myxoma

Summary

Summary: A benign neoplasm derived from connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix, thereby resembling primitive mesenchymal tissue. It occurs frequently intramuscularly where it may be mistaken for a sarcoma. It appears also in the jaws and the skin. (From Stedman, 25th ed)

Articles from Journal RESEARCH

Top Publications

  1. ncbi A large left atrial myxoma
    Jagdish Butany
    Department of Pathology, Toronto General Hospital, Toronto, Canada
    J Card Surg 19:547-51. 2004
  2. ncbi The challenge presented by right atrial myxoma
    Eberhard Kuon
    Department of Cardiology, Klinik Fraenkische Schweiz, Ebermannstadt, Germany
    Herz 29:702-9. 2004
  3. pmc Massive right atrial myxoma presenting as syncope and exertional dyspnea: case report
    Olga Azevedo
    Cardiology Department, Centro Hospitalar do Alto Ave Unidade de Guimarães, Guimaraes, Portugal
    Cardiovasc Ultrasound 8:23. 2010
  4. ncbi A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata
    Steffen Rickelt
    Helmholtz Group for Cell Biology, German Cancer Research Center, Heidelberg, Germany
    Mod Pathol 23:1429-37. 2010
  5. ncbi Cardiac myxoma: its origin and tumor characteristics
    Jun Amano
    Department of Surgery, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Ann Thorac Cardiovasc Surg 9:215-21. 2003
  6. pmc Cardiac tumours in children
    Orhan Uzun
    Department of Paediatric Cardiology, University Hospital of Wales, Heath Park Cardiff, CF14 4XW, Wales, UK
    Orphanet J Rare Dis 2:11. 2007
  7. ncbi Multiple myxomas originating from anterior and posterior mitral leaflets in the left ventricle leading to LV outflow tract obstruction
    Ali Vefa Ozcan
    Department of Cardiovascular Surgery, Pamukkale University, Denizli, Turkey
    Circ J 72:1709-11. 2008
  8. ncbi Sex distribution in cardiac myxomas
    Dong Hi Anthony Yoon
    Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246, USA
    Am J Cardiol 90:563-5. 2002
  9. ncbi Benign cardiac tumors and tumorlike conditions
    Deepali Jain
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Diagn Pathol 14:215-30. 2010
  10. ncbi Cardiac myxoma the great imitators: comprehensive histopathological and molecular approach
    Igor Gosev
    Department of Cardiac Surgery University Hospital Centre Zagreb, Croatia Kišpatićeva 12, 10 000 Zagreb, Croatia
    Int J Cardiol 164:7-20. 2013

Detail Information

Articles from Journal RESEARCH1

Publications309 found, 100 shown here

  1. ncbi A large left atrial myxoma
    Jagdish Butany
    Department of Pathology, Toronto General Hospital, Toronto, Canada
    J Card Surg 19:547-51. 2004
  2. ncbi The challenge presented by right atrial myxoma
    Eberhard Kuon
    Department of Cardiology, Klinik Fraenkische Schweiz, Ebermannstadt, Germany
    Herz 29:702-9. 2004
    Right atrial myxoma can be heralded by nonspecific constitutional symptoms-i. e., remittent or lasting fever; weight loss; chronic anemia and general arthralgia-and may escape timely diagnosis until severe complications develop: i. e...
  3. pmc Massive right atrial myxoma presenting as syncope and exertional dyspnea: case report
    Olga Azevedo
    Cardiology Department, Centro Hospitalar do Alto Ave Unidade de Guimarães, Guimaraes, Portugal
    Cardiovasc Ultrasound 8:23. 2010
    Primary heart neoplasms are rare occurring with an estimated incidence of 0.0017-0.19%. Myxoma is the most prevalent primary heart tumor. The right atrium is an unusual localization, occurring only in 15-20% of myxoma cases...
  4. ncbi A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata
    Steffen Rickelt
    Helmholtz Group for Cell Biology, German Cancer Research Center, Heidelberg, Germany
    Mod Pathol 23:1429-37. 2010
    ..We propose to examine the marker value of Pkp2 in clinical diagnoses of cardiac myxomata and to develop Pkp2-targeted therapeutic reagents...
  5. ncbi Cardiac myxoma: its origin and tumor characteristics
    Jun Amano
    Department of Surgery, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Ann Thorac Cardiovasc Surg 9:215-21. 2003
    Cardiac myxoma is most common among primary cardiac tumors, and its origin and tumor characteristics have been gradually elucidated by recent advances in molecular biology...
  6. pmc Cardiac tumours in children
    Orhan Uzun
    Department of Paediatric Cardiology, University Hospital of Wales, Heath Park Cardiff, CF14 4XW, Wales, UK
    Orphanet J Rare Dis 2:11. 2007
    ..Surgery, chemotherapy and radiotherapy may prolong survival. The prognosis for malignant primary cardiac tumours is generally extremely poor...
  7. ncbi Multiple myxomas originating from anterior and posterior mitral leaflets in the left ventricle leading to LV outflow tract obstruction
    Ali Vefa Ozcan
    Department of Cardiovascular Surgery, Pamukkale University, Denizli, Turkey
    Circ J 72:1709-11. 2008
    ..The myxomas were successfully removed with the mitral leaflets via left atriotomy and mitral valve replacement. No embolic events occurred in the preoperative or postoperative period. In this article, we wanted to present...
  8. ncbi Sex distribution in cardiac myxomas
    Dong Hi Anthony Yoon
    Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246, USA
    Am J Cardiol 90:563-5. 2002
  9. ncbi Benign cardiac tumors and tumorlike conditions
    Deepali Jain
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Diagn Pathol 14:215-30. 2010
    ..This comprehensive and up-to-date review describes the key clinical, gross, and histologic findings for 16 distinct entities. It also provides differential diagnoses and key facts to differentiate between similar appearing tumors...
  10. ncbi Cardiac myxoma the great imitators: comprehensive histopathological and molecular approach
    Igor Gosev
    Department of Cardiac Surgery University Hospital Centre Zagreb, Croatia Kišpatićeva 12, 10 000 Zagreb, Croatia
    Int J Cardiol 164:7-20. 2013
    ..Majority of cardiac myxoma occur sporadically while a relatively small proportion of diagnosed cases develop as a part of Carney complex ..
  11. ncbi Surgical excision of cardiac myxomas: twenty years experience at a single institution
    Andrea Garatti
    Division of Cardiac Surgery and First Vascular Surgery Unit, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Donato Hospital, San Donato Milanese, and Faculty of Medicine, University of Milan, Milan, Italy
    Ann Thorac Surg 93:825-31. 2012
    ..Primary cardiac tumors are quite uncommon and myxomas constitute the major proportion among these masses. The present study summarizes our 20-year clinical experience with surgical resection of intracardiac myxomas...
  12. ncbi Mandibular reconstruction using fresh frozen bone allograft after conservative enucleation of a mandibular odontogenic myxoma
    Massimo Albanese
    Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy
    J Craniofac Surg 23:831-5. 2012
    ..radiographic, and histological findings about a case of a young woman affected by a mandibular odontogenic myxoma. Conservative tumor resection was followed by immediate reconstructive treatment using fresh-frozen human bone ..
  13. ncbi A rare case of conjunctival myxoma and a review of the literature
    Ching Long Chen
    Department of Ophthalmology, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC
    Ophthalmologica 222:136-9. 2008
    ..To report on an 11-year-old boy with a painless slow-growing temporal bulbar conjunctival mass of his left eye...
  14. ncbi Odontogenic myxoma of the maxilla: a report of two pediatric cases
    Bryan G Wachter
    Department of Otolaryngology Head and Neck Surgery, Loyola University Medical Center, 2160 S First Avenue, Maywood, IL 60153 5590, USA
    Int J Pediatr Otorhinolaryngol 67:389-93. 2003
    ..Nevertheless, myxoma is a very uncommon lesion of the midface, particularly in the pediatric population...
  15. ncbi Report of a conjunctival myxoma case and review of the literature
    Hakan Demirci
    Oncology Service, Wills Eye Hospital, 840 Walnut Street, Philadelphia, PA 19107, USA
    Arch Ophthalmol 124:735-8. 2006
  16. ncbi Aggressive angiomyxoma: a second case of metastasis with patient's death
    Stella Blandamura
    Department of Oncological and Surgical Sciences, University of Padua, Italy
    Hum Pathol 34:1072-4. 2003
    ..We document this case and report a similar one, found in the literature, of a postmenopausal woman with pulmonary and mediastinic metastases. These cases may expand the current concepts of potential behavior of aggressive angiomyxoma...
  17. ncbi Cardiac myxoma: a 13-year experience in echocardiographic diagnosis
    Ricardo Oliveira
    Servico de Cardiologia, Hospital de Santa Marta, Lisboa, Portugal
    Rev Port Cardiol 29:1087-100. 2010
    ..The authors review their thirteen years' experience on the echocardiographic diagnosis of this pathology...
  18. pmc Biatrial myxoma and cerebral ischemia successfully treated with intravenous thrombolytic therapy and surgical resection
    Morhaf Ibrahim
    Department of Internal Medicine, Division of Cardiology, and Department of Neurology at the University of Texas Health Science Center Medical School at Houston, Houston, Texas 77030, USA
    Tex Heart Inst J 35:193-5. 2008
    ..agent was used successfully--without massive intracranial bleeding--to treat acute stroke induced by atrial myxoma. Our patient, who had biatrial myxomas with a dual blood supply from the right coronary artery, presented with ..
  19. ncbi Cardiac myxomas: 24 years of experience in 49 patients
    I M Keeling
    Department of Surgery, Division of Cardiac Surgery, Karl Franzens University Graz, Graz, Austria
    Eur J Cardiothorac Surg 22:971-7. 2002
    In this single-center study we reviewed our experience with a significant number of cardiac myxoma cases occurring over the past two decades.
  20. ncbi Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis
    Zhirong Yin
    Department of Molecular Virology, Immunology, and Molecular Genetics, Ohio State University, Columbus, USA
    Circulation 117:1414-22. 2008
    ..Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype...
  21. ncbi Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex
    L S Kirschner
    Unit on Genetics and Endocrinology, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, Maryland, USA
    Nat Genet 26:89-92. 2000
    ..We conclude that germline mutations in PRKAR1A, an apparent tumour-suppressor gene, are responsible for the CNC phenotype in a subset of patients with this disease...
  22. ncbi Carney complex: pathology and molecular genetics
    Sosipatros A Boikos
    Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA
    Neuroendocrinology 83:189-99. 2006
    ..CNC is the first human disease caused by mutations of one of the subunits of the PKA holoenzyme, a critical component of numerous cellular signaling systems. This has wide implications for cAMP involvement in endocrine tumorigenesis...
  23. ncbi Clinical presentation of left atrial cardiac myxoma. A series of 112 consecutive cases
    L Pinede
    Department of Internal Medicine, Edouard Herriot Hospital, 69437 Lyons, France
    Medicine (Baltimore) 80:159-72. 2001
    We analyzed a series of 112 consecutive cases of left atrial myxoma diagnosed in a single French hospital (72 women and 40 men; age range, 5-84 yr) over 40 years, from 1959 to 1998...
  24. pmc Carney complex (CNC)
    Jerome Bertherat
    Centre de Référence Maladies Rares de la Surrénale, Service d endocrinologie, Hopital Cochin, INSERM U 567, CNRS UMR 8104, Institut Cochin, Universite Rene Descartes Paris 5, Paris, 75014, France
    Orphanet J Rare Dis 1:21. 2006
    ..Bilateral adrenalectomy is the most common treatment for Cushing's syndrome due to PPNAD...
  25. ncbi Safe and effective intravenous thrombolysis for acute ischemic stroke caused by left atrial myxoma
    Christian D Nagy
    Division of Cardiology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Stroke Cerebrovasc Dis 18:398-402. 2009
    Atrial myxoma may be associated with syncope or sudden death attributed to left-sided cardiac outflow obstruction or embolization caused by tumor dislodgement or thrombus formation...
  26. ncbi A huge obstructive myxoma located in the right heart without causing any symptom
    Murat Yuce
    Int J Cardiol 114:405-6. 2007
    Cardiac myxoma is unusual and mostly located in left atrium...
  27. ncbi Significance of monocyte chemotactic protein-1 and thymidine phosphorylase in angiogenesis of human cardiac myxoma
    Tianshu Zhang
    Second Department of Surgery, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
    Circ J 67:54-60. 2003
    ..and of thymidine phosphorylase (TP) correlates with the angiogenesis and clinicopathologic features in cardiac myxoma. Paraffin-embedded specimens of 17 resected cardiac myxomas were immunohistochemically stained for MCP-1, CC ..
  28. ncbi Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases
    Kun Yu
    Division of Cardiothoracic Surgery, Extracorporeal Circulation and Anatomic Pathology, Cardiovascular Institute and Fuwai Hospital, CAMS and PUMS, Beijing 100037, China
    Interact Cardiovasc Thorac Surg 6:636-9. 2007
    ..6% vs. 9.4%, P<0.01). The most common benign cardiac tumor was myxoma (86.8%). Mesenchymoma and angiosarcoma were the most common primary malignant cardiac tumors...
  29. ncbi The variations in the immunologic features and interleukin-6 levels for the surgical treatment of cardiac myxomas
    Hiroki Yokomuro
    Department of Surgery, Division of Cardiovascular Surgery, Toho University School of Medicine, 6 11 1 Omori Nishi, Tokyo 143 8541, Japan
    Surg Today 37:750-3. 2007
    In this study, we propose the existence of a relationship between cardiac myxomas and the immunologic features or interleukin-6 (IL-6), while also considering the optimal treatment of cardiac myxoma, especially "familial myxoma."
  30. pmc Unusual presentation of localized gingival enlargement associated with a slow-growing odontogenic myxoma
    Jaume Miranda Rius
    Departament d Odontostomatologia, Facultat d Odontologia, Universitat de Barcelona, Barcelona, Spain
    Int J Oral Sci 5:172-5. 2013
    ..Tissue submitted for histopathological analysis rendered the diagnosis of odontogenic myxoma. After 12-month of follow-up, no evidence of recurrence was found...
  31. pmc Cardiomyogenic differentiation in cardiac myxoma expressing lineage-specific transcription factors
    Hiroaki Kodama
    Cardiovascular Center, Saiseikai Central Hospital, Tokyo, Japan
    Am J Pathol 161:381-9. 2002
    We investigated five cases of cardiac myxoma and one case of cardiac undifferentiated sarcoma by light and electron microscopy, in situ hybridization, immunohistochemical staining, and reverse transcriptase-polymerase chain reaction for ..
  32. ncbi Giant left atrial myxoma: an unusual cause of acute pulmonary edema
    Rodolfo Citro
    U O UTIC Cardiologia, San Luca Hospital, Vallo della Lucania, Italy
    J Am Soc Echocardiogr 21:978.e1-3. 2008
    We report a case of a huge left atrial myxoma with an unusual clinical presentation characterized by acute pulmonary edema. The possible pathophysiologic mechanism has been discussed.
  33. ncbi Myxoma in the right ventricular outlow tract
    Maria Isabel Sá
    Serviço de Cirurgia Cardio Torácica dos Hospitais da Universidade de Coimbra, Coimbra, Portugal
    Rev Port Cardiol 26:377-81. 2007
    ..cyanosis and presyncope during exercise related to intermittent obstruction of the right outflow tract by a myxoma of the right ventricle attached to the membranous interventricular septum by its pedicle...
  34. ncbi Central nervous system manifestations of cardiac myxoma
    Vivien H Lee
    Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Arch Neurol 64:1115-20. 2007
    Neurologic complications can be the initial manifestation of atrial myxoma. Prompt diagnosis is of paramount significance to prevent recurrent complications.
  35. ncbi Expression of basic fibroblast growth factor and its receptor-1 in cardiac myxoma
    H Fujisawa
    Second Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan
    J Cardiovasc Surg (Torino) 43:589-94. 2002
    To clarify the significance of basic fibroblast growth factor (bFGF) in angiogenesis or proliferative activity in cardiac myxoma, the expression of bFGF and its receptor (FGFR-1) were immunohistochemically examined.
  36. ncbi Radiographic examination of 41 cases of odontogenic myxomas on the basis of conventional radiographs
    J Zhang
    Department of Oral Radiology, West China College of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, China
    Dentomaxillofac Radiol 36:160-7. 2007
    There are some different radiographic appearances of odontogenic myxoma that have not been reported in the published literature...
  37. ncbi Giant cardiac myxoma
    Peter Barlis
    Department of Cardiology, Austin Hospital, P O Box 5555, Heidelberg, VIC 3084, Australia
    Heart Lung Circ 16:389-91. 2007
    ..pain and discuss a number of diagnostic challenges that were confronted up until a definitive diagnosis of cardiac myxoma was made...
  38. ncbi Leiomyosarcoma of the left atrium mimicking a left atrial myxoma
    Alessandro Mazzola
    Department of Cardiac Surgery, G Mazzini Hospital, Teramo, Italy
    J Thorac Cardiovasc Surg 131:224-6. 2006
  39. ncbi Inherited disposition to cardiac myxoma development
    David Wilkes
    Greenberg Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, 525 East 68th Street, New York, New York 10021, USA
    Nat Rev Cancer 6:157-65. 2006
    ..Ongoing investigations are exploring the intersection of R1alpha-dependent cell signalling with other gene products such as perinatal myosin, mutation of which can also cause cardiac myxomas...
  40. ncbi Multiple cardiac myxomas with pulmonary arterial obstruction and acute right heart failure
    Koichi Sughimoto
    Department of Cardiovascular Surgery, Cardiovascular Center of Sendai, 21 1 Honda chou, Izumi ku, Sendai 981 3107, Japan
    Jpn J Thorac Cardiovasc Surg 52:530-3. 2004
    ..Following the removal of the tumor, symptoms improved drastically. The postoperative course was uneventful...
  41. ncbi Cardiac myxoma cells exhibit embryonic endocardial stem cell features
    A Orlandi
    Institute of Anatomic Pathology, Tor Vergata University of Rome, Italy
    J Pathol 209:231-9. 2006
    The origin of myxoma, the most frequent tumour of the heart, remains uncertain...
  42. ncbi Production of endothelin-1 and big endothelin-1 by human cardiac myxoma cells--implications of the origin of myxomas--
    Hironosuke Sakamoto
    Department of General Practice Medicine, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Circ J 68:1230-2. 2004
    ..Although the origin of cardiac myxomas is still controversial, the 2 main hypotheses are that the tumor cells originate either from multipotential mesenchymal cells or from endocardial neural tissue...
  43. ncbi Nerve sheath myxoma: a clinicopathologic and immunohistochemical analysis of 57 morphologically distinctive, S-100 protein- and GFAP-positive, myxoid peripheral nerve sheath tumors with a predilection for the extremities and a high local recurrence rate
    John F Fetsch
    Department of Soft Tissue Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Am J Surg Pathol 29:1615-24. 2005
    This report describes the clinicopathologic findings in 57 cases of nerve sheath myxoma. Our study group included 34 males and 23 females, ranging from 8 to 72 years of age at the time of their first surgical procedure (mean, 36 years; ..
  44. pmc Atypical vessels as an early sign of intracardiac myxoma?
    Hans Peter Dübel
    Medical Clinic for Cardiology, Angiology, Pulmology, Charite Campus Mitte, University Medicine Berlin, Germany
    Cardiovasc Ultrasound 2:13. 2004
    We report on a woman with previously unknown left atrial myxoma, who underwent percutaneous coronary intervention...
  45. ncbi Mutation of perinatal myosin heavy chain associated with a Carney complex variant
    Mark Veugelers
    Molecular Cardiology Laboratory, Greenberg Cardiology Division, Department of Medicine, Weill Medical College of Cornell University, New York 10021, USA
    N Engl J Med 351:460-9. 2004
    ..To identify the cause of a Carney complex variant associated with distal arthrogryposis (the trismus-pseudocamptodactyly syndrome), we performed clinical and genetic studies...
  46. ncbi Left atrial myxoma presenting as acute inferior wall infarction--a case report
    J Butany
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada
    J Card Surg 21:479-80. 2006
  47. ncbi Primary corneal myxoma
    Louise Hillerup Hansen
    Department of Ophthalmology, Arhus University Hospital, Arhus, Denmark
    Acta Ophthalmol Scand 82:224-7. 2004
    To present the clinical and histopathological characteristics of a corneal myxoma.
  48. ncbi Odontogenic myxoma of the mandible: a case report
    Rohit Sharma
    Department of Pathology, Pt B D Sharma PGIMS, Rohtak
    Indian J Pathol Microbiol 46:84-6. 2003
    A case of myxoma of mandible in a 23 years old female patient is described. The case was treated with enbloc resection and bone graft from iliac crest. No recurrence is reported after 4 years follow up.
  49. ncbi Vulvar soft tissue tumors
    K A Behranwala
    Sarcoma and Gynecology Unit, Royal Marsden NHS Trust, London, UK
    Int J Gynecol Cancer 14:94-9. 2004
    ..To report our incidence of soft tissue tumors at this site and to discuss various prognostic factors...
  50. ncbi Myxoma of the oral soft tissues: Report of a case and literature review
    Apostolos Epivatianos
    Department of Oral Medicine and Oral Pathology, School of Dentistry, University of Thessaloniki, Greece
    J Oral Maxillofac Surg 65:317-20. 2007
  51. ncbi Odontogenic myxoma: a clinicopathologic study of 25 cases
    Tie Jun Li
    Department of Oral Pathology, School and Hospital of Stomatology, Peking University, 22 S Zhongguancun Ave, Haidian District, Beijing, PR China 100081
    Arch Pathol Lab Med 130:1799-806. 2006
    Odontogenic myxoma is an uncommon tumor that has the potential for extensive destruction of the jaws.
  52. ncbi Myxoid tissue fragments in femoral embolectomy material: cardiac myxoma versus myxoid thrombus--a diagnostic dilemma
    Riza Dogan
    Department of Cardiovascular Surgery, Medical Faculty, Hacettepe University, Ankara, Turkey
    Anadolu Kardiyol Derg 7:105-6. 2007
  53. ncbi Oral focal mucinosis: report of 15 cases and review of the literature
    Michael J Aldred
    Dorevitch Pathology, Heidelberg, Victoria, Australia
    Pathology 35:393-6. 2003
    ..To describe 15 cases of oral focal mucinosis (OFM) and compare these to previously reported cases...
  54. ncbi Soft tissue myxoma: report of an unusual case located on the gingiva
    Vittoria Perrotti
    Dental School, University of Chieti Pescara, Italy
    J Clin Periodontol 33:76-8. 2006
    Soft tissue myxoma of the oral cavity is rare. Only three cases of myxoma of gingiva have been reported in the literature...
  55. ncbi Left atrial myxoma on FDG-PET/CT
    Olivier Gheysens
    From the Departments of Nuclear Medicine, Rheumatology, Cardiology, and Radiology, University Hospital Leuven, Leuven, Belgium
    Clin Nucl Med 38:e421-2. 2013
    ..echocardiography and contrast-enhanced MRI showed a left atrial pedunculated soft tissue mass suggestive for myxoma, with histological confirmation...
  56. ncbi Imaging diagnosis-synovial myxoma of lumbar vertebrae articular process joint
    Waka H Blair
    Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, TX 77843, USA
    Vet Radiol Ultrasound 52:309-12. 2011
    Magnetic resonance (MR) imaging and histopathology were used to diagnose an articular process synovial myxoma in a dog...
  57. ncbi Eleven years' experience with Korean cardiac myxoma patients: focus on embolic complications
    Seung Jae Lee
    Department of Neurology, Sejong General Hospital, Bucheon, Republic of Korea
    Cerebrovasc Dis 33:471-9. 2012
    ..This study is based on our clinical experience with cardiac myxomas over a period of 11 years at Sejong General Hospital. We focused on the embolic complications of patients with cardiac myxoma.
  58. ncbi Superficial acral fibromyxoma: a clinicopathological study of new 41 cases from the U.K.: should myxoma (NOS) and fibroma (NOS) continue as part of 21st-century reporting?
    R J Prescott
    Department of Pathology, Blackburn Royal Infirmary, Blackburn, UK
    Br J Dermatol 159:1315-21. 2008
    ..Superficial acral fibromyxoma (SAF) remains poorly recognized by general pathologists and dermatopathologists, partly attributable to its relatively uncommon occurrence and recent documentation...
  59. ncbi Fatal cerebral embolism in a young patient with an occult left atrial myxoma
    H P Bienfait
    Department of Neurology, Medisch Centrum Haaglanden, locatie Westeinde Ziekenhuis, Lijnbaan 32, 2512 VA, The Hague, The Netherlands
    Clin Neurol Neurosurg 103:37-8. 2001
    We report a young patient with a fatal cerebral embolism from an occult atrial myxoma. The patient died before echocardiography was performed and at autopsy the definite diagnosis was made...
  60. ncbi Emergency presentation of emboli to multiple sites from an atrial myxoma
    Gordon Michael Nicholls
    Emergency Department, Auckland City Hospital, Auckland, New Zealand
    Emerg Med Australas 24:336-8. 2012
    ..and fasciotomy could not save his left lower limb, and emergency cardiac surgery was required to excise an atrial myxoma. A brief narrative review of the literature is also presented, with this case being unusual in causing such ..
  61. ncbi Using the condylar prosthesis after resection of a large odontogenic myxoma tumor in the mandible
    Willian Morais de Melo
    Surgery and Integrated Clinic Department, UNESP, Araçatuba Dental School, Sao Paulo State University, Aracatuba, Sao Paulo, Brazil
    J Craniofac Surg 23:e398-400. 2012
    ..The authors report a case of a 20-year-old patient with an odontogenic myxoma tumor located in the left mandibular angle, ascending ramus, and mandibular symphysis...
  62. ncbi Pelvic excision of large aggressive angiomyxoma in a woman: irradiation for recurrent disease
    M Suleiman
    Department of Radiooncology, Hospital of Sion, Sion, Switzerland
    Int J Gynecol Cancer 16:356-60. 2006
    ..This is, to our knowledge, the second description of a therapeutic irradiation of a recurrent AAM. Radiation therapy is able to control a recurrent AAM for at least 3 years...
  63. ncbi Unidentified retained inferior vena cava myxoma detected by intra-operative trans-oesophageal echocardiography
    H A Vohra
    Wessex Cardiothoracic Centre, Southampton, UK
    Thorac Cardiovasc Surg 58:248-50. 2010
    We report a unilateral right atrial familial myxoma with a multicentric nature discovered during cardiac surgery...
  64. pmc Carney complex, a familial multiple neoplasia and lentiginosis syndrome. Analysis of 11 kindreds and linkage to the short arm of chromosome 2
    C A Stratakis
    Section on Pediatric Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health NIH, Bethesda, Maryland 20892, USA
    J Clin Invest 97:699-705. 1996
    ..This region has exhibited cytogenetic aberrations in atrial myxomas associated with the complex, and has been characterized by microsatellite instability in human neoplasias...
  65. ncbi The role of tumor vascularisation in benign and malignant cardiovascular neoplasms: a comparison of cardiac myxoma and sarcomas of the pulmonary artery
    Andreas Gaumann
    Institut fur Pathologie, Klinikum der Universitat Regensburg, D 93053 Regensburg, Germany
    Oncol Rep 20:309-18. 2008
    ..Hypoxia appears to be the strongest inducer of neoangiogenesis in the sarcomas. The expression of receptor tyrosine kinases of the VEGF family provides a basis for an adjuvant therapy...
  66. ncbi The Fas-mediated apoptotic pathway in cardiac myxoma
    Cheng Chung Liu
    Chang Gung University, Taipei, Taiwan
    Int J Surg Pathol 18:493-8. 2010
    Cardiac myxoma is the most common primary tumor of the heart. The existence of apoptosis in cardiac myxoma has been demonstrated...
  67. ncbi Genetic alterations of Carney complex are not present in sporadic cardiac myxomas
    Franz Fogt
    Presbyterian Medical Center, University of Pennsylvania, Philadelphia, PA 19104, USA
    Int J Mol Med 9:59-60. 2002
    ..We conclude that sporadic cardiac myxomas are genetically not related to Carney complex and most likely do not represent an incomplete form of Carney complex...
  68. ncbi Mitral valve recurrence of a left atrial myxoma
    Navid Sadeghi
    Department of Cardiac Surgery, Dr Shariati Hospital, Tehran University of Medical Sciences TUMS, Tehran, Iran
    Eur J Cardiothorac Surg 21:568-73. 2002
    Recurrence of intracardiac myxoma is unusual, and heart valves are extremely rare locations for this tumor to originate, either as the primary site or the site of recurrence...
  69. ncbi Novel strategies for recurrent cardiac myxoma
    Kaushalendra Singh Rathore
    Department of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, Southern Australia, Australia
    Ann Thorac Surg 85:2125-6. 2008
    ..He had a complete neurologic recovery, but presented 2 years later with recurrence of a cardiac myxoma in his left ventricle and left atrium. This time, however, endoscopically assisted techniques were used...
  70. ncbi Proliferating cell nuclear antigen expression grossly over-estimates cellular proliferation in cardiac myxomas
    D E Roskell
    University of Oxford Nuffield, Dept of Pathology and Bacteriology, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Eur J Med Res 4:105-6. 1999
    ..Routine microscopy suggests a low proliferation rate. The aim of this study was to investigate cellular proliferation, and to assess its contribution to tumour growth...
  71. ncbi Angiomyxolipoma (vascular myxolipoma) of subcutaneous tissue
    Juan C Tardio
    Department of Pathology, Hospital El Escorial, Madrid, Spain
    Am J Dermatopathol 26:222-4. 2004
    ..This lesion requires differential diagnosis with other benign fat tissue tumors, especially myxoid spindle cell lipoma, superficial angiomyxoma, myxoid liposarcoma, and low-grade myxofibrosarcoma...
  72. ncbi Aggressive angiomyxoma mimicking inguinal hernia in a man
    Tomonori Minagawa
    Department of Urology, Azumino Red Cross Hospital, 5685 Toyoshina, Azumino, Nagano, Japan
    Int J Clin Oncol 14:365-8. 2009
    ..The findings from previously reported cases and our case suggest that AAM should be considered in patients with an inguinal or scrotal swelling with a suspicious soft tissue tumor...
  73. ncbi F-18 fluorodeoxyglucose positron emission tomography/computed tomography imaging in left thigh intramuscular myxoma
    Linh Ho
    PET Imaging Science Center, Division of Nuclear Medicine, Department of Radiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Clin Nucl Med 34:224-5. 2009
    We report F-18 FDG PET-CT appearance of biopsy-proven intramuscular myxoma (IM) in a 69-year-old woman who presented with a left thigh mass...
  74. ncbi Surrounding muscle edema detected by MRI is valuable for diagnosis of intramuscular myxoma
    Kazuto Nishimoto
    Department of Orthopaedic Surgery, Yamada Red Cross Hospital, Mie, Japan
    Oncol Rep 11:143-8. 2004
    We recently experienced 4 cases of intramuscular myxoma and analyzed MRI findings, comparing them with histological ones...
  75. pmc A case of odontogenic myxoma with unusual histological features mimicking a fibro-osseous process
    Yi Ling Lin
    Department of Diagnostic and Surgical Sciences, University of California at Los Angeles, School of Dentistry, Los Angeles, CA 90095, USA
    Head Neck Pathol 4:253-6. 2010
    Odontogenic myxoma is a rare benign but locally aggressive odontogenic tumor...
  76. ncbi Giant myxoma causing right ventricular outflow tract obstruction
    Flora H F Tsang
    Division of Cardiothoracic Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Hong Kong Med J 17:242-4. 2011
    Atrial cardiac myxoma is the most common benign cardiac tumour. Atrial myxoma most commonly arises from the left atrium and, less frequently, from the right atrium or both ventricles...
  77. ncbi Management of cardiac myxoma during pregnancy: a case series and review of the literature
    Anitha S John
    Division of Cardiology, Children s National Medical Center, George Washington University, Washington, DC 20010, United States
    Int J Cardiol 155:177-80. 2012
    ..We present two cases of cardiac myxoma diagnosed during pregnancy and review the presentation and management strategies of previously reported cases...
  78. pmc Familial cardiac myxoma: Carney's complex
    Asha Mahilmaran
    Institute for Cardiac Treatment and Research, Southern Railway Hospital, Ayanavaram, Chennai 600023, India
    Tex Heart Inst J 30:80-2. 2003
    ..in a 12-year-old boy who had the characteristic features of multiple cutaneous tumors, pigmentation, and biatrial myxoma. His large right atrial myxoma almost occluded the tricuspid valve and presented a life-threatening emergency...
  79. ncbi The appearance of Mazabraud's syndrome on 18F-FDG PET/CT
    Amit Singnurkar
    Department of Nuclear Medicine, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine Road, Montreal, Quebec, H3T 1E2 Canada
    Skeletal Radiol 36:1085-9. 2007
    ..3 and 2.6. As such, this entity merits consideration when evaluating hypoattenuating intramuscular masses, particularly in the context of fibrous dysplasia...
  80. ncbi Orbital myxoma--an unusual cause of inferoorbital mass
    S L Ting
    Department of Ophthalmology, Faculty of Medicine and Health Sciences, Universiti Malaysia Sarawak, 77, Seksyen 22, KTLD, Jalan Tun Ahmad Zaidi Adruce, 93150, Kuching, Sarawak, Malaysia
    Med J Malaysia 65:224-6. 2010
    ..To describe a case of isolated infraorbital mass which had been present for the past 9 years in a young woman. Despite the size, the mass was successfully excised in total...
  81. ncbi Multiple cerebral mycotic aneurysms due to left atrial myxoma: are there any pitfalls for the cardiac surgeon?
    Nikolaos G Baikoussis
    Cardiac Surgery Department, University Hospital, Ioannina School of Medicine, Ioannina, Greece
    Hellenic J Cardiol 52:466-8. 2011
    ..atrial myxomas has been well documented, but the formation of multiple cerebral aneurysms resulting from atrial myxoma is a very rare neurological complication...
  82. pmc Left atrial myxoma with papillary fibroelastoma-like features
    Abbas Agaimy
    Institute of Pathology, Friedrich Alexander University Erlangen Nuremberg, Germany
    Int J Clin Exp Pathol 4:307-11. 2011
    Although rare, papillary fibroelastoma (PFE) of the heart valves and atrial myxoma represent the two most common cardiac tumors. Coexistence of these two lesions has been documented in rare case reports...
  83. ncbi Myxoma of the jaws. Report of three cases
    G Hernandez Vallejo
    Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontologia, Universidad Complutense, Madrid, Espana
    Med Oral 6:106-13. 2001
    Odontogenic myxoma is a locally aggressive, uncommon benign tumour which arises from mesenchymal tissues normally present in developing teeth...
  84. ncbi An atypical left atrial myxoma causing intracavitary pressure gradient and typical diastolic transmitral flow of severe mitral stenosis
    John T Parissis
    Int J Cardiol 102:165-7. 2005
  85. ncbi Cerebral embolism from left atrial myxoma leading to cerebral and retinal aneurysms: a case report
    Martin Herbst
    Department of Neurology, University of Bonn, Bonn, Germany
    AJNR Am J Neuroradiol 26:666-9. 2005
    Left atrial myxoma commonly leads to cerebral embolic ischemic stroke...
  86. ncbi Robotic excision of atrial myxoma
    Jonathan Schilling
    Department of Surgery, Good Samaritan Hospital, Cincinnati, Ohio, USA
    J Card Surg 27:423-6. 2012
    ..System have facilitated minimally invasive and robotic cardiac procedures including mitral valve repair and atrial myxoma excision...
  87. ncbi Trends in the clinical and morphological characteristics of cardiac myxoma: 20-year experience of a single tertiary referral center in Japan
    Satoshi Yuda
    Department of Cardiology, National Cardiovascular Center, Osaka, Japan
    Circ J 66:1008-13. 2002
    The purpose of this study was to clarify whether or not a change in the clinical characteristics of cardiac myxoma has occurred during the past 2 decades...
  88. ncbi Local thrombolysis for successful treatment of acute stroke in an adolescent with cardiac myxoma
    Natig Gassanov
    Department of Internal Medicine III, University of Cologne, Germany
    ScientificWorldJournal 11:891-3. 2011
    ..The mass was excised surgically, confirmed as a benign atrial myxoma, and the patient was discharged with restitution ad integrum...
  89. ncbi PRKAR1A gene mutation in patients with cardiac myxoma
    T Mabuchi
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Takara machi 13 1, Kanazawa 920 8640, Japan
    Int J Cardiol 102:273-7. 2005
    ..dominant multiple neoplasia syndrome characterized by spotty pigmentations, endocrine overactivity and cardiac myxoma. We hypothesized that cardiac myxoma may be associated with PRKAR1A gene mutation and determined whether mutation ..
  90. ncbi Corneal myxoma arising in a patient with repeated phototherapeutic keratectomies
    Jennifer W Robinson
    Department of Ophthalmology, University of Ottawa Eye Institute and The Ottawa Hospital, Ottawa, Ontario, Canada
    Cornea 25:1111-4. 2006
    We report the clinical and pathologic findings of a corneal myxoma that was diagnosed in a cornea that had undergone phototherapeutic keratectomy (PTK).
  91. ncbi Surgical management of cardiac myxoma
    Gokhan Ipek
    Kosuyolu Heart and Research Hospital, Istanbul, Turkey
    J Card Surg 20:300-4. 2005
    Between 1994 and December 2003, 55 patients were operated for cardiac myxoma in Kosuyolu Heart and Research Hospital in Istanbul.
  92. ncbi Interleukin-6 and "complex" cardiac myxoma
    Y Mochizuki
    Department of Thoracic and Cardiovascular Surgery, Dokkyo University School of Medicine, Tochigi, Japan
    Ann Thorac Surg 66:931-3. 1998
    A rare case of "complex" cardiac myxoma is reported. Complex cardiac myxoma manifests with more constitutional signs than the sporadic type...
  93. ncbi Left atrial and right ventricular myxoma: an uncommon presentation of a rare tumour
    Andres Diaz
    Cardiothoracic Unit, University College Hospital, The Heart Hospital, London, UK
    Interact Cardiovasc Thorac Surg 12:622-3. 2011
    ..Transoesophageal echocardiography has become an invaluable tool to diagnose myxomas and plan the surgical approach...
  94. ncbi Sinonasal myxoma: a pediatric case
    Latha Prasannan
    Department of Pediatrics, Scott and White Hospital and The Texas A and M University System Health Science Center College of Medicine, Temple, Texas 76508, USA
    J Pediatr Hematol Oncol 27:90-2. 2005
    The authors report a case of a rare facial myxoma arising from the maxillary sinus in a 20-month-old child...
  95. pmc Clinical experiences of cardiac myxoma
    Song Hyeon Yu
    Department of Thoracic and Cardiovascular Surgery, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 47:367-71. 2006
    Although cardiac myxoma is rare, it is the most common primary cardiac tumor. Seventy-four cases of cardiac myxoma that were surgically treated in our center between August 1980 and February 2005 were retrospectively reviewed...
  96. pmc Complete embolization of a left atrial myxoma resulting in acute lower extremity ischemia
    Chris Coley
    Department of Vascular and Endovascular Surgery, Orlando Regional Medical Center, Orlando, Florida 32806, USA
    Tex Heart Inst J 32:238-40. 2005
    Atrial myxoma is the most common benign tumor of the heart. Patients who have atrial myoxmas usually present with cardiac obstruction, arrhythmias, or peripheral embolization...
  97. ncbi A rare case of aortic valve myxoma: an unusual cause of embolic stroke
    Shiva Prasad Koyalakonda
    University Hospital Aintree, Liverpool, UK
    Cardiology 118:101-3. 2011
    Aortic valve myxoma is an extremely rare cardiac tumour. We describe a 60-year-old woman found to have an aortic valve myxoma and a patent foramen ovale (PFO) presenting as a stroke...
  98. ncbi Resection of left ventricular myxoma after embolic stroke
    Marcus Vinicius Ferraz de Arruda
    Hospital dos Fornecedores de Cana, Avenida Barão de Valença 716, Piracicaba
    Rev Bras Cir Cardiovasc 23:578-80. 2008
    Cardiac myxoma is the most common primary tumor of the heart. The tumor is located mainly in the left atrium but can arise from any heart chamber. Clinical symptoms are variable but dyspnea and embolism are the most frequent...
  99. ncbi Surgical treatment of primary intracardiac myxoma: 19 years of experience
    George Samanidis
    2nd Department of Adult Cardiac Surgery, Onassis Cardiac Surgery Center, Athens, Greece
    Interact Cardiovasc Thorac Surg 13:597-600. 2011
    Cardiac myxoma is the most common benign tumor of the heart. It presents with a variety of clinical signs and symptomatology making diagnosis frequently quite a challenge...
  100. ncbi Aggressive angiomyxoma of the vulva
    R Ribaldone
    Clinics of Gynecology and Obstetrics, Maggiore Hospital of Novara, Department of Medical Sciences, University of Eastern Piedmont, Corso Mazzini 18, Novara, Italy
    Gynecol Oncol 95:724-8. 2004
    ..Aggressive angiomyxoma is a rare soft tissue tumour that carries a high risk of local relapse. It is a slowly growing and locally infiltrating tumour...
  101. ncbi Sinonasal myxoma in an infant
    Ioannis A Iatrou
    University Department of Oral and Maxillofacial Surgery, Dental School of Athens, Greece
    J Craniofac Surg 21:1649-51. 2010
    ..region are neoplastic entities of mesenchymal origin most often associated with odontogenic origin; sinonasal myxoma is rare, located in the nasolabial region and originating from the sinonasal tract...

Research Grants23

  1. Serpin Modulation of Inflammatory Vasculitis; Potential for Immunomodulatory Ther
    ALEXANDRA ROSE LUCAS; Fiscal Year: 2010
    ..Two innovative therapeutic approaches, based upon the infusion of serpins, one derived from a myxoma virus, Serp-1, and one mammalian serpin, neuroserpin (NSP), have been investigated in our research laboratory with ..
  2. Host defense against poxviruses and viral immune evasion
    Liang Deng; Fiscal Year: 2011
    ..We found that attenuated vaccinia or myxoma (a rabbit poxvirus) infection of dendritic cells and macrophages trigger autophagy, whereas wild-type vaccinia ..
  3. Myxoma Virus (MV) Oncolysis for treating human cancer
    Grant McFadden; Fiscal Year: 2013
    Project Summary Myxoma virus (MV) infects only rabbits in vivo, but also has a natural capacity to infect a wide variety of human cancer cells in vitro and in vivo...
  4. Manipulation of inflammasomes and NF-kB signaling in human myeloid cells by Myxom
    Grant McFadden; Fiscal Year: 2013
    ..downstream innate immune responses via inflammasomes and NF-?B signaling in determining the tropism and sensing of myxoma virus (MYXV), a rabbit specific poxvirus that also exhibits the capacity to infect a wide spectrum of human cancer ..
  5. Virotherapy for pancreatic cancer with wildtype and armed Myxoma viruses
    Grant McFadden; Fiscal Year: 2012
    ..abstract_text> ..
  6. Studies in Poxvirus Host Range Genes and Tropism
    Grant McFadden; Fiscal Year: 2013
    ..examine the molecular pathways that mediate the species specificity and tropism of one particular poxvirus, namely myxoma virus (MV)...
  7. Characterization of Antiviral Functions of Sterile Alpha Motif-Containing Domain
    Jia Liu; Fiscal Year: 2013
    ..from this study will provide detail descriptions on their action using infection models by two DNA viruses, myxoma virus (MYXV) and herpes simplex virus type 1 (HSV-1)...
  8. Genomic analysis of the canonical case of virulence evolution: Myxomatosis in Au
    Andrew F Read; Fiscal Year: 2013
    ..risk? In this proposal we seek to determine the molecular genetic basis of the evolution of the highly lethal myxoma virus after it was deliberately released as a biocontrol agent against rabbits in both Australia and Europe in the ..
  9. Treatment of transplanted and established multiple myeloma using oncolytic myxoma
    ERIC CARTER BARTEE; Fiscal Year: 2013
    ..Currently, I am interested in the study of a rabbit specific poxvirus called myxoma virus (MYXV) and how it interacts with normal and cancerous cells...
  10. GENE REGULATION OF MAMMALIAN DNA VIRUSES
    Richard Moyer; Fiscal Year: 2005
    ..The leporipoxvirus myxoma virus (MYX) encodes two functional serpins: SERP1 and SERP2...
  11. REGULATION OF P53 EXPRESSION BY C7 TRANSCRIPTION FACTOR
    David Strayer; Fiscal Year: 1999
    ..The applicant's laboratory has discovered that a transcription factor from a malignant rabbit myxoma virus, namely C7, regulates p53 mRNA levels and negatively affects cell proliferation, notably of lymphocytes...
  12. Viral PYRIN-only proteins as suppressors of the host immune response
    Christian Stehlik; Fiscal Year: 2007
    ..novel immunoevasive strategy of poxviruses also by gene ablation of the viral PYRIN-only protein of the rabbit myxoma virus, a widely used model for the poxvirus family, and assessment of host cell infection efficiency. (Aim 2)...
  13. Immune evasion by gamma 2 Herpesviruses
    KLAUS J FRUEH; Fiscal Year: 2010
    ..abstract_text> ..
  14. Antiviral host responses by cytomegalovirus
    Klaus Frueh; Fiscal Year: 2005
    ..The major goals of this proposal include identification of 1) RhCMV gene(s) required for ISG downregulation and 2) host pathways targeted by the virus to accomplish this. ..
  15. Functional characterization of the poxviral RING protein
    Klaus Frueh; Fiscal Year: 2006
    ..In addition, the proteomics approaches are expected to provide new tools for the study of ubiquitination events in virally infected cells. ..
  16. Mechanisms of T cell Escape by Orthopoxviruses
    Klaus Frueh; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  17. A novel family of transmembrane ubiquitin ligases
    Klaus Frueh; Fiscal Year: 2005
    ..abstract_text> ..
  18. DYSRHYTHMIAS OF THE RESPIRATORY OSCILLATOR
    David Paydarfar; Fiscal Year: 2002
    ....
  19. ROLE OF THE CNC GENE IN DEVELOPMENT AND TUMORIGENESIS
    LAWRENCE KIRSCHNER; Fiscal Year: 2004
    ..The long-term goal of this project is to identify the role that the CNC gene product plays in the normal development of the endocrine and other systems, as well as the role that the mutated gene plays in tumorigenesis. ..
  20. Carney Complex: A Model for PKA-Mediated Tumorigenesis
    LAWRENCE KIRSCHNER; Fiscal Year: 2008
    ..abstract_text> ..
  21. Physiology of Swallowing and Airway Protection
    David Paydarfar; Fiscal Year: 2006
    ..We will stimulate the ISLN (using optimum parameters from Aim 3) in patients with neurogenic dysphagia caused by focal cerebral damage, and we will test for improvement in swallowing and decrease in aspiration. ..
  22. Cardiac MDCT for Early Triage of Patients with ACS
    Udo Hoffmann; Fiscal Year: 2008
    ..abstract_text> ..
  23. In vivo Ribosome Tagging in Neuroendocrine Cell Types
    PAUL AMIEUX; Fiscal Year: 2008
    ..Low, medium, and highly translated mRNAs expressed in specific neuroendocrine cell types under varying physiological states can then be analyzed on microarrays followed by Quantitative-PCR. [unreadable] [unreadable]..