salivary gland diseases

..Using sialendoscopes, intraductal pathology can made visible to the surgeon, aiding in diagnosis and adequate treatment...

To provide a description of surface electromyography (sEMG) of spontaneous saliva swallowing (SSS) and monitoring of swallow rate in patients with salivary gland diseases.

..Histopathologically, the mucoceles were of the extravasation type and trauma might be the most frequent etiological factor. This type of mucocele was the second most frequent one and should not be considered rare...

..These results suggest that estrogen deficiency exerts a crucial influence on autoantigen cleavage, and may cause, in part, autoimmune exocrinopathy in postmenopausal women...

..However, the extensive overlap between xerostomic patients and normal controls for all the quantitative indices calculated imposes a severe limitation on their discriminatory power...

..Three new cases of SPCA involving minor glands are added to 1 existing case in the literature to raise awareness of the lesion and to reduce the likelihood of misdiagnosis...

..We evaluate the preoperative apparent diffusion coefficient (ADC) maps of benign and malignant salivary gland tumors...

..This study was undertaken to investigate peroral balloon angioplasty of salivary-duct strictures (sialodochoplasty) in chronic sialadenitis, analysing the technique, results and limitations...

..The lymphocytes were positive for CD8, but consistently negative for CD4. CONCLUSIONS: A role of Epstein-Barr virus (EBV) and HIV, but not CMV, in the pathogenesis of DILS, is suggested by our immunohistochemical findings...

..Reduction of thyosulfide index in the blood plasma of these patients was determined. Use of antioxidant remedy in complex treatment of syaloadenopatya and syalosis was substanciated in this paper...

..After a short anatomical and semiological recall, we describe the pathologies according to their possible salivary demonstrations, and we propose in a table a useful memorandum in daily practice...

..The imaging features of different tumour types and their differential diagnoses are also discussed. Finally, staging classification and treatment options are presented...

..While aneuploidy represents a distinct indicator of malignancy SPF values are of minor relevance for dignity assessment in salivary gland tumours...

..In children the main differential diagnosis of salivary gland pathologies are addressed. In many diseases sonography is the first-line imaging modality in assessment of salivary glands...

..Biopsy is superior and the gold standard for diagnosis and cannot be replaced by MR imaging, however...

..Salivary gland function was more frequently diminished than expected in GERD. We concluded that the presence of impaired salivary gland function was considered to be one of risk factors for developing GERD symptoms...

..This intra-LEL vasculature seems to support regeneration and proliferation of salivary epithelial remnant cells...

..an ultra-fast sequence for MR sialography requiring no post-processing and to compare the acquisition technique regarding the effect of oral stimulation with a parallel acquisition technique in patients with salivary gland diseases.

..The aim of this study was to investigate the efficacy of FNAC of salivary gland lesions and to decide whether the radiologist could perform it or not...

In head and neck district, major salivary gland diseases seem to have a considerable epidemiological and clinical impact, especially in obstructive disease...

..Probably there is secretory inactivity in ferret parotid and this fosters the formation and accumulation of microliths containing calcium and disintegrated secretory material...

..Based on these results, we are developing a clinical trial to test if the hAQP1 cDNA transfer strategy will be clinically effective in restoring salivary flow in patients with IR-induced parotid hypofunction...

..Sarcoidosis also may manifest in the oral and maxillofacial region...

..CONCLUSION: This study suggests a direct association of E-cadherin expression with neoplastic histologic phenotype, which is lost in the more undifferentiated and invasive epithelial salivary gland tumours...

..Host Disease (cGVHD) in oral mucosa and minor salivary glands of 25 patients, as well as to evaluate the immunophenotype of the inflammatory cells...

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..g., inhibition of oral candidosis by protease inhibitors). This workshop considered the current evidence and proposed pertinent research questions...

..To study temporomandibular joint (TMJ) involvement, salivary gland dysfunction and oral mucosal lesions in rheumatoid arthritis (RA), and to investigate the relationship to general disease activity...

..The purpose of this case-control study was to determine whether semi-quantitative indices derived from salivary time-activity curves (TACs) are useful in the diagnosis and management of xerostomia...

..The present work provides an overview of most of the non neoplastic disorders of the salivary glands, in which the general presentation, pathology, and treatments are discussed...

..Possible future applications abound, and further investigation in this field is expected...

..1 mm, a working channel of 0.4 mm, and a separate channel for irrigation has been developed and we examined its clinical value...

..The following study points out the spatial relation of the salivary glands to the floor of the mouth and the clinical significance, and some factors referred to the development of herniations are discussed...

..Salivary gland cysts have well-defined margins, anechoic contents, posterior acoustic enhancement, and no internal blood flow. However, US appearances of some diseases may overlap, thus producing diagnostic pitfalls...

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..To determine the spectrum of disease, diagnostic accuracy and adequacy of fine needle aspirates (FNA) in human immunodeficiency virus (HIV) positive children who present with mass lesions...

..The article concerns peculiarly several clinical and therapeutic consequences of non-dontogenic orofacial infections...

..The aim of the study was to investigate the feasibility and effectiveness of botulinum toxin therapy in salivary secretory disorders...

..These cell lines provide a useful system for studying the role of tat in the immunopathogenesis of HIV-associated salivary gland disease...

..However, there are numerous minor salivary glands located in the mucosa of the head and neck which have the same predilection to the same diseases that affect the major glands but to a lesser frequency...

..The salivary glands are regularly swollen without pain; a hypofunction in the salivary secretory process may develop resulting in dry mouth feelings. In this paper these aspects will be reviewed and illustrated with patient cases...

..This article addresses differential diagnoses according to the predominant cytologic presentation with attention to the cell type and size, nature of the cytoplasm, and the smear background...

..Mucous cysts in the submandibular region--so-called 'plunging' ranula--are relatively uncommon. We report a case of a plunging ranula that complicated excision of an intraductal sialolith of the submandibular gland...

..The results establish the atrophic effect of inclusion of the chorda tympani in ductal ligation and indicate the caution that should be exercised in the extrapolation of the rodent model to the human condition...

..Association of hBD-1 with salivary mucin may facilitate peptide distribution and adherence to oral surfaces and aid its function within the oral cavity...

..Sialoendoscopy is a simple efficient mode of treatment for major salivary gland sialoliths and strictures...

..This study investigated the accuracy of FNA cytology of salivary gland lesions by correlation between histology and cytology...

..First, the possibility of salivary gland regeneration and tissue engineering is discussed with reference to stem cells, growth factors and scaffold materials. Second, the current status of gene transfer to salivary glands is discussed...

..These metal ions, which seem to be associated with secretion granules, are not necessarily contained within the granules as previously suggested, but rather are probably located at sites more proximal to the DNA...

..This study was undertaken to determine whether Tc-99m pertechnetate salivary gland scintigraphy may be used for objective assessment of salivary gland function in patients with thyroid cancer treated with I-131...

BACKGROUND AND PURPOSE: MR sialography has become an alternative imaging technique for ductal salivary gland diseases. We compared the diagnostic accuracies of MR sialography and digital subtraction sialography in patients with ..

..To assess the yield of US in the study of salivary glands and other organs involved in post-pubertal mumps...

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..CONCLUSION: Salivary gland diseases are rare in childhood and adolescence. Their pattern of incidence differs very much from that of adults...

..The aim of our study was to evaluate HEX A and HEX B activity in healthy and PA human salivary glands using colorimetric and isoelectrofocusing methods...

..The WHO classification of salivary gland diseases considers 3 oncocytic lesions: oncocytosis, oncocytoma and oncocytic carcinoma...

..sialadenitis from a personal perspective based on 15 years of clinical practice limited mainly to salivary gland diseases. Disorders of the salivary glands are uncommon...

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..documented and generally accepted that enlargement of parotid salivary glands, as part of HIV-related salivary gland diseases (HIV-SGD), may be the initial symptoms/manifestations of the HIV infection...

..However, in many salivary gland diseases, saliva-producing acinar cells are destroyed, resulting in dry mouth and secondary health conditions...

b>Salivary gland diseases should be handled with a high index of suspicion. Although an inference could be drawn it is not clear from this study if primary head and neck cancers (HNCs) have a significant association with HIV/AIDS.

..Normally, the duct network of the submandibular and parotid glands is not visible during US assessment. In obstructive sialadenitis of the parotid and submandibular glands, localization of the obstacle is often difficult...

..Predisposing factors for the ductally ascending infection, are dehydration, xerogenic drugs and salivary gland diseases associated with ductal obstructions or reduced saliva secretion...

..To describe oral diseases diagnosed in an urban referral centre in Kenya in terms of age, gender and anatomical distribution and to compare this with reports in the literature...

..In 43 patients with obstructive salivary gland diseases ultrasound examination of the parotid and submandibular glands was carried out before and after oral ..

Tumors of salivary glands in children are rare. Basically all types of salivary gland diseases during the period of childhood are described...

The ultrasonic diagnosis of salivary gland diseases can give a more accurate information than clinical data alone. In diagnosis of the parotid gland diseases, it is necessary to differentiate clearly tumors from other diseases...

Surgical management of salivary gland diseases has always been challenging because it carries a considerable risk of nerve damage...

..Furthermore, endoscopy is of high value for the diagnosis and treatment of other salivary gland diseases in which there are pathological changes of the ductal system...

..Saliva has been used to detect caries risk, periodontitis, oral cancer, breast cancer, salivary gland diseases, and systemic disorders such as hepatitis, HIV and HCV...

..The use of ultrasound can confirm a diagnosis that has been suggested by case history and findings. Evidence of a mass is an indication for fine-needle aspiration. This does not eliminate the need for histological follow-up...

..We report on 52 juvenile and adolescent patients with benign and malignant tumors of the salivary glands. Controlled follow-up was carried out to examine outcome and side effects of therapy...

..which adds significant new dimensions to the surgeon's armamentarium for management of inflammatory salivary gland diseases. Because of the rapid development in minimally invasive surgical techniques, surgeons are capable of more ..

..relevance for the investigation of promising new diagnostic and therapeutic strategies for chronic salivary gland diseases. This study reports the first experiences with scintigraphic analyses of salivary gland function in a rat ..

..This article continues a series of reviews, which aim to provide readers with a quick overview and update of recent publications in the British Journal of Oral and Maxillofacial Surgery (BJOMS) within a particular subspecialty...

..Symptomatic treatment is systematic, whereas systemic treatment is limited to the active extra glandular forms. There is no international treatment consensus. Biologics are currently evaluated...

..This technique was shown to be a safe, effective and low-cost option, leading to complete resolution and no recurrence after 28 months of follow up...

..It offers the unique possibility for the assessment of intra-individual dose-dysfunction curves in patients with large variations in the radiation dose within the parotids...

..The aim of this study was to assess the utility of fine-needle aspiration biopsy (FNAB) in the diagnosis and treatment planning of the lesions of the salivary gland...

..This article describes the use of sialoendoscopy for diagnosis and treatment of strictures and kinks in the major salivary glands ducts...

..Thus, the syndromes, unrelated in many respects, underline the importance of normal salivation in the protection of teeth against tooth wear by erosion, attrition, and abrasion...

..To report 2 cases of coexisting mucous retention cyst and basal cell adenoma arising from the lining epithelium of the cyst...

..1532 +/- 0.0378) g, respectively (P < 0.05). CONCLUSIONS: These results suggest that the matrix metalloproteinase inhibitor BB-94 has a strong inhibitory effect on invasion and metastasis of salivary adenoid cystic carcinoma...

..Therefore, a classification of these pathologies is needed, allowing large series comparisons, for better diagnosis and treatment of salivary pathologies...

..It is also of interest to know which eye test contributes most to the diagnosis of SS. We investigated the performance of different tear tests and how these tests relate to common serologic and salivary tests in SS...

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..We report a parotid gland necrotizing sialometaplasia of a 17-year-old girl, possibly caused by primary vascular damage or vasculitis...

..Finally, pathophysiological considerations of salivary dysfunction in relation to some GI functions are considered...

..To assess the impact of oral lesions on quality of life (QOL) in HIV-positive (HIV+) individuals using the Oral Health Impact Profile (OHIP)...

..To describe the technique and examine the value of salivary stone extraction using a minimally invasive, radiologically guided approach as an alternative to salivary gland surgery for the treatment of benign salivary gland obstruction...

..Management of dry mouth includes hydration and use of mouthwash, sugarless gum, candy, and saliva substitutes. Dry nose can be managed with nasal sprays that moisten the nasal cavity...

..CONCLUSION: These results suggest that in alcoholics the activity of glandular cells, mainly in ductal epithelium, could be affected, modifying synthesis, transport and salivary secretions...

..This article discusses the different types of salivary gland conditions and the best methods of imaging for diagnosis...

..The results of these studies will ultimately lead to revolutionary treatment of salivary gland diseases.

..The resources (databases) and computational/modeling approaches will be applicable to other salivary gland diseases and biology...

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..This multidisciplinary approach will define the essential CI transport mechanisms involved in the production of saliva, which is necessary for addressing the challenge of treating salivary gland dysfunction. ..

..Correctly understanding this fundamental structure/function is critical to developing effective therapies. ..

..Furthermore, the results of these studies will provide a foundation for future studies to analyze the in vivo structure/function relationship of a given Cl transporter. ..

..Given the universality of PEM pathophysiology, this study's findings will be generalizable to subsets of U.S. children having 9 oral health disparities. ..

..It is the goal of the organizing team to encourage both growth and enrichment of this important field and to stimulate new strategies for studying salivary glands. ..

..In summary, the PEARL Network is uniquely positioned to establish and Maintain a PBRN that will conduct research studies designed to positively impact oral health. ..

..Ultimately, the information gained from these Aims will aid in the development of therapies to remedy various forms of salivary gland dysfunction. ..

..Aging, diabetes or stress results in poor oxygen supply to wounds and in slow or failed healing. We are studying this observation and testing a strategy to improve wound healing. ..

..This multidisciplinary approach will define the essential CI" transport mechanisms involved in the production of saliva, which is necessary for addressing the challenge of treating salivary gland dysfunction. ..

..The various components of TPOS are integrated through various mechanisms including a signature Oral Biology curriculum. TPOS trainees are expected to be highly prepared for successful and productive careers in Oral Science research. ..

..This work will lead to generation of new models for tissue engineering. ..

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..Insight gained from these studies may therefore aid in developing rationales for preventing and/or treating salivary gland dysfunctions caused by a myriad of perturbations...

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..Defining HCO3 ion-transport and its relevance to CFTR function should lend much to explaining, and hopefully, ameliorating these problems. ..

..Insight gained from these studies may therefore aid in developing rationales for preventing and/or treating salivary gland dysfunctions...

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..Correctly understanding this fundamental structure/function is critical to developing effective therapies. ..

..Given the universality of PEM pathophysiology, this study's findings will be generalizable to subsets of U.S. children having oral health disparities. ..