urination disorders

..Recent evidence of an association between LUTS/BPH and sexual dysfunction will be reviewed, as well as the effects of pharmacological treatment options for symptomatic LUTS/BPH on sexual function...

..Therefore, we have explored associations between Q (max) and voiding and storage sub-scores of the International Prostate Symptom Score (IPSS) before and after treatment with QoL...

..We investigated the relationship of ANS activity to LUTS as well as to objective measures of BPH in men with BPH...

..This article reviews findings from recent studies investigating urinary, sexual, and defecation dysfunction after rectal cancer surgery and discusses questions to be studied in the future...

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..Surgical treatment often involves a degree of bladder denervation to reduce bladder activity. This can consequently produce voiding difficulties which necessitate patients to self-catheterise on a longterm basis...

..The aim of the present study was to compare the effectiveness of a cholinergic drug, an alpha-blocker and combinations of the two for the treatment of underactive detrusor...

..To describe how different lower urinary tract symptoms (LUTS) affect the quality of life (QOL) in men...

..Somatosensory evoked potentials (SEPs) of the pudendal and posterior tibial nerves were evaluated in patients implanted with a monolateral permanent quadripolar electrode...

..The cardiovascular profile of silodosin suggests therefore that it is a safe and well-tolerated drug...

..To assess the hypothesis that as lower urinary tract symptoms (LUTS) increase in severity, the impact as measured by the BPH impact index (BII) would also increase...

..To evaluate the effect of once-daily, extended-release tolterodine on urinary urgency in patients with overactive bladder...

..Medical therapies, and particularly alpha(1)-adrenoceptor antagonists such as tamsulosin, can be considered a first-line treatment option for LUTS/BPH because they provide effective relief of bothersome LUTS with excellent tolerability...

..The association between the severity of LUTS and prostate volume, prostate-related variables and general life-style factors was investigated in a large number of patients with persistent LUTS suggestive of BPH (LUTS/BPH)...

..The presence of the metabolic syndrome might be a mediator of this association...

..The association between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS) is unclear. Conventionally, little attention has been given to the association between ED and LUTS...

..The objective of the study was to compare sacral nerve stimulation (SNS) to pudendal nerve stimulation (PNS) for voiding dysfunction...

..The aim of this study was to provide an objective evaluation of symptoms that precede a diagnosis of ovarian cancer...

..Considering the importance of bothersomeness associated with lower urinary tract symptoms for the therapy decision, the joint use of the IPSS and SPI seems appropriate...

..To assess if there is an underlying vascular association between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED)...

..We determined the effect of lower urinary tract symptoms (LUTS) on the incidence of erectile dysfunction (ED)...

..To describe an observational study to establish whether localized activity arises in the normal human bladder, and whether there is any correspondence between changes in such activity and reported sensation...

..To assess the effect of prolonged sacral neuromodulation testing using permanent leads comparing the usual evaluation period of 4 to 7 days to a prolonged evaluation period of a minimum of 14 days...

..To evaluate the clinical efficacy and tolerability of tolterodine extended-release (ER) in continent patients with overactive bladder (OAB) and nocturia...

..Recent data suggest an association between erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Anecdotally some patients cite improvement in LUTS while using sildenafil...

..It is unclear whether autonomic nerve preservation is suitable curative procedure. We clarify the significance of autonomic nerve preservation for an advanced lower rectal cancer...

..We evaluated sildenafil for erectile dysfunction and lower urinary tract symptoms in men with the 2 conditions...

..We present our long-term experience with sacral neuromodulation devices placed in patients with painful bladder syndrome to determine whether the benefit decreases over time...

..We investigated which factors are most bothersome to preoperative patients with benign prostatic hyperplasia (BPH)...

..The International Prostate Symptom Score and International Index of Erectile Function questionnaires were useful in assessing urinary and sexual function...

..It also signifies a more severe degree of obstruction in male patients with lower urinary tract symptoms and bladder outlet obstruction due to benign prostatic hyperplasia...

..The aim of this review is to present up-to-date data and controversies associated with non-neurogenic female voiding dysfunction...

..We determined the clinical efficacy and safety of terazosin in the treatment of patients with female lower urinary tract symptoms...

..Symptoms of ovarian cancer are often vague and consequently a high proportion of women with ovarian cancer are not referred to the appropriate clinic...

..Hysterectomy may affect bladder and bowel function. A retrospective study was performed to compare the prevalence of micturition and defecation symptoms between different modes of hysterectomy...

..To prospectively evaluate the effectiveness of tamsulosin in treating women with voiding difficulty...

..To assess the (i) the overlap between voiding, storage, and postmicturition symptoms; and (ii) the relative effect of bother and implications for treatment seeking within these symptom groups, using data from the EpiLUTS study...

..Likewise, understanding that the impact of LUTS on HRQL and the degree of bother, rather than the frequency of LUTS, are significant drivers for treatment seeking might aid in assisting patients to make decisions about treatment...

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..Minneapolis, MI, USA) device for sacral nerve stimulation (SNS)...

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..We attempted to determine whether tamsulosin is an efficacious therapy for the treatment of lower urinary tract symptoms (LUTS) in women...

..The objective of this study was to examine the associations between psychological stress reactivity and BPH disease parameters...

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..These findings confirm that LUTS and EP are prevalent in the US population, affecting both patient and spouse, and may help in developing management strategies for EP...

..Studies treating one condition (e.g. ED) and measuring the impact on the other (e.g. LUTS) should further contribute to support this common link...

..1%) had a positive urinary culture after the investigation but was asymptomatic. Seventeen women reported mild to moderate de novo dysuria. CONCLUSIONS: Urinary symptoms and morbidity after ambulatory monitoring is low...

..We evaluated to what extent lateral lymph node dissection (LND) interferes with bladder and male sexual functions after radical rectal excision with adoption of careful total autonomic nerve preservation...

..To evaluate the efficacy and safety of nighttime dosing with tolterodine extended release (TER) in men with overactive bladder (OAB) and nocturia...

To probe the therapeutic effect and safety of ginger-salt-partitioned moxibustion on urination disorders poststroke.

..e. urgency, incontinence, and frequency, with additional objectives being to assess the safety and tolerability of solifenacin and to compare the efficacy and safety of solifenacin with tolterodine 2 mg twice daily...

..The distribution of IPSS-QI was very similar within each category of the IPSS severity in both sexes, showing that LUTS was equally bothersome to both sexes. These data should be taken into account to evaluate LUTS in both sexes...

..We evaluated the safety and efficacy of 80 W potassium-titanyl-phosphate (KTP) laser vaporization of the prostate in men with prostate volumes >70 ml...

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..To assess the impact of lower urinary tract symptoms (LUTS) on general quality-of-life (QOL) measures in an outpatient setting...

..The results show that naftpidil is effective for LUTS caused by BPH, and that improvement of nocturia and incomplete emptying contributed to the improvement in QOL...

..Urodynamics is an objective method of diagnosing bladder outlet obstruction (BOO) in men. This study examined the immediate and 6-mo reproducibility of this investigation...

..It was concluded that Goshajinkigan was effective for pollakisuria with prostatic disease, and the administration of the agent for 8 weeks or longer was needed to improve lower urinary tract symptoms...

..CONCLUSION: Results suggest that these treatments, used in combination, may reduce urinary symptoms in MS. Further research will establish the effectiveness of these interventions...

..The aim of the present paper is to elucidate the possible involvement of time-dependent parameters as obtained by uroflowmetry in the manifestation of lower urinary tract symptoms (LUTS) in elderly patients...

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..Despite this, large-scale trials to test the efficacy of such combination therapy are still lacking...

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..Overall, sensory urgency and detrusor overactivity appear to be part of the same spectrum of bladder dysfunction...

..To report results from a 2-year longitudinal survey of lower urinary tract function and quality of life (QOL) in men after radical retropubic prostatectomy (RP) for localized prostate cancer...

..Our results suggest that both subjective and objective numbers of nocturia episodes are associated with improvements in subjective and objective nocturnal frequencies, respectively...

..Lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) are common problems in middle-aged and older men. Recently, epidemiologic studies have shown significant associations between severity of LUTS and male sexual dysfunction...

..To investigate the associations of symptoms and the quality of life (QOL) with objective variables in a strictly selected large cohort of subjects with symptomatic benign prostatic obstruction (BPO)...

..To evaluate the therapeutic effect of harnal and proscar in treating benign prostatic hyperplasia (BPH)...

..In particular those patients with the stigmatizing symptoms urinary urgency and frequency benefit from such treatment...

..In contrast to weak urinary stream and hesitancy, the bothersomeness of incomplete emptying and frequency was strongly associated with well-being...

..To determine whether digital rectal examination (DRE) would affect uroflowmetry parameters and whether these findings were not due to the circaidan changes...

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..This is in contrast to diminishing PFRs seen in normal men as they age. Our study suggests that age-related reduction in PFR and voided volumes is largely eliminated after total removal of the prostate gland...

..Although we cannot estimate patients' satisfaction by the observed changes in scores, the rates of improvement were lowest for nocturia among the seven symptoms of IPSS after conservative and invasive treatments for BPH...

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..It is safe, effective, and well-tolerated. Furthermore, it is not related to the patient's willingness to complete treatment...

..Nocturnal polyuria is a frequent problem. However, simple hygiene and dietary measures and the control of certain concomitant diseases can usually relieve the symptoms. Medical treatment relies on desmopressine...

..94 years) and 64.62 years (SD=7.94 years) respectively. CONCLUSIONS: The result showed that operative procedure had significantly improved the overall health-related quality of life of LUTS patients compared to those on medical treatment...

..This is a concise and timely update of the most recent developments in the clinical research on the investigation of benign prostatic hyperplasia...

..To gain insight from an adaptable computer model of micturition into the pathophysiological phenomena occurring during voiding in men with lower urinary tract symptoms due to benign prostatic enlargement (BPE)...

..Information obtained by asking prostate-specific symptom questions cannot, however, serve as the foundation for the GP to find those men whose problems would be solved by actions directed at the prostate...

..The AUA symptom score has the potential to identify these men and its validity in black Americans has now been established...

..CONCLUSIONS: Long-term treatment with tamsulosin is safe and well tolerated in patients with lower urinary tract symptoms/benign prostatic hyperplasia. Improved efficacy was sustained during 4 years of followup...

..CONCLUSION: Uroflowmetry and IPSS, although not allowing a definitive diagnosis of obstruction, may nonetheless satisfy the clinical need of a rapid, easy and accurate tool for the noninvasive screening of LUTS patients...

..To investigate the effect of position on voiding using uroflowmetry and post-void residual (PVR) urine volume assessment in patients with lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH)...

..Its effectiveness was similar to that of other alpha-antagonists, increasing slightly at higher doses. Adverse effects were generally mild but the incidence, including treatment withdrawals, increased substantially at higher doses...

..It is well tolerated from a cardiovascular viewpoint and is not associated with abnormal ejaculation...

..Traditional surgical techniques such as transurethral resection of the prostate are still appropriate for some men, although with improved medical treatments available the number of men undergoing surgery is declining...

..However, 17% of the patients with efficacy graded as "fair" by Level I criteria might be judged "unchanged" from the viewpoint of urologists...

..We examined the influence of aging on bladder function in men and women...

..BOO has no significant influence on residual urine. Some patients with normal or weakened detrusor contractility may have more residual urine...

..The velocity-flow parameters changed after alpha 1-blocker treatment. We confirmed that the transperineal ultrasound urodynamic study is not only noninvasive but also informative...

..This method can serve to assess the quality of surgical treatment for rectal cancer. A standardized definition of relevant urinary bladder malfunctions is required...

..We provide an overview of the medical literature supporting the combined use of muscarinic and alpha-adrenergic antagonist therapy for the treatment of voiding dysfunction...

..Maximum amplitude of the involuntary contractions was significantly reduced and in 33% patients the involuntary contractions disappeared. Further studies with different concentrations are recommended...

..Using this model allows one to explore the limits of understanding prostatic neuroregulation, to explore neurotrophic influences on exocrine gland development, and to possibly uncover novel methods to influence prostate disease. ..

..Results of this research will aid in the understanding of how diabetic neuropathy contributes to sexual dysfunction and elucidate possible mechanisms to prevent them. ..

..We are proposing a 3-arm, placebo/sham controlled, randomized clinical trial using changes in symptoms as the primary ..

..Secondary Aim: Unique to this submission is whether a chief complaint analysis, sleep scale measures or direct/indirect healthcare costs analysis provides reliable or useful information. ..

..The MIST Study Group will be a blueprint for a technology assessment group applicable to other areas of urology and other medical or surgical subspecialties. ..

..8) Determine whether saw palmetto or pygeum africanum compared to placebo induce measurable changes in prostate volume, transition zone volume, serum PSA and other serum or tissue based biomarkers of BPH. ..

..Baseline urodynamic parameters which may predict improved outcome after MIST 3. The success of various types of MIST in treating BPH in African - American, Hispanic and Caucasian men. ..

..forms of BPH resulting in different rates of progression and differential response to therapy? and, D) whether concomitant prostate conditions such as prostatitis are effected by phytotherapeutic intervention for BPH? ..

..b. To model urinary storage in health and disease c. To model urinary emptying in health and diseas ..

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..vaginal) is best suited for an individual woman. This trial is a feasible, scientifically relevant randomized surgical trial. The draft protocol is suitable for PFDN Steering Committee discussion and revision, prior to implementation. ..

..Key personnel for the project are Raymond C. Rosen, Ph.D., Professor of Psychiatry and Medicine at UMDNJ, who will serve as PI, and Joseph Catania, PhD, co-PI, from the AIDS Research Institute at UCSF. ..

..Finally, salary support will allow me to continue and expand my mentoring efforts for the benefit of current and future colleagues, fellows and residents. ..

..iii) Finally, the proposed sub-study will investigate the relationship between changes in sexual function and quality of life outcomes. ..

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..Additionally, the proposed study will provide data on the relationship between sexual function outcomes and other key measures of mood state and quality of life in the main Look AHEAD trial. ..

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..As there are no existing studies of longitudinal assessments of both erectile dysfunction and endothelial dysfunction, the proposed study is likely to provide new information in this area. ..

..We believe that we can continue to be a productive member of the UITN, with the ultimate objective of improving quality of life for adults through the conduct of high impact clinical research in urinary incontinence. ..

..The long-term goal of this proposal is to expand the findings of this project into an R01 application in order to translate our findings into relevant clinical studies. ..

..Adverse events and complications will be monitored. Ancillary studies as agreed upon by the ICCRN will be carried out in conjunction with the clinical trial. ..

..Based on our previous research and that of others, we believe this study is a critical next step to improve the management of a prevalent and morbid condition that profoundly affects the quality of life of this population. ..

..Dr. Xiao, in China, developed a new procedure to rewire the nerves affecting the bladder, and this project aims to scientifically establish the safety and effectiveness of the surgical procedure. ..

..Therefore, this study will yield important information related to optimizing treatment of OAB in men. ..

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..The outcomes of each specific aim will be carefully tracked and evaluated utilizing a number of quantitative measures. ..

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..Insight into these cellular processes could be exploited to develop afferent based treatments for OAB employing pharmacologic, molecular or gene based strategies. ..

..We hope that by identifying factors affecting genitourinary conditions we can help in the development of primary and secondary prevention interventions. ..

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..In so doing, our findings will facilitate appropriately individualizing decision making based on unique characteristics of each prostate cancer patient and his partner. ..

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..This type of information will allow physicians to more effectively counsel and treat their incontinent female patients to further enhance long-term quality of life. ..

..The outcome of these studies will help guide the development of effective immunization strategies targeting hormone-responsive TAA in human prostate and other cancers. ..

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..Work of this nature may decrease the morbidity and mortality that is caused by bladder outlet obstruction. ..

..She is a mentor to young clinical investigators and is the research director of the newly initiated Fellowship in Female Pelvic Medicine and Reconstructive Surgery at UAB ..

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..The findings from this prospective, observational study will provide benchmarks to guide outcomes expectations and to facilitate evidence-based decisions regarding therapy. ..

..Bradley's research career development. Dr. Bradley has the enthusiastic support of the Colleges of Medicine and Public Health, the Department of Obstetrics and Gynecologv and her mentors and collaborators. ..

..On a theoretical level, the integration of findings will advance self-regulation theory and inform decision making and health behavior choice in general. ..

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..On a theoretical level, the integration of findings will advance self-regulation theory and inform decision making and health behavior choice in general. ..

..g., misconception about the disease) and emotional factors (e.g., cancer worry) that might interfere with decision making. The efficacy and feasibility of the proposed intervention will be assessed in a randomized controlled trial. ..

..It is expected that PIES will result in an increase in disease and treatment knowledge, high satisfaction ratings with the information provided, and that PIES will facilitate treatment decision making. ..