smear layer

Summary

Summary: Adherent debris produced when cutting the enamel or dentin in cavity preparation. It is about 1 micron thick and its composition reflects the underlying dentin, although different quantities and qualities of smear layer can be produced by the various instrumentation techniques. Its function is presumed to be protective, as it lowers dentin permeability. However, it masks the underlying dentin and interferes with attempts to bond dental material to the dentin.

Top Publications

  1. ncbi Surface debris of canal walls after post space preparation in endodontically treated teeth: a scanning electron microscopic study
    Cinzia Serafino
    Department of Dental Materials, University of Siena, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:381-7. 2004
  2. ncbi Shear bond strength of glass-ionomer adhesive to dentin: effect of smear layer thickness and different dentin conditioners
    Farid S El-Askary
    Conservative Dentistry Department, Faculty of Dentistry, Ain Shams University, Egypt
    J Adhes Dent 10:471-9. 2008
  3. ncbi Effects of rotary instrumentation and different etchants on removal of smear layer on human dentin
    M F Ayad
    College of Dentistry, University of Tanta, Tanta, Egypt
    J Prosthet Dent 85:67-72. 2001
  4. ncbi Shear bond strength of three resin based sealers to dentin with and without the smear layer
    Ayce Unverdi Eldeniz
    Department of Endodontics, Faculty of Dentistry, University of Selcuk, Konya, Turkey
    J Endod 31:293-6. 2005
  5. ncbi The effect of German chamomile (Marticaria recutita L.) extract and tea tree (Melaleuca alternifolia L.) oil used as irrigants on removal of smear layer: a scanning electron microscopy study
    M S Sadr Lahijani
    Research School of Biological Science, Australian National University
    Int Endod J 39:190-5. 2006
  6. ncbi Conditioning effect on dentin, resin tags and hybrid layer of different acidity self-etch adhesives applied to thick and thin smear layer
    Silvia Kenshima
    University of Sao Paulo, FOUSP, Dental Materials Department, Av Professor Lineu Prestes, 2227, Cidade Universitaria, CEP 05508 000, Sao Paulo, SP, Brazil
    J Dent 34:775-83. 2006
  7. ncbi A comparative study of smear layer removal and erosion in apical intraradicular dentine with three irrigating solutions: a scanning electron microscopy evaluation
    Manuele Mancini
    Department of Restorative Dentistry and Endodontics, University of Rome Tor Vergata, Rome, Italy
    J Endod 35:900-3. 2009
  8. ncbi A scanning electron microscopic study of debris and smear layer remaining following use of GT rotary instruments
    G Gambarini
    Department of Periodontics-Endodontics, University of Rome, La Sapienza, Rome, Italy
    Int Endod J 35:422-7. 2002
  9. ncbi The effect of two different root canal sealers and smear layer on resistance to root fracture
    Funda Kont Cobankara
    Department of Endodontics, Faculty of Dentistry, , Konya, Turkey
    J Endod 28:606-9. 2002
  10. ncbi Influence of final rinse technique on ability of ethylenediaminetetraacetic acid of removing smear layer
    Isabel Mello
    Department of Restorative Dentistry, Faculty of Dentistry, University of Manitoba, Winnipeg, Manitoba, Canada
    J Endod 36:512-4. 2010

Detail Information

Publications183 found, 100 shown here

  1. ncbi Surface debris of canal walls after post space preparation in endodontically treated teeth: a scanning electron microscopic study
    Cinzia Serafino
    Department of Dental Materials, University of Siena, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:381-7. 2004
    ..Amount of debris, smear layer, sealer/gutta-percha remnants, and visibility of open tubules were rated...
  2. ncbi Shear bond strength of glass-ionomer adhesive to dentin: effect of smear layer thickness and different dentin conditioners
    Farid S El-Askary
    Conservative Dentistry Department, Faculty of Dentistry, Ain Shams University, Egypt
    J Adhes Dent 10:471-9. 2008
    To investigate the effect of two different smear layer thicknesses treated with different dentin conditioners on the bond strength of glass-ionomer adhesive to dentin.
  3. ncbi Effects of rotary instrumentation and different etchants on removal of smear layer on human dentin
    M F Ayad
    College of Dentistry, University of Tanta, Tanta, Egypt
    J Prosthet Dent 85:67-72. 2001
    ..Various methods of rotary preparation and conditioning of teeth affect surface topography and may affect the retention of dental restorations...
  4. ncbi Shear bond strength of three resin based sealers to dentin with and without the smear layer
    Ayce Unverdi Eldeniz
    Department of Endodontics, Faculty of Dentistry, University of Selcuk, Konya, Turkey
    J Endod 31:293-6. 2005
    ..The coronal two thirds of ninety extracted human third molars were removed. The smear layer of the exposed dentin surfaces were removed using 17% EDTA followed by 5...
  5. ncbi The effect of German chamomile (Marticaria recutita L.) extract and tea tree (Melaleuca alternifolia L.) oil used as irrigants on removal of smear layer: a scanning electron microscopy study
    M S Sadr Lahijani
    Research School of Biological Science, Australian National University
    Int Endod J 39:190-5. 2006
    To compare the cleaning effectiveness of chamomile hydroalcoholic extract and tea tree oil to 2.5% sodium hypochlorite (NaOCl) solution as an intracanal irrigant for the removal of the smear layer.
  6. ncbi Conditioning effect on dentin, resin tags and hybrid layer of different acidity self-etch adhesives applied to thick and thin smear layer
    Silvia Kenshima
    University of Sao Paulo, FOUSP, Dental Materials Department, Av Professor Lineu Prestes, 2227, Cidade Universitaria, CEP 05508 000, Sao Paulo, SP, Brazil
    J Dent 34:775-83. 2006
    to assess the conditioning effect (CE) of self-etch adhesives of different acidity applied to thick and thin smear layer (SL), the corresponding resin tags (RT) and hybrid layer (HL).
  7. ncbi A comparative study of smear layer removal and erosion in apical intraradicular dentine with three irrigating solutions: a scanning electron microscopy evaluation
    Manuele Mancini
    Department of Restorative Dentistry and Endodontics, University of Rome Tor Vergata, Rome, Italy
    J Endod 35:900-3. 2009
    This study compared the efficacy of BioPure MTAD (Dentsply Tulsa, Tulsa, OK), 17% EDTA, and 42% citric acid in endodontic smear layer removal and degree of erosion in the apical third of endodontic canals.
  8. ncbi A scanning electron microscopic study of debris and smear layer remaining following use of GT rotary instruments
    G Gambarini
    Department of Periodontics-Endodontics, University of Rome, La Sapienza, Rome, Italy
    Int Endod J 35:422-7. 2002
    AIM: The aim of the present study was to assess debris and smear layer remaining following canal preparation with GT rotary instruments...
  9. ncbi The effect of two different root canal sealers and smear layer on resistance to root fracture
    Funda Kont Cobankara
    Department of Endodontics, Faculty of Dentistry, , Konya, Turkey
    J Endod 28:606-9. 2002
    ..test the effect of Ketac-Endo (KE) and AH 26 on resistance to root fracture and also to evaluate the effect of smear layer. Seventy-two human maxillary canine teeth were randomly divided into six groups (n = 12) and were prepared ..
  10. ncbi Influence of final rinse technique on ability of ethylenediaminetetraacetic acid of removing smear layer
    Isabel Mello
    Department of Restorative Dentistry, Faculty of Dentistry, University of Manitoba, Winnipeg, Manitoba, Canada
    J Endod 36:512-4. 2010
    ..The aim of this study was to verify the impact of the final rinse technique on smear layer removal ability of 17% ethylenediaminetetraacetic acid (EDTA).
  11. ncbi Evaluation of smear layer removal by EDTAC and sodium hypochlorite with ultrasonic agitation
    D M Z Guerisoli
    , , , Brazil
    Int Endod J 35:418-21. 2002
    AIM: To evaluate smear layer removal by different irrigating solutions under ultrasonic agitation. METHODOLOGY: Twenty recently extracted mandibular incisors with a single root canal were divided into four equal groups...
  12. ncbi Effect of shortened irrigation times with 17% ethylene diamine tetra-acetic acid on smear layer removal after rotary canal instrumentation
    Koichi Saito
    Naval Postgraduate Dental School, Bethesda, Maryland, USA
    J Endod 34:1011-4. 2008
    ..times of 1 minute or less with 1 mL of 17% ethylene diamine tetra-acetic acid (EDTA) effectively removed the smear layer from root canals after rotary instrumentation...
  13. ncbi Effect of smear layer thickness and pH of self-etching adhesive systems on the bond strength and gap formation to dentin
    Silvia Kenshima
    Department of Dental Materials, , , Brazil
    J Adhes Dent 7:117-26. 2005
    PURPOSE: To measure the buffering capacity of self-etching adhesive systems and to evaluate the effect of smear layer thickness on the mean gap width (GW) and microtensile bond strength (microBS) to dentin of these self-etching adhesives...
  14. ncbi Smear layer production by 3 rotary reamers with different cutting blade designs in straight root canals: a scanning electron microscopic study
    In-Soo Jeon
    Yonsei University, Department of Endodontics, College of Dentistry, Oral Science Research Center, Seoul, South Korea
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:601-7. 2003
    ..The aim of this scanning electron microscopic study was to compare the quality and amount of smear layer generated in the apical third of straight root canals by 2 rotary nickel-titanium reamers and 1 rotary steel ..
  15. ncbi The effect of EDTA with and without ultrasonics on removal of the smear layer
    Hong Guan Kuah
    Department of Restorative Dentistry, National Dental Centre of Singapore, Singapore
    J Endod 35:393-6. 2009
    This study evaluated in vitro effectiveness of 17% EDTA with and without ultrasonics on smear layer removal...
  16. ncbi A new solution for the removal of the smear layer
    Mahmoud Torabinejad
    Department of Endodontics, School of Dentistry, Loma Linda University, CA 92350, USA
    J Endod 29:170-5. 2003
    Various organic acids, ultrasonic instruments, and lasers have been used to remove the smear layer from the surface of instrumented root canals...
  17. ncbi Effect of smear layer thickness on bond strength mediated by three all-in-one self-etching priming adhesives
    Chihiro Tani
    Department of Operative Dentistry, Showa University, School of Dentistry, Tokyo, Japan
    J Adhes Dent 4:283-9. 2002
    ..The smear layer thickness (SLT) was measured microscopically...
  18. ncbi The effect of various concentrations of sodium hypochlorite on the ability of MTAD to remove the smear layer
    Mahmoud Torabinejad
    Endodontic Residency Program, School of Dentistry, Loma Linda University, CA 92350, USA
    J Endod 29:233-9. 2003
    Various organic acids, ultrasonic instruments, and lasers have been used to remove the smear layer from the surface of instrumented root canals...
  19. ncbi Effect of different irrigation on smear layer removal after post space preparation
    Xin Hua Gu
    Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, PR China
    J Endod 35:583-6. 2009
    The purpose of this study was to evaluate the effect of different irrigating solutions on smear layer removal and dentinal tubule opening on root canal surfaces after post space preparation and to study whether additional ultrasonic ..
  20. ncbi Comparison of the efficacy of maleic acid and ethylenediaminetetraacetic acid in smear layer removal from instrumented human root canal: a scanning electron microscopic study
    Nidambur Vasudev Ballal
    Manipal College of Dental Sciences, Karnataka, India
    J Endod 35:1573-6. 2009
    The aim of this study was to assess, by scanning electron microscopic (SEM) analysis, the ability of 17% EDTA and 7% maleic acid in the removal of the smear layer from the human root canal system.
  21. ncbi Light and scanning electron microscopic evaluation of Glyde File Prep in smear layer removal
    T S Lim
    Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Republic of Singapore
    Int Endod J 36:336-43. 2003
    ..the effectiveness of Glyde File Prep used in conjunction with sodium hypochlorite irrigation in the removal of smear layer produced during root canal instrumentation...
  22. ncbi Effect of removal of the smear layer on apical microleakage
    S Timpawat
    Department of Operative Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    J Endod 27:351-3. 2001
    It has been shown previously that the smear layer created during instrumentation of the root canal promotes apical microleakage...
  23. ncbi The influence of the smear layer on dentinal tubule penetration depth by three different root canal sealers: an in vitro study
    Andreas B Kokkas
    Department of Endodontology, School of Dentistry, Aristotle University, Thessaloniki, Greece
    J Endod 30:100-2. 2004
    The effect of the smear layer on the penetration depth of three different root canal sealers into the dentinal tubules was examined in 64 recently extracted single-rooted teeth...
  24. ncbi Clinical implications of the smear layer in endodontics: a review
    Mahmoud Torabinejad
    Department of Endodontics, School of Dentistry, Loma Linda University, CA 92350, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:658-66. 2002
    It has been recognized for many years that root canal instrumentation produces a smear layer that covers the surfaces of prepared canal walls...
  25. ncbi Long-term evaluation of the influence of smear layer on the apical sealing ability of MTA
    Tahsin Yildirim
    Faculty of Dentistry, Department of Restorative Dentistry, Karadeniz Technical University, Trabzon, Turkey
    J Endod 34:1537-40. 2008
    The aim of this in vitro study was to investigate the effect of the smear layer on apical microleakage in teeth obturated with mineral trioxide aggregate (MTA). Fifty single-rooted central maxillary teeth were used in this study...
  26. ncbi Bacterial penetration along different root canal filling materials in the presence or absence of smear layer
    I M Saleh
    Department of Endodontics, Faculty of Dentistry, University of Oslo, Oslo, Norway
    Int Endod J 41:32-40. 2008
    To study the effect of the smear layer on the penetration of bacteria along different root canal filling materials and to examine the dentine/sealer and sealer/core material interfaces for the presence of bacteria.
  27. ncbi Wettability and bonding of self-etching dental adhesives. Influence of the smear layer
    Jose A Aguilar-Mendoza
    Biocolloid and Fluid Physics Group, Department of Applied Physics, University of Granada, Spain
    Dent Mater 24:994-1000. 2008
    To evaluate dentin wettability and bonding of self-etching and total-etch adhesives on smear layer-covered and smear layer-free dentin.
  28. ncbi The influence of the dentin smear layer on adhesion: a self-etching primer vs. a total-etch system
    Sofia S A Oliveira
    Department of Preventive and Restorative Dental Sciences, University of California, 707 Parnassus Avenue D2246, San Francisco, CA 94143-0758, USA
    Dent Mater 19:758-67. 2003
    ..Surface roughness and smear layer thickness varied strongly with coarseness...
  29. ncbi Evaluation of the influence of smear layer on the apical and coronal sealing ability of two sealers
    Funda Kont Cobankara
    Department of Endodontics, Faculty of Dentistry, Selcuk University, Campus 42075, Konya, Turkey
    J Endod 30:406-9. 2004
    The aim of this in vitro study was to determine the effect of the smear layer on apical and coronal leakage in root canals obturated with AH26 or RoekoSeal sealers...
  30. ncbi Effect of a low-concentration EDTA solution on root canal walls: a scanning electron microscopic study
    Fabienne Perez
    Faculty of Odontology, Department of Endodontics, University of Bordeaux, France
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:383-7. 2005
    ..The aim of this study was to evaluate, in vitro, the ability of an 8% EDTA solution to remove debris and smear produced during root canal preparation...
  31. ncbi Dentine demineralization when subjected to EDTA with or without various wetting agents: a co-site digital optical microscopy study
    G De-Deus
    Department of Endodontics, Veiga de Almeida University, Rio de Janeiro, Brazil
    Int Endod J 41:279-87. 2008
    ..To analyse quantitatively the chelating ability of ethylenediaminetetraacetic acid (EDTA) and three common EDTA-based associations with wetting agents...
  32. ncbi The effect of treatment of radicular dentin on colonization patterns of C. albicans
    B Tugba Turk
    Assistant Professor, Department of Restorative Dentistry and Endodontology, School of Dentistry, Ege University, Izmir, Turkey
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 106:457-62. 2008
    ..The aim of this study was to observe the colonization pattern of C. albicans on treated and untreated radicular dentin...
  33. ncbi Evaluation of the interaction between sodium hypochlorite and chlorhexidine gluconate and its effect on root dentin
    Tung B Bui
    Department of Endodontology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Endod 34:181-5. 2008
    ..The NaOCl/CHX precipitate tends to occlude the dentinal tubules. Until this precipitate is studied further, caution should be exercised when irrigating with NaOCl and CHX...
  34. ncbi Longitudinal and quantitative evaluation of dentin demineralization when subjected to EDTA, EDTAC, and citric acid: a co-site digital optical microscopy study
    Gustavo De-Deus
    Department of Endodontics, Veiga de Almeida University UVA, Rio de Janeiro, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:391-7. 2008
    ..In the present study the chelating power of EDTA, EDTAC, and 1% citric acid (CA) on radicular dentin was quantitatively analyzed...
  35. ncbi SEM evaluation of canal wall dentine following use of Mtwo and ProTaper NiTi rotary instruments
    F Foschi
    Endodontic Unit, Department of Dental Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy
    Int Endod J 37:832-9. 2004
    ..The canal wall of each sample was assessed and compared using a predefined scale of four parameters, namely, smear layer, pulpal debris, inorganic dentine debris, surface profile...
  36. ncbi Decalcifying effect of 15% EDTA, 15% citric acid, 5% phosphoric acid and 2.5% sodium hypochlorite on root canal dentine
    M Pérez-Heredia
    Department of Dental Pathology and Therapeutics, School of Dentistry, University of Granada, Spain
    Int Endod J 41:418-23. 2008
    ..To evaluate and compare ex vivo the decalcifying effect of 15% EDTA, 15% citric acid, 5% phosphoric acid and 2.5% sodium hypochlorite on root canal dentine...
  37. ncbi A scanning electron microscopy evaluation of different root canal irrigating solutions
    María Luisa de la Casa
    Department of Endodontics, Faculty of Dentistry, National University of Tucuman, Argentina
    Acta Odontol Latinoam 18:57-61. 2005
    The efficacy of solutions to remove the smear layer from human teeth was evaluated. One and 2.5% sodium hypochlorite, 1 and 5% calcium hydroxide, 0...
  38. ncbi Water movement in the hybrid layer after different dentin treatments
    Stefano Chersoni
    Department of Dental Sciences, School of Dentistry, University of Bologna, Via San Vitale 59, 40125, Italy
    Dent Mater 20:796-803. 2004
    ..The droplets observed in this region support the hypothesis that there can be bidirectional water movement within the adhesive-HL complex...
  39. ncbi The effect on coronal leakage of liquid adhesive application over root fillings after smear layer removal with EDTA or Er:YAG laser
    Fabricio Dias de Souza
    University of São Paulo Faculty of Dentistry, Ribeirao Preto, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:125-8. 2005
    ..To evaluate coronal microleakage in filled root canals that received different biomechanical preparations and application of liquid adhesives over the root filling and the pulp chamber walls...
  40. ncbi Effect of sodium hypochlorite treatment on the molecular composition and morphology of human coronal dentin
    George Mountouris
    Department of Operative Dentistry, University of Athens, School of Dentistry, Athens, Greece
    J Adhes Dent 6:175-82. 2004
    ....
  41. ncbi Dentin demineralization when subjected to BioPure MTAD: a longitudinal and quantitative assessment
    Gustavo De Deus
    Veiga de Almeida University, Rio de Janeiro, Brazil
    J Endod 33:1364-8. 2007
    ..3 mm thick disks were obtained at the root cervical third from 9 maxillary human molars, and a standardized smear layer was produced. Cosite images of the dentin surface were obtained after several cumulative demineralization times...
  42. ncbi Lactic acid root canal irrigation for dowel and core treatment: a pilot study
    Mohamed F Ayad
    College of Dentistry, University of Tanta, 9 El Geish St, Tanta, 3111, Egypt
    J Prosthet Dent 92:540-5. 2004
    Various solutions used to irrigate root canals and remove the smear layer prior to obturation of a root canal affect surface topography and may influence the sealing ability of endodontic therapy, retention of endodontic dowels, and ..
  43. ncbi Effect of pH modified EDTA solution to the properties of dentin
    Kaoru Nakashima
    Department of Operative Dentistry and Endodontics, School of Dentistry, Iwate Medical University, Iwate, Japan
    J Endod 31:47-9. 2005
    The purpose of this study was to evaluate the influence of smear layer removal with 3% EDTA solution (pH of 9...
  44. ncbi The effect of application time of EDTA and NaOCl on intracanal smear layer removal: an SEM analysis
    C S Teixeira
    Dental School, Federal University of Santa Catarina, Florianopolis, Brazil
    Int Endod J 38:285-90. 2005
    To verify, under the scanning electron microscope (SEM), the influence of irrigation time with ethylenediaminetetraacetic acid (EDTA) and sodium hypochlorite (NaOCl) on intracanal smear layer removal.
  45. ncbi Effectiveness in cleaning oval-shaped root canals using Anatomic Endodontic Technology, ProFile and manual instrumentation: a scanning electron microscopic study
    O Zmener
    Department of Adult Dental Care, Section of Endodontics, Faculty of Odontology University of Buenos Aires, Buenos Aires, Argentina
    Int Endod J 38:356-63. 2005
    ..The presence of debris and smear layer was recorded at distances of 1, 5 and 10 mm from the working length using a three-step scoring scale and a 300 ..
  46. ncbi Efficacy of EDTA-T gel for smear layer removal at root surfaces
    Luiz Henrique Carvalho Batista
    Department of Periodontology, Dental School of Araraquara, , Araraquara, SP, Brazil
    Quintessence Int 36:551-8. 2005
    ..investigate the efficacy of EDTA gel preparation, associated with texapon detergent (EDTA-T), for removing the smear layer at human root surfaces...
  47. ncbi Ultrastructure of smear layer-covered intraradicular dentin after irrigation with BioPure MTAD
    Franklin R Tay
    Pediatric Dentistry and Orthodontics, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    J Endod 32:218-21. 2006
    ..However, the potential consequences of compaction of hydrophobic sealers against air-dried, collapsed collagen matrices, and hydrolytic degradation of incompletely infiltrated matrices remain unresolved...
  48. ncbi Cleaning and shaping the root canal with a Nd:YAG laser beam: a comparative study
    G Levy
    Marseille University, Marseille, France
    J Endod 18:123-7. 1992
    ..Scanning electron microscopic evaluations showed that preparation with a laser beam is possible and results in an improvement in the cleanliness of the canal walls when compared with conventional techniques...
  49. ncbi Evaluation of the surface free energy on root canal dentine walls treated with chelating agents and NaOCl
    H Dogan Buzoglu
    Department of Endodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey
    Int Endod J 40:18-24. 2007
    ..To evaluate ex vivo the effects of combined and single use of EDTA, RC-Prep and NaOCl on the surface free energy of canal wall dentine using the captive bubble technique...
  50. ncbi Root canal irrigants
    Matthias Zehnder
    Department of Preventive Dentistry, Periodontology, and Cariology, Division of Endodontology, University of Zürich Center for Dental Medicine, Switzerland
    J Endod 32:389-98. 2006
    ..In addition, chelating solutions are recommended as adjunct irrigants to prevent the formation of a smear layer and/or remove it before filling the root canal system...
  51. ncbi A scanning electron microscopic study of debris and smear layer remaining following use of AET instruments and K-flexofiles
    Saulius Drukteinis
    Institute of Odontology, Faculty of Medicine, Vilnius University, Zalgirio 115, 08217 Vilnius, Lithuania
    Stomatologija 8:70-5. 2006
    ..To compare in vitro the cleanliness of root canal walls following automated or manual instrumentation...
  52. ncbi The influence of canal curvature on the mechanical efficacy of root canal irrigation in vitro using real-time imaging of bioluminescent bacteria
    Donald Nguy
    Department of Cariology, Restorative Sciences and Endodontics, University of Michigan, School of Dentistry, Ann Arbor, Michigan 48409-1078, USA
    J Endod 32:1077-80. 2006
    ..Irrigation was significantly less effective in 24 to 28 degrees curvature canals prepared to size 27/.04 compared to 46/.04 (p < 0.007, repeated-measures ANOVA)...
  53. ncbi Push-out bond strengths: the Epiphany-Resilon endodontic obturation system compared with different pairings of Epiphany, Resilon, AH Plus and gutta-percha
    M Ungor
    Department of Endodontics, Faculty of Dentistry, Baskent University, Ankara, Turkey
    Int Endod J 39:643-7. 2006
    ..Irrigation was performed with 15 mL of 1.25% NaOCl between each instrument and the smear layer was removed during and after instrumentation with 5 mL of 17% EDTA...
  54. ncbi The effectiveness of different acid irrigating solutions in root canal cleaning after hand and rotary instrumentation
    Mercedes Pérez-Heredia
    Department of Dental Pathology and Therapeutics, School of Dentistry, University of Granada Spain, Campus de Cartuja, Granada, Spain
    J Endod 32:993-7. 2006
    ..A scoring system for debris and smear layer was used. Acid solutions with 2...
  55. ncbi Comparative study of the sealing ability of a polydimethylsiloxane-based root canal sealer
    Nickolaos Economides
    Department of Endodontology, Faculty of Dentistry, Aristotle University of Thessaloniki, Greece
    Braz Dent J 16:145-8. 2005
    ..polydimethylsiloxane sealer), Endion (glass-ionomer sealer) and Topseal (epoxy resin sealer), with and without smear layer removal...
  56. ncbi An ex vivo evaluation of a new root canal irrigation technique with intracanal aspiration
    Y Fukumoto
    Pulp Biology and Endodontics, Graduate School, Tokyo Medical and Dental University, 5 45 Yushima 1 chome, Bunkyo ku, Tokyo 113 8549, Japan
    Int Endod J 39:93-9. 2006
    To evaluate the effectiveness of a new root canal irrigation technique with intracanal aspiration in removing the smear layer and to assess irrigant extrusion ex vivo.
  57. ncbi Application of biologically-oriented dentin bonding principles to the use of endodontic irrigants
    Franklin Garcia-Godoy
    Biosciences Research Center, Department of Endodontics, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA
    Am J Dent 18:281-90. 2005
    To compare the removal of smear layer and the structure of the hybrid layer formed after the use of EDTA or MTAD solutions when used as a final flush.
  58. ncbi The effect of high-frequency electrical pulses on organic tissue in root canals
    M Lendini
    Private Practice, Turin, Italy
    Int Endod J 38:531-8. 2005
    To evaluate debris and smear layer scores after application of high-frequency electrical pulses produced by the Endox Endodontic System (Lysis Srl, Nova Milanese, Italy) on intact pulp tissue and organic and inorganic residues after ..
  59. ncbi Ultrastructure of intraradicular dentin after irrigation with BioPure MTAD. II. The consequence of obturation with an epoxy resin-based sealer
    Franklin R Tay
    Department of Oral Biology and Maxillofacial Pathology, School of Dentistry, Medical College of Georgia, Augusta, 30912, USA
    J Endod 32:473-7. 2006
    ..Transmission electron microscopy confirmed that the reduction in irrigation time did not compromise the smear layer removing capacity of these two irrigants when 1.3% NaOCl was employed as the initial rinse...
  60. ncbi Evaluation of ethylenediaminetetraacetic acid (EDTA) solution and gel for smear layer removal
    Sidney Ricardo Dotto
    Centro de Pesquisas Odontologicas Sao Leopoldo Mandic, Rua José Rocha Junqueira 13, CEP 13045 755 Campinas, SP, Brazil
    Aust Endod J 33:62-5. 2007
    ..The presence of a smear layer was analysed after instrumentation using scanning electron microscopy...
  61. ncbi The influence of smear layer in lateral channels filling
    Angelica Bertacci
    Endodontics Unit, Department of Oral Sciences, University of Bologna, Via San Vitale 59, 40125 Bologna, Italy
    Clin Oral Investig 11:353-9. 2007
    ..the ability of a warm gutta-percha obturation system Thermafil to fill lateral channels in presence/absence of smear layer. Forty single-rooted extracted human teeth were randomly divided into two groups for which different irrigation ..
  62. ncbi The efficacy of ultrasonic irrigation to remove artificially placed dentine debris from human root canals prepared using instruments of varying taper
    L W M van der Sluis
    Department of Cariology Endodontology Pedodontology, Academic Centre for Dentistry Amsterdam ACTA, Amsterdam, The Netherlands
    Int Endod J 38:764-8. 2005
    ..To investigate the influence of the taper of root canals on the effectiveness of ultrasonic irrigation to remove artificially placed dentine debris...
  63. ncbi Effect of EDTA with and without surfactants or ultrasonics on removal of smear layer
    Jeen Nee Lui
    Department of Restorative Dentistry, National Dental Centre, 5 Second Hospital Avenue, Singapore 168938, Republic of Singapore
    J Endod 33:472-5. 2007
    ..acid (EDTA) solution with surfactants, to 17% EDTA, with and without the use of ultrasonics, in removal of the smear layer. Seventy-five extracted teeth, randomly distributed into 5 test groups, were prepared by using ProFile rotary ..
  64. ncbi Assessment of a gel-type chelating preparation containing 1-hydroxyethylidene-1, 1-bisphosphonate
    S Girard
    Department of Preventive Dentistry, Periodontology, and Cariology, , , Switzerland
    Int Endod J 38:810-6. 2005
    ..with sodium hypochlorite, its calcium binding capacity, and its potential in preventing the formation of a smear layer when used in conjunction with rotary root canal preparation...
  65. ncbi Smear layer removal and chelated calcium ion quantification of three irrigating solutions
    Andre Augusto Franco Marques
    School of Dentistry, , Rua Pau Brasil 310, , SP, Brazil
    Braz Dent J 17:306-9. 2006
    The purpose of this study was to evaluate, by scanning electron microscopy (SEM), smear layer removal and quantify, by atomic absorption spectrophotometry, the amount of calcium ion present in the chelating solutions after their use...
  66. ncbi Real-time atomic force microscopy of root dentine during demineralization when subjected to chelating agents
    G De-Deus
    Department of Endodontics, Rio de Janeiro State University, Rio de Janeiro, Brazil
    Int Endod J 39:683-92. 2006
    ..To explore the potential of atomic force microscopy (AFM) for the examination of changes to dentine surfaces during demineralization and evaluate qualitatively the effect of EDTA, EDTAC and citric acid...
  67. ncbi Appearance of the root canal walls after preparation with NiTi rotary instruments: a comparative SEM investigation
    Carlo Prati
    Endodontics Unit, Department of Dental Sciences, University of Bologna, Alma Mater Studiorum, Via S Vitale 59, Bologna, Italy
    Clin Oral Investig 8:102-10. 2004
    ..middle and apical third, comparing its aspect with a predefined scale of four different parameters: presence of smear layer, pulpal debris, inorganic debris and surface profile...
  68. ncbi A comparison of techniques for assessment of coronal dye leakage
    Suwit Wimonchit
    Department of Restorative Dentistry, Faculty of Dentistry, Khon-Kaen University, Thailand
    J Endod 28:1-4. 2002
    ..One group was rinsed with 5.25% NaOCl (smear layer intact), whereas the other group was flushed with 17% EDTA and 5.25% NaOCl (smear layer removed)...
  69. ncbi Adhesion of a glass-ionomer root canal sealer to the root canal wall
    S Timpawat
    Department of Operative Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand
    J Endod 27:168-71. 2001
    ..specimens were divided into five groups of 10 teeth, and the groups were conditioned with one of the following smear layer removal solutions: 15% EDTA/NaOCl, 10% polyacrylic acid, 35% phosphoric acid, 6% citric acid, and 5...
  70. ncbi Time-dependent effects of EDTA on dentin structures
    Semra Calt
    Department of Endodontics, Hacettepe University, Faculty of Dentistry, Sihhiye, Ankara, Turkey
    J Endod 28:17-9. 2002
    The purpose of this study was to evaluate the effects of EDTA on smear layer removal and on the structure of dentin, after 1 and 10 min of application. Six extracted single-rooted teeth were instrumented to #60...
  71. ncbi Comparative in-vitro evaluation of three chelator pastes
    M Hulsmann
    Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Gottingen, Germany
    Int Endod J 35:668-79. 2002
    ..To compare the effect of three paste chelating agents on the root dentine of extracted teeth: Calcinase-Slide (lege artis, Dettenhausen, Germany), Glyde-File (DeTrey/Dentsply, Konstanz, Germany), RC-Prep (Premier, Norristown, USA)...
  72. ncbi A comparative study of root canal preparation using FlexMaster and HERO 642 rotary Ni-Ti instruments
    M Hulsmann
    Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Gottingen, Germany
    Int Endod J 36:358-66. 2003
    ..To compare several parameters of root canal preparation using two different rotary nickel-titanium (Ni-Ti) instruments: FlexMaster (VDW, Munich, Germany) and HERO 642 (Micro-Mega, Besançon, France)...
  73. ncbi Shear bond strength of AH-26 root canal sealer to dentine using three dentine bonding agents
    Christos Gogos
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
    J Dent 31:321-6. 2003
    ..The materials used were AH-26 sealer, two one-bottle bonding agents (Single Bond, Bond-1) and one self-etching bonding agent (Clearfill SE Bond)...
  74. ncbi Scanning electron microscopic study of the cleaning ability of chlorhexidine as a root-canal irrigant
    J C Yamashita
    School of Dentistry, Sacred Heart University, Bauru, Brazil
    Int Endod J 36:391-4. 2003
    ..CONCLUSIONS: The apical third of the root canals was not cleaned as well as the middle and coronal thirds. Cleaning by chlorhexidine and saline was inferior compared to the cleaning by sodium hypochlorite with and without EDTA...
  75. ncbi Evaluation of Glyde File Prep in combination with sodium hypochlorite as a root canal irrigant
    Simone Grandini
    Department of Restorative Dentistry, University of Siena, Italy
    J Endod 28:300-3. 2002
    ..After scanning electron microscopic evaluation at three different levels, debris, smear layer, and dentinal tubules were scored...
  76. ncbi Obturation of accessory canals after four different final irrigation regimes
    Juan Camilo Villegas
    Pulp Biology and Endodontics, Graduate School, Tokyo Medical and Dental University, Japan
    J Endod 28:534-6. 2002
    ..05). The use of sodium hypochlorite alone or in combination with EDTA in final irrigation flushes may enhance a better obturation material penetration into the accessory canals...
  77. ncbi The demineralizing effects of EDTA at different concentrations and pH
    Ahmet Serper
    Department of Endodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey
    J Endod 28:501-2. 2002
    ..0. The pH of the EDTA solutions did not display any significant alterations during the demineralization process...
  78. ncbi Evaluation of canal cleanliness and smear layer removal after the use of the Quantec-E irrigation system and syringe: a comparative scanning electron microscope study
    Jason Setlock
    University of Illinois at Chicago, Department of Endodontics, Chicago, Illinois 60612-7212. USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:614-7. 2003
    OBJECTIVE: The purpose of this study was to evaluate canal cleanliness and smear layer removal after use of the Quantec-E irrigation system and to compare the system with traditional irrigation...
  79. ncbi The removal of the smear layer using EGTA: a scanning electron microscopic study
    Deepak Viswanath
    Department of Pedodontics and Preventive Children Dentistry, ABSMIDS, Mangalore, Karnataka, India
    J Clin Pediatr Dent 28:69-74. 2003
    The smear layer associated with endodontic instrumentation is currently thought to be a thin layer that occludes the orifices of the dentinal tubules and covers the intertubular dentin of the prepared canal wall...
  80. ncbi Comparative study of root-canal preparation using Lightspeed and Quantec SC rotary NiTi instruments
    M Hulsmann
    Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Gottingen, Germany
    Int Endod J 36:748-56. 2003
    ..To compare several parameters of root-canal preparation using two different rotary nickel-titanium (NiTi) instruments: Lightspeed (Lightspeed Inc, San Antonio, TX, USA) and Quantec SC (Tycom, Irvine, USA)...
  81. ncbi Penetration of propylene glycol into dentine
    E V Cruz
    Department of Operative Dentistry and Endodontics and Oral Microbiology, Cariology Research Unit, Niigata University School of Dentistry, Niigata, Japan
    Int Endod J 35:330-6. 2002
    ..O in propylene glycol and in distilled water were introduced into root canals with and without artificial smear layer. Dye diffusion through dentinal tubules was determined spectrophotometrically...
  82. ncbi Chelating agents in root canal treatment: mode of action and indications for their use
    M Hulsmann
    Department of Operative Dentistry, Preventive Dentistry and Periodontology, University of Gottingen, Gottingen, Germany
    Int Endod J 36:810-30. 2003
    ..ethylenediaminetetraacetic acid (EDTA) was thought to chemically soften the root canal dentine and dissolve the smear layer, as well as to increase dentine permeability...
  83. ncbi Comparative analysis of root surface smear layer removal by different etching modalities or erbium:yttrium-aluminum-garnet laser irradiation. A scanning electron microscopy study
    Leticia Helena Theodoro
    Center for Lasers and Applications, Laboratory of Biophotonics Center for Lasers and Applications IPEN CNEN SP, Av Lineu Prestes, 2242 Cidade Universitária USP CEP, Sao Paulo, SP, 05508 000, Brazil
    Lasers Med Sci 25:485-91. 2010
    ..94 mum) irradiation on the removal of root surface smear layer of extracted human teeth and to compare its efficacy with that of citric acid, ethylenediamine tetra-acetic ..
  84. ncbi Comparison of bacterial reduction in straight and curved canals using erbium, chromium:yttrium-scandium-gallium-garnet laser treatment versus a traditional irrigation technique with sodium hypochlorite
    Nathan Dewsnup
    Department of Endodontics, University of Florida, Gainesville, FL 32610 0436, USA
    J Endod 36:725-8. 2010
    ..This study compared the reduction of Enterococcus faecalis in straight and curved canals using an erbium, chromium:yttrium-scandium-gallium-garnet laser and irrigation with 6.15% sodium hypochlorite (NaOCl)...
  85. ncbi Dentin permeability after toothbrushing with different toothpastes
    C Prati
    University of Bologna, School of Dentistry, Department of Emergency Dentistry, Italy
    Am J Dent 12:190-3. 1999
    To evaluate the interaction of smear layer produced during brushing and dentifrice particles.
  86. ncbi Effect of etching agent on dentinal adhesive interface in primary teeth
    R M Rontani
    Department of Pediatric Dentistry, Piracicaba School of Dentistry, University of Campinas, Av Limeira, 901, Piracicaba 13414 018 SP, Brazil
    J Clin Pediatr Dent 24:205-9. 2000
    ..The presence of an amorphous layer, which was unremoved smear layer, was noted. The group treated with 35% phosphoric acid showed a hybrid layer formation (8.15 microns)...
  87. ncbi Effects of three canal sealers on bond strength of a fiber post
    Ebru Ozsezer Demiryürek
    Department of Dentistry, Samsun, Turkey
    J Endod 36:497-501. 2010
    ..This study evaluated the effects of three different endodontic sealers on the bond strength of a fiber post cemented with adhesive resin cement...
  88. ncbi Shear bond strength of two resin cements to human root dentin using three dentin bonding agents
    C Gogos
    Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Greece
    Oper Dent 32:31-6. 2007
    ..rooted human teeth, and the specimens were treated with either 15% EDTA or 37% phosphoric acid to remove the smear layer, except in groups where the self-etching bonding agent was used...
  89. ncbi Clinical considerations of microleakage
    D H Pashley
    Department of Oral Biology Physiology, School of Dentistry, Medical College of Georgia, Augusta
    J Endod 16:70-7. 1990
    ..and the location of the dentin in a tooth, another extremely important variable is the presence or absence of a smear layer. When smear layers are created, grinding debris are forced into each tubule to form a smear plug...
  90. ncbi Changes in dentin after insertion of self-threading titanium pins with 3 methods: a scanning electron microscope pilot study
    Sanja Segović
    Department of Endodontology and Restorative Dentistry, School of Dental Medicine, University of Zagreb, Croatia
    J Prosthet Dent 87:182-8. 2002
    ..Inserting a self-threading pin can cause dentinal cracks, but it is not known whether dentin bonding agents can penetrate these cracks...
  91. ncbi 2000 Judson C. Hickey Scientific Writing Award. Effect of impression materials on hybridized dentin
    M Nahon
    School of Dentistry, The Medical College of Georgia, Augusta, Ga 30912 1260, USA
    J Prosthet Dent 85:568-74. 2001
    ..Tooth sensitivity after crown preparation is not an uncommon complication. For dentin bonding agents to be effective in preventing postoperative sensitivity, they must remain intact throughout the fixed prosthodontic procedures...
  92. ncbi Effect of lactic acid irrigant on shear bond strength of Epiphany adhesive sealer to human dentin surface
    Mohamed F Ayad
    Section of Restorative Dentistry, Prosthodontics and Endodontics, College of Dentistry, University of Tanta and King Abdulaziz University, Tanta, Egypt
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:e100-6. 2010
    ..To examine the effects of varied dilutions of lactic acid as a root canal irrigant and compare the shear bond strength of Epiphany adhesive sealer to human dentin surface with other solutions deemed to be suitable root canal irrigants...
  93. ncbi The impact of an erbium, chromium:yttrium-scandium-gallium-garnet laser with radial-firing tips on endodontic treatment
    U Schoop
    Department of Conservative Dentistry, Dental School, Medical University of Vienna, Vienna, Austria
    Lasers Med Sci 24:59-65. 2009
    ..Scanning electron microscopy showed the homogeneous removal of smear layer from the root canal walls...
  94. ncbi In vitro assessment of the effectiveness of chlorhexidine gel and calcium hydroxide paste with chlorhexidine against Enterococcus faecalis and Candida albicans
    Ertugrul Ercan
    Department of Operative Dentistry, School of Dentistry, University of Kirikkale, Kirikkale, Turkey
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e27-31. 2006
    ..The purpose of this study was to compare the effectiveness of various medicaments, including Ca(OH)2/2% chlorhexidine, 2% chlorhexidine gel, and Ca(OH)2 alone, against Enterococcus faecalis and Candid albicans in vitro...
  95. ncbi Effect of ZOE temporary restoration on resin-dentin bond strength using different adhesive strategies
    Ceci Nunes Carvalho
    Dental School, University of São Paulo USP São Paulo Brazil
    J Esthet Restor Dent 19:144-52; discussion 153. 2007
    ..Little is known about the effect of a eugenol-containing temporary restorative material on the resin-dentin bond strength of adhesive systems that partially dissolves and modifies the smear layer.
  96. ncbi Evaluation of dentin root canal permeability after instrumentation and Er:YAG laser application
    J D Pecora
    Dental School of Ribeirao Preto, University of Sao Paulo, 14040 904, Ribeirao Preto SP, Brazil
    Lasers Surg Med 26:277-81. 2000
    b>Smear layer removal with EDTA from root canal walls allows greater cleaning and disinfection of root canals...
  97. ncbi Coronal sealing ability of a new root canal filling material
    Emre Bodrumlu
    Ondokuz Mayis University, Faculty of Dentistry, Operative Dentistry and Endodontics Department, 55139 Kurupelit Samsun Turkey
    J Can Dent Assoc 73:623. 2007
    ..The purpose of this study was to evaluate the coronal sealing ability of the new endodontic obturation system...
  98. ncbi The influence of a local anesthetic containing vasoconstrictor on microtensile bond strengths of two adhesive systems to human dentin in situ
    Choltacha Harnirattisai
    Department of Operative Dentistry, Faculty of Dentistry, Mahidol University, Rajthewee, Bangkok, Thailand
    J Adhes Dent 12:11-8. 2010
    ....
  99. ncbi Evaluation of the furcation area permeability of deciduous molars treated by neodymium:yttrium-aluminum-garnet laser or adhesive
    Camila A B Guglielmi
    Department of Restorative Dentistry, School of Dentistry, University of Sao Paulo, Av Prof Lineu Prestes, 2227, Sao Paulo, SP, 005508 000, Brazil
    Lasers Med Sci 25:873-80. 2010
    ..05). The SEM analysis showed mostly dentinal tubules obliterated by smear layer in the CG; in the AG the smear layer was modified by the adhesive, and, in the LG, melted surfaces were ..
  100. ncbi Effect of an acid diet allied to sonic toothbrushing on root dentin permeability: an in vitro study
    Shelon Cristina Souza Pinto
    Department of Oral Diagnosis and Surgery, Araraquara Dental School, Sao Paulo State University, Araraquara, SP, Brazil
    Braz Dent J 21:390-5. 2010
    ..5 specimens in each: 1) phosphoric acid etching for 30 s (maximum permeability), 2) root planning to create new smear layer, 3) exposure to different acid substances for 5 min (orange, cola drink, vinegar, white wine, lemon juice), 4) ..
  101. ncbi In vitro evaluation of the effect of dietary acids and toothbrushing on human root dentin permeability
    Daniela Leal Zandim
    Department of Diagnostic and Oral Surgery, School of Dentistry at Araraquara, Sao Paulo State University, Araraquara, Sao Paulo, Brazil
    Quintessence Int 41:257-63. 2010
    ..The purpose of this in vitro study was to quantify the alterations in human root dentin permeability after exposure to dietary acids and to evaluate the effect of toothbrushing after acid application...

Research Grants31

  1. Dentin/Adhesive Interface Structure/Property Imaging
    Yong Wang; Fiscal Year: 2006
    ....
  2. Molecular/Mechanical Imaging of Dentin Bonding Substrate
    Yong Wang; Fiscal Year: 2007
    ..Results from this work will provide critical, new insight into failure mechanisms at the dentin/adhesive interface; failure that can ultimately lead to premature breakdown of the composite restoration. ..
  3. Reasons for poor durability of resin-dentin bonds
    David Pashley; Fiscal Year: 2007
    ..This comprehensive approach to improving the durability of resin-dentin bonds should ultimately save billions of dollars in health care and much human suffering. ..
  4. Radiation Therapy Impact on Structure/Mechanics of Teeth
    Mary Walker; Fiscal Year: 2007
    ..A key strength of this project is the associated feedback mechanism that relates the clinical problem to both clinical and laboratory data, the integration of scientific principles into clinical practice. ..
  5. RESIN-BASED REMINERALIZING CEMENTS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2009
    ..Completion of this research will lead to Ca- PO4 cements and composites with improved adhesion to dentin and improved strength for ART and the treatment of root caries. ..
  6. Reasons for poor durability of resin-dentin bonds
    David Pashley; Fiscal Year: 2009
    ..Their successful use in adhesive resins could potentially save billions of dollars currently spent on the replacement of tooth-colored resin composites. ..
  7. Reasons for poor durability of resin-dentin bonds
    David H Pashley; Fiscal Year: 2010
    ..Their successful use in adhesive resins could potentially save billions of dollars currently spent on the replacement of tooth-colored resin composites. ..
  8. IMPROVED PREVENTIVE/RESTORATIVE RESINS AND COMPOSITES
    SABINE DICKENS; Fiscal Year: 2006
    ..The data gathered in these experiments will serve to support a larger R01 grant application with the long-term objectives of developing improved durable materials for adhesives and adhesive composites. ..
  9. Determinants of the Durability of Resin-Dentin Bonds
    David Pashley; Fiscal Year: 2006
    ..This should provide important new insight into designing more durable resin-dentin bonds that can justify the placement of resin-based posterior composites. ..
  10. REMINERALIZING PULP-CAPPING CEMENTS & BONDING AGENTS
    SABINE DICKENS; Fiscal Year: 2003
    ..The proposed studies will also provide a valuable comparison of in vivo test results to pulp cell response in vitro. ..
  11. Understanding the mechanism of radiotherapy-induced dentition breakdown
    Yong Wang; Fiscal Year: 2010
    ..Thus, future improvements for preventing and treating post-radiation dentition breakdown depend on new knowledge of the underlying mechanism of radiation-induced damage at the tooth level. ..