warts

Summary

Summary: Benign epidermal proliferations or tumors; some are viral in origin.

Top Publications

  1. ncbi Successful treatment of periungual warts using photodynamic therapy: a pilot study
    C A Schroeter
    Department of Lasertherapy, Medical Centre Maastricht, Maastricht, The Netherlands
    J Eur Acad Dermatol Venereol 21:1170-4. 2007
  2. ncbi Management of cutaneous warts: an evidence-based approach
    Giuseppe Micali
    Dermatology Clinic, University of Catania, Catania, Italy
    Am J Clin Dermatol 5:311-7. 2004
  3. ncbi Evidence-based review of management of nongenital cutaneous warts
    Tracy D Kuykendall-Ivy
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Cutis 71:213-22. 2003
  4. ncbi Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial
    F T Al-Gurairi
    Department of Dermatology and Venereology, Baghdad Teaching Hospital, Baghdad, Iraq
    Br J Dermatol 146:423-31. 2002
  5. ncbi Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts
    S M Johnson
    Department of Dermatology, University of Arkansas for Medical Sciences, 4301 W Markham, Slot 576, Child Study Center Room 124a, Little Rock, AR 72205, USA
    Arch Dermatol 137:451-5. 2001
  6. ncbi Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
    Paolo A Hernandez
    Department of Human Genetics, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, New York 10029, USA
    Nat Genet 34:70-4. 2003
  7. ncbi WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12
    Karl Balabanian
    Unite d Immunologie Virale, Institut Pasteur, 75724 Paris, France
    Blood 105:2449-57. 2005
  8. ncbi Detection of a novel bovine papillomavirus type 11 (BPV-11) using xipapillomavirus consensus polymerase chain reaction primers
    Shinichi Hatama
    Hokkaido Research Station, National Institute of Animal Health, 4 Hitsujigaoka, Toyohira, Sapporo, 062 0045, Japan
    Arch Virol 156:1281-5. 2011
  9. ncbi The use of diphenylcyclopropenone in the treatment of recalcitrant warts
    Jennifer A Upitis
    University of Alberta, Edmonton, Alberta, Canada
    J Cutan Med Surg 6:214-7. 2002
  10. pmc The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome
    David C Dale
    Department of Medicine, University of Washington, Seattle, WA, USA
    Blood 118:4963-6. 2011

Detail Information

Publications280 found, 100 shown here

  1. ncbi Successful treatment of periungual warts using photodynamic therapy: a pilot study
    C A Schroeter
    Department of Lasertherapy, Medical Centre Maastricht, Maastricht, The Netherlands
    J Eur Acad Dermatol Venereol 21:1170-4. 2007
    The aim of this pilot study was an investigation on photodynamic therapy (PDT) whether it is a good alternative for treating periungual and subungual warts of the hands.
  2. ncbi Management of cutaneous warts: an evidence-based approach
    Giuseppe Micali
    Dermatology Clinic, University of Catania, Catania, Italy
    Am J Clin Dermatol 5:311-7. 2004
    Cutaneous warts are benign epidermal proliferations caused by human papillomavirus infection...
  3. ncbi Evidence-based review of management of nongenital cutaneous warts
    Tracy D Kuykendall-Ivy
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock 72205, USA
    Cutis 71:213-22. 2003
    ..Human papillomavirus (HPV)-induced tumors of the skin are often varied in clinical presentation, ranging from benign warts to malignant neoplasms...
  4. ncbi Oral zinc sulphate in the treatment of recalcitrant viral warts: randomized placebo-controlled clinical trial
    F T Al-Gurairi
    Department of Dermatology and Venereology, Baghdad Teaching Hospital, Baghdad, Iraq
    Br J Dermatol 146:423-31. 2002
    Viral warts are common dermatological diseases; although the rate of spontaneous recovery is high, it usually takes a long time, and some patients might not show this spontaneous healing...
  5. ncbi Intralesional injection of mumps or Candida skin test antigens: a novel immunotherapy for warts
    S M Johnson
    Department of Dermatology, University of Arkansas for Medical Sciences, 4301 W Markham, Slot 576, Child Study Center Room 124a, Little Rock, AR 72205, USA
    Arch Dermatol 137:451-5. 2001
    b>Warts are common and induce physical and emotional discomfort. Numerous therapies exist, yet none is optimal. Despite theoretical advantages, immunotherapeutic modalities are often neglected as first-line wart therapies.
  6. ncbi Mutations in the chemokine receptor gene CXCR4 are associated with WHIM syndrome, a combined immunodeficiency disease
    Paolo A Hernandez
    Department of Human Genetics, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, New York 10029, USA
    Nat Genet 34:70-4. 2003
    ....
  7. ncbi WHIM syndromes with different genetic anomalies are accounted for by impaired CXCR4 desensitization to CXCL12
    Karl Balabanian
    Unite d Immunologie Virale, Institut Pasteur, 75724 Paris, France
    Blood 105:2449-57. 2005
    The WHIM syndrome is a rare immunodeficiency disorder characterized by warts, hypogammaglobulinemia, infections, and myelokathexis...
  8. ncbi Detection of a novel bovine papillomavirus type 11 (BPV-11) using xipapillomavirus consensus polymerase chain reaction primers
    Shinichi Hatama
    Hokkaido Research Station, National Institute of Animal Health, 4 Hitsujigaoka, Toyohira, Sapporo, 062 0045, Japan
    Arch Virol 156:1281-5. 2011
    ..These methods were used to detect the partial L1 nucleotide sequence of BPV types from 167 cutaneous warts in cattle. Three potentially new viruses were detected using subBup/subBdw primer sets...
  9. ncbi The use of diphenylcyclopropenone in the treatment of recalcitrant warts
    Jennifer A Upitis
    University of Alberta, Edmonton, Alberta, Canada
    J Cutan Med Surg 6:214-7. 2002
    The treatment of recalcitrant palmoplantar and periungual warts using topical immunotherapy with diphenylcyclopropenone (DPC) was reviewed retrospectively over a seven-year period.
  10. pmc The CXCR4 antagonist plerixafor is a potential therapy for myelokathexis, WHIM syndrome
    David C Dale
    Department of Medicine, University of Washington, Seattle, WA, USA
    Blood 118:4963-6. 2011
    ..08 mg/kg dose. None of the patients experienced any significant adverse effects. Plerixafor is a promising therapy for this condition...
  11. ncbi Enhanced function with decreased internalization of carboxy-terminus truncated CXCR4 responsible for WHIM syndrome
    Toshinao Kawai
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1456, USA
    Exp Hematol 33:460-8. 2005
    WHIM (warts, hypogammaglobulinemia, recurrent bacterial infection, myelokathexis) syndrome is an autosomal dominant immune deficiency with severe chronic neutropenia and marrow neutrophil apoptosis...
  12. ncbi Topical treatments for cutaneous warts
    Chun Shing Kwok
    Norwich Medical School, University of East Anglia, Norwich, UK
    Cochrane Database Syst Rev 9:CD001781. 2012
    Viral warts are a common skin condition, which can range in severity from a minor nuisance that resolve spontaneously to a troublesome, chronic condition. Many different topical treatments are available.
  13. pmc Warts and all: human papillomavirus in primary immunodeficiencies
    Jennifer W Leiding
    Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892 1684, USA
    J Allergy Clin Immunol 130:1030-48. 2012
    ..We review immunodeficiencies with severe HPV infections and the mechanisms underlying them...
  14. ncbi Intravenous cidofovir treatment for recalcitrant warts in the setting of a patient with myelodysplastic syndrome
    D Grone
    Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Eur Acad Dermatol Venereol 20:202-5. 2006
    ..We report for the first time on the promotion of the healing of recalcitrant warts in a patient with myelodysplastic syndrome with intravenous cidofovir treatment.
  15. pmc WHIM syndrome caused by a single amino acid substitution in the carboxy-tail of chemokine receptor CXCR4
    Qian Liu
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA
    Blood 120:181-9. 2012
    WHIM syndrome is a rare, autosomal dominant, immunodeficiency disorder so-named because it is characterized by warts, hypogammaglobulinemia, infections, and myelokathexis (defective neutrophil egress from the BM)...
  16. ncbi Polyphenon E: a new treatment for external anogenital warts
    S Tatti
    The Hospital Clinicas, Universidad de Buenos Aires, Av Cordoba 2351, Buenos Aires 1120, Argentina
    Br J Dermatol 162:176-84. 2010
    Background External genital warts (EGWs, condylomata acuminata) are a common, highly contagious disease caused by human papillomavirus (HPV), predominantly HPV 6 and HPV 11...
  17. ncbi Prevalence of childhood acne, ephelides, warts, atopic dermatitis, psoriasis, alopecia areata and keloid in Kaohsiung County, Taiwan: a community-based clinical survey
    Y C Yang
    Department of Dermatology, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Taiwan
    J Eur Acad Dermatol Venereol 21:643-9. 2007
    ..Epidemiological study on childhood dermatoses performed by direct inspection of dermatologists is limited...
  18. ncbi A pivotal role for CXCL12 signaling in HPV-mediated transformation of keratinocytes: clues to understanding HPV-pathogenesis in WHIM syndrome
    Ken Y C Chow
    INSERM U819, Unité Pathogénie Virale, Institut Pasteur, 75724 Paris Cedex 15, France
    Cell Host Microbe 8:523-33. 2010
    ..These results establish a pivotal role for CXCL12 signaling in HPV-mediated transformation and provide a mechanistic basis for understanding HPV pathogenesis in WHIM syndrome...
  19. pmc CD4+ cell count and HIV load as predictors of size of anal warts over time in HIV-infected women
    Hung N Luu
    Dan L Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA
    J Infect Dis 205:578-85. 2012
    ..This study examined whether CD4(+) count and HIV load predict the size of the largest anal warts in 976 HIV-infected women in an ongoing cohort.
  20. ncbi Proliferation and invasion factors in HIV-associated dysplastic and nondysplastic oral warts and in oral squamous cell carcinoma: an immunohistochemical and RT-PCR evaluation
    Joseph A Regezi
    Division of Oral Medicine, Pathology and Radiology, School of Dentistry, University of California San Francisco, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:724-31. 2002
    Oral warts arising in human immunodeficiency virus (HIV) infection occasionally show marked epithelial dysplasia. However, anecdotal evidence suggests that they do not progress to oral squamous cell carcinoma (SCC)...
  21. ncbi Bleomycin treatment of warts
    Martin S Horn
    Cutis 76:25; author reply 25-6. 2005
  22. ncbi Efficacy and tolerability of topical 1% cidofovir cream for the treatment of external anogenital warts in HIV-infected persons
    A Matteelli
    Clinic of Infectious and Tropical Diseases, University of Brescia, Italy
    Sex Transm Dis 28:343-6. 2001
    Treatment options for anogenital warts in patients with HIV-1 are unsatisfactory because they fail to eradicate latent human papillomavirus.
  23. pmc CXCL12/CXCR4-axis dysfunctions: Markers of the rare immunodeficiency disorder WHIM syndrome
    Françoise Bachelerie
    Pathogénie Virale, INSERM U819, Institut Pasteur, 25 28 Rue du Dr Roux, 75015 Paris, France
    Dis Markers 29:189-98. 2010
    The WHIM syndrome features susceptibility to human Papillomavirus infection-induced warts and carcinomas, hypogammaglobulinemia, recurrent bacterial infections, B and T-cell lymphopenia, and neutropenia associated with retention of ..
  24. ncbi Warts in primary schoolchildren: prevalence and relation with environmental factors
    F M van Haalen
    Department of Public Health and Primary Care, Leiden University Medical Centre, PO Box 9600, Leiden 2300 RC, The Netherlands
    Br J Dermatol 161:148-52. 2009
    b>Warts are very common in primary schoolchildren. However, knowledge on wart epidemiology and causes of wart transmission is scarce.
  25. ncbi WHIM syndrome and oral squamous cell carcinoma
    Nicole A Cipriani
    Department of Pathology, University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:105-8. 2010
    WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome is an autosomal dominant disease related to a mutation in the chemokine receptor CXCR4 resulting in altered immune function...
  26. ncbi WHIM syndrome
    John B Hagan
    Division of Allergic Diseases and Division of Hematopathology, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 82:1031. 2007
  27. ncbi [The Whim syndrome: a rare cause of diffuse bronchiectasis. Immune defect of CXCR4 and chronic bronchial suppuration]
    H Vinurel
    Service de Pneumologie, Centre Hospitalier Lyon Sud, HCL, Lyon, France
    Rev Mal Respir 25:614-8. 2008
    Whim syndrome, an association of warts, hypogammaglobulinemia, recurrent bacterial infections and the retention of mature polymorphonuclear cells within the bone marrow is an orphan disease...
  28. ncbi Comparing therapy costs for physician treatment of warts
    Robert J Clemons
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    J Drugs Dermatol 2:649-54. 2003
    To compare the cost of several common modalities used to treat non-genital warts in immunocompetent patients, we identified studies published in English using standard search strategies and evaluated the literature for the following ..
  29. ncbi HPV-associated oral warts
    L Feller
    Department of Periodontology and Oral Medicine, School of Oral Health Sciences, Faculty of Health Sciences, University of Limpopo, Medunsa Campus, South Africa
    SADJ 66:82-5. 2011
    ..papilloma, oral verruca vulgaris (common wart) and oral condyloma acuminatum, are collectively referred to as oral warts. Oral warts are usually asymptomatic, may be persistent or uncommonly, may regress spontaneously...
  30. ncbi Pulsed dye laser treatment for viral warts: a study of 120 patients
    Hyun Su Park
    Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, South Korea
    J Dermatol 35:491-8. 2008
    ..with pulsed dye laser was performed to evaluate the efficacy and safety of pulsed dye laser treatment for viral warts and to demonstrate the proper application and effective technique of this method...
  31. ncbi Stromal-derived factor-1 abolishes constitutive apoptosis of WHIM syndrome neutrophils harbouring a truncating CXCR4 mutation
    Duangmanee Sanmun
    Division of Biochemical Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Br J Haematol 134:640-4. 2006
    b>Warts, hypogammaglobulinaemia, infections, myelokathexis (WHIM) syndrome is an inherited immune disorder associated with CXCR4 gene mutations...
  32. pmc Familial occurrence of warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome
    Maciej Siedlar
    Department of Clinical Immunology, Polish American Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265, 30 663 Cracow, Poland
    Arch Immunol Ther Exp (Warsz) 56:419-25. 2008
    b>Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare immunodeficiency disorder with an autosomal-dominant pattern of inheritance and low fatality rate but significant lifelong morbidity.
  33. ncbi Nonsexual transmission of anogenital warts in children: a retrospective analysis
    Valerie Jones
    Division of Adolescent Medicine, Department of Pediatrics, University of Kentucky, Lexington, KY40536, USA
    ScientificWorldJournal 7:1896-9. 2007
    ..patients who were referred to a pediatric gynecologist for evaluation based on the clinical findings of anogenital warts. A retrospective analysis was performed on 131 patients between the ages 6 month and 9 years referred to a ..
  34. ncbi The WHIM syndrome shows a peculiar dysgranulopoiesis: myelokathexis
    Veronique Latger-Cannard
    Department of Biological Haematology, CHU Nancy, Vandoeuvre les Nancy, France
    Br J Haematol 132:669. 2006
  35. ncbi Zinc deficiency in patients with persistent viral warts
    Naeem Raza
    Department of Dermatology, PAF Hospital Faisal, Shahrah e Faisal, Karachi
    J Coll Physicians Surg Pak 20:83-6. 2010
    To determine the association of low serum zinc levels with persistent, progressive or recurrent viral warts.
  36. ncbi Detection and identification of human papillomavirus types isolated from Korean patients with flat warts
    Hoon Yoo
    Department of Pharmacology and Dental Therapeutics, College of Dentistry, Chosun University, Korea
    Microbiol Immunol 49:633-8. 2005
    Flat warts, also called verruca planna (VP) or juvenile warts, are benign epithelial proliferations of the skin caused by infection with human papillomaviruses (HPV)...
  37. ncbi Retinoids strongly and selectively correlate with keratin 13 and not keratin 19 expression in cutaneous warts of renal transplant recipients
    Willeke A M Blokx
    Department of Pathology, University Medical Center St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Arch Dermatol 138:61-5. 2002
    To compare the expression of keratin (K) 13 and K19 in cutaneous warts of renal transplant recipients (RTRs) and immunocompetent individuals (ICIs).
  38. ncbi Intralesional bleomycin for warts: a review
    Thomas G Lewis
    Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Drugs Dermatol 5:499-504. 2006
    Intralesional bleomycin has been used for the treatment of warts since the 1970s...
  39. ncbi Current choices in the treatment of cutaneous warts: a survey among Dutch GP
    Sjoerd C Bruggink
    Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
    Fam Pract 27:549-53. 2010
    GPs apply several treatments for patients with cutaneous warts. Available evidence recommends salicylic acid application.
  40. ncbi Human leukocyte antigen class II alleles and natural history of HPV 2/27/57-induced common warts
    Bettina Spelten
    Department of Dermatology, University Hospital of the RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    Arch Dermatol Res 296:105-11. 2004
    ..cervical cancer, we wanted to elucidate the role of HLA-class II allele polymorphisms in the persistence of common warts induced by HPV 2, HPV 27 or HPV 57...
  41. pmc Warts, cancer and ubiquitylation: lessons from the papillomaviruses
    Peter M Howley
    Department of Pathology, Harvard Medical School, 77 Avenue Louis Pateur, Boston, Massachusetts 02115, USA
    Trans Am Clin Climatol Assoc 117:113-26; discussion 126-7. 2006
    ..E6AP is an E3 ubiquitin protein ligase and is not normally involved in the regulation of p53 stability in the absence of E6. E6AP is the prototype for the HECT domain family of E3 ubiquitin protein ligases...
  42. ncbi Treatment of warts
    Courtney E Garry
    N Engl J Med 351:1692-3; author reply 1692-3. 2004
  43. ncbi Bacille Calmette-Guerin immunotherapy of viral warts
    Khalifa E Sharquie
    Scientific Council of Dermatology and Venereology, Iraqi Board for Medical Specializations, Medical Collection Office, Baghdad, Iraq
    Saudi Med J 29:589-93. 2008
    To assess the effectiveness of the Bacille Calmette-Guerin BCG vaccine in the treatment of viral warts.
  44. ncbi CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome
    Bernard Lagane
    Unité de Pathogénie Virale Moléculaire, Institut Pasteur, Paris, France
    Blood 112:34-44. 2008
    WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome is an immune deficiency linked in many cases to heterozygous mutations causing truncations in the cytoplasmic tail of CXC chemokine receptor 4 (CXCR4)...
  45. pmc The CXCR4 antagonist plerixafor corrects panleukopenia in patients with WHIM syndrome
    David H McDermott
    Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Blood 118:4957-62. 2011
    WHIM syndrome is a rare congenital immunodeficiency disorder characterized by warts, hypogammaglobulinemia, infections, and myelokathexis (neutropenia because of impaired egress from the BM); most patients also have severe panleukopenia...
  46. ncbi CO2 laser treatment of warts in immunosuppressed patients
    Severin Lauchli
    Department of Dermatology, University Hospital, Zurich, Switzerland
    Dermatology 206:148-52. 2003
    A large proportion of chronically immunosuppressed patients suffer from recalcitrant viral warts. Furthermore, the incidence of nonmelanoma skin cancer is clearly elevated in this patient group and human papillomavirus is most likely to ..
  47. ncbi The influence of painful sunburns and lifetime sun exposure on the risk of actinic keratoses, seborrheic warts, melanocytic nevi, atypical nevi, and skin cancer
    Cornelis Kennedy
    Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands
    J Invest Dermatol 120:1087-93. 2003
    ..the effect of painful sunburns and lifetime sun exposure on the development of actinic keratoses and seborrheic warts in relation to the development of squamous cell carcinoma and basal cell carcinoma, and on the development of ..
  48. pmc WHIM syndrome: congenital immune deficiency disease
    Toshinao Kawai
    Department of Pediatrics, Jikei University School of Medicine, Tokyo, Japan
    Curr Opin Hematol 16:20-6. 2009
    b>Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is characterized by susceptibility to human papilloma virus infection-induced warts and carcinomas; neutropenia, B-cell lymphopenia and hypogammaglobulinema-..
  49. pmc Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling
    Karl Balabanian
    INSERM U819, Paris, France
    J Clin Invest 118:1074-84. 2008
    Leukocytes from individuals with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome, a rare immunodeficiency, and bearing a wild-type CXCR4 ORF (WHIM(WT)) display impaired CXCR4 internalization and ..
  50. pmc WHIM syndrome myelokathexis reproduced in the NOD/SCID mouse xenotransplant model engrafted with healthy human stem cells transduced with C-terminus-truncated CXCR4
    Toshinao Kawai
    Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases NIAID, National Institutes of Health NIH, Bldg 10 CRC 5 West Labs, Rm 5 3750, 10 Center Dr MSC 1456, Bethesda, MD 20892 1456, USA
    Blood 109:78-84. 2007
    WHIM(warts, hypogammaglobulinemia, recurrent bacterial infection, and myelokathexis) syndrome is a rare immunodeficiency caused in many cases by autosomal dominant C-terminal truncation mutations in the chemokine receptor CXCR4...
  51. ncbi Clinical and genetic features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) syndrome
    L Dotta
    Department of Pediatrics, Institute of Molecular Medicine Angelo Nocivelli, University of Brescia, Italy
    Curr Mol Med 11:317-25. 2011
    ..The acronym WHIM resumes the main features of the syndrome: Warts, Hypogammaglobulinemia, Infections and Myelokathexis, which is abnormal retention of mature neutrophils in the ..
  52. ncbi Topical zinc sulphate solution for treatment of viral warts
    Khalifa E Sharquie
    Scientific Council of Dermatology and Venereolgy, Iraqi Board for Medical Specializations, PO Box 61080, Postal Code 12114, Medical Collection Office, Baghdad, Iraq
    Saudi Med J 28:1418-21. 2007
    To assess the efficacy and safety of topical zinc sulphate solution in the treatment of plane and common warts.
  53. ncbi Topical 5-fluorouracil has no additional benefit in treating common warts with cryotherapy: a single-centre, double-blind, randomized, placebo-controlled trial
    N M Luk
    Department of Research Centre, The Chinese University of Hong Kong, Hong Kong, China
    Clin Exp Dermatol 31:394-7. 2006
    The role of topical 5-fluorouracil (5-FU) in treating common warts is not well defined. We tried to evaluate the efficacy and adverse effects of combination cryotherapy and topical 5% 5-FU ointment in the treatment of common warts...
  54. ncbi Treatment of extensive and recalcitrant viral warts with acitretin
    Yun Lim Choi
    Int J Dermatol 45:480-2. 2006
  55. pmc Cryotherapy versus salicylic acid for the treatment of plantar warts (verrucae): a randomised controlled trial
    Sarah Cockayne
    Department of Health Sciences, York Trials Unit, University of York, UK
    BMJ 342:d3271. 2011
    To compare the clinical effectiveness of cryotherapy versus salicylic acid for the treatment of plantar warts.
  56. ncbi WHIM syndrome: a defect in CXCR4 signaling
    George A Diaz
    Department of Human Genetics, Mount Sinai School of Medicine, One Gustave L Levy Place, Box 1498, New York, NY 10029, USA
    Curr Allergy Asthma Rep 5:350-5. 2005
    ..The first example of a human immunologic disease caused by mutation of a chemokine receptor was provided by WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome, a rare, combined immunodeficiency featuring an ..
  57. ncbi Treatment of extensive warts with etretinate: a clinical trial in 20 children
    C Gelmetti
    Dermatologic Department, University of Milan, Italy
    Pediatr Dermatol 4:254-8. 1987
    ..clinical-effectiveness of etretinate in the treatment of papilloma virus infections, 20 children with extensive warts were given this oral retinoid for a period not exceeding three months at a dosage of 1 mg per kg per day...
  58. pmc Cryotherapy with liquid nitrogen versus topical salicylic acid application for cutaneous warts in primary care: randomized controlled trial
    Sjoerd C Bruggink
    Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands
    CMAJ 182:1624-30. 2010
    Cryotherapy is widely used for the treatment of cutaneous warts in primary care. However, evidence favours salicylic acid application. We compared the effectiveness of these treatments as well as a wait-and-see approach.
  59. ncbi Distribution of human papillomavirus genotypes in plucked eyebrow hairs from Slovenian males with genital warts
    Bostjan J Kocjan
    Institute of Microbiology and Immunology, Medical Faculty, Zaloska 4, 1105 Ljubljana, Slovenia
    Infect Genet Evol 5:255-9. 2005
    ..human papillomaviruses (HPVs) in the plucked eyebrow hairs obtained from 49 Slovenian male patients with genital warts were investigated...
  60. ncbi Lymphangiectases are common underlying warts and in normal peritumoral skin: histologic evidence of decreased immune surveillance
    Joan Paul
    Divisions of Dermatopathology and Dermatology, Department of Pathology, Albany Medical Center, Albany, NY 12208, USA
    Am J Dermatopathol 33:152-60. 2011
    ..Lymphangiectases are a histologic sign of lymphostasis, which is associated with decreased immune cell trafficking and cell-mediated immunity...
  61. ncbi Threading warts: a beauty parlor dermatosis
    Rajesh Kumar
    Jagjivan Ram Hospital, Mumbai, India
    J Cosmet Dermatol 6:279-82. 2007
    ..Appearance of warts at the site of threading is an unusual phenomenon...
  62. ncbi New patient-applied therapy for anogenital warts is rated favourably by patients
    C O'Mahony
    Department of Genito Urinary Medicine, The Countess of Chester Hospital, Countess of Chester Health Park, Liverpool Road, Chester CH2 1UL, UK
    Int J STD AIDS 12:565-70. 2001
    Our objective was to determine patient attitudes to having genital warts, and their perceptions of their treatment with imiquimod and other therapies...
  63. ncbi Dermojet delivery of bleomycin for the treatment of recalcitrant plantar warts
    Elaine Agius
    Department of Dermatology, University College London Hospitals, London, UK
    J Dermatolog Treat 17:112-6. 2006
    Plantar warts may cause significant morbidity. Intralesional bleomycin is effective...
  64. ncbi Treatment of disseminated facial warts through contact immunotherapy with diphenylcyclopropenone (DPCP)
    Shahin Aghaei
    Department of Dermatology, Jahrom Medical School, Jahrom, Iran
    Dermatol Online J 12:10. 2006
    This paper highlights the effect of diphenylcyclopropenone (DPCP) sensitization on warts resistant to other treatments and is interesting in views of the fact that all the facial warts apparently responded...
  65. ncbi Human papillomavirus-associated oral warts among human immunodeficiency virus-seropositive patients in the era of highly active antiretroviral therapy: an emerging infection
    Mark D King
    Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, 30303, USA
    Clin Infect Dis 34:641-8. 2002
    Oral warts are a manifestation of human papillomavirus infection that have been noted infrequently in persons with human immunodeficiency virus (HIV)...
  66. ncbi Topical vitamin D3 derivatives for recalcitrant warts in three immunocompromised patients
    K Egawa
    Br J Dermatol 150:374-6. 2004
  67. ncbi Merkel cell polyomavirus is present in common warts and carcinoma in situ of the skin
    Kirsten D Mertz
    Kempf and Pfaltz Histological Diagnostics, Research Unit, Zurich, Switzerland
    Hum Pathol 41:1369-79. 2010
    ..anatomical locations tested positive for Merkel cell polyomavirus sequences by PCR, including all of his common warts (4/4), half of his carcinoma in situ lesions (3/6), and 2 of his 3 seborrheic keratoses...
  68. pmc The ND10 component promyelocytic leukemia protein relocates to human papillomavirus type 1 E4 intranuclear inclusion bodies in cultured keratinocytes and in warts
    Sally Roberts
    Cancer Research UK Institute for Cancer Studies, University of Birmingham, United Kingdom
    J Virol 77:673-84. 2003
    ..Analysis of HPV1-induced warts demonstrated that nuclear PML-E4 inclusions were present in productively infected keratinocytes, indicating that ..
  69. ncbi High viral load of human wart-associated papillomaviruses (PV) but not beta-PV in cutaneous warts independent of immunosuppression
    A Kohler
    Charite, Department of Dermatology, Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 161:528-35. 2009
    A broad spectrum of human papillomaviruses (HPV) has been detected in warts from immunocompetent patients and a much more diverse range from immunosuppressed organ transplant recipients (OTR).
  70. ncbi Topical treatments for cutaneous warts
    S Gibbs
    Ipswich Hospital NHS Trust, Department of Dermatology, Ipswich, UK IP4 5PD
    Cochrane Database Syst Rev 3:CD001781. 2006
    Viral warts are common and usually harmless but very troublesome. A very wide range of local treatments are used.
  71. ncbi Guidelines for the management of cutaneous warts
    J C Sterling
    Department of Dermatology, Addenbrooke s Hospital Cambridge, UK
    Br J Dermatol 144:4-11. 2001
    These guidelines for the management of cutaneous warts have been prepared for dermatologists on behalf of the British Association of Dermatologists...
  72. ncbi Topical formic acid puncture technique for the treatment of common warts
    R M Bhat
    Department of Dermatology and Venereology, Father Muller s Medical College Hospital, Kankanady, Mangalore, Karnataka State, India
    Int J Dermatol 40:415-9. 2001
    b>Warts are a common chronic skin disorder that can be cosmetically disfiguring and, depending on the location, cause inhibition of function...
  73. ncbi Comparison of combination of cimetidine and levamisole with cimetidine alone in the treatment of recalcitrant warts
    D Parsad
    Department of Dermatology, Himalayan Institute of Medical Sciences, Jolly Grant, Dehradun, India
    Australas J Dermatol 40:93-5. 1999
    Various immunomodulating agents have been used in the treatment of recalcitrant warts, but none is uniformly effective. Drugs like cimetidine and levamisole have been tried with varying success rates...
  74. ncbi Imiquimod for plantar and periungual warts
    J D Sparling
    Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Cutis 68:397-9. 2001
    Plantar and periungual warts are notoriously difficult to eradicate. Two cases of nongenital warts in teenage girls are presented...
  75. ncbi Pain induced by photodynamic therapy of warts
    I M Stender
    Department of Dermatology, H S Copenhagen University, Copenhagen, Denmark
    Photodermatol Photoimmunol Photomed 22:304-9. 2006
    ..Pain during and after light exposure is a well-known adverse advent that may be a limiting factor for treatment, particularly, in viral warts.
  76. pmc Degenerate and nested PCR: a highly sensitive and specific method for detection of human papillomavirus infection in cutaneous warts
    C A Harwood
    Department of Academic Dermatology, Royal Hospitals NHS Trust, London, United Kingdom
    J Clin Microbiol 37:3545-55. 1999
    ..Immunosuppressed renal transplant recipients have an increased incidence of viral warts and nonmelanoma skin cancer, and the presence of HPV DNA in these lesions, especially types associated with the ..
  77. ncbi Effect of highly active antiretroviral therapy on frequency of oral warts
    D Greenspan
    Department of Stomatology and the Oral AIDS Center, University of California at San Francisco, San Francisco, CA, USA
    Lancet 357:1411-2. 2001
    ..There was an increase in salivary-gland disease and a striking increase in warts: three-fold for patients on antiretroviral therapy and six-fold for those on HAART (p=0.01)...
  78. ncbi Cutaneous warts: an evidence-based approach to therapy
    Rocky Bacelieri
    Southern Illinois University School of Medicine, Springfield, Illinois, USA
    Am Fam Physician 72:647-52. 2005
    Cutaneous warts are a common presenting complaint in children and adolescents. Common, plantar, or flat warts are cutaneous manifestations of the human papillomavirus. The treatment of warts poses a therapeutic challenge for physicians...
  79. ncbi Photodynamic therapy with topical delta-aminolaevulinic acid for the treatment of plantar warts
    G Fabbrocini
    Dipartimento di Biologia e Patologia Cellulare e Molecolare, University of Naples Federico II, Naples, Italy
    J Photochem Photobiol B 61:30-4. 2001
    Treatments currently employed for plantar warts are often painful (electrosurgery, cryotherapy) and not always effective (keratolytic agents)...
  80. ncbi Intralesional immunotherapy of warts with mumps, Candida, and Trichophyton skin test antigens: a single-blinded, randomized, and controlled trial
    Thomas D Horn
    Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    Arch Dermatol 141:589-94. 2005
    b>Warts occur commonly in humans. Destructive modalities are generally the first physician-administered therapy. Other treatment options include immunotherapy...
  81. ncbi Autoimplantation therapy for multiple warts
    V Shivakumar
    Department of Dermatology, Sri Devaraj Urs Medical College, Tamaka, Kolar, India
    Indian J Dermatol Venereol Leprol 75:593-5. 2009
    In the treatment of multiple warts, there is no single treatment that is 100% effective and different modalities of treatment need to be combined.
  82. pmc Combination of qualitative and quantitative methods for developing a new Health Related Quality of Life measure for patients with anogenital warts
    Xavier Badia
    Health Outcomes Research Europe Group, Avda Diagonal, 618 1 C D, 08021 Barcelona, Spain
    Health Qual Life Outcomes 3:24. 2005
    Anogenital warts are the most easily recognized sign of genital Human Papilloma Virus infection...
  83. ncbi Viral warts in organ transplant recipients: new aspects in therapy
    T Schmook
    Department of Dermatology, University Hospital Charite, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Br J Dermatol 149:20-4. 2003
    ..The majority of transplant recipients will develop warts induced by human papillomavirus (HPV)...
  84. ncbi B-cell lymphoma in a patient with WHIM syndrome
    K M Chae
    Department of Dermatology, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612-3864, USA
    J Am Acad Dermatol 44:124-8. 2001
    WHIM syndrome is a rare congenital familial syndrome consisting of warts, hypogammaglobulinemia, infections, and myelokathexis. We describe a 30-year-old man with WHIM syndrome, in whom red dermal facial nodules developed...
  85. ncbi Photodynamic therapy: new treatment for therapy-resistant plantar warts
    Careen A Schroeter
    Department of Laser Therapy, Medical Centre Maastricht, Maastricht, The Netherlands
    Dermatol Surg 31:71-5. 2005
    ..Various treatment modalities have been previously used and are still in current use. The problem remains in the degree of response to these treatments and the side effects associated with them...
  86. ncbi Successful treatment of topical photodynamic therapy using 5-aminolevulinic acid for plane warts
    D Mizuki
    Br J Dermatol 149:1087-8. 2003
  87. ncbi Verrucae vulgares: flashlamp-pumped pulsed dye laser treatment in 134 patients
    Daisy Kopera
    Department of Dermatology, University of Graz, Graz, Austria
    Int J Dermatol 42:905-8. 2003
    ..Thus, a study was designed to evaluate the efficacy of a flashlamp-pumped pulsed dye laser (FPDL) in the treatment of verrucae vulgares...
  88. ncbi Imiquimod: a new immune response modifier for the treatment of external genital warts and other diseases in dermatology
    Brian Berman
    University of Miami, Miami, FL, USA
    Int J Dermatol 41:7-11. 2002
  89. ncbi Altered leukocyte response to CXCL12 in patients with warts hypogammaglobulinemia, infections, myelokathexis (WHIM) syndrome
    Anna Virginia Gulino
    Clinica Pediatrica, Universita di Brescia, c o Spedali Civili, 25 123 Brescia, Italy
    Blood 104:444-52. 2004
    ..truncating mutations in the CXCR4 intracellular tail cause a rare genetic disease known as WHIM syndrome (warts, hypogammaglobulinemia, infections, myelokathexis), whose pathophysiology remains unclear...
  90. ncbi Acral melanoma simulating warts: dermoscopic clues to prevent missing a melanoma
    Joan Dalmau
    Department of Dermatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Dermatol Surg 32:1072-8. 2006
    ..In the Caucasian population health care providers often misdiagnose acral melanoma, and this is the cause of inadequate treatments. Clinical and dermoscopic clues can be easily recognized, which help to prevent missing a melanoma...
  91. pmc Local treatments for cutaneous warts: systematic review
    Sam Gibbs
    Department of Dermatology, Ipswich Hospital NHS Trust, Ipswich IP4 5PD
    BMJ 325:461. 2002
    To assess the evidence for the efficacy of local treatments for cutaneous warts.
  92. ncbi Recalcitrant warts, associated with natural killer cell dysfunction, treated with systemic IFN-alpha
    Natalie N Cac
    J Allergy Clin Immunol 118:526-8. 2006
  93. ncbi WHIM syndrome, an autosomal dominant disorder: clinical, hematological, and molecular studies
    R J Gorlin
    Department of Oral Sciences, University of Minnesota Health Sciences Center, Minneapolis, Minnesota 55455, USA
    Am J Med Genet 91:368-76. 2000
    The acronym WHIM refers to Warts, Hypogammaglobulinemia, Infections, and Myelokathexis. The latter refers to the retention of white cells in the marrow, which becomes hypercellular...
  94. ncbi Randomized, comparative trial on the sustained efficacy of topical imiquimod 5% cream versus conventional ablative methods in external anogenital warts
    Helmut Schöfer
    Department of Dermatology and Venerology, University Hospital, J W Goethe University Theodor Stern Kai 7, D 60596 Frankfurt M, Germany
    Eur J Dermatol 16:642-8. 2006
    Conventional ablative treatments for external anogenital warts are affected by high recurrence rates. This study compared sustained clearance after ablation vs. treatment with imiquimod 5% cream vs. the combination of both methods...
  95. ncbi Photodynamic therapy with 5-aminolaevulinic acid or placebo for recalcitrant foot and hand warts: randomised double-blind trial
    I M Stender
    Department of Dermatology, Bispebjerg Hospital, Copenhagen, Denmark
    Lancet 355:963-6. 2000
    ..with topical 5-aminolaevulinic acid (ALA) followed by irradiation with incoherent light (ALA-PDT) for recalcitrant warts have had beneficial results...
  96. pmc Very late onset small intestinal B cell lymphoma associated with primary intestinal lymphangiectasia and diffuse cutaneous warts
    Y Bouhnik
    Department of Gastroenterology and Hepatology, Hopital Lariboisiere, Paris, France
    Gut 47:296-300. 2000
    ..They presented with a longstanding history of fluctuating protein losing enteropathy, multiple cutaneous plane warts, and markedly dilated mucosal and submucosal lymphatic channels in duodenal biopsies...
  97. ncbi Photodynamic therapy with 20% aminolevulinic acid for the treatment of recalcitrant viral warts in an Asian population
    Yi Shi Wang
    Division of Dermatology, Changi General Hospital, Singapore
    Int J Dermatol 46:1180-4. 2007
    ..It is well established for the treatment of actinic keratoses and superficial nonmelanoma skin cancers. Some studies have reported good efficacy when using PDT to treat viral warts in the Western population.
  98. ncbi Photodynamic therapy using light-emitting diodes for the treatment of viral warts
    Akiko Ohtsuki
    Department of Dermatology, Juntendo University School of Medicine, Tokyo, Japan
    J Dermatol 36:525-8. 2009
    ..Further, some studies have reported good efficacy when using photodynamic therapy to treat viral warts. The light-emitting diode is an incoherent, narrow-spectrum light source...
  99. ncbi Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contagiosum
    U R Hengge
    Department of Dermatology, Venereology and Allergology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Br J Dermatol 143:1026-31. 2000
    Despite numerous therapeutic options the treatment of common warts and molluscum contagiosum remains unsatisfactory for both patients and physicians...
  100. ncbi A genotype distribution of human papillomaviruses detected by polymerase chain reaction and direct sequencing analysis in a large sample of common warts in Japan
    Keisuke Hagiwara
    Department of Dermatology, School of Medicine, University of the Ryukyus, Okinawa, Japan
    J Med Virol 77:107-12. 2005
    ..There have been no large-scale epidemiological studies of human papillomavirus (HPV) genotype distribution of common warts in Japan...
  101. ncbi Recurrent CXCR4 sequence variation in a girl with WHIM syndrome
    Krisztina Alapi
    Department of Infectious and Pediatric Immunology, Medical and Health Science Centre, University of Debrecen, Debrecen, Hungary
    Eur J Haematol 78:86-8. 2007
    WHIM (warts-hypogammaglobulinemia-infections-myelokathexis) syndrome is a recently described primary immunodeficiency disorder caused by mutation of the CXCR4 chemokine receptor gene. We report here of a 6...

Research Grants64

  1. Regulation of Human Papillomavirus Replication via Cell Signaling Pathways
    ANASTACIA GRIEGO; Fiscal Year: 2013
    ..of infecting mucosal and cutaneous epithelium, the majority of these types cause only benign lesions such as warts. HPVs are designated as oncogenic based on the ability of a specific viral genotype to cause transformation in the ..
  2. RRSS #08: Evaluating Prevalence HPV Infection Among Head and Neck Cancer Patients
    Dennis M Deapen; Fiscal Year: 2009
    ..Low-risk types are associated with benign lesions such as warts, while infections with high-risk types progress to malignant lesions...
  3. PKC/PKA Regulation in Prostate Cancer by SSeCKS/Gravin/AKAP12
    Irwin H Gelman; Fiscal Year: 2013
    ..defects through the activation of RhoA and LIMK, and through the suppression of the mitotic exit network kinase, WARTS, and ii) Rb-dependent senescence by increasing reactive oxygen species (ROS) mediators such as p47phox...
  4. E2-Cellular Complexes in HPV Chromatin Transcription
    Cheng Ming Chiang; Fiscal Year: 2013
    ..by applicant): Human papillomaviruses (HPVs) are etiological agents for many human diseases, including genital warts, skin warts, cervical cancer, and certain types of head-and-neck and skin cancers...
  5. Control of cell number in developing retina
    Duojia Pan; Fiscal Year: 2013
    ..us to delineate a Hippo kinase cascade comprised of the Ste20-like kinase Hippo (Hpo), the NDR family kinase Warts (Wts), and the transcriptional co activator Yorkie (Yki)...
  6. MECHANISMS OF HUMAN PAPILLOMAVIRUS DNA REPLICATION
    Louise T Chow; Fiscal Year: 2013
    ..by these extremely prevalent pathogens can result in epithelial hyperproliferation, including ano-genital warts and laryngeal papillomas...
  7. Steroid-Dependent Changes in the Yorkie Interactome
    Alexey Veraksa; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The Hippo (or alvador/Warts/Hippo, SWH) pathway is a well-conserved metazoan signaling cascade that restricts organ size in the fruit fly Drosophila melanogaster and limits tumorigenesis in mammals...
  8. Oncogenic Human Papillomavirus Protein Network
    PETER M contact HOWLEY; Fiscal Year: 2010
    ..The low-risk HPVs, such as HPV6 and HPV44 associated with venereal warts, are in species 10...
  9. Molecular Mechanisms of Myelokathexis
    Andrew Aprikyan; Fiscal Year: 2009
    ..In some but not all patients, there is an association of Warts, Hypogammaglobulinemia, and recurrent bronchopulmonary Infections with Myelokathexis (W.H.I.M. syndrome)...
  10. HPV Knowledge Awareness and Vaccine Acceptability among Inner City Black Males
    SHERRIE LEE WALLINGTON; Fiscal Year: 2013
    ..4 per 100,000 females, among the highest in the nation. HPV has been associated with anogenital warts and cancers of the cervix, penis, and anus, and also with vulvar, vaginal, and oropharyngeal cancers...
  11. Growth regulation by the Fat signaling pathway
    Kenneth D Irvine; Fiscal Year: 2013
    ..identified positive regulators of Fat-Hippo signlaing, and the transmission of Fat signaling to the kinase Warts. These studies will employ a combination of biochemical, cell biological, and genetic techniques in Drosophila...
  12. HPV CAPSID ANTIBODIES
    Denise A Galloway; Fiscal Year: 2013
    ..Human papillomaviruses (HPVs) are the most common sexually transmitted viral infections, resulting in genital warts, intraepithelial neoplasia and anogenital cancers...
  13. Genetic Susceptibility to Papilloma-induced Voice Disturbance
    FARREL JOEL BUCHINSKY; Fiscal Year: 2012
    ..organs and fall into two general classes: those causing cervical neoplasia;and those causing condylomata (genital warts)...
  14. HITCH: A Study of HPV Transmission in Young Couples
    Eduardo L Franco; Fiscal Year: 2013
    ..Most such infections are not noticed or cause only external warts. Warts are difficult to treat and lead to social stigmatization. Some HPV infections may lead to cervical cancer...
  15. Development of a Primate Model for Genital Papillomavirus Infection
    Robert D Burk; Fiscal Year: 2010
    ..In addition to causing genital warts, persistent cervical infection with oncogenic alpha papillomaviruses can result in cervix cancer...
  16. Genetic Interaction Between the pRB and Warts Tumor Suppressor Pathways
    Brandon Nicolay; Fiscal Year: 2010
    ..Thus, the outcome of this study could demonstrate that targeted inhibition of activator E2Fs could prove to be a productive anticancer therapy. ..
  17. Optimizing HPV Vaccination: Parents, Providers and Pre-teen Boys
    JOAN ROBERTS CATES; Fiscal Year: 2013
    ..HPV causes genital warts and is associated with cervical, vaginal, vulvar, anal, penile, and throat cancers...
  18. Oral Mucosal Immunity in Vulnerable HIV Infected Populations
    Aaron Weinberg; Fiscal Year: 2013
    ..Projects 3 and 4 will share tissue isolated from oral warts and other oral mucosal complication associated with HIV to examine their protein and genomic profiles...
  19. Mother-Daughter Joint Decision Making to Obtain the HPV Vaccine
    Julia Lechuga; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The Human Papillomavirus (HPV) is a precursor of cervical cancer and genital warts. HPV strains, 16 and 18, are recognized as precursors of 70% of cervical cancers...
  20. Genetic Epidemiology of HPV Infection Outcome in Men
    Sadeep Shrestha; Fiscal Year: 2013
    ..are important in transmitting HPV to their female sexual partners along with the public health burden of genital warts and several cancers, understanding the natural history of HPV in men would benefit both men and women...
  21. Interactions between the stroma and progenitor cells during kidney development
    THOMAS JOSEPH CARROLL; Fiscal Year: 2013
    ..We hypothesize that Fat4 regulates differentiation of the progenitors by activating the Hippo/Warts pathway in a subset of progenitor cells...
  22. Cervical, Anal &Oral HPV Persistence/Adolescent Girls
    NICOLAS SCHLECHT; Fiscal Year: 2013
    ..HR] types present in >65% of cervical cancers), as well as HPV6 and 11 (associated with most genital warts), has the potential to reduce the burden of genital HPV and disease...
  23. Induction of genomic instability by HPV E6 and E7
    Jason J Chen; Fiscal Year: 2012
    ..Infection with human papillomaviruses (HPV) induces warts and is strongly associated with the development of cervical cancer...
  24. HTS Screening for Inhibitors of HPV 16 E6/Caspase 8 Binding
    Penelope J Duerksen-Hughes; Fiscal Year: 2013
    ..are best known for their ability to cause cervical and head and neck cancer, though they also cause sores and warts that do not lead to cancer...
  25. Cervical, Anal &Oral HPV Persistence/Adolescent Girls
    NICOLAS SCHLECHT; Fiscal Year: 2012
    ..high-risk types present in >65% of cervical cancers), as well as HPV6 and 11 (associated with most genital warts), has the potential to reduce the burden of genital HPV and disease...
  26. Characterizing the R8 cell subtype fate in Drosophila
    Brent S Wells; Fiscal Year: 2013
    ..Babo may then interact with the warts/melted bi-stable loop to maintain this fate...
  27. FUNCTION OF MERLIN, A DROSOPHILA NF2 GENE HOMOLOGUE
    Richard G Fehon; Fiscal Year: 2013
    ..3) Examine the role of signaling by the Hippo, Salvador, Warts pathway on regulating receptor abundance at the cell surface...
  28. Using Health Information Technology to Improve Delivery of HPV Vaccine
    Cynthia M Rand; Fiscal Year: 2013
    ..Delivering HPV vaccine to all young women will ultimately reduce their risk for cervical cancer and genital warts, and decrease their lifetime healthcare costs...
  29. Natural History of HPV Infection in Men: The HIM Study
    Anna R Giuliano; Fiscal Year: 2013
    ..HPV-related external genital lesions (EGLs) consist of two categories: condyloma (genital warts) and penile intraepithelial neoplasia (PIN)...
  30. Cell Competition in Development and Homeostasis
    Nicholas E Baker; Fiscal Year: 2013
    ..and to the hypothesis that ribosomal protein imbalances activate tumor suppressors of the Salvador-Hippo-Warts pathway to promote elimination of damaged cells...
  31. MOLECULAR DISSECTION OF TUMOR INVASION
    SCOTT A GOODE; Fiscal Year: 2010
    ..Three genes encoding signaling molecules, Warts (human Lats1/2), Mats (human Mobla), and Yorki (human Yap), are all implicated in human carcinogenesis...
  32. PATTERNING THE RETINA FOR COLOR VISION
    Claude Desplan; Fiscal Year: 2013
    ..This signal is then interpreted by a bistable loop between the Hippo/Warts tumor suppressor pathway and the growth regulator Melted...
  33. Fat-Dachsous signaling in growth control and planar cell polarity
    Seth S Blair; Fiscal Year: 2013
    ..pathway for controlling growth, cell death and patterning in developing organisms: that mediated by the Hippo and Warts protein kinases...
  34. Tailoring an Intervention with Parents in Rural Areas to Reduce HPV Transmission
    Tami Lynn Thomas; Fiscal Year: 2012
    ..7 billion healthcare dollars are spent each year for the treatment of HPV infection, genital warts, and cervical cancer...
  35. ROLE OF CELLULAR PROTEINS IN HPV TRANSCRIPTION
    Cheng Ming Chiang; Fiscal Year: 2004
    Human papillomaviruses (HPVs) cause a variety of human diseases including genital warts and cervical carcinomas...
  36. The Oral Microbiome in HIV-associated Oral Warts and Candidiasis
    Eugene J Leys; Fiscal Year: 2013
    ..Currently, the most common oral manifestations of HIV disease are oropharyngeal candidiasis (OPC) and oral warts. In addition, HPV-associated head and neck squamous cell carcinomas (HNSCC) are increased in HIV+ individuals and ..
  37. HUMAN PAPILLOMAVIRUS GENE EXPRESSION IN CERVICAL CANCER
    DAVID SMOTKIN; Fiscal Year: 1992
    ..It is proposed that: 1. HPV messenger RNA will be mapped and quantitated in benign warts and invasive tumors...
  38. Effect of HIV and immunosuppression on oral HPV persistence in the HAART era
    GYPSYAMBER D'SOUZA; Fiscal Year: 2013
    ..The prevalence of both oral warts (which is caused by HPV) and HPV-associated cancers have not decreased since the introduction of HAART...
  39. Development of immune assays for HPV-32
    Michael Hagensee; Fiscal Year: 2006
    ..of all HIV infected patients, and include oropharyngeal candidiasis (OPC), oral hairy leukoplakia (OHL) and oral warts caused by the mucosatropic human papillomavirus (HPV)...
  40. Atlanta Summer Institute in Biostatistics II
    Lance A Waller; Fiscal Year: 2013
    ..software to implement and illustrate the concepts and to derive substantive conclusions from actual data sets (warts and all) thereby training participants to use underlying concepts to drive their search for appropriate skills ..
  41. CMI TO HPV IN HIV INFECTED WOMEN & OUTCOME OF NEOPLASIA
    ANNA KADISH; Fiscal Year: 2000
    ..g., sexual activities, past history of STD or genital warts)...
  42. New Cellular Effectors of Human Papillomavirus E7 Activity
    Ann Roman; Fiscal Year: 2009
    ..Some HPVs cause the most prevalent benign viral sexually transmitted hyperproliferative disease, genital warts, and are referred to as low risk (LR) HPVs (e.g., HPV 6)...
  43. Strategies Against HPV Related Genital Diseases in Women
    Bradley Monk; Fiscal Year: 2006
    ..and effective in HPV related laryngeal papillomatosis, will be evaluated in patients with HPV induced genital warts in a randomized phase II trial...
  44. Participatory Research to Understand the Translation of HPV Vaccine Policy
    Andrew Sussman; Fiscal Year: 2009
    ..against 4 types of HPV infections, two which cause abnormal cervical dysplagia and two which cause genital warts. In the 15 months since the approval and the subsequent recommendation by the Advisory Committee on Immunization ..
  45. Oral Health Outcomes in Pediatric Transplant Recipients
    CAROLINE SHIBOSKI; Fiscal Year: 2004
    ..Oral health outcomes of interest include mucosal diseases (e.g., candidiasis, hairy leukoplakia, ulcers, warts, lip carcinoma, non-Hodgkin's lymphoma, and Kaposi's sarcoma (KS), gingival enlargement (GE), and dental needs...
  46. VIVO OF PAPILLOMAVIRUS TRANSFORMING GENES
    Janet Brandsma; Fiscal Year: 1992
    ..rabbit papillomavirus (CRPV) system, the system in which malignant progression and immune response to PV-induced warts has been best documented. The CRPV model closely mimics the situation for HPV-induced disease...
  47. CANCER CHEMOPREVENTION--ROLE OF INFECTION/IMMUNITY
    Charles Loprinzi; Fiscal Year: 2003
    ..imiquimod, and immunomodulatory agent which has proven to be safe and effective for the treatment of genital warts. This trial will be conducted on patients with recurrent and/or high-grade cervical intraepithelial neoplasia (CIN)..
  48. Using Message Framing to Promote HPV Vaccination
    MARY GEREND; Fiscal Year: 2009
    ..The vaccine protects against infection by four HPV types responsible for over 90% of all genital warts and 70% of all cervical cancers...
  49. IMMUNE MECHANISMS OF HUMAN PAPILLOMAVIRUS
    Tim Mosmann; Fiscal Year: 2003
    Human Papillomavirus is a widespread pathogen that causes different types of warts, and is also the main cause of cervical cancer. In many patients, the immune system limits the spread of infection, but does not destroy the wart...
  50. The Mechanisms of Human Papillomavirus Pathogenicity
    Ann Roman; Fiscal Year: 2006
    ..is the causative agent of the most prevalent viral sexually transmitted disease, benign hyperproliferative genital warts. Over a million new cases of this disease are diagnosed annually and almost four billion dollars in US health care ..
  51. Topical use of TEAC to treat cutaneous viral infection
    David Osborne; Fiscal Year: 2006
    unreadable] DESCRIPTION (provided by applicant): Common warts, those found on the hands, tops of the feet, and sometimes on the face, arms and legs, may persist for years and may increase in size and number...
  52. Topical use of TEAC to treat cutaneous viral infection
    Karl Beutner; Fiscal Year: 2004
    Mucocutaneous viral infections including human papillomavirus (HPV)-induced warts have a significant impact on the world population...
  53. HIV ASSOCIATED MALIGNANCIES TRAINING--MALAWI
    Chris Beyrer; Fiscal Year: 2000
    ..g.,the prevalence of syphilis is 11%, Trichomoniasis is 24%, genital ulcers is 3.4%, and genital warts is 2.5%...
  54. MATERNAL RISK FACTORS FOR J ORRP IN DENMARK
    Keerti Shah; Fiscal Year: 2001
    ..is caused by perinatal mother-to-child transmission of HPV types 6 and 11 which are also responsible for genital warts. The proposed population-based, retrospective, cohort study plans to analyze data in Danish National Registries to ..
  55. Transcriptional regulation of growth downstream of tumor suppressor pathways
    Hyangyee Oh; Fiscal Year: 2009
    ..These studies have revealed that growth regulation by Fat/Hippo/Merlin pathways is converged into a kinase called Warts, another tumor suppressor...
  56. GENITAL HERPES/GENITAL WARTS: REPRESENTATIONS & COPING
    Mary Keller; Fiscal Year: 1991
    ..have reached epidemic proportions in the United States; two of the most common STDS are genital herpes and genital warts. Clinicians have identified significant psychological distress in patients with these diseases...
  57. RNA Analysis of HPV Viral Loads
    Laura Koutsky; Fiscal Year: 2005
    ..primarily HPV 16 and 18) are causally related to the development of cervical cancer, and most genital warts are positive for HPV 6...
  58. TECHNOLOGY FOR THERAPEUTICS AGAINST CERVICAL CARCINOMA
    Tanya Sandrock; Fiscal Year: 2000
    ..Low-risk HPV types are associated with common warts. Two gene products, E6 and E7, are primarily responsible for HPV-related cellular transformation...
  59. IMMUNE RESPONSES TO HPVS INVOLVED IN GENITAL NEOPLASIA
    Steven Jenison; Fiscal Year: 1993
    ..with biologically distinct diseases of the female genital tract: HPV6b is most often found in common genital warts (condylomata acuminata), and HPV16 and HPV18 are frequently associated with uterine cervical dysplasia and ..
  60. Natural History of HPV Infections in Men
    Laura Koutsky; Fiscal Year: 2009
    ..and levels of HPV DNA, HPV type-specific seroconversion, duration of antibodies, and development of genital warts. Our long-term goal is development of cost-effective approaches to the prevention of HPV-related cancers...
  61. Modulation of a novel cell cycle checkpoint by the HPV oncogene E6
    Jason Chen; Fiscal Year: 2009
    ..Infection with human papillomaviruses (HPV) induces warts and is strongly associated with the development of cervical cancer...
  62. MECHANISM OF HPV E6 MEDIATED UBIQUITINATION OF P53
    Peter Howley; Fiscal Year: 1999
    ..One group, including HPV-6 and HPV-1 l, is generally associated with benign anogenital warts that infrequently progress to cancer and is considered "low risk...
  63. Detecting Integrated HPV DNA in Immunocompromised Women
    PHILLIP MOEN; Fiscal Year: 2005
    Human papillomavirus (HPV) infection is the cause of virtually all genital warts (condyloma), and cervical and anal cancers...
  64. Cellular Regulation of Papillomavirus E1 Function
    VAN WILSON; Fiscal Year: 2007
    ..unreadable] DESCRIPTION (provided by applicant): Papillomaviruses are the causative agents of cutaneous and genital warts. Infection with certain subtypes of genital papillomaviruses is the primary risk factor for cervical cancer...