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| kidney failureSummarySummary: A severe irreversible decline in the ability of kidneys to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal failure, either acute (KIDNEY FAILURE, ACUTE) or chronic (KIDNEY FAILURE, CHRONIC), requires HEMODIALYSIS. Top Publications
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Publications
Mutation of BSND causes Bartter syndrome with sensorineural deafness and kidney failureR Birkenhäger
University Children s Hospital, Freiburg University, D 79106 Freiburg, Germany
Nat Genet 29:310-4. 2001..The gene encodes a hitherto unknown protein with two putative transmembrane alpha-helices and thus might function as a regulator for ion-transport proteins involved in aBS, or else as a new transporter or channel itself...
Mechanisms of Disease: erythropoietin resistance in patients with both heart and kidney failureKarien van der Putten
Department of Internal Medicine, Meander Medical Center, Amersfoort, The Netherlands
Nat Clin Pract Nephrol 4:47-57. 2008..Furthermore, neocytolysis could have a role. As resistance to exogenous EPO is associated with an increased risk of death, it is important to understand how cardiorenal failure affects EPO production and function...
Cardio-ankle vascular index and ankle pulse wave velocity as a marker of arterial fibrosis in kidney failure treated by hemodialysisAtsuhiro Ichihara
Internal Medicine, Keio University School of Medicine, Tokyo, Japan
Am J Kidney Dis 52:947-55. 2008Patients with kidney failure treated with hemodialysis have a high incidence of cardiovascular diseases caused by accelerated arteriosclerosis. However, accurate evaluation of the extent of arteriosclerosis is difficult...
Notch inhibition reverses kidney failureMatthias Kretzler
Nat Med 14:246-7. 2008
Kidney failure following liver resectionF Saner
Universitatsklinikum Essen, Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Essen, Germany
Transplant Proc 40:1221-4. 2008..Acute kidney failure correlates well with mortality...
Shiga toxin-producing Escherichia coli-associated kidney failure in a 40-year-old patient and late diagnosis by novel bacteriologic and toxin detection methodsLouise D Teel
Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
J Clin Microbiol 41:3438-40. 2003Infection with Shiga toxin-producing Escherichia coli (STEC) is the most common cause of kidney failure in children. High morbidity is also associated with infections in the elderly...
Therapy of anemia in kidney failure, using plasmid encoding erythropoietinPeggy Richard-Fiardo
INSERM, U533, Nantes F 44035, France
Hum Gene Ther 19:331-42. 2008....
Octreotide therapy for recurrent refractory hypoglycemia due to sulfonylurea in diabetes-related kidney failureRita R Gonzalez
New York University School of Medicine, New York 10016, USA
Endocr Pract 13:417-23. 2007....
[Gadolinium-induced systemic fibrosis in advanced kidney failure]A Rodriguez Jornet
Servicio de Nefrologia, Corporación Sanitaria Parc Taulí, Sabadell
Nefrologia 29:358-63. 2009..The patient had repeated exposure to gadodiamide; it increases the possibility of the systemic fibrosis. We review the recent literature of the nephrogenic systemic fibrosis...
Serum cystatin C as a new marker for noninvasive estimation of glomerular filtration rate and as a marker for early renal impairmentE Coll
Services of Nephrology, Biochemistry, Statistics, and Nuclear Medicine, Institut d Investigacions Biomediques August Pi i Sunyer, Hospital Clinic, University of Barcelona, Spain
Am J Kidney Dis 36:29-34. 2000....
Renal insufficiency and subsequent death resulting from cardiovascular disease in the United StatesPaul Muntner
Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana 70112, USA
J Am Soc Nephrol 13:745-53. 2002..This study indicates that, in a representative sample of the United States general population, renal insufficiency is independently associated with increased cardiovascular disease-related and all-cause mortality rates...
De novo Uroplakin IIIa heterozygous mutations cause human renal adysplasia leading to severe kidney failureDagan Jenkins
Nephro Urology Unit, Institute of Child Health, University College London, 30 Guilford Street, London WC1E 1EH, UK
J Am Soc Nephrol 16:2141-9. 2005..De novo heterozygous mutations in Uroplakin IIIa (UPIIIa) are reported in four of 17 children with kidney failure caused by renal adysplasia in the absence of an overt urinary tract obstruction...
The effect of renal insufficiency on workforce participation in the United States: an analysis using National Health and Nutrition Examination Survey III dataScott Klarenbach
Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
Am J Kidney Dis 40:1132-7. 2002..End-stage renal disease is associated with workforce nonparticipation, but no previous study has assessed the impact of renal insufficiency on employment status from a population standpoint...
Association of polymorphisms in monocyte chemoattractant protein-1 promoter with diabetic kidney failure in Korean patients with type 2 diabetes mellitusJu Young Moon
Department of Nephrology, College of Medicine, Kyunghee University, Seoul, Korea
J Korean Med Sci 22:810-4. 2007..We investigated the association of the -2518 A/G polymorphism in the MCP-1 gene with progressive kidney failure in Korean patients with type 2 diabetes mellitus (DM)...
Enoxaparin vs. unfractionated heparin for anticoagulation during continuous veno-venous hemofiltration: a randomized controlled crossover studyMichael Joannidis
Medical University Innsbruck, Division of General Internal Medicine, Department of Internal Medicine, Medical Intensive Care Unit, Anichstrasse 35, 6020 Innsbruck, Austria
Intensive Care Med 33:1571-9. 2007..The purpose of this study was to evaluate the efficacy and safety of the low molecular weight heparin enoxaparin as anticoagulant in continuous veno-venous hemofiltration (CVVH) compared with unfractionated heparin...
Carboplatin-based chemotherapy in patients with gynecological malignancies on long-term hemodialysisHitoshi Niikura
Department of Obstetrics and Gynecology, Tohoku University School of Medicine, Sendai, Japan
Anticancer Drugs 14:735-8. 2003..Our findings suggest these regimens are feasible, and the combination of paclitaxel and carboplatin is effective chemotherapy when administered to long-term hemodialysis patients with recurrent endometrial carcinoma...
Renal insufficiency in long-term lithium treatmentElie Lepkifker
Lithium Clinic, Psychiatric Division, Chaim Sheba Medical Center, Tel Hashomer, Israel
J Clin Psychiatry 65:850-6. 2004..However, about 20% of long-term lithium patients exhibited "creeping creatinine" and developed renal insufficiency...
CD151, the first member of the tetraspanin (TM4) superfamily detected on erythrocytes, is essential for the correct assembly of human basement membranes in kidney and skinVanja Karamatic Crew
Bristol Institute for Transfusion Sciences, Southmead Road, Bristol, BS10 5ND, United Kingdom
Blood 104:2217-23. 2004....
Prospective randomized trial to assess caloric and protein needs of critically Ill, anuric, ventilated patients requiring continuous renal replacement therapyC D Scheinkestel
Department of Intensive Care, Alfred Hospital, Melbourne, Australia, Australia
Nutrition 19:909-16. 2003..We also determined whether these feeding regimes affected patient outcome...
Acute cardio-renal syndrome: progression from congestive heart failure to congestive kidney failureDetlef Wencker
Department of Medicine, Section of Cardiovascular Disease, Yale University School of Medicine, 135 College Street, Suite 301, New Haven, CT 06510, USA
Curr Heart Fail Rep 4:134-8. 2007....
Diclofenac residues as the cause of vulture population decline in PakistanJ Lindsay Oaks
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164 7040, USA
Nature 427:630-3. 2004..We propose that residues of veterinary diclofenac are responsible for the OWBV decline...
[The start of renal replacement therapy in a Spanish department]I Castellano
Servicio de Nefrologia, Hospital San Pedro de Alcantara, Caceres
Nefrologia 26:445-51. 2006..The aim of our study was to analyse patient clinical and analytic characteristics at the time of initiating dialysis and to evaluate if morbimortality was affected by planned start...
Impact of renal insufficiency on short- and long-term outcomes after cardiac surgeryCharmaine E Lok
Institute for Clinical Evaluative Sciences and the University of Toronto, Toronto, Ontario, Canada
Am Heart J 148:430-8. 2004..This population-based study aimed to determine the risk of nondialysis dependent renal insufficiency (RI) on the long-term outcomes of patients who undergo CABG...
Cystatin C and beta2-microglobulin: markers of glomerular filtration in critically ill childrenJosé David Herrero-Morín
Hospital Universitario Central de Asturias, University of Oviedo, Julian Claveria Street, 33006, Oviedo, Spain
Crit Care 11:R59. 2007..The aim of the present study was to analyse the utility of serum cystatin C and beta2-microglobulin (B2M) in detecting decreased glomerular filtration rate in critically ill children...
Improvement of kidney failure with fetal kidney precursor cell transplantationSang Soo Kim
Department of Bioengineering, Hanyang University, Seoul, Korea
Transplantation 83:1249-58. 2007..Here, we show that the transplantation of fetal kidney precursor cells reconstitutes kidney tissues, reduces uremic symptoms, and provides life-saving metabolic support in kidney failure animal models.
Impact of increasing parenteral protein loads on amino acid levels and balance in critically ill anuric patients on continuous renal replacement therapyC D Scheinkestel
Alfred Hospital, Melbourne, Australia
Nutrition 19:733-40. 2003....
Elderly medical patients treated with prophylactic dosages of enoxaparin: influence of renal function on anti-Xa activity levelIsabelle Mahe
Internal Medicine Department A, Lariboisiere Hospital, Paris, France
Drugs Aging 24:63-71. 2007..The safety and optimal use of prophylactic treatment with low-molecular-weight heparins in elderly patients with impaired renal function remain undefined...
Renal impact of fluid management with colloids: a comparative reviewI J Davidson
The University of Texas Southwestern Medical Center at Dallas, Division of Surgical Transplantation, Dallas, Texas 75390, USA
Eur J Anaesthesiol 23:721-38. 2006..Colloids such as hydroxyethyl starch (HES), gelatin, dextran and albumin are useful for maintaining renal perfusion and function. The comparative renal effects of colloids have not been previously reviewed...
The impact of protein intake on renal function decline in women with normal renal function or mild renal insufficiencyEric L Knight
Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
Ann Intern Med 138:460-7. 2003..However, the long-term impact of protein intake on renal function in persons with normal renal function or mild renal insufficiency is unknown...
Kidney failure in mice lacking the tetraspanin CD151Norman Sachs
Division of Cell Biology, The Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands
J Cell Biol 175:33-9. 2006..Patients with a nonsense mutation in CD151 display end-stage kidney failure associated with regional skin blistering and sensorineural deafness, and mice lacking the integrin alpha3 ..
Evaluation of renal function in intensive care: plasma cystatin C vs. creatinine and derived glomerular filtration rate estimatesThierry Le Bricon
Laboratoire de Biochimie A, Hôpital St Louis AP HP, 1 avenue Claude Vellefaux, 75010 Paris, France
Clin Chem Lab Med 43:953-7. 2005..In intensive care unit surgical adult patients, CG CrCl provides an easy and cost-effective estimate of GFR. Superior to creatinine, plasma cystatin C can be measured in selected patients where CG CrCl is known to be inaccurate...
Peri-operative renal function and outcome after orthotopic heart transplantationJonah Odim
Department of Surgery, Medicine and Pathology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 1741, USA
J Heart Lung Transplant 25:162-6. 2006..Renal insufficiency is an established risk factor in patients undergoing cardiovascular surgery. We sought to evaluate the relationship between renal function and outcomes after orthotopic heart transplantation (OHT)...
Estimation of benchmark dose as the threshold levels of urinary cadmium, based on excretion of total protein, beta2-microglobulin, and N-acetyl-beta-D-glucosaminidase in cadmium nonpolluted regions in JapanEtsuko Kobayashi
Department of Occupational and Environmental Medicine A2, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuohku, Chiba, 260 8670 Japan
Environ Res 101:401-6. 2006....
Laparoscopic cyst decortication in autosomal dominant polycystic kidney disease: impact on pain, hypertension, and renal functionDavid I Lee
Department of Surgery, Division of Urologic Surgery, Washington University School of Medicine, St. Louis, Missouri, USA
J Endourol 17:345-54. 2003..Cyst decortication was not associated with worsening renal function; indeed, renal function remained largely unchanged over the 3-year follow-up period...
An analysis of the association between preoperative renal dysfunction and outcome in cardiac surgery: estimated creatinine clearance or plasma creatinine level as measures of renal functionFeng Wang
Department of Anesthesia, University of Ottawa Heart Institute, Ottawa, ON, Canada
Chest 124:1852-62. 2003..The routine preoperative estimation of ClCr may improve the identification of higher-risk cardiac surgical patients...
A study on the outcome of percutaneous transluminal renal angioplasty in patients with renal failureLouis Roussos
Department of Nephrology and Transplantation, Malmo University Hospital, Malmo, Sweden
Nephron Clin Pract 104:c132-42. 2006..The aim of this study was to evaluate the outcome of angioplasty and to identify risk factors associated with less successful outcomes in patients with atheromatous renal artery stenosis and renal failure of varying degrees...
Stable patients with atherosclerotic renal artery stenosis should be treated first with medical managementStephen C Textor
Division of Hypertension, Mayo Clinic, Rochester, MN, USA
Am J Kidney Dis 42:858-63. 2003
Predictors of outcome in Henoch-Schönlein nephritis in children and adultsRosanna Coppo
Nephrology, Dialysis and Transplantation Unit, Regina Margherita Hospital, Turin, Italy
Am J Kidney Dis 47:993-1003. 2006..Factors predictive of renal outcome were investigated in 219 cases of biopsy-proven Henoch-Schönlein purpura nephritis (HSPN); 83 children and 136 adults enrolled in a national study were followed up for up to 27 years (median, 4.5 years)...
Renal insufficiency as a predictor of adverse events and mortality after renal artery stent placementDavid J Kennedy
Department of Medicine, Medical College of Ohio, Toledo, OH 43614-2598, USA
Am J Kidney Dis 42:926-35. 2003..Importantly, improvement in renal function appears to be associated with increased survival...
Free serum concentrations of the protein-bound retention solute p-cresol predict mortality in hemodialysis patientsB Bammens
Department of Medicine, Division of Nephrology, University Hospital Gasthuisberg, Leuven, Belgium
Kidney Int 69:1081-7. 2006..These findings may encourage nephrologists to widen their field of interest beyond the scope of small water-soluble uremic solutes and middle molecules...
Factors influencing the progression of renal damage in patients with unilateral renal agenesis and remnant kidneyEster González
Department of Nephrology, Hospital Universitario 12 de Octubre, Madrid, Spain
Kidney Int 68:263-70. 2005....
Autologous stem cell transplantation in multiple myeloma: outcome in patients with renal failureLene M Knudsen
Department of Haematology, HS Rigshospitalet, Copenhagen, Denmark
Eur J Haematol 75:27-33. 2005..Whereas patients with moderate renal insufficiency seem to benefit from this treatment, patients in need for dialysis at the time of transplant must be carefully evaluated before proceeding to high-dose chemotherapy...
Antiretroviral drugs and the kidney: dosage adjustment and renal toleranceHassane Izzedine
Department of Nephrology, Pitie Salpetriere Hospital, Paris, France
Curr Pharm Des 10:4071-9. 2004..6 to 1%). Therefore, administration of antiretroviral drugs in human immunodeficiency virus (HIV) patients with nephropathy is not uncommon...
Clinical significance of renal function in hypertensive patients at high risk: results from the INSIGHT trialPeter W de Leeuw
Department of Medicine, University Hospital Maastricht, Maastricht, The Netherlands
Arch Intern Med 164:2459-64. 2004..To assess this role of renal function in more detail, we studied the evolution of renal function and the relationship of renal function with mortality and morbidity in the Intervention as a Goal in Hypertension Treatment (INSIGHT) study...
[Effect of inorganic nitrates on the morphofunctional condition of the kidney in the rat]Abdelwahab Zaki
Laboratoire de Physiologie Animale, Faculte des Sciences et Techniques, Beni Mellal, Maroc
Therapie 60:75-9. 2005..The aim of our experimental study was to determine the effect of exogenic nitrates on certain biological parameters in relation to renal insufficiency...
Administration of enoxaparin by continuous infusion in a naturalistic setting: analysis of renal function and safetyS L Kane-Gill
Cleveland Clinic Foundation, USA
J Clin Pharm Ther 30:207-13. 2005..To describe the clinical use and safety of continuous infusion (CI) enoxaparin in a naturalistic setting and to evaluate the influence of renal function on enoxaparin elimination...
Non-dialysis-dependent renal dysfunction and cardiac surgery-an assessment of perioperative risk factorsGopal C Kowdley
Department of Surgery, University of Chicago Hospitals, Chicago, Illinois, USA
Curr Surg 62:64-70. 2005..We set forth to ascertain preoperative risk factors important for predicting 2 endpoints: (1) dialysis at discharge and (2) hospital death...
Patients receiving maintenance hemodialysis with low vs high levels of nutritional risk have decreased morbidityJerrilynn D Burrowes
Department of Nutrition, C W Post Campus of Long Island University, Brooksville, NY 11548, USA
J Am Diet Assoc 105:563-72. 2005..To compare the demographic and clinical characteristics and outcomes (morbidity) of 442 patients receiving maintenance hemodialysis who are at different levels of nutritional risk...
[Drug dosage in renal failure -- traps and aids]Christian Aymanns
Nephrologie, , , Robert-Koch-Strasse 8, 89070 Ulm, Germany
Med Klin (Munich) 99:613-24; quiz 625. 2004
Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failureKazuo Mizutani
Terasaki Foundation Laboratory, Los Angeles, California, USA
Am J Transplant 5:2265-72. 2005..These antibodies found in the peripheral circulation, were not necessarily donor-specific, but their association with failure is consistent with a causality hypothesis...
The role of ultrasonography in the assessment of renal function in the elderlyNele Van den Noortgate
Department of Internal Medicine, Division of Geriatric Medicine, Ghent University Hospital, Ghent, Belgium
J Nephrol 16:658-62. 2003..This study evaluated a possible correlation between renal function and kidney size measured by ultrasonography (US), and whether the latter helps estimate GFR in the elderly...
Assessment of tumor-associated trypsin inhibitor (TATI) as a marker of renal functionGianfranco Tramonti
Department of Internal Medicine, Nephrology Unit, University of Pisa, Pisa, Italy
J Nephrol 16:663-72. 2003..200 d), as a glomerular filtration rate (GFR) marker. The results were compared with those of beta2-microglobulin and of creatinine (Cr)...
Preservation of renal function with surgical revascularization in patients with atherosclerotic renovascular diseaseLuke K Marone
Massachessetts General Hospital, Boston, Massachusetts 02111, USA
J Vasc Surg 39:322-9. 2004..These results may facilitate clinical decision making in the application of RAR for renal function salvage...
The CARI guidelines. Evaluation of renal functionDavid Johnson
Nephrology (Carlton) 10:S133-76. 2005
Restless Legs Syndrome in patients after renal transplantationMiklos Zsolt Molnar
Institute of Behavioral Sciences, Semmelweis University, Budapest, Hungary
Am J Kidney Dis 45:388-96. 2005..CONCLUSION: The prevalence of RLS is significantly lower in Tx patients than in patients on maintenance dialysis. Declining renal function is associated with increasing prevalence of the condition...
Renovascular injury: an argument for renal preservationKatherine A Barsness
Division of Pediatric Surgery, Department of Surgery, The Children s Hospital, University of Colorado Health Sciences Center, Denver, Colorado, USA
J Trauma 57:310-5. 2004..Renovascular injury is uncommon among children. This study hypothesized that preservation of the severely injured kidney can be achieved safely without renal insufficiency, postinjury hypertension, or the need for hemodialysis...
[No detectable nephrotoxic side effect using a dimer, non-ionic contrast media in cerebral perfusion computed tomography in case of suspected brain ischemia]M Petrik
Institut für Diagnostische Radiologie und Neuroradiologie, Greifswald
Rofo 177:1242-9. 2005..We were interested to find the best parameters for this examination...
Incidence and management of penetrating renal trauma in patients with multiorgan injury: extended experience at an inner city trauma centerBryan T Kansas
Department of Urology, Temple University School of Medicine, Philadelphia, Pennsylvania 19111, USA
J Urol 172:1355-60. 2004..With appropriate radiographic and/or surgical staging, it is possible to repair and salvage many of these kidneys despite extensive associated intraabdominal trauma...
Effect of off-pump and on-pump coronary artery bypass grafting on renal functionJale Bengi Celik
Department of Anesthesiology, Meram Medical School of Selcuk University, Konya, Turkey
Ren Fail 27:183-8. 2005..This study compared off-pump technique with on-pump technique on renal function in patients who underwent CABG...
Serum cystatin C as a marker of glomerular filtration rateMagdalena Madero
Division of Nephrology, Tufts-New England Medical Center, Boston, Massachusetts, USA
Curr Opin Nephrol Hypertens 15:610-6. 2006..SUMMARY: Cystatin C shows promise as an alternative to serum creatinine but several important questions remain before it can be recommended for use in clinical practice...
The impact of long-term lithium treatment on renal function in an outpatient populationSarah M McCann
Windsor House, Belfast City Hospital Trust Lisburn Road, Belfast, BT9 7AB, UK
Ulster Med J 77:102-5. 2008..This study aims to compare younger and older populations of lithium-treated patients and to examine the impact of long-term lithium treatment on renal function...
Renal failure in high altitude: renal functions, renal pathology and bone mineralization in rats with ablation nephropathy at 1200 m altitudeAlper Soylu
Department of Pediatrics, Medical Faculty, Dokuz Eylul University, Mithatpaşa Cad No 665 4, 35280, Kucukyali, Izmir, Turkey
Pathol Res Pract 203:795-800. 2007..006). In conclusion, exposure to 1200 m altitude, compared to the sea level, preserved the creatinine clearance better in 5/6 nephrectomized rats. No change was observed in proteinuria, renal histopathology, and bone mineralization...
Aortic clamping during elective operations for infrarenal disease: The influence of clamping time on renal functionEric Wahlberg
Department of Surgery, Division of Vascular Surgery, University of California, San Francisco, USA
J Vasc Surg 36:13-8. 2002..The aim of the study was to estimate this risk and possibly identify a "safe" duration of renal ischemia...
[Safe drug prescribing for patients with renal failure]Akio Tanaka
Department of Pharmacy, Chubu Rosai Hospital
Nippon Rinsho 65:58-66. 2007
Creatinine clearance and risk of early mortality in patients undergoing coronary artery bypass graftingMartin J Holzmann
Department of Thoracic Surgery, Karolinska University Hospital, Stockholm, Sweden
J Thorac Cardiovasc Surg 130:746-52. 2005....
Renoprotective effect of chronic adrenomedullin infusion in Dahl salt-sensitive ratsToshio Nishikimi
Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Mibu, Tochigi, Japan
Hypertension 39:1077-82. 2002....
Plasma cystatin C as a marker of renal function in patients with liver cirrhosisE Randers
Department of Internal Medicine, Viborg Kjellerup County Hospital, Viborg, Denmark
Scand J Clin Lab Invest 62:129-34. 2002..03). The results demonstrate that the diagnostic accuracy of plasma cystatin C was better than plasma creatinine in identifying liver cirrhotic patients with reduced glomerular filtration rate...
Tamm-Horsfall protein excretion to predict the onset of renal insufficiencyMaria C Romero
Departmento de Quimica Biologica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, 1428, Ciudad Autonoma de Buenos Aires, Argentina
Clin Biochem 35:65-8. 2002..Immunosuppressive therapy after liver transplantation may be a risk for kidney dysfunction. This work was designed to determine whether Tamm-Horsfall Protein (THP) could be considered as a marker for nephrotoxicity...
Uric acid as a risk factor for progression of non-diabetic chronic kidney disease? The Mild to Moderate Kidney Disease (MMKD) StudyGisela Sturm
Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
Exp Gerontol 43:347-52. 2008..In summary, our prospective 7 year follow-up study in patients with non-diabetic primary CKD did not support uric acid as an independent predictor for CKD progression...
Calculation of the estimated creatinine clearance in avoiding drug dosing errors in the older patientK T Hu
Department of Medicine, University of California Davis, Sacramento, USA
Am J Med Sci 322:133-6. 2001..Estimation of glomerular filtration rate should be performed routinely on all admitted patients older than 80 and in any patient with low lean body mass...
Hyperkalemia, renal failure, and converting-enzyme inhibition: an overrated connectionN H Garcia
IPEM Gambro Healthcare and National University of Cordoba, Cordoba, Argentina
Hypertension 38:639-44. 2001..We conclude that in hemodynamically stable rats with reduced renal mass and renal dysfunction, the administration of an ACE inhibitor does not cause severe hyperkalemia...
Determinants of aciclovir-induced nephrotoxicity in childrenRuth Schreiber
Division of Clinical Pharmacology Toxicology, Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
Paediatr Drugs 10:135-9. 2008..Aciclovir is the drug of choice for severe systemic herpes virus infections. Nephrotoxicity is one of the clinically significant adverse effects of this drug, but studies examining nephrotoxicity in children are scarce...
Uraemic symptoms, nutritional status and renal function in pre-dialysis end-stage renal failure patientsF Caravaca
, Hospital Universitario Infanta Cristina, Badajoz, Spain
Nephrol Dial Transplant 16:776-82. 2001..In contrast, Kt/V urea may be a less sensitive and specific method for assessing the severity of uraemia in ESRD patients...
Correlation between plasma milrinone concentration and renal function in patients with cardiac diseaseM Hasei
Intensive Care Unit, Osaka University Hospital, Osaka, Japan
Acta Anaesthesiol Scand 52:991-6. 2008..The dose of milrinone should be reduced in patients with renal failure. However, there is little data examining the relationship between plasma concentration of milrinone (pCmil) and renal function in intravenous infusion...
Relationship between hematocrit and renal function in men and womenC Y Hsu
Division of Nephrology, University of California, San Francisco, San Francisco, California 94143-0532, USA
Kidney Int 59:725-31. 2001..CONCLUSIONS: A decrease in hematocrit is apparent even among patients with mild to moderate renal insufficiency. At any given level of renal function below estimated C(Cr) 60 mL/min, men have a larger decrease in hematocrit than women...
Gender differences in predictors of the decline of renal function in the general populationNynke Halbesma
Division of Nephrology, Department of Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Kidney Int 74:505-12. 2008..These studies show that there are gender differences in the standard predictors of the decline in renal function...
[Hypertension and the kidney]Katharina Hohenstein
Klinische Abteilung für Nephrologie und Dialyse, Universitätsklinik für Innere Medizin III, Medizinische Universität Wien, Wien, Austria
Wien Med Wochenschr 158:359-64. 2008..This review summarizes current evidence for the role of hypertension and proteinuria with regard to renal and cardiovascular outcomes and for the importance of intensive antihypertensive and anti-proteinuric measures...
[The importance to forewarn or to recommend the indications for renal dialysis]F Navazio
Department of Integrative Biology, 5101 VLSB, University of California at Berkeley, CA 94720-3140, USA
Clin Ter 153:187-8. 2002
Pre-operative renal function predicts development of chronic renal insufficiency after orthotopic heart transplantationMark R Vossler
Oregon Cardiac Transplant Program, Division of Cardiology, Oregon Health Sciences University, Portland 97201, USA
J Heart Lung Transplant 21:874-81. 2002..CONCLUSION: Pre-operative serum creatinine concentration predicts development of renal insufficiency after heart transplantation...
Acetylcysteine for prevention of acute deterioration of renal function following elective coronary angiography and intervention: a randomized controlled trialJay Kay
Cardiac Medical Unit, Grantham Hospital, 125 Wong Chuk Hang Rd, Aberdeen, Hong Kong
JAMA 289:553-8. 2003..The antioxidant acetylcysteine prevents acute contrast nephrotoxicity in patients with impaired renal function who undergo computed tomography scanning. However, its role in coronary angiography is unclear...
Incidence of radiocontrast nephropathy in patients undergoing acute stroke computed tomography angiographyAndrea L Krol
Stroke 38:2364-6. 2007..CONCLUSIONS: Overall, these results illustrate that there is a low incidence of RCN in acute stroke patients undergoing emergency CTA...
Unexpectedly high prevalence of posttransplant anemia in pediatric and young adult renal transplant recipientsPeter D Yorgin
Section of Pediatric Nephrology, Department of Pediatrics, Lucile Salter Packard Children s Hospital, Stanford University, Stanford, CA 94304, USA
Am J Kidney Dis 40:1306-18. 2002..Although posttransplant anemia (PTA) is recognized as a common problem in adult renal transplant recipients, few pediatric studies have been published...
Pharmacokinetics of pregabalin in subjects with various degrees of renal functionEdward J Randinitis
Clinical Sciences Department, Pfizer Global Research and Development, 2800 Plymouth Road, Ann Arbor, MI 48105, USA
J Clin Pharmacol 43:277-83. 2003..Supplemental pregabalin doses may be required for patients on chronic hemodialysis treatment after each hemodialysis treatment to maintain steady-state plasma pregabalin concentrations within desired ranges...
[Postoperative renal failure and its risk factors after open heart surgery]Erzsébet Feiler
Zala Megyei Kórház, Szívsebészeti Osztály
Orv Hetil 144:799-802. 2003..In this retrospective study the authors have investigated the occurrence and the possible risk factors of renal failure following heart surgery on CPB...
Urinary proteins in multiple myeloma: correlation with clinical parameters and diagnostic implicationsA Corso
Institute of Hematology, IRCCS Policlinico San Matteo, University of Pavia, 27100, Pavia, Italy
Ann Hematol 82:487-91. 2003....
Clinical utility of cardiac troponin I in the diagnosis of acute coronary syndrome in patients with renal failureSaravanan Balamuthusamy
Department of Medicine and Cardiology, Chicago Medical School at Rosalind Franklin University, Chicago, IL, USA
Am J Ther 14:356-60. 2007..cTnI has a sensitivity of 60% and specificity of 71% in acute coronary syndrome patients with renal insufficiency. In patients on hemodialysis, troponin I has a sensitivity of 73% and specificity of 83% for detection of obstructive CAD...
Nephropathy requiring dialysis after percutaneous coronary intervention and the critical role of an adjusted contrast doseRosario V Freeman
Division of Cardiology, University of Washington, Seattle, Washington, USA
Am J Cardiol 90:1068-73. 2002..A risk prediction tool for NRD with guidelines for prevention is presented...
[Risky medication and contrast media-induced nephropathy in patients with diabetes and hypertension]D Krusová
II interní klinika Lékarské fakulty MU a FN u sv Anny, Brno
Vnitr Lek 52:1014-20. 2006..g. elimination of risky medication and in indicated cases, taking preventive measures...
Long-term renal function preservation after renal artery stenting in patients with progressive ischemic nephropathyKrishna J Rocha-Singh
Prairie Heart Institute at St John s Hospital and Prairie Education and Research Cooperative, Department of Cardiology, Southern Illinois University School of Medicine, Springfield, Illinois 62794, USA
Catheter Cardiovasc Interv 57:135-41. 2002..Renal stent revascularization should be considered a valid therapeutic option for the long-term treatment of ischemic nephropathy...
[Nephrogenic systemic fibrosis]W Samtleben
Schwerpunkt Nephrologie, Medizinische Klinik und Poliklinik I, Klinikum Grosshadern der Ludwig Maximilians Universität München, Marchioninistrasse 15, 81377 Munchen, Deutschland
Radiologe 47:778-84. 2007....
C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunctionChristoph Caliezi
Central Laboratory of Hematology, University Hospital, Inselspital, Bern, Switzerland
Crit Care Med 30:1722-8. 2002..Mortality rate was similar in both groups. There were no C1-inhibitor-related side effects. CONCLUSIONS: C1-inhibitor administration attenuated renal impairment in patients with severe sepsis or septic shock...
Effects of a diet rich in advanced glycation end products in the rat remnant kidney modelKatarina Sebekova
Institute of Preventive and Clinical Medicine, Bratislava, Slovak Republic
Am J Kidney Dis 41:S48-51. 2003..Although bioactivity of orally absorbed MRPs has been shown in both experimental and human studies, its relevance in renal insufficiency still is unclear...
[Hepatitis C viral in patients with terminal chronic kidney failure. I. Prevalence]L Gonzalez-Michaca
Departamento de Nefrologia y Metabolismo Mineral, Instituto Nacional de la Nutricion Salvador Zubiran
Rev Invest Clin 52:246-54. 2000..Thus, the major goals of the present study were to determine the prevalence of hepatitis C in our patients on dialysis, and the risk factors associated with it...
A decade of experience with renal transplantation in African-AmericansClarence E Foster
Division of Transplantation, Department of Surgery, School of Medicine, University of Maryland, Baltimore, Maryland 210201, USA
Ann Surg 236:794-804; discussion 804-805. 2002..Once kidney failure has developed, African-Americans are disadvantaged for the following reasons: this patient cohort has longer ..
The dental health status of dialysis patientsJudith T Klassen
Division of Nephrology, St Paul s Hospital, 1702 20th Street West, Saskatoon, SK, Canada
J Can Dent Assoc 68:34-8. 2002The number of patients with kidney failure who require dialysis is growing by 10% to 15% annually, and the likelihood that dentists will treat such patients is also increasing...
[Studies on the kidney and the renal circulation, by Josep Trueta i Raspall (1897-1977)]Fariña L A Pérez
Servicio de Urologia, Hospital POVISA, Vigo, Pontevedra
Actas Urol Esp 32:276-80. 2008..One of the most outstanding fruits of this investigation is the book "Studies on renal circulation", first published in English in 1947 (Oxford), then in Spanish in 1949 (Barcelona)...
Electrochemistry in diabetes managementAdam Heller
Department of Chemical Engineering, University of Texas, Austin, Texas 78712, USA
Acc Chem Res 43:963-73. 2010..Periods of hyperglycemia (high glucose) cause circulatory disease, stroke, amputations, blindness, kidney failure and nerve degeneration...
Caspofungin versus amphotericin B for candidemia: a pharmacoeconomic analysisJohn R Wingard
University of Florida College of Medicine, Gainesville, 32610, USA
Clin Ther 27:960-9. 2005..7% and 62.8% of patients, respectively) and exhibited a generally better safety profile, particularly with respect to impaired renal function (IRF) (P = 0.02)...
Italian multicenter study on complications of laparoscopic myomectomyOrnella Sizzi
Villa Valeria Hospital, Rome, Italy
J Minim Invasive Gynecol 14:453-62. 2007..To study intraoperative and postoperative complications of laparoscopic myomectomy and patients' characteristics influencing this risk...
Human cytomegalovirus: detection of congenital and perinatal infection in ArgentinaAngélica Lidia Distéfano
Department of Virology, Laboratorio de Virosis Congénitas Perinatales y Transmisión Sexual, Instituto Nacional de Microbiología INEI ANLIS Carlos G, Malbran, Ministerio de Salud de la Nación, Av, CP 1281, Buenos Aires, Argentina
BMC Pediatr 4:11. 2004..Results were compared with IgM detection...
[Regeneration capacity of skeletal muscle]A Wernig
Physiologisches Institut, Universitat Bonn
Ther Umsch 60:383-9. 2003..may decide to change his/her (locomotor) behaviour by severe onset of jogging; it may happen that they suffer kidney failure on Monday due to muscle microdamage and the transfer of myoproteins into the serum over weekend...
Research Grants
- Genetic contributors to diabetes and dyslipidemia in African AmericansMichele Sale; Fiscal Year: 2009..million African Americans, and leads to a devastating range of complications, including heart attack, stroke, kidney failure, blindness, amputation, and nerve pain...
- Hypertension PharmacogeneticsJulie Johnson; Fiscal Year: 2006..in the United States, and is a leading cause of stroke, acute myocardial infarction (MI), heart failure and kidney failure. There are numerous effective antihypertensive drug classes, but only about half of patients have a good ..
- Glucose monitoring using polarized lightGERARD COTE; Fiscal Year: 2007..tighter control, and fewer secondary complications from diabetes mellitus, such as heart disease, blindness, kidney failure, gangrene, and blindness...
- Glucose monitoring using polarized lightGerard L Cote; Fiscal Year: 2010..tighter control, and fewer secondary complications from diabetes mellitus, such as heart disease, blindness, kidney failure, gangrene, and blindness...
- Pathogenicity of Shiga Toxin-Producing E. coliALISON O BRIEN; Fiscal Year: 2007..the hemolytic uremic syndrome (HUS), a sequela of O 157:H7 infection, is the most frequent basis for acute kidney failure in U.S. children...
- Role of Mineralocorticoid Receptor in Diabetic Cardiovascular DiseaseGAIL ADLER; Fiscal Year: 2009..Vascular injury leads to many health problems including heart damage, kidney failure, stroke, blindness and poor circulation in the legs...
- S.T.R.A.P Sonos Transportable Renal Application ProductMartin Roberts; Fiscal Year: 2005..Compliance is low for this intense procedure, and the treatment becomes inadequate with complete kidney failure, requiring a transfer to hemodialysis. Unfortunately, mortality with either technique is over 20% per year...
- The Role of BMP-7 in Chronic Kidney DiseaseKeith Hruska; Fiscal Year: 2005..A second hypothesis to be tested is that replacement of BMP-7 in chronic kidney failure will maintain bone remodeling rates in the absence of secondary hyperparathyroidism...
- Gene-engineered dendritic cell therapy for diabeticsMassimo Trucco; Fiscal Year: 2006..However, these strategies can lead to an array of other problems including kidney failure and a risk of malignancy...
- Genome-wide fine-mapping of metabolic traits in heterogeneous stock ratsLEAH CATHERINE SOLBERG WOODS; Fiscal Year: 2010..T2D is a leading cause of kidney failure, blindness and limb amputation and a major risk factor for heart disease and stroke (18)...
- Kidney Function, Aortic Stiffness and AgingAndrew S Levey; Fiscal Year: 2010Chronic kidney disease (CKD) is an important health problem in the elderly, with an increasing incidence of kidney failure and a high prevalence of earlier stages of CKD, with poor outcomes and high cost...
- Kidney Function, Aortic Stiffness and AgingAndrew S Levey; Fiscal Year: 2010Chronic kidney disease (CKD) is an important health problem in the elderly, with an increasing incidence of kidney failure and a high prevalence of earlier stages of CKD, with poor outcomes and high cost...
- Prevention of Type I Diabetes Mellitus using a Cell Vac*Nick Giannoukakis; Fiscal Year: 2002..and consequently, many patients eventually succumb to debilitating and life-threatening complications such as kidney failure and heart disease...
- NO-donor/SOD-mimetics for diabetic nephropathyELWOOD REYNOLDS; Fiscal Year: 2007..Diabetes is the most common cause of kidney failure in the U.S...
- Improving Kidney Transplant Outcome with a Novel Complement InhibitorSHELLEY MAVES; Fiscal Year: 2007For the greater than 100,000 Americans who suffer from kidney failure each year, transplantation is their best treatment option...
- Cellular Physiology of PodocytesSTUART DRYER; Fiscal Year: 2009..Diabetic nephropathy is the leading cause of kidney failure in the developed world...
- Cellular Physiology of PodocytesStuart E Dryer; Fiscal Year: 2010..Diabetic nephropathy is the leading cause of kidney failure in the developed world...
- The Pathogenesis of Sickle Cell NephropathyAntonio Guasch; Fiscal Year: 2010..is a common complication of sickle cell disease that affects both children and adults, and may lead to kidney failure. The mechanisms that cause kidney damage in sickle cell disease are not well understood...
- The Pathogenesis of Sickle Cell NephropathyAntonio Guasch; Fiscal Year: 2010..is a common complication of sickle cell disease that affects both children and adults, and may lead to kidney failure. The mechanisms that cause kidney damage in sickle cell disease are not well understood...
- RENIN ANGIOTENSIN SYSTEM BLOCKAGE--DIABETIC NEPHROPATHYS Mauer; Fiscal Year: 2003DESCRIPTION (Taken in part from applicant's abstract) Diabetic nephropathy is the most common cause of kidney failure in the United States, particularly for those individuals with type I diabetes (IDDM)...
- The role of Macrophage Delivered WNT Signaling in kidney injury and repairJEREMY DUFFIELD; Fiscal Year: 2009..the normal repair process in the kidney and in directing the development of fibrosis, which is a harbinger of kidney failure. We have discovered that the Canonical WNT cell-to-cell signaling pathway, that regulates cell survival, ..
- The role of Macrophage Delivered WNT Signaling in kidney injury and repairJeremy S Duffield; Fiscal Year: 2010..the normal repair process in the kidney and in directing the development of fibrosis, which is a harbinger of kidney failure. We have discovered that the Canonical WNT cell-to-cell signaling pathway, that regulates cell survival, ..
- TISSUE SPECIFIC NUTRITIONAL ADAPTATIONS IN RENAL FAILURES Price; Fiscal Year: 1999..Besides protein intake, acidosis accelerates BCAA catabolism; correction of the acidosis of kidney failure normalizes whole-body leucine oxidation...
- Regulation of CD32A in neutrophilsPeriasamy Selvaraj; Fiscal Year: 2003..Such a tissue injury also results in glomerulonephritis leading to kidney failure and death in these disease states...
- Regulation of CD32A in neutrophilsPeriasamy Selvaraj; Fiscal Year: 2007..Such a tissue injury also results in glomerulonephritis leading to kidney failure and death in these disease states...
- Regulation of CD32A in neutrophilsPeriasamy Selvaraj; Fiscal Year: 2006..Such a tissue injury also results in glomerulonephritis leading to kidney failure and death in these disease states...
