oral lichen planus

Summary

Summary: Oral lesions accompanying cutaneous lichen planus or often occurring alone. The buccal mucosa, lips, gingivae, floor of the mouth, and palate are usually affected (in a descending order of frequency). Typically, oral lesions consist of radiating white or gray, velvety, threadlike lines, arranged in a reticular pattern, at the intersection of which there may be minute, white, elevated dots or streaks (Wickham's striae). (Jablonski, Illustrated Dictionary of Dentistry)

Top Publications

  1. ncbi Clinical behaviour of malignant transforming oral lichen planus
    M D Mignogna
    Department of Oral Medicine and Pathology, University of Naples Federico II, Faculty of Medicine, School of Dentistry, Naples, Italy
    Eur J Surg Oncol 28:838-43. 2002
  2. ncbi Oral lichen planus and dental materials: a case-control study
    Michael D Martin
    Department of Oral Medicine, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    Contact Dermatitis 48:331-6. 2003
  3. ncbi Heat-shock protein expression and topical treatment with tacrolimus in oral lichen planus: an immunohistochemical study
    F Tavassol
    Department of Oral and Maxillofacial Surgery, Hanover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Int J Oral Maxillofac Surg 37:66-9. 2008
  4. ncbi The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial
    C Choonhakarn
    Division of Dermatology, Department of Medicine, Srinagarind Hospital Medical School, Faculty of Medicine, Khon Khaen University, Khon Kaen 40002, Thailand
    Br J Dermatol 158:573-7. 2008
  5. ncbi Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation
    Sumairi B Ismail
    Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
    J Oral Sci 49:89-106. 2007
  6. ncbi Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications
    E H van der Meij
    Department of Oral and Maxillofacial Surgery Oral Pathology, Academic Centre for Dentistry Amsterdam, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    J Oral Pathol Med 32:507-12. 2003
  7. ncbi Number V Oral lichen planus: clinical features and management
    D Eisen
    Dermatology Research Associates, Cincinnati, OH 45230, USA
    Oral Dis 11:338-49. 2005
  8. ncbi The reported prevalence of oral lichen planus: a review and critique
    B E McCartan
    Department of Anatomy, Faculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland
    J Oral Pathol Med 37:447-53. 2008
  9. ncbi Expression profile of chemokines and chemokine receptors in epithelial cell layers of oral lichen planus
    Mana Ichimura
    Department of Microbiology and Immunology, Nihon University School of Dentistry at Matsudo, Chiba, Japan
    J Oral Pathol Med 35:167-74. 2006
  10. ncbi Association between psychological disorders and the presence of Oral lichen planus, Burning mouth syndrome and Recurrent aphthous stomatitis
    Milena Soto Araya
    Med Oral 9:1-7. 2004

Research Grants

  1. Oramelts with DGL: Treatment of Minor RAU
    Michael Martin; Fiscal Year: 2004
  2. CD80 binding peptides as therapeutic agents in arthritis
    Mythily Srinivasan; Fiscal Year: 2006
  3. Candida-endothelial interactions under conditions of flow
    Martin Thornhill; Fiscal Year: 2007

Detail Information

Publications248 found, 100 shown here

  1. ncbi Clinical behaviour of malignant transforming oral lichen planus
    M D Mignogna
    Department of Oral Medicine and Pathology, University of Naples Federico II, Faculty of Medicine, School of Dentistry, Naples, Italy
    Eur J Surg Oncol 28:838-43. 2002
    At present oral lichen planus (OLP) is classified among precancerous conditions but very few data are available in literature regarding prognosis of OLP-related cancers...
  2. ncbi Oral lichen planus and dental materials: a case-control study
    Michael D Martin
    Department of Oral Medicine, School of Dentistry, University of Washington, Seattle, WA 98195, USA
    Contact Dermatitis 48:331-6. 2003
    The purpose of this study was to examine the association of dental materials with oral lichen planus (OLP) and, particularly, the effects of amalgam, amalgam corrosion status, gold and dissimilar metals in continuous contact...
  3. ncbi Heat-shock protein expression and topical treatment with tacrolimus in oral lichen planus: an immunohistochemical study
    F Tavassol
    Department of Oral and Maxillofacial Surgery, Hanover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Int J Oral Maxillofac Surg 37:66-9. 2008
    b>Oral lichen planus (OLP) is a chronic inflammatory mucosal disease of unknown etiology. Usually asymptomatic, the disorder is occasionally complicated by extensive painful erosions...
  4. ncbi The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial
    C Choonhakarn
    Division of Dermatology, Department of Medicine, Srinagarind Hospital Medical School, Faculty of Medicine, Khon Khaen University, Khon Kaen 40002, Thailand
    Br J Dermatol 158:573-7. 2008
    b>Oral lichen planus (OLP) is a chronic inflammatory disease that can be painful especially in the atrophic and erosive forms. Several therapies have been tried, with varying results...
  5. ncbi Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management and malignant transformation
    Sumairi B Ismail
    Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia
    J Oral Sci 49:89-106. 2007
    Lichen planus, a chronic autoimmune, mucocutaneous disease affects the oral mucosa (oral lichen planus or OLP) besides the skin, genital mucosa, scalp and nails...
  6. ncbi Lack of clinicopathologic correlation in the diagnosis of oral lichen planus based on the presently available diagnostic criteria and suggestions for modifications
    E H van der Meij
    Department of Oral and Maxillofacial Surgery Oral Pathology, Academic Centre for Dentistry Amsterdam, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    J Oral Pathol Med 32:507-12. 2003
    Confirmation of a clinical diagnosis of oral lichen planus (OLP) by means of histopathologic study of a biopsy specimen is generally advised...
  7. ncbi Number V Oral lichen planus: clinical features and management
    D Eisen
    Dermatology Research Associates, Cincinnati, OH 45230, USA
    Oral Dis 11:338-49. 2005
    b>Oral lichen planus (OLP) is a relatively common chronic inflammatory disorder affecting stratified squamous epithelia...
  8. ncbi The reported prevalence of oral lichen planus: a review and critique
    B E McCartan
    Department of Anatomy, Faculty of Medicine and Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland
    J Oral Pathol Med 37:447-53. 2008
    To examine all studies reporting prevalences of oral lichen planus (OLP) for epidemiological validity and to extract prevalence data from the valid papers.
  9. ncbi Expression profile of chemokines and chemokine receptors in epithelial cell layers of oral lichen planus
    Mana Ichimura
    Department of Microbiology and Immunology, Nihon University School of Dentistry at Matsudo, Chiba, Japan
    J Oral Pathol Med 35:167-74. 2006
    To understand the immunopathological features of oral lichen planus (OLP), we analyzed the expression of chemokines in the epithelial cell layers.
  10. ncbi Association between psychological disorders and the presence of Oral lichen planus, Burning mouth syndrome and Recurrent aphthous stomatitis
    Milena Soto Araya
    Med Oral 9:1-7. 2004
    The aim of this study was to determine the existing relation between the Oral Lichen Planus (OLP), Recurrent Aphthous Stomatitis (RAS), Burning Mouth Syndrome (BMS) and psychological alterations of the patient, such as stress, anxiety and ..
  11. pmc The prevalence of hepatitis C virus infection in oral lichen planus in an ethnic Chinese cohort of 232 patients
    Yu Zhou
    State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, China
    Int J Oral Sci 2:90-7. 2010
    ..In this study, we investigated the prevalence of HCV in patients with oral lichen planus in an ethnic Chinese
  12. ncbi Candida in oral lichen planus patients undergoing topical steroid therapy
    Aree Jainkittivong
    Department of Oral Medicine, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:61-6. 2007
    To determine the incidence, intensity, and species of Candida in the oral cavity of oral lichen planus (OLP) patients who were being treated with a topical steroid.
  13. ncbi Oral lichen planus: a clinical and morphometric study of oral lesions in relation to clinical presentation
    Juan Seoane
    Stomatology Department, School of Medicine and Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain
    Braz Dent J 15:9-12. 2004
    b>Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical presentations that can be classified as reticular or atrophic-erosive...
  14. ncbi Angiogenesis of oral lichen planus: a possible pathogenetic mechanism
    Giuseppe Alessandro Scardina
    University of Palermo, Department of Oral Sciences G Messina, Palermo, Italy
    Med Oral Patol Oral Cir Bucal 14:e558-62. 2009
    b>Oral Lichen Planus (OLP) is a chronic inflammatory disease with an autoimmune inflammatory pathogenesis...
  15. ncbi Amalgam-contact hypersensitivity lesions and oral lichen planus
    Martin H Thornhill
    Department of Dental Diagnostic Science, University of Texas Health Science Center San Antonio, 78229 3900, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 95:291-9. 2003
    The purpose of this study was to investigate the relationship between amalgam restorations and oral lichen planus.
  16. ncbi Apoptosis of oral epithelial cells in oral lichen planus caused by upregulation of BMP-4
    S G Kim
    Department of Oral and Maxillofacial Surgery, College of Medicine, Hallym University, Anyang, Korea
    J Oral Pathol Med 35:37-45. 2006
    ..The objective of this study is to determine whether BMP-4 is involved in apoptosis, one characteristic, of human oral lichen planus (OLP).
  17. ncbi Histochemical analysis of pathological alterations in oral lichen planus and oral lichenoid lesions
    Manish Juneja
    Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Mangalore, Karnataka, India
    J Oral Sci 48:185-93. 2006
    ..cells (intact cells and degranulated cells subepithelially) and the presence or absence of blood vessels in oral lichen planus and oral lichenoid lesions...
  18. ncbi Nitrative and oxidative DNA damage in oral lichen planus in relation to human oral carcinogenesis
    Ponlatham Chaiyarit
    Department of Oral Diagnosis, Faculty of Dentistry, Khon Kaen University, Khon Kaen, 40002, Thailand
    Cancer Sci 96:553-9. 2005
    b>Oral lichen planus (OLP) is a chronic inflammatory disease, which has been clinically associated with development to oral cancer...
  19. ncbi The feasibility of monitoring NF-kappaB associated cytokines: TNF-alpha, IL-1alpha, IL-6, and IL-8 in whole saliva for the malignant transformation of oral lichen planus
    Nelson L Rhodus
    Division of Oral Medicine, University of Minnesota School of Dentistry, 7 536 Moos Tower, 515 Delaware Street SE, Minneapolis, MN 55455, USA
    Mol Carcinog 44:77-82. 2005
    ..of NF-kappaB dependent cytokines, TNF-alpha, IL-1alpha, IL-6, and IL-8 in different oral fluids from oral lichen planus (OLP) patients...
  20. ncbi A comparison of the pro-inflammatory, NF-kappaB-dependent cytokines: TNF-alpha, IL-1-alpha, IL-6, and IL-8 in different oral fluids from oral lichen planus patients
    Nelson L Rhodus
    Division of Oral Medicine, Oral Diagnosis and Radiology, Department of Diagnostic and Surgical Sciences, School of Dentistry, University of Minnesota, 7 536 Moos Tower, 515 Delaware Street S E, Minneapolis, MN 55455, USA
    Clin Immunol 114:278-83. 2005
    ..the feasibility of detection of the level of NF-kappaB-dependent cytokines in oral fluids from patient with oral lichen planus (OLP) for clinical application, 13 OLP subjects were enrolled in the study as were 13 age-sex-matched ..
  21. ncbi The evaluation of anxiety and salivary cortisol levels in patients with oral lichen planus
    M Koray
    Department of Oral Medicine and Oral Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey
    Oral Dis 9:298-301. 2003
    The aim of this study was to determine any association between anxiety and salivary cortisol levels in oral lichen planus (OLP) patients by the case-control method. DESIGN RELEVANT: Forty patients with OLP were evaluated...
  22. ncbi Pathophysiology, etiologic factors, and clinical management of oral lichen planus, part I: facts and controversies
    David Farhi
    Department of Dermatology and Venereology, Hopital Cochin, APHP, Université Descartes Paris 5, Pavillon Tarnier, 75006 Paris, France
    Clin Dermatol 28:100-8. 2010
    ..The first-line pharmacologic treatment relies on topical steroids. Systemic steroids should be limited to the short-term cure of severe refractory OLP. Life-long clinical follow-up, at least annually, is fundamental...
  23. ncbi Distribution of interleukin-2, -4, -10, tumour necrosis factor-alpha and transforming growth factor-beta mRNAs in oral lichen planus
    C Simark-Mattsson
    Department of Endodontology Oral Diagnosis, Goteborg University, Sweden
    Arch Oral Biol 44:499-507. 1999
    ..necrosis factor-alpha (TNF-alpha) and transforming growth factor beta-1 (TGF-beta-1) were investigated in oral lichen planus (OLP) lesions using in situ hybridization with 35S-labelled oligonucleotide probes on frozen tissue sections...
  24. ncbi Association of polymorphisms in the human IFN-gamma and IL-4 gene with oral lichen planus: a study in an ethnic Chinese cohort
    Jingping Bai
    State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, Chengdu, China
    J Interferon Cytokine Res 28:351-8. 2008
    Cytokines have an important role in the pathogenesis and disease progression of oral lichen planus (OLP)...
  25. ncbi Decreased expression of the p63 related proteins beta-catenin, E-cadherin and EGFR in oral lichen planus
    Majid Ebrahimi
    Department of Odontology, Umea University, Umea, Sweden
    Oral Oncol 44:634-8. 2008
    b>Oral lichen planus (OLP) is a chronic inflammatory disease and although classified by WHO as a premalignant condition, the risk for transformation into squamous cell carcinoma of the head and neck (SCCHN) is a matter of great controversy...
  26. ncbi Interleukin-18 gene polymorphisms and haplotypes in patients with oral lichen planus: a study in an ethnic Chinese cohort
    J Bai
    State Key Laboratory for Dental Medicines and West China College of Stomatology, Sichuan University, Chengdu, Sichuan, China
    Tissue Antigens 70:390-7. 2007
    ..and cytotoxic T-lymphocyte functions, both of which have been proposed in the pathogenesis of oral lichen planus (OLP) - an oral disease resembles oral mucosal graft-versus-host disease (GVHD) both clinically and ..
  27. ncbi The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective five-year follow-up study of 192 patients
    E H van der Meij
    Department of Oral and Maxillofacial Surgery, Erasmus Medical Centre, Postbus 2040, 3000 CA, Rotterdam, The Netherlands
    Oral Oncol 43:742-8. 2007
    ..Recently, we reported the preliminary results of a prospective study on the possible premalignant character of oral lichen planus (OLP) and oral lichenoid lesions (OLL)...
  28. ncbi Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations
    Ibtisam Al-Hashimi
    Salivary Dysfunction Clinic, Baylor College of Dentistry, Houston, TX, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:S25.e1-12. 2007
    Several therapeutic agents have been investigated for the treatment of oral lichen planus (OLP). Among these are corticosteroids, retinoids, cyclosporine, and phototherapy, in addition to other treatment modalities...
  29. ncbi Microbiological findings in subjects with asymptomatic oral lichen planus: a cross-sectional comparative study
    Michael M Bornstein
    Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, Bern, Switzerland
    J Periodontol 79:2347-55. 2008
    The bacterial colonization of the oral mucosa was evaluated in patients with asymptomatic oral lichen planus (OLP) and compared to the microbiologic status in mucosally healthy subjects.
  30. pmc Infiltrating CD8+ T cells in oral lichen planus predominantly express CCR5 and CXCR3 and carry respective chemokine ligands RANTES/CCL5 and IP-10/CXCL10 in their cytolytic granules: a potential self-recruiting mechanism
    Wakana Iijima
    Division of Oral Diagnosis and Radiology, Tohoku University Graduate School of Dentistry, Sendai, Japan
    Am J Pathol 163:261-8. 2003
    ..further, the present study examined the in situ expression of chemokines and chemokine receptors in oral lichen planus. Immunohistochemical analysis of 15 cases has consistently revealed that infiltrating CD4(+) and CD8(+) T ..
  31. ncbi A retrospective clinicopathological study of 550 patients with oral lichen planus in south-eastern Spain
    A Bermejo-Fenoll
    Mariano Sánchez Siles, Clinica Odontologica Universitaria, Medicina Bucal, Hospital Morales Meseguer, Murcia, Spain
    J Oral Pathol Med 39:491-6. 2010
    This study describes the clinicopathological characteristics of a group of patients with oral lichen planus (OLP) in south-eastern Spain.
  32. ncbi Association of interleukin-8 gene polymorphisms and haplotypes with oral lichen planus in a Chinese population
    Hongxia Dan
    State Key Laboratory of Oral Diseases, West China College of Stomatology, Sichuan University, No 14, Section 3, Renminnan Road, Chengdu, Sichuan, 610041, China
    Inflammation 33:76-81. 2010
    ..IL-8), a CXC chemokine with multiple biological functions, plays an important role in the pathogenesis of oral lichen planus (OLP)...
  33. ncbi Psychosocial stressors in oral lichen planus
    S Chaudhary
    Department of Oral Medicine and Radiology, ITS Centre for Dental Studies and Research, Murad nagar, Ghaziabad, India
    Aust Dent J 49:192-5. 2004
    ..factors and their association with dermatological disorders are well recognized, yet their importance in oral lichen planus (OLP) is still debated...
  34. ncbi Association of polymorphisms in the tumor necrosis factor-alpha and interleukin-10 genes with oral lichen planus: a study in a chinese cohort with Han ethnicity
    Jingping Bai
    Beijing Stomatology Hospital, Capital Medical University, Beijing, People s Republic of China
    J Interferon Cytokine Res 29:381-8. 2009
    Cytokines have an important role in the pathogenesis and disease progression on oral lichen planus (OLP)...
  35. ncbi Apoptosis and cell cycle arrest in oral lichen planus Hypothesis on their possible influence on its malignant transformation
    C Bascones
    Departamento de Estomatologia, Facultad de Odontologia, Universidad de Madrid, Complutense University, Madrid, Spain
    Arch Oral Biol 50:873-81. 2005
    The quantitative importance of cell cycle arrest and apoptosis mechanisms in oral lichen planus (OLP) was analysed in order to assess the cell response to T lymphocyte aggression and establish a hypothesis on the influence of these ..
  36. ncbi Oral lichen planus and hepatitis C virus infection
    L C Figueiredo
    Department of Oral Diagnosis, University of Sao Paulo School of Dentistry, Brazil
    Oral Dis 8:42-6. 2002
    This investigation was conducted to determine the possible association between oral lichen planus (OLP) and hepatitis C virus infection (HCV) in the population of São Paulo (Brazil).
  37. ncbi Erosive oral lichen planus with genital lesions: the vulvovaginal-gingival syndrome and the peno-gingival syndrome
    Roy S Rogers
    Department of Dermatology, Mayo Clinic, 200 First Street SW Rochester, MN 55905 0001, USA
    Dermatol Clin 21:91-8, vi-vii. 2003
    ..This article describes patients with the unique chronic orogenital variant of erosive oral lichen planus in both women and men...
  38. ncbi Assessment of local angiogenesis and vascular endothelial growth factor in the patients with atrophic-erosive and reticular oral lichen planus
    Xiaoan Tao
    Department of Oral Medicine, Guanghua School of Stomatology, Sun Yat Sen University, Guangzhou, Guangdong, PR China
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 103:661-9. 2007
    The objective of this study was to assess local angiogenesis and expression of VEGF in atrophic-erosive and reticular oral lichen planus (OLP).
  39. ncbi Differences in the expression of p53 protein in oral lichen planus based on the use of monoclonal antibodies DO7 and pAb 240
    M A Gonzalez-Moles
    Oral Medicine, Dental School, Granada University, Spain
    Oral Oncol 44:496-503. 2008
    A comparison is made of p53 expression in oral lichen planus, detected via monoclonal antibodies pAb240 and DO7, and with cell apoptosis and proliferation markers...
  40. ncbi Malignant transformation of oral lichen planus: a retrospective study of 23 cases
    Meixian Fang
    Department of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu, China
    Quintessence Int 40:235-42. 2009
    b>Oral lichen planus (OLP) is a common mucocutaneous disease with malignant transformation potential...
  41. ncbi Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: a follow-up study in an Italian population
    S Gandolfo
    Department of Biomedical Sciences and Oncology, Section of Oral Medicine, School of Medicine and Dentistry, University of Turin, Turin, Italy
    Oral Oncol 40:77-83. 2004
    The most important complication of oral lichen planus (OLP) is the development of oral squamous cell carcinoma (OSCC) but this is a very controversial matter...
  42. ncbi Matrix metalloproteinase gene expression in oral lichen planus: erosive vs. reticular forms
    N Mazzarella
    Department of Odontostomatological, Medical School II, University of Naples, Via L De Crecchio 7, 80128 Naples, Italy
    J Eur Acad Dermatol Venereol 20:953-7. 2006
    b>Oral lichen planus (OLP) is an autoimmune disease of unknown aetiology...
  43. ncbi Increased frequency of HLA-DR6 allele in Italian patients with hepatitis C virus-associated oral lichen planus
    M Carrozzo
    Department of Oral Medicine, School of Medicine and Dentistry, University of Turin, C so Dogliotti 14, I 10126 Turin, Italy
    Br J Dermatol 144:803-8. 2001
    ..Thus host rather than viral factors may be prevalent in the pathogenesis of HCV-related LP. The HLA-DR allele may influence both the outcome of HCV infection and the appearance of symptoms outside the liver...
  44. ncbi hTR RNA component as a marker of cellular proliferation in oral lichen planus
    Cathal O Flatharta
    Molecular Oncology Laboratory, Beaumont Hospital and The Royal College of Surgeons, Ireland
    Asian Pac J Cancer Prev 9:287-90. 2008
    ..we have shown that the telomerase RNA component hTR is highly expressed in the epithelium of non-dysplastic Oral Lichen Planus (OLP) lesions (11)...
  45. ncbi A histochemical and immunohistochemical study of mast cells in differentiating oral lichen planus from oral lichenoid reactions
    Gholamreza Jahanshahi
    Department of Oral Pathology, School of Dentistry, University of Medical Sciences, Esfahan, Iran
    Quintessence Int 41:221-7. 2010
    b>Oral lichen planus (OLP) is a chronic mucocutaneous disease with unknown etiology. Oral lichenoid reactions (OLRs) comprise a family of lesions with different recognized etiologies...
  46. ncbi Cell cycle regulating mechanisms in oral lichen planus: molecular bases in epithelium predisposed to malignant transformation
    M A Gonzalez-Moles
    School of Dentistry, Granada University, Paseo de Cartuja s n, 18071 Granada, Spain
    Arch Oral Biol 51:1093-103. 2006
    Expression of p53, p21, ki-67, Bcl-2 and caspase-3 proteins in oral lichen planus (OLP) was studied to investigate cell cycle regulation mechanisms in this disease.
  47. ncbi Intra-epithelial CD8+ T cells and basement membrane disruption in oral lichen planus
    Xijing J Zhou
    Oral Biology and Pathology, School of Dentistry, The University of Queensland, Brisbane, Australia
    J Oral Pathol Med 31:23-7. 2002
    ..basement membrane (BM) disruption and the distribution of mast cells (MCs) and T cell subsets, in oral lichen planus (OLP) and normal buccal mucosa (NBM) using immunohistochemistry...
  48. ncbi Significance of liquefaction degeneration in oral lichen planus: a study of its relationship with apoptosis and cell cycle arrest markers
    C Bascones-Ilundain
    Department of Periodontics and Dentistry, Complutense University, Madrid, Spain
    Clin Exp Dermatol 32:556-63. 2007
    To assess the utility of liquefaction degeneration as a marker of apoptosis in oral lichen planus (OLP).
  49. ncbi Oral lichen planus: a retrospective study of 690 British patients
    M Ingafou
    Oral Medicine, Division of Maxillofacial Diagnostic, Medical and Surgical Sciences, UCL, Eastman Dental Institute, London, UK
    Oral Dis 12:463-8. 2006
    This is the largest UK patient group with oral lichen planus (OLP) to be studied in terms of the demographic and clinical characteristics.
  50. ncbi Current controversies in oral lichen planus: report of an international consensus meeting. Part 1. Viral infections and etiopathogenesis
    Giovanni Lodi
    Department of Medicine, Surgery, and Dentistry, University of Milan, Italy
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:40-51. 2005
    Despite recent advances in understanding the immunopathogenesis of oral lichen planus (LP), the initial triggers of lesion formation and the essential pathogenic pathways are unknown...
  51. ncbi NF-kappaB-dependent cytokines in saliva and serum from patients with oral lichen planus: a study in an ethnic Chinese population
    Yuanyuan Zhang
    National Key Laboratory of Stomatology and West China College of Stomatology, Sichuan University, No 14, Sec 3, Renminnan Road, Chengdu, Sichuan 610041, China
    Cytokine 41:144-9. 2008
    ..including tumor necrosis factor-alpha (TNF-alpha), interleukin-6(IL-6), and interleukin-8(IL-8), in oral lichen planus (OLP), and to explore whether salivary detection of these cytokines is a better monitoring tool than serum ..
  52. ncbi The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective study
    Erik H van der Meij
    Department of Oral and Maxillofacial Surgery, Academic Centre for Dentistry Amsterdam, The Netherlands
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:164-71. 2003
    The possible malignant transformation of oral lichen planus (OLP) is the subject of an ongoing and controversial discussion in the literature...
  53. ncbi Evaluation of salivary cortisol and psychological factors in patients with oral lichen planus
    Bina Shah
    Department of Oral Medicine and Radiology, Bapuji Dental College and Hospital, Davangere, India
    Indian J Dent Res 20:288-92. 2009
    ..Recent studies have been conflicting, and hence, in the present study, evaluation of salivary cortisol levels and psychosocial factors in oral lichen planus (OLP) patients was done.
  54. ncbi Oral lichen planus: controversies surrounding malignant transformation
    M A Gonzalez-Moles
    Oral Medicine Department, Faculty of Dentistry, University of Granada, Granada, Spain
    Oral Dis 14:229-43. 2008
    Studies of the malignant potential of oral lichen planus (OLP) have been hampered by inconsistencies in the diagnostic criteria used for OLP, the criteria adopted to identify a true case of malignant transformation in OLP, the risk ..
  55. ncbi Oral Lichen Planus: a retrospective study of 420 Iranian patients
    Atessa Pakfetrat
    Oral Medicine Department, School of Dentistry and Dental Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
    Med Oral Patol Oral Cir Bucal 14:E315-8. 2009
    In terms of the demographic and clinical characteristics, this is the one of the largest studies on Iranian patients with Oral Lichen Planus (OLP).
  56. ncbi Course of oral lichen planus: a retrospective study of 808 northern Italian patients
    M Carbone
    Department of Biological Sciences and Human Oncology, Oral Medicine Section, University of Turin, Turin, Italy
    Oral Dis 15:235-43. 2009
    To undertake a retrospective inspection of the general features, clinical presentation and outcome of 808 Italian patients with oral lichen planus (OLP), followed up from 6 months to 17 years.
  57. ncbi Th1 cytokines in oral lichen planus
    Ambereen Khan
    Oral Biology and Pathology, The University of Queensland, St Lucia, Brisbane, Queensland, Australia
    J Oral Pathol Med 32:77-83. 2003
    Cell-mediated immune responses in oral lichen planus (OLP) may be regulated by cytokines and their receptors.
  58. ncbi The pathogenesis of oral lichen planus
    P B Sugerman
    AstraZeneca R and D Boston, 35 Gatehouse Drive, Waltham, MA 02451, USA
    Crit Rev Oral Biol Med 13:350-65. 2002
    Both antigen-specific and non-specific mechanisms may be involved in the pathogenesis of oral lichen planus (OLP)...
  59. pmc Expression of novel p53 isoforms in oral lichen planus
    Majid Ebrahimi
    Department of Odontology, Umea University, SE 901 85 Umea, Sweden
    Oral Oncol 44:156-61. 2008
    b>Oral lichen planus (OLP) is a chronic inflammatory disease of unknown origin, showing little spontaneous regression...
  60. pmc Th1/Th2 cytokine ratio in tissue transudates from patients with oral lichen planus
    Nelson L Rhodus
    Division of Oral Medicine and Diagnosis, Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN 55455, USA
    Mediators Inflamm 2007:19854. 2007
    The characteristics of oral lichen planus (OLP) provoke investigators to explore possible biomarkers by which to monitor disease activity and therapeutic efficacy...
  61. ncbi Changes in the expression of stem cell markers in oral lichen planus and hyperkeratotic lesions
    Osman Kose
    Programme in Muco Cutaneous Oncology, Department of Clinical and Diagnostic Oral Sciences, Barts and The London NHS Trust, Queen Mary s School of Medicine and Dentistry, Institute of Cell and Molecular Science, London, UK
    J Oral Sci 49:133-9. 2007
    ..Samples of normal oral mucosa (NOM), hyperkeratosis (OHK) and oral lichen planus (OLP) were immunostained for alpha6 and beta1 integrins, keratin 15 (K15), melanoma-associated chondroitin ..
  62. ncbi Mast cell degranulation and the role of T cell RANTES in oral lichen planus
    Z Z Zhao
    School of Dentistry, The University of Queensland, Brisbane, Australia
    Oral Dis 7:246-51. 2001
    OBJECTIVES: The present study investigated mast cell degranulation in oral lichen planus (OLP) and the effect of OLP lesional T cell supernatants on mast cell degranulation...
  63. ncbi Clinical guidelines in early detection of oral squamous cell carcinoma arising in oral lichen planus: a 5-year experience
    M D Mignogna
    Department of Oral Medicine and Pathology, Faculty of Medicine, School of Dentistry, University of Naples Federico II, Via Domenico Fontana 81 pal 10, 80128, Naples
    Oral Oncol 37:262-7. 2001
    In recent years, studies on the malignant potential of oral lichen planus (OLP) provided clinical evidence that patients affected by OLP have an increased risk to develop oral squamous cell carcinoma (OSCC); nevertheless, controversies ..
  64. ncbi Oral lichen planus in childhood
    Ronald Laeijendecker
    Department of Dermatology, Albert Schweitzer Hospital, Albert, Schweitzerplaats, The Netherlands
    Pediatr Dermatol 22:299-304. 2005
    b>Oral lichen planus is rare in childhood, and only a few reports on this subject have appeared in the literature...
  65. ncbi Randomized trial of pimecrolimus cream versus triamcinolone acetonide paste in the treatment of oral lichen planus
    Farzam Gorouhi
    Center for Research and Training in Skin Diseases and Leprosy, Medical Sciences University of Tehran, Tehran, Iran
    J Am Acad Dermatol 57:806-13. 2007
    ..1% to 4% of the general population. There is no published randomized active control clinical trial on pimecrolimus for the treatment of oral lichen planus (OLP).
  66. ncbi Oral lichen planus: clinical presentation and management
    Paul C Edwards
    Department of Dental Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA
    J Can Dent Assoc 68:494-9. 2002
    b>Oral lichen planus (OLP) is a chronic mucosal condition commonly encountered in clinical dental practice...
  67. ncbi Matrix metalloproteinases and their inhibitors in oral lichen planus
    X J Zhou
    Oral Biology and Pathology, School of Dentistry, The University of Queensland, Brisbane, Australia
    J Cutan Pathol 28:72-82. 2001
    BACKGROUND: Oral lichen planus (OLP) is characterized by a sub-epithelial lymphocytic infiltrate, basement membrane (BM) disruption, intra-epithelial T-cell migration and apoptosis of basal keratinocytes...
  68. pmc Salivary levels of tumor necrosis factor-alpha in oral lichen planus
    Sonja Pezelj-Ribaric
    Department of Oral Medicine, Medical Faculty, University of Rijeka, Croatia
    Mediators Inflamm 13:131-3. 2004
    b>Oral lichen planus (OLP) is chronic inflammatory disease of the oral mucosa, presenting in various clinical forms. The etiology of OLP is still unknown but mounting evidence points to the immunologic basis of this disorder.
  69. ncbi Apoptosis in oral lichen planus
    E Neppelberg
    Institute of Odontology, Oral Pathology and Forensic Odontology, University of Bergen, Norway
    Eur J Oral Sci 109:361-4. 2001
    Apoptotic cell death may be a contributory cause of basal cell destruction in oral lichen planus (OLP). Therefore...
  70. ncbi Correlation between clinical and histopathologic diagnoses of oral lichen planus based on modified WHO diagnostic criteria
    Maryam Rad
    Department of Oral Medicine, Kerman School of Dentistry, Kerman Oral and Dental Diseases Research Center, Kerman, Iran
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:796-800. 2009
    We studied the correlation between the clinical and histopathologic diagnoses of oral lichen planus (OLP) based on the modified World Health Organization (WHO) diagnostic criteria (2003).
  71. ncbi Oral lichen planus and hepatitis C virus: is there real association?
    Ahmad Al Robaee A Al Robaee
    Department of Medicine, College of Medicine, Qassim University, P O Box 30109, Buraidah 51477 Saudi Arabia
    Acta Dermatovenerol Alp Pannonica Adriat 15:14-9. 2006
    ..In recent years, several reports have supposed a relationship between oral lichen planus (OLP) and chronic liver disease, especially hepatitis C (HCV)...
  72. ncbi Oral lichen planus versus oral lichenoid reaction: difficulties in the diagnosis
    Renata Falchete do Prado
    Department of Biosciences and Oral Diagnosis at São José dos Campos Dental School, Sao Paulo State University UNESP, Sao Jose dos Campos, Sao Paulo, Brazil
    Indian J Dent Res 20:361-4. 2009
    ..The treatment of LP comprises mainly the utilization of corticosteroids and the LR is treated by removal of the causal factor. Differentiation between the two diseases allows an effective and correct therapeutic approach...
  73. ncbi Cancer and oral lichen planus in a Swedish population
    Per Olof Rödström
    Clinic of Oral Medicine, Department of Endodontology and Oral Diagnosis, Faculty of Odontology, Goteborg University, Medicinaregatan 12, Box 450, SE 405 30 Goteborg, Sweden
    Oral Oncol 40:131-8. 2004
    b>Oral lichen planus (OLP) is generally regarded as a premalignant condition...
  74. ncbi HPA-suppressive effects of aqueous clobetasol propionate in the treatment of patients with oral lichen planus
    M A Gonzalez-Moles
    Oral Medicine Department, School of Dentistry, Granada University, Granada, Spain
    J Eur Acad Dermatol Venereol 24:1055-9. 2010
    ..Oral topical corticosteroids have potential to produce inhibition of the hypothalamus-pituitary-adrenal (HPA) axis...
  75. ncbi Oxidative stress and antioxidant defense in oral lichen planus and oral lichenoid reaction
    Ram B Upadhyay
    Department of Oral and Maxillofacial Pathology, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, India
    Scand J Clin Lab Invest 70:225-8. 2010
    b>Oral Lichen Planus (OLP) is an inflammatory disease of unknown etiology while Oral Lichenoid Reaction (OLR) is a condition mimicking OLP...
  76. ncbi Quality of life in patients with oral lichen planus
    Pía López-Jornet
    Department of Oral Medicine, Faculty of Medicine and Dentistry, University of Murcia, Murcia, Spain
    J Eval Clin Pract 16:111-3. 2010
    b>Oral lichen planus (OLP) can seriously affect the quality of life of patients because it has a strong impact on social relations, psychological status and daily activities.
  77. ncbi Oral lichen planus and malignant transformation: a retrospective follow-up study of clinical and histopathologic data
    Michael M Bornstein
    Department of Oral Surgery and Stomatology, School of Dental Medicine, Berne, Switzerland
    Quintessence Int 37:261-71. 2006
    ..of the Department of Oral Surgery and Stomatology who were clinically and histopathologically diagnosed with oral lichen planus (OLP) in the years 1995 to 2001 were examined for a possible malignant transformation of a previously ..
  78. ncbi Oral lichen planus in childhood: A rare case report
    M GunaShekhar
    Vishnu Dental College and Hospital, NTRUHS, India
    Dermatol Online J 16:9. 2010
    b>Oral lichen planus is a cell-mediated immune condition and is infrequently encountered in children, with a prevalence of about 0.03 percent in childhood. Reports of oral lichen planus affecting children are scarce in the literature...
  79. ncbi Expression of Fas/FasL in patients with oral lichen planus
    M Hadzi-Mihailovic
    Clinic of Periodontology and Oral Medicine, Faculty of Dentistry, University of Belgrade, Belgrade, Serbia
    J BUON 14:487-93. 2009
    To investigate the malignant potential of oral lichen planus (OLP) on the basis of expression of the Fas/FasL markers in healthy individuals (H), OLP patients and patients with squamous cell carcinoma (SCC).
  80. ncbi Oral lichen planus. Clinical aspects and management in fifty-two Brazilian patients
    A C Machado
    Department of Oral Diagnosis, School of Dentistry, University of Sao Paulo, Brazil
    West Indian Med J 53:113-7. 2004
    This study aimed to characterize the clinical profile of patients with oral lichen planus (OLP) and to evaluate the efficacy of topical, systemic and/or intralesional corticosteroids in the management of symptomatic cases...
  81. ncbi Oral lichen planus: an overview
    Joachim Dissemond
    Department of Dermatology and Allergology, University of Essen, Germany
    J Dermatolog Treat 15:136-40. 2004
    ..Patients with symptomatic oral lichen planus (OLP) often require intensive therapy to reduce the signs and symptoms of this painful and disabling ..
  82. ncbi Expression of cytokeratins 10, 13, 14 and 19 in oral lichen planus
    Claudio M C Jacques
    Oral Dermatology Out Patient Clinic, Sector of Dermatology and Post Graduation Course, HUCFF UFRJ, and School of Medicine, Federal University of Rio de Janeiro, Brazil
    J Oral Sci 51:355-65. 2009
    ..The presence of mild dysplasia did not change the expression of the cytokeratins studied. No differences in pattern of expression were observed between keratinized and non-keratinized areas in the lesions caused by OLP...
  83. ncbi Treatment of erosive oral lichen planus with topical tacrolimus
    M A Thomson
    Department of Dermatology, Selly Oak Hospital, Birmingham, UK
    J Dermatolog Treat 15:308-14. 2004
    Erosive oral lichen planus (LP) is a painful chronic inflammatory condition that is frequently resistant to immunosuppressive agents. Topical tacrolimus has been reported as a safe and effective treatment.
  84. ncbi Oral lichen planus
    Michaell A Huber
    Division of Oral Medicine, Department of Dental Diagnostic Science, University of Texas Health Science Center at San Antonio, Dental School, San Antonio, Texas 78229 3900, USA
    Quintessence Int 35:731-52. 2004
    Lichen planus is the most common dermatologic disease with oral manifestations, and oral lichen planus (OLP) is one of the more common mucosal conditions a clinician is likely to encounter in his or her practice...
  85. ncbi Role of apoptosis in erosive and reticular oral lichen planus exhibiting variable epithelial thickness
    Juliana M Caldeira Brant
    Institute of Biological Sciences, Departament of General Pathology, Laboratory of Apoptosis, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil
    Braz Dent J 19:179-85. 2008
    b>Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical types. Reticular and erosive forms are the most common...
  86. ncbi A clinical study of 674 patients with oral lichen planus in China
    Jing Ling Xue
    Key Lab for Oral Biochemical Engineering of Ministry of Education, Stomatological College of Wuhan University, Luoyu Road 65, 430079 Wuhan, Hubei, China
    J Oral Pathol Med 34:467-72. 2005
    b>Oral lichen planus (OLP) is a chronic inflammatory disease with different clinical presentations that can be classified as reticular, atrophic or erosive...
  87. ncbi Prevalence of vulval lichen planus in a cohort of women with oral lichen planus: an interdisciplinary study
    P Belfiore
    Mother and Child Department, Gynaecology and Obstetrics Institute, Palermo, Italy
    Br J Dermatol 155:994-8. 2006
    ..There are few studies in the literature combining the experiences of these specialists who share the care of patients with both oral and genital LP...
  88. ncbi Oral lichen planus and malignant transformation: is a recall of patients justified?
    Ulf Mattsson
    Clinic of Oral and Maxillofacial Surgery and Hospital Dental Care, Central Hospital, Karlstad, Sweden
    Crit Rev Oral Biol Med 13:390-6. 2002
    There has been a continuous debate regarding the possible malignant potential of oral lichen planus (OLP)...
  89. ncbi Interobserver and intraobserver variability in the clinical assessment of oral lichen planus
    E H van der Meij
    Department of Oral and Maxillofacial Surgery Oral Pathology, Academic Centre for Dentistry Amsterdam ACTA Academic Hospital Vrije Universiteit, Amsterdam, The Netherlands
    J Oral Pathol Med 31:95-8. 2002
    ..To date, the validation results of this clinical definition have not been published. The aim of this study was to evaluate interobserver and intraobserver variability in the clinical assessment of oral lichen planus (OLP).
  90. ncbi Concurrent oral lichen planus and primary sclerosing cholangitis
    D C Tong
    Department of Stomatology, University of Otago, PO Box 647, Dunedin, New Zealand
    Br J Dermatol 147:356-8. 2002
    Four patients with concomitant oral lichen planus (OLP) and primary sclerosing cholangitis (PSC) are presented...
  91. ncbi Oral lichen planus: patient profile, disease progression and treatment responses
    N Chainani-Wu
    Department of Stomatology, School of Dentistry, University of California, San Francisco, USA
    J Am Dent Assoc 132:901-9. 2001
    b>Oral lichen planus, or OLP, is a common mucocutaneous immunological disease. The objective of this study was to describe the patient profile, disease progression and treatment responses.
  92. ncbi Topical tacrolimus in the treatment of symptomatic oral lichen planus: a series of 13 patients
    Todd W Rozycki
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota, USA
    J Am Acad Dermatol 46:27-34. 2002
    b>Oral lichen planus (OLP) is a relatively common, chronic inflammatory condition, which frequently presents with symptoms of pain and irritation. OLP is often difficult to manage...
  93. ncbi Immune mechanisms in oral lichen planus
    M H Thornhill
    Oral Disease Research Centre, Bart s and The London, Queen Mary School of Medicine and Dentistry, UK
    Acta Odontol Scand 59:174-7. 2001
    ..don't know the cause, there has been much research into the immune and pathological mechanisms that underlie oral lichen planus (OLP) and it is now possible to piece together a much clearer picture of the disease process...
  94. ncbi Malignant transformation of atypical oral lichen planus: a review of 32 cases
    Hector Eduardo Lanfranchi-Tizeira
    Catedra de Patologia y Clinica Bucodental II Facultad de Odontologia Universidad de Buenos Aires
    Med Oral 8:2-9. 2003
    ..To assess the prevalence of malignant transformation of atypical lichen planus in our medium and describe the clinico-pathological features of the cases that had a premalignant potential...
  95. ncbi Langerhans cells and T cells in oral graft versus host disease and oral lichen planus
    B Hassèus
    Department of Endodontology Oral diagnosis Clinic for oral medicine, Sahlgrenska University Hospital, Goteborg University, S 405 30 Goteborg, Sweden
    Scand J Immunol 54:516-24. 2001
    ..graft versus host disease (cGVHD) of the oral mucosa, following allogeneic stem cell transplantation, and oral lichen planus (OLP) are both mucosal diseases where the immune system is involved in the pathogenesis...
  96. ncbi Oral lichen planus pathogenesis: A role for the HCV-specific cellular immune response
    Massimo Pilli
    Divisione Malattie Infettive ed Epatologia, Azienda Ospedaliera Universitaria di Parma, Parma, Italy
    Hepatology 36:1446-52. 2002
    ..T cells were isolated from lichen biopsy specimens of 7 HCV positive patients with oral lichen planus. HCV-specific CD4(+) T-cell lines were obtained in 4 patients from lichen lesions but only in 2 of them from ..
  97. ncbi Lack of association between hepatotropic transfusion transmitted virus infection and oral lichen planus in British and Italian populations
    C Bez
    Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, UCL, University of London, UK
    Br J Dermatol 145:990-3. 2001
    BACKGROUND: A possible association between oral lichen planus (OLP) and chronic hepatic disease has been found in some populations, although this is probably geographically influenced...
  98. ncbi Incidence and treatment outcome of oral lichen planus in southeast Serbia in a 10-year period (1997-2007)
    Ljiljana Kesic
    School of Medicine, Department for Oral Medicine and Periodontology, Nis, Serbia
    Vojnosanit Pregl 66:435-9. 2009
    ..The aim of this retrospective study was to evaluate the most common forms of oral lichen planus (OLP) and its symptoms and to describe treatment responses in patients during 10-year period.
  99. ncbi Prevalence of Epstein-Barr virus in oral squamous cell carcinoma, oral lichen planus, and normal oral mucosa
    Lars Peter Sand
    Goteborg University, Angelholm Hospital, Goteborg, Angelholm, Sweden
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 93:586-92. 2002
    ..In several studies it has also been associated with oral squamous cell carcinoma (OSCC). Oral lichen planus (OLP) is a disease with unknown origin, and viral antigens have been proposed as etiologic agents...
  100. ncbi Immunohistochemical and serological comparison of idiopathic and hepatitis C virus-associated forms of oral lichen planus
    A C Kirby
    Department of Oral Medicine, Eastman Dental Institute for Oral Health Care Sciences, University of London, UK
    Eur J Oral Sci 106:853-62. 1998
    ..antigen-3 and intercellular adhesion molecule-1, but relatively elevated levels of these antigens in oral lichen planus patients with no hepatitis C virus infection...
  101. pmc Expression of matrix metalloproteinases (MMP-1 and -2) and their inhibitors (TIMP-1, -2 and -3) in oral lichen planus, dysplasia, squamous cell carcinoma and lymph node metastasis
    M Sutinen
    Department of Oral Maxillofacial Surgery, University of Oulu, Finland
    Br J Cancer 77:2239-45. 1998
    ..TIMPs -1, -2 and -3) in oral squamous cell carcinomas (SCC) and lymph node metastases as well as in oral lichen planus, epithelial dysplasias and normal buccal mucosa...

Research Grants4

  1. Oramelts with DGL: Treatment of Minor RAU
    Michael Martin; Fiscal Year: 2004
    ..If these claims are verified in clinical trials, Orahealth Corporation will take the product to market, providing health benefits to the 20% of people who suffer from minor recurrent aphthous ulcers. ..
  2. CD80 binding peptides as therapeutic agents in arthritis
    Mythily Srinivasan; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  3. Candida-endothelial interactions under conditions of flow
    Martin Thornhill; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..