- Gadolinium--a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?
Department of Nephrology, General Hopsital of Wiener Neustadt, A 2700 Wiener Neustadt, Austria
Nephrol Dial Transplant 21:1104-8. 2006
- Basophil recruitment and activation in inflammatory skin diseases
Department of Dermatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
Allergy 66:1107-13. 2011
..However, basophil infiltration into the tissues in human skin diseases remains to be addressed.
- Dermoscopy of pigmented skin lesions: results of a consensus meeting via the Internet
Department of Dermatology, Second University of Naples, Italy
J Am Acad Dermatol 48:679-93. 2003
..There is a need for better standardization of the dermoscopic terminology in assessing pigmented skin lesions...
- Nephrogenic systemic fibrosis: suspected causative role of gadodiamide used for contrast-enhanced magnetic resonance imaging
Department of Nephrology, Copenhagen University Hospital at Herlev, DK 2730 Herlev, Denmark
J Am Soc Nephrol 17:2359-62. 2006
..No other exposure/event than gadodiamide that was common to more than a minority of the patients could be identified. These findings indicate that gadodiamide plays a causative role in nephrogenic systemic fibrosis...
- Improved discriminative and evaluative capability of a refined version of Skindex, a quality-of-life instrument for patients with skin diseases
M M Chren
Dermatology Service, Cleveland Veterans Affairs Medical Center, Ohio, USA
Arch Dermatol 133:1433-40. 1997
..To improve Skindex, a dermatologic quality-of-life instrument...
- Dermatological phenotype in Costello syndrome: consequences of Ras dysregulation in development
D H Siegel
Department of Dermatology and Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road TBRC, 2nd Floor, Suite C2010, Milwaukee, WI 53226, USA
Br J Dermatol 166:601-7. 2012
..Costello syndrome (CS) is a RASopathy caused by mutations in the HRAS gene, a key regulator of signal transduction...
- Antioxidant activity, lipid peroxidation and skin diseases. What's new
Cutaneous Physiopathology Laboratory, San Gallicano Dermatological Institute, 25 A Via S Gallicano, 00153 Rome, Italy
J Eur Acad Dermatol Venereol 17:663-9. 2003
..are polyunsaturated fatty acids and theirs oxidation products, have a central role in the induction of some skin diseases, such as psoriasis or acne, has indicated new links between free radicals and skin inflammation...
- Notch signaling: its role in epidermal homeostasis and in the pathogenesis of skin diseases
Department of Dermatology, Tohoku University Graduate School of Medicine, 1 1 Seiryo machi, Aoba ku, Sendai 980 8574, Japan
J Dermatol Sci 49:187-94. 2008
..Future efforts to further define how Notch controls cell proliferation and differentiation may lead to the application of Notch in new therapies for various skin diseases.
- Ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics among the tribal communities of North-West Frontier Province, Pakistan
Arshad Mehmood Abbasi
Department of Plant Sciences, Quaid i Azam University, Islamabad 45320, Pakistan
J Ethnopharmacol 128:322-35. 2010
The present investigation is an attempt to find out ethnopharmacological application of medicinal plants to cure skin diseases and in folk cosmetics.
- Photoprotective potential of strawberry (Fragaria × ananassa) extract against UV-A irradiation damage on human fibroblasts
Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Universita Politecnica delle Marche, Ancona, Italy
J Agric Food Chem 60:2322-7. 2012
..is known to induce discrete lesions in DNA and the generation of free radicals that lead to a wide array of skin diseases. Strawberry (Fragaria × ananassa) contains several polyphenols with strong antioxidant and anti-inflammatory ..
- Differential in situ expression of IL-17 in skin diseases
Department of Dermatology and Allergy, Technische Universität and Helmholtz Center Munich, Biedersteiner Straße 29, Munich, Germany
Eur J Dermatol 22:781-4. 2012
..Interleukin (IL)-17 is a key molecule for epithelial immunity and inflammation...
- Systemic ciclosporin and tacrolimus in dermatology
The Dermatology Center, University of Manchester, Hope Hospital, Salford, Manchester, UK
Dermatol Ther 20:239-50. 2007
..However, there are several case studies and anecdotal reports of the successful use of oral tacrolimus in various dermatoses. In this article we discuss the utility of systemic ciclosporin and tacrolimus in dermatology...
- Mechanisms of cutaneous toxicities to EGFR inhibitors
Mario E Lacouture
SERIES Clinic and Cancer Skin Care Program, Department of Dermatology, Northwestern University Feinberg School of Medicine, 676 North Saint Clair Suite 1600, Chicago, Illinois 60611, USA
Nat Rev Cancer 6:803-12. 2006
..There is an urgent need for an improved understanding of these toxicities to develop adequate staging systems and mechanistically driven therapies, and to ensure quality of life and consistent antineoplastic therapy...
- Photoageing: mechanism, prevention and therapy
Department of Dermatology, Boston University School of Medicine, 609 Albany Street, Boston, MA 02118 2394, USA
Br J Dermatol 157:874-87. 2007
..Such advances should not only allow for the improved appearance of skin in middle age and beyond, but also greatly reduce the accompanying burden of skin cancer...
- Measurement properties of Skindex-16: a brief quality-of-life measure for patients with skin diseases
M M Chren
Department of Dermatology, University of California at San Francisco, San Francisco, California, USA
J Cutan Med Surg 5:105-10. 2001
..An accurate, sensitive, but brief quality-of-life outcomes measure is needed for studies of dermatologic care...
- Cutaneous sarcoidosis occurring during anti-TNF-alpha treatment: report of two cases
Department of Dermatology, Amiens University Medical Centre, South Hospital, Amiens, France Florie Dhaille orange fr
Dermatology 220:234-7. 2010
..The biospies confirmed the diagnosis of a 'sarcoidosis-like' reaction. No systemic involvement was observed. Such cases of noninfectious granulomatous diseases occurring during anti-TNF-alpha therapy are becoming increasingly frequent...
- Folk phytotherapeutical plants from Maratea area (Basilicata, Italy)
Paolo Maria Guarrera
Museo Nazionale Arti e Tradizioni Popolari, Piazza Marconi 8 10, 00144 Rome, Italy
J Ethnopharmacol 99:367-78. 2005
..graeca (coughs) and Ceterach officinarum (malaria), while in the ethnoveterinary field, we have Pteridium aquilinum (wolf bites) and Spartium junceum (fractures of animal limbs)...
- Induction of GVHD-like skin disease by passively transferred CD8(+) T-cell receptor transgenic T cells into keratin 14-ovalbumin transgenic mice
Dermatology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
J Invest Dermatol 123:109-15. 2004
- Nephrogenic systemic fibrosis: risk factors and incidence estimation
Elizabeth A Sadowski
Department of Radiology, University of Wisconsin, Madison, WI 53792 3252, USA
Radiology 243:148-57. 2007
..To retrospectively review data in 13 patients with biopsy-confirmed nephrogenic systemic fibrosis (NSF), assess the associated risk factors, and report the incidence of NSF at the authors' institution...
- Neurological symptoms and natural course of xeroderma pigmentosum
Department of Neurology, Turku University Central Hospital, PB 52, 20521 Turku, Finland
Brain 131:1979-89. 2008
- A prospective study of arsenic exposure from drinking water and incidence of skin lesions in Bangladesh
Department of Health Studies, The University of Chicago, Illinois 60637, USA
Am J Epidemiol 174:185-94. 2011
..Chronic arsenic exposure from drinking water was associated with increased incidence of skin lesions, even at low levels of arsenic exposure (<100 μg/L)...
- Critical review of generic and dermatology-specific health-related quality of life instruments
Department of Dermatology, Erasmus MC, Rotterdam, The Netherlands
J Invest Dermatol 127:2726-39. 2007
The measurement of health-related quality of life (HRQOL) is increasingly important in patients with skin diseases. Despite the availability of a variety of instruments and new psychometric techniques, there is no consensus as to which ..
- Sarcoid-like granulomatosis in patients treated with tumor necrosis factor blockers: 10 cases
Claire Immediato Daïen
CHU Lapeyronie, Service d Immuno Rhumatologie, Montpellier, France
Rheumatology (Oxford) 48:883-6. 2009
..However, several cases of sarcoidosis have been diagnosed during anti-TNF therapy. Here, we report the largest series of sarcoid-like granulomatosis following TNF blocker treatment...
- Zebrafish: a model system to study heritable skin diseases
Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA
J Invest Dermatol 131:565-71. 2011
Heritable skin diseases represent a broad spectrum of clinical manifestations due to mutations in ∼500 different genes. A number of model systems have been developed to advance our understanding of the pathomechanisms of genodermatoses...
- Adverse effects of topical glucocorticosteroids
Ulrich R Hengge
Department of Dermatology, Heinrich Heine University Duesseldorf, Germany
J Am Acad Dermatol 54:1-15; quiz 16-8. 2006
..The authors provide an updated review of local and systemic adverse effects upon administration of topical corticosteroids, including the latest FDA report on the safety of such steroids in children...
- A randomized, double-blind placebo-controlled trial evaluating the effects of vitamin E and selenium on arsenic-induced skin lesions in Bangladesh
Wendy J Verret
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York 10032, USA
J Occup Environ Med 47:1026-35. 2005
..We sought to determine whether supplementation of vitamin E (alpha-tocopherol), selenium (L-selenomethionine), or their combination improves arsenical skin lesions...
- Gap junctions: basic structure and function
1Program in Genetics, Stony Brook University, Stony Brook, New York, USA
J Invest Dermatol 127:2516-24. 2007
..Here, we discuss the basic structure of gap junction channels and the function of connexin genes that have been associated with human disorders to explore the physiology of intercellular communication in skin...
- Revertant mosaicism in skin: natural gene therapy
Joey E Lai-Cheong
St John s Institute of Dermatology, Division of Genetics and Molecular Medicine, Floor 9 Tower Wing, King s College London Guy s Campus, London SE1 9RT, United Kingdom
Trends Mol Med 17:140-8. 2011
..This overview highlights the latest developments in revertant mosaicism and the translational implications germane to heritable skin disorders...
- Effects of epidermal growth factor receptor inhibitor-induced dermatologic toxicities on quality of life
Smita S Joshi
Skin and Eye Reactions to Inhibitors of Epidermal Growth Factor Receptor and Kinase SERIES Clinic and Cancer Skin Care Program, Department of Dermatology and Robert H Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
Cancer 116:3916-23. 2010
..By using a dermatology-specific questionnaire, the authors examined the effect of these toxicities on QoL...
- Frontiers in sebaceous gland biology and pathology
Christos C Zouboulis
Department of Dermatology, Dessau Medical Center, Dessau, Germany
Exp Dermatol 17:542-51. 2008
..These multiple homeostatic functions award the sebaceous gland the role 'brain of the skin' and the most important cutaneous endocrine gland...
- Cytochrome p450: a target for drug development for skin diseases
Department of Dermatology, University of Wisconsin, 1300 University Avenue, Madison, WI 53706, USA
J Invest Dermatol 123:417-25. 2004
..In addition, in some skin diseases, for example in psoriasis, many CYP are elevated...
- Managing treatment side effects in advanced breast cancer
CancerExpertise, Chicago, IL 60641 3228, USA
Semin Oncol Nurs 23:S23-30. 2007
..To compare and contrast the side-effect profiles of antineoplastic therapy options used in the treatment of metastatic breast cancer...
- Clinical signs, pathophysiology and management of skin toxicity during therapy with epidermal growth factor receptor inhibitors
Department of Dermatology, University Hospital, Katholieke Universiteit Leuven, Belgium
Ann Oncol 16:1425-33. 2005
..This review outlines the broad spectrum of cutaneous side-effects of EGFR inhibitors, discusses possible underlying mechanisms and provides practical guidelines for the management based on literature data and on personal experience...
- National athletic trainers' association position statement: skin diseases
Steven M Zinder
The University of North Carolina at Chapel Hill, USA
J Athl Train 45:411-28. 2010
..To present recommendations for the prevention, education, and management of skin infections in athletes...
- Microbiome and skin diseases
Patrick L J M Zeeuwen
Department of Dermatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Curr Opin Allergy Clin Immunol 13:514-20. 2013
This article reviews recent findings on the skin microbiome. It provides an update on the current understanding of the role of microbiota in healthy skin and in inflammatory and allergic skin diseases.
- Epidemiology of skin diseases in ethnic populations
Susan C Taylor
Skin of Color Center, St Luke s Roosevelt Hospital Center, 1090 Amsterdam Avenue, Suite 1l D, New York, NY 10025, USA
Dermatol Clin 21:601-7. 2003
..Many skin diseases are seemingly common to most of the ethnic populations, however, including blacks, Hispanics, Asians, and ..
- Synthesis and structure-activity relationships of skin ceramides
Department of Inorganic and Organic Chemistry, Charles University in Prague, Faculty of Pharmacy in Hradec Kralove, Heyrovskeho 1203, 50005 Hradec Kralove, Czech Republic
Curr Med Chem 17:2301-24. 2010
..Moreover, prominent skin diseases such as psoriasis and atopic dermatitis are associated with diminished ceramide levels and may be effectively ..
- Common burden of chronic skin diseases? Contributors to psychological distress in adults with psoriasis and atopic dermatitis
A W M Evers
Department of Medical Psychology, Radboud University Nijmegen Medical Center, 6500 HB Nijmegen, The Netherlands
Br J Dermatol 152:1275-81. 2005
Chronic skin diseases, such as atopic dermatitis and psoriasis, are known to affect quality of life by heightening psychological distress...
- Cutaneous manifestations in renal transplant recipients of Santiago, Chile
Department of Dermatology, Pontificia Universidad Catolica de Chile, Chile
Transplant Proc 41:3752-4. 2009
..These manifestations differ depending on the evaluated population. The objective of this study was to describe the prevalence of cutaneous manifestations among renal transplant recipients in Chile between 1979 and 2008...
- Community based study to compare the incidence and health services utilization pyramid for gastrointestinal, respiratory and dermal symptoms
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
BMC Health Serv Res 12:211. 2012
..The aim of this study was to describe the epidemiology and rate these three major symptom complexes in order to improve our understanding of the health burden imposed by these symptoms...
- Development of cutaneous sarcoidosis during treatment with tumour necrosis alpha factor antagonists
Department of Dermatology, Royal North Shore Hospital, St Leonards, NSW 2065, Australia
Australas J Dermatol 53:e87-90. 2012
..We present an unusual case of limited cutaneous sarcoidosis developing while the patient was on etanercept therapy, and a review of the current literature...
- Prevalence of skin disease among school children and adolescents in a Student Health Service Center in Hong Kong
W K Fung
Social Hygiene Service, Department of Health, Hong Kong
Pediatr Dermatol 17:440-6. 2000
..In this study, the differences in prevalence of skin diseases between these two groups are pointed out...
- Personal characteristics, therapy modalities and individual DNA repair capacity as predictive factors of acute skin toxicity in an unselected cohort of breast cancer patients receiving radiotherapy
German Cancer Research Center, Division of Clinical Epidemiology, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Radiother Oncol 69:145-53. 2003
..The influence of therapy modalities, personal characteristics and individual DNA repair capacity on the risk of acute skin toxicity was thus evaluated...
- Mast cells and immunological skin diseases
Department of Dermatology, School of Medicine, University of California Davis, Sacramento, CA 95816, USA
Clin Rev Allergy Immunol 33:144-55. 2007
..article reviews the literature on the role of this cell type in the pathogenesis of a number of immunological skin diseases, including contact dermatitis, atopic dermatitis, immunobullous disease, scleroderma, and chronic graft-vs...
- IL-21 in the pathogenesis and treatment of skin diseases
Dermatology Unit, Department of Internal Medicine, University of Rome Tor Vergata, Via Montpellier, 1, 00133 Rome, Italy
J Dermatol Sci 60:61-6. 2010
..Many of these activities are critically involved in the pathogenesis of several skin diseases such as psoriasis, atopic dermatitis, lupus erythematosus, and melanoma...
- Epidemiological pattern of tattoo skin disease: a potential general health indicator for cetaceans
Marie Françoise Van Bressem
Cetacean Conservation Medicine Group, CEPEC, Museo de Delfines, Pucusana, Lima 20, Peru
Dis Aquat Organ 85:225-37. 2009
..The epidemiological pattern of TSD may be an indicator of cetacean population health...
- Epidemiology of skin diseases in school children: a study from northern India
Department of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Pediatr Dermatol 20:470-3. 2003
..overcrowding, and poor standards of hygiene are important factors accounting for the distribution of skin diseases in developing countries such as India...
- Beneficial role of curcumin in skin diseases
Rajesh L Thangapazham
Uniformed Services University of Health Sciences, Bethesda, MD, USA
Adv Exp Med Biol 595:343-57. 2007
..to explore its use in various disorders like tumors of skin, colon, duodenum, pancreas, breast and other skin diseases. This chapter reviews the data on the use of curcumin for the chemoprevention and treatment of various skin ..
- Clinical optical coherence tomography combined with multiphoton tomography of patients with skin diseases
JenLab GmbH, Schillerstrasse 1, 07745 Jena, Germany
J Biophotonics 2:389-97. 2009
..47 patients with a variety of skin diseases and disorders such as skin cancer, psoriasis, hemangioma, connective tissue diseases, pigmented lesions, and ..
- Mobile teledermatology in the developing world: implications of a feasibility study on 30 Egyptian patients with common skin diseases
Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Am Acad Dermatol 64:302-9. 2011
- An IFN-associated cytotoxic cellular immune response against viral, self-, or tumor antigens is a common pathogenetic feature in "interface dermatitis"
Department of Dermatology, University of Bonn, Bonn, Germany
J Invest Dermatol 128:2392-402. 2008
- Loss of serum response factor in keratinocytes results in hyperproliferative skin disease in mice
Institute of Cell Biology, Department of Biology, ETH Zurich, Zurich, Switzerland
J Clin Invest 119:899-910. 2009
..These results reveal that loss of SRF disrupts epidermal homeostasis and strongly suggest its involvement in the pathogenesis of hyperproliferative skin diseases, including psoriasis.
- The risk of arsenic induced skin lesions in Bangladeshi men and women is affected by arsenic metabolism and the age at first exposure
Anna Lena Lindberg
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Toxicol Appl Pharmacol 230:9-16. 2008
..Thus, it can be speculated that this is due to a programming effect of arsenic in utero...
- Ozone and ozonated oils in skin diseases: a review
Dipartimento Farmaco Chimico Tecnologico, Universita degli Studi di Siena, Viale Aldo Moro 2, 53100 Siena, Italy
Mediators Inflamm 2010:610418. 2010
- Chemotherapy-induced dermatological toxicity: frequencies and impact on quality of life in women's cancers. Results of a prospective study
Department of Gynecology and Obstetrics, Charite, Campus Virchow Klinikum, University Hospital, Berlin, Germany
Support Care Cancer 16:267-73. 2008
..The study aimed to determine the prevalence of dermatological side effects and its impact on quality of life in patients receiving systemic chemotherapy for women's cancers...
- Psychosomatic assessment of skin diseases in clinical practice
Dermatological Institute IDI IRCCS, Rome, Italy
Psychother Psychosom 74:315-22. 2005
..was to provide a systematic psychosocial evaluation of a large and heterogeneous population of patients with skin diseases, including assessments of quality of life, psychiatric status according to the DSM-IV and psychological ..
- Learning more from microarrays: insights from modules and networks
David J Wong
Program in Epithelial Biology, Stanford University School of Medicine, Stanford, California 94305, USA
J Invest Dermatol 125:175-82. 2005
- Cytogenetic damage and genetic variants in the individuals susceptible to arsenic-induced cancer through drinking water
Indian Institute of Chemical Biology, Kolkata, and West Bank Hospital, Howrah, India
Int J Cancer 118:2470-8. 2006
..24-2.22). These results show a protective role of GSTM1 null in arsenic toxicity. This study also indicates that asymptomatic individuals are sub clinically affected and are also significantly susceptible to arsenic-induced genotoxicity...
- A review of 55 cases of cutaneous lymphoid hyperplasia: reassessment of the histopathologic findings leading to reclassification of 4 lesions as cutaneous marginal zone lymphoma and 19 as pseudolymphomatous folliculitis
Department of Pathology, Saitama Medical School, Iruma gun, Japan
Hum Pathol 36:505-11. 2005
..Pseudolymphomatous folliculitis was identified by the presence of activated pilosebaceous units with abundant CD1a-and S-100 protein-positive T-cell-activated dendritic cells. Of the cases that were reassessed, 34.5% were PLF...
- Merkel cell polyomavirus DNA detection in lesional and nonlesional skin from patients with Merkel cell carcinoma or other skin diseases
Laboratory of Virology, Department of Biology and Pathology, University of Montpellier I, 34295 Montpellier, France
Br J Dermatol 162:59-63. 2010
..Results MCPyV DNA was detected in 14 of 18 (78%) patients with MCC, five of 18 (28%) patients with other skin diseases (P = 0.007) and one of six (17%) clinically healthy subjects...
- Dermatologic lesions in asymptomatic blood donors seropositive for human T cell lymphotropic virus type-1
Denise Utsch Gonçalves
Department of Internal Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil
Am J Trop Med Hyg 68:562-5. 2003
..77, 95% confidence interval [CI] = 4.11-18.71). The most common skin diseases were dermatophytoses (adjusted OR = 3.32, 95% CI = 1.50-7.35), seborrheic dermatitis (OR = 3.53, 95% CI = 0...
- Topical treatment with povidone iodine reduces nitrogen mustard-induced skin collagenolytic activity
Faculty of Sciences, Berman Building, The Hebrew University, Edmond Safra Campus, Givat Ram, 91904 Jerusalem, Israel
Arch Toxicol 76:119-21. 2002
..Reduced collagenolytic activity may serve as one of the mechanisms by which iodine protects the skin against chemical insult...
- Rectal and cutaneous malakoplakia in an orthotopic cardiac transplant recipient
J C Teeters
Department of Cardiology, University of Rochester Medical Center, Rochester, New York 14609, USA
J Heart Lung Transplant 26:411-3. 2007
..We review the current perspectives on the pathophysiology, diagnosis and treatment of this disease...
- Role of soluble and cell surface molecules in the pathogenesis of autoimmune skin diseases
Di S E M Section of Dermatology, University of Genoa, Genoa, Italy
Clin Exp Rheumatol 24:S7-13. 2006
..Data regarding the activity of DNAse in patients with cutaneous lupus erythematosus as a possible risk factor for the development of systemic disease are here reported...
- The prevalence of skin diseases in the elderly: analysis of 4099 geriatric patients
Ankara Numune Education and Research Hospital, Dermatology Department, and Hacettepe University Institute of Oncology, Ankara, Turkey
Int J Dermatol 45:672-6. 2006
..The geriatric population is composed of persons over 65 years of age, and few studies are available on the dermatologic diseases in this group...
- The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology
David R Bickers
Department of Dermatology, Columbia University College of Physicians and Surgeons, New York, USA
J Am Acad Dermatol 55:490-500. 2006
..2 billion dollars. Including the economic burden on quality of life, the total economic burden of skin disease to the US public in 2004 was approximately 96 billion dollars...
- Pruritus and hydration state of stratum corneum in hemodialysis patients
First Department of Medicine, Hamamatsu University School of Medicine, Hamamatsu, Japan
Am J Nephrol 20:437-42. 2000
..Since the skin surface hygrometer can detect the changes of water content in the stratum corneum more sensitively, we re-examined the relationship between the severity of pruritus and water content in dialysis patients...
- Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseases
Department of Dermatology, Graduate School of Medicine, Faculty of Medicine, University of Tokyo, Bunkyo ku, Tokyo 113 8655, Japan
J Dermatol Sci 43:75-84. 2006
..TARC is designated a Th2 type chemokine since it binds to CCR4. We review the pathogenic role of TARC in skin diseases such as atopic dermatitis (AD), bullous pemphigoid (BP) and mycosis fungoides (MF) focusing on epidermal KC ..
- A case of persistent subepidermal calcified nodule in an adult treated with CO2 laser
Young Hyun Joo
Department of Dermatology, Seoul National University College of Medicine, Seoul, and Seoul National University Bundang Hospital, Gyeonggi, Korea
J Dermatol 31:480-3. 2004
..The treatment of choice is believed to be surgical excision. We describe a case of SCN on the right ear lobe of a 33-year-old male, which was treated using a CO2 laser and electrodessication...
- Keratinocyte apoptosis in epidermal development and disease
Huntsman Cancer Institute, University of Utah Health Sciences Center, Salt Lake City, Utah 84112, USA
J Invest Dermatol 126:243-57. 2006
..Dysfunctional apoptosis occurs in some skin diseases, such as psoriasis and skin cancer...
- Insights into the pathophysiology and management of dermatologic toxicities to EGFR-targeted therapies in colorectal cancer
Mario E Lacouture
Cancer Skin Care Program and SERIES Clinic, Department of Dermatology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Ill 60611 2941, USA
Cancer Nurs 30:S17-26. 2007
..Effective management of these adverse effects may lessen the chance of suboptimal therapy and requires an understanding of the underlying pathophysiology, as well as knowledge of useful strategies for alleviating these effects...
- In vitro antimicrobial activity of certain medicinal plants from eastern Ghats, India, used for skin diseases
A Jeevan Ram
Department of Botany, Sri Krishnadevaraya University, Anantapur 515003, India
J Ethnopharmacol 90:353-7. 2004
..Ethanolic extracts of 23 crude drug samples used for various skin diseases were assayed for antimicrobial activity against four bacterial and one fungal human pathogens.
- Recalcitrant cutaneous sarcoidosis responding to infliximab
Michael P Heffernan
Arch Dermatol 141:910-1. 2005
Michael C Iannuzzi
Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Mount Sinai School of Medicine, New York, USA
N Engl J Med 357:2153-65. 2007
- Cellular genomic maps help dissect pathology in human skin disease
Asifa S Haider
Laboratory of Investigative Dermatology, The Rockefeller University, New York, New York 10021 6399, USA
J Invest Dermatol 128:606-15. 2008
..We were able to ascribe over 90% of these genes to specific cell types, and there was a surprisingly large contribution from DCs. This shows the utility of such cellular gene maps...
- Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response
Ali R Djalilian
National Human Genome Research Institute, National Eye Institute, and National Institute of Child Health and Development, NIH, Bethesda, Maryland 20892, USA
J Clin Invest 116:1243-53. 2006
..More generally, these studies suggest that the most effective treatments for inflammatory skin disorders might concomitantly suppress the immune response and enhance epidermal differentiation to restore the barrier...
- Hyaluronic acid in the treatment and prevention of skin diseases: molecular biological, pharmaceutical and clinical aspects
Department of Dermatology and Allergology, Ludwig Maximilian University, Munich, Germany
Skin Pharmacol Physiol 17:207-13. 2004
..Increased HA concentrations have been associated with inflammatory skin diseases. In clinical trials, topical application of HA improved wound healing; in particular, acute radioepithelitis, ..
- Cutaneous side-effects in patients on long-term treatment with epidermal growth factor receptor inhibitors
Department of Dermatology, Institute Gustave Roussy, Villejuif, France
Br J Dermatol 161:515-21. 2009
..Much less is known about the chronic cutaneous effects of these drugs and about their potential psychosocial impact on patients...
- Oxidative stress in the pathogenesis of skin disease
David R Bickers
Department of Dermatology, Columbia University Medical Center, New York, New York, USA
J Invest Dermatol 126:2565-75. 2006
..Although many antioxidants have shown substantive efficacy in cell culture systems and in animal models of oxidant injury, unequivocal confirmation of their beneficial effects in human populations has proven elusive...
- Acute and chronic effects of sulfur mustard on the skin: a comprehensive review
Research Center of Chemical Injuries, Baqiyatallah University of Medical Sciences, Mollasadra St, Tehran, Iran
Cutan Ocul Toxicol 29:269-77. 2010
..The aim of this article is to review the acute and long-term cutaneous findings resulting from SM exposure. Also, cellular and molecular mechanism involved in SM-induced skin pathology have been discussed...
- Gadolinium is detectable within the tissue of patients with nephrogenic systemic fibrosis
Whitney A High
Department of Dermatology, University of Colorado Health Sciences Center, Denver, USA
J Am Acad Dermatol 56:21-6. 2007
..We sought to detect gadolinium within the skin and soft tissue of patients with NSF who were exposed to gadolinium-based contrast...
- Decorative cosmetics improve the quality of life in patients with disfiguring skin diseases
Wolf Henning Boehncke
Department of Dermatology, Johann Wolfgang Goethe University, Theodor Stern Kai 7, D 60590, Frankfurt Main, Germany
Eur J Dermatol 12:577-80. 2002
..Twenty female patients (16-69 y) with skin diseases affecting the patients' face (acne, n = 8; rosacea, n = 9; chronic discoid lupus erythematodes, n = 2; ..
- Innovative use of topical calcineurin inhibitors
Andrew N Lin
Division of Dermatology and Cutaneous Sciences, University of Alberta, 2 104 Clinical Sciences Building, Edmonton, Alberta, T6G 2G3, Canada
Dermatol Clin 28:535-45. 2010
..Topical calcineurin inhibitors have been effective in many other cutaneous disorders, and further studies would help clarify their roles...
- Chemokine networks in inflammatory skin diseases
Istituto Dermopatico dell Immacolata, IRCCS, Via Monti di Creta 104, 00167 Roma, Italy
Eur J Dermatol 14:203-8. 2004
..and promiscuous, and forms a complex network relevantly involved in the expression of chronic inflammatory skin diseases, including allergic contact dermatitis, atopic dermatitis and psoriasis...
- AGE-modified collagens I and III induce keratinocyte terminal differentiation through AGE receptor CD36: epidermal-dermal interaction in acquired perforating dermatosis
Department of Dermatology, National Defense Medical College, Tokorozawa, Saitama, Japan
J Invest Dermatol 130:405-14. 2010
- Arsenic metabolism, genetic susceptibility, and risk of premalignant skin lesions in Bangladesh
Departments of Epidemiology, Columbia University, USA
Cancer Epidemiol Biomarkers Prev 16:1270-8. 2007
- EKV mutant connexin 31 associated cell death is mediated by ER stress
Centre for Cutaneous Research, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK
Hum Mol Genet 18:4734-45. 2009
..These results indicate that, in vivo, ER stress may lead to abnormal keratinocyte differentiation and hyperproliferation in EKV patient skin...
- Cutaneous side effects of epidermal growth factor receptor inhibitors: clinical presentation, pathogenesis, and management
Jenny C Hu
David Geffen School of Medicine at University of California, Los Angeles 90095, USA
J Am Acad Dermatol 56:317-26. 2007
..With effective management of these side effects, dermatologists can play an integral role in facilitating compliance with anti-EGFR therapy and aid with effective oncologic management...
- Efficacy and skin toxicity management with cetuximab in metastatic colorectal cancer: outcomes from an oncologic/dermatologic cooperation
Centro Universitario di Ricerca Oncologica, Oncologia Medica I, ASO San Giovanni Battista Ospedale Molinette, Torino, Italy
Clin Colorectal Cancer 7:48-54. 2008
..The aim of this study was to investigate the efficacy of the combination of irinotecan/cetuximab and to plan related skin toxicity management with an oncologic/dermatologic team...
- The mystery of Morgellons disease: infection or delusion?
Virginia R Savely
South Austin Family Practice Clinic, Austin, Texas, USA
Am J Clin Dermatol 7:1-5. 2006
..Further clinical and molecular research is needed to unlock the mystery of Morgellons disease...
- Cutaneous manifestations of internal malignancy
Bruce H Thiers
Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, SC, USA
CA Cancer J Clin 59:73-98. 2009
- Chronic health effects in people exposed to arsenic via the drinking water: dose-response relationships in review
Department of Health Science, Asahikawa Medical College, Asahikawa, Hokkaido 078 8510, Japan
Toxicol Appl Pharmacol 198:243-52. 2004
- Nephrogenic fibrosing dermopathy with systemic involvement
William W Ting
Department of Dermatology, University of Iowa College of Medicine, Iowa City, USA
Arch Dermatol 139:903-6. 2003
..Soft tissue calcification is rare in patients with NFD and systemic involvement has not been reported...
- Immunopathogenesis of sarcoidosis
Division of Pulmonary and Critical Care Medicine, Indiana University and the Richard L Roudebush VA Medical Center, Indianapolis, IN
Clin Dermatol 25:250-8. 2007
- Lipid nanoparticles for improved topical application of drugs for skin diseases
Institut fur Pharmazie, Pharmakologie und Toxikologie, der Freien Universität Berlin, D 14195 Berlin, Germany
Adv Drug Deliv Rev 59:427-43. 2007
..A special focus is upon the interactions of active ingredients and the lipid matrix as well as the quantification of dermal penetration...
- Dialysis-associated systemic fibrosis (nephrogenic fibrosing dermopathy): study of inflammatory cells and transforming growth factor beta1 expression in affected skin
Sergio A Jimenez
Division of Rheumatology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107 5541, USA
Arthritis Rheum 50:2660-6. 2004
..The aim of the present study was to describe the clinical and histopathologic features of 9 new cases and to characterize the inflammatory cells and expression of transforming growth factor beta1 (TGFbeta1) in affected skin...
- Prevalence of skin diseases at a healthcare clinic in a small Brazilian town
Tatiana Federige Oliveira
Asas de Socorro, Belem, PA, Brazil
An Bras Dermatol 85:947-9. 2010
Doctors who are not specialists in dermatology often have difficulty diagnosing and managing prevalent skin diseases. The objective of this study was to evaluate the prevalence of skin diseases during a three-day healthcare clinic ..
- The effects of alcohol and drug abuse on the skin
Stephanie W Liu
Department of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, 12901 Bruce B Downs Blvd, MDC 79, Tampa, FL 33612, USA
Clin Dermatol 28:391-9. 2010
- Long-term skin damage due to chemical weapon exposure
Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran
Cutan Ocul Toxicol 30:64-8. 2011
..Skin xerosis and pruritus, pigmentation disorders, scars, and cherry angiomas are among the most common long-term skin lesions after contact with SM. Although SM is a well-known carcinogenic substance, skin cancers are rarely reported...
- Clinical role and application of superficial chemical peels in today's practice
Diane S Berson
New York Presbyterian Hospital, New York, NY, USA
J Drugs Dermatol 8:803-11. 2009
..Used properly, the superficial chemical peel has the potential to fill an important therapeutic need in the treatment armamentarium of dermatologists and plastic surgeons...
- Cutaneous amyloidosis: a concept review
Department of Pathology, Hospital El Bierzo, Ponferrada, Spain
Am J Dermatopathol 34:1-14; quiz 15-7. 2012
..We present a review, from Virchow to present, of the concepts related to amyloidosis: its nature, the classification of cutaneous forms of the disease, and the techniques used in its diagnosis...