menorrhagia

Summary

Summary: Excessive uterine bleeding during MENSTRUATION.

Top Publications

  1. ncbi Treatment of menorrhagia
    Barbara S Apgar
    University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Am Fam Physician 75:1813-9. 2007
  2. doi Effective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind Phase III trial
    I S Fraser
    Department of Obstetrics and Gynaecology, Central Clinical School, D02 QEII Research Institute for Mothers and Infants, University of Sydney, Sydney, NSW 2006, Australia
    Hum Reprod 26:2698-708. 2011
  3. ncbi A Scottish postal survey suggested that the prevailing clinical preoccupation with heavy periods does not reflect the epidemiology of reported symptoms and problems
    Miriam Santer
    Tayside Centre for General Practice, Mackenzie Building, Dundee, UK
    J Clin Epidemiol 58:1206-10. 2005
  4. doi Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial
    Jeffrey T Jensen
    Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
    Obstet Gynecol 117:777-87. 2011
  5. ncbi Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagia
    A Kriplani
    Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
    Int J Gynaecol Obstet 97:190-4. 2007
  6. ncbi Menorrhagia due to abnormalities of the platelet function: evaluation of two young patients
    Yesim Aydinok
    Division of Pediatric Hematology, Department of Pediatrics, School of Medicine, Ege University, Izmir, Turkey
    Pediatr Int 49:106-8. 2007
  7. ncbi Bleeding disorders: A common cause of menorrhagia in adolescents
    J A Bevan
    Department of Pediatrics, Section of Pediatric Hematology and Oncology, Medical College and Children's Hospital of Wisconsin, Milwaukee, WI 53201-2178, USA
    J Pediatr 138:856-61. 2001
  8. pmc Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients
    L J Middleton
    Birmingham Clinical Trials Unit, University of Birmingham, Birmingham B15 2TT
    BMJ 341:c3929. 2010
  9. ncbi Work loss associated with increased menstrual loss in the United States
    Isabelle Côté
    Institute of Health Economics, Edmonton, Alberta, Canada
    Obstet Gynecol 100:683-7. 2002
  10. doi Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: a randomized controlled trial
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA
    Obstet Gynecol 116:625-32. 2010

Research Grants

  1. Estrogen Dependency of Uterine Leiomyoma
    Ayman Al Hendy; Fiscal Year: 2007
  2. Molecular and Clinical Biology of VWD
    Robert Montgomery; Fiscal Year: 2007
  3. Control of menstrual bleeding disturbances in women
    Ian Fraser; Fiscal Year: 2006
  4. PDE3 Inhibitors: Selective Blockers of Oocyte Maturation
    Jeffrey Jensen; Fiscal Year: 2007
  5. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1992
  6. Menopause Depression and Aging
    Joyce T Bromberger; Fiscal Year: 2010
  7. DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORS
    David Archer; Fiscal Year: 2006
  8. Short-Term vs Long-Term Treatment for Servere PMS
    Ellen Freeman; Fiscal Year: 2006
  9. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1993
  10. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 2001

Detail Information

Publications272 found, 100 shown here

  1. ncbi Treatment of menorrhagia
    Barbara S Apgar
    University of Michigan Medical Center, Ann Arbor, Michigan, USA
    Am Fam Physician 75:1813-9. 2007
    b>Menorrhagia is defined as excessive uterine bleeding occurring at regular intervals or prolonged uterine bleeding lasting more than seven days. The classic definition of menorrhagia (i.e...
  2. doi Effective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind Phase III trial
    I S Fraser
    Department of Obstetrics and Gynaecology, Central Clinical School, D02 QEII Research Institute for Mothers and Infants, University of Sydney, Sydney, NSW 2006, Australia
    Hum Reprod 26:2698-708. 2011
    ..This double-blind trial investigated the efficacy and safety of estradiol valerate/dienogest (E(2)V/DNG) for the treatment of heavy menstrual bleeding without recognizable organic pathology...
  3. ncbi A Scottish postal survey suggested that the prevailing clinical preoccupation with heavy periods does not reflect the epidemiology of reported symptoms and problems
    Miriam Santer
    Tayside Centre for General Practice, Mackenzie Building, Dundee, UK
    J Clin Epidemiol 58:1206-10. 2005
    ..To determine the prevalence of self-reported menstrual symptoms and problem periods and explore their relationship with sociodemographic factors, parity, long-standing illness, and hormonal contraceptive use...
  4. doi Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trial
    Jeffrey T Jensen
    Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
    Obstet Gynecol 117:777-87. 2011
    ....
  5. ncbi Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagia
    A Kriplani
    Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
    Int J Gynaecol Obstet 97:190-4. 2007
    To evaluate the efficacy, acceptability, and possible side effects of a levonorgestrel-releasing intrauterine system for menorrhagia.
  6. ncbi Menorrhagia due to abnormalities of the platelet function: evaluation of two young patients
    Yesim Aydinok
    Division of Pediatric Hematology, Department of Pediatrics, School of Medicine, Ege University, Izmir, Turkey
    Pediatr Int 49:106-8. 2007
  7. ncbi Bleeding disorders: A common cause of menorrhagia in adolescents
    J A Bevan
    Department of Pediatrics, Section of Pediatric Hematology and Oncology, Medical College and Children's Hospital of Wisconsin, Milwaukee, WI 53201-2178, USA
    J Pediatr 138:856-61. 2001
    OBJECTIVE: To determine the frequency of underlying bleeding disorders in adolescents with menorrhagia. STUDY DESIGN: We retrospectively reviewed the charts of all girls, aged 10 to 19 years, who presented to our children's hospital for ..
  8. pmc Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patients
    L J Middleton
    Birmingham Clinical Trials Unit, University of Birmingham, Birmingham B15 2TT
    BMJ 341:c3929. 2010
    ....
  9. ncbi Work loss associated with increased menstrual loss in the United States
    Isabelle Côté
    Institute of Health Economics, Edmonton, Alberta, Canada
    Obstet Gynecol 100:683-7. 2002
    ..To estimate the effect of increased menstrual flow on the loss of work...
  10. doi Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: a randomized controlled trial
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA
    Obstet Gynecol 116:625-32. 2010
    ..To compare the efficacy and safety of the levonorgestrel-releasing intrauterine system and oral medroxyprogesterone acetate in the treatment of idiopathic heavy menstrual bleeding...
  11. ncbi Platelet functional defects in women with unexplained menorrhagia
    C S Philipp
    Division of Hematology and Women s Health Institute, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
    J Thromb Haemost 1:477-84. 2003
    b>Menorrhagia is a common clinical problem and is unexplained in more than 50% of women...
  12. pmc Why women consult with increased vaginal bleeding: a case-control study
    Mark Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire
    Br J Gen Pract 52:108-13. 2002
    ....
  13. ncbi The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centre
    S Mikhail
    Department of Medicine, Rochester General Hospital, 1415 Portland Avenue, Rochester, NY 14621, USA
    Haemophilia 13:627-32. 2007
    b>Menorrhagia at the time of menarche is relatively common and historically attributed primarily to immaturity of the pituitary-ovarian-uterine axis...
  14. ncbi Adolescent menorrhagia due to platelet function disorder
    Nazli Hossain
    Department of Obstetrics and Gynecology Unit 3, Dow University of Health Sciences and Civil Hospital Karachi
    J Pak Med Assoc 60:127-9. 2010
    The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%...
  15. ncbi Bleeding disorders in teenagers presenting with menorrhagia
    Yasmin Jayasinghe
    Department of Paediatric and Adolescent Gynaecology, Royal Children s Hospital, Melbourne, Australia
    Aust N Z J Obstet Gynaecol 45:439-43. 2005
    ..To assess the prevalence of bleeding disorders and establish the clinical variables that are predictive of a bleeding disorder in adolescent women...
  16. ncbi Migraine is associated with menorrhagia and endometriosis
    Gretchen E Tietjen
    Department of Neurology, Medical College of Ohio, Toledo 43614, USA
    Headache 46:422-8. 2006
    To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched women without headache.
  17. doi Factor VII Deficiency
    Guglielmo Mariani
    Dipartimento di Medicina Interna e Sanita Pubblica, Universita dell Aquila, L Aquila 67010, Italy
    Semin Thromb Hemost 35:400-6. 2009
    ..In females, menorrhagia is prevalent and affects two thirds of the patients of fertile age...
  18. pmc An epidemiological survey of symptoms of menstrual loss in the community
    Mark Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire
    Br J Gen Pract 54:359-63. 2004
    ..The evidence for this advice is based on the prevalence of symptoms in women with gynaecological malignancy or within specialist clinics. There are no studies on the incidence of symptoms within the community...
  19. doi Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trial
    Andrea S Lukes
    Carolina Women s Research and Wellness Center, Durham, North Carolina 27713, USA
    Obstet Gynecol 116:865-75. 2010
    ..To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding...
  20. ncbi Determination of total menstrual blood loss
    K M Wyatt
    Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital, Stoke-on-Trent, United Kingdom
    Fertil Steril 76:125-31. 2001
    ..SETTING: Academic menorrhagia research clinic...
  21. ncbi von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagia
    A Dilley
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, GA, USA
    Obstet Gynecol 97:630-6. 2001
    To estimate the prevalence of von Willebrand disease and other bleeding disorders in women with and without diagnosed menorrhagia.
  22. doi Levonorgestrel intrauterine system versus medical therapy for menorrhagia
    Janesh Gupta
    School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom
    N Engl J Med 368:128-37. 2013
    b>Menorrhagia is a common problem, yet evidence to inform decisions about therapy is limited...
  23. pmc Heavy menstrual bleeding: delivering patient-centred care
    Miriam Santer
    Br J Gen Pract 58:151-2. 2008
  24. ncbi Tranexamic acid: a review of its use in the management of menorrhagia
    Keri Wellington
    Adis International Limited, Auckland, New Zealand
    Drugs 63:1417-33. 2003
    ..In a number of small clinical studies in women with idiopathic menorrhagia, tranexamic acid 2-4...
  25. ncbi Levonorgestrel-releasing intrauterine system vs. endometrial thermal ablation for menorrhagia
    Theodoros D Theodoridis
    1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Periferiaki Odos Thessalonikis, N Efkarpia, Thessaloniki, Greece
    Hormones (Athens) 8:60-4. 2009
    To evaluate the efficacy of a Levonorgestrel-releasing Intrauterine System (LNG-IUS) in controlling menorrhagia in comparison with endometrial thermal rollerball ablation.
  26. doi A cost-utility analysis of microwave endometrial ablation versus thermal balloon endometrial ablation
    Mary M Kilonzo
    Health Economics Research Unit, University of Aberdeen, UK
    Value Health 13:528-34. 2010
    ..To evaluate the cost-effectiveness of microwave endometrial ablation (MEA) and thermal balloon endometrial ablation (TBALL) for heavy menstrual bleeding...
  27. pmc Efficacy of bipolar radiofrequency endometrial ablation vs thermal balloon ablation for management of menorrhagia: A population-based cohort
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Minim Invasive Gynecol 16:692-9. 2009
    ..To compare the efficacy of bipolar radiofrequency ablation (RFA) and thermal balloon ablation (TBA) using treatment failure and postprocedure amenorrhea as outcome measures...
  28. doi Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleeding
    A M Sambrook
    Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Aberdeen, UK
    BJOG 116:1038-45. 2009
    ..To compare the clinical outcomes of microwave endometrial ablation and thermal balloon ablation for the treatment of heavy menstrual bleeding...
  29. ncbi A randomised controlled trial comparing the Cavaterm endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleeding
    Jed Hawe
    Department of Obstetrics and Gynaecology, Countess of Chester Hospital, UK
    BJOG 110:350-7. 2003
    ..To compare the effectiveness of the Cavaterm thermal balloon endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleeding...
  30. ncbi Screening women with menorrhagia for underlying bleeding disorders: the utility of the platelet function analyser and bleeding time
    C S Philipp
    Division of Hematology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
    Haemophilia 11:497-503. 2005
    b>Menorrhagia is a very common clinical problem among women of reproductive age and recent studies have suggested that underlying bleeding disorders, particularly von Willebrand's deficiency and platelet function defects, are prevalent in ..
  31. ncbi Oral contraceptives and DDAVP nasal spray: patterns of use in managing vWD-associated menorrhagia: a single-institution study
    Lawrence S Amesse
    Section of Pediatric Adolescent Gynecology, Division of Reproductive Endocrinology and Infertility, Wright State University School of Medicine, Dayton, Ohio 45409, USA
    J Pediatr Hematol Oncol 27:357-63. 2005
    ..to examine patterns of use for oral contraceptive and desmopressin acetate nasal spray, both used in managing menorrhagia in adolescents with von Willebrand disease (vWD)...
  32. ncbi Estimating menstrual blood loss in women with normal and excessive menstrual fluid volume
    I S Fraser
    Sydney Centre for Reproductive Health Research, Family Planning NSW, Sydney, Australia
    Obstet Gynecol 98:806-14. 2001
    ..To examine the relationship between total fluid volume at menstruation and the volume of blood loss, and to assess the feasibility of using total fluid volume to estimate menstrual blood loss...
  33. doi Effect of Iron Therapy on Platelet Function among Iron-Deficient Women with Unexplained Menorrhagia
    Olga Meltem Akay
    Department of Hematology, Eskisehir Osmangazi University Medical School, Eskisehir, Turkey
    Pathophysiol Haemost Thromb 36:80-3. 2008
    ..This study was performed to evaluate the effect of iron therapy on platelet function among women with unexplained menorrhagia in order to better understand possible interactions between iron deficiency anemia and platelet behavior and ..
  34. doi Pictorial blood loss assessment chart in the evaluation of heavy menstrual bleeding: diagnostic accuracy compared to alkaline hematin
    Mahmoud S Zakherah
    Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Gynecol Obstet Invest 71:281-4. 2011
    ..The pictorial blood assessment chart (PBAC) is a method for evaluation of menstrual blood loss (MBL). This study was conducted to evaluate the accuracy of the PBAC score in diagnosing MBL compared to alkaline hematin as a gold standard...
  35. doi Menorrhagia in adolescents with inherited bleeding disorders
    Claudia Chi
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    J Pediatr Adolesc Gynecol 23:215-22. 2010
    We reviewed the management and treatment outcomes of menorrhagia in adolescents with inherited bleeding disorders and assessed the impact of menorrhagia on their quality of life.
  36. ncbi Increased vaginal bleeding: the reasons women give for consulting primary care
    M Shapley
    Primary Care Sciences Research Centre, Keele University, Staffordshire, UK
    J Obstet Gynaecol 23:48-50. 2003
    ..This does not distinguish consulters and non-consulters and is not reflected in objective measures of psychological distress. Clinicians should focus initially on treating the presenting physical symptoms...
  37. ncbi von Willebrand disease in women with menorrhagia: a systematic review
    Meena Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    BJOG 111:734-40. 2004
    To determine the prevalence of von Willebrand disease in women presenting with menorrhagia.
  38. ncbi Diagnosis and treatment of menorrhagia
    R Hurskainen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    Acta Obstet Gynecol Scand 86:749-57. 2007
    ..In western countries, about 5% of women of reproductive age will seek help for menorrhagia annually...
  39. doi The levonorgestrel-releasing intrauterine system in heavy menstrual bleeding: a benefit-risk review
    Andrew M Kaunitz
    Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, FL 32209, USA
    Drugs 72:193-215. 2012
    ..In conclusion, the LNG-IUS is an effective treatment option for women with HMB, including those with underlying organic pathology or bleeding disorders...
  40. ncbi Age and the prevalence of bleeding disorders in women with menorrhagia
    Claire S Philipp
    Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    Obstet Gynecol 105:61-6. 2005
    A study was conducted to evaluate the frequency and types of hemostatic defects occurring in adolescent and perimenopausal-age women diagnosed with menorrhagia.
  41. doi Health-related quality of life and patient satisfaction after global endometrial ablation for menorrhagia in women with bleeding disorders: a follow-up survey and systematic review
    Sherif A El-Nashar
    Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Obstet Gynecol 202:348.e1-7. 2010
    ..The purpose of this study was to describe health-related quality of life and satisfaction after global endometrial ablation in women with bleeding disorders and a systematic review of the literature...
  42. ncbi Assessment of menorrhagia by total menstrual fluid loss
    P C Reid
    Luton and Dunstable NHS Trust, Luton, UK
    J Obstet Gynaecol 26:438-41. 2006
    Half of the women presenting with heavy periods do not have objective menorrhagia. In the normal woman, blood is a minority component of total menstrual volume...
  43. ncbi A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible cause
    Anne Dilley
    Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, Georgia 30333, USA
    J Womens Health Gend Based Med 11:39-44. 2002
    ..to determine perceptions and practices of American gynecologists when treating with a woman complaining of menorrhagia, specifically with regard to an underlying bleeding disorder as a potential cause...
  44. doi Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acid
    Peter A Kouides
    Mary M Gooley Hemophilia Center and the Rochester General Hospital, Rochester, NY 14621, USA
    Br J Haematol 145:212-20. 2009
    The optimal management of menorrhagia among women with abnormal laboratory haemostasis is uncertain...
  45. ncbi A randomized controlled trial of hysterectomy or levonorgestrel-releasing intrauterine system in the treatment of menorrhagia-effect on FSH levels and menopausal symptoms
    K Halmesmäki
    Department of Obstetrics and Gynecology, Central Hospital of Päijät Häme, Keskussairaalankatu 7, 15850 Lahti, Finland
    Hum Reprod 19:378-82. 2004
    ..The purpose of this study was to compare the effects of hysterectomy and a levonorgestrel-releasing intrauterine system (LNG-IUS) on serum FSH levels and menopausal symptoms...
  46. ncbi Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resection
    Ilkka Rauramo
    The Finnish Medical Society Duodecim, Helsinki, Finland
    Obstet Gynecol 104:1314-21. 2004
    The purpose of this study was to compare the long-term efficacy of the levonorgestrel intrauterine system and transcervical resection of the endometrium in the treatment of menorrhagia.
  47. pmc Referral for menstrual problems: cross sectional survey of symptoms, reasons for referral, and management
    P Warner
    Public Health Sciences, Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG
    BMJ 323:24-8. 2001
    To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's ..
  48. doi Evaluation and treatment of menorrhagia in an adolescent population
    Gary N Frishman
    Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown Medical School, Providence, Rhode Island 02905, USA
    J Minim Invasive Gynecol 15:682-8. 2008
    ..Adolescents present with unique issues related to their age, involvement of family members, different differential diagnosis when compared to an older populations, and challenges associated with their evaluation and treatment...
  49. doi Bipolar radiofrequency endometrial ablation compared with hydrothermablation for dysfunctional uterine bleeding: a randomized controlled trial
    Josien P M Penninx
    Department of Obstetrics and Gynecology, Maxima Medical Centre, Veldhoven, The Netherlands
    Obstet Gynecol 116:819-26. 2010
    To compare the effectiveness of two second-generation ablation techniques, bipolar radiofrequency impedance-controlled endometrial ablation and hydrothermablation, in the treatment of menorrhagia.
  50. doi [Surgical therapeutic management for menorrhagia]
    J P Lucot
    Hopital Jeanne de Flandre, CHU de Lille, pôle de gynécologie, 59037 Lille Cedex, France
    J Gynecol Obstet Biol Reprod (Paris) 37:S398-404. 2008
    ..The possibility of further surgery should however be discussed pre-operatively. In case of hysterectomy, abdominal route is not recommended, and vaginal or laparoscopic routes are preferred...
  51. pmc Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysis
    J P Daniels
    University of Birmingham, Clinical Trials Unit, Birmingham B15 2TT, UK
    BMJ 344:e2564. 2012
    ..To determine the relative effectiveness of second generation ablation techniques in the treatment of heavy menstrual bleeding...
  52. ncbi Randomised controlled trial of bipolar radio-frequency endometrial ablation and balloon endometrial ablation
    Marlies Y Bongers
    Department of Obstetrics and Gynaecology, Maxima Medical Centre, Veldhoven, The Netherlands
    BJOG 111:1095-102. 2004
    To compare the effectiveness of two second-generation ablation techniques, bipolar radio-frequency impedance-controlled endometrial ablation (NovaSure) and balloon ablation (ThermaChoice), in the treatment of menorrhagia.
  53. ncbi Is balloon ablation as effective as endometrial electroresection in the treatment of menorrhagia?
    M Y Bongers
    Department of Obstetrics and Gynecology, St Joseph Hospital, Veldhoven, The Netherlands
    J Laparoendosc Adv Surg Tech A 10:85-92. 2000
    Hot-fluid balloon therapy is a recently introduced, relatively simple endometrial ablation procedure for menorrhagia. Because it is thought to be safer than other ablation procedures, it would be superior to other types of ablation if it ..
  54. ncbi Inherited bleeding disorders in Indian women with menorrhagia
    R Saxena
    Department of Haematology, All India Institute of Medical Sciences, New Delhi, India
    Haemophilia 9:193-6. 2003
    In order to define the prevalence of haemostatic defects in women presenting with menorrhagia in our region, the coagulation data on women bleeders investigated in the Department of Haematology, AIIMS, were analysed...
  55. ncbi Medium-term clinical outcome of women with menorrhagia treated by rollerball endometrial ablation versus abdominal hysterectomy with conservation of at least one ovary
    H A Mousa
    Department of Obstetrics and Gynecology, Liverpool Women's Hospital, Liverpool University, Liverpool, United Kingdom
    Acta Obstet Gynecol Scand 80:442-6. 2001
    ..endometrial ablation or abdominal hysterectomy with conservation of at least one ovary for the treatment of menorrhagia. METHOD: Between March 1992 to June 1997, 91 women underwent rollerball endometrial ablation and 78 women had ..
  56. ncbi Menorrhagia in general practice--disease or illness
    N O'Flynn
    Lambeth Walk Group Practice, London, UK
    Soc Sci Med 50:651-61. 2000
    b>Menorrhagia is a common presentation in primary care. The gynaecological literature defines menorrhagia, as the loss of 80 ml or more of blood per period and guidelines for treatment are based on this definition...
  57. doi The levonorgestrel-releasing intrauterine system provides a reliable, long-term treatment option for women with idiopathic menorrhagia
    Jan Endrikat
    Bayer HealthCare, Berlin, Germany
    Arch Gynecol Obstet 285:117-21. 2012
    Idiopathic menorrhagia (IM) is an important clinical challenge. The levonorgestrel-releasing intrauterine system (LNG IUS) provides an effective treatment option as shown by multiple small clinical studies...
  58. doi Expression of angiopoietins 1, 2 and their common receptor tie-2 in relation to the size of endothelial lining gaps and expression of VEGF and VEGF receptors in idiopathic menorrhagia
    Miriam Mints
    Department of Clinical Science, Division of Obstetrics and Gynaecology, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
    Fertil Steril 94:701-7. 2010
    To investigate whether idiopathic menorrhagia (IM) is associated with alterations of the vascular expression of angiopoietin-1, angiopoietin-2, and tie-2 receptor.
  59. ncbi The effect of levonorgestrel-releasing intrauterine system use on menstrual blood loss and the hemostatic, fibrinolytic/inhibitor systems in women with menorrhagia
    S C L Koh
    Department of Obstetrics and Gynaecology, National University of Singapore, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Singapore
    J Thromb Haemost 5:133-8. 2007
    b>Menorrhagia is known to be associated with uterine fibroids, adenomyosis, pelvic infections, endometrial polyps and clotting defects...
  60. ncbi Hematological abnormalities in adolescent menorrhagia
    E Oral
    Department of Obstetrics and Gynecology, Cerrahpasa Medical School, Istanbul University, Turkey
    Arch Gynecol Obstet 266:72-4. 2002
    The purpose of this study is to determine the frequency of underlying hematological disorders as the cause of acute adolescent menorrhagia.
  61. ncbi Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagia
    B Chattopdhyay
    Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India
    Eur Rev Med Pharmacol Sci 15:764-8. 2011
    To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia.
  62. ncbi Microwave endometrial ablation for menorrhagia: outcome at 2 years--experience of a district general hospital
    B Sharma
    Department of Obstetrics and Gynaecology, James Paget Hospital, Great Yarmouth, UK
    J Obstet Gynaecol 24:916-9. 2004
    ..There were a few minor complications but no uterine perforation or emergency hysterectomies in the group studied...
  63. ncbi Review of quality of life: menorrhagia in women with or without inherited bleeding disorders
    M Shankar
    Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
    Haemophilia 14:15-20. 2008
    The objectives of this study were to identify the impact of menorrhagia on the health-related quality of life (HRQOL) of women in general and those with inherited bleeding disorders and to identify the commonly used tools in assessing ..
  64. doi Surgery for menorrhagia within English regions: variation in rates of endometrial ablation and hysterectomy
    D A Cromwell
    Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, UK
    BJOG 116:1373-9. 2009
    To examine variation between English regions in the use of surgery (endometrial ablation or hysterectomy) for the treatment of menorrhagia.
  65. doi Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a significant regression in the uterine and leiomyoma volumes
    Mehmet Murat Naki
    Obstetrics and Gynecology Department, Dr Lutfi Kirdar Kartal Research and Training Hospital, Kartal, Istanbul, Turkey
    Fertil Steril 94:371-4. 2010
    ..LNG-IUD can be considered as a simple and effective alternative to surgical treatment in the management of leiomyoma-dependent menorrhagia of reproductive-age women.
  66. doi A randomized clinical trial of a levonorgestrel-releasing intrauterine system and a low-dose combined oral contraceptive for fibroid-related menorrhagia
    Gamal H Sayed
    Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
    Int J Gynaecol Obstet 112:126-30. 2011
    To compare the efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS) with that of a low-dose combined oral contraceptive (COC) in reducing fibroid-related menorrhagia.
  67. doi Outpatient microwave endometrial ablation: 5-year follow-up of a randomised controlled trial without endometrial preparation versus standard day surgery with endometrial preparation
    A M Sambrook
    Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
    BJOG 117:493-6. 2010
    ..It can be concluded that microwave endometrial ablation outcomes are not affected in the long term by undertaking the procedure in the postmenstrual phase in an outpatient setting...
  68. ncbi Treatment of menorrhagia with the levonorgestrel intrauterine system versus endometrial resection
    O Istre
    Department of Obstetrics and Gynecology, Central Hospital of Hedmark County, Hamar, Norway
    Fertil Steril 76:304-9. 2001
    Treatment of menorrhagia with levonorgestrel intrauterine system (LNG IUS) and transcervical resection.
  69. doi Levonorgestrel-releasing intrauterine system compared to low dose combined oral contraceptive pills for idiopathic menorrhagia: a randomized clinical trial
    Mamdouh M Shaaban
    Faculty of Medicine, Department of Obstetrics and Gynecology, Assiut University, Assiut 71526, Egypt
    Contraception 83:48-54. 2011
    This study compared the efficacy of the levonorgestrel-releasing intrauterine system (LNG-IUS) to low dose combined oral contraceptive pills (COC) in the management of idiopathic menorrhagia.
  70. ncbi Menorrhagia: an update
    M K Oehler
    Department of Obstetrics and Gynecology, Westmead Hospital, University of Sydney, Westmead, NSW, Australia
    Acta Obstet Gynecol Scand 82:405-22. 2003
    b>Menorrhagia is defined as a 'complaint of heavy cyclical menstrual bleeding occurring over several consecutive cycles'. Objectively it is a total menstrual blood loss equal to or greater than 80 ml per menstruation...
  71. ncbi A Canadian, multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagia
    Jan Endrikat
    Bayer Inc, Toronto, Ontario, Canada
    J Obstet Gynaecol Can 31:340-7. 2009
    ..intrauterine system (LNG-IUS) compared with a combined oral contraceptive containing 1 mg norethindrone acetate and 20 mg ethinyl estradiol (OC1/20) in reducing menstrual blood loss (MBL) in women with idiopathic menorrhagia.
  72. ncbi Modern management of menorrhagia
    Joanne Protheroe
    National Primary Care Research and Development Centre, University of Manchester, Manchester, UK
    J Fam Plann Reprod Health Care 30:118-22. 2004
    b>Menorrhagia, defined clinically as menstrual blood loss in excess of 80 ml per cycle, is a common gynaecological complaint that presents both to primary and secondary care...
  73. ncbi Perioperative complication rates of primary and repeat hysteroscopic endometrial ablations
    Erin MacLean-Fraser
    Department of Obstetrics and Gynaecology, St Joseph s Health Care, 268 Grosvenor St, London, Ontario N6A 4V2, Canada
    J Am Assoc Gynecol Laparosc 9:175-7. 2002
    ..To determine perioperative complication rates at primary and repeat endometrial ablations...
  74. pmc Down-regulation of angiopoietin-1 expression in menorrhagia
    Peter Hewett
    Department of Reproductive and Vascular Biology, TheMedical School, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Am J Pathol 160:773-80. 2002
    ..Perturbation of this process is associated with menorrhagia, a common gynecological disorder that results in excessive menstrual bleeding...
  75. ncbi Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate
    Dror Meirow
    Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel
    Cancer 107:1634-41. 2006
    b>Menorrhagia is a serious complication in young female oncology patients who suffer from severe thrombocytopenia during myelosuppressive treatment...
  76. doi Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized study
    Yun Hwan Kim
    Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea
    Acta Haematol 121:37-41. 2009
    ..safety and achievement of the target hemoglobin level (Hb >or=10 g/dl) in patients with preoperative anemia due to menorrhagia who received intravenous iron sucrose compared with oral iron protein succinylate for anemia management.
  77. ncbi von Willebrand's disease and menorrhagia: prevalence, diagnosis, and management
    Jody L Kujovich
    Division of Hematology Medical Oncology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Am J Hematol 79:220-8. 2005
    The reported prevalence of von Willebrand's disease (vWD) is increased in women with menorrhagia, with current estimates ranging from 5% to 20%...
  78. ncbi Microwave endometrial ablation vs. rollerball electroablation for menorrhagia: a multicenter randomized trial
    Jay M Cooper
    Women s Health Research, Phoenix, Arizona, USA
    J Am Assoc Gynecol Laparosc 11:394-403. 2004
    To compare the effectiveness, safety, and acceptability of microwave endometrial ablation (MEA) with those of rollerball electroablation (REA) for the treatment of menorrhagia.
  79. ncbi Pregnancy after endometrial ablation: English literature review and case report
    Jenny S Y Lo
    Department of Obstetrics and Gynaecology, South Manchester University Hospitals NHS Trust, Manchester, UK
    J Minim Invasive Gynecol 13:88-91. 2006
    ..7%. We report what is to the best of our knowledge the first case of pregnancy after microwave endometrial ablation and review the outcomes of 74 pregnancies after various methods of endometrial destruction...
  80. ncbi A double-blind randomized trial comparing the Cavaterm and the NovaSure endometrial ablation systems for the treatment of dysfunctional uterine bleeding
    Jason Abbott
    James Cook University Hospital, Middleborough, United Kingdom
    Fertil Steril 80:203-8. 2003
    ..To compare two second-generation endometrial ablation systems in women with dysfunctional uterine bleeding (DUB) who want conservative surgical treatment...
  81. ncbi Microwave endometrial ablation for menorrhagia caused by large submucous myomas
    Yasushi Kanaoka
    Department of Obstetrics and Gynecology, Osaka City University Graduate School of Medicine, Osaka, Japan
    J Obstet Gynaecol Res 31:565-70. 2005
    ..the feasibility of microwave endometrial ablation (MEA), using a curved microwave applicator, in patients with menorrhagia caused by a submucous myoma greater than 3 cm in diameter, which is among the contraindications for ..
  82. pmc An integrated care pathway for menorrhagia across the primary-secondary interface: patients' experience, clinical outcomes, and service utilisation
    Sophia Julian
    Reproductive Sciences Section, Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester, UK
    Qual Saf Health Care 16:110-5. 2007
    ..quot;Referral" characterises a significant area of interaction between primary and secondary care. Despite advantages, it can be inflexible, and may lead to duplication...
  83. ncbi Cavaterm thermal balloon endometrial ablation versus hysteroscopic endometrial resection to treat menorrhagia: the French, multicenter, randomized study
    Jean Luc Brun
    Department of Obstetrics and Gynecology, Pellegrin University Hospital, Bordeaux, France
    J Minim Invasive Gynecol 13:424-30. 2006
    ..To compare the efficacy and safety of Cavaterm thermal balloon endometrial ablation with hysteroscopic endometrial resection...
  84. ncbi Microwave endometrial ablation for menorrhagia in patients with systemic disorders
    Yuanshu Qian
    Department of Gynecology, Second Affiliated Hospital of Zhejiang University, Hangzhou 310009, China
    Int J Gynaecol Obstet 91:32-5. 2005
    To evaluate the effectiveness of microwave endometrial ablation (MEA) in the treatment of menorrhagia in patients with severe systemic disease or medical conditions.
  85. ncbi Clinical outcomes and costs with the levonorgestrel-releasing intrauterine system or hysterectomy for treatment of menorrhagia: randomized trial 5-year follow-up
    Ritva Hurskainen
    Department of Obstetrics and Gynecology, University of Helsinki, Finland
    JAMA 291:1456-63. 2004
    Because menorrhagia is often a reason for seeking medical attention, it is important to consider outcomes and costs associated with alternative treatment modalities...
  86. ncbi Uterine volume and menstrual patterns in users of the levonorgestrel-releasing intrauterine system with idiopathic menorrhagia or menorrhagia due to leiomyomas
    Jarbas Magalhães
    Department of Obstetrics and Gynecology, Clinic of Gynecological Endocrinology, School of Medicine, Santa Casa de Sao Paulo, São Paulo 01221 900, Brazil
    Contraception 75:193-8. 2007
    ..of uterine leiomyomas in women using the levonorgestrel intrauterine system (LNG-IUS) to treat idiopathic menorrhagia (n=32) and menorrhagia due to leiomyomas (n=27)...
  87. ncbi Expression of aquaporin-1 in endometrial blood vessels in menorrhagia
    Miriam Mints
    Department of Clinical Science, Division of Obstetrics and Gynecology, Karolinska University Hospital Huddinge, Karolinska Institutet, S 14186 Stockholm, Sweden
    Int J Mol Med 19:407-11. 2007
    ..of AQP1 in endometrial blood vessels in normal cyclic endometrium as well as in endometrial biopsies of menorrhagia patients...
  88. ncbi Endometrial ablation in England--coming of age? An examination of hospital episode statistics 1989/1990 to 2004/2005
    Peter C Reid
    Directorate of Obstetrics and Gynaecology, Luton and Dunstable Hospital NHS Trust, Luton LU4 0DZ, United Kingdom
    Eur J Obstet Gynecol Reprod Biol 135:191-4. 2007
    ..To observe numbers and trends in endometrial ablation performed for heavy menstrual bleeding (HMB) in England...
  89. ncbi Treatment of menorrhagia associated with oral anticoagulation: efficacy and safety of the levonorgestrel releasing intrauterine device (Mirena coil)
    C N Pisoni
    Lupus Research Unit, The Rayne Institute, King s College London School of Medicine at Guy s, King s and St Thomas Hospital, UK
    Lupus 15:877-80. 2006
    b>Menorrhagia is common in women receiving oral anticoagulation. In healthy women, reductions of up to 90% of menstrual loss have been described with the levonorgestrel releasing intrauterine device (LNG-IUS)...
  90. pmc Treatments for heavy menstrual bleeding
    Anne Lethaby
    BMJ 327:1243-4. 2003
  91. pmc Trends in number of hysterectomies performed in England for menorrhagia: examination of health episode statistics, 1989 to 2002-3
    Peter C Reid
    Directorate of Obstetrics and Gynaecology, Luton and Dunstable Hospital NHS Trust, Luton LU4 0DZ
    BMJ 330:938-9. 2005
  92. ncbi Therapeutic effects of the levonorgestrel-releasing intrauterine system in the treatment of idiopathic menorrhagia
    Bilian Xiao
    National Research Institute for Family Planning, and Beijing Gynecology and Obstetrics Hospital, Beijing, People s Republic of China
    Fertil Steril 79:963-9. 2003
    To investigate the effect of the levonorgestrel-releasing intrauterine system (LNG-IUS) in the treatment of idiopathic menorrhagia.
  93. pmc Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid, and tranexamic acid
    J Bonnar
    Trinity College, Department of Obstetrics and Gynaecology, St James Hospital, Dublin, Ireland
    BMJ 313:579-82. 1996
    To compare the efficacy and acceptability of ethamsylate, mefenamic acid, and tranexamic acid for treating menorrhagia.
  94. ncbi Hysteroscopic transcervical endometrial resection versus thermal destruction for menorrhagia: a prospective randomized trial on satisfaction rate
    Massimiliano Pellicano
    Department of Obstetrics, Gynecology, and Reproductive Medicine, University of Naples Federico II, Italy
    Am J Obstet Gynecol 187:545-50. 2002
    The purpose of this study was to compare the satisfaction rate and the effectiveness of transcervical hysteroscopic endometrial resection and thermal destruction of the endometrium in the treatment of menorrhagia.
  95. ncbi Effectiveness of a computerized decision aid in primary care on decision making and quality of life in menorrhagia: results of the MENTIP randomized controlled trial
    Joanne Protheroe
    National Primary Care Research and Development Centre, University of Manchester, Manchester, United Kingdom
    Med Decis Making 27:575-84. 2007
    ..Computerized decision aids have the potential to increase patient involvement in the decision-making process. However, most published evidence concerning the effectiveness of decision aids is from secondary care...
  96. ncbi Quality of life instruments in studies of menorrhagia: a systematic review
    T Justin Clark
    Department of Obstetrics and Gynaecology, Birmingham Women s Hospital, Birmingham BI5 2TG, UK
    Eur J Obstet Gynecol Reprod Biol 104:96-104. 2002
    The use of quality of life (QoL) instruments in menorrhagia research is increasing but there is concern that not enough emphasis is placed on patient-focus in these measurements, i.e...
  97. ncbi Therapeutic use of levonorgestrel-releasing intrauterine system in women with menorrhagia: a pilot study(1)
    Ilza Monteiro
    Human Reproduction Unit, Department of Obstetrics and Gynecology, School of Medicine, Universidade Estadual de Campinas UNICAMP, Campinas, Brazil
    Contraception 65:325-8. 2002
    ..intrauterine system releasing 20 microg/day of levonorgestrel (LNG-IUS, Mirena) in the treatment of women with menorrhagia. It was a descriptive, prospective, non-comparative study...
  98. ncbi A randomized controlled trial of levonorgestrel releasing IUD and thermal balloon ablation in the treatment of menorrhagia
    Mehmet Soysal
    Pamukkale University, Department of Obstetrics and Gynecology, Denizli, Turkey
    Zentralbl Gynakol 124:213-9. 2002
    Our aim was to compare the treatment of menorrhagia either with a levonorgestrel-releasing intrauterine device or with endometrial thermal balloon ablation...
  99. ncbi Menorrhagia and bleeding disorders
    Ihab El-Hemaidi
    Department of Haematology, Queen Elizabeth Hospital, London, UK
    Curr Opin Obstet Gynecol 19:513-20. 2007
    b>Menorrhagia affects 30% of women in reproductive age. Once referred to a gynaecologist, possible causative bleeding disorders are not routinely investigated and the risk of surgical intervention is high...
  100. doi The risk of venous thromboembolism associated with the use of tranexamic acid and other drugs used to treat menorrhagia: a case-control study using the General Practice Research Database
    A Sundstrom
    Centre for Pharmacoepidemiology, Clinical Epidemiology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden
    BJOG 116:91-7. 2009
    ..To assess whether use of tranexamic acid is associated with an increased risk of venous thromboembolism (VTE)...
  101. doi A 41-year-old woman with menorrhagia, anemia, and fibroids: review of treatment of uterine fibroids
    Bradley Van Voorhis
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Rd, Iowa City, IA 52242, USA
    JAMA 301:82-93. 2009
    ..However, the case of Ms P, a 41-year-old woman with recurrent uterine fibroids, menorrhagia, anemia, and fatigue who wishes to retain fertility, illustrates the symptoms that require treatment...

Research Grants89

  1. Estrogen Dependency of Uterine Leiomyoma
    Ayman Al Hendy; Fiscal Year: 2007
    ..They are all significant cause of pelvic pain, menorrhagia, infertility, and pregnancy-related complications...
  2. Molecular and Clinical Biology of VWD
    Robert Montgomery; Fiscal Year: 2007
    ..The laboratory features, bleeding symptoms and scoring of a subgroup containing women who exhibit menorrhagia as a major symptom will be studied for bleeding score and laboratory VWF phenotyping Project 2 will define the ..
  3. Control of menstrual bleeding disturbances in women
    Ian Fraser; Fiscal Year: 2006
    ..This study aims to explore these possibilities in large scale clinical studies, scientific study of vascular and molecular changes in endometrium and with the exploration of molecular mechanisms in mice. ..
  4. PDE3 Inhibitors: Selective Blockers of Oocyte Maturation
    Jeffrey Jensen; Fiscal Year: 2007
    ..This approach is expected to provide a foundation for future Phase 1 trials of PDE3 inhibitors in humans. ..
  5. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1992
    ....
  6. Menopause Depression and Aging
    Joyce T Bromberger; Fiscal Year: 2010
    ..Increasing knowledge of the risks for depression in aging women and the factors that protect them from depression can identify targets for intervention at the prevention as well as the acute treatment level. ..
  7. DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORS
    David Archer; Fiscal Year: 2006
    ..If successful, DOX treatment could become an important adjuvant for treatment of this and possibly other inflammatory disorders effecting reproductive tract tissues. ..
  8. Short-Term vs Long-Term Treatment for Servere PMS
    Ellen Freeman; Fiscal Year: 2006
    ....
  9. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 1993
    ..Information on the course of PMS symptoms is important for understanding its occurrence and chronicity, which reduces the quality of life and affects the use of costly medical resources...
  10. TREATMENT EVALUATION IN PREMENSTRUAL SYNDROME PATIENTS
    Ellen Freeman; Fiscal Year: 2001
    ....
  11. Core symptoms and profiles in premenstrual syndrome
    Ellen Freeman; Fiscal Year: 2007
    ..Further information will contribute to improved health care for women in their reproductive years. ..
  12. EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARS
    Ellen W Freeman; Fiscal Year: 2010
    ..abstract_text> ..
  13. A Genome-Wide Association Study of Non-Hodgkin Lymphoma
    Christine Skibola; Fiscal Year: 2007
    ..The data generated from this study will provide a framework for further investigation within the NHL consortium, InterLymph. Results will later be combined with that from other InterLymph case-control studies in pooled analyses. ..
  14. Cardiac Channel Mutations in Sudden Infant Death Syndrome (SIDS)
    Michael Ackerman; Fiscal Year: 2007
    ....
  15. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2007
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  16. A Genome-Wide Association Study of Non-Hodgkin Lymphoma
    Christine F Skibola; Fiscal Year: 2010
    ..Results will later be combined with that from other InterLymph case-control studies in pooled analyses. ..
  17. Genetic Susceptibility to non-Hodgkin Lymphoma
    Christine Skibola; Fiscal Year: 2009
    ....
  18. Cardiac Channel Mutations in Sudden Infant Death Syndrome (SIDS)
    MICHAEL JOHN ACKERMAN; Fiscal Year: 2010
    ....
  19. Genetic Susceptibility to non-Hodgkin Lymphoma
    Christine F Skibola; Fiscal Year: 2010
    ....
  20. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2005
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  21. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2002
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  22. Training in Epidemiology and Clinical Trials (TECT)
    David Grimes; Fiscal Year: 2007
    ....
  23. PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSY
    Andrew Herzog; Fiscal Year: 2006
    ..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
  24. PRE-CLINICAL COMBINATION CHEMO- AND RADIOANTIBODY THERAP
    Rosalyn Blumenthal; Fiscal Year: 2004
    ..2) Therapy-induced changes in marker expression post therapy can be identified clinically in small samples of circulating tumor cells. ..
  25. Cardiac Channel Mutations in SIDS
    Michael Ackerman; Fiscal Year: 2005
    ..Such a discovery could have significant implications on attempts to further reduce the incidence of SIDS in our country and throughout the world. ..
  26. Alteration of HOX Gene Expression by Endocrine Disrupting Chemicals
    Hugh S Taylor; Fiscal Year: 2010
    ..We hypothesize that the effects are maintained long after exposure through epigenetic mechanisms such as methylation of HOX genes. ..
  27. HOX Gene Expression by Endocrine Disrupting Chemicals
    Hugh Taylor; Fiscal Year: 2005
    ..abstract_text> ..
  28. Center for Endometrial Biology and Endometriosis
    Hugh Taylor; Fiscal Year: 2007
    ..The Center also contains three Cores. An Administrative Core, a Cell and Tissue Core and Mouse Modeling Core will be used by each of the investigators and complete a comprehensive Center. ..
  29. HOX GENE EXPRESSION IN HUMAN ENDOMETRIUM
    Hugh Taylor; Fiscal Year: 2007
    ..These studies will further characterize the molecular mechanisms by which HOX expression is related to normal and pathologic endometrial development. ..
  30. Alteration of HOX Gene Expression by Endocrine Disrupting Chemicals
    Hugh Taylor; Fiscal Year: 2009
    ..We hypothesize that the effects are maintained long after exposure through epigenetic mechanisms such as methylation of HOX genes. ..