Genomes and Genes
Summary: Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis.
Publications232 found, 100 shown here
- Histological analysis of rat dental pulp tissue capped with propolisArdo Sabir
Department of Conservative Dentistry, Faculty of Dentistry, Hasanuddin University, Makassar 90245, Indonesia
J Oral Sci 47:135-8. 2005..Partial dentinal bridge formation was seen in group II at week 4. Therefore, the present results suggest that direct pulp capping with propolis flavonoids in rats may delay dental pulp inflammation and stimulate reparative dentin...
- The effect of pulpotomy using a calcium-enriched mixture cement versus one-visit root canal therapy on postoperative pain relief in irreversible pulpitis: a randomized clinical trialSaeed Asgary
Iranian Center for Endodontic Research, Dental Research Center, Dental School, Shahid Beheshti Medical University, Evin, Tehran, 1983963113, Iran
Odontology 98:126-33. 2010..with a new endodontic calcium-enriched mixture cement (PCEM) in human permanent molars with irreversible pulpitis. A total of 407 selected patients were randomly allocated into the ORCT group (n = 202) or the PCEM group (n = ..
- Fate of the tissue in lateral canals and apical ramifications in response to pathologic conditions and treatment proceduresDomenico Ricucci
Private Practice, Rome, Italy
J Endod 36:1-15. 2010..This article reviews and reports on the histopathologic and histobacteriologic status of the tissue in lateral canals and apical ramifications (LC/AR) in diverse clinical conditions as well as in response to endodontic treatment...
- Herpesviruses in endodontic pathoses: association of Epstein-Barr virus with irreversible pulpitis and apical periodontitisHong Li
Department of Endodontology, Oregon Health and Science University, School of Dentistry, Portland, Oregon 97239, USA
J Endod 35:23-9. 2009Irreversible pulpitis and apical periodontitis are inflammatory diseases caused by opportunistic bacteria with possible co-infection with latent herpesviruses...
- The anti-inflammatory effects of matrix metalloproteinase-3 on irreversible pulpitis of mature erupted teethHisanori Eba
Department of Dental Regenerative Medicine, Center of Advanced Medicine for Dental and Oral Diseases, National Center for Geriatrics and Gerontology, Obu, Aichi, Japan
PLoS ONE 7:e52523. 2012..Therefore, we have further extended these studies using a canine irreversible pulpitis model to investigate the effects of MMP-3...
- Anesthetic efficacy of the supplemental X-tip intraosseous injection in patients with irreversible pulpitisJohn Nusstein
Department of Oral Biology, The Ohio State University, Columbus 43218, USA
J Endod 29:724-8. 2003..using the X-tip system in an apical location, in mandibular posterior teeth diagnosed with irreversible pulpitis when the conventional inferior alveolar nerve block failed...
- The significance of needle deflection in success of the inferior alveolar nerve block in patients with irreversible pulpitisShawn Kennedy
US Army, Fort Stewart, GA, USA
J Endod 29:630-3. 2003..administered using the computer-assisted Wand II anesthesia system, in patients diagnosed with irreversible pulpitis. Sixty-four emergency patients diagnosed with irreversible pulpitis of a mandibular posterior tooth randomly ..
- Quantitative microbiological study of human carious dentine by culture and real-time PCR: association of anaerobes with histopathological changes in chronic pulpitisF Elizabeth Martin
Institute of Dental Research, Westmead Centre for Oral Health, Westmead Hospital, P O Box 533, Wentworthville NSW 2145, Australia
J Clin Microbiol 40:1698-704. 2002..with the tissue response of the dental pulps of 65 teeth extracted from patients with advanced caries and pulpitis. Standardized homogenates of carious dentine were plated onto selective and nonselective media under anaerobic ..
- Articaine for supplemental intraosseous anesthesia in patients with irreversible pulpitisJason Bigby
Section of Endodontics, College of Dentistry, The Ohio State University, Columbus, Ohio 43218, USA
J Endod 32:1044-7. 2006..epinephrine for supplemental intraosseous injection in mandibular posterior teeth diagnosed with irreversible pulpitis. Thirty-seven emergency patients, diagnosed with irreversible pulpitis of a mandibular posterior tooth, received ..
- Anesthetic efficacy of articaine for inferior alveolar nerve blocks in patients with irreversible pulpitisElizabeth Claffey
Department of Oral Surgery, Oral Pathology, and Anesthesiology, The Ohio State University, Columbus, OH 43218, USA
J Endod 30:568-71. 2004..2% lidocaine with 1:100,000 epinephrine for inferior alveolar nerve blocks in patients experiencing irreversible pulpitis in mandibular posterior teeth...
- Modulation of astroglial glutamine synthetase activity affects nociceptive behaviour and central sensitization of medullary dorsal horn nociceptive neurons in a rat model of chronic pulpitisY Tsuboi
Faculty of Dentistry, University of Toronto, Toronto, ON, Canada
Eur J Neurosci 34:292-302. 2011..of MDH nociceptive neurons and the animal's associated behaviour that are manifested in a model of chronic pulpitis pain induced by exposure of a mandibular molar pulp...
- Articaine (4%) with epinephrine (1:100,000 or 1:200,000) in intraosseous injections in symptomatic irreversible pulpitis of mandibular molars: anesthetic efficacy and cardiovascular effectsLeandro Augusto Pinto Pereira
Department of Pharmacology, Anesthesiology, and Therapeutics, São Leopoldo Mandic Dental School, Campinas, Brazil
Oral Surg Oral Med Oral Pathol Oral Radiol 116:e85-91. 2013..The aim of this study was to compare the cardiovascular effects and the anesthetic efficacy of intraosseous injections of 4% articaine with 1:100,000 epinephrine (EPI100) or 4% articaine with 1:200,000 epinephrine (EPI200)...
- Comparison of the anesthetic efficacy between bupivacaine and lidocaine in patients with irreversible pulpitis of mandibular molarRoberta Moura Sampaio
Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
J Endod 38:594-7. 2012..5% bupivacaine with 1:200,000 epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth.
- A prospective randomized trial of different supplementary local anesthetic techniques after failure of inferior alveolar nerve block in patients with irreversible pulpitis in mandibular teethMohammad D Kanaa
Centre for Oral Health Research, Newcastle University, Newcastle upon Tyne, England
J Endod 38:421-5. 2012..or intraosseous injection (both with 2% lidocaine with epinephrine) after failed inferior alveolar nerve block (IANB) for securing pain-free treatment in patients experiencing irreversible pulpitis in mandibular permanent teeth.
- Anesthetic efficacy of four percent articaine for pulpal anesthesia by using inferior alveolar nerve block and buccal infiltration techniques in patients with irreversible pulpitis: a prospective randomized double-blind clinical trialSaravanan Poorni
Department of Conservative Dentistry and Endodontics, Ragas Dental College, Chennai, India
J Endod 37:1603-7. 2011..double-blind trial to evaluate the anesthetic efficacy of 4% articaine with 1:100,000 epinephrine in inferior alveolar nerve block (IANB) and infiltration anesthetic techniques to anesthetize mandibular molars with irreversible pulpitis.
- Putative stem cells in human dental pulp with irreversible pulpitis: an exploratory studyZhengyan Wang
Dental Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
J Endod 36:820-5. 2010..characterized, it is unknown whether stem cells also exist in clinically compromised teeth with irreversible pulpitis. Here we explored whether cells retrieved from clinically compromised dental pulp have stem cell-like properties.
- Histology of Irreversible pulpitis premolars treated with mineral trioxide aggregate pulpotomyLing Huey Chueh
Elite Dental Clinic, Taipei, Taiwan
Oper Dent 35:370-4. 2010..In this case report, a 19-year-old female patient with a second premolar with irreversible pulpitis and symptomatic apical periodontitis was treated with MTA pulpotomy...
- Anesthetic efficacy of lidocaine/meperidine for inferior alveolar nerve blocks in patients with irreversible pulpitisJason Bigby
Department of Endodontics, College of Dentistry, The Ohio State University, Columbus, Ohio, USA
J Endod 33:7-10. 2007..for inferior alveolar nerve blocks (IAN) in patients with mandibular posterior teeth experiencing irreversible pulpitis. Forty-eight emergency patients diagnosed with irreversible pulpitis of a mandibular posterior tooth randomly ..
- A real time quantitative PCR analysis and correlation of COX-1 and COX-2 enzymes in inflamed dental pulps following administration of three different NSAIDsClaudia I Holt
Department of Endodontics and Periodontics, University of Texas Dental, Branch at Houston, Houston, Texas, USA
J Endod 31:799-804. 2005..However, Vioxx and Advil significantly reduced COX-2 expression levels compared to inflamed (positive control) pulps (p < 0.05)...
- [Padma 28 in the treatment of chronic dental pulpitis: an observational case study in 49 patients]Fritz Füllemann
Private Praxis, Kronbühl, Schweiz
Forsch Komplementmed 13:28-30. 2006In the case of pulpitis the dentist has to differentiate between a reversible and therefore treatable pulpal inflammation and an irreversible damage of the pulpa, accord-ing to the clinical symptoms...
- Anesthetic effectiveness of the supplemental intraligamentary injection, administered with a computer-controlled local anesthetic delivery system, in patients with irreversible pulpitisJohn Nusstein
Department of Endodontics, The Ohio State University, Columbus, Ohio 43218, USA
J Endod 31:354-8. 2005..a computer-controlled local anesthetic delivery system, in mandibular posterior teeth diagnosed with irreversible pulpitis when the conventional inferior alveolar nerve block failed...
- Effect of combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve block in patients with symptomatic irreversible pulpitisMichael Simpson
The Ohio State University, Columbus, OH, USA
J Endod 37:593-7. 2011..study was to determine the effect of the administration of the combination of preoperative ibuprofen/acetaminophen on the success of the inferior alveolar nerve (IAN) block in patients with symptomatic irreversible pulpitis.
- Lipopolysaccharide-induced pulpitis up-regulates TRPV1 in trigeminal gangliaM K Chung
University of Maryland Baltimore School of Dentistry, Program in Neuroscience, Department of Neural and Pain Sciences, 650 W Baltimore Street, Baltimore, MD 21201, USA
J Dent Res 90:1103-7. 2011Tooth pain often accompanies pulpitis. Accumulation of lipopolysaccharides (LPS), a product of Gram-negative bacteria, is associated with painful clinical symptoms...
- Effect of sublingual triazolam on the success of inferior alveolar nerve block in patients with irreversible pulpitisMatthew Lindemann
Private Practice Limited to Endodontics, Flint, Michigan, USA
J Endod 34:1167-70. 2008..triazolam on the success of the inferior alveolar nerve (IAN) block in patients experiencing irreversible pulpitis. Fifty-eight emergency patients diagnosed with irreversible pulpitis of a mandibular posterior tooth randomly ..
- Delayed partial pulpotomy in a midroot and complicated crown-root-fractured permanent incisor with hyperplastic pulpitis: a case reportMehmet Kemal Calişkan
Department of Endodontics, Ege University, Izmir, Turkey
J Endod 36:1250-3. 2010..The occurrence of multiple injuries of the same tooth is extremely rare. This case report describes the treatment in a midroot and complicated crown-root-fractured permanent incisor that remained untreated for 4 years after the accident...
- Tissue levels of immunoreactive substance P are increased in patients with irreversible pulpitisWalter R Bowles
Division of Endodontics, University of Minnesota School of Dentistry, Minneapolis 55455, USA
J Endod 29:265-7. 2003..In this study, we tested the hypothesis that irreversible pulpitis is associated with increased activity of peptidergic neurons, as measured by increased pulpal levels of ..
- MTA pulpotomy of human permanent molars with irreversible pulpitisMohammad Jafar Eghbal
Department of Endodontics, Iranian Center for Endodontic Research, Dental Research Center, Shahid Beheshti University M C, Tehran, Iran
Aust Endod J 35:4-8. 2009The histological success of mineral trioxide aggregate (MTA) pulpotomy for treatment of irreversible pulpitis in human teeth as an alternative treatment was investigated in this study...
- The effect of preoperative acetaminophen or a combination of acetaminophen and Ibuprofen on the success of inferior alveolar nerve block for teeth with irreversible pulpitisStaci R Ianiro
Department of Endodontics, University of Alabama at Birmingham, Birmingham, Alabama, USA
J Endod 33:11-4. 2007..There were 40 patients with irreversible pulpitis randomly assigned to a drug or placebo group...
- Comparison of anesthetic efficacy of 4% articaine and 2% lidocaine for maxillary buccal infiltration in patients with irreversible pulpitisNarasimhan Srinivasan
Department of Conservative Dentistry, Tamilnadu Government Dental College and Hospital, Chennai 3, India
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:133-6. 2009..randomized, double-blind study was to compare the anesthetic efficacy of 4% articaine and 2% lidocaine (both with 1:100,000 epinephrine) for buccal infiltration in patients experiencing irreversible pulpitis in maxillary posterior teeth.
- Anesthetic efficacy of inferior alveolar nerve block plus buccal infiltration or periodontal ligament injections with articaine in patients with irreversible pulpitis in the mandibular first molarSong Fan
Department of Stomatology, The Second Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108:e89-93. 2009We compared the anesthetic efficacy of inferior alveolar nerve block (IANB) plus buccal infiltration (BI) and IANB plus periodontal ligament (PDL) articaine injections in patients with irreversible pulpitis in the mandibular first molar.
- Anesthetic efficacy of supplemental buccal and lingual infiltrations of articaine and lidocaine after an inferior alveolar nerve block in patients with irreversible pulpitisVivek Aggarwal
Department of Dental Surgery, Safdarjung Hospital, New Delhi, India
J Endod 35:925-9. 2009The success rate of inferior alveolar nerve block (IANB) decreases in patients with irreversible pulpitis. It was hypothesized that supplemental infiltration of lidocaine and articaine may improve the success rates.
- Efficacy of combining a buccal infiltration with an inferior alveolar nerve block for mandibular molars with irreversible pulpitisMasoud Parirokh
Neuroscience Research Center, Oral and Dental Research Center, Kerman University of Medical Sciences, Kerman, Iran
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:468-73. 2010The aim of this study was to assess the efficacy of inferior alveolar nerve (IAN) block combined with buccal infiltration for mandibular molars with irreversible pulpitis.
- Evaluation of the effect of locally administered amitriptyline gel as adjunct to local anesthetics in irreversible pulpitis painA A Moghadamnia
Department of Pharmacology, Babol University of Medical Sciences, Babol, Iran
Indian J Dent Res 20:3-6. 2009..This study was designed to assess the additional analgesic effects of 2% Amitriptyline local gel administration in irreversible pulpitis pain of the molars.
- Irreversible but not reversible pulpitis is associated with up-regulation of tumour necrosis factor-alpha gene expression in human pulpA B Kokkas
Department of Endodontology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece
Int Endod J 40:198-203. 2007....
- Effects of an inducible nitric oxide synthase inhibitor on experimentally induced rat pulpitisHiromi Nakano Kawanishi
Pulp Biology and Endodontics, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Eur J Oral Sci 112:332-7. 2004..of an iNOS-specific inhibitor, N-(3-(aminomethyl)benzyl)acetamidine (1400W), on experimentally induced rat pulpitis in the upper incisors of 6-wk-old male Wistar rats...
- Relationships between caries bacteria, host responses, and clinical signs and symptoms of pulpitisChin Lo Hahn
Department of Endodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298 0566, USA
J Endod 33:213-9. 2007..inflammatory responses they elicit in the dental pulp is prerequisite to our understanding of the pathogenesis of pulpitis. Recent advances in immunology and neurophysiology can now explain some of the clinical manifestations of ..
- Success of an alternative for interim management of irreversible pulpitisRoger A McDougal
Department of Endodontics, University of North Carolina at Chapel Hill School of Dentistry, USA
J Am Dent Assoc 135:1707-12. 2004Extraction and endodontic therapy are treatment options for irreversible pulpitis. Extraction often is chosen for financial reasons. The authors conducted a study to investigate an alternative interim therapy.
- Predictable management of cracked teeth with reversible pulpitisP Abbott
School of Dentistry, Oral Health Centre of WA, The University of Western Australia, Nedlands WA
Aust Dent J 54:306-15. 2009..The aims of this study were to assess symptoms and signs caused by cracks in teeth and to assess a conservative management protocol...
- Transforming growth factor-beta 1 (TGF-beta 1) expression in normal healthy pulps and in those with irreversible pulpitisA Piattelli
Dental School, University of Chieti, Chieti, Italy
Int Endod J 37:114-9. 2004To evaluate the Transforming Growth Factor-beta 1 (TGF-beta 1) expression in normal healthy pulps and in those with irreversible pulpitis.
- The prevalence of secondary dentinal lesions in cheek teeth from horses with clinical signs of pulpitis compared to controlsM B Casey
Equine Diagnostic Centre, University of Bristol, Langford House, Langford, Bristol BS40 5DU, UK
Equine Vet J 42:30-6. 2010..More information regarding the association of secondary dentinal defects with apical dental disease would improve the sensitivity of oral examination as a diagnostic aid for pulpitis.
- TRPM8 Axonal expression is decreased in painful human teeth with irreversible pulpitis and cold hyperalgesiaLisa T Alvarado
Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
J Endod 33:1167-71. 2007b>Pulpitis pain might be triggered by a cold stimulus, yet the cellular mechanisms responsible for this phenomenon are largely unknown. One possible mechanism involves the direct activation of cold-responsive thermoreceptors...
- Measurement of mechanical allodynia and local anesthetic efficacy in patients with irreversible pulpitis and acute periradicular periodontitisAsma A Khan
Department of Endodontics, University of Texas Health Science Center, San Antonio, Texas, USA
J Endod 33:796-9. 2007..Mechanical pain thresholds were measured in patients (n = 30) with irreversible pulpitis (IP) and APP and compared with their contralateral teeth...
- Pulpitis increases the proportion of atypical nodes of Ranvier in human dental pulp axons without a change in Nav1.6 sodium channel expressionS Luo
Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Neuroscience 169:1881-7. 2010..The resultant heterogeneous population of isoforms may produce unique axonal excitability properties that could contribute to spontaneous pain sensations that are common in toothache...
- A six year evaluation of cracked teeth diagnosed with reversible pulpitis: treatment and prognosisKeith V Krell
Department of Endodontics, College of Dentistry, University of Iowa, Iowa City, Iowa, USA
J Endod 33:1405-7. 2007..The purpose of this investigation was to report on the clinical outcomes of cracked teeth diagnosed with reversible pulpitis (RP)...
- The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitisMasoud Parirokh
Oral and Dental Research Center, Kerman University of Medical Sciences, Kerman, Iran
J Endod 36:1450-4. 2010Achieving pulp anesthesia with irreversible pulpitis is difficult. This study evaluated whether nonsteroidal anti-inflammatory drugs assist local anesthesia.
- A comparison of the anesthetic efficacy of articaine and lidocaine in patients with irreversible pulpitisIsabel Peixoto Tortamano
Department of Stomatology, School of Dentistry, Federal University of São Paulo USP, Sao Paulo, SP, Brazil
J Endod 35:165-8. 2009..epinephrine with that of 2% lidocaine with 1:100,000 epinephrine during pulpectomy in patients with irreversible pulpitis in mandibular posterior teeth...
- Anesthetic efficacy of the Gow-Gates injection and maxillary infiltration with articaine and lidocaine for irreversible pulpitisMichael G Sherman
Department of Endodontics, Nova Southeastern University, Fort Lauderdale, Florida 33328, USA
J Endod 34:656-9. 2008..1:100,000 epinephrine (LE) for Gow-Gates blocks and maxillary infiltrations in patients experiencing irreversible pulpitis in mandibular and maxillary posterior teeth...
- Articaine for supplemental buccal mandibular infiltration anesthesia in patients with irreversible pulpitis when the inferior alveolar nerve block failsRachel Matthews
Division of Endodontics, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA
J Endod 35:343-6. 2009..a cartridge of 4% articaine with 1:100,000 epinephrine in mandibular posterior teeth diagnosed with irreversible pulpitis when the conventional inferior alveolar nerve (IAN) block failed...
- Pattern-recognition receptors in pulp defenseM J Staquet
Odontoblastes et Régénération des Tissus Dentaires, Institut de Génomique Fonctionnelle de Lyon, Universite de Lyon, CNRS, INRA, Ecole Normale Superieure de Lyon, France
Adv Dent Res 23:296-301. 2011....
- The incidence of mechanical allodynia in patients with irreversible pulpitisChristopher B Owatz
Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
J Endod 33:552-6. 2007The mechanisms of odontogenic pain are complex and incompletely understood. Cases of irreversible pulpitis are thought to represent a localized inflammatory response to bacterial challenge in dental pulp tissue...
- Innate immune responses of the dental pulp to cariesChin Lo Hahn
Department of Endodontics, School of Dentistry, Virginia Commonwealth University, 520 North 12th Street, Richmond, Virginia 3298 0566, USA
J Endod 33:643-51. 2007..Summaries of innate immune cells as well as their cytokines and chemokines in healthy and reversible pulpitis tissues are presented.
- Recent advances and future directives in pulp biologyJianing He
Department of Endodontics, Baylor College of Dentistry, Dallas, TX, USA
Pract Proced Aesthet Dent 18:49-50, 52. 2006
- Response of human pulps capped with different self-etch adhesive systemsM L R Accorinte
Department of Dental Material, School of Dentistry, University of Brás Cubas, Sao Paulo, SP, Brazil
Clin Oral Investig 12:119-27. 2008..Calcium hydroxide should be used as the material of choice for pulp capping, and the use of two-step self-etch adhesives for human pulp capping is contraindicated...
- Histological, ultrastructural and quantitative investigations on the response of healthy human pulps to experimental capping with mineral trioxide aggregate: a randomized controlled trialP N R Nair
Institute of Oral Biology, Section of Oral Structures and Development, Centre of Dental and Oral Medicine, University of Zurich, Zurich, Switzerland
Int Endod J 41:128-50. 2008..To investigate the pulpal response to direct pulp capping in healthy human teeth with mineral trioxide aggregate (MTA) as against calcium hydroxide cement (Dycal) as control...
- Clinical and histological evaluation of white ProRoot MTA in direct pulp cappingClaudio E Iwamoto
Department of Advanced Education in General Dentistry, Baltimore College of Dental Surgery, University of Maryland, USA
Am J Dent 19:85-90. 2006..To evaluate the clinical, radiographical and histological findings in human third molars in which mechanical pulp exposures were capped with white ProRoot mineral trioxide aggregate (WMTA)...
- Immunocytochemical investigation of immune cells within human primary and permanent tooth pulpH D Rodd
Department of Oral Health and Development, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield S10 2TA, UK
Int J Paediatr Dent 16:2-9. 2006..The aim of this study was to determine whether there are any differences in the number and distribution of immune cells within human primary and permanent tooth pulp, both in health and disease...
- Mineral trioxide aggregate pulpotomies: a case series outcomes assessmentDavid E Witherspoon
North Texas Endodontic Associates, Plano 75023, USA
J Am Dent Assoc 137:610-8. 2006..The authors describe the clinical and radiographic outcome of a series of cases involving the use of MTA in pulpotomy procedures...
- Long-term follow-up of composite resin restorations with self-etching adhesivesMasako Unemori
Department of Endodontology and Operative Dentistry, Faculty of Dental Science, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
J Dent 35:535-40. 2007..To test the hypothesis, derived from a previous short-term (7-day) assessment, that the absence of conventional pulp protection is not responsible for long-term pulp complications of composite resin restorations with self-etching adhesives...
- Immunohistochemical localization of LIM mineralization protein 1 in pulp-dentin complex of human teeth with normal and pathologic conditionsXiaoying Wang
Key Laboratory of Oral Biomedical Engineering of Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China
J Endod 34:143-7. 2008..by immunohistochemistry in all of the samples including 12 healthy teeth, 10 teeth with caries, 12 teeth with pulpitis, and 4 teeth with pulp calcification...
- Use of the cold test as a measure of pulpal anesthesia during endodontic therapy: a randomized, blinded, placebo-controlled clinical trialGrace W Hsiao-Wu
Division of Endodontics, Harvard School of Dental Medicine, 188 Longwood Avenue, Boston, MA 02115, USA
J Endod 33:406-10. 2007..20 (p = .01). Subjects who achieved a negative response to the cold test were approximately 80% less likely to experience pain during RCT compared to subjects with soft tissue signs of anesthesia alone...
- Histologic evaluation of direct pulp capping with a self-etching adhesive and calcium hydroxide in beaglesYu Lu
Endodontic Department, West China College of Stomatology, Sichuan University, Chengdu, Sichuan, China
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 102:e78-84. 2006..To evaluate the pulpal response of beagles following direct pulp capping with Clearfil SE Bond (SB), a self-etching adhesive...
- The expression and role of stromal cell-derived factor-1alpha-CXCR4 axis in human dental pulpLong Jiang
Department of General Dentistry, Ninth People s Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai Research Institute of Stomatology, Shanghai, China
J Endod 34:939-44. 2008..Taken together, these results imply that the SDF-1alpha-CXCR4 axis may play a role in the recruitment of CXCR4-positive DPCs toward the damaged sites...
- Pulpal response to a newly developed MMA based resin cement for bonding tooth-colored indirect restorationsYuichi Seki
Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Japan
Am J Dent 19:297-302. 2006....
- Equivalency study of histological responses to complete or partial pulpotomies in inflamed baboon immature first permanent molarsP Cleaton-Jones
University of the Witwatersrand, Dental Research Institute, Johannesburg, South Africa
SADJ 62:062-5. 2007..Clinical studies in humans suggest that this may also be an acceptable technique for carious exposed pulps in molar teeth, but objective histological evidence to support this perception is lacking...
- Electronic root canal length measurement before and after experimentally induced pulpitis and apical periodontitis in dogsMaja Kovacevic
Department of Dental Pathology, Medical Faculty, Brace Branchetta 20, Rijeka, 51000, Croatia
Med Biol Eng Comput 44:695-701. 2006..b>Pulpitis and apical periodontitis were induced by pulp exposure and contamination by the oral flora in the premolar teeth ..
- Clinical management and subsequent healing of teeth with horizontal root fracturesMarco Aurélio Versiani
Department of Endodontics, Brazilian Association of Dentistry, Uberlandia, Minas Gerais, Brazil
Dent Traumatol 24:136-9. 2008..In case 1, the pulp tissue was vital and no treatment was necessary. In case 2, a root canal treatment of the cervical fragment was necessary and in case 3, pulpal necrosis was verified and an apical surgery was performed...
- Histologic evaluation of pulpotomy performed with ethyl-cyanoacrylate and calcium hydroxideDiana Santana de Albuquerque
Department of Endodontics, School of Dentistry, Univesity of Pernambuco
Braz Oral Res 20:226-30. 2006....
- Update on the adaptive immune responses of the dental pulpChin Lo Hahn
Department of Endodontics, School of Dentistry, Virginia Commonwealth University, 520 North 12th Street, Richmond, Virginia 23298 0566, USA
J Endod 33:773-81. 2007..The immunopathology of abscess formation and the mechanisms for painless pulpitis are also discussed.
- The incidence of pulp healing defects with direct capping materialsPeter E Murray
Department of Endodontics, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL 33328, USA
Am J Dent 19:171-7. 2006....
- A clinical classification of the status of the pulp and the root canal systemP V Abbott
School of Dentistry, The University of Western Australia, Nedlands
Aust Dent J 52:S17-31. 2007..With a comprehensive knowledge of the pathophysiology of pain and inflammation in the pulp tissues, clinicians may accomplish this task with confidence...
- Comparison of human pulp response to total-etch and self-etch bonding agentsSeema Nayyar
Department of Operative Dentistry and Endodontics, Government Dental College, PGIMS, Rohtak, Haryana, India
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e45-52. 2007....
- Effects of hemostatic agents on the histomorphologic response of human dental pulp capped with calcium hydroxideMaria de Lourdes Rodrigues Accorinte
Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
Quintessence Int 38:843-52. 2007..To evaluate the response of human pulps capped with a calcium hydroxide [Ca(OH)2] cement after bleeding control with 2 hemostatic agents...
- Regenerative potential of dental pulpMartin Trope
Department of Endodontics, University of North Carolina, School of Dentistry, Chapel Hill, NC, USA
Pediatr Dent 30:206-10. 2008..This article explores our knowledge in this regard and the future potential of saving or even regenerating the pulp as a routine dental procedure...
- Effect of methotrexate-induced neutropenia on pulpal inflammation in ratsKoki Nakamura
Department of Endodontics, School of Dentistry, Aichi Gakuin University, Nagoya, Japan
J Endod 28:287-90. 2002..Immunohistochemically, the neutropenia resulted in inhibition of the infiltration by neutrophils. These results suggest that the neutrophil plays an important role in the defense against bacteria in pulpal tissue...
- Influence of age on the behavior of dental pulp of dog teeth after capping with an adhesive system or calcium hydroxideSandra R Mestrener
Department of Operative Dentistry, School of Dentistry, the São Paulo State University, UNESP, Sao Paulo, Brazil
Dent Traumatol 19:255-61. 2003..In conclusion, the chronological age of the pulp influenced the comparative results only for the adhesive system (P = 0.1), and the total results were better with calcium hydroxide than with the All Bond 2 system (P = 0.01)...
- Direct capping of human pulps with a dentin bonding system or with calcium hydroxide cementPreben Hörsted-Bindslev
Department of Dental Pathology, Operative Dentistry and Endodontics, Royal Dental College, Faculty of Health Sciences, University of Aarhus, Denmark
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:591-600. 2003..To study human pulp reactions to direct cappings with a dentin adhesive compared with a calcium hydroxide cement, especially with respect to formation of hard tissue in the exposure site...
- Local application of IGF1 on dental pulp mechanically exposed; in vivo study on rabbitM Haddad
Department of Oral Pathology, St Joseph University, Faculty of Dental Medicine, Beirut, Lebanon
Bull Group Int Rech Sci Stomatol Odontol 45:12-7. 2003..The results were conclusive in indicating the IGF1 as an efficient dental pulp capping product...
- Histological and scanning electron microscopy assessment of various vital pulp-therapy materialsMercedes S Dominguez
Department of Restorative Sciences, Graduate Endodontics, Baylor College of Dentistry, Dallas TX 75246, USA
J Endod 29:324-33. 2003..357) or 150 days (p = 0.198). Moreover, histologically mineral trioxide aggregate was a considerably better material than calcium hydroxide or acid-etched dentin bonding in maintaining the integrity of the pulp...
- Comparison of pulp responses to resin compositesP E Murray
College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA
Oper Dent 28:242-50. 2003..These observations suggest that adhesive systems provide acceptable biocompatibility, however, there is strong potential for improvement...
- Pulpal responses to bacterial contamination following dentin bridging beneath hard-setting calcium hydroxide and self-etching adhesive resin systemYuichi Kitasako
Cariology and Operative Dentistry, Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Dent Traumatol 24:201-6. 2008..05). Bonding agent is supposed to seal the exposure site, and the remaining bonding agent on the cavities was effective as the barrier in the dentin bridges after bacterial challenges...
- Preserving the vital pulp in operative dentistry: 2. Guidelines for successful restoration of unexposed dentinal lesionsPeter E Murray
School of Dentistry, University of Birmingham
Dent Update 29:127-34. 2002..Odontoblast survival, pulp inflammation, and tertiary dentine area are used as measures of pulp injury and repair...
- Matrix metalloproteinase-8 (MMP-8) in pulpal and periapical inflammation and periapical root-canal exudatesJ Wahlgren
Faculty of Medicine and Biomedicum, Oral Pathology Unit Laboratory Diagnostics, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
Int Endod J 35:897-904. 2002..To study the presence, levels and molecular forms of matrix metalloproteinase (MMP) -8 (collage-nase-2) in pulpal and periapical inflammation, and the changes in MMP-8 levels in root-canal exudates during root-canal treatment...
- Comparison of pulp responses following restoration of exposed and non-exposed cavitiesP E Murray
Oral Biology, Indiana University School of Dentistry, Room 271, 1121 West Michigan Street, Indianapolis, IN 46202 5186, USA
J Dent 30:213-22. 2002....
- Pulpal response to different pulp capping methods after pulp exposure by air abrasionLina Maria Cardenas-Duque
Department of Pediatric Dentistry, Nagasaki University, School of Dentistry, Japan
J Clin Pediatr Dent 26:269-73. 2002..However, the formation is delayed especially when Liner Bond II is used as capping agent...
- The mechanism of pulpal wound healingLeo Tjäderhane
Department of Endodontics, Faculty of Dentistry, University of Toronto, 124 Edward Street, Toronto, Ontario, M5G 1G6, Canada
Aust Endod J 28:68-74. 2002..In this review, some of the aspects considered to be important in pulpal wound healing are discussed...
- Regenerative potential of dental pulpMartin Trope
J Endod 34:S13-7. 2008..This article explores our knowledge in this regard and the future potential of saving or even regenerating the pulp as a routine dental procedure...
- Histomorphometric analysis of dentinal bridge formation and pulpal inflammationYuichi Kitasako
Department of Restorative Sciences, Graduate School, Tokyo Medical and Dental University, Japan
Quintessence Int 33:600-8. 2002..The importance and effects of individual pulp capping variables are not well understood; consequently histomorphometric analysis was used to analyze these variables...
- Pulpal responses to caries and dental repairA J Smith
Oral Biology School of Dentistry, University of Birmingham, UK
Caries Res 36:223-32. 2002..This review examines the interplay between these events and the opportunities for tissue regeneration following caries...
- Response of human pulps following acid conditioning and application of a bonding agent in deep cavitiesCarlos Alberto de Souza Costa
Department of Physiology and Pathology, University of Sao Paulo State Unesp, Araraquara School of Dentistry, Rua Humaita 1680, CEP 14801 903, Araraquara, Sao Paulo, Brazil
Dent Mater 18:543-51. 2002..The aim of this in vivo study was to evaluate the human dental pulp response when a one-bottle adhesive system was applied on etched or unetched deep dentine...
- Histopathologic study on pulp response to single-bottle and self-etching adhesive systemsVicente O Medina
Department of Clinical Dental Health Sciences, College of Dentistry, University of the Philippines Manila
Oper Dent 27:330-42. 2002..However, calcium hydroxide capping resulted in a higher incidence and faster rate of reparative dentin formation...
- Pulpal response to a fluoride-releasing all-in-one resin bonding systemHidekazu Sonoda
Tokyo Medical and Dental University, Graduate School, Department of Restorative Sciences, Cariology and Operative Dentistry, Japan
Oper Dent 27:271-7. 2002..The pulpal response of the Reactmer group was minimally different from that of the control group. Consequently, the Reactmer system was determined as being biologically compatible with vital pulps...
- Prostaglandin E2 and treatment outcome in pulp therapy of primary molars with carious exposuresP J Waterhouse
The Department of Child Dental Health, The Dental School, University of Newcastle upon Tyne, UK
Int J Paediatr Dent 12:116-23. 2002Prostaglandin E2 (PGE2) has been suggested as an indicator of irreversible pulpitis in permanent teeth . There is scant information on the role of chemical mediators in primary molar pulp inflammation...
- Response of human pulp capped with a bonding agent after bleeding control with hemostatic agentsMaria de Lourdes Rodrigues Accorinte
Department of Dental Materials, School of Dentistry, University of Sao Paulo, Sao Paulo, SP, Brazil
Oper Dent 30:147-55. 2005..This study evaluated the response of human pulps capped with a bonding agent after bleeding control with different hemostatic agents...
- Modulation of dental inflammation by the sympathetic nervous systemS R Haug
Department of Biomedicine, Section for Physiology, Faculty of Medicine, University of Bergen, Jonas Lies vei 91, N 5009, Bergen, Norway
J Dent Res 85:488-95. 2006..In conclusion, this article presents evidence in support of interactions between the sympathetic nervous system and dental inflammation...
- Analysis of pulpal reactions to restorative procedures, materials, pulp capping, and future therapiesPeter E Murray
Department of Oral Biology, Indiana University School of Dentistry, 1121 West Michigan Street, Indianapolis, IN 46202 5186, USA
Crit Rev Oral Biol Med 13:509-20. 2002..However, until these therapies can be introduced clinically, the avoidance of post-operative complications with conventional therapies requires attention to numerous aspects of treatment highlighted in this review...
- Adverse effects of human pulps after direct pulp capping with the different components from a total-etch, three-step adhesive systemMaria de Lourdes Rodrigues Accorinte
Department of Dental Materials, School of Dentistry, University of Sao Paulo, SP, Brazil
Dent Mater 21:599-607. 2005..The objective was to evaluate the response of human pulps capped with different components from a total-etch three-step adhesive system...
- Pulp tissue reactions to a dentin bonding agent as a direct capping agentRustem Kemal Subay
Department of Endodontics, School of Dentistry, Istanbul University, Istanbul, Turkey
J Endod 31:201-4. 2005..Direct capping with Dycal with subsequent sealing with SMPP may show favorable results in pulp tissue. SMPP may cause inflammatory changes when applied directly to exposed pulp tissue...
- Pulpal responses following direct pulp capping of healthy dog teeth with dentine adhesive systemsE Koliniotou-Koumpia
Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
J Dent 33:639-47. 2005..The aim of the present study was to evaluate the pulpal responses following direct pulp capping of mechanically exposed teeth with new dentine adhesive systems, in the preclinical model of dog teeth...
- Pulp-dentin biology in restorative dentistry. Part 4: Dental caries--characteristics of lesions and pulpal reactionsL Bjørndal
Department of Cariology and Endodontics, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
Quintessence Int 32:717-36. 2001..Optimal assessment of the prevailing clinical conditions can only be made on the basis of thorough knowledge of the biology of the pulp-dentin organ...
- Pulp-dentin biology in restorative dentistry. Part 7: The exposed pulpIvar A Mjor
Department of Operative Dentistry, University of Florida, College of Dentistry, PO Box 100415, Gainesville, Florida 32610, USA
Quintessence Int 33:113-35. 2002..If an exposure is expected through a caries lesion, stepwise excavation of the carious dentin should be considered to allow healing of the dentin and pulp prior to the final excavation of the carious dentin...
- Saving pulps--a biological basis. An overviewPeter E Murray
School of Dentistry, University of Birmingham, UK
Prim Dent Care 9:21-6. 2002..The purpose of this paper is to determine the importance of cavity preparation and restoration variables, by ranking them according to their effect on pulp injury (odontoblast survival) and pulp repair (reactionary dentine secretion)...
- Mapping Orofacial Nociceptive Pathways and Alterations Due to InflammationJOSHUA EMRICK; Fiscal Year: 2013..For example, inflammation may arise in the dental pulp (pulpitis), connective tissues supporting the dentition (gingivitis and periodontitis), muscles involved in mastication (..
- Dental Biologics for Underserved PopulationsSUSAN FU; Fiscal Year: 2010..When caries or trauma involves dental pulp, endodontic therapies are indicated. In irreversible pulpitis, the dentist or endodontist extirpates dental pulp, and obturates the instrumented root canal with bioinert ..
- Anatomy and Function of TRPM8 and TRPA1 in Nociceptors of Dental PulpJENNIFER LYNN GIBBS; Fiscal Year: 2013..One of the primary mechanisms contributing to odontalgia is inflammation of the dental pulp, or pulpitis. Cold hypersensitivity is one of the hallmarks of pulpitis...
- Mechanisms and Treatment of Dental PainMichael S Gold; Fiscal Year: 2013..have been proposed, none are able to account for the nature and extent of LA failure observed in the presence of pulpitis. In the present application, we propose to test a novel hypothesis concerning the basis of LA failure in the ..
- FACIAL BEHAVIOR RELATED TO ACUTE DENTAL PAINLinda LeResche; Fiscal Year: 1993..of pain and emotion in these TMD patients with those of a) normal, pain-free controls, b) patients with acute pulpitis pain, and c) patients with initial episode and recurrent depression. 3...
- BioPulp: Bioengineeering approaches for dental pulp regenerationSUSAN FU; Fiscal Year: 2009..When caries or trauma involves dental pulp, endodontic therapies are indicated. In irreversible pulpitis, the dentist or endodontist extirpates dental pulp, and obturates the instrumented root canal with bioinert ..
- Sodium Channel Expression in Human TeethMichael Henry; Fiscal Year: 2009..Normal wisdom teeth and diseased teeth with a diagnosis of irreversible pulpitis and known pain levels are commonly extracted, providing an ample supply of tissues for analysis...
- DISTRIBUTION OF LYMPHATICS IN THE DENTAL PULPMark Bishop; Fiscal Year: 1990..In addition it may provide insight into the remarkably variable symptoms and progress of pulpitis. Looking further ahead the retrograde perfusion method could be applied to scanning and transmission electron ..
- Prevention and Treatment of Oral Biofilms and Related Oral Disease by Soluble ChiSHENDA BAKER; Fiscal Year: 2009..to prevent and treat dental disease encompassing broad treatment applications including caries, periodontitis and pulpitis. Our novel agents interfere with microbial colonization and growth and are the basis of this proposal...
- Biomimetics for Dentin RegenerationR Rutherford; Fiscal Year: 2003..These experiments will employ our published model of reversible pulpitis induced in adult ferret teeth...
- CONTROLLED-RELEASE SEALANT TO PREVENT SECONDARY CARIESKenneth Anusavice; Fiscal Year: 2004..mutans, site specific levels of S. mutans at the margins of amalgam and composite restorations, and the width of marginal crevices adjacent to amalgam and composite restorations). ..
- International Caries Detection and Assessement SystemAmid Ismail; Fiscal Year: 2005..Finding of the workshop will be used in a second workshop, to be organized by Dr. George Stookey, which will focus on the design of caries clinical trials and new diagnostic technology. ..
- Microbiology/Immunology of Periodontal Disease in T1DMPaul Moore; Fiscal Year: 2002..An integrated multidisciplinary effort provides significant data collection capabilities essential for understanding the complex multifactorial etiology of periodontal disease in Type 1 diabetes. ..
- ORAL HEALTH OF OLDER TYPE 1 DIABETIC PATIENTSPaul Moore; Fiscal Year: 2003..This overall plan will permit us to understand the etiology of these complications and to define specific subpopulations and risk factors appropriate for future prospective oral health prevention and intervention trials. ..
- Oral Streptococci, Cytokines, PAF-r in EC CoagulationChin Lo Hahn; Fiscal Year: 2003..We also hope to provide an insight regarding streptococcal invasion into EC and offer an alternative model for the initial formation of vegetation. ..
- Michigan Oral Cancer Prevention NetworkAmid Ismail; Fiscal Year: 2003..By the end of the 3rd year, or earlier, the MOPCN would be ready to plan and implement community-based intervention studies...
- RESIN-BASED REMINERALIZING CEMENTS AND COMPOSITESSABINE DICKENS; Fiscal Year: 2009..Completion of this research will lead to Ca- PO4 cements and composites with improved adhesion to dentin and improved strength for ART and the treatment of root caries. ..
- Individual Differences in Pain Modulation as Predictors of Post-Surgical PainRobert Edwards; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Cytokine Regulation of Periradicular Pain in HumansAsma Khan; Fiscal Year: 2007..Dr Kenneth Kornman of IL Genetics will serve as a consultant on this project and will oversee the genotyping and genetic analysis. Statistical consultation will be provided by Dr. Brad Pollock. ..
- Planning Grant for Xylitol Trial in Caries-Active AdultsJames Bader; Fiscal Year: 2005....
- IMPROVED PREVENTIVE/RESTORATIVE RESINS AND COMPOSITESSABINE DICKENS; Fiscal Year: 2006..The data gathered in these experiments will serve to support a larger R01 grant application with the long-term objectives of developing improved durable materials for adhesives and adhesive composites. [unreadable] [unreadable]..
- Catastrophizing and Pain in Rheumatoid ArthritisRobert Edwards; Fiscal Year: 2008..abstract_text> ..
- Osteopontin and Molecular Mechanisms of Bone MetastasisSusan Rittling; Fiscal Year: 2006..Together, these experiments will provide important data to establish the mechanism of bone metastasis by a novel cell line and define the role of host OPN and TGF-beta as potential therapeutic targets. ..