fibroma

..We report here a case of pulmonary valve papillary fibroelastoma that was successfully managed with simple excision of the mass...

We report a very rare case of fibroma of the tendon sheath arising from the anteromedial ankle joint capsule, with no apparent connection to any tendon in the area, found in a 58-year-old patient complaining of progressive local swelling...

..Intralesional therapy with corticosteroids did not reduce the lesions. After surgical treatment, the lesions recurred...

..We review clinical characteristics, diagnostic difficulties, and our experience in the surgical management of ovarian fibromas...

Chondromyxoid fibroma is an uncommon benign cartilaginous tumor accounting for less than 1% of all bone tumors...

OBJECTIVE: The aim of this case report was to analyze clinical and histological features of a central odontogenic fibroma followed up for 6 years after surgical excision...

..The microscopic diagnosis was a fibroma, which is a rare entity in this location...

We report a rare case of fibroma of the tendon sheath arising from the fat pad in the knee. To our knowledge, only four previous cases of fibroma of the tendon sheath in the knee have been reported in the English literature...

..b>Fibroma and thecoma seem to be different neoplasms and should be considered distinct, separate entities because they have ..

b>Fibroma of tendon sheath is an uncommon benign soft tissue tumor with a predilection for the hand. A unique case involving the scapholunate and radiocarpal joints with bone erosion is reported...

..The objective of the study was to identify the incidence, diagnosis, and therapeutic and histological particularities of ovarian fibromas and fibrothecomas...

..imaging-including ultrasound, computed tomography, and magnetic resonance imaging-and histological features of a fibroma of the tendon sheath with mineralized chondroid and osseous metaplasia, presenting as a semimembranosus bursitis...

..both a diffuse sclerotic border and calcified bodies, which was eventually diagnosed as a central odontogenic fibroma. The patient was a 40-year-old man with a painless radiolucent area in the crown area of the unerupted left lower ..

Nuchal-type fibroma, first described in 1988 by Enzinger and Weiss, is a rare fibrous growth occurring predominantly in the interscapular and paraspinous regions...

Odontogenic fibroma (ODF) is a rare odontogenic tumor. It can be further divided into peripheral odontogenic fibroma (PODF) and central odontogenic fibroma (CODF)...

Chondromyxoid fibroma constitutes a rare benign tumor of the bones, which has a potential of regional enlargement towards the local tissues...

..Perioperative observation revealed that the tumor was partly adhesive to the anterior knee joint capsule, but not to the patellar tendon...

..It can be easily diagnosed on computed tomography or magnetic resonance images and should not be mistaken for a malignant tumor...

..Histology from the specimen was consistent with elastofibroma dorsi with free resection margins...

..Differential diagnosis of this unusual variant of metaplastic breast carcinoma is discussed together with related therapeutic issues...

..Although bilateral involvement of the thighs is exceptional, the presence of concomitant characteristic bilateral subscapular lesions was helpful in making the diagnosis of elastofibroma...

..We report here case of SFT arising from the tongue of a 75-year-old woman. To our knowledge, this is the second case reported of SFT originating from the tongue...

..In conclusion, SAFM represents a distinct entity in the spectrum of cutaneous myxoid tumors. The differential diagnosis of SAFM includes various myxoid neoplasms and tumors with a predilection for distal parts of the extremities...

..The histopathologic diagnosis was papillary fibroelastoma. When a tumor of the aortic valve exists, these examinations are useful in detecting and characterizing the tumor for optimal treatment...

..Asymptomatic patients with nonmobile CPF could be followed-up closely with periodic clinical evaluation and echocardiography, and receive surgical intervention when symptoms develop or the tumor becomes mobile...

..The patient was treated surgically for the prevention of further embolic complications. Pertinent literature is also reviewed for this rare and benign cardiac tumor...

..At the autopsy a large papillary fibroelastoma of the aortic valve was found. This probably produced intermittent obstruction of the coronary artery ostia...

Odontogenic fibroma (OF) is a rare benign odontogenic tumor deriving from the dental mesenchymal tissue and accounting for less than 5% of all odontogenic tumors...

..The expression of CD34 antigen and vimentin were useful for the differential diagnosis...

..When the lesion exhibits typical imaging features and produces no symptoms, as is usually the case, further investigations are probably unnecessary...

Central odontogenic fibroma is an extremely rare benign tumor, accounting for less than 0.1% of all odontogenic tumors...

..We report six cases of elastofibroma dorsi, the clinical presentation and radiology findings are reviewed and compared with literature...

..We report a case of the simultaneous occurrence of both conditions in the same individual. To our knowledge, this has not been previously described. The clinical course has been slow, progressive, and recalcitrant to treatment...

..Smooth muscle actin and S-100 protein are negative. Electron microscopy shows uniform neoplastic spindle cells with mesenchymal features. The differential diagnosis for spindle cell neoplasms in the tongue is discussed...

Collagenous fibroma (desmoplastic fibroblastoma) is an extremely rare benign soft tissue tumor of fibroblastic origin...

..The differential diagnosis includes frequently observed subcutaneous neoplasms such as lipoma, fibrolipoma or more aggressive tumors. The diagnosis is made with histologic examination...

..0 cm in diameter. While myxomas commonly arise from the interatrial septum, we present the rare example of a large papillary fibroelastoma arising from the left side of the interatrial septum...

..We report an odontogenic tumor that was composed of calcifying odontogenic cyst and ameloblastic fibroma that occurred in the right posterior maxilla of a 22-year-old Korean woman...

..In addition, the use of imatinib mesylate in the treatment of this neoplasm preferably should be in the context of a formal prospective clinical trial...

..We report an unusual case of multiple papillary fibroelastomas in a woman, who initially was admitted because of a shortness of breath and recent cerebrovascular accident...

..The authors present a case of Meigs syndrome with an ovarian fibroma. They focus on the evaluation of pleural fluid in the setting of an ovarian mass and then briefly discuss the ..

Thirty-four cases of ovarian fibroma are reported. The early symptoms were pelvic pain and abnormal uterine bleeding...

Calcifying aponeurotic fibroma is a rare, benign soft-tissue proliferation that occurs in the distal extremities in children...

..A cyst with an important inflammatory infiltrate was, moreover, observed...

..Therefore, the less expensive ultrasound diagnosis, as a major method of screening for elastofibroma dorsi, would seem to be a reasonable proposal...

..In conclusion, iatrogenic PFEs may be relatively common among all such tumors, are frequently multiple, and often involve nonvalvular endocardial surfaces...

..Loss of heterozygosity findings in the PTCH locus and increased expression of several genes in the pathway strongly suggest that the pathway is involved in both ovarian fibroma and dermoids.

..was reconstructed after a partial ventriculectomy Histologic investigation showed a completely resected benign fibroma. The 30-year-old mother was known to have nevoid basal-cell carcinoma syndrome, which can be associated with ..

Infantile digital fibroma (IDF) is a rare benign fibrous tumor of childhood that frequently recurs despite local excision. Conservative, nonsurgical management may result in regression and/or joint deformity.

..This difference may account inpart for their divergent clinical manifestations despite their morphologic resemblance to deep fibromatoses...

..Because FLSpCCs may be underdiagnosed as benign, the use of immunohistochemical studies, especially for cytokeratins and SMA, is essential in the evaluation of any spindle cell proliferations of the breast...

..cytogenetic data indicate that gain of chromosome 9 in addition to gain of chromosome 12 is prominent in cellular fibroma. In contrast, loss of chromosomes 4 and/or 9 are recurrent in fibroma...

..We also include a comparison and brief review of the clinicopathologic and immunohistochemical features of other spindle cell tumors of the oral cavity, from which SFTs must be differentiated...

Chondroblastoma (CB) and chondromyxoid fibroma (CMF) are benign tumors of bone morphologically recapitulating cartilage differentiation. CMF can resemble high-grade central chondrosarcoma (HGCCS) because of its cellular atypia...

..Because of the potential for embolic events, symptomatic patients, patients undergoing cardiac surgery for other lesions, and those with highly mobile and large CPFs should be considered for surgical excision...

..We sought to determine the clinical and echocardiographic characteristics of papillary fibroelastoma (PFE)...

Chondromyxoid fibroma is a rare cartilage tumor that represents less than 1% of all bone tumors. When in a long bone, it is usually an intramedullary lesion that is eccentrically located in the metaphyseal region...

..Histologic staining, however, failed to reveal characteristic features of papillary fibroelastoma...

..Familiarity with these imaging features and with the relative effectiveness of these modalities is essential for prompt diagnosis and effective treatment...

We observed clonal chromosome abnormalities in two fibrous soft tissue tumors diagnosed as collagenous fibroma (desmoplastic fibroblastoma)...

..The microscopic examination demonstrated a papillary fibroelastoma. The unusual localization and management of papillary fibroelastomas are discussed...

..A 59-year-old woman with 2 previous strokes presented with a tumor in the left ventricular apex. The patient underwent tumor resection through a left ventriculotomy. The histopathologic diagnosis was papillary fibroelastoma...

Juvenile aponeurotic fibroma is a rare benign tumour which occurs mainly in young patients under 20 years of age and especially during childhood. Clinical presentation is a unique, hard and painless tumour of the palm or sole...

..Upon surgery, a tumor was found on each aortic cusp. Pathological findings of these tumors were consistent with those of papillary fibroelastoma...

..It is believed that this is the first reported instance of surgically resected and morphologically confirmed multiple PFEs seen and removed at one operation...

..We discuss the pathophysiology of fibroelastomas of the aortic valve and operative approaches to the management of these tumors when they are discovered incidentally...

..Diagnosis was made by transesophageal echocardiogram, and the tumor was resected surgically...

The clinicopathologic and immunohistochemical features of 69 pediatric examples of infantile digital fibroma/fibromatosis (IDF) were analyzed...

..Owing to the risk of embolic complications, surgery was emergently performed with complete resection of the mass and preservation of the mitral valve. Histological evaluation confirmed the diagnosis of CPF...

..The diagnosis is often missed prospectively. Familiarity with the location and imaging appearance of elastofibroma dorsi may enhance detection and characterization of posterolateral chest wall masses in elderly patients...

..The patient underwent repair of the mitral valve and excision of the pulmonic valve mass, which was confirmed as a papillary fibroelastoma by histology...

..To our knowledge, this is the first case report in the English literature of a patient with synchronous presentation of an osteoblastoma and fibromatosis...

..The majority of fibroelastomas have been described on the left side of the heart involving the aortic and mitral valves. We present a rare case of a papillary fibroelastoma occurring on the pulmonic valve...

..Selected soft tissue tumors will be described and illustrated with emphasis on these 5 elements...

..PEComas represent an enigmatic family of neoplasms composed of perivascular epithelioid, clear, and spindled tumour cells characterized by a coexpression of melanocytic and myogenic markers...

..Our experience encourages us to use the fiberscope when resecting other intracardiac masses, including thrombi...

..Papillary fibroelastoma is a rare, benign cardiac valve tumour, which can mimic conditions such as atrial myxoma and infective endocarditis...

..Digital fibromas are common benign acral tumors typically reported as angiofibromas (AFs) or acquired digital fibrokeratomas (ADFs). Cellular variants are not well recognized...

..This article provides an overview of examination protocols of MRI and CT for cases in which a cardiac mass is suspected and describes the appearance of primary and secondary cardiac masses as well as intracavitary thrombi...

..Metastases to the heart are usually approached symptomatically except for exceptional cases...

..We report an 8-month-old asymptomatic female infant with papillary fibroelastoma of the mitral valve, discovered by echocardiograph examination...

..Histological examination confirmed the diagnosis of a cardiac fibroma. Complete excision of cardiac fibromas, where possible, is advised and is associated with excellent survival.

..This article reviews the pathological classification of cardiac and pericardial neoplasms, the incidence of the various tumor types, and the role of CT and MRI, including their major differences and clinical impact on patient management...

..For symptomatic patients surgical excision is curative...

..The echocardiographic characteristics along with treatment options are reviewed...

..This case is unusual with respect to the size and site of origin of the papillary fibroelastoma as well as its echocardiographic presentation mimicking vegetations on a pacemaker wire...

..The differential diagnosis of SFT in the central nervous system from fibrous meningioma and hemangiopericytoma requires immunohistochemistry and electron microscopy...

..heterozygotes do any adenomas form that retain an active, functional wildtype Apc allele? Aim Ic Does desmoid fibroma formation in Mid+ heterozygotes also involve loss of the wildtype Apc allele? Aim Id: Does the silencing pathway ..

..We propose to study the pathogenesis of malignant fibromatosis elicited by malignant rabbit fibroma virus (MV) as a function of the virus ability to manipulate apoptosis and cell cycle progression...

..In this grant we will develop a clinically robust classifier of molecular subtypes of leiomyosarcoma, improve outcome prediction, and identify novel potential treatment options for LMS. ..

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..Targeted therapeutic intervention to eliminate pathogens prior to clinical expression of AP could mitigate periodontal destruction, minimize functional and esthetic problems related to tooth loss, and reduce the cost of dental care. ..

..We expect that this will lead to an increased pace of discovery of pathogens implicated in disease, as well as genes of biological and biomedical importance. ..

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..Such a model could directly impact the prevention, diagnosis, and treatment of this devastating human disease. ..

..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..

..The receptors for this cytokine on normal and OA chondrocytes will be quantitated. Further definition of these cartilage metabolic pathways are of primary importance in our understanding of osteoarthritis...

..Ultimately, this work could facilitate new approaches for treating infections by A.a. and other pathogens that resist phagocytic killing (e.g., Salmonella and Chlamydia). ..

..It is further speculated that the study of serine proteinases produced by OA cartilage may have strong implications for the management of this debilitating disease. ..

..Apart from the worldwide market, the potential market in United States alone should exceed $1,500,000 per year. ..

..Strategies that optimize the uptake and distribution of antimicrobial agents should enhance the elimination of invasive pathogens from the periodontium and other types of mucosa. ..

..Additional training and focused research in virology would allow Dr. Rose to expand upon his initial discovery and make further significant contributions in the fields of herpesviruses and viral pathogenicity. ..

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..By obtaining a K award, the PI will have the opportunity to develop skills for patient- oriented research under the direction of basic and clinical science mentors. ..

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