parotid neoplasms

Summary

Summary: Tumors or cancer of the PAROTID GLAND.

Top Publications

  1. pmc An invasive adenocarcinoma of the accessory parotid gland: a rare example developing from a low-grade cribriform cystadenocarcinoma?
    Shin ichi Nakatsuka
    Department of Pathology, Kansai Rosai Hospital, 3 1 69 Inabaso, Amagasaki, Hyogo 660 8511, Japan
    Diagn Pathol 6:122. 2011
  2. pmc Dendritic cell tumor in a salivary gland lymph node: a rare differential diagnosis of salivary gland neoplasms
    Sebastian P Schraven
    Department of Otolaryngology, Head and Neck Surgery, University of Tubingen, Germany
    Diagn Pathol 6:94. 2011
  3. doi Diagnostic accuracy of fine-needle aspiration cytology in Warthin tumors
    Laura L Veder
    Department of Otorhinolaryngology Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Head Neck 32:1635-40. 2010
  4. ncbi Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases
    F A Ito
    Semiology and Oral Pathology, Dental School, University of Campinas, Piracicaba, SP, Brazil
    Int J Oral Maxillofac Surg 34:533-6. 2005
  5. doi Salivary gland tumors: a single institution experience in India
    Krishnaraj Subhashraj
    Department of Oral and Maxillofacial Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    Br J Oral Maxillofac Surg 46:635-8. 2008
  6. ncbi Significance of clinical stage, extent of surgery, and pathologic findings in metastatic cutaneous squamous carcinoma of the parotid gland
    Christopher J O'Brien
    Department of Head and Neck Surgery, Royal Prince Alfred Medical Centre, 100 Carillon Avenue, Newtown NSW, Australia 2042
    Head Neck 24:417-22. 2002
  7. doi Salivary duct carcinoma in situ of the parotid gland
    R H W Simpson
    Department of Histopathology, Royal Devon and Exeter Hospital, Exeter, UK
    Histopathology 53:416-25. 2008
  8. ncbi Tissue that has lost its track: Warthin's tumour
    A Teymoortash
    Department of Otolaryngology, Head and Neck Surgery, Philipps University, Deutschhausstr 3, 35037 Marburg, Germany
    Virchows Arch 446:585-8. 2005
  9. ncbi Carcinoma of the parotid and submandibular glands--a study of survival in 2465 patients
    Peter Wahlberg
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, S 221 85 Lund, Sweden
    Oral Oncol 38:706-13. 2002
  10. doi Parotid tumors: a 10-year experience
    Ching Chia Lin
    Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan
    Am J Otolaryngol 29:94-100. 2008

Research Grants

Detail Information

Publications214 found, 100 shown here

  1. pmc An invasive adenocarcinoma of the accessory parotid gland: a rare example developing from a low-grade cribriform cystadenocarcinoma?
    Shin ichi Nakatsuka
    Department of Pathology, Kansai Rosai Hospital, 3 1 69 Inabaso, Amagasaki, Hyogo 660 8511, Japan
    Diagn Pathol 6:122. 2011
    ..These histological findings suggest the possibility that ANOS might arise secondarily from LGCCA. This is an interesting case regarding the association between ANOS and LGCCA in oncogenesis...
  2. pmc Dendritic cell tumor in a salivary gland lymph node: a rare differential diagnosis of salivary gland neoplasms
    Sebastian P Schraven
    Department of Otolaryngology, Head and Neck Surgery, University of Tubingen, Germany
    Diagn Pathol 6:94. 2011
    ..Awareness that dendritic cell tumors may occur in this localization, careful histologic evaluation and ancillary immunohistochemical and electron microscopical analyses should allow for recognition of this entity...
  3. doi Diagnostic accuracy of fine-needle aspiration cytology in Warthin tumors
    Laura L Veder
    Department of Otorhinolaryngology Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Head Neck 32:1635-40. 2010
    ..Our aim was to evaluate the diagnostic accuracy of fine-needle aspiration cytology (FNAC) for Warthin tumors of the parotid gland...
  4. ncbi Salivary gland tumors in a Brazilian population: a retrospective study of 496 cases
    F A Ito
    Semiology and Oral Pathology, Dental School, University of Campinas, Piracicaba, SP, Brazil
    Int J Oral Maxillofac Surg 34:533-6. 2005
    ..Pleomorphic adenoma was the most frequent tumor representing 54.2% of all cases, followed by mucoepidermoid carcinoma (13.5%), Warthin's tumor (8.5%) and adenoid cystic carcinoma (7.9%)...
  5. doi Salivary gland tumors: a single institution experience in India
    Krishnaraj Subhashraj
    Department of Oral and Maxillofacial Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    Br J Oral Maxillofac Surg 46:635-8. 2008
    ..Demographic data from these studies should help us to a better understanding of the biological and clinical characteristics of the disease...
  6. ncbi Significance of clinical stage, extent of surgery, and pathologic findings in metastatic cutaneous squamous carcinoma of the parotid gland
    Christopher J O'Brien
    Department of Head and Neck Surgery, Royal Prince Alfred Medical Centre, 100 Carillon Avenue, Newtown NSW, Australia 2042
    Head Neck 24:417-22. 2002
    ....
  7. doi Salivary duct carcinoma in situ of the parotid gland
    R H W Simpson
    Department of Histopathology, Royal Devon and Exeter Hospital, Exeter, UK
    Histopathology 53:416-25. 2008
    ..To describe three cases of purely in situ salivary duct carcinoma, so as better to define the entity...
  8. ncbi Tissue that has lost its track: Warthin's tumour
    A Teymoortash
    Department of Otolaryngology, Head and Neck Surgery, Philipps University, Deutschhausstr 3, 35037 Marburg, Germany
    Virchows Arch 446:585-8. 2005
    ....
  9. ncbi Carcinoma of the parotid and submandibular glands--a study of survival in 2465 patients
    Peter Wahlberg
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, S 221 85 Lund, Sweden
    Oral Oncol 38:706-13. 2002
    ..Age and gender had an impact on relative survival for patients with mucoepidermoid carcinoma, adenocarcinoma and undifferentiated cancer of the parotid...
  10. doi Parotid tumors: a 10-year experience
    Ching Chia Lin
    Department of Otolaryngology, China Medical University Hospital, Taichung, Taiwan
    Am J Otolaryngol 29:94-100. 2008
    ..The aim of the present study was to analyze the clinical presentation, histopathology, and complications of parotid tumors, as well as the management of malignant parotid tumors...
  11. ncbi Incidence rates of salivary gland tumors: results from a population-based study
    J A Pinkston
    Department of Epidemiology, School of Public Health, University of Alabama at Birmingham, 35211, USA
    Otolaryngol Head Neck Surg 120:834-40. 1999
    ..05). Warthin's tumor was rare in black patients (P < 0.001). We conclude that salivary gland tumors are an uncommon but epidemiologically diverse group of tumors. Their causes are also likely to differ...
  12. doi Interdigitating dendritic cell sarcoma of the parotid gland: case report and literature review
    Guy Efune
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, TX 75390 9035, USA
    Am J Otolaryngol 30:264-8. 2009
    ..Awareness of this tumor and the use of appropriate markers are crucial in making the diagnosis. The patient did well postoperatively, and he underwent a complete course of postoperative irradiation to the right parotid and neck...
  13. ncbi Primary and metastatic cancer of the parotid: comparison of clinical behavior in 232 cases
    Luc P Bron
    Sydney Head and Neck Cancer Institute, Royal Prince Alfred Hospital, Australia
    Laryngoscope 113:1070-5. 2003
    ..The aim of the study was to compare the clinical behavior of primary and metastatic parotid cancers by analyzing patterns of treatment failure and clinical outcomes...
  14. doi Prognostic index for patients with parotid carcinoma: international external validation in a Belgian-German database
    Vincent Vander Poorten
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals, Leuven, Belgium
    Cancer 115:540-50. 2009
    ..Prognostic indices for recurrence-free interval in patients with parotid carcinoma were developed and validated in a nationwide database. International validation would increase generalizability...
  15. ncbi Unilateral, multicentric Warthin's tumor mimicking a tumor metastatic to a lymph node. A case report
    Seoung Wan Chae
    Department of Pathology, Kangbuk Samsung Hospital, College of Medicine, Sungkyunkwan University, Seoul, South Korea
    Acta Cytol 48:229-33. 2004
    ..We report a case of unilateral, multicentric Warthin's tumor arising in periparotid and intraparotid glands, leading to a strong clinical and cytologic suspicion of malignancy...
  16. ncbi Parotidectomy: review of treatment and outcomes
    Ronaldo Bova
    Department of Otolaryngology, Head and Neck Surgery, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
    ANZ J Surg 74:563-8. 2004
    ..Parotidectomy is a common surgical procedure performed for a wide array of benign and malignant tumours. The aim of the present study was to review a single-institution experience with parotidectomy over a 10 year period...
  17. ncbi Clinical features of cystadenolymphoma (Warthin's tumor) of the parotid gland: a retrospective comparative study of 96 cases
    A Teymoortash
    Department of Otolaryngology, Head and Neck Surgery, Philipps University, Deutschhaus Str 3, 35037 Marburg, Germany
    Oral Oncol 42:569-73. 2006
    ..Compared with never smokers, clearly higher odds of Warthin's tumor was observed in heavy smokers (more than 30 pack-years) (odds ratio=24.1, P<0.0001) than patients who smoked less than 30 pack-years (odds ratio=4.9, P<0.0001)...
  18. doi Recurrent cancer of the parotid gland: how well does salvage surgery work for locoregional failure?
    Kenya Kobayashi
    Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    ORL J Otorhinolaryngol Relat Spec 71:239-43. 2009
    ..Many articles have discussed the clinical features of previously untreated parotid cancer, but the clinical characteristics and treatment of recurrent parotid cancer have not yet been fully described...
  19. ncbi Extent of parotid disease influences outcome in patients with metastatic cutaneous squamous cell carcinoma
    Carsten E Palme
    Sydney Head and Neck Cancer Institute, Royal Prince Alfred Hospital, Australia
    Arch Otolaryngol Head Neck Surg 129:750-3. 2003
    ..To test a new clinical staging system in patients with metastatic cutaneous squamous cell carcinoma involving the parotid gland or lymph nodes of the neck...
  20. doi Sonoelastography techniques in the evaluation and diagnosis of parotid neoplasms
    Olwen Westerland
    Radiology Department, Eastbourne District General Hospital, Kings Drive, Eastbourne, East Sussex, BN21 2UD, UK
    Eur Radiol 22:966-9. 2012
    ....
  21. ncbi Metastatic cutaneous squamous cell carcinoma to the parotid: the role of surgery and adjuvant radiotherapy to achieve best outcome
    Eddy Dona
    Head and Neck Unit, Westmead Hospital, Sydney, New South Wales, Australia
    ANZ J Surg 73:692-6. 2003
    ..Parotidectomy +/- neck dissection followed by adjuvant radiotherapy should be considered as best practice...
  22. ncbi Primary and non-primary parotid malignancies: comparison of treatment modalities and outcomes
    Sylvain Moriniere
    Department of Otolaryngology, Head and Neck Surgery, Faculty of Medicine, University Francois Rabelais, Bretonneau Hospital, 4 Bd Tonnellé, 37044, Tours Cedex 1, France
    Eur Arch Otorhinolaryngol 264:1231-7. 2007
    Our aim was to report our experience in the management of malignant primary and non-primary parotid neoplasms and to compare the clinical presentations, the treatment modalities and the outcomes in these two groups...
  23. ncbi Multivariate prediction of the probability of recurrence in patients with carcinoma of the parotid gland
    Jose F Carrillo
    Head and Neck Department, Division of Surgery, Instituto Nacional de Cancerologia, Mexico City, Mexico
    Cancer 109:2043-51. 2007
    ..The objective of the current study was to identify prognostic factors in patients with parotid gland carcinoma and to develop a method for defining the probability of recurrence...
  24. ncbi Treatment of carcinoma of the parotid gland: the results of a multicenter study
    A Tullio
    Department of Maxillo-Facial Surgery, Hospital of Parma, Italy
    J Oral Maxillofac Surg 59:263-70. 2001
    ..CONCLUSIONS: Postoperative irradiation is indicated for patients with stage III and IV disease, patients with positive excision margins, and for patients with lymph node metastases...
  25. pmc Clinico-pathological and treatment-related factors influencing survival in parotid cancer
    A G Renehan
    Department of Surgery, Christie Hospital NHS Trust, Manchester, UK
    Br J Cancer 80:1296-300. 1999
    ..Post-operative RT contributes significantly to locoregional control and probably confers some survival advantage in high-risk patients...
  26. ncbi The indications for elective treatment of the neck in cancer of the major salivary glands
    J G Armstrong
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021
    Cancer 69:615-9. 1992
    ..High-grade tumors and larger tumors have a high rate of occult neck metastases, and treatment should be considered in this group...
  27. ncbi Parotid carcinoma: impact of clinical factors on prognosis in a histologically revised series
    Christian Godballe
    Department of Otolarynology Head and Neck Surgery, Odense University Hospital, Denmark
    Laryngoscope 113:1411-7. 2003
    ..To analyze clinical data and possible prognostic factors of patients with primary carcinoma of the parotid gland...
  28. ncbi Parotid gland carcinoma: 1987 and 1997 UICC T classifications compared for prognostic accuracy at 5 years
    F Carinci
    ENT Clinic, University of Ferrara, Arcispedale S. Anna, C.so Giovecca 203, 44100 Ferrara, Italy
    Eur Arch Otorhinolaryngol 258:150-4. 2001
    ..We conclude that the newer (1997) UICC T category better defines the prognosis for cancer of the parotid gland and should have a higher impact on the clinical evaluation of patients...
  29. ncbi Parotid neoplasms: analysis of 600 patients attended at a single institution
    Ademar Takahama Junior
    Faculdade de Odontologia de Piracicaba, Universidade Estadual de Campinas, Brazil
    Braz J Otorhinolaryngol 75:497-501. 2009
    ..Salivary gland tumors are rare, generally benign and affect mainly the parotid gland...
  30. ncbi Randomized clinical trial comparing partial parotidectomy versus superficial or total parotidectomy
    J L Roh
    Department of Otolaryngology, Asan Medical Centre, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736, Korea
    Br J Surg 94:1081-7. 2007
    ..This study examined whether current surgical techniques improved functional outcomes after surgery for benign parotid tumours...
  31. ncbi Malignant parotid tumors: presentation, clinical/pathologic prognostic factors, and treatment outcomes
    Surjeet Pohar
    Department of Radiation Oncology, State University of New York Upstate Medical University, Syracuse, NY 13210, USA
    Int J Radiat Oncol Biol Phys 61:112-8. 2005
    ..To determine the important clinical/pathologic prognostic factors and optimal treatment of malignant parotid tumors...
  32. ncbi Evidence of lymphangiogenesis in Warthin's tumor of the parotid gland
    A Teymoortash
    Department of Otolaryngology, Head and Neck Surgery, Philipp University, Deutschhausstr 3, 35037 Marburg, Germany
    Oral Oncol 43:614-8. 2007
    ..0001 versus P<0.004). The increase in lymphatic vessels in Warthin's tumor suggests that epithelial tumor cells might promote lymphangiogenesis in this kind of lesions...
  33. ncbi Synchronous parotid and nasopharyngeal Warthin's tumors: first report of a case
    Wong Kein Low
    Department of Otolaryngology, Singapore General Hospital, Singapore 169608
    Ear Nose Throat J 81:839-41. 2002
    ..Their simultaneous presence might have been more than coincidental; it is possible that these two tumors were the result of the influence of one or more unknown systemic factors on trapped salivary elements in the lymphoid stroma...
  34. ncbi Facial nerve function in carcinoma of the parotid gland
    Chris Terhaard
    Department of Radiotherapy, University Medical Center, UMC Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Eur J Cancer 42:2744-50. 2006
    ..To analyse, for patients with carcinoma of the parotid gland, the prognostic value for treatment outcome of the function of the facial nerve (NVII), and determining facial nerve dysfunction after treatment...
  35. ncbi Malignant parotid tumor and facial palsy
    Chun Chi Huang
    Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan
    Otolaryngol Head Neck Surg 136:778-82. 2007
    ..To evaluate risk factors for postoperative facial palsy in patients with parotid carcinoma...
  36. ncbi Oncocytic carcinoma arising in Warthin tumour
    Maria P Foschini
    Virchows Arch 446:88-90. 2005
  37. ncbi Prognostic indicators for malignant tumours of the parotid gland
    G Harbo
    ENT Department, Aarhus University Hospital, Aarhus, Denmark
    Clin Otolaryngol Allied Sci 27:512-6. 2002
    ..03). The TNM system is a good predictor of treatment outcome for malignant parotid tumours. The use of a combination of clinical and histological factors will assist the design of treatment strategies for parotid gland tumours...
  38. doi Predicting facial nerve invasion by parotid gland carcinoma and outcome of facial reanimation
    M Preis
    Department of Otolaryngology and Head and Neck Surgery, Rabin Medical Center, Beilinson Campus, 49100 Petach Tikva, Israel
    Eur Arch Otorhinolaryngol 267:107-11. 2010
    ..Deep lobe involvement and large tumor size may identify patients at risk of facial nerve involvement. Reanimation is associated with good functional outcome regardless of patient's age...
  39. ncbi Malignant salivary gland tumours in Sweden 1960-1989--an epidemiological study
    J Ostman
    Department of Oral Pathology, Umea University, Sweden
    Oral Oncol 33:169-76. 1997
    ....
  40. ncbi Preoperative cytology in the management of parotid neoplasms
    Salvatore Aversa
    Department of Otolaryngology, University of Turin, San Luigi Hospital, Orbassano, Torino, Italy
    Am J Otolaryngol 27:96-100. 2006
    This study evaluates the diagnostic role of preoperative cytology of parotid neoplasms. The method is particularly useful in the evaluation of the parotid diseases in which the same clinical features may be treated variously...
  41. ncbi The value of dynamic MRI studies in parotid tumors
    Sedat Alibek
    Institute of Radiology, University of Erlangen Nuremberg, Maximiliansplatz 1 91054 Erlangen, Germany
    Acad Radiol 14:701-10. 2007
    ..To evaluate the ability of dynamic contrast-enhanced magnetic resonance imaging (MRI) to differentiate several tumor entities of the parotid gland in a prospective clinical trial...
  42. ncbi Mucoepidermoid carcinoma of the major salivary glands: clinical and histopathologic analysis of 234 cases with evaluation of grading criteria
    R K Goode
    Department of Oral and Maxillofacial Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Cancer 82:1217-24. 1998
    ..The current study investigated the usefulness of these features in determining the prognoses of patients with mucoepidermoid carcinomas of the major salivary glands...
  43. ncbi Superficial parotidectomy via facelift incision
    Peter J F M Lohuis
    Department of Head and Neck Oncology and Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Ann Otol Rhinol Laryngol 118:276-80. 2009
    ..It can be offered as an alternative to a select group of patients who present with a small, mobile tumor in the tail of the parotid gland and an explicit request for an invisible postoperative scar...
  44. ncbi Reconstruction of complex parotidectomy defects using the lateral arm free tissue transfer
    Theodoros N Teknos
    Department of Otolaryngology, University of Michigan Health System, Ann Arbor, MI 48109 0312, USA
    Otolaryngol Head Neck Surg 129:183-91. 2003
    ..The posterior cutaneous nerve of the forearm (PCNF) was used as a facial nerve cable graft in 14 patients. Facial disability outcomes were measured using the Facial Clinimetric Evaluation scale...
  45. ncbi Dynamic multislice computed tomography findings for parotid gland tumors
    Hasan Yerli
    Department of Radiology, Baskent University Medical School, Ankara, Turkey
    J Comput Assist Tomogr 31:309-16. 2007
    ..Our aim was to research the enhancement features of parotid gland masses in detail and characterize if the masses were Warthin tumors, adenomas, or malignant tumors...
  46. doi Synovial sarcoma presenting as a parotid mass: case report and review of literature
    Amrita Jay
    Department of Histopathology, Barts and The London NHS Trust, Whitechapel, London, United Kingdom
    Head Neck 30:1654-9. 2008
    ..Synovial sarcoma is an unusual neoplasm of mesenchymal derivation, which is uncommon in the head and neck sites. In the parotid gland, it is most likely to be misdiagnosed as a myoepithelial, primary mesenchymal, or metastatic neoplasm...
  47. ncbi Sternocleidomastoid muscle flap reconstruction during parotidectomy to prevent Frey's syndrome and facial contour deformity
    Korhan Asal
    Department of Otorhinolaryngology Head and Neck Surgery, Gazi University Hospital, Ankara, Turkey
    Ear Nose Throat J 84:173-6. 2005
    ..The difference between the two groups was statistically significant (p < 0.05). No statistically significant difference was seen between the two groups with respect to cosmetic results...
  48. ncbi [Malignant fibrous histiocytoma in the parotid gland. Case series and literature review]
    F Sachse
    Klinik und Poliklinik Fur Hals, Nasen und Ohrenkrankheiten, Universitatsklinikum Munster
    HNO 54:116-20. 2006
    ..This study presents the clinicopathological features of three patients with MFH of the parotid gland treated at the ENT department of the University Hospital of Muenster (Germany) between 1991 and 2002...
  49. doi Low-grade cribriform cystadenocarcinoma of the parotid gland: a case report
    Akihito Arai
    Department of Otolaryngology, Kyoto Prefectural University of Medicine, 465 Kajii cho, Kawaramachi Hirokoji, Kamigyo ku, Kyoto City, Kyoto 602 0841, Japan
    Auris Nasus Larynx 36:725-8. 2009
    ..Immunohistochemically, smooth muscle actin highlighted the cells rimming the cystic spaces. The tumor cells were negative for S-100 protein. The patient has no recurrence and no facial palsy after the treatment...
  50. ncbi Warthin tumor of the parotid gland: diagnostic value of MR imaging with histopathologic correlation
    Mitsuaki Ikeda
    Department of Radiology, Chiba University Hospital, Chiba, Japan
    AJNR Am J Neuroradiol 25:1256-62. 2004
    ..The purpose of our study was to describe the MR imaging appearance of Warthin tumors multiple MR imaging techniques and to interpret the difference in appearance from that of malignant parotid tumors...
  51. doi Oncocytic carcinoma of the accessory lobe of the parotid gland
    Giuseppe Colella
    Department of Head and Neck Surgery, Second University of Naples, Naples, Italy
    J Craniofac Surg 21:1987-90. 2010
    ..The clinical and histologic difficulties in relationship to the diagnosis of a midcheek mass consisting of an unusual tumor are emphasized...
  52. ncbi Tumors of the accessory lobe of the parotid gland: a 10-year experience
    Derrick T Lin
    Vanderbilt University Medical Center, Department of Otolaryngology, Nashville, TN, USA
    Laryngoscope 114:1652-5. 2004
    ..We report our 10-year experience with the diagnosis and treatment of eight accessory parotid gland neoplasms that have been followed by the senior authors...
  53. ncbi Distant metastasis of parotid gland tumors
    Ilona Schwentner
    Department of Otorhinolaryngology, Medical University Innsbruck, Austria
    Acta Otolaryngol 126:340-5. 2006
    ..On the basis of a clinical case regarding a patient with metastatic parotid gland cancer we present a review of the literature...
  54. doi Cytological features of cystadenocarcinoma in cyst fluid of the parotid gland: Diagnostic pitfalls and literature review
    Akihiko Kawahara
    Department of Diagnostic Pathology, Kurume University Hospital, Kurume 19107, Japan
    Diagn Cytopathol 38:377-81. 2010
    ....
  55. ncbi Face-lift approach combined with a superficial musculoaponeurotic system advancement flap in parotidectomy
    Andreas Foustanos
    Plastic Surgery Department, IASO Hospital, 37 39 Kifisias Avenue, 151 23 Maroussi, Athens, Greece
    Br J Oral Maxillofac Surg 45:652-5. 2007
    ..All patients were satisfied with the cosmetic outcome, and the depression deformity was considerably less. This approach prevented gustatory sweating. We think that this approach is simple and a useful tool in parotidectomy...
  56. doi Low-grade cribriform cystadenocarcinoma of the parotid gland: a neoplasm with favorable prognosis, distinct from salivary duct carcinoma
    Jan Laco
    The Fingerland Department of Pathology, Charles University Faculty of Medicine and Faculty Hospital in Hradec Kralove, Czech Republic
    Int J Surg Pathol 18:369-73. 2010
    ..The patient is free of disease for 2 years. The relationship between low-grade cribriform cystadenocarcinoma and salivary duct carcinoma is discussed...
  57. ncbi True malignant mixed tumor (carcinosarcoma) of parotid gland with unusual mesenchymal component: a case report and review of the literature
    M Y Kwon
    Department of Pathology, University of California Irvine Medical Center, Orange, CA 92868, USA
    Arch Pathol Lab Med 125:812-5. 2001
    ..In addition, the literature is reviewed, and the possible histogenesis and pathogenesis of malignant mixed tumor of the salivary gland are briefly discussed...
  58. ncbi Stereotactic radiosurgery for recurrent pleomorphic adenoma invading the skull base--case report--
    Tohru Kamida
    Department of Neurosurgery, Oita University Faculty of Medicine
    Neurol Med Chir (Tokyo) 45:161-3. 2005
    ..The symptoms were reduced within a few months. Magnetic resonance imaging over 5 years showed that the tumor was controlled with no regrowth. Stereotactic radiotherapy is a therapeutic option for the treatment of pleomorphic adenomas...
  59. ncbi Hemangiopericytoma of the parotid gland: a case report
    Fatih Oktem
    Department of Otolaryngology, Cerrahpaşa Medicine Faculty of İstanbul University, Istanbul, Turkey
    Kulak Burun Bogaz Ihtis Derg 17:112-5. 2007
    ..Superficial parotidectomy was performed. Histopathological diagnosis was made as hemangiopericytoma. No evidence for local recurrence or distant metastasis was seen within a follow-up of 36 months...
  60. ncbi Recurrent pleomorphic adenoma of the parotid gland
    Evelyn Linda Maxwell
    Department of Otolaryngology Head Neck Surgery, University of Toronto, Mount Sinai Hospital, Toronto, ON
    J Otolaryngol 33:181-4. 2004
    ..We experienced a locoregional control rate of 77%. Our malignant transformation rate was 5.7%. Our results suggest that in carefully selected patients, local excision of recurrent disease is sufficient in controlling further recurrence...
  61. ncbi Recurrent pleomorphic adenoma of the parotid gland: analysis of 108 consecutive patients
    Claus Wittekindt
    Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, D 50924 Cologne, Germany
    Head Neck 29:822-8. 2007
    ..Surgery for recurrent parotid pleomorphic adenoma is a challenging problem...
  62. doi Sclerosing rhabdomyosarcoma of the parotid gland in an adult
    Janez Lamovec
    Institute of Oncology, Department of Pathology, 1000 Ljubljana, Slovenia
    Ann Diagn Pathol 13:334-8. 2009
    ..To our knowledge, this is the first reported case of primary sclerosing rhabdomyosarcoma of the parotid gland...
  63. ncbi Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report
    Alexander Delides
    Department of Otolaryngology, Athens Medical Center, Distomou 5 7, Marousi, 151 25 Athens, Greece
    Head Neck 27:825-8. 2005
    ..Acinic cell carcinoma is a common neoplasm of the salivary glands that occurs predominately in the parotid. Only one case of a familial recurrence of such a neoplasm and 16 cases of bilateral tumors have been reported...
  64. ncbi Increased expression of cyclooxygenase-2 and Ki-67 are associated with malignant transformation of pleomorphic adenoma
    Hideaki Katori
    Department of Otolaryngology, Yokohama City Minato Red Cross Hospital, 3 12 1 Shin Yamashita, Naka ku, Yokohama 231 8682, Japan
    Auris Nasus Larynx 34:79-84. 2007
    ..We also aimed to relate the overexpression of COX-2 with the pathways of malignant transformation of Ca ex-PA as evidenced by distinct morphological features...
  65. ncbi High risk for bilateral Warthin tumor in heavy smokers--review of 185 cases
    Jens Peter Klussmann
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University of Cologne, Cologne, Germany
    Acta Otolaryngol 126:1213-7. 2006
    ..We identified smoking as a significant risk factor for multilocular Warthin tumor development. Therefore, we recommend taking history of smoking into account when making the decisions for surgical strategy...
  66. ncbi Unusual localization of an adenoid cystic carcinoma subsequent to superficial parotidectomy for a benign lesion
    Argyrios Manganaris
    E N T Department, Theagenio Anticancer Hospital, 2 Alexandrou Simeonidi Str, Thessaloniki Greece
    J Craniofac Surg 18:231-5. 2007
    ..The management of this case is presented along with a brief review of the literature concerning the evaluation and management of this rare entity...
  67. ncbi Metachronous bilateral pleomorphic adenoma of the parotid gland
    Sindeval José da Silva
    Department of Head and Neck Surgery, University Hospital, School of Medicine, Federal University of Uberlandia, Uberlandia, MG, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:333-8. 2006
    ..Only on the left side some facial nerve branches were removed that induced partial paralysis in the patient. A review of the pertinent literature is included...
  68. ncbi Recurrent pleomorphic adenoma of the parotid gland in pediatric and adult patients: value of multiple lesions as a diagnostic indicator
    Korgun Koral
    Department of Radiological Sciences, Center for the Health Sciences, UCLA School of Medicine, 650 Charles E Young Dr, S, Los Angeles, CA 90095, USA
    AJR Am J Roentgenol 180:1171-4. 2003
    ..Our aim was to analyze the imaging of a series of patients to determine the reliability of multiple lesions as a tool in diagnosing recurrent disease...
  69. ncbi Multiple synchronous and metachronous neoplasms of the parotid gland: the Chichester experience
    M Ethunandan
    Maxillofacial Unit, St Richard s Hospital, Chichester, West Sussex, UK
    Br J Oral Maxillofac Surg 44:397-401. 2006
    b>Parotid neoplasms are usually solitary and multiple tumours occurring in an individual are uncommon. The incidence and implications of multiple synchronous and metachronous tumours remains relatively unknown...
  70. ncbi Bilateral intraparotid and extraparotid Warthin's tumours
    N Shah
    Department of Oral and Maxillofacial Surgery, Queen Victoria Hospital, Holtye Road, East Grinstead, West Sussex RH19 3DZ, UK
    Br J Oral Maxillofac Surg 45:238-9. 2007
    ..In this report, we describe a patient with simultaneous bilateral involvement of the parotid glands and neck by multiple Warthin's tumours, an occurrence not previously described...
  71. ncbi Recurrent pleomorphic adenoma of the parotid gland
    John P Leonetti
    Loyola Center for Cranial Base Surgery, Maywood, IL 60153, USA
    Otolaryngol Head Neck Surg 133:319-22. 2005
    ..To assess the long-term results in the management of 42 patients with recurrent pleomorphic adenoma of the parotid gland...
  72. ncbi Recurrent benign parotid tumours: the lesson not learnt yet?
    N Patel
    Department of Head and Neck Surgery, Royal North Shore Hospital, Sydney, New South Wales, Australia
    Aust N Z J Surg 68:562-4. 1998
    ..To study the behaviour of recurrent benign parotid tumours, recurrence characteristics and problems faced with the removal of these lesions...
  73. pmc Translocation, deletion/amplification, and expression of HMGIC and MDM2 in a carcinoma ex pleomorphic adenoma
    Eva Roijer
    Lundberg Laboratory for Cancer Research, Department of Pathology, Goteborg University, Sahlgrenska University Hospital, SE 413 45 Goteborg, Sweden
    Am J Pathol 160:433-40. 2002
    ..These findings suggest that amplification and overexpression of HMGIC and possibly MDM2 might be important genetic events that may contribute to malignant transformation of benign PA...
  74. ncbi Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature
    Jonathan L Curry
    Department of Pathology, Loyola University Medical Center, Loyola University Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA
    Head Neck 24:301-6. 2002
    ..3% of all salivary gland neoplasms. Only nine cases of synchronous benign and malignant ipsilateral parotid gland tumors have been described in the literature...
  75. ncbi Epithelial-myoepithelial carcinoma of the parotid gland
    Masaki Kumagai
    Department of Otolaryngology, Sendai National Hospital, 2 8 8 Miyagino, Miyagino ku, Japan
    Auris Nasus Larynx 30:201-3. 2003
    ..His post-operative course was uneventful, and he is currently free from disease 6 months after surgery. Diagnosis, clinical behavior and treatment of EMC are reviewed from perusal of the literature...
  76. doi Multifocal multi-site Warthin tumour
    Jennifer M Hilton
    Department of Otolaryngology Head and Neck Surgery, James Paget University Hospital, Great Yarmouth, Norfolk, NR31 6LA, UK
    Eur Arch Otorhinolaryngol 265:1573-5. 2008
    ..The presented case is unique in having synchronous and metachronous Warthin tumours, as well as one of the tumours being neither truly parotid, nor within a lymph node...
  77. ncbi Histopathology of pleomorphic adenoma in the parotid gland: a prospective unselected series of 100 cases
    E Stennert
    Department of Otorhinolaryngology, University of Cologne, Koeln, Germany
    Laryngoscope 111:2195-200. 2001
    ....
  78. doi Primary synovial sarcoma arising in the parotid region diagnosed by fluorescence in situ hybridization
    Ryo Kawata
    Department of Otolaryngology, Osaka Medical College, 2 7 Daigaku Cho Takatsuki, Osaka 569 8686, Japan
    Auris Nasus Larynx 35:583-6. 2008
    ..The stromal cells were immunoreactive for vimentin and BCL2. The both types of cells were positive for CD99. The SYT-SSX fusion gene from chromosomal translocation was detected by fluorescence in situ hybridization in this case...
  79. ncbi Synchronous bilateral mucoepidermoid carcinoma of the parotid gland
    Nobuhiro Hakuba
    Department of Otolaryngology, Ehime University School of Medicine, Onsen gun Ehime, Japan
    J Laryngol Otol 117:419-21. 2003
    ..A case of bilateral facial nerve dysfunction is presented in which aggressive surgery failed to save the life of a 48-year-old man. This is the first such case reported in the available English literature...
  80. ncbi Recurrent pleomorphic adenoma of the parotid gland: a prospective histopathological and immunohistochemical study
    Eberhard Stennert
    Department of Otolaryngology Head and Neck Surgery, University of Cologne, Koeln, Germany
    Laryngoscope 114:158-63. 2004
    ..Histopathological characteristics and proliferation indices of recurrent pleomorphic adenoma were described in a series of 31 patients who were referred to the authors' clinic for revision surgery...
  81. ncbi Metastatic neuroendocrine tumors of the parotid gland
    Allison T Pontius
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center at Dallas, Dallas, USA
    Am J Otolaryngol 25:129-33. 2004
    ..To present 2 cases of neuroendocrine tumors of the parotid gland and to review the clinical presentation, histopathologic, and immunohistochemical findings and treatment of these rare tumors...
  82. ncbi Pleomorphic adenoma with extensive adenoid cystic carcinoma-like cribriform areas of parotid gland
    Ikuko Ogawa
    Clinical Laboratory, Hiroshima University Dental Hospital, Hiroshima University, Japan
    Pathol Int 53:30-4. 2003
    ..In addition, the low proliferative activity observed in the entire tumor suggested that the cribriform nests resembling ACC are also the component of PA...
  83. ncbi Carcinosarcoma of the parotid gland: report of a case with immunohistochemical findings
    Benjamin D Liess
    Department of Otolaryngology Head and Neck Surgery, University of Missouri School of Medicine, Columbia, MO 65212, USA
    Ann Otol Rhinol Laryngol 116:702-4. 2007
    ..An understanding of this manifestation is crucial to guide management and treatment of this disease...
  84. ncbi Warthin's tumour: a study of 78 cases with emphasis on bilaterality, multifocality and association with other malignancies
    E Maiorano
    Department of Pathological Anatomy and Genetics, Section of Pathological Anatomy, University of Bari, Policlinico, Piazza G Cesare 11, 70124 Bari, Italy
    Oral Oncol 38:35-40. 2002
    ..These usually consist in (bilateral) superficial parotidectomy and should be followed by long term follow up of the patients, in view of possible metachronous WTs, even after prolonged time intervals...
  85. ncbi Hemangiopericytoma of the parotid gland: CT and MR features
    B Mortele
    Department of Radiology, Gent University Hospital, De Pintelaan 185, 9000 Gent, Belgium
    Eur Radiol 11:1073-5. 2001
    ..A case of hemangiopericytoma of the parotid gland is presented. The clinical, surgical, histologic, and radiologic features are described and discussed...
  86. ncbi Surgical treatment of recurrences of pleomorphic adenoma of the parotid gland
    R Becelli
    Dept. of Maxillo Facial Surgery, University of Rome La Sapienza, Rome, Italy
    J Exp Clin Cancer Res 20:487-9. 2001
    ..Finally, tumour control rates and facial nerve preservation are enhanced with formal parotidectomy for recurrent tumour when feasible...
  87. ncbi The significance of the margin in parotid surgery for pleomorphic adenoma
    Robert L Witt
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, Christiana Care Health Systems, Newark, Delaware, USA
    Laryngoscope 112:2141-54. 2002
    ....
  88. ncbi Expression profiles of p53, p63, and p73 in benign salivary gland tumors
    Anette Weber
    Department of Oto Rhino Laryngology, Head and Neck Surgery, University of Leipzig, Germany
    Virchows Arch 441:428-36. 2002
    ..The prevalence of p53 mutations and the observation of the expression of DeltaNp63 isoforms only in pleomorphic adenomas, myoepitheliomas, and also basal cell adenomas may reflect their possible malignant potential...
  89. doi Carcinoma ex pleomorphic adenoma: diagnostic difficulty and outcome
    Peter Zbären
    Department of Otorhinolaryngology, Head, and Neck Surgery, University Hospital, Berne, Switzerland
    Otolaryngol Head Neck Surg 138:601-5. 2008
    ..To analyze a series of carcinoma ex pleomorphic adenoma (CXPA) and to assess the diagnostic difficulties...
  90. ncbi Multiple primary tumours of the parotid gland
    G Y Yu
    Center for Salivary Gland Diseases, Peking University School of Stomatology, Beijing 100081, China
    Int J Oral Maxillofac Surg 33:531-4. 2004
    ..B-mode ultrasound is the technique of choice for the screening of MPT. Meticulous intraoperative inspection and palpation of the glandular tissues and periglandular lymph nodes are necessary...
  91. ncbi Solitary fibrous tumor of the parotid gland: a case report
    Mario Fernando Muñoz Guerra
    University Hospital La Princesa, C General Ricardos n 171, 2 B, 28025 Madrid, Spain
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 94:78-82. 2002
    ..One year after excision, the patient was alive and without evidence of disease...
  92. ncbi [Recurrent benign tumors of parotid gland: the role of the surgery]
    G Mercante
    Clinica Otorinolaringoiatrica e Patologia Cervico Facciale, Universita di Parma
    Acta Otorhinolaryngol Ital 22:80-5. 2002
    ..The results of our study show that total parotidectomy should be the treatment of choice in case of benign parotid gland tumors and in particular for pleomorphic adenoma...
  93. ncbi MRI findings of carcinosarcoma in the parotid gland
    Kathleen F M Fan
    Department of Oral and Maxillofacial Surgery, Kent and Canterbury Hospital, Ethelbert Road, Canterbury, Kent CT1 3NG, UK
    Oral Oncol 42:323-6. 2006
    ..We present magnetic resonance imaging (MRI) findings of this tumour. MRI demonstrated heterogenous intermediate T2-W signal with a thick irregular enhancing rim was suggestive of a malignant lesion...
  94. ncbi Cutaneous metastasis from adenoid cystic carcinoma of the parotid gland
    Ching Hao Chang
    Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Dermatol Surg 29:775-9. 2003
    ..Cutaneous metastasis from adenoid cystic carcinoma of the salivary gland is very rare...
  95. ncbi Primary large-cell neuroendocrine carcinoma of the parotid gland: immunohistochemical and molecular analysis of two cases
    T Nagao
    Department of Surgical Pathology, Teikyo University, School of Medicine, Ichihara Hospital, Chiba, Japan
    Mod Pathol 13:554-61. 2000
    ..Multiple alterations of cell cycle regulators and tumor suppressor genes may play an important role in presenting the biologic characteristics of this rare parotid gland tumor...
  96. ncbi Surgical treatment of recurrent pleomorphic adenoma of the parotid gland: a clinical analysis of 52 patients
    A S Glas
    Department of Surgical Oncology/Head and Neck Surgery, University Hospital, Groningen, P.O. Box 30.001, 9700RB The Netherlands
    Head Neck 23:311-6. 2001
    ..The risk of new relapse and N.VII injury was higher after previous parotidectomy...
  97. ncbi Dermatopathic lymphadenitis of the head and neck
    Leslie K Winter
    Department of Otolaryngology Head and Neck Surgery, Boston University School of Medicine, Boston, MA, USA
    J Cutan Pathol 34:195-7. 2007
    ..While considered a benign histopathologic finding, differentiation of this disorder from mycosis fungoides or lymphoma can be difficult...
  98. ncbi Schwannomalike mixed tumor of the parotid gland: a case report
    Maciej Kajor
    Department of Pathomorphology and Laryngology Clinic, Medical University of Silesia, Katowice Poland
    Acta Cytol 50:529-30. 2006
    ..Schwannomalike mixed tumor is a rare benign tumor of the parotid glands...
  99. ncbi Differentiation of benign and malignant parotid tumors using deconvolution-based perfusion CT imaging: feasibility of the method and initial results
    S Bisdas
    Department of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Hospital, Frankfurt, Germany
    Eur J Radiol 64:258-65. 2007
    ..We evaluated the feasibility of perfusion CT (CTP) of the parotid gland and attempted to differentiate benign from malignant tumors...
  100. ncbi [Fine needle aspiration in salivary gland tumors: specificity and sensitivity]
    Antonio Jose Gonçalves
    Departamento de Cirurgia da Faculdade de Ciências Médicas da Santa Casa de São Paulo, Rua Dr Cesário Mota Júnior 112, Vila Buarque, CEP 01221 020 São Paulo, SP, Brazil
    Rev Assoc Med Bras 53:267-71. 2007
    ..As such, knowledge of correct cytological findings prior to surgery is important for therapeutic planning. This is not easily established since it is usually based only on the patients' clinical history and imaging exams..
  101. doi 125I seed implant brachytherapy-assisted surgery with preservation of the facial nerve for treatment of malignant parotid gland tumors
    J Zhang
    Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Hai Dian District, Beijing, PR China
    Int J Oral Maxillofac Surg 37:515-20. 2008
    ..A limited surgical resection combined with (125)I seed implant brachytherapy is therefore considered to be an alternative treatment for local control of malignant parotid gland tumors with preservation of the facial nerve...

Research Grants5

  1. Spatial-Temporal Imaging of Cell Proliferation & Hypoxia
    Robert Jeraj; Fiscal Year: 2007
    ....
  2. Dose painting based on hypoxia and proliferative response
    Robert Jeraj; Fiscal Year: 2010
    ..This approach will revolutionize the way that radiotherapy is prescribed and planned, and will improve the therapeutic outcome in terms of local tumor control and side-effects to unaffected tissue. ..