Genomes and Genes
Summary: An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)
Publications218 found, 100 shown here
- [Infections caused by Varicella Zoster virus in children with cancer aged less than 15 years old]Isabel Folatre
Instituto de Hematología R Virchow, Instituto de Pediatria, Facultad de Medicina, Universidad Austral de Chile, Casilla 567 Valdivia
Rev Med Chil 131:759-64. 2003..Infections caused by Varicella Zoster virus in children with cancer have a high rate of complications and mortality...
- [Varicella-zoster virus infections. 1: Chickenpox and shingles. Treatment and prevention]S W Wassilew
Dermatologische Klinik, Klinikum Krefeld
MMW Fortschr Med . 2006
- Risk of herpes zoster in patients with rheumatoid arthritis treated with anti-TNF-alpha agentsAnja Strangfeld
Epidemiology Unit, German Rheumatism Research Center, Chariteplatz 1, 10117 Berlin, Germany
JAMA 301:737-44. 2009..The risk of bacterial infection is increased in patients treated with drugs that inhibit tumor necrosis factor alpha (TNF-alpha). Little is known about the reactivation of latent viral infections during treatment with TNF-alpha inhibitors...
- Varicella-zoster virus transfer to skin by T Cells and modulation of viral replication by epidermal cell interferon-alphaChia Chi Ku
Department of Pediatrics, Stanford University, School of Medicine, Stanford, CA 94305, USA
J Exp Med 200:917-25. 2004..Modulation of VZV replication by cutaneous innate immunity may avoid an incapacitating infection of the host that would limit opportunities for VZV transmission...
- The role of sympathetic nerve blocks in herpes zoster and postherpetic neuralgiaC L Wu
The Johns Hopkins Hospital, Department of Anesthesiology and Critical Care Medicine, Division of Pain Medicine, 550 N Broadway, Suite 301, Baltimore, MD 21205, USA
Pain 87:121-9. 2000The most common complication of herpes zoster in immunocompetent patients is postherpetic neuralgia (PHN)...
- Predictors of pain intensity and persistence in a prospective Italian cohort of patients with herpes zoster: relevance of smoking, trauma and antiviral therapyGiustino Parruti
Infectious Disease Unit, Pescara General Hospital, Pescara, Italy
BMC Med 8:58. 2010b>Herpes zoster (HZ) is a common disease, characterized by rash-associated localized pain. Its main complication, post-herpetic neuralgia (PHN), is difficult to treat and may last for months to years in the wake of rash resolution...
- Herpes zoster risk factors in a national cohort of veterans with rheumatoid arthritisJay R McDonald
St Louis Veterans Affairs Medical Center, St Louis, Missouri 63106, USA
Clin Infect Dis 48:1364-71. 2009b>Herpes zoster occurs more commonly in patients taking immunosuppressive medications, although the risk associated with different medications is poorly understood.
- Varicella-zoster virusA M Arvin
Department of Pediatrics, Stanford University School of Medicine, California 94305 5119, USA
Clin Microbiol Rev 9:361-81. 1996Varicella-zoster virus (VZV) is a ubiquitous human alphaherpesvirus that causes varicella (chicken pox) and herpes zoster (shingles)...
- Varicella-zoster virus-specific immune responses to herpes zoster in elderly participants in a trial of a clinically effective zoster vaccineAdriana Weinberg
University of Colorado Denver, Denver, CO, USA
J Infect Dis 200:1068-77. 2009..were to evaluate the association between varicella-zoster virus (VZV)-specific humoral and cell-mediated immunity (CMI) to herpes zoster (HZ) and protection against HZ morbidity and to compare immune responses to HZ and zoster vaccine.
- Herpes zoster and postherpetic neuralgia: optimizing management in the elderly patientRobert W Johnson
Bristol Royal Infirmary and University of Bristol, Bristol, United Kingdom
Drugs Aging 25:991-1006. 2008b>Herpes zoster (HZ) results from reactivation of varicella-zoster virus (VZV) that has been persistent and clinically dormant in spinal ganglia or cranial sensory nerves since primary infection with VZV...
- Prevalence of postherpetic neuralgia after a first episode of herpes zoster: prospective study with long term follow upS Helgason
Arbaer Health Care Centre, IS 110 Reykjavik, Iceland S Helgason
BMJ 321:794-6. 2000To estimate the frequency, duration, and clinical importance of postherpetic neuralgia after a single episode of herpes zoster.
- Advances in the understanding of the pathogenesis and epidemiology of herpes zosterAnne A Gershon
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
J Clin Virol 48:S2-7. 2010..root ganglia during varicella and, when reactivated, travels along the sensory nerve axons to cause shingles (herpes zoster [HZ])...
- Influence of systemic immune and cytokine responses during the acute phase of zoster on the development of postherpetic neuralgiaSheng Mei Zhu
Department of Anesthesiology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China
J Zhejiang Univ Sci B 10:625-30. 2009Postherpetic neuralgia (PHN) is a severe sequela of herpes zoster (HZ). Until now, only age and pain severity were considered predisposing factors for the development of PHN...
- [Evaluation of literature quality of acupuncture for treatment of herpes zoster and approach to the laws of treatment]Wei Na Peng
Section of Acupuncture, Guang anmen Hospital, China Academy of Chinese Medical Sciences, Beijing 100053, China
Zhongguo Zhen Jiu 28:147-50. 2008To assess the quality of literature of clinical studies on acupuncture in treatment of herpes zoster.
- Acupuncture in acute herpes zoster pain therapy (ACUZoster) - design and protocol of a randomised controlled trialJohannes Fleckenstein
Multidisciplinary Pain Centre, Department of Anaesthesiology, University of Munich, Munich, Germany
BMC Complement Altern Med 9:31. 2009Acute herpes zoster is a prevalent condition. One of its major symptoms is pain, which can highly influence patient's quality of life. Pain therapy is limited...
- Herpes zoster during treatment with arsenic trioxideDouglas J Lanska
Ann Hematol 83:408. 2004
- Clinical and genetic risk factors of herpes zoster in patients with systemic lupus erythematosusTae-young Kang
Hospital for Rheumatic Diseases, Hanyang University Hospital, 17 Haengdang-dong, Seong Dong-ku, Seoul 133-792, Republic of Korea
Rheumatol Int 25:97-102. 2005OBJECTIVE: The aim of this study was to determine the clinical and genetic risk factors that influence herpes zoster occurrence in patients with systemic lupus erythematosus (SLE)...
- Varicella zoster virus: review of its managementM B Mustafa
Oral Medicine Section, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Khartoum, Khartoum, Sudan
J Oral Pathol Med 38:673-88. 2009..The first choice of any of these medications should be guided by the patient's medical health, the likely adverse effects of the drug and the patient's preference...
- Herpes zoster and postherpetic neuralgia: past, present and futureGary J Bennett
Department of Anesthesia, Faculty of Dentistry, and The Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
Pain Res Manag 14:275-82. 2009..Data from recent work in virology, neuroanatomy and epidemiology are reviewed, as is work using varicella-zoster virus-infected animals. The recent data largely confirm Hope-Simpson's hypothesis and extend it significantly...
- Epidemiological features and costs of herpes zoster in Taiwan: a national study 2000 to 2006Jaw Shyang Jih
Department of Dermatology, National Yang Ming University, Department of Dermatology, Taipei Veterans General Hospital, Taipei, Taiwan
Acta Derm Venereol 89:612-6. 2009To analyse the epidemiological characteristics and related costs of herpes zoster in Taiwan, a nationally representative cohort of 1,000,000 individuals from the National Health Insurance register was followed up from 2000 to 2006 and ..
- Herpes zoster overview: natural history and incidenceBethany A Weaver
Armor Correctional Health Services in Tampa, Fla, USA
J Am Osteopath Assoc 109:S2-6. 2009..The primary VZV infection, known as chickenpox, typically occurs during childhood. Herpes zoster infection results later in life from reactivation of VZV in the dorsal root ganglia...
- Pure motor Herpes Zoster induced brachial plexopathyA Ismail
Department of Neurology, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
J Neurol 256:1343-5. 2009Brachial plexus neuritis in the presence of herpes zoster infection is uncommon...
- National survey of primary care physicians regarding herpes zoster and the herpes zoster vaccineLaura P Hurley
Department of General Internal Medicine, University of Colorado at Denver and Health Sciences Center, The Children s Hospital, Denver, Colorado, USA
J Infect Dis 197:S216-23. 2008This study describes physicians' perception of burden associated with herpes zoster (HZ) and postherpetic neuralgia (PHN), intentions for recommending the HZ vaccine, and perceived barriers to vaccination.
- Mechanisms of pain and itch caused by herpes zoster (shingles)Anne Louise Oaklander
Departments of Neurology and Pathology, Massachusetts General Hospital, Harvard Medical School, 275 Charles Street, Boston, MA 02114, USA
J Pain 9:S10-8. 2008..Further human study, by electrophysiological recording, by structural and functional imaging, and by autopsy, should continue to provide much-needed insights...
- [Systematic assessment of acupuncture for treatment of herpes zoster in domestic clinical studies]Xian Min Yu
Acupuncture Department, Yueyang Hospital of Integrated TCM and Western Medicine Affiliated to Shanghai University of TCM, China
Zhongguo Zhen Jiu 27:536-40. 2007To assess the effectiveness of acupuncture for treatment of herpes zoster.
- Diabetes as a risk factor for herpes zoster infection: results of a population-based study in IsraelA D Heymann
Medical Division, Maccabi Healthcare Services, 27 HaMered St, Tel Aviv, 68125, Israel
Infection 36:226-30. 2008..by impaired cell-mediated immunity, which potentially may increase the risk for infectious diseases, including herpes zoster (HZ). However, data on the relation between DM and HZ are scarce...
- Estimating the number needed to vaccinate to prevent herpes zoster-related disease, health care resource use and mortalityMarc Brisson
Départemente de médecine sociale et préventive, Universite Laval, Quebec, QC
Can J Public Health 99:383-6. 2008A clinical trial has shown that a live-attenuated varicella-zoster virus vaccine is effective against herpes zoster (HZ) and post-herpetic neuralgia (PHN)...
- Herpes zoster and postherpetic neuralgia: diagnosis and therapeutic considerationsMario Roxas
Thorne Research, PO Box 25, Dover, ID 83825, USA
Altern Med Rev 11:102-13. 2006b>Herpes zoster (HZ), also known as shingles, is a painful vesicular rash resulting from reactivation of the virus that also causes chickenpox - Varicella zoster virus (VZV). Typically, the rash runs its course in a matter of 4-5 weeks...
- A randomized, placebo-controlled trial of oxycodone and of gabapentin for acute pain in herpes zosterRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
Pain 142:209-17. 2009Although acute pain in patients with herpes zoster can be severe and has a substantial impact on health-related quality of life, there have been no randomized clinical trials of oral medications specifically for its ongoing treatment...
- Granuloma annulare on herpes zoster scars in a Hodgkin's disease patient following autologous peripheral stem cell transplantationH E Sanli
Department of Dermatology, Ankara University School of Medicine, Ankara, Turkey
J Eur Acad Dermatol Venereol 20:314-7. 2006Various cutaneous lesions including granulomatous reactions may occur at sites of resolved herpes zoster infection...
- The incidence of recurrent herpes simplex and herpes zoster infection during treatment with arsenic trioxideKeyvan Nouri
Department of Dermatology and Cutaneous Surgery, University of Miami, Miller School of Medicine, Miami, Florida, USA
J Drugs Dermatol 5:182-5. 2006..In this report, we discuss the effects of arsenic on immune system, and suggest arsenic compounds as a possible predisposing factor for viral reactivation in these patients...
- Herpes zoster in immunocompromised patients: incidence, timing, and risk factorsPeter K Wung
Johns Hopkins University School of Medicine, Johns Hopkins University, Baltimore, MD, USA
Am J Med 118:1416. 2005PURPOSE: To evaluate the risk factors for herpes zoster as well as the incidence and timing of this complication in patients who were treated with immunosuppression because of active Wegener's granulomatosis...
- Varicella-zoster virus-specific immune responses in elderly recipients of a herpes zoster vaccineM J Levin
University of Colorado Health Sciences Center, Denver, Colorado, USA
J Infect Dis 197:825-35. 2008..The trial included an immunology substudy to determine the relationship of VZV-specific immune responses to vaccination and clinical outcome...
- A single dose of gabapentin reduces acute pain and allodynia in patients with herpes zosterJames D Berry
UCSF Pain Clinical Research Center, Department of Neurology, University of California, San Francisco, CA, USA
Neurology 65:444-7. 2005..study measured the effect of a single dose of oral gabapentin (900 mg) on pain and allodynia associated with herpes zoster. Pain severity decreased by 66% with gabapentin compared to 33% with placebo...
- Efficacy of intravenous magnesium in neuropathic painS Brill
Department of Anaesthetics and Pain Management, University Hospital Lewisham, Lewisham High Street, London SE13 6LH, UK
Br J Anaesth 89:711-4. 2002BACKGROUND: Postherpetic neuralgia is a complication of acute herpes zoster characterized by severe pain and paraesthesia in the skin area affected by the initial infection...
- Herpes zoster in the immunocompetent patient: management of post-herpetic neuralgiaRobert W Johnson
Pain Management Clinic, University of Bristol and Bristol Royal Infirmary, Bristol, UK
Herpes 10:38-45. 2003Post-herpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ, shingles), particularly in the elderly and those with severe acute phase symptoms...
- Spinal cord stimulation in postherpetic neuralgia and in acute herpes zoster painHenning Harke
Department of Anesthesia and Pain Therapy, Klinikum Krefeld, Krefeld, Germany
Anesth Analg 94:694-700; table of contents. 2002..In addition, four patients with acute herpes zoster (HZ) pain were studied simultaneously...
- Comparative study of transfer factor and acyclovir in the treatment of herpes zosterS Estrada-Parra
Department of Immunology, National School of Biological Sciences, National Polytechnic Institute, Prol Carpio y Plan de Ayala, Mexico, D F
Int J Immunopharmacol 20:521-35. 1998..of varicella herpes virus (VHV), latent in individuals who have previously suffered varicella, gives rise to herpes zoster and in some cases leads to a sequela of post herpetic neuritis with severe pain which is refractory to ..
- The impact of herpes zoster and postherpetic neuralgia on health-related quality of life: a prospective studyMelanie Drolet
Unité de recherche en santé des populations, Centre Hospitalier Affilie Universitaire De Quebec, Quebec, Que
CMAJ 182:1731-6. 2010Vaccination against herpes zoster is being considered in many countries. We conducted a multicentre prospective study to describe the impact of herpes zoster and postherpetic neuralgia on health-related quality of life.
- Wet cupping therapy for treatment of herpes zoster: a systematic review of randomized controlled trialsHuijuan Cao
Beijing University of Chinese Medicine
Altern Ther Health Med 16:48-54. 2010Wet cupping is a traditional Chinese medicine therapy commonly used in treating herpes zoster in China, and clinical studies have shown that wet cupping may have beneficial effect on herpes zoster compared with Western medication.
- Increased risk of Guillain-Barré Syndrome following recent herpes zoster: a population-based study across TaiwanJiunn Horng Kang
Departments of 1Physical Medicine and Rehabilitation and 2Neurology, 3Neuroscience Research Center, and 4School of Health Care Administration, Taipei Medical University, Taipei, Taiwan
Clin Infect Dis 51:525-30. 2010Guillain-Barré syndrome (GBS) has been sporadically reported to be associated with herpes zoster reactivation. However, the risk for developing GBS after herpes zoster reactivation remains unknown...
- Zoster vaccine (Zostavax): a review of its use in preventing herpes zoster and postherpetic neuralgia in older adultsMark Sanford
Adis, a Wolters Kluwer Business, Auckland, New Zealand
Drugs Aging 27:159-76. 2010Individuals who have been infected with varicella zoster virus (VZV) are at risk for developing herpes zoster and this risk appears to be related to a decline in VZV-specific cell-mediated immunity (CMI)...
- Herpes zoster: Burden of disease in FranceS Gonzalez Chiappe
INSERM, U707, F 75012 Paris, France
Vaccine 28:7933-8. 2010..b>Herpes zoster data was obtained from the Sentinelles surveillance general practitioners (GPs) network, the PMSI Data ..
- Incidence, risk factors, and outcome of Herpes zoster in systemic lupus erythematosusEduardo F Borba
Rheumatology Division, Sao Paulo University, Sao Paulo, SP, Brazil
J Clin Rheumatol 16:119-22. 2010The incidence and outcome of Herpes zoster (HZ) in systemic lupus erythematosus (SLE) are not completely defined as well as the relevance to HZ of disease and therapy factors.
- Herpes zoster: risk categories for persistent painR J Whitley
Department of Pediatrics, University of Alabama at Birmingham, USA
J Infect Dis 179:9-15. 1999Acute neuritis and persistent pain are the most significant clinical manifestations of herpes zoster and are end points for clinical trials therapy...
- Risk of herpes zoster among patients with psychiatric diseases: a population-based studyY W Yang
Department of Dermatology, Taipei Medical University Hospital, Taipei, Taiwan
J Eur Acad Dermatol Venereol 25:447-53. 2011Psychiatric disorders have been shown to be associated with impaired immune response, including decreased cellular immunity to varicella-zoster virus. However, the risk of herpes zoster (HZ) in psychiatric patients is, to date, unknown.
- Assessing the potential effects and cost-effectiveness of programmatic herpes zoster vaccination of elderly in the NetherlandsAlies van Lier
Department of Epidemiology and Surveillance, Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
BMC Health Serv Res 10:237. 2010b>Herpes zoster (HZ) is a painful disease affecting a considerable part of the elderly. Programmatic HZ vaccination of elderly people may considerably reduce HZ morbidity and its related costs, but the extent of these effects is unknown...
- Epidemiology and economic burden of herpes zoster and post-herpetic neuralgia in Italy: a retrospective, population-based studyLeonardo Emberti Gialloreti
Dipartimento di Sanita Pubblica, Universita di Roma Tor Vergata, Via Montpellier 1, 00133 Roma, Italy
BMC Infect Dis 10:230. 2010Data on the epidemiology and cost of herpes zoster (HZ) and post-herpetic neuralgia (PHN) in Italy are limited...
- Acute pain in herpes zoster and its impact on health-related quality of lifeJennifer Katz
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
Clin Infect Dis 39:342-8. 2004..on physical and emotional functioning have been examined in a number of studies, the impact of acute pain in herpes zoster ("shingles") on health-related quality of life has been neglected...
- What does epidemiology tell us about risk factors for herpes zoster?Sara L Thomas
Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
Lancet Infect Dis 4:26-33. 2004Reactivation of latent varicella zoster virus as herpes zoster is thought to result from waning of specific cell-mediated immunity, but little is known about its determinants in individuals with no underlying immunosuppression...
- Pain, medication use, and health-related quality of life in older persons with postherpetic neuralgia: results from a population-based surveyGerry Oster
Policy Analysis Inc, Brookline, Massachusetts 02445, USA
J Pain 6:356-63. 2005..61; respondents rated their overall health as 65.7 (+/-21.1) on a 100-point scale. PHN causes substantial pain, dysfunction, and poor health-related quality of life in older persons, many of whom might be suboptimally treated...
- The incidence of herpes zoster in a United States administrative databaseRalph P Insinga
Department of Health Economic Statistics, Merck Research Laboratories, Blue Bell, PA, USA
J Gen Intern Med 20:748-53. 2005Few recent studies have reported data on the incidence of herpes zoster (HZ) in U.S. general clinical practice.
- Estimating the cost-effectiveness of vaccination against herpes zoster in England and WalesA J van Hoek
Modelling and Economics Unit, Health Protection Agency, Centre for Infections, London NW9 5EQ, UK
Vaccine 27:1454-67. 2009A live-attenuated vaccine against herpes zoster (HZ) has been approved for use, on the basis of a large-scale clinical trial that suggests that the vaccine is safe and efficacious...
- Predicting postherpetic neuralgia in elderly primary care patients with herpes zoster: prospective prognostic studyWim Opstelten
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, P O Box 85060, 3500 AB Utrecht, The Netherlands
Pain 132:S52-9. 2007Postherpetic neuralgia (PHN) is the most frequent complication of herpes zoster (HZ) and difficult to treat. Timely identification of high-risk HZ-patients enables physicians to focus on PHN prevention...
- Determinants of non-compliance with herpes zoster vaccination in the community-dwelling elderlyWim Opstelten
University Medical Center Utrecht, Julius Center for Health Sciences and Primary Care, Utrecht, The Netherlands
Vaccine 27:192-6. 2009..studies on vaccine acceptance, we assessed determinants of compliance of the community-dwelling elderly with herpes zoster (HZ) vaccination in an existing influenza vaccination program...
- Exposure to varicella boosts immunity to herpes-zoster: implications for mass vaccination against chickenpoxM Brisson
Immunisation Division, PHLS Communicable Disease Surveillance Centre, London, UK
Vaccine 20:2500-7. 2002..Mass varicella vaccination is expected to cause a major epidemic of herpes-zoster, affecting more than 50% of those aged 10-44 years at the introduction of vaccination...
- Pain following herpes zoster: the influence of changing population characteristics and medical developmentsRobert W Johnson
Pain 128:3-5. 2007
- [Laboratory diagnosis of herpes zoster: virology or serology?]Andreas Sauerbrei
Institut für Antivirale Chemotherapie, Friedrich Schiller Universitat Jena
Med Klin (Munich) 97:123-7. 2002The diagnosis of herpes zoster is mostly based on clinical findings. In atypical cases, rapid and reliable virological diagnostics is necessary because effective antiviral chemotherapy is available.
- Serological detection of varicella-zoster virus-specific immunoglobulin G by an enzyme-linked immunosorbent assay using glycoprotein antigenA Sauerbrei
Institute of Virology and Antiviral Therapy, University Clinic of Jena, Postfach, Hans Knoell Strasse 2, D 07745 Jena, Germany
J Clin Microbiol 44:3094-7. 2006..The test can also be recommended for measuring antibody response after varicella vaccination, particularly after the cutoff value was optimized...
- Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP)Mona Marin
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, CDC, Atlanta, GA 30333, USA
MMWR Recomm Rep 56:1-40. 2007..ACIP also approved criteria for evidence of immunity to varicella...
- Herpes zosterDavid W Wareham
Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and The London, Queen Mary's School of Medicine and Dentistry
BMJ 334:1211-5. 2007
- Occipital neuralgia evoked by facial herpes zoster infectionTakeshi Kihara
Department of Neuroscience for Drug Discovery, Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida-Shimoadachi-Cho 46-29, Sakyo-ku, Kyoto 606-8501, Japan
Headache 46:1590-1. 2006..This was diagnosed as herpes zoster. This case represents a combination of facial herpes lesions and pain in the C2 and C3 regions...
- Cost-effectiveness of herpes zoster vaccine: flawed assumptions regarding efficacy against postherpetic neuralgiaMarc Brisson
Clin Infect Dis 45:1527-9. 2007
- Clinical relevance of quantitative varicella-zoster virus (VZV) DNA detection in plasma after stem cell transplantationJ S Kalpoe
Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
Bone Marrow Transplant 38:41-6. 2006..VZV-DNA detection in plasma of allo-SCT recipients appears clinically relevant as this may support early recognition and therapeutic management of VZV-infections following allo-SCT...
- Primary varicella and herpes zoster among HIV-infected children from 1989 to 2006Sarah M Wood
Special Immunology Service, Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Pediatrics 121:e150-6. 2008The primary objective of this study was to determine the incidence of herpes zoster in perinatally HIV-infected children...
- The safety profile of varicella vaccine: a 10-year reviewSusan A Galea
Merck Research Laboratories, Clinical Risk Management and Safety Surveillance, North Wales, Pennsylvania 19454 1099, USA
J Infect Dis 197:S165-9. 2008..Among 697 herpes zoster reports, PCR analysis identified Oka VZV in 57 reports and wild-type VZV in 38 reports...
- Transmission of a newly characterized strain of varicella-zoster virus from a patient with herpes zoster in a long-term-care facility, West Virginia, 2004Adriana S Lopez
National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Infect Dis 197:646-53. 2008We investigated a small outbreak of varicella in a long-term-care facility after a case of herpes zoster. Clinical specimens and environmental samples were collected from all case patients and from surfaces in the case patients' rooms ..
- Double-blind study comparing 2 dosages of valacyclovir hydrochloride for the treatment of uncomplicated herpes zoster in immunocompromised patients 18 years of age and olderAnita Arora
Department of Dermatology, University of Texas Houston School of Medicine, Houston, TX 77030, USA
J Infect Dis 197:1289-95. 2008..assess the safety and efficacy of an oral dosage of valacyclovir, 1 g TID versus 2 g TID, for the treatment of herpes zoster in immunocompromised patients > or =18 years of age...
- [Antiviral resistance of herpes simplex virus and varicella-zoster virus]Tohru Daikoku
Department of Virology, University of Toyama
Nippon Rinsho 65:480-6. 2007
- Herpes zoster: new insights provide an important wake-up call for management of nosocomial transmissionJudith Breuer
J Infect Dis 197:635-7. 2008
- Triad of severe abdominal pain, inappropriate antidiuretic hormone secretion, and disseminated varicella-zoster virus infection preceding cutaneous manifestations after hematopoietic stem cell transplantation: utility of PCR for early recognition and therRachel Rau
Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 1104, USA
Pediatr Infect Dis J 27:265-8. 2008..She was treated with acyclovir and subsequently developed VZV antigen-positive zoster. Detection of VZV DNA in blood may be useful for early diagnosis in immunocompromised hosts who present with zoster without skin lesions...
- [Acute retinal necrosis--today, past and future]Hiroshi Goto
Nippon Ganka Gakkai Zasshi 112:105-6. 2008
- The impact of the varicella vaccination program on herpes zoster epidemiology in the United States: a reviewMeredith A Reynolds
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
J Infect Dis 197:S224-7. 2008Speculation that a universal varicella vaccination program might lead to an increase in herpes zoster (HZ) incidence has been supported by modeling studies that assume that exposure to varicella boosts immunity and protects against ..
- Two cases of varicella zoster virus meningitis found in pediatric patients after bone marrow transplantation despite valaciclovir prophylaxis and without skin lesionsNicolas Leveque
Laboratoire de Virologie, Hopital E Herriot, Hospices Civils de Lyon, Lyon, France
J Med Virol 78:514-6. 2006..This recurrence occurred despite valaciclovir prophylaxis and without skin lesions. The two patients received aciclovir intravenously and immunoglobulins infusion. They responded to treatment and their clinical state improved rapidly...
- [Disseminated herpes zoster in diabetes mellitus]N Graue
, , Venerologie und Allergologie, Hufelandstrasse 55, 45147 Essen
Dtsch Med Wochenschr 131:384-6. 2006..DIAGNOSIS AND TREATMENT: After the clinical diagnosis of disseminated herpes zoster had been confirmed systemic therapy with aciclovir 10 mg/kg day was started...
- Varicella zoster virus: natural history and current therapies of varicella and herpes zosterJudy Breuer
Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts, UK
Herpes 14:25-9. 2007..Treatment is recommended for all individuals with herpes zoster, especially those aged over 50 years...
- [Swiss recommendations for the management of varicella-zoster virus infections]P Meylan
Institut de microbiologie et Division des maladies infectieuses, CHUV, Lausanne
Rev Med Suisse 3:2116-22, 2124-9. 2007..The aim is to improve the care of affected patients and to reduce complications...
- Quantification of circulating varicella-zoster virus DNA for follow-up in a case of visceral varicella-zoster infection ameliorated with intravenous acyclovirJo Ishizawa
Department of Hematology, Shizuoka Red Cross Hospital, Shizuoka, Japan
Int J Hematol 85:242-5. 2007..The viral DNA copy number in whole blood remained positive, however, but was reduced. Further treatment with intravenous ACV led to VZV DNA becoming undetectable in whole blood, a result not achieved with oral valacyclovir...
- Varicella zoster virus infection: clinical features, molecular pathogenesis of disease, and latencyNiklaus H Mueller
Department of Neurology, University of Colorado School of Medicine, 4200 East 9th Avenue, Mail Stop B182, Denver, CO 80262, USA
Neurol Clin 26:675-97, viii. 2008..This article discusses the clinical manifestations, treatment, and prevention of VZV infection and reactivation; pathogenesis of VZV infection; and current research focusing on VZV latency, reactivation, and animal models...
- Different genotype pattern of varicella-zoster virus obtained from patients with varicella and zoster in GermanyA Sauerbrei
Institute of Virology and Antiviral Therapy, Friedrich Schiller University of Jena, Jena, Germany
J Med Virol 79:1025-31. 2007..As reasons, the spread of viruses, which may be imported originally by persons immigrating from warmer climates, or the recombination between wild-and vaccine-type viruses have to be considered...
- Investigations of the pathogenesis of Varicella zoster virus infection in the SCIDhu mouse modelAnn M Arvin
Departments of Pediatrics, and Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
Herpes 13:75-80. 2006..human herpesvirus that causes varicella, establishes latency in sensory ganglia and may reactivate to cause herpes zoster in healthy and immunocompromised patients...
- Prevention of VZV infection in immunosuppressed patients using antiviral agentsMichael Boeckh
Fred Hutchinson Cancer Research Center, Program in Infectious Diseases, University of Washington, Seattle, WA 98109, USA
Herpes 13:60-5. 2006..Current evidence on the use of antiviral agents in the prevention of reactivation disease and management of exposure to VZV is discussed...
- Recommendations for the management of herpes zosterRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
Clin Infect Dis 44:S1-26. 2007The objective of this article is to provide evidence-based recommendations for the management of patients with herpes zoster (HZ) that take into account clinical efficacy, adverse effects, impact on quality of life, and costs of ..
- Perspective on live varicella vaccineAnne A Gershon
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
J Infect Dis 197:S242-5. 2008..vaccine with 10 times the titer was developed for immunization of healthy individuals >60 years of age against herpes zoster (HZ)...
- Postexposure prophylaxis against varicella zoster virus infection among hematopoietic stem cell transplant recipientsDavid M Weinstock
Biol Blood Marrow Transplant 12:1096-7. 2006
- Emerging therapies for herpes viral infections (types 1 - 8)Arun Chakrabarty
Solano Clinical Research, Davis, California, USA
Expert Opin Emerg Drugs 9:237-56. 2004..The new helicase primase inhibitors, which are the first non-nucleoside antiviral compounds, are being investigated for treatment of HSV disease, including infections resistant to existing therapy...
- The optimization and validation of the glycoprotein ELISA assay for quantitative varicella-zoster virus (VZV) antibody detectionOlivia Hammond
Vaccine and Biologics Research, Merck Research Laboratories, Wayne, Pennsylvania, USA
J Med Virol 78:1679-87. 2006..In this article, we describe the gpELISA method, detail the procedures used to evaluate assay performance, and present the operating characteristics of the second generation gpELISA...
- Varicella-zoster-virus genotypes in East London: a prospective study in patients with herpes zosterN Sengupta
Department of Virology, Centre for Infectious Diseases, Institute of Cell Molecular Sciences, Queen Mary School of Medicine and Dentistry, Barts, Whitechapel, London, E1 2AT, United Kingdom
J Infect Dis 196:1014-20. 2007A total of 298 patients with herpes zoster were recruited as part of 2 community-based studies in East London between 1998 and 2003...
- Herpes zoster in childhoodAlexander K C Leung
Department of Pediatrics, University of Calgary, Alberta, Canada
J Pediatr Health Care 20:300-3. 2006b>Herpes zoster is caused by reactivation of latent varicella-zoster virus that resides in a dorsal root ganglion. Herpes zoster can develop any time after a primary infection...
- Varicella-zoster virus encephalitis in a patient undergoing unrelated cord blood transplantation for myelodysplastic syndrome-overt leukemiaKenji Fukuno
Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Shirokanidae, Tokyo
Int J Hematol 84:79-82. 2006..MRI scans showed substantial resolution but with mild residual lesions. The present report indicates that VZV should be considered as a possible causative agent in patients who develop multifocal neurologic symptoms of the CNS after SCT...
- The effect of low-dose aciclovir on reactivation of varicella zoster virus after allogeneic haemopoietic stem cell transplantationK J Thomson
Department of Haematology, University College London Hospitals, 98 Chenies Mews, London WC1E 6HX, UK
Bone Marrow Transplant 35:1065-9. 2005....
- Varicella-zoster virus: atypical presentations and unusual complicationsJohn W Gnann
University of Alabama at Birmingham and Birmingham VA Medical Center, Birmingham, Alabama 35294-2170, USA
J Infect Dis 186:S91-8. 2002Varicella-zoster virus (VZV) is the etiologic agent of varicella (primary infection) and herpes zoster (reactivation of latent infection)...
- Detection and genotyping of varicella-zoster virus by TaqMan allelic discrimination real-time PCRPaul A Campsall
Department of Pathology and Laboratory Medicine, University of British Columbia and Children's and Women's Health Centre of British Columbia, Canada
J Clin Microbiol 42:1409-13. 2004..live attenuated Oka varicella-zoster virus (VZV) vaccine subsequently develop attenuated chicken pox and/or herpes zoster. To determine whether postvaccination varicella infections are caused by vaccine or wild-type virus, a simple ..
- Quantitative real time PCR detection of Varicella-zoster virus DNA in cerebrospinal fluid in patients with neurological diseaseStephan W Aberle
Institute of Virology, Medical University of Vienna, Kinderspitalgasse 15, 1095, Vienna, Austria
Med Microbiol Immunol 194:7-12. 2005..14). High copy numbers of VZV DNA in CSF were clearly associated with the severity of neurological disease and none of the patients with a VZV viral load below 10(4) copies had a disease course which required intensive care...
- Ten year follow-up of healthy children who received one or two injections of varicella vaccineBarbara Kuter
Merck Research Laboratories, PO Box 4, West Point, PA 19486, USA
Pediatr Infect Dis J 23:132-7. 2004..a two dose regimen of varicella virus vaccine live Oka/Merck (VARIVAX; Merck & Co., Inc., West Point, PA) in approximately 2000 children were compared during a 9- to 10-year follow-up period...
- Development of resistance to acyclovir during chronic infection with the Oka vaccine strain of varicella-zoster virus, in an immunosuppressed childMyron J Levin
Section of Pediatric Infectious Diseases, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
J Infect Dis 188:954-9. 2003..Three months later he developed herpes zoster, which developed into chronic verrucous lesions that were refractory to treatment with acyclovir and which ..
- [Does vaccination for chickenpox prevent herpes zoster? (interview by Waldtraut Paukstadt)]H W Doerr
MMW Fortschr Med 144:12. 2002
- VaricellaRobin English
Louisiana State University Health Sciences Center, New Orleans, LA, USA
Pediatr Rev 24:372-9. 2003
- Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosidesJ Balzarini
Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, Leuven, Belgium
Biochim Biophys Acta 1587:287-95. 2002..The bicyclic pyrimidine nucleoside analogues represent an entirely new class of highly specific anti-VZV compounds that should be further pursued for clinical development...
- Antiviral therapy for varicella and herpes zosterAnn M Arvin
Department of Pediatrics and Microbiology and Immunology, Stanford University School of Medicine, CA 94305, USA
Semin Pediatr Infect Dis 13:12-21. 2002Varicella-zoster virus (VZV) causes 2 clinical illnesses, varicella (chickenpox) and herpes zoster (shingles)...
- Disseminated varicella infection in adult renal allograft recipients: role of mycophenolate mofetilR Lauzurica
Nephrology Department, Kidney Transplant Unit, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
Transplant Proc 35:1758-9. 2003..Early treatment with high doses of acyclovir is fundamental in infection control. It is essential to perform a pretransplantation serological VZV study on all patients...
- VZV BACs: New Tools for Pathogenesis ResearchNikolaus Osterrieder; Fiscal Year: 2005Varicella zoster virus (VZV) causes chickenpox (varicella) and shingles (herpes zoster)...
- Cdk inhibitors: novel antivirals for VZVJennifer Moffat; Fiscal Year: 2007Immunocompromised individuals are at high risk for herpes zoster caused by reactivation of varicella zoster virus (VZV)...
- ANTIGENIC DETERMINANTS OF VARICELLA VIRUSCharles Grose; Fiscal Year: 2006Varicella-zoster virus (VZV) is the cause of chickenpox and herpes zoster. VZV infection is a recurrent problem in both transplant and cancer patients...
- STUDY & TREATMENT OF RETINOPATHY ASSOCIATED WITH AIDSWilliam Freeman; Fiscal Year: 1992..will include antiviral therapy with ganciclovir for that due to cytomegalovirus and with acyclovir for herpes zoster or varicella zoster retinitis. Newer drugs will be used as they are developed...
- Varicella zoster virus-Induced Pain in a Rat Model of Post-Herpetic NeuralgiaPaul R Kinchington; Fiscal Year: 2010Post-Herpetic Neuralgia (PHN) is a common and exceedingly painful complication of herpes zoster that is debilitating, intractable, long-lasting and difficult to treat...
- Varicella zoster virus-Induced Pain in a Rat Model of Post-Herpetic NeuralgiaPAUL KINCHINGTON; Fiscal Year: 2009Post-Herpetic Neuralgia (PHN) is a common and exceedingly painful complication of herpes zoster that is debilitating, intractable, long-lasting and difficult to treat...
- Impact of immune senescence on herpes zoster in a nonhuman primate modelIlhem Messaoudi; Fiscal Year: 2010Reactivation of latent varicella zoster virus (VZV) leads to herpes zoster (HZ, also known as shingles), a disease that causes major morbidity and occasionally mortality in older individuals. The incidence of HZ increases from 3...
- Novel Topical Treatment for Postherpetic NeuralgiaCharles Gauntt; Fiscal Year: 2005..PHN is defined as pain in the affected dermatome that persists or appears after the rash of herpes zoster (HZ) has healed...
- ANTIGENIC DETERMINANTS OF VARICELLA VIRUSCharles Grose; Fiscal Year: 1993..of both the common childhood illness chickenpox and, upon reactivation, the dermatomal exanthem shingles (herpes zoster)...
- BEHAVIORAL INTERVENTION FOR HERPES ZOSTER RISK IN AGINGMichael Irwin; Fiscal Year: 2003Description (adapted from investigator's abstract): The incidence and severity of herpes zoster (HZ) or shingles increase markedly with increasing age due to a decline in varicella zoster virus (VZV) specific immunity...
- Zeiss LSM 510-NLO multiphoton laser scanning microscopeJoseph Mazurkiewicz; Fiscal Year: 2003..cutaneous innervation in normal and pathologic skin to study pain and neural dysfunction resulting from Herpes Zoster using mutiply-fluorescent-labeled thick samples of human skin. Dr...
- DEPRESSION AND TRIAL OF VARICELLA VACCINE IN THE ELDERLYMichael Irwin; Fiscal Year: 2003..much evidence indicates that cell mediated immunity plays a critical role in limiting the occurrence of herpes zoster (HZ) and its complications, the effect of major depression on VZV-specific cellular immunity will be examined...
- PAIN & NEURAL DYSFUNCTION FROM ACUTE HERPES ZOSTERKarin Petersen; Fiscal Year: 2003Pain, nerve trunk inflammation, and neuronal injury are hallmarks of acute herpes zoster (AHZ or 'shingles')...
- PAIN & NEURAL DYSFUNCTION FROM ACUTE HERPES ZOSTERMichael Rowbotham; Fiscal Year: 2002Pain, nerve trunk inflammation, and neuronal injury are hallmarks of acute herpes zoster (AHZ or 'shingles')...
- ALTERED SENSIBILITY FOLLOWING PERIPHERAL NERVE DAMAGECLIFFORD WOOLF; Fiscal Year: 2007Peripheral nerve lesions (e.g. trauma, Herpes Zoster, diabetic and AIDs neuropathy) can lead to a loss of sensation as a result of the degeneration or death of primary sensory neurons in the dorsal root ganglion...