Genomes and Genes
Summary: A cutaneous disorder primarily of convexities of the central part of the FACE, such as FOREHEAD; CHEEK; NOSE; and CHIN. It is characterized by FLUSHING; ERYTHEMA; EDEMA; RHINOPHYMA; papules; and ocular symptoms. It may occur at any age but typically after age 30. There are various subtypes of rosacea: erythematotelangiectatic, papulopustular, phymatous, and ocular (National Rosacea Society's Expert Committee on the Classification and Staging of Rosacea, J Am Acad Dermatol 2002; 46:584-7).
Publications269 found, 100 shown here
- Rosacea: I. Etiology, pathogenesis, and subtype classificationGlen H Crawford
Department of Dermatology, University of Pennsylvania Medical Center, USA
J Am Acad Dermatol 51:327-41; quiz 342-4. 2004b>Rosacea is one of the most common conditions dermatologists treat. Rosacea is most often characterized by transient or persistent central facial erythema, visible blood vessels, and often papules and pustules...
- Therapeutic response of rosacea to dobesilatePedro Cuevas
Department of Research, Hospital Ramon y Cajal, Madrid, Spain
Eur J Med Res 10:454-6. 2005Despite an incomplete understanding of the pathogenesis of rosacea, therapeutic modalities continue to expand...
- Mite-related bacterial antigens stimulate inflammatory cells in rosaceaN Lacey
Department of Biology, National University of Ireland, Maynooth, Co Kildare, Ireland
Br J Dermatol 157:474-81. 2007Patients with papulopustular rosacea have a higher density of Demodex folliculorum mites on their faces than normal subjects but the role, if any, of their mites in initiating inflammation is disputed...
- Increased density of Demodex folliculorum and evidence of delayed hypersensitivity reaction in subjects with papulopustular rosaceaS Georgala
National University of Athens, Department of Dermatology and Venereology, A. Sygros' Hospital, Greece
J Eur Acad Dermatol Venereol 15:441-4. 2001BACKGROUND: Rosacea is a common chronic dermatosis that evolves in stages. The mite Demodex folliculorum has been implicated in its obscure aetiopathogenesis. AIM: To evaluate the importance of D...
- The molecular pathology of rosaceaKenshi Yamasaki
Division of Dermatology, University of California, San Diego, CA 92161, USA
J Dermatol Sci 55:77-81. 2009b>Rosacea is a common and chronic inflammatory skin disease that affects over 10 million Americans. Although the phenotypes of rosacea are clinically heterogeneous, they are all related by the presence of chronic facial skin inflammation...
- Topical kinetin 0.1% lotion for improving the signs and symptoms of rosaceaJ J Wu
Department of Dermatology, University of California, Irvine, Irvine, CA 92697 2400, USA
Clin Exp Dermatol 32:693-5. 2007Many patients with rosacea are unable to tolerate extended treatment periods with topical agents because of the unusually high skin sensitivity that often accompanies rosacea...
- Clinical practice. RosaceaFrank C Powell
Regional Centre of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland
N Engl J Med 352:793-803. 2005
- Recently approved systemic therapies for acne vulgaris and rosaceaJames Q Del Rosso
University of Nevada School of Medicine, Las Vegas, USA
Cutis 80:113-20. 2007..oral isotretinoin for the treatment of severe recalcitrant nodular acne, systemic therapy for acne vulgaris and rosacea has been based on anecdotal support, clinical experience, and small clinical trials...
- Papulopustular rosacea: prevalence and relationship to photodamageMaeve A McAleer
Regional Center of Dermatology, Mater Misericordiae University Hospital, Dublin, Ireland
J Am Acad Dermatol 63:33-9. 2010The prevalence and pathogenesis of rosacea is uncertain. Previously, studies used varying definitions of disease and have not explored the relationship of its prevalence to ultraviolet (UV) exposure or photodamage.
- [Concentration of selected cytokines in serum of patients with acne rosacea]Małgorzata Salamon
Katedra i Klinika Dermatologii i Wenerologii, Uniwersytetu Medycznego w Łodzi
Przegl Lek 65:371-4. 2008b>Rosacea is a common chronic disorder, mainly affects women in their thirties or fourties. As etiology, inflammation is taken into consideration.
- Photographic review of results from a clinical study comparing benzoyl peroxide 5%/clindamycin 1% topical gel with vehicle in the treatment of rosaceaJames J Leyden
Skin Study Center, Broomall, Pennsylvania, USA
Cutis 73:11-7. 2004..efficacy of topical benzoyl peroxide 5%/clindamycin 1% (BP/C) gel (BenzaClin) versus vehicle in the treatment of rosacea. The objective was to compare the baseline and end-of-treatment photographs of patients treated with BP/C versus ..
- Standard grading system for rosacea: report of the National Rosacea Society Expert Committee on the classification and staging of rosaceaJonathan Wilkin
Division of Dermatologic and Dental Drug Products, Food and Drug Administration, Rochville, Maryland, USA
J Am Acad Dermatol 50:907-12. 2004
- The metabolism and pharmacokinetics of isotretinoin in patients with acne and rosacea are not influenced by ethanolF Grønhøj Larsen
Department of Dermatology, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
Br J Dermatol 161:664-70. 2009Isotretinoin is effective in the treatment of severe acne and rosacea. Both parent drug and its main metabolite 4-oxo-isotretinoin are potentially teratogenic compounds and contain a carboxylic acid moiety...
- Comparison of tear function tests and impression cytology with the ocular findings in acne rosaceaV Yaylali
Department of Ophthalmology, Pamukkale University School of Medicine, Denizli, Turkey
Eur J Ophthalmol 12:11-7. 2002The aim of this study was to determine the correlation between tear function tests and impression cytology results and the clinical findings in ocular rosacea.
- Treatment of rosacea with intense pulsed light: significant improvement and long-lasting resultsP Papageorgiou
Department of Dermatology, Royal Free Hampstead NHS Trust, London NW3 2QG, UK
Br J Dermatol 159:628-32. 2008b>Rosacea is a common skin condition but the treatments currently available are not satisfactory.
- Rhinophyma: review and updateRod J Rohrich
Division of Plastic and Reconstructive Surgery, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard E7 212, Dallas, TX 75390 9132, USA
Plast Reconstr Surg 110:860-69; quiz 870. 2002..2. The etiology and epidemiology of rhinophyma. 3. Associated diagnosis that can complicate rhinophyma. 4. Common nonsurgical and surgical therapies for rhinophyma. 5. A safe and integrated treatment plan for the patient with rhinophyma...
- Prevalence of rosacea in an Estonian working population using a standard classificationKristi Abram
Clinic of Dermatology, University of Tartu, EE 50417 Tartu, Estonia
Acta Derm Venereol 90:269-73. 2010Data about the prevalence of rosacea are scarce. The aim of this study was to evaluate the prevalence rate of rosacea according to the American National Rosacea Society Expert Committee (NRSEC) classification...
- Glycomics analyses of tear fluid for the diagnostic detection of ocular rosaceaHyun Joo An
Department of Chemistry, University of California, Davis, California 95616, USA
J Proteome Res 4:1981-7. 2005A Glycomics approach to detect disease is illustrated in the analyses of human tear fluid for rosacea. The diagnosis of ocular rosacea is particularly challenging in a subgroup of patients that do not present with typical facial skin ..
- Beneficial use of Cetaphil moisturizing cream as part of a daily skin care regimen for individuals with rosaceaSabine Laquieze
PERITESCO, Paris, France
J Dermatolog Treat 18:158-62. 2007b>Rosacea is a common and chronic disorder characterized by flushing, erythema, papules, pustules, and telangiectasia on the central part of the face...
- Poikiloderma of civatte and rosacea: variants in the same nosological spectrum?Alexander C Katoulis
Dermatology 211:386-7. 2005
- Effective treatment of rosacea using intense pulsed light systemsCareen A Schroeter
Department of Lasertherapy, Medical Centre Maastricht, Becanusstraat 17 A05, 6216 BX Maastricht, The Netherlands
Dermatol Surg 31:1285-9. 2005To date, a variety of lasers have been used for treating vascular skin lesions. Intense pulsed light (IPL) is a proven technology for vascular lesion management, such as rosacea.
- Efficacy of topical cyclosporine for the treatment of ocular rosaceaBarry A Schechter
Florida Eye Microsurgical Institute, 1717 W Woolbright Road, Boynton Beach, Florida, FL 33426, USA
Adv Ther 26:651-9. 2009This study was designed to compare the efficacy of cyclosporine ophthalmic emulsion 0.05% with an artificial tear solution for the treatment of rosacea-associated eyelid and corneal pathology.
- [Epidemiology of rosacea: updated data]O Chosidow
Service de Dermatologie, Hopital Henri Mondor, 51, Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
Ann Dermatol Venereol 138:S124-8. 2011The epidemiological data on rosacea remain fragmentary and the methodological quality debatable. Rosacea affects mainly adults around the age of 30 years and classically predominates in females...
- Retrospective analysis of the association between Demodex infestation and rosaceaYa E Zhao
Department of Immunology and Pathogen Biology, Medical School of Xi an Jiaotong University, No 76 Yanta W Road, Xi an, China
Arch Dermatol 146:896-902. 2010To explore the association between Demodex infestation and rosacea and the pathogenesis of demodicosis rosacea by means of a meta-analysis.
- Rosacea and atopic dermatitis. Two common oculocutaneous disordersBenjamin Barankin
University of Alberta, Edmonton
Can Fam Physician 48:721-4. 2002..To increase awareness of the oculocutaneous manifestations of two common skin diseases...
- Oral azithromycin for treatment of intractable rosaceaJae Hong Kim
Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea
J Korean Med Sci 26:694-6. 2011b>Rosacea is a common chronic cutaneous disorder that primarily occurs on the convex surfaces of the central face and is often characterized by exacerbations and remissions...
- Pimecrolimus 1% cream for the treatment of rosaceaMoon Bum Kim
Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea
J Dermatol 38:1135-9. 2011b>Rosacea is a common inflammatory skin disorder; the pathogenesis is unclear. Various treatment options for rosacea are available, but most have limited effectiveness...
- Gnatophyma: a rare rosacea phyma variantErum N Ilyas
J Am Acad Dermatol 55:165-6. 2006
- Pulsed dye laser treatment of rosacea improves erythema, symptomatology, and quality of lifeStephen R Tan
Division of Dermatologic Surgery, Indiana University School of Medicine, University of Minnesota, USA
J Am Acad Dermatol 51:592-9. 2004Persistent erythema and dysesthetic symptoms are typical manifestations of rosacea.
- Cutaneous Rosai-Dorfman disease presenting as a granulomatous rosacea-like rashsXiu yan Shi
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China
Chin Med J (Engl) 124:793-4. 2011A case of cutaneous Rosai-Dorfman disease (CRDD) presenting as a granulomatous rosacea-like rashs was reported. A 45-year-old Chinese woman presented with a 1-month history of a widespread nonpruiginous papulonodular eruption...
- Rosacea - global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert GroupB E Elewski
Department of Dermatology, University of Alabama, Birmingham, AL, USA
J Eur Acad Dermatol Venereol 25:188-200. 2011..of specific histological or serological markers, the gaps in understanding the aetiology and pathophysiology of rosacea, and the broad diversity in its clinical manifestations has made it difficult to reach international consensus on ..
- Combined effects of silymarin and methylsulfonylmethane in the management of rosacea: clinical and instrumental evaluationEnzo Berardesca
San Gallicano Dermatological Institute, Rome, Italy
J Cosmet Dermatol 7:8-14. 2008This study aims to evaluate a topical treatment based on silymarin/methylsulfonilmethane (S-MSM) to improve erythematous-telangiectactic rosacea.
- Association of rosacea with demodicosisHamideh Moravvej
Skin Research Center, Department of Dermatology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
Arch Iran Med 10:199-203. 2007There are controversial reports about the role of Demodex mites in pathogenesis of acne rosacea. The aim of this study was to examine the relationship between the presence and number of Demodex mites and the pathogenesis of rosacea.
- Rosacea: a common, yet commonly overlooked, conditionB Wayne Blount
Department of Family Medicine, University of Tennessee Health Science Center, Memphis 38104, USA
Am Fam Physician 66:435-40. 2002b>Rosacea is a common, but often overlooked, skin condition of uncertain etiology that can lead to significant facial disfigurement, ocular complications, and severe emotional distress...
- Distribution and expression of non-neuronal transient receptor potential (TRPV) ion channels in rosaceaMathias Sulk
Department of Dermatology, University Hospital Munster, Munster, Germany
J Invest Dermatol 132:1253-62. 2012b>Rosacea is a frequent chronic inflammatory skin disease of unknown etiology. Because early rosacea reveals all characteristics of neurogenic inflammation, a central role of sensory nerves in its pathophysiology has been discussed...
- Expression of vascular endothelial growth factor and its receptors in rosaceaJustine R Smith
Casey Eye Institute, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Biomedical Research Building, Mail Code L467AD, Portland, OR 97239, USA
Br J Ophthalmol 91:226-9. 2007b>Rosacea is a common chronic disease of unclear pathogenesis, characterised by inflammation and vascular abnormalities of the facial skin and ocular surface...
- Rosacea treatment using the new-generation, high-energy, 595 nm, long pulse-duration pulsed-dye laserEric F Bernstein
Laser Surgery and Cosmetic Dermatology Centers, Bryn Mawr, Pennsylvania, USA
Lasers Surg Med 40:233-9. 2008b>Rosacea results from sun-induced hyper-vascularity of exposed facial skin, often accompanied by acneiform papules and pustules...
- Enhanced skin blood flow and sensitivity to noxious heat stimuli in papulopustular rosaceaDaniela A Guzman-Sanchez
Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
J Am Acad Dermatol 57:800-5. 2007Although patients with rosacea often complain of increased skin sensitivity, there has been no quantitative sensory testing of this phenomenon...
- Cutaneous and ocular signs of childhood rosaceaMelanie Chamaillard
Unité de dermatologie pédiatrique, Place Amelie Raba Leon, 33 076 Bordeaux Cedex, France
Arch Dermatol 144:167-71. 2008Objectives To describe the clinical features of cutaneous and ocular manifestations of childhood rosacea, to propose diagnostic criteria, and to emphasize the possible severity of ocular complications in this age group.
- Granulomatous rosacea-like demodicidosisJulia Yu Yun Lee
Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Dermatol Online J 13:9. 2007Demodicidosis may present as pityriasis folliculitis, papulopustular lesions, rosacea-like eruptions, and granulomatous rosacea-like eruptions...
- Gnatophyma and otophymaNavid Ezra
Division of Dermatology, Department of Medicine, David Geffen Schoool of Medicine at UCLA, Los Angeles, CA, USA
J Cutan Med Surg 13:266-72. 2009Phymas are slowly progressive, disfiguring disorders of the face and ears that represent the end stage of rosacea. The most common phyma is rhinophyma, yet similar swellings may occur on the chin (gnatophyma), forehead (metophyma), one ..
- Correlation between ocular Demodex infestation and serum immunoreactivity to Bacillus proteins in patients with Facial rosaceaJianjing Li
Ocular Surface Center, Miami, Florida 33173, USA
Ophthalmology 117:870-877.e1. 2010..To investigate correlation between ocular Demodex infestation and serum...
- Rosacea: 244 Tunisian casesAida Khaled
Department of Dermatology, Charles Nicolle Hospital, Tunis, Tunisia
Tunis Med 88:597-601. 2010b>Rosacea is a common, chronic facial dermatosis of uncertain etiology, several well-defined types and variable progression. There is a paucity of epidemiologic studies from North African countries especially in Tunisia.
- Demodex folliculorum in development of dermatitis rosaceiformis steroidica and rosacea-related diseasesAleksandra Basta-Juzbasic
Department of Dermatology and Venerology, Zagreb University Hospital Center, Zagreb, Croatia
Clin Dermatol 20:135-40. 2002
- Topical corticosteroid-induced rosacea-like dermatitis: a clinical study of 110 casesSanjay K Rathi
Dermatologist, Siliguri, West Bengal, India
Indian J Dermatol Venereol Leprol 77:42-6. 2011Prolonged and continuous use of topical steroids leads to rosacea-like dermatitis with variable clinical presentations.
- Demodicosis and rosacea: epidemiology and significance in daily dermatologic practiceFabienne Forton
J Am Acad Dermatol 52:74-87. 2005..Demodicoses are thought to be rare, occurring mainly for patients with immunosuppression...
- Incidental control of rosacea by somatostatinClaudine Pierard-Franchimont
Department of Dermatopathology, University Medical Center of Liege, Belgium
Dermatology 206:249-51. 2003The precise pathomechanism of rosacea remains elusive. The disease commonly requires long-term treatments using topical or oral therapies.
- Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosaceaJianxing Zhang
Center for Therapeutic Biomaterials, University of Utah, Salt Lake City, Utah, United States of America
PLoS ONE 6:e16658. 2011b>Rosacea is a common disfiguring skin disease of primarily Caucasians characterized by central erythema of the face, with telangiectatic blood vessels, papules and pustules, and can produce skin thickening, especially on the nose of men, ..
- Anti-inflammatory dose doxycycline (40 mg controlled-release) confers maximum anti-inflammatory efficacy in rosaceaKlaus Theobald
CollaGenex Pharmaceuticals Inc, 41 University Drive, Newtown, PA 18940, USA
Skinmed 6:221-6. 2007..recently demonstrated the efficacy of a 40-mg controlled-release formulation of doxycycline in the treatment of rosacea, a dose well below the conventional level of 100 to 200 mg/d...
- A pilot quality-of-life instrument for acne rosaceaKimberly Nicholson
Department of Dermatology, Emory University School of Medicine, Atlanta, GA 30322, USA
J Am Acad Dermatol 57:213-21. 2007No rosacea-specific quality-of-life (QOL) instrument exists.
- Gnatophyma: a rare variant of phymaM R Vidigal
Dermatology Service, Hospital Complex Padre Bento de Guarulhos, Sao Paulo, Brazil
Clin Exp Dermatol 33:743-4. 2008We report a case of a 44-year-old woman with an 8-year history of gnatophyma. Rosacea is a facial dermatosis that may present as flushing, erythema, telangiectases, papules, pustules and phyma...
- Antibiotic use in acne vulgaris and rosacea: clinical considerations and resistance issues of significance to dermatologistsJames Q Del Rosso
Department of Dermatology, University of Nevada School of Medicine, Las Vegas, USA
Cutis 82:5-12. 2008..Antibiotics are commonly prescribed in dermatology practice for a variety of disorders, including acne vulgaris and rosacea. Importantly, they often are used long-term for these inflammatory dermatoses...
- Otophyma: a case report and review of the literature of lymphedema (elephantiasis) of the earJ Andrew Carlson
Division of Dermatology, Albany Medical College, 47 New Scotland Ave, Albany, NY 12208, USA
Am J Dermatopathol 30:67-72. 2008Phymas (swellings, masses, or bulbs) are considered the end-stage of rosacea and mostly affect the nose (rhinophyma), and rarely involve the chin (gnatophyma), the cheek (metophyma), eyelids (blepharophyma), or ears (otophyma)...
- BsmI polymorphism of the vitamin D receptor gene in patients with the fulminant course of rosacea conglobata (rosacea fulminans)Thomas Jansen
J Dermatol 31:244-6. 2004
- A study of the pathogenesis of rosacea: how angiogenesis and mast cells may participate in a complex multifactorial processKyriaki Aroni
Department of Dermatopathology, Medical School, University of Athens, Athens, Greece
Arch Dermatol Res 300:125-31. 2008In the present study we evaluated, in involved and clinically uninvolved skin of Rosacea, microvessels density (MVD) and total vascular area (TVA) in addition to multiple morphologic characteristics of microvessels and also mast cells (..
- Intestinal alkaline phosphatase: the molecular link between rosacea and gastrointestinal disease?Joanne Whitehead
UMR 168 CNRS Institut Curie, 11 rue Pierre et Marie Curie, 75005 Paris, France
Med Hypotheses 73:1019-22. 2009b>Rosacea is a common inflammatory condition of the facial skin of unknown etiology, which frequently occurs in combination with gastrointestinal disorders...
- Laser treatment of erythema and telangiectasia associated with rosaceaS M Clark
Department of Dermatology, The University Hospital of Wales, Heath Park, Cardiff, UK
Lasers Med Sci 17:26-33. 2002The response of rosacea-associated erythema and telangiectasia to treatment with the pulsed tunable dye laser (PDL) was evaluated in 12 patients...
- Systemic therapy for rosaceaH E Baldwin
Department of Dermatology, State University of New York, Brooklyn, NY, USA
Skin Therapy Lett 12:1-5, 9. 2007b>Rosacea is a common condition that affects people of all races. In addition to the visible aspects of this disease, it can have a psychosocial impact that must be evaluated when considering the treatment options...
- Pimecrolimus 1% cream for the treatment of steroid-induced rosacea: an 8-week split-face clinical trialD H Lee
Department of Dermatology, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Korea
Br J Dermatol 158:1069-76. 2008Steroid-induced rosacea is a relatively common dermatosis that is caused by the prolonged application of topical steroid to the face.
- The potential role of microorganisms in the development of rosaceaElizabeth Lazaridou
First Department of Dermatology Venereology, Aristotle University Medical School, Thessaloniki, Greece
J Dtsch Dermatol Ges 9:21-5. 2011b>Rosacea is a chronic cutaneous disorder characterized by centrofacial persisting erythema, telangiectases, papules, pustules, edema, phymas and ocular involvement...
- The prevalence of ocular signs in acne rosacea: comparing patients from ophthalmology and dermatology clinicsVinicius Coral Ghanem
Department of Ophthalmology, University of California, Davis, Sacramento 95817, USA
Cornea 22:230-3. 2003To describe and compare the ocular signs in patients diagnosed with acne rosacea by the ophthalmologist with the ocular signs in the patients diagnosed with rosacea by the dermatologist.
- Density of Demodex folliculorum in rosacea: a case-control study using standardized skin-surface biopsyF Forton
Clinic of Dermatology, Saint Pierre University Hospital, Universite Libre de Bruxelles, Belgium
Br J Dermatol 128:650-9. 1993A standardized skin-surface biopsy (1 cm2) of the check was performed in 49 patients with rosacea [13 with erythemato-telangiectatic rosacea (ETR), three with squamous rosacea (SR), 33 with papulopustular rosacea (PPR)], and 45 controls...
- Ocular signs, symptoms and tear function tests of papulopustular rosacea patients receiving azithromycinO Bakar
Department of Dermatology, Acibadem Kozyatagi Hospital, Istanbul, Turkey
J Eur Acad Dermatol Venereol 23:544-9. 2009Tetracycline derivatives provide moderate benefit in the treatment of ocular rosacea. Recently, azithromycin has been found to be an effective alternative in the treatment of cutaneous papulopustular rosacea.
- Childhood rosaceaB Drolet
Department of Pediatrics and Dermatology, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois
Pediatr Dermatol 9:22-6. 1992b>Rosacea usually occurs in adults and rarely has been noted in children. We recently observed three children with rosacea, all of whom responded dramatically to systemic and topical antibiotics...
- A comparison of 15% azelaic acid gel and 0.75% metronidazole gel in the topical treatment of papulopustular rosacea: results of a randomized trialBoni E Elewski
Department of Dermatology, University of Alabama at Birmingham, 35233, USA
Arch Dermatol 139:1444-50. 2003..75% metronidazole gel (MetroGel; Galderma Laboratories LP, Fort Worth, Tex) as topical therapy for moderate, papulopustular facial rosacea.
- Doxycycline 40 mg capsules (30 mg immediate-release/10 mg delayed-release beads): anti-inflammatory dose in rosaceaKate McKeage
Adis, a Wolters Kluwer Business, Auckland, New Zealand
Am J Clin Dermatol 11:217-22. 2010..delayed-release beads) provide a sub-antimicrobial dose that reduces the inflammatory response in patients with rosacea without producing drug concentrations required to treat bacterial diseases...
- Kaposi's varicelliform eruption in association with rosaceaIsil Kucukyilmaz
Department of Dermatology, Akdeniz University School of Medicine, Antalya, Turkey
J Am Acad Dermatol 51:S169-72. 2004..We report here a new case of Kaposi's varicelliform eruption in a 38-year-old woman with rosacea. To our knowledge, this is the first case of Kaposi's varicelliform eruption associated with rosacea to be ..
- Antimicrobials in the treatment of acne and rosaceaJoseph A Witkowski
Skinmed 2:202. 2003
- Rosacea: skin innate immunity gone awry?Charles L Bevins
Nat Med 13:904-6. 2007
- Azithromycin in the treatment of papulopustular rosaceaTugrul Dereli
Department of Dermatology, Medical Faculty of Ege University, Izmir, Turkey
J Dermatol 32:926-8. 2005
- TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytesKenshi Yamasaki
Division of Dermatology, Department of Medicine, University of California, San Diego, VA San Diego Health Care System, San Diego, California, USA
J Invest Dermatol 131:688-97. 2011..b>Rosacea is a common skin disease that manifests unique inflammatory responses to normal environmental stimuli...
- Objective and quantitative improvement of rosacea-associated erythema after intense pulsed light treatmentKenneth A Mark
Department of Dermatology, New York University School of Medicine, New York, USA
Dermatol Surg 29:600-4. 2003..In addition, very few studies specifically address rosacea-associated erythema.
- Oral tetracyclines for ocular rosacea: an evidence-based review of the literatureDonald U Stone
Molecular Pathogenesis of Eyer Infection Research Center, Dean A McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center, 608 Stanton I Young Boulevard, Oklahoma City, OK 73104, USA
Cornea 23:106-9. 2004To review the basis for the use of oral tetracyclines in ocular rosacea.
- Therapeutic potential of azithromycin in rosaceaOzgür Bakar
Department of Dermatology, Marmara University School of Medicine, Istanbul, Turkey
Int J Dermatol 43:151-4. 2004Systemic antibiotics currently used in the treatment of rosacea are sometimes associated with uncomfortable side-effects. Therefore, a need for an effective agent with few side-effects and good patient compliance exists...
- Systematic review of rosacea treatmentsEsther J Van Zuuren
Department of Dermatology B1 Q, Leiden University Medical Center, The Netherlands
J Am Acad Dermatol 56:107-15. 2007b>Rosacea is a common chronic skin and ocular condition. It is unclear which treatments are most effective. We have conducted a Cochrane review of rosacea therapies. This article is a distillation of that work.
- Reactive oxygen species and rosaceaDavid Jones
Department of Dermatology, Harvard Medical School, Cambridge, Massachusetts, USA
Cutis 74:17-20, 32-4. 2004Although the fundamental pathogenesis of rosacea remains unknown, inflammation is a central process in this disorder...
- Standard classification of rosacea: Report of the National Rosacea Society Expert Committee on the Classification and Staging of RosaceaJonathan Wilkin
Division of Dermatologic and Dental Drug Products, Food and Drug Administration, Rockville, MD, USA
J Am Acad Dermatol 46:584-7. 2002
- Staphylococcus epidermidis: a possible role in the pustules of rosaceaMargot Whitfeld
Department of Dermatology, St Vincent s Hospital, Sydney, Australia
J Am Acad Dermatol 64:49-52. 2011b>Rosacea is a common skin and ocular disease. Cutaneous rosacea is characterized by facial flushing, telangiectasia, papules, and pustules. It is generally regarded as inflammatory in nature...
- Lymphangiogenesis and angiogenesis in non-phymatous rosaceaAmal H A Gomaa
Dermatopathology Section, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118, USA
J Cutan Pathol 34:748-53. 2007Our study evaluated the expression of vascular endothelial growth factor (VEGF), CD31 and D2-40 in involved and uninvolved skin of 18 patients with rosacea.
- Tacrolimus ointment for the treatment of steroid-induced rosacea: a preliminary reportD Goldman
Department of Dermatology, NorthBay Healthcare Medical Group, Fairfield, CA 94533, USA
J Am Acad Dermatol 44:995-8. 2001Excessive topical corticosteroid application to facial areas commonly leads to steroid-induced rosacea. This may be a recalcitrant problem that requires months of antibiotic and anti-inflammatory therapy before it resolves.
- The impact of rosacea on quality of life: effects of demographic and clinical characteristics and various treatment modalitiesB Aksoy
Dermatology Clinic, TDV 29 Mayis Private Ankara Hospital, Ankara, Turkey
Br J Dermatol 163:719-25. 2010b>Rosacea has a major psychosocial impact on a patient's life.
- Oral use of azithromycin for the treatment of acne rosaceaAdolfo Fernandez-Obregon
Arch Dermatol 140:489-90. 2004
- The effect of azithromycin on reactive oxygen species in rosaceaO Bakar
Department of Dermatology, Acibadem Kozyatagi Hospital, Istanbul, Turkey
Clin Exp Dermatol 32:197-200. 2007Recent evidence suggests that inflammation in rosacea is associated with generation of reactive oxygen species (ROS) that are released by inflammatory cells...
- Small intestinal bacterial overgrowth in rosacea: clinical effectiveness of its eradicationAndrea Parodi
Department of Internal Medicine, Gastroenterology Unit, University of Genoa, Genoa, Italy
Clin Gastroenterol Hepatol 6:759-64. 2008To better understand the role of small intestinal bacterial overgrowth (SIBO) in rosacea, we aimed to assess the presence of SIBO in patients with rosacea and the clinical effectiveness of its eradication.
- Pediatric ocular acne rosacea: long-term treatment with systemic antibioticsAltug Cetinkaya
Baskent University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey
Am J Ophthalmol 142:816-21. 2006To report our experience with four cases of pediatric ocular acne rosacea, including responses to long-term systemic treatment.
- Steroid-induced rosaceaJ Z Litt
Case Western Reserve University School of Medicine, Cleveland, Ohio
Am Fam Physician 48:67-71. 1993..the face often produces an array of skin complications, including an eruption clinically indistinguishable from rosacea ("iatrosacea")...
- Use of the KTP laser in the treatment of rosacea and solar lentiginesBenjamin A Bassichis
University of Texas Southwestern Medical Center Division of Facial Plastic and Reconstructive Surgery, Veterans Administration Hospital, Dallas, TX, USA
Facial Plast Surg 20:77-83. 2004Numerous techniques have evolved in facial plastic surgery to treat rosacea and solar lentigines...
- Update on rosacea pathogenesis and correlation with medical therapeutic agentsJames Q Del Rosso
Department of Dermatology, University of Nevada School of Medicine, Las Vegas, USA
Cutis 78:97-100. 2006The pathogenesis of rosacea is poorly understood, though clinical features of the disease are well-recognized. This article updates current views on mechanisms potentially associated with rosacea...
- Comparative study of some treatment modalities of rosaceaF F Mostafa
Department of Dermatology and Venereology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
J Eur Acad Dermatol Venereol 23:22-8. 2009b>Rosacea is a disease of complex pathogenesis and variable response to various therapeutic methods. Aim of the work To evaluate and compare the efficacy, safety and side effects of some topical lines of treatment of rosacea.
- Effect of Helicobacter pylori eradication therapy in rosacea patientsD Boixeda de Miquel
Department of Gastroenterology, Hospital Ramon y Cajal, Madrid, Spain
Rev Esp Enferm Dig 98:501-9. 2006The causal relation between rosacea and Helicobacter pylori infection is discussed. We evaluated the clinical evolution of rosacea after infection eradication.
- Comparison of anti-inflammatory dose doxycycline versus doxycycline 100 mg in the treatment of rosaceaJames Q Del Rosso
Valley Hospital Medical Center, Las Vegas, NV 89121, USA
J Drugs Dermatol 7:573-6. 2008
- The ocular manifestations of atopic dermatitis and rosaceaAndrew S Eiseman
Eye Clinic, Walter Reed Army Medical Center, Washington, DC 20307, USA
Curr Allergy Asthma Rep 6:292-8. 2006Atopic dermatitis and rosacea are chronic diseases that have both dermatologic and ocular manifestations. The occurrence of ocular disease is often proportionately higher than that of dermatologic disease...
- [Repair of an extensive corneoscleral perforation in a case of ocular rosacea with a keratoplasty]B Gracner
Lehrkrankenhaus Maribor, Augenabteilung, Maribor, Slowenien
Klin Monbl Augenheilkd 223:841-3. 2006A 58-year-old female patient with rosacea and a 7year history of eye trouble presented with a spontaneous corneoscleral perforation of the left eye.
- Comparative efficacy of nonpurpuragenic pulsed dye laser and intense pulsed light for erythematotelangiectatic rosaceaIsaac M Neuhaus
Dermatologic Surgery and Laser Center, Department of Dermatology, University of California, San Francisco, 1701 Divisadero Street, 3rd Floor, San Francisco, CA 94115, USA
Dermatol Surg 35:920-8. 2009Erythematotelangiectatic (ET) rosacea is commonly treated with a variety of laser and light-based systems. Although many have been used successfully, there are a limited number of comparative efficacy studies.
- Facial Sweet's syndrome mimicking rosacea fulminansNamrata S Anavekar
Department of Dermatology, St Vincent s Hospital, Melbourne, Victoria, Australia
Australas J Dermatol 48:50-3. 2007..The initial clinicopathological diagnosis was rosacea fulminans, which was treated with 25 mg oral prednisolone and cephalexin...
- Oxidative stress and ferritin expression in the skin of patients with rosaceaVesna Sredoja Tisma
Polyclinic Department of Dermatology and Venereology, Dubrava University Hospital, Zagreb, Croatia
J Am Acad Dermatol 60:270-6. 2009b>Rosacea is a common chronic light-sensitive inflammatory skin disease of unknown origin...
- Amniotic membrane transplantation in ocular rosaceaArun K Jain
Cornea and External Diseases Section, Department of Ophthalmology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India
Ann Ophthalmol (Skokie) 39:71-3. 2007A 40-year-old patient with the diagnosis of acne rosacea presented with perforated peripheral corneal ulcer. Three applications of cyanoacrylate glue along with bandage contact lens failed to seal the perforation...
- Updates on the pathophysiology and management of acne rosaceaMohamed L Elsaie
Department of Dermatology and Cutaneous Surgery, University of Miami, Miami, FL 33136, USA
Postgrad Med 121:178-86. 2009There are many options for the treatment of acne rosacea, including topical and systemic therapies, laser and light-based therapies, and surgical procedures...
- Successful treatment of the erythema and flushing of rosacea using a topically applied selective alpha1-adrenergic receptor agonist, oxymetazolineStuart D Shanler
School of Medicine, University of New Mexico, Albuquerque, USA
Arch Dermatol 143:1369-71. 2007
- Increased serine protease activity and cathelicidin promotes skin inflammation in rosaceaKenshi Yamasaki
Division of Dermatology, University of California, San Diego, and VA San Diego Health Care System, 3350 La Jolla Village Drive, San Diego, California 92161, USA
Nat Med 13:975-80. 2007Acne rosacea is an inflammatory skin disease that affects 3% of the US population over 30 years of age and is characterized by erythema, papulopustules and telangiectasia...
- Combined effect of anti-inflammatory dose doxycycline (40-mg doxycycline, usp monohydrate controlled-release capsules) and metronidazole topical gel 1% in the treatment of rosaceaJoseph F Fowler
Department of Medicine, Division of Dermatology, University of Louisville, Louisville, KY, USA
J Drugs Dermatol 6:641-5. 2007Research into the pathophysiology of rosacea suggests a central role for inflammatory mediators such as nitric oxide (NO), reactive oxygen species (ROS), and matrix metalloproteinases (MMPs)...
- Cytokine Signaling in Neurons: Inflammation, Pain and PruritisMartin Steinhoff; Fiscal Year: 2013..novel therapeutic strategies to combat skin diseases that have a neuronal component, like atopic dermatitis and other eczemas, or rosacea, and to reduce the adverse symptoms associated with these conditions, including pruritus and pain.
- Novel Glycosaminoglycan Derivatives for Treatment of Bladder InflammationJUSTIN RODNEY SAVAGE; Fiscal Year: 2011..We have developed a murine model of bladder inflammation extrapolated from the pathophysiology of skin lesions in rosacea, which express high levels of the antimicrobial cathelicidin peptide LL-37...
- Skin Defense by Antimicrobial Peptides Richard L Gallo; Fiscal Year: 2012..We have discovered much about the etiology of rosacea and why patients with atopic dermatitis are susceptible to infection...
- Proteolysis and Skin AntimicrobialsRichard L Gallo; Fiscal Year: 2013..Control of this processing is relevant to skin diseases ie. rosacea and psoriasis...
- A Novel Class of Therapeutic Agents for the Treatment of Skin Diseases AssociatedJoel S Gordon; Fiscal Year: 2010..g. atopic dermatitis, seborrheic dermatitis) and rosacea. PUBLIC HEALTH RELEVANCE: Treatment for chronic inflammatory skin diseases characterized by a prominent degree of ..
- Safety and Efficacy of Single-use Cliradex Pads for Ocular MitesScheffer C G Tseng; Fiscal Year: 2012..Uncontrolled overgrowth of mites has been implicated in causing papulopustular lesions in the skin, rosacea in the face, and blepharitis in the eye...
- Sulfated Polysaccharide Derivatives for the Treatment of RosaceaNARAYANAM RAO; Fiscal Year: 2009b>Rosacea is a common disfiguring skin disease affecting 3% of the population over 30 years of age, or 14 million Americans...
- Cathelicidin in Skin ImmunityVictor Nizet; Fiscal Year: 2013..showing abnormal production contributes to the pathophysiology of skin diseases such as atopic dermatitis, rosacea and psoriasis...
- A Topical Non Steroidal Anti-inflammatory for RosaceaEduardo Perez; Fiscal Year: 2013DESCRIPTION (provided by applicant): Rosacea is a chronic dermatological condition characterized by flushing, erythema, papules, pustules, inflammatory nodules and telangiectasia...
- Tea Tree Oil for Treating Ocular Demodex InfestationScheffer Tseng; Fiscal Year: 2009..Uncontrolled overgrowth of these mites has been implicated in causing rosacea in the face, blepharitis in the eyelid, and other inflammation-associated conjunctival and corneal abnormalities...
- TEAR FUNCTION IN BLEPHARITIS AND DRY EYEWilliam Mathers; Fiscal Year: 2000..2d) Evaluate patients with Rosacea and seborrheic dermatitis to determine the effects of these dermatologic diseases on the tear film...
- Goblet Cell Stimulation Via Electric Charge Flux & FieldBRADLEY VEATCH; Fiscal Year: 2005..patients at increased risk for the disease, including diabetes, lupus, arthritis, leukemia, fibromyalgia, acne rosacea, and Sjogren's syndrome...
- 2007 Antimicrobial Peptides Gordon ConferenceRichard Gallo; Fiscal Year: 2007..The organizational philosophy is to encourage diverse[unreadable] participation, and maintain an eye towards gender issues, junior scientists, minorities, and individuals with[unreadable] physical limitations. ..
- PROTEOGLYCANS WOUND REPAIR AND INFLAMMATIONRichard Gallo; Fiscal Year: 2005..The GAG ligand(s) responsible for activation will be sought and gene expression profiles investigated. Successful completion of these aims will reveal fundamental events in wound repair and may suggest new approaches to wound therapy. ..
- Mechanisms of Tumor Promotion Effects of B[a]PDEChuanshu Huang; Fiscal Year: 2008..Such agents could interfere with the signaling pathways leading to AP-1 activation. ..
- Values of Families in Guiding End-of-Life CareCharles Gessert; Fiscal Year: 2002..This research will lay the groundwork for two future studies: a survey of values in end-of-life decision-making, and an in depth examination of the role of selected values in decision-making. ..
- Chemoprevention of Esophageal Squamous Cell CarcinomaGary Stoner; Fiscal Year: 2004..abstract_text> ..
- Role of Retinal Microvasculature in Posterior UveitisJustine Smith; Fiscal Year: 2006..The studies should also have implications for unrelated diseases affecting the retinal circulation, as well as tissue-specific inflammations and infections at other body sites. [unreadable] [unreadable]..
- Effects of Arsenic on PI-3K Signaling PathwayChuanshu Huang; Fiscal Year: 2007..Such agents could interfere with signaling pathways leading to cyclin D1 induction, cell proliferation and cell transformation. ..
- Nitric Oxide Synthase Polymorphisms and Risk for Skin CancerAbrar Qureshi; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..