pityriasis rubra pilaris

Summary

Summary: A chronic skin disease characterized by small follicular papules, disseminated reddish-brown scaly patches, and often, palmoplantar hyperkeratosis. The papules are about the size of a pin and topped by a horny plug.

Top Publications

  1. ncbi Pityriasis rubra pilaris: a clinical review
    David Jerard Pincus
    Jackson Memorial Hospital, Miami, FL, USA
    Dermatol Nurs 17:448-51. 2005
  2. ncbi [How I treat...pityriasis rubra pilaris]
    A L Fraiture
    Service de Dermatopathologie, Universite de Liege
    Rev Med Liege 57:363-5. 2002
  3. ncbi Living with pityriasis rubra pilaris
    Ralph E Gilmore
    American Airlines, Arlington, TX, USA
    Dermatol Nurs 17:378-80. 2005
  4. ncbi [Pityriasis rubra pilaris]
    S Artik
    Hautklinik der Heinrich Heine Universität, Dusseldorf
    Hautarzt 55:980-3. 2004
  5. ncbi [A case of pityriasis rubra pilaris associated with rapidly progressive finger joint destruction]
    Hirokazu Ohashi
    First Department of Internal Medicine, School of Medicine, Sapporo Medical University
    Nihon Rinsho Meneki Gakkai Kaishi 27:407-13. 2004
  6. pmc Familial pityriasis rubra pilaris is caused by mutations in CARD14
    Dana Fuchs-Telem
    Department of Dermatology, Tel Aviv Sourasky Medical Center, Israel
    Am J Hum Genet 91:163-70. 2012
  7. ncbi Pityriasis rubra pilaris: a review of diagnosis and treatment
    Annette Klein
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Am J Clin Dermatol 11:157-70. 2010
  8. doi Pityriasis rubra pilaris exacerbation with topical use of imiquimod
    F Clarissa Yang
    Department of Dermatology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Int J Dermatol 47:1076-8. 2008
  9. ncbi Dermatomyositis with a pityriasis rubra pilaris-like eruption: an uncommon cutaneous manifestation in dermatomyositis
    Muhterem Polat
    1st Dermatology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey
    Pediatr Dermatol 24:151-4. 2007
  10. ncbi Pityriasis rubra pilaris: an unusual cutaneous complication of AIDS
    R A Bonomo
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Med Sci 314:118-21. 1997

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Scientific Experts

Detail Information

Publications119 found, 100 shown here

  1. ncbi Pityriasis rubra pilaris: a clinical review
    David Jerard Pincus
    Jackson Memorial Hospital, Miami, FL, USA
    Dermatol Nurs 17:448-51. 2005
    b>Pityriasis rubra pilaris is a skin condition with many different clinical presentations. History, histology, clinical presentation, its different classified forms, treatments, and differential diagnoses are reviewed.
  2. ncbi [How I treat...pityriasis rubra pilaris]
    A L Fraiture
    Service de Dermatopathologie, Universite de Liege
    Rev Med Liege 57:363-5. 2002
    b>Pityriasis rubra pilaris is a syndrome of unknown etiology. Six distinct clinical types have been described in infancy and adulthood. Oral retinoids have proven their efficacy...
  3. ncbi Living with pityriasis rubra pilaris
    Ralph E Gilmore
    American Airlines, Arlington, TX, USA
    Dermatol Nurs 17:378-80. 2005
  4. ncbi [Pityriasis rubra pilaris]
    S Artik
    Hautklinik der Heinrich Heine Universität, Dusseldorf
    Hautarzt 55:980-3. 2004
    b>Pityriasis rubra pilaris (PRP) is a rare papulosquamous disease with typical onset during the first and fifth decades. The skin disorder normally starts on the scalp and spreads caudally within a few weeks...
  5. ncbi [A case of pityriasis rubra pilaris associated with rapidly progressive finger joint destruction]
    Hirokazu Ohashi
    First Department of Internal Medicine, School of Medicine, Sapporo Medical University
    Nihon Rinsho Meneki Gakkai Kaishi 27:407-13. 2004
    ..b>Pityriasis rubra pilaris (PRP) was diagnosed in 1996 in the Department of Dermatology at Sapporo Medical University hospital...
  6. pmc Familial pityriasis rubra pilaris is caused by mutations in CARD14
    Dana Fuchs-Telem
    Department of Dermatology, Tel Aviv Sourasky Medical Center, Israel
    Am J Hum Genet 91:163-70. 2012
    b>Pityriasis rubra pilaris (PRP) is a papulosquamous disorder phenotypically related to psoriasis. The disease has been occasionally shown to be inherited in an autosomal-dominant fashion...
  7. ncbi Pityriasis rubra pilaris: a review of diagnosis and treatment
    Annette Klein
    Department of Dermatology, University of Regensburg, Regensburg, Germany
    Am J Clin Dermatol 11:157-70. 2010
    b>Pityriasis rubra pilaris (PRP) is a rare inflammatory dermatosis of unknown etiology, and finding a successful therapy can be challenging. PRP occurs equally in men and women...
  8. doi Pityriasis rubra pilaris exacerbation with topical use of imiquimod
    F Clarissa Yang
    Department of Dermatology, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Int J Dermatol 47:1076-8. 2008
    ..We report the case of a 67-year-old man who was treated with imiquimod for actinic keratosis and developed fever and a progressive erythematous papulosquamous eruption that was histologically consistent with pityriasis rubra pilaris.
  9. ncbi Dermatomyositis with a pityriasis rubra pilaris-like eruption: an uncommon cutaneous manifestation in dermatomyositis
    Muhterem Polat
    1st Dermatology Department, Ankara Numune Education and Research Hospital, Ankara, Turkey
    Pediatr Dermatol 24:151-4. 2007
    A pityriasis rubra pilaris-like eruption has been described in patients with dermatomyositis. We describe an 11-year-old girl with dermatomyositis who had additional clinical findings of pityriasis rubra pilaris...
  10. ncbi Pityriasis rubra pilaris: an unusual cutaneous complication of AIDS
    R A Bonomo
    Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA
    Am J Med Sci 314:118-21. 1997
    b>Pityriasis rubra pilaris is an uncommon hyperkeratotic, papulosquamous disorder that has been reported in patients infected by HIV. We recount a case of pityriasis rubra pilaris in an HIV-seropositive man...
  11. doi Successful treatment of pityriasis rubra pilaris (type 1) under combination of infliximab and methotrexate
    Dietrich Barth
    Department of Dermatology, Venereology and Allergy, University of Leipzig, Philipp Rosenthal Strasse 23, Germany
    J Dtsch Dermatol Ges 7:1071-4. 2009
    b>Pityriasis rubra pilaris (PRP) is often difficult to treat. A 65-year-old women presented with a two week history of widespread erythroderma and scaling with areas of sparing (nappes claires)...
  12. ncbi Atypical pityriasis rubra pilaris associated with arthropathy and osteoporosis: a case report with 15-year follow-up
    Fiona D Behr
    Section of Dermatology, University of Arizona College of Medicine, Tucson, Arizona, USA
    Pediatr Dermatol 19:46-51. 2002
    b>Pityriasis rubra pilaris (PRP) is an idiopathic papulosquamous disease that clinically presents with palmoplantar keratoderma and follicular hyperkeratotic papules that coalesce into scaly erythematous plaques...
  13. ncbi Pityriasis rubra pilaris in a HIV-positive patient (Type 6 PRP)
    Dipankar De
    Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Skinmed 7:47-50. 2008
    ..Considering the atypical cutaneous findings, the clinical possibility of pityriasis rubra pilaris (human immunodeficiency virus [HIV]-associated type 6 PRP) was considered...
  14. ncbi (Juvenile) Pityriasis rubra pilaris
    Virendra N Sehgal
    Dermato Venereology Skin VD Centre, Sehgal Nursing Home, Delhi, India in
    Int J Dermatol 45:438-46. 2006
  15. ncbi Pityriasis rubra pilaris and hypothyroidism. Efficacy of thyroid hormone replacement therapy in skin recovery
    V Orlandini
    Br J Dermatol 156:606-7. 2007
  16. ncbi Adult onset pityriasis rubra pilaris
    Virendra N Sehgal
    Dermato Venereology Skin VD Centre, Sehgal Nursing Home, Delhi, India
    Indian J Dermatol Venereol Leprol 74:311-21. 2008
    b>Pityriasis rubra pilaris (PRP) has always been an intriguing topic ever since its inception...
  17. doi Type III juvenile pityriasis rubra pilaris: a successful treatment with infliximab
    M Ruzzetti
    J Eur Acad Dermatol Venereol 22:117-8. 2008
  18. ncbi A case of pityriasis rubra pilaris associated with sacroileitis and autoimmune thyroiditis
    U Gul
    J Eur Acad Dermatol Venereol 22:889-90. 2008
  19. ncbi Non-acne dermatologic indications for systemic isotretinoin
    Melih Akyol
    School of Medicine of Cumhuriyet University, Sivas, Turkey
    Am J Clin Dermatol 6:175-84. 2005
    ..Diseases such as psoriasis, pityriasis rubra pilaris, condylomata acuminata, skin cancers, rosacea, hidradenitis suppurativa, granuloma annulare, lupus ..
  20. ncbi Pityriasis rubra pilaris
    Katherine L White
    Ronald O Perelman Department of Dermatology, New York University, USA
    Dermatol Online J 9:6. 2003
    b>Pityriasis rubra pilaris is a chronic, papulosquamous dermatosis of unclear etiology. The case of a 61-year-old man with pityriasis rubra pilaris is presented...
  21. ncbi Pityriasis rubra pilaris in children
    Dawn S Allison
    Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
    J Am Acad Dermatol 47:386-9. 2002
    b>Pityriasis rubra pilaris (PRP) is an uncommon dermatosis in children. Few long-term studies on the treatment and prognosis of PRP in children have been performed.
  22. ncbi [Pityriasis rubra pilaris. Case reports and review of the literature]
    S Artik
    Universitäts Hautklinik, Heinrich Heine Universitat Dusseldorf
    Hautarzt 54:858-63. 2003
    Various treatment options for pityriasis rubra pilaris (PRP) are evaluated and new aspects of the pathogenesis are reviewed.with. Furthermore, 3 cases of adult onset PRP (type I), treated with acitretin, are presented.
  23. ncbi Clinical improvement of pityriasis rubra pilaris with combination etanercept and acitretin therapy
    Kristy F Davis
    Arch Dermatol 143:1597-9. 2007
  24. ncbi Fumaric acid esters therapy: a new treatment modality in pityriasis rubra pilaris?
    B Coras
    Br J Dermatol 152:388-9. 2005
  25. ncbi Tinea versicolor mimicking pityriasis rubra pilaris
    Matthew J Darling
    Department of Surgery, Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, Texas, USA
    Cutis 75:265-7. 2005
    ..We recount a case of tinea versicolor that mimicked type I (classic adult) pityriasis rubra pilaris. A 54-year-old white man reported a 20-year history of a recurrent pruritic eruption that had marginally ..
  26. ncbi Paraneoplastic pityriasis rubra pilaris in association with bronchogenic carcinoma
    Ann Maree Kurzydlo
    Department of Dermatology, Royal Newcastle Hospital, Newcastle, New South Wales, Australia
    Australas J Dermatol 45:130-2. 2004
    b>Pityriasis rubra pilaris (PRP) is an uncommon dermatosis occasionally reported in association with an underlying malignancy...
  27. ncbi Familial pityriasis rubra pilaris (adult classic-I): a report of three cases in a single family
    Virendra N Sehgal
    The Dermato Venereology Skin VD Center, Sehgal Nursing Home, Azadpur, Subzi Mandi, A 6 Panchwati, Delhi, India
    Skinmed 1:161-4. 2002
  28. pmc A review of pityriasis rubra pilaris and rheumatologic associations
    Happy Chan
    Department of Internal Medicine, University of California, Davis, USA
    Clin Dev Immunol 11:57-60. 2004
    b>Pityriasis rubra pilaris (PRP) is a rare group of hyperkeratotic, papulosquamous disease that can be acquired or inherited. There have been reported cases of rheumatologic associations, mainly arthritis and dermatomyositis...
  29. ncbi Merkel cell carcinoma and multiple cutaneous squamous cell carcinomas in a patient with pityriasis rubra pilaris
    Nghi T Huynh
    Department of Dermatology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, New South Wales, Australia
    Australas J Dermatol 43:48-51. 2002
    ..cell carcinoma (MCC) and multiple cutaneous squamous cell carcinomas (SCC) occurring on a background of pityriasis rubra pilaris. At the time of initial diagnosis and treatment for upper limb MCC, axillary nodal metastases were ..
  30. ncbi [Infectious risk]
    E Calabuig
    Unidad de Enfermedades Infecciosas, Hospital Universitario La Fe, Valencia, Espana
    Actas Dermosifiliogr 99:14-22. 2008
    ..inflammatory dermatitis and systemic diseases with skin expression, such as severe atopic dermatitis, pityriasis rubra pilaris, pyoderma gangrenosum, cutaneous sarcoidosis, Adult Still's disease, inverted acne and refractory graft -..
  31. ncbi Neonatal and infantile erythroderma: a clinical and follow-up study of 42 cases
    Muhsin A A Al-Dhalimi
    Department of Dermatology, College of Medicine, University of Kufa, Kufa, Iraq
    J Dermatol 34:302-7. 2007
    ..4%, atopic dermatitis in 14.3%, different types of Ichthyoses in 31.5%, psoriasis in 4.7%, pityriasis rubra pilaris in 2.4%, Staphylococcal scalded skin syndrome in 7.14%, Netherton syndrome in 4...
  32. doi Generalized leukaemia cutis from a small cell variant of T-cell prolymphocytic leukaemia presenting with exfoliative dermatitis
    Ki Heon Jeong
    Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea
    Acta Derm Venereol 89:509-12. 2009
    ..He had been treated with oral retinoids, steroids, and phototherapy for the diagnoses of drug eruption, pityriasis rubra pilaris, and exfoliative dermatitis at other hospitals...
  33. doi Pityriasis rubra pilaris in association with laryngeal carcinoma
    T Batinac
    Department of Dermatovenerology, University Hospital Center Rijeka, Rijeka, Croatia
    Clin Exp Dermatol 34:e917-9. 2009
    b>Pityriasis rubra pilaris (PRP) is a rare group of hyperkeratotic, papulosquamous diseases that can be acquired or inherited. Cases of PRP associated with malignancy have been rarely reported...
  34. ncbi HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes
    Sari Suomela
    Department of Dermatology, Helsinki University Central Hospital, Helsinki, Finland
    J Invest Dermatol 121:1360-4. 2003
    ..Compared to psoriasis, HCR protein had a different distribution in chronic dermatitis, pityriasis rubra pilaris, mycosis fungoides, and chronic skin ulcers...
  35. doi [What's new in pediatric dermatology?]
    J Mazereeuw-Hautier
    Service de Dermatologie, CHU Purpan, Toulouse, France
    Ann Dermatol Venereol 136:S426-35. 2009
    ..The literature in 2009 also contains studies on Lyell syndrome, Kawasaki disease, vitiligo, psoriasis, pityriasis rubra pilaris, urticaria and alopecia areata.
  36. ncbi Pityriasis rubra pilaris and focal acantholytic dyskeratosis
    P Cowen
    Monash Medical Centre, Clayton, Victoria, Australia
    Australas J Dermatol 38:40-1. 1997
    ..Clinically the eruption evolved to erythroderma with typical features of pityriasis rubra pilaris. On review of the histology, changes consistent with this diagnosis were also present in addition to the ..
  37. ncbi Living with pityriasis rubra pilaris
    Lorna Roberts
    Dermatol Nurs 17:452-3. 2005
  38. pmc Pityriasis rubra pilaris presenting with an abnormal autoimmune profile: two case reports
    Stamatis Gregoriou
    University of Athens Medical School, Department of Dermatology, Athens, Greece
    J Med Case Reports 3:123. 2009
    b>Pityriasis rubra pilaris is an uncommon inflammatory and hyperproliferative dermatosis of juvenile or adult onset. The etiology of the disease is still unknown.
  39. ncbi Infliximab in dermatological treatment: beyond psoriasis
    Dimitris Rigopoulos
    University of Athens, Department of Dermatology, A Sygros Hospital, 5 Ionos Dragoumi Street, Athens 16121, Greece
    Expert Opin Biol Ther 8:123-33. 2008
    ..inflammatory dermatoses as well as systemic diseases involving the skin such as severe atopic dermatitis, pityriasis rubra pilaris, pyoderma gangrenosum and cutaneous sarcoidosis...
  40. ncbi Pityriasis rubra pilaris in association with hepatitis A
    Teoman Erdem
    Department of Dermatology, Ataturk University, Turkey
    Saudi Med J 27:1421-2. 2006
  41. ncbi Type II adult-onset pityriasis rubra pilaris successfully treated with intravenous immunoglobulin
    A C Kerr
    Br J Dermatol 156:1055-6. 2007
  42. ncbi Extracorporeal photochemotherapy for the treatment of exanthematic pityriasis rubra pilaris
    H A Haenssle
    Department of Dermatology, Georg August University Goettingen, Germany
    Clin Exp Dermatol 29:244-6. 2004
    b>Pityriasis rubra pilaris (PRP) is a rare papulosquamous skin disease of unknown aetiology that has been categorized into five clinical types based on age at onset, cutaneous features and prognosis...
  43. ncbi Transient eruptive seborrhoeic keratoses associated with erythrodermic pityriasis rubra pilaris
    M T Sahin
    Clin Exp Dermatol 29:554-5. 2004
  44. ncbi Pityriasis rubra pilaris
    Bethany Cook
    University of Minnesota, Twin Cities Medical School, USA
    Dermatol Nurs 17:456. 2005
  45. doi Where pityriasis versicolor and pica collide
    Ben G Tallon
    Arch Dermatol 144:813-4. 2008
  46. ncbi Protein-losing gastroenteropathy in a patient with pityriasis rubra pilaris
    Takamitsu Sato
    Digestion 75:98. 2007
  47. ncbi Oral pityriasis rubra pilaris
    Luis Edmundo Martinez Calixto
    Advanced Oral and Maxillofacial Pathology, Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, NY 14214, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:604-7. 2006
    b>Pityriasis rubra pilaris is a chronic, papulosquamous dermatosis of unknown etiology. Oral mucosal involvement of this condition is rare with only 3 previously reported cases in the English literature...
  48. doi Pityriasis rubra pilaris--a retrospective single center analysis over eight years
    Astrid Gemmeke
    Department of Dermatology and Allergology, Dresden Friedrichstadt Hospital, Dresden, Germany
    J Dtsch Dermatol Ges 8:439-44. 2010
    b>Pityriasis rubra pilaris (PRP) is a rare papulosquamous dermatosis. We evaluated evaluate co-morbidities, complications, and outcome of treatment regimens.
  49. ncbi The relationship between pityriasis rubra pilaris and inflammatory arthritis: case report and response of the arthritis to anti-tumor necrosis factor immunotherapy
    P G Conaghan
    University of Leeds, UK
    Arthritis Rheum 42:1998-2001. 1999
    b>Pityriasis rubra pilaris (PRP) refers to a group of erythematous, scaling dermatologic conditions that have been associated with seronegative arthritis...
  50. doi Peripheral blood findings in erythrodermic patients: importance for the differential diagnosis of Sézary syndrome
    Arielle R Nagler
    School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Am Acad Dermatol 66:503-8. 2012
    ..cutaneous T-cell lymphoma can mimic a number of nonmalignant disorders with erythroderma, including pityriasis rubra pilaris, psoriasis, atopic dermatitis, and graft-versus-host disease...
  51. pmc Oral alitretinoin for the treatment of recalcitrant pityriasis rubra pilaris
    Laurenz Schmitt
    Dermatology Clinic, Clinical Centre of the City of Ludwigshafen, Ludwigshafen am Rhein, Germany
    Case Rep Dermatol 3:85-8. 2011
    Treatment of pityriasis rubra pilaris is still challenging...
  52. ncbi Type I pityriasis rubra pilaris: upregulation of tumor necrosis factor alpha and response to adalimumab therapy
    Yao Hua Zhang
    Department of Dermatology and Skin Science and Pathology and Laboratory Medicine, University of Bristish Columbia, Vancouver, BC
    J Cutan Med Surg 14:185-8. 2010
    b>pityriasis rubra pilaris (PRP) has unknown etiology and is often refractory to conventional therapies.
  53. ncbi Pityriasis rubra pilaris in a mother and two daughters
    M A Thomson
    Br J Dermatol 157:202-4. 2007
  54. ncbi Photoaggravated pityriasis rubra pilaris
    G Evangelou
    Photobiology Unit, Dermatological Sciences, University of Manchester, Hope Hospital, Manchester, UK
    Photodermatol Photoimmunol Photomed 21:272-4. 2005
    b>Pityriasis rubra pilaris (PRP) is a rare papulosquamous condition with an estimated incidence of one in 35,000 to one in 50,000...
  55. doi Off-label use of fumarate therapy for granulomatous and inflammatory skin diseases other than psoriasis vulgaris: a retrospective study
    A Klein
    Department of Dermatology, University Hospital Regensburg, Regensburg, Germany
    J Eur Acad Dermatol Venereol 26:1400-6. 2012
    ..However, a number of studies and case reports indicate their efficacy in the treatment of further inflammatory skin disorders or granulomatous skin diseases...
  56. ncbi Successful use of etanercept in type I pityriasis rubra pilaris
    D Seckin
    Br J Dermatol 158:642-4. 2008
  57. doi Pityriasis rubra pilaris-like reaction induced by imatinib
    A Plana
    Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autonoma de Barcelona, Badalona, Spain
    Clin Exp Dermatol 38:520-2. 2013
    ..We report a case of a pityriasis rubra pilaris (PRP)-like eruption associated with this drug...
  58. doi A case of pityriasis rubra pilaris associated with membranous nephropathy
    Chin Yun Lin
    Departments of Dermatology Nephrology, Canterbury District Health Board, Christchurch, New Zealand
    Australas J Dermatol 54:e1-3. 2013
    b>Pityriasis rubra pilaris (PRP) is a rare idiopathic dermatosis which may be associated with autoimmune diseases, HIV infection, and internal malignancies. Its association with renal diseases is, however, much less recognized...
  59. ncbi New-onset vitiligo during long-term, stable infliximab treatment of pityriasis rubra pilaris
    Adam R Mattox
    Department of Dermatology, Saint Louis University School of Medicine, St Louis, MO, USA
    J Drugs Dermatol 12:217-9. 2013
    ..the presentation of infliximab-induced vitiligo in a patient using it for long-term treatment of stable pityriasis rubra pilaris. The patient was initiated and titrated to a stable dose of infliximab totaling 27 months' duration...
  60. doi Extremely high parathyroid hormone concentrations associated with pityriasis rubra pilaris and monoclonal gammopathy of unknown significance: a clinical dilemma
    Mine Durusu Tanriover
    Hacettepe University Faculty of Medicine, Department of Internal Medicine, Ankara, Turkey
    Bone 51:847-50. 2012
    ..The extremely high PTH concentrations were not only due to assay interference, but also secondary hyperparathyroidism, which was evident by the decrease in PTH concentrations with calcium and vitamin D treatments...
  61. ncbi Lipoid proteinosis: report of a possible localized form on both hands and wrists
    Sindy Hu
    Departments of Dermatology and Pathology, Chang Gung University School of Medicine, Chang Gung Memorial Hospital, 199 Tun Hwa North Road, Tao Yuan, Taipei 105, Taiwan
    Int J Dermatol 44:408-10. 2005
    ..A skin biopsy was taken for histopathologic and ultrastructural studies under the clinical impression of pityriasis rubra pilaris. Microscopically, homogeneous perivascular deposits of hyaline-like material were seen in the papillary ..
  62. doi A systematic review of the literature on the treatment of pityriasis rubra pilaris type 1 with TNF-antagonists
    G Petrof
    St John s Institute of Dermatology, Guy s and St Thomas NHS Foundation Trust, London, UK
    J Eur Acad Dermatol Venereol 27:e131-5. 2013
    Adult pityriasis rubra pilaris (PRP) type 1 is a rare chronic papulosquamous disorder with clinical and histological parallels with psoriasis...
  63. doi [Pityriasis rubra pilaris]
    U Wollina
    Klinik für Dermatologie und Allergologie, Krankenhaus Dresden Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr 41, 01067 Dresden
    Hautarzt 63:655-61; quiz 662. 2012
    b>Pityriasis rubra pilaris is an inflammatory papulosquamous skin disease of unknown etiology. Incidence rates vary between 1:5,000-1:50,000. Six subtypes are differentiated on clinical background...
  64. ncbi Diseases associated with hidranitis suppurativa: part 2 of a series on hidradenitis
    Noah Scheinfeld
    Weill Cornell Medical College, New York, NY, USA
    Dermatol Online J 19:18558. 2013
    ..b>Pityriasis rubra pilaris, in particular Type VI related to HIV, has a relationship more commonly with acne conglobata, but with HS ..
  65. ncbi Response of juvenile circumscribed pityriasis rubra pilaris to topical tazarotene treatment
    Daniela Karimian-Teherani
    Division of General Dermatology, Medical University of Vienna, Wahringer Gurtel, Vienna, Ausria
    Pediatr Dermatol 25:125-6. 2008
    We report juvenile circumscribed pityriasis rubra pilaris (type IV) in a 12-year-old Afghani girl in whom local therapy with tazarotene led to rapid, sustained remission...
  66. doi Infliximab monotherapy as first-line treatment for adult-onset pityriasis rubra pilaris: case report and review of the literature on biologic therapy
    Hansgeorg Muller
    Department of Dermatology and Venerology, Innsbruck Medical University, Innsbruck, Austria
    J Am Acad Dermatol 59:S65-70. 2008
    b>Pityriasis rubra pilaris (PRP) is a rare, chronic papulosquamous disorder of unknown etiology that often progresses to disabling palmoplantar keratoderma and erythroderma...
  67. doi Therapeutic hotline. Treatment of pityriasis rubra pilaris with etanercept
    Rita Guedes
    Dermatology Department, Centro Hospitalar de Vila Nova de Gaia, Vila Nova de Gaia Dermatology Department Clínica Laser Belém, Lisbon, Portugal
    Dermatol Ther 24:285-6. 2011
    b>Pityriasis rubra pilaris (PRP) or Devergie's disease is a chronic and rare papulosquamous disorder of unknown etiology characterized by reddish orange scaly plaques, palmoplantar keratoderma, and keratotic follicular papules...
  68. ncbi Pityriasis rubra pilaris sensitive to narrow band-ultraviolet B light therapy
    Irene J Vergilis-Kalner
    Section of Dermatology, University of Chicago, Chicago, IL 60637, USA
    J Drugs Dermatol 8:270-3. 2009
    b>Pityriasis rubra pilaris (PRP) is a rare skin condition which typically presents in adults as red-orange plaques with islands of sparing, perifollicular keratotic papules, waxy palmoplantar keratoderma, and erythema with fine, diffuse ..
  69. ncbi Letter: Adenocarcinoma of the lung associated with pityriasis rubra pilaris
    Cara B Garretson
    Northwestern Memorial Physicians Group, Chicago, Illinois
    Dermatol Online J 17:14. 2011
    We describe a case of pityriasis rubra pilaris refractory to conventional treatment, found to be associated with an unrecognized primary adenocarcinoma of the lung...
  70. doi A case of pityriasis rubra pilaris with associated focal acantholytic dyskeratosis complicated by Kaposi's varicelliform eruption
    Gulsun Erdag
    Section of Dermatopathology, Department of Pathology, University of Virginia, Charlottesville, VA, USA
    J Cutan Pathol 38:919-22. 2011
    The clinical and histopathological diagnosis of pityriasis rubra pilaris (PRP) can be difficult because clinical findings are often subtle in early stages, and microscopic findings can overlap with those of other skin diseases...
  71. doi Pityriasis rubra pilaris: the clinical context of acantholysis and other histologic features
    Christine J Ko
    Department of Dermatology, Yale University School of Medicine, New Haven, CT, USA
    Int J Dermatol 50:1480-5. 2011
    Acantholysis has been described in biopsies of pityriasis rubra pilaris (PRP), but this has not been emphasized in the dermatology literature...
  72. doi [Pityriasis rubra pilaris after vaccination]
    B Naciri Bennani
    Service de Dermatologie, Hopitaux de Brabois, bâtiment Philippe Canton, 4, rue du Morvan, 54500, Vandoeuvre les Nancy, France
    Ann Dermatol Venereol 138:753-6. 2011
    b>Pityriasis rubra pilaris (PRP) following vaccination is rarely described in the literature. We report a case of PRP occurring two weeks after measles-mumps-rubella (MMR) vaccination.
  73. doi Clinical investigation of acitretin in children with severe inherited keratinization disorders in China
    Xi Bao Zhang
    Department of Dermatology, Guangzhou Institute of Dermatology, Guangzhou, PR of China
    J Dermatolog Treat 19:221-8. 2008
    ..Investigation into the clinical efficacy, side effects and safety of oral acitretin on severe inherited disorders of keratinization in children...
  74. ncbi Skin biopsy and psoriasis
    M T Rahman
    Department of Pathology, Ibrahim Medical College and Consultant Grade I, Histopathology, BIHS, Mirpur, Dhaka, Bangladesh tahminurrahman yahoo com
    Mymensingh Med J 19:353-9. 2010
    ..12%). Ashy dermatosis 3(9.09%), Nevus 2(6.06%) and corn, hemangioma, prurigo simplex, pityriasis rubra pilaris (PRP), dermatofibroma, 1(3.03%) each...
  75. doi PRP with subcorneal acantholysis: case report and review
    Anita Sebastian
    Department of Pathology, Drexel College of Medicine, Philadelphia, PA 19130, USA
    J Cutan Pathol 37:99-101. 2010
    Although the clinical findings of pityriasis rubra pilaris (PRP) are striking, the microscopic diagnosis can be difficult because changes can be subtle and can overlap with other skin diseases...
  76. doi Bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis and corneal perforation in a patient with pityriasis rubra pilaris
    Anna S Kitzmann
    Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
    Cornea 27:1212-4. 2008
    To report a case of bilateral herpes simplex keratitis with unilateral secondary bacterial keratitis resulting in corneal perforation in a patient with pityriasis rubra pilaris.
  77. doi Genitogluteal porokeratosis: 10 years to make the diagnosis!
    Joelle Malek
    Department of Dermatology, American University of Beirut Medical Center, Beirut, Lebanon
    Am J Dermatopathol 31:604-6. 2009
    ..Despite multiple skin biopsies, the lesions were misdiagnosed as psoriasis, lichen simplex chronicus, pityriasis rubra pilaris, and mycosis fungoides, until the last biopsy revealed findings characteristic of porokeratosis...
  78. ncbi Further clinical evidence for involvement of bacterial superantigens in juvenile pityriasis rubra pilaris (PRP): report of two new cases
    Matthias Möhrenschlager
    Pediatr Dermatol 19:569. 2002
  79. ncbi Advocacy and hope for the patient with pityriasis rubra pilaris
    Kathy J Nunemacher
    St Luke s Hospital and Health Network, Bethlehem, PA, USA
    Dermatol Nurs 20:375-7. 2008
    b>Pityriasis rubra pilaris (PRP) is a rare skin disease that can cause severe physical and psychological manifestations...
  80. doi Juvenile pityriasis rubra pilaris: report of 28 cases in Taiwan
    Chao Chun Yang
    Department of Dermatology, College of Medicine, National Cheng Kung University, Tainan, Taiwan
    J Am Acad Dermatol 59:943-8. 2008
    b>Pityriasis rubra pilaris (PRP) is a papulosquamous dermatosis uncommon in juveniles. Large-scale studies are limited, especially from Asian countries.
  81. ncbi Pityriasis rubra pilaris successfully treated with infliximab
    Diana P Ruiz-Genao
    Acta Derm Venereol 87:552-3. 2007
  82. ncbi Retinoids in disorders of keratinization: their use in adults
    R Happle
    Department of Dermatology, University of Nijmegen, The Netherlands
    Dermatologica 175:107-24. 1987
    ..Papillon-Lefèvre syndrome, erythrokeratodermia variabilis, verrucous epidermal nevi, Darier disease and pityriasis rubra pilaris. In patients with Darier disease it is wise to begin with a relatively low dosage of 0...
  83. ncbi [Acute juvenile pityriasis rubra pilaris in a 2-year-old child]
    Adina Thölke
    Klinik fur Dermatologie, Venerologie und Allergologie am Klinikum Mannheim gGmbH, Universitätsklinikum der Ruprecht Karls Universität Heidelberg
    J Dtsch Dermatol Ges 2:357-9. 2004
    b>Pityriasis rubra pilaris (PRP) is a rare idiopathic erythematosquamous disorder...
  84. ncbi Pityriasis rubra pilaris as the initial presentation of renal cell carcinoma?
    R J Batchelor
    Clin Exp Dermatol 30:442-3. 2005
  85. pmc Erythroderma: a clinical study of 97 cases
    Maryam Akhyani
    Department of Dermatology, Tehran University of Medical Sciences, Razi Hospital, Vahdate Eslami Sq 11966, Tehran, Iran
    BMC Dermatol 5:5. 2005
    ..Erythroderma is a rare skin disorder that may be caused by a variety of underlying dermatoses, infections, systemic diseases and drugs...
  86. ncbi Circumscribed juvenile pityriasis rubra pilaris
    A W Arnold
    Department of Dermatology, University of Basel, Kantonsspital Basel, Petersgraben 4, CH 4031 Basel, Switzerland
    J Eur Acad Dermatol Venereol 18:705-7. 2004
    We report the case of a 20-year-old woman with a 10-year history of circumscribed juvenile-onset pityriasis rubra pilaris (PRP, type IV)...
  87. ncbi [Pityriasis rubra pilaris. A characteristic but rare skin disease]
    Mikkel Høiberg
    Odense Universitetshospital, Dermato Venerologisk Afdeling I
    Ugeskr Laeger 166:2909-10. 2004
  88. ncbi Oral cyclosporine in the treatment of inflammatory and noninflammatory dermatoses. A clinical and immunopathologic analysis
    A K Gupta
    Department of Dermatology, University of Michigan Medical School, Ann Arbor
    Arch Dermatol 126:339-50. 1990
    ..Little or no response was noted in both patients with sarcoidosis, all 3 patients with pityriasis rubra pilaris, 5 of 6 patients with vitiligo, 1 patient with pemphigus foliaceous, and 1 with pemphigus vulgaris...
  89. ncbi Spontaneous clinical improvement in HIV-associated follicular syndrome
    C Blasdale
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    Clin Exp Dermatol 29:480-2. 2004
    ..described a distinctive triad of nodulocystic acne, striking follicular spines and an eruption resembling pityriasis rubra pilaris (PRP) in HIV-positive patients...
  90. ncbi Juvenile pityriasis rubra pilaris
    Joshua E Lane
    Pediatr Dermatol 21:512-3. 2004
  91. ncbi Inflammatory myopathy in a patient with cutaneous findings of pityriasis rubra pilaris: a case of Wong's dermatomyositis
    Roberto Caporali
    Department of Rheumatology, IRCCS Policlinico, San Matteo Hospital, University of Pavia, Piazzale Golgi 2, 27100, Pavia, Italy
    Clin Rheumatol 23:63-5. 2004
    We report the case of a 46-year-old woman presenting cutaneous lesions similar to those of pityriasis rubra pilaris, characterized by diffuse scaling erythroderma and palmoplantar keratoderma; skin biopsy showed follicular hyperkeratosis ..
  92. ncbi Papulosquamous diseases in the elderly
    Robert A Norman
    Department of Internal Medicine, Division of Dermatology, Nova South eastern Medical Center, Tampa, Florida, USA
    Dermatol Ther 16:231-42. 2003
    ..The authors also provide important laboratory exams that can be performed and can help guide diagnosis, as well as differential diagnosis and treatment options...
  93. ncbi [Paraneoplastic pityriasis rubra pilaris in metastatic adenocarcinoma without diagnosable primary]
    C Kloos
    Klinik für Innnere Medizin II, Germany
    Dtsch Med Wochenschr 127:437-40. 2002
    ..After continued spreading of these cutaneous lesions, she was admitted to hospital, presenting with a generalised desquamating erythrodermia and marked pruritus...
  94. ncbi Acute juvenile pityriasis rubra pilaris: a superantigen mediated disease?
    I Betlloch
    Department of Dermatology, General Universitary Hospital, Alicante, Spain
    Pediatr Dermatol 18:411-4. 2001
    Juvenile acute pityriasis rubra pilaris (JAPRP) is a form of pityriasis rubra pilaris (PRP) with particular clinical characteristics and course. It is usually preceded by an infectious condition...
  95. ncbi Assessment of the clinical effect of topical tacalcitol on ichthyoses with retentive hyperkeratosis
    M Okano
    Department of Dermatology, Aizembashi Hospital, Osaka, Japan
    Dermatology 202:116-8. 2001
    ..demonstrated to produce beneficial clinical effects on epidermo-hyperproliferative disorders such as psoriasis and pityriasis rubra pilaris. However, the efficacy of the agent has not been elucidated in retentive hyperkeratotic disorders.
  96. ncbi Corneocytes in scaly parakeratotic diseases
    M Amer
    Department of Dermatology, University of Zagazig, Faculty of Medicine, Egypt
    Int J Dermatol 35:417-21. 1996
    ....
  97. ncbi Photosensitive pityriasis rubra pilaris
    H E Iredale
    Royal Victoria Infirmary, Department of Dermatology, London, UK
    Clin Exp Dermatol 31:36-8. 2006
    Exacerbation of pityriasis rubra pilaris (PRP) with ultraviolet exposure is well recognized. However, the initial presentation of PRP in a photoexposed distribution is infrequently reported, and only rarely confirmed with phototesting...
  98. ncbi Pityriasis rubra pilaris, type 1
    Alexandria V Booth
    Department of Dermatology, New York University School of Medicine, USA
    Dermatol Online J 11:9. 2005
    ..Clinical and histopathologic examination were consistent with pityriasis rubra pilaris, and treatment consisted of acitretin and narrow-band ultraviolet B phototherapy...
  99. ncbi Pityriasis rubra pilaris, type IV
    Jennifer Bragg
    Department of Dermatology, New York University School of Medicine, USA
    Dermatol Online J 11:14. 2005
    ..Clinical and histologic findings were consistent with a diagnosis of pityriasis rubra pilaris (PRP), type IV (circumscribed juvenile)...
  100. ncbi Juvenile onset classical pityriasis rubra pilaris: every patient may not require systemic therapy
    Naeem Raza
    Department of Dermatology, Combined Military Hospital, Abbottabad
    J Coll Physicians Surg Pak 17:564-5. 2007
    Juvenile onset classical Pityriasis Rubra Pilaris (PRP), although rare, is the most common presentation of PRP in children. It has good prognosis and resolution over a few months...
  101. ncbi Recurrence of classical juvenile pityriasis rubra pilaris in adulthood: report of a case
    J B Hong
    Br J Dermatol 157:842-4. 2007

Research Grants2

  1. WORKSHOP ON ORAL RETINOIDS IN DERMATOLOGICAL DISEASE
    John Strauss; Fiscal Year: 1980
    ..The diseases that have been treated include cystic and conglobate acne, psoriasis, pityriasis rubra pilaris, Darier's disease, lamellar ichthyosis, congenital ichthyosiform erythroderma, and epidermolytic ..
  2. PATHOPHYSIOLOGY & CHEMOTHERAPY IN PSORIASIS AND CANCER
    Gerald Weinstein; Fiscal Year: 1980
    ..both in vivo and in vitro, in a spectrum of proliferative cutaneous diseases that include psoriasis, pityriasis rubra pilaris, skin cancer and cutaneous metastases of internal malignancies taking advantage of their easy ..