menorrhagia

Summary

Summary: Excessive uterine bleeding during MENSTRUATION.

Top Publications

  1. ncbi Levonorgestrel intrauterine system versus medical therapy for menorrhagia
    Janesh Gupta
    School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom
    N Engl J Med 368:128-37. 2013
  2. ncbi Low-dose mifepristone in treatment of uterine leiomyoma: a randomised double-blind placebo-controlled clinical trial
    Madhu Bagaria
    Department of Obstetrics and Gynaecology, University College of Medical Sciences, Delhi, India
    Aust N Z J Obstet Gynaecol 49:77-83. 2009
  3. ncbi Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resection
    Ilkka Rauramo
    The Finnish Medical Society Duodecim, Helsinki, Finland
    Obstet Gynecol 104:1314-21. 2004
  4. ncbi Age and the prevalence of bleeding disorders in women with menorrhagia
    Claire S Philipp
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Obstet Gynecol 105:61-6. 2005
  5. ncbi The experience of heavy menstrual bleeding: a systematic review and meta-ethnography of qualitative studies
    Ruth Garside
    PenTAG, Peninsula Medical School, Exeter, UK
    J Adv Nurs 63:550-62. 2008
  6. ncbi The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids
    Gaylene Pron
    Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 79:120-7. 2003
  7. ncbi The levonorgestrel-releasing intrauterine system in heavy menstrual bleeding: a benefit-risk review
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, FL 32209, USA
    Drugs 72:193-215. 2012
  8. ncbi Menorrhagia I: measured blood loss, clinical features, and outcome in women with heavy periods: a survey with follow-up data
    Pamela E Warner
    Division of Community Health Sciences, University of Edinburgh Medical School, Obstetrics and Gynaecology, University of Edinburgh, Centre for Reproductive Biology, Edinburgh, Scotland, United Kingdom
    Am J Obstet Gynecol 190:1216-23. 2004
  9. ncbi Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trial
    Josep Ll Carbonell Esteve
    Mediterránea Médica Clinic, Valencia, Castello, Valencian Country, Spain
    Eur J Obstet Gynecol Reprod Biol 161:202-8. 2012
  10. pmc Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysis
    J P Daniels
    University of Birmingham, Clinical Trials Unit, Birmingham B15 2TT, UK
    BMJ 344:e2564. 2012

Detail Information

Publications293 found, 100 shown here

  1. ncbi Levonorgestrel intrauterine system versus medical therapy for menorrhagia
    Janesh Gupta
    School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom
    N Engl J Med 368:128-37. 2013
    b>Menorrhagia is a common problem, yet evidence to inform decisions about therapy is limited...
  2. ncbi Low-dose mifepristone in treatment of uterine leiomyoma: a randomised double-blind placebo-controlled clinical trial
    Madhu Bagaria
    Department of Obstetrics and Gynaecology, University College of Medical Sciences, Delhi, India
    Aust N Z J Obstet Gynaecol 49:77-83. 2009
    ..To evaluate the effect of low-dose mifepristone on leiomyoma-related symptoms, uterine and leiomyoma in women with symptomatic leiomyomata...
  3. ncbi Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resection
    Ilkka Rauramo
    The Finnish Medical Society Duodecim, Helsinki, Finland
    Obstet Gynecol 104:1314-21. 2004
    The purpose of this study was to compare the long-term efficacy of the levonorgestrel intrauterine system and transcervical resection of the endometrium in the treatment of menorrhagia.
  4. ncbi Age and the prevalence of bleeding disorders in women with menorrhagia
    Claire S Philipp
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Obstet Gynecol 105:61-6. 2005
    A study was conducted to evaluate the frequency and types of hemostatic defects occurring in adolescent and perimenopausal-age women diagnosed with menorrhagia.
  5. ncbi The experience of heavy menstrual bleeding: a systematic review and meta-ethnography of qualitative studies
    Ruth Garside
    PenTAG, Peninsula Medical School, Exeter, UK
    J Adv Nurs 63:550-62. 2008
    ..This paper is a report of a systematic review and meta-ethnography of the experience of heavy menstrual bleeding...
  6. ncbi The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroids
    Gaylene Pron
    Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 79:120-7. 2003
    ..To evaluate fibroid uterine volume reduction, symptom relief, and patient satisfaction with uterine artery embolization (UAE) for symptomatic fibroids...
  7. ncbi The levonorgestrel-releasing intrauterine system in heavy menstrual bleeding: a benefit-risk review
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, FL 32209, USA
    Drugs 72:193-215. 2012
    ..In conclusion, the LNG-IUS is an effective treatment option for women with HMB, including those with underlying organic pathology or bleeding disorders...
  8. ncbi Menorrhagia I: measured blood loss, clinical features, and outcome in women with heavy periods: a survey with follow-up data
    Pamela E Warner
    Division of Community Health Sciences, University of Edinburgh Medical School, Obstetrics and Gynaecology, University of Edinburgh, Centre for Reproductive Biology, Edinburgh, Scotland, United Kingdom
    Am J Obstet Gynecol 190:1216-23. 2004
    b>Menorrhagia is defined as blood loss of >80 mL, but in routine clinical practice measurement is seldom undertaken. Our aim was to identify the features of the clinical history that best predict menorrhagic blood loss.
  9. ncbi Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trial
    Josep Ll Carbonell Esteve
    Mediterránea Médica Clinic, Valencia, Castello, Valencian Country, Spain
    Eur J Obstet Gynecol Reprod Biol 161:202-8. 2012
    ..To evaluate the efficacy and safety of 5 and 10mg doses of mifepristone for 6 months for the treatment of uterine fibroids and to check those results at 1 year post-treatment...
  10. pmc Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysis
    J P Daniels
    University of Birmingham, Clinical Trials Unit, Birmingham B15 2TT, UK
    BMJ 344:e2564. 2012
    ..To determine the relative effectiveness of second generation ablation techniques in the treatment of heavy menstrual bleeding...
  11. ncbi Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia: a randomized, prospective, controlled clinical trial in female smokers
    T Kucuk
    Department of Obstetrics and Gynecology, GATA School of Medicine, Ankara, Turkey
    Clin Exp Obstet Gynecol 35:57-60. 2008
    To compare the efficacy of three progestin regimens in perimenopausal menorrhagia.
  12. ncbi Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagia
    A Kriplani
    Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
    Int J Gynaecol Obstet 97:190-4. 2007
    To evaluate the efficacy, acceptability, and possible side effects of a levonorgestrel-releasing intrauterine system for menorrhagia.
  13. ncbi Work loss associated with increased menstrual loss in the United States
    Isabelle Côté
    Institute of Health Economics, Edmonton, Alberta, Canada
    Obstet Gynecol 100:683-7. 2002
    ..To estimate the effect of increased menstrual flow on the loss of work...
  14. pmc Why women consult with increased vaginal bleeding: a case-control study
    Mark Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire
    Br J Gen Pract 52:108-13. 2002
    ....
  15. ncbi Platelet functional defects in women with unexplained menorrhagia
    C S Philipp
    Division of Hematology and Women s Health Institute, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    J Thromb Haemost 1:477-84. 2003
    b>Menorrhagia is a common clinical problem and is unexplained in more than 50% of women...
  16. ncbi Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial
    Jeffrey T Jensen
    Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
    Obstet Gynecol 117:777-87. 2011
    ....
  17. ncbi Levonorgestrel-releasing intrauterine system and endometrial ablation in heavy menstrual bleeding: a systematic review and meta-analysis
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Florida, USA
    Obstet Gynecol 113:1104-16. 2009
    ..To compare the effects of the levonorgestrel intrauterine system and endometrial ablation in reducing heavy menstrual bleeding...
  18. ncbi Determination of total menstrual blood loss
    K M Wyatt
    Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital, Stoke-on-Trent, United Kingdom
    Fertil Steril 76:125-31. 2001
    ..SETTING: Academic menorrhagia research clinic...
  19. pmc Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients
    L J Middleton
    Birmingham Clinical Trials Unit, University of Birmingham, Birmingham B15 2TT
    BMJ 341:c3929. 2010
    ....
  20. ncbi Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: a randomized controlled trial
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA
    Obstet Gynecol 116:625-32. 2010
    ..To compare the efficacy and safety of the levonorgestrel-releasing intrauterine system and oral medroxyprogesterone acetate in the treatment of idiopathic heavy menstrual bleeding...
  21. pmc An epidemiological survey of symptoms of menstrual loss in the community
    Mark Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire
    Br J Gen Pract 54:359-63. 2004
    ..The evidence for this advice is based on the prevalence of symptoms in women with gynaecological malignancy or within specialist clinics. There are no studies on the incidence of symptoms within the community...
  22. ncbi Factor VII Deficiency
    Guglielmo Mariani
    Dipartimento di Medicina Interna e Sanita Pubblica, Universita dell Aquila, L Aquila 67010, Italy
    Semin Thromb Hemost 35:400-6. 2009
    ..In females, menorrhagia is prevalent and affects two thirds of the patients of fertile age...
  23. ncbi Effective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind Phase III trial
    I S Fraser
    Department of Obstetrics and Gynaecology, Central Clinical School, D02 QEII Research Institute for Mothers and Infants, University of Sydney, Sydney, NSW 2006, Australia
    Hum Reprod 26:2698-708. 2011
    ..This double-blind trial investigated the efficacy and safety of estradiol valerate/dienogest (E(2)V/DNG) for the treatment of heavy menstrual bleeding without recognizable organic pathology...
  24. ncbi A Scottish postal survey suggested that the prevailing clinical preoccupation with heavy periods does not reflect the epidemiology of reported symptoms and problems
    Miriam Santer
    Tayside Centre for General Practice, Mackenzie Building, Dundee, UK
    J Clin Epidemiol 58:1206-10. 2005
    ..To determine the prevalence of self-reported menstrual symptoms and problem periods and explore their relationship with sociodemographic factors, parity, long-standing illness, and hormonal contraceptive use...
  25. ncbi Levonorgestrel-releasing intrauterine system compared to low dose combined oral contraceptive pills for idiopathic menorrhagia: a randomized clinical trial
    Mamdouh M Shaaban
    Faculty of Medicine, Department of Obstetrics and Gynecology, Assiut University, Assiut 71526, Egypt
    Contraception 83:48-54. 2011
    This study compared the efficacy of the levonorgestrel-releasing intrauterine system (LNG-IUS) to low dose combined oral contraceptive pills (COC) in the management of idiopathic menorrhagia.
  26. ncbi A Canadian, multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagia
    Jan Endrikat
    Bayer Inc, Toronto, Ontario, Canada
    J Obstet Gynaecol Can 31:340-7. 2009
    ..intrauterine system (LNG-IUS) compared with a combined oral contraceptive containing 1 mg norethindrone acetate and 20 mg ethinyl estradiol (OC1/20) in reducing menstrual blood loss (MBL) in women with idiopathic menorrhagia.
  27. ncbi Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, North Carolina 27713, USA
    Obstet Gynecol 116:865-75. 2010
    ..To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding...
  28. ncbi Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment charts
    Peter C Reid
    Luton and Dunstable NHS Trust, Luton, UK
    BJOG 112:1121-5. 2005
    To compare the efficacy and tolerability of the levonorgestrel intrauterine system (LNG IUS) with mefenamic acid in the management of objective idiopathic menorrhagia.
  29. ncbi The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre
    S Mikhail
    Department of Medicine, Rochester General Hospital, 1415 Portland Avenue, Rochester, NY 14621, USA
    Haemophilia 13:627-32. 2007
    b>Menorrhagia at the time of menarche is relatively common and historically attributed primarily to immaturity of the pituitary-ovarian-uterine axis...
  30. ncbi Treatment of menorrhagia with an LNG-IUS
    Paivi Pakarinen
    Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, PO Box 140, HUCH, 00029, Finland
    Contraception 75:S118-22. 2007
    b>Menorrhagia, also known as heavy menstrual bleeding, is defined as a menstrual blood loss is greater than 80 mL...
  31. ncbi Can the levonorgestrel intrauterine system replace surgical treatment for the management of menorrhagia?
    Rani Nagrani
    Department of Obstetrics and Gynaecology, Singleton Hospital, Swansea, UK
    BJOG 109:345-7. 2002
    b>Menorrhagia is a common gynaecological condition for which medical treatment is often ineffective and a large number of women undergo major surgery...
  32. ncbi Efficacy of the levonorgestrel intrauterine system in treating menorrhagia: actualities and ambiguities
    Amaju Ikomi
    Department of Obstetrics and Gynaecology, Basildon Hospital, Essex, UK
    J Fam Plann Reprod Health Care 28:99-100. 2002
    ..Data extraction and synthesis: After perusal, each relevant publication was summarised and appraised in terms of whether it contained information relevant to the stated objective...
  33. ncbi Menorrhagia due to abnormalities of the platelet function: evaluation of two young patients
    Yesim Aydinok
    Division of Pediatric Hematology, Department of Pediatrics, School of Medicine, Ege University, Izmir, Turkey
    Pediatr Int 49:106-8. 2007
  34. ncbi A cost-utility analysis of hysterectomy, endometrial resection and ablation and medical therapy for menorrhagia
    Joyce H S You
    Centre for Pharmacoeconomics Research, School of Pharmacy, The Chinese University of Hong Kong, China
    Hum Reprod 21:1878-83. 2006
    ..intrauterine system (LNG-IUS) and oral medical therapy] are available for management of menorrhagia. The objective of this study was to compare the cost and quality-adjusted life-years (QALYs) gained by these ..
  35. ncbi Improving results of hysteroscopic submucosal myomectomy for menorrhagia by concomitant endometrial ablation
    Franklin D Loffer
    Department of Obstetrics and Gynecology, University of Arizona, Phoenix, Arizona 85013, USA
    J Minim Invasive Gynecol 12:254-60. 2005
    To evaluate the effect of endometrial ablation on the outcome of premenopausal patients undergoing hysteroscopic myomectomy for menorrhagia or menometrorrhagia
  36. ncbi Bleeding disorders in teenagers presenting with menorrhagia
    Yasmin Jayasinghe
    Department of Paediatric and Adolescent Gynaecology, Royal Children s Hospital, Melbourne, Australia
    Aust N Z J Obstet Gynaecol 45:439-43. 2005
    ..To assess the prevalence of bleeding disorders and establish the clinical variables that are predictive of a bleeding disorder in adolescent women...
  37. ncbi The Ontario Uterine Fibroid Embolization Trial. Part 1. Baseline patient characteristics, fibroid burden, and impact on life
    Gaylene Pron
    Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Fertil Steril 79:112-9. 2003
    ..To determine baseline characteristics of women undergoing uterine artery embolization (UAE) for symptomatic fibroids...
  38. ncbi Prognostic factors for the success of thermal balloon ablation in the treatment of menorrhagia
    M Y Bongers
    Department of Obstetrics and Gynecology, St Joseph Hospital, The, Veldhoven, Netherlands
    Obstet Gynecol 99:1060-6. 2002
    To identify predictive factors that will ensure successful menorrhagia treatment using hot fluid balloon endometrial ablation.
  39. ncbi Depressive symptoms as predictors of discontinuation of treatment of menorrhagia by levonorgestrel-releasing intrauterine system
    Marko Elovainio
    National Research and Development Centre for Welfare and Health, P O Box 220, FIN 00531, Helsinki, Finland
    Int J Behav Med 14:70-5. 2007
    It has been shown that levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment of menorrhagia. However, the discontinuation rate of LNG-IUS treatment is high, and little is known about the actual reasons ..
  40. ncbi Abnormal bleeding patterns associated with menorrhagia in women in the community and in women presenting to primary care
    Mark Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire ST5 5BG, UK
    Fam Pract 24:532-7. 2007
    There is an assumption that in women with menorrhagia 'excessive menstrual loss in regular cycles is the most common clinical presentation' yet epidemiological studies show irregular cycles and bleeding are common.
  41. ncbi Three-dimensional power Doppler study of endometrial and subendometrial microvascularization in women with intrauterine device-induced menorrhagia
    Akmal El-Mazny
    Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt
    Fertil Steril 99:1912-5. 2013
    ..microvascularization, using three-dimensional (3D) power Doppler ultrasound, in women with intrauterine device (IUD)-induced menorrhagia; and whether those potential findings could predict the risk of bleeding before IUD insertion.
  42. ncbi First- versus second-generation endometrial ablation devices for treatment of menorrhagia: a systematic review, meta-analysis and appraisal of economic evaluations
    Jamie Kroft
    Sunnybrook Health Sciences Centre, Department of Obstetrics and Gynaecology, University of Toronto, Toronto ON
    J Obstet Gynaecol Can 35:1010-9. 2013
    ..of using second-generation endometrial ablation devices compared to first-generation devices for treatment of menorrhagia in pre-menopausal women. The secondary objective was to compare the second-generation devices with one another.
  43. ncbi Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagia
    Claire S Philipp
    Division of Hematology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Am J Obstet Gynecol 204:209.e1-7. 2011
    The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.
  44. ncbi The spectrum of haemostatic characteristics of women with unexplained menorrhagia
    C H Miller
    Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Haemophilia 17:e223-9. 2011
    While an estimated 13% of women with unexplained menorrhagia have von Willebrand disease (VWD), the frequency of other potential bleeding disorders has been uncertain...
  45. ncbi Clinical practice guidelines on menorrhagia: management of abnormal uterine bleeding before menopause
    H Marret
    centre hospitalo universitaire de Tours, Hopital Bretonneau, Service de Gynecologie, Tours 37044 cédex 1, France
    Eur J Obstet Gynecol Reprod Biol 152:133-7. 2010
    Normal menstrual periods last 3-6 days and involve blood loss of up to 80ml. Menorrhagia is defined as menstrual periods lasting more than 7 days and/or involving blood loss greater than 80ml...
  46. ncbi Managing perimenopausal menorrhagia
    Kirsten Duckitt
    Medical Staff Office, Campbell River and District Hospital, Campbell River, British Columbia, Canada
    Maturitas 66:251-6. 2010
    b>Menorrhagia is a significant health problem for many women. It increases with age and peaks during the perimenopause...
  47. ncbi Adolescent menorrhagia due to platelet function disorder
    Nazli Hossain
    Department of Obstetrics and Gynecology Unit 3, Dow University of Health Sciences and Civil Hospital Karachi
    J Pak Med Assoc 60:127-9. 2010
    The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%...
  48. ncbi The cost-effectiveness of the levonorgestrel-releasing intrauterine system for the treatment of idiopathic heavy menstrual bleeding in the United States
    Michael L Ganz
    United BioSource Corporation, Lexington, MA 02420, USA
    Value Health 16:325-33. 2013
    ..Our objective was to evaluate the cost-effectiveness of the levonorgestrel-releasing intrauterine system (LNG-IUS) compared with other therapies for idiopathic heavy menstrual bleeding...
  49. ncbi An assessment of economic measures used in menorrhagia: a systematic review
    Sabina Sanghera
    Health Economics Unit, School of Health and Population Sciences, Public Health Building, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK Electronic address
    Soc Sci Med 98:149-53. 2013
    b>Menorrhagia', or heavy menstrual bleeding, is a common problem affecting women...
  50. ncbi von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagia
    A Dilley
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, GA, USA
    Obstet Gynecol 97:630-6. 2001
    To estimate the prevalence of von Willebrand disease and other bleeding disorders in women with and without diagnosed menorrhagia.
  51. ncbi Outcomes after rollerball endometrial ablation for menorrhagia
    C Dutton
    Department of Obstetrics and Gynecology, Kaiser Permanente Medical Center, Santa Clara, California, USA
    Obstet Gynecol 98:35-9. 2001
    OBJECTIVE: To evaluate the outcomes of women undergoing rollerball endometrial ablation for menorrhagia and to identify factors associated with those outcomes...
  52. ncbi Bleeding disorders: A common cause of menorrhagia in adolescents
    J A Bevan
    Department of Pediatrics, Section of Pediatric Hematology and Oncology, Medical College and Children's Hospital of Wisconsin, Milwaukee, WI 53201-2178, USA
    J Pediatr 138:856-61. 2001
    OBJECTIVE: To determine the frequency of underlying bleeding disorders in adolescents with menorrhagia. STUDY DESIGN: We retrospectively reviewed the charts of all girls, aged 10 to 19 years, who presented to our children's hospital for ..
  53. ncbi Levonorgestrel-releasing intrauterine system vs. endometrial thermal ablation for menorrhagia
    Theodoros D Theodoridis
    1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Periferiaki Odos Thessalonikis, N Efkarpia, Thessaloniki, Greece
    Hormones (Athens) 8:60-4. 2009
    To evaluate the efficacy of a Levonorgestrel-releasing Intrauterine System (LNG-IUS) in controlling menorrhagia in comparison with endometrial thermal rollerball ablation.
  54. ncbi A cost-utility analysis of microwave endometrial ablation versus thermal balloon endometrial ablation
    Mary M Kilonzo
    Health Economics Research Unit, University of Aberdeen, UK
    Value Health 13:528-34. 2010
    ..To evaluate the cost-effectiveness of microwave endometrial ablation (MEA) and thermal balloon endometrial ablation (TBALL) for heavy menstrual bleeding...
  55. ncbi Tranexamic acid: a review of its use in the management of menorrhagia
    Keri Wellington
    Adis International Limited, Auckland, New Zealand
    Drugs 63:1417-33. 2003
    ..In a number of small clinical studies in women with idiopathic menorrhagia, tranexamic acid 2-4...
  56. pmc Heavy menstrual bleeding: delivering patient-centred care
    Miriam Santer
    Br J Gen Pract 58:151-2. 2008
  57. pmc Efficacy of bipolar radiofrequency endometrial ablation vs thermal balloon ablation for management of menorrhagia: A population-based cohort
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Minim Invasive Gynecol 16:692-9. 2009
    ..To compare the efficacy of bipolar radiofrequency ablation (RFA) and thermal balloon ablation (TBA) using treatment failure and postprocedure amenorrhea as outcome measures...
  58. ncbi Screening women with menorrhagia for underlying bleeding disorders: the utility of the platelet function analyser and bleeding time
    C S Philipp
    Division of Hematology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Haemophilia 11:497-503. 2005
    b>Menorrhagia is a very common clinical problem among women of reproductive age and recent studies have suggested that underlying bleeding disorders, particularly von Willebrand's deficiency and platelet function defects, are prevalent in ..
  59. ncbi Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleeding
    A M Sambrook
    Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Aberdeen, UK
    BJOG 116:1038-45. 2009
    ..To compare the clinical outcomes of microwave endometrial ablation and thermal balloon ablation for the treatment of heavy menstrual bleeding...
  60. ncbi A randomised controlled trial comparing the Cavaterm endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleeding
    Jed Hawe
    Department of Obstetrics and Gynaecology, Countess of Chester Hospital, UK
    BJOG 110:350-7. 2003
    ..To compare the effectiveness of the Cavaterm thermal balloon endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleeding...
  61. ncbi Diagnosis and treatment of menorrhagia
    R Hurskainen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Acta Obstet Gynecol Scand 86:749-57. 2007
    ..In western countries, about 5% of women of reproductive age will seek help for menorrhagia annually...
  62. ncbi Increased vaginal bleeding: the reasons women give for consulting primary care
    M Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire, UK
    J Obstet Gynaecol 23:48-50. 2003
    ..This does not distinguish consulters and non-consulters and is not reflected in objective measures of psychological distress. Clinicians should focus initially on treating the presenting physical symptoms...
  63. ncbi Pictorial blood loss assessment chart in the evaluation of heavy menstrual bleeding: diagnostic accuracy compared to alkaline hematin
    Mahmoud S Zakherah
    Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Gynecol Obstet Invest 71:281-4. 2011
    ..The pictorial blood assessment chart (PBAC) is a method for evaluation of menstrual blood loss (MBL). This study was conducted to evaluate the accuracy of the PBAC score in diagnosing MBL compared to alkaline hematin as a gold standard...
  64. ncbi Oral contraceptives and DDAVP nasal spray: patterns of use in managing vWD-associated menorrhagia: a single-institution study
    Lawrence S Amesse
    Section of Pediatric Adolescent Gynecology, Division of Reproductive Endocrinology and Infertility, Wright State University School of Medicine, Dayton, Ohio 45409, USA
    J Pediatr Hematol Oncol 27:357-63. 2005
    ..to examine patterns of use for oral contraceptive and desmopressin acetate nasal spray, both used in managing menorrhagia in adolescents with von Willebrand disease (vWD)...
  65. ncbi Menorrhagia in adolescents with inherited bleeding disorders
    Claudia Chi
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    J Pediatr Adolesc Gynecol 23:215-22. 2010
    We reviewed the management and treatment outcomes of menorrhagia in adolescents with inherited bleeding disorders and assessed the impact of menorrhagia on their quality of life.
  66. ncbi von Willebrand disease in women with menorrhagia: a systematic review
    Meena Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    BJOG 111:734-40. 2004
    To determine the prevalence of von Willebrand disease in women presenting with menorrhagia.
  67. ncbi Effect of Iron Therapy on Platelet Function among Iron-Deficient Women with Unexplained Menorrhagia
    Olga Meltem Akay
    Department of Hematology, Eskisehir Osmangazi University Medical School, Eskisehir, Turkey
    Pathophysiol Haemost Thromb 36:80-3. 2008
    ..This study was performed to evaluate the effect of iron therapy on platelet function among women with unexplained menorrhagia in order to better understand possible interactions between iron deficiency anemia and platelet behavior and ..
  68. ncbi Health-related quality of life and patient satisfaction after global endometrial ablation for menorrhagia in women with bleeding disorders: a follow-up survey and systematic review
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Obstet Gynecol 202:348.e1-7. 2010
    ..The purpose of this study was to describe health-related quality of life and satisfaction after global endometrial ablation in women with bleeding disorders and a systematic review of the literature...
  69. ncbi Estimating menstrual blood loss in women with normal and excessive menstrual fluid volume
    I S Fraser
    Sydney Centre for Reproductive Health Research, Family Planning NSW, Sydney, Australia
    Obstet Gynecol 98:806-14. 2001
    ..To examine the relationship between total fluid volume at menstruation and the volume of blood loss, and to assess the feasibility of using total fluid volume to estimate menstrual blood loss...
  70. ncbi A randomized controlled trial of hysterectomy or levonorgestrel-releasing intrauterine system in the treatment of menorrhagia-effect on FSH levels and menopausal symptoms
    K Halmesmäki
    Department of Obstetrics and Gynecology, Central Hospital of Päijät Häme, Keskussairaalankatu 7, 15850 Lahti, Finland
    Hum Reprod 19:378-82. 2004
    ..The purpose of this study was to compare the effects of hysterectomy and a levonorgestrel-releasing intrauterine system (LNG-IUS) on serum FSH levels and menopausal symptoms...
  71. ncbi A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible cause
    Anne Dilley
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, Georgia 30333, USA
    J Womens Health Gend Based Med 11:39-44. 2002
    ..to determine perceptions and practices of American gynecologists when treating with a woman complaining of menorrhagia, specifically with regard to an underlying bleeding disorder as a potential cause...
  72. ncbi Assessment of menorrhagia by total menstrual fluid loss
    P C Reid
    Luton and Dunstable NHS Trust, Luton, UK
    J Obstet Gynaecol 26:438-41. 2006
    Half of the women presenting with heavy periods do not have objective menorrhagia. In the normal woman, blood is a minority component of total menstrual volume...
  73. ncbi Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acid
    Peter A Kouides
    Mary M Gooley Hemophilia Center and the Rochester General Hospital, Rochester, NY 14621, USA
    Br J Haematol 145:212-20. 2009
    The optimal management of menorrhagia among women with abnormal laboratory haemostasis is uncertain...
  74. pmc Referral for menstrual problems: cross sectional survey of symptoms, reasons for referral, and management
    P Warner
    Public Health Sciences, Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG
    BMJ 323:24-8. 2001
    To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's ..
  75. ncbi [Surgical therapeutic management for menorrhagia]
    J P Lucot
    Hopital Jeanne de Flandre, CHU de Lille, pôle de gynécologie, 59037 Lille Cedex, France
    J Gynecol Obstet Biol Reprod (Paris) 37:S398-404. 2008
    ..The possibility of further surgery should however be discussed pre-operatively. In case of hysterectomy, abdominal route is not recommended, and vaginal or laparoscopic routes are preferred...
  76. ncbi Inherited bleeding disorders in Indian women with menorrhagia
    R Saxena
    Department of Haematology, All India Institute of Medical Sciences, New Delhi, India
    Haemophilia 9:193-6. 2003
    In order to define the prevalence of haemostatic defects in women presenting with menorrhagia in our region, the coagulation data on women bleeders investigated in the Department of Haematology, AIIMS, were analysed...
  77. ncbi Medium-term clinical outcome of women with menorrhagia treated by rollerball endometrial ablation versus abdominal hysterectomy with conservation of at least one ovary
    H A Mousa
    Department of Obstetrics and Gynecology, Liverpool Women's Hospital, Liverpool University, Liverpool, United Kingdom
    Acta Obstet Gynecol Scand 80:442-6. 2001
    ..endometrial ablation or abdominal hysterectomy with conservation of at least one ovary for the treatment of menorrhagia. METHOD: Between March 1992 to June 1997, 91 women underwent rollerball endometrial ablation and 78 women had ..
  78. ncbi Expression of angiopoietins 1, 2 and their common receptor tie-2 in relation to the size of endothelial lining gaps and expression of VEGF and VEGF receptors in idiopathic menorrhagia
    Miriam Mints
    Department of Clinical Science, Division of Obstetrics and Gynaecology, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
    Fertil Steril 94:701-7. 2010
    To investigate whether idiopathic menorrhagia (IM) is associated with alterations of the vascular expression of angiopoietin-1, angiopoietin-2, and tie-2 receptor.
  79. ncbi Is balloon ablation as effective as endometrial electroresection in the treatment of menorrhagia?
    M Y Bongers
    Department of Obstetrics and Gynecology, St Joseph Hospital, Veldhoven, The Netherlands
    J Laparoendosc Adv Surg Tech A 10:85-92. 2000
    Hot-fluid balloon therapy is a recently introduced, relatively simple endometrial ablation procedure for menorrhagia. Because it is thought to be safer than other ablation procedures, it would be superior to other types of ablation if it ..
  80. ncbi Evaluation and treatment of menorrhagia in an adolescent population
    Gary N Frishman
    Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown Medical School, Providence, Rhode Island 02905, USA
    J Minim Invasive Gynecol 15:682-8. 2008
    ..Adolescents present with unique issues related to their age, involvement of family members, different differential diagnosis when compared to an older populations, and challenges associated with their evaluation and treatment...
  81. ncbi The levonorgestrel-releasing intrauterine system provides a reliable, long-term treatment option for women with idiopathic menorrhagia
    Jan Endrikat
    Bayer HealthCare, Berlin, Germany
    Arch Gynecol Obstet 285:117-21. 2012
    Idiopathic menorrhagia (IM) is an important clinical challenge. The levonorgestrel-releasing intrauterine system (LNG IUS) provides an effective treatment option as shown by multiple small clinical studies...
  82. ncbi Menorrhagia in general practice--disease or illness
    N O'Flynn
    Lambeth Walk Group Practice, London, UK
    Soc Sci Med 50:651-61. 2000
    b>Menorrhagia is a common presentation in primary care. The gynaecological literature defines menorrhagia, as the loss of 80 ml or more of blood per period and guidelines for treatment are based on this definition...
  83. ncbi Bipolar radiofrequency endometrial ablation compared with hydrothermablation for dysfunctional uterine bleeding: a randomized controlled trial
    Josien P M Penninx
    Department of Obstetrics and Gynecology, Maxima Medical Centre, Veldhoven, The Netherlands
    Obstet Gynecol 116:819-26. 2010
    To compare the effectiveness of two second-generation ablation techniques, bipolar radiofrequency impedance-controlled endometrial ablation and hydrothermablation, in the treatment of menorrhagia.
  84. ncbi Randomised controlled trial of bipolar radio-frequency endometrial ablation and balloon endometrial ablation
    Marlies Y Bongers
    Department of Obstetrics and Gynaecology, Maxima Medical Centre, Veldhoven, The Netherlands
    BJOG 111:1095-102. 2004
    To compare the effectiveness of two second-generation ablation techniques, bipolar radio-frequency impedance-controlled endometrial ablation (NovaSure) and balloon ablation (ThermaChoice), in the treatment of menorrhagia.
  85. ncbi Hematological abnormalities in adolescent menorrhagia
    E Oral
    Department of Obstetrics and Gynecology, Cerrahpasa Medical School, Istanbul University, Turkey
    Arch Gynecol Obstet 266:72-4. 2002
    The purpose of this study is to determine the frequency of underlying hematological disorders as the cause of acute adolescent menorrhagia.
  86. ncbi Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia
    B Chattopdhyay
    Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India
    Eur Rev Med Pharmacol Sci 15:764-8. 2011
    To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia.
  87. ncbi The effect of levonorgestrel-releasing intrauterine system use on menstrual blood loss and the hemostatic, fibrinolytic/inhibitor systems in women with menorrhagia
    S C L Koh
    Department of Obstetrics and Gynaecology, National University of Singapore, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Singapore
    J Thromb Haemost 5:133-8. 2007
    b>Menorrhagia is known to be associated with uterine fibroids, adenomyosis, pelvic infections, endometrial polyps and clotting defects...
  88. ncbi Microwave endometrial ablation for menorrhagia: outcome at 2 years--experience of a district general hospital
    B Sharma
    Department of Obstetrics and Gynaecology, James Paget Hospital, Great Yarmouth, UK
    J Obstet Gynaecol 24:916-9. 2004
    ..There were a few minor complications but no uterine perforation or emergency hysterectomies in the group studied...
  89. ncbi Review of quality of life: menorrhagia in women with or without inherited bleeding disorders
    M Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    Haemophilia 14:15-20. 2008
    The objectives of this study were to identify the impact of menorrhagia on the health-related quality of life (HRQOL) of women in general and those with inherited bleeding disorders and to identify the commonly used tools in assessing ..
  90. ncbi Menorrhagia: an update
    M K Oehler
    Department of Obstetrics and Gynecology, Westmead Hospital, University of Sydney, Westmead, NSW, Australia
    Acta Obstet Gynecol Scand 82:405-22. 2003
    b>Menorrhagia is defined as a 'complaint of heavy cyclical menstrual bleeding occurring over several consecutive cycles'. Objectively it is a total menstrual blood loss equal to or greater than 80 ml per menstruation...
  91. ncbi Modern management of menorrhagia
    Joanne Protheroe
    National Primary Care Research and Development Centre, University of Manchester, Manchester, UK
    J Fam Plann Reprod Health Care 30:118-22. 2004
    b>Menorrhagia, defined clinically as menstrual blood loss in excess of 80 ml per cycle, is a common gynaecological complaint that presents both to primary and secondary care...
  92. ncbi Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate
    Dror Meirow
    Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Cancer 107:1634-41. 2006
    b>Menorrhagia is a serious complication in young female oncology patients who suffer from severe thrombocytopenia during myelosuppressive treatment...
  93. ncbi A randomized clinical trial of a levonorgestrel-releasing intrauterine system and a low-dose combined oral contraceptive for fibroid-related menorrhagia
    Gamal H Sayed
    Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Int J Gynaecol Obstet 112:126-30. 2011
    To compare the efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS) with that of a low-dose combined oral contraceptive (COC) in reducing fibroid-related menorrhagia.
  94. ncbi Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a significant regression in the uterine and leiomyoma volumes
    Mehmet Murat Naki
    Obstetrics and Gynecology Department, Dr Lutfi Kirdar Kartal Research and Training Hospital, Kartal, Istanbul, Turkey
    Fertil Steril 94:371-4. 2010
    ..LNG-IUD can be considered as a simple and effective alternative to surgical treatment in the management of leiomyoma-dependent menorrhagia of reproductive-age women.
  95. ncbi Surgery for menorrhagia within English regions: variation in rates of endometrial ablation and hysterectomy
    D A Cromwell
    Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, UK
    BJOG 116:1373-9. 2009
    To examine variation between English regions in the use of surgery (endometrial ablation or hysterectomy) for the treatment of menorrhagia.
  96. pmc Down-regulation of angiopoietin-1 expression in menorrhagia
    Peter Hewett
    Department of Reproductive and Vascular Biology, TheMedical School, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Am J Pathol 160:773-80. 2002
    ..Perturbation of this process is associated with menorrhagia, a common gynecological disorder that results in excessive menstrual bleeding...
  97. ncbi Treatment of menorrhagia with the levonorgestrel intrauterine system versus endometrial resection
    O Istre
    Department of Obstetrics and Gynecology, Central Hospital of Hedmark County, Hamar, Norway
    Fertil Steril 76:304-9. 2001
    Treatment of menorrhagia with levonorgestrel intrauterine system (LNG IUS) and transcervical resection.
  98. ncbi Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study
    Yun Hwan Kim
    Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea
    Acta Haematol 121:37-41. 2009
    ..safety and achievement of the target hemoglobin level (Hb >or=10 g/dl) in patients with preoperative anemia due to menorrhagia who received intravenous iron sucrose compared with oral iron protein succinylate for anemia management.
  99. ncbi Outpatient microwave endometrial ablation: 5-year follow-up of a randomised controlled trial without endometrial preparation versus standard day surgery with endometrial preparation
    A M Sambrook
    Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    BJOG 117:493-6. 2010
    ..It can be concluded that microwave endometrial ablation outcomes are not affected in the long term by undertaking the procedure in the postmenstrual phase in an outpatient setting...
  100. ncbi Perioperative complication rates of primary and repeat hysteroscopic endometrial ablations
    Erin MacLean-Fraser
    Department of Obstetrics and Gynaecology, St Joseph s Health Care, 268 Grosvenor St, London, Ontario N6A 4V2, Canada
    J Am Assoc Gynecol Laparosc 9:175-7. 2002
    ..To determine perioperative complication rates at primary and repeat endometrial ablations...
  101. ncbi Migraine is associated with menorrhagia and endometriosis
    Gretchen E Tietjen
    Department of Neurology, Medical College of Ohio, Toledo 43614, USA
    Headache 46:422-8. 2006
    To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched women without headache.

Research Grants19

  1. Prevention of the Complications of Hemophilia Thru Hemophilila Treatment Centers
    MD WALSH; Fiscal Year: 2010
    ..Some aims will be directly transferable to other chronic disease populations in the general public such as the evaluation of obesity and menorrhagia.
  2. Feasibility of the Von Willebrand Disease Minimize Trial
    MARGARET VICTORIA RAGNI; Fiscal Year: 2013
    ..interleukin-11 (rhIL-11) with tranexamic acid (TA), the current recommended non-hormonal treatment, to reduce menorrhagia in women with type 1 von Willebrand disease (VWD)...
  3. Extra / Intra-cellular Signaling in Novel 3-Dimensional Human Leiomyoma Cultures
    WILLIAM HENRY CATHERINO; Fiscal Year: 2013
    ..provided by applicant): Uterine leiomyoma play a significant role in miscarriage, infertility, preterm labor, menorrhagia, pelvic pain, and urinary incontinence...
  4. Zimmerman Program for the Molecular and Clinical Biology of VWD
    Robert R Montgomery; Fiscal Year: 2013
    ..Some newer pilot studies will also study the impact of VWD on clinical menorrhagia and Quality of Life studies in VWD patients...
  5. SURGICAL TREATMENTS OUTCOMES PROJECT FOR DUB (STOP-DUB)
    Kay Dickersin; Fiscal Year: 2000
    ..Estimates of prevalence for menorrhagia range from 9-20% of women, and metrorrhagia occurs in 53 women per 1,000...
  6. CENTER FOR ALTERNATIVE MEDICINE IN WOMENS HEALTH
    Fredi Kronenberg; Fiscal Year: 1999
    ..on 4 problems that affect a large number of women, namely, menopausal hot flashes, fibroids, dysmenorrhea and menorrhagia. The center will identify practitioners in the following 4 program areas who are interested in evaluating their ..
  7. PDE3 Inhibitors: Selective Blockers of Oocyte Maturation
    Jeffrey Jensen; Fiscal Year: 2007
    ..This approach is expected to provide a foundation for future Phase 1 trials of PDE3 inhibitors in humans. ..
  8. Control of menstrual bleeding disturbances in women
    Ian Fraser; Fiscal Year: 2006
    ..This study aims to explore these possibilities in large scale clinical studies, scientific study of vascular and molecular changes in endometrium and with the exploration of molecular mechanisms in mice. ..
  9. DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORS
    David Archer; Fiscal Year: 2006
    ..If successful, DOX treatment could become an important adjuvant for treatment of this and possibly other inflammatory disorders effecting reproductive tract tissues. ..
  10. CAREER DEVELOPMENT IN WOMEN'S HEALTH RESEARCH AND GENDE*
    Ellen Freeman; Fiscal Year: 2006
    ..The BIRCWH program will track the career trajectories of Scholars and will continue to serve as a resource in terms of career counseling and research advice. [unreadable] [unreadable]..
  11. Core symptoms and profiles in premenstrual syndrome
    Ellen Freeman; Fiscal Year: 2008
    ..Further information will contribute to improved health care for women in their reproductive years. [unreadable] [unreadable] [unreadable] [unreadable]..
  12. CARDIOPROTECTIVE EFFECT--NEW CHELATORS FOR THALASSEMIA
    Chaim Hershko; Fiscal Year: 2001
    ..abstract_text> ..
  13. Obstacles to Answering Physicians' Patient-Care Question
    John Ely; Fiscal Year: 2003
    ..Benefit: By identifying areas where knowledge resources fail to meet the needs of physicians, we will provide recommendations to help knowledge base developers better meet those needs. ..
  14. Prophylactic Ibuprofen: Effect on IUD Continuation Rates
    David Hubacher; Fiscal Year: 2003
    ..In the US, ibuprofen may help spur renewed interest in the most cost effective and efficacious reversible contraceptive method available. ..
  15. Menopause Depression and Aging
    Joyce T Bromberger; Fiscal Year: 2010
    ..Increasing knowledge of the risks for depression in aging women and the factors that protect them from depression can identify targets for intervention at the prevention as well as the acute treatment level. ..
  16. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen W Freeman; Fiscal Year: 2010
    ..abstract_text> ..
  17. A Genome-Wide Association Study of Non-Hodgkin Lymphoma
    Christine F Skibola; Fiscal Year: 2010
    ..The data generated from this study will provide a framework for further investigation within the NHL consortium, InterLymph. Results will later be combined with that from other InterLymph case-control studies in pooled analyses. ..
  18. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2008
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  19. HOX GENE EXPRESSION IN HUMAN ENDOMETRIUM
    Hugh Taylor; Fiscal Year: 2007
    ..These studies will further characterize the molecular mechanisms by which HOX expression is related to normal and pathologic endometrial development. ..