
  • F Stammler
  • Kjell Handeland
  • Alec Aeby
  • Caroline M de Costa
  • Mervyn J Eadie
  • J A Parish
  • C J Botha
  • Tim J Evans
  • Giovanni Brancaccio
  • Mary K Matossian
  • Afshin M Molkara
  • Hutan Ashrafian
  • Aly M Ezz El Arab
  • Iram Naz
  • Stacey A Bangh
  • K Honein
  • Steve Ainsworth
  • Adela Kraus-Zatecky
  • M Sallansonnet Froment
  • Stanley H Schuman
  • Zachary K Baldwin
  • C A Bourke
  • Marcia R S Ilha
  • Hosam J Al Tamimi
  • Werner Dettelbacher
  • Katharina Arnheim
  • M Faure
  • Marc A Tribble
  • M V Copetti
  • Eman M Hegazy
  • J David Killeen
  • Ahmed M Abou Zamzam
  • Ahmed M Abou-Zamzam
  • Jacobus De Varagine
  • Aly M Ezz El-Arab
  • Ziad Sophie
  • Christian Bianchi
  • Azzat B Abd El-Khalek
  • Shenouda M Girgis
  • Azzat B Abd El Khalek
  • Theodore H Teruya
  • J Boujaoude
  • M Chemaly
  • C Yaghi
  • Kirk A Hughes
  • Steven M Kovarik
  • R Sayegh
  • David J Roberts
  • R Karam
  • A Blohorn Sense
  • B Mihout
  • Y Onnient
  • E Guegan Massardier
  • A Blohorn-Sense
  • M Sallansonnet-Froment
  • A Triquenot-Bagan
  • G Godeneche
  • E Guegan-Massardier
  • R B Lipton
  • A Triquenot Bagan
  • Darryl Chatman
  • Hosam J Al-Tamimi
  • Chris C Ceraldi
  • George E Rottinghaus
  • Mathias Gothard
  • Jim Spain
  • Thomas L Carson
  • Donald E Spiers
  • Peggy A Eichen
  • Alexandre P Loretti
  • Claudio S L Barros
  • S H Alves
  • L A Bergermaier
  • A T Leal
  • L Ferreiro
  • Robin Amirkhan
  • A A P Boeck
  • James W Smith
  • Clark R Gregg
  • A B M Leal
  • J M Santurio
  • I Lubeck
  • David M Margolis
  • R B Silva

Detail Information

Webpages18

  1. molecular expressions microscopy primer: specialized microscopy techniques - phase contrast photomicrography gallery - ergot (claviceps purpurea
    micro.magnet.fsu.edu/primer/techniques/phasegallery/ergotpha ...
  2. alkaloids
    www.people.vcu.edu/~asneden/alkaloids.htm
  3. lameness in cattle
    minds.wisconsin.edu/bitstream/1793/8351/1/AgNIC.xml
  4. lsd
    www.chm.bris.ac.uk/motm/lsd/lsd1_text.htm
  5. lsd
    www.ch.ic.ac.uk/rzepa/mim/drugs/html/lsd_text.htm
  6. ergotamine
    www.umm.edu/altmed/drugs/ergotamine-049100.htm
  7. molecular expressions microscopy primer: specialized microscopy techniques - phase contrast photomicrography gallery - ergot (claviceps purpurea
    microscopy.fsu.edu/primer/techniques/phasegallery/ergotphase ...
  8. texas toxic plants
    texnat.tamu.edu/cmplants/toxic/plants/dallisgrass.html
  9. what do i do if mycotoxins are present
    beef.osu.edu/library/mycotoxins.html
  10. ipm : reports on plant diseases : peach leaf curl and plum pockets ergot of cereals and grasses
    www.ipm.uiuc.edu/diseases/series100/rpd107/index.html
  11. world food habits bibliography
    lilt.ilstu.edu/rtdirks/DISEASE.html
  12. claviceps purpurea, cause of ergotism-- likely contributor to the salem witch trials, tom volk's fungus of the month for october1999
    botit.botany.wisc.edu/toms_fungi/oct99.html
  13. ergonovine
    www.umm.edu/altmed/drugs/ergonovine-048800.htm
  14. alkaloids
    webspace.ship.edu/calove/ALKALOIDS.htm
  15. roget's thesaurus -- section v. results of reasoning
    www.dcc.fc.up.pt/~mig/dic/htmlmroget/mroget_74.html#e503
  16. ipm : reports on plant diseases : stem rust of small grains and grasses
    www.ipm.uiuc.edu/diseases/series100/rpd118/index.html
  17. ipm : reports on plant diseases : stem rust of small grains and grasses
    www.ipm.uiuc.edu/diseases/series100/rpd108/index.html

Publications42

  1. Presumptive gangrenous ergotism in free-living moose and a roe deer
    Kjell Handeland
    Department of Animal Health, Section of Wildlife Diseases, National Veterinary Institute, PO Box 8156 Dep, NO 0033 Oslo, Norway
    J Wildl Dis 41:636-42
    Presumptive gangrenous ergotism in 10 moose (Alces alces) and one roe deer (Capreolus capreolus) is reported. Three of the moose came from a municipality in southeastern Norway where the disease occurred as a cluster in 1996...
  2. Evidence that enforced sunlight exposure can cause hyperthermia in cattle ingesting low levels of ergot of rye (Claviceps purpurea), when air temperature and humidity conditions are only moderate
    C A Bourke
    NSW Agriculture, Orange Agricultural Institute, Forest Road, Orange, New South Wales 2800
    Aust Vet J 81:553-8
    ..A response to radiant heat is consistent with the known physiological effects of ingested ergot alkaloids, but a response to solar radiation is not...
  3. Thermoregulatory response of dairy cows fed ergotized barley during summer heat stress
    Hosam J Al Tamimi
    Department of Animal Production, College of Agriculture, Mutah University, P O Box 7, Karak 61710, Jordan
    J Vet Diagn Invest 15:355-60
    ..Therefore, the ergopeptine alkaloid dose used in this study represents a level for minimal induction of the ergot toxicity response...
  4. Feeding sorghum ergot (Claviceps africana) to sows before farrowing inhibits milk production
    J S Kopinski
    Department of Primary Industries and Fisheries, Moorooka, QLD, Australia
    Aust Vet J 85:169-76
    ..CONCLUSION: Sorghum ergot should not exceed 0.3% (1 mg alkaloid/kg) in diets of multiparous sows fed before farrowing, and should be limited to 0.1% for primiparous sows, or avoided completely...
  5. Hyperthermic syndrome in dairy cattle associated with consumption of ergots of Claviceps purpurea in southern Brazil
    Marcia R S Ilha
    Department of Preventive Veterinary Medicine, State University of Londrina, 86051 990 Londrina, PR, Brazil
    Vet Hum Toxicol 45:140-5
    ..Diagnosis was based on epidemiology, clinical signs and pathology. The pathogenetic mechanisms involved in the occurrence of HS are briefly discussed...
  6. Ergotism unresponsive to multiple therapeutic modalities, including sodium nitroprusside, resulting in limb loss
    Khrongwong Musikatavorn
    Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Clin Toxicol (Phila) 46:157-8
    Unlike epidemics in past centuries, patients suffering from peripheral vascular ischemia related to ergotism now rarely lose a limb because of vasodilator therapies...
  7. Painful ANA-positive scleroderma-like disease with acral ulcerations: a case of chronic gangrenous ergotism
    Uwe Wollina
    Department of Dermatology and Allergology, Academic Teaching Hosputal of the Technical University of Dresden, Dresden, Germany
    Int J Low Extrem Wounds 6:148-52
    Chronic ergotism is a rare cause of limb ischemia...
  8. [The shadow sides of the bio-boom. Where do fungi overall leave their poison behind]
    Adela Kraus-Zatecky
    MMW Fortschr Med 146:12
  9. Gangrenous ergotism in cattle grazing fescue (Festuca elatior L.) in South Africa
    C J Botha
    Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa
    J S Afr Vet Assoc 75:45-8
    ..Ergovaline concentrations in basal leaf sheaths and grass stems collected during the outbreak ranged from 1720-8170 ppb on a dry-matter basis...
  10. Convulsive ergotism: epidemics of the serotonin syndrome?
    Mervyn J Eadie
    Department of Medicine, University of Queensland, and the Royal Brisbane Hospital, Brisbane, Australia
    Lancet Neurol 2:429-34
    Between 1085 and 1927, epidemics of "convulsive ergotism" were widespread east of the Rhine in Europe due to consumption of grain contaminated with ergot, which is produced by the fungus Claviceps purpurea...
  11. Agalactia in mares fed with grain contaminated with Claviceps purpurea
    M V Copetti
    Department of Preventive Veterinary Medicine, Universidade Federal de Santa Maria, RS, Brazil
    Mycopathologia 154:199-200
    ..Laboratory analysis of oat samples fed to the animals resulted in the identification of Claviceps purpurea sclerotia. The fungus was identified in 0.22% of the examined seeds...
  12. Endocrine alterations associated with ergopeptine alkaloid exposure during equine pregnancy
    Tim J Evans
    Veterinary Medical Diagnostic Laboratory, Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri at Columbia, Columbia, MO 65211, USA
    Vet Clin North Am Equine Pract 18:371-8, viii
    ..An understanding of the endocrine alterations associated with ergopeptine alkaloid exposure during pregnancy is necessary for the diagnosis of potential exposure to these compounds and for eective prophylaxis and therapy...
  13. [Digitalis -- poisoning, myopathy, ergotism.... When antibiotic and associated therapy become dangerous mixture]
    Katharina Arnheim
    MMW Fortschr Med 145:12-3
  14. Ergotism associated with HIV antiviral protease inhibitor therapy
    Zachary K Baldwin
    Department of Surgery, Kaiser Permanente Oakland, 280 W MacArthur Boulevard, Oakland, CA 94611, USA
    J Vasc Surg 37:676-8
    b>Ergotism is a rare condition of acute vasospasm found classically in young and middle-aged women taking ergot alkaloid agents to treat migraine headache...
  15. Highly specific quantification of ergotamine in urine, blood, and hair samples by liquid chromatography-tandem mass spectrometry
    Donata Favretto
    Forensic Toxicology and Antidoping, University Hospital of Padova, Padova, Italy
    Ther Drug Monit 29:325-32
    ..It is highly toxic and in large, repeated doses can produce all the symptoms of ergot poisoning. A selective and sensitive method, based on liquid chromatography-tandem mass spectrometry (LC-MS2), has been ..
  16. Use of nonergot alkaloid-producing endophytes for alleviating tall fescue toxicosis in sheep
    J A Parish
    Department of Animal and Dairy Science, The University of Georgia, Athens 30602 7385, USA
    J Anim Sci 81:1316-22
    ....
  17. Chronic ergot toxicity presenting with bilateral external iliac artery dissection and lower extremity rest pain
    Afshin M Molkara
    Division of Vascular Surgery, Department of Surgery, Loma Linda University Medical Center, Loma Linda, CA 92354, USA
    Ann Vasc Surg 20:803-8
    ..Endovascular or surgical interventions may be considered in patients with ergot toxicity for specific indications or those whose symptoms progress despite conservative management...
  18. [Critical ischaemia of the limbs and localized livedo in a case of ergotism]
    F Stammler
    Abteilung Innere Medizin des Sanakrankenhauses Wildbad, Germany
    Dtsch Med Wochenschr 127:144-8
    ..The history of drug intake and the characteristic sonographic findings indicated ergotism and an arteriography was deemed unnecessary...
  19. Fatal ergotism induced by an HIV protease inhibitor
    Marc A Tribble
    Headache 42:694-5
  20. How can a migraine cause faecal incontinence?
    K Honein
    Department of Gastroenterology, Hotel-Dieu de France Hospital, Saint-Joseph University, Beirut, Lebanon
    Gut 54:1817, 1824
  21. [The development of ergot alkaloids as drugs]
    Andrea Sinz
    Abteilung für Pharmazeutische Chemie and Bioanalytik, Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Wolfgang-Langenbeck-Strasse 4, D-06120 Halle, Saale, Germany
    Pharm Unserer Zeit 37:306-9
  22. Acute limb ischemia due to ergotism
    Iram Naz
    Department of Surgery, Section of Vascular Surgery, Aga Khan University, Karachi, Pakistan
    J Coll Physicians Surg Pak 16:553-5
    ..We are reporting two cases of extremity ischemia secondary to ergot poisoning. The first patient was a 60 years old woman, who presented with a 15 days history of ischemia of the left arm ..
  23. Methylergometrine poisoning in children: review of 34 cases
    Alec Aeby
    Neonatal Intensive Care Unit, Children University Hospital Reine Fabiola, Free University of Brussels U L B, Brussels, Belgium
    J Toxicol Clin Toxicol 41:249-53
    ..We describe the first case of oral methylergometrine poisoning requiring mechanical ventilation and alert physicians that oral exposure to methylergometrine may lead to severe complications...
  24. Neonatal ergot poisoning: a persistent iatrogenic illness
    Stacey A Bangh
    Hennepin Regional Poison Center, Hennepin County Medical Center, Minneapolis, Minnesota 55415, USA
    Am J Perinatol 22:239-43
    ..Rapid recognition of the therapeutic error, ventilatory support, and prompt administration of sodium nitroprusside should lead to a good outcome...
  25. Ergotamine tartrate and dihydroergotamine mesylate: safety profiles
    R B Lipton
    Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY 10467, USA
    Headache 37:S33-41
    ..chronic usage) include nausea, acroparesthesia, ischemia, habituation and overuse headache, and, rarely, overt ergotism. Reports of serious adverse effects following recommended doses of DHE are rare...
  26. Effect of dietary honey on intestinal microflora and toxicity of mycotoxins in mice
    Aly M Ezz El Arab
    Department of Food Science and Nutrition, National Research Center, 12644 Dokki, Giza, Egypt
    BMC Complement Altern Med 6:6
    ..CONCLUSION: Substituting sugars with honey in processed food can inhibit the harmful and genotoxic effects of mycotoxins, and improve the gut microflora...
  27. Three saints and critical limb ischemia
    Hutan Ashrafian
    Ann Vasc Surg 20:553-4
  28. Ergotism
    Giovanni Brancaccio
    Chirurgia Vascolare Ospedale S.Andrea, La Spezia, Italy
    J Vasc Surg 48:754
  29. St Anthony's fire and living ligatures: a short history of ergometrine
    Caroline De Costa
    Department of Obstetrics and Gynaecology, Cairns Base Hospital, PO Box 902, Cairns 4870, Queensland, Australia
    Lancet 359:1768-70
  30. Plant chemicals: poisons and cures
    Stanley H Schuman
    J Agromedicine 9:17-21
  31. Burn the witch
    Steve Ainsworth
    Pract Midwife 8:46
  32. [About the acting of the brotherhood of St. Anthony in Würzburg]
    Werner Dettelbacher
    Wurzbg Medizinhist Mitt 22:81-8
    ..In their infirmaries the monks took care of the persons attacked by ergot poisoning. If prayers and ointments were of no avail, in most cases the lower leg was amputated, so that the vital ..
  33. Why the Quakers quaked: the influence of climatic change on Quaker health, 1647-1659
    Mary K Matossian
    Quaker Hist 96:36-51
  34. [Ergotism, smallpox and halo-nevus at the onset of the sixteenth century]
    M Faure
    Service de Dermatologie, Pavillon R, Hôpital Edouard Herriot, 69437 Lyon 03
    Ann Dermatol Venereol 130:1182-6
  35. [Chronic ergotism: spinal lesion and neuropathy]
    M Sallansonnet Froment
    Département de Neurologie, Hôpital Charles Nicolle, Rouen
    Rev Neurol (Paris) 160:843-5
    INTRODUCTION: Neuropathologic manifestations due to chronic ergotism are rare...
  36. Pergolide-induced ergotism
    John C Morgan
    Movement Disorders Program, Department of Neurology, Medical College of Georgia, 1429 Harper Street, HF-1121, Augusta, GA 30912, USA
    Neurology 67:104
  37. [Atypical glossitis]
    C Pajot
    Service de Dermatologie, Centre Hospitalier du Mans, Le Mans
    Ann Dermatol Venereol 132:901-2