Genomes and Genes
Summary: Excessive uterine bleeding during MENSTRUATION.
Publications293 found, 100 shown here
- Levonorgestrel intrauterine system versus medical therapy for menorrhagiaJanesh Gupta
School of Clinical and Experimental Medicine, University of Birmingham, Birmingham, United Kingdom
N Engl J Med 368:128-37. 2013b>Menorrhagia is a common problem, yet evidence to inform decisions about therapy is limited...
- Low-dose mifepristone in treatment of uterine leiomyoma: a randomised double-blind placebo-controlled clinical trialMadhu Bagaria
Department of Obstetrics and Gynaecology, University College of Medical Sciences, Delhi, India
Aust N Z J Obstet Gynaecol 49:77-83. 2009..To evaluate the effect of low-dose mifepristone on leiomyoma-related symptoms, uterine and leiomyoma in women with symptomatic leiomyomata...
- Long-term treatment of menorrhagia with levonorgestrel intrauterine system versus endometrial resectionIlkka Rauramo
The Finnish Medical Society Duodecim, Helsinki, Finland
Obstet Gynecol 104:1314-21. 2004The purpose of this study was to compare the long-term efficacy of the levonorgestrel intrauterine system and transcervical resection of the endometrium in the treatment of menorrhagia.
- Age and the prevalence of bleeding disorders in women with menorrhagiaClaire S Philipp
Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
Obstet Gynecol 105:61-6. 2005A study was conducted to evaluate the frequency and types of hemostatic defects occurring in adolescent and perimenopausal-age women diagnosed with menorrhagia.
- The experience of heavy menstrual bleeding: a systematic review and meta-ethnography of qualitative studiesRuth Garside
PenTAG, Peninsula Medical School, Exeter, UK
J Adv Nurs 63:550-62. 2008..This paper is a report of a systematic review and meta-ethnography of the experience of heavy menstrual bleeding...
- The Ontario Uterine Fibroid Embolization Trial. Part 2. Uterine fibroid reduction and symptom relief after uterine artery embolization for fibroidsGaylene Pron
Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 79:120-7. 2003..To evaluate fibroid uterine volume reduction, symptom relief, and patient satisfaction with uterine artery embolization (UAE) for symptomatic fibroids...
- The levonorgestrel-releasing intrauterine system in heavy menstrual bleeding: a benefit-risk reviewAndrew M Kaunitz
Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, FL 32209, USA
Drugs 72:193-215. 2012..In conclusion, the LNG-IUS is an effective treatment option for women with HMB, including those with underlying organic pathology or bleeding disorders...
- Menorrhagia I: measured blood loss, clinical features, and outcome in women with heavy periods: a survey with follow-up dataPamela E Warner
Division of Community Health Sciences, University of Edinburgh Medical School, Obstetrics and Gynaecology, University of Edinburgh, Centre for Reproductive Biology, Edinburgh, Scotland, United Kingdom
Am J Obstet Gynecol 190:1216-23. 2004b>Menorrhagia is defined as blood loss of >80 mL, but in routine clinical practice measurement is seldom undertaken. Our aim was to identify the features of the clinical history that best predict menorrhagic blood loss.
- Treatment of uterine myoma with 5 or 10mg mifepristone daily during 6 months, post-treatment evolution over 12 months: double-blind randomised clinical trialJosep Ll Carbonell Esteve
Mediterránea Médica Clinic, Valencia, Castello, Valencian Country, Spain
Eur J Obstet Gynecol Reprod Biol 161:202-8. 2012..To evaluate the efficacy and safety of 5 and 10mg doses of mifepristone for 6 months for the treatment of uterine fibroids and to check those results at 1 year post-treatment...
- Second generation endometrial ablation techniques for heavy menstrual bleeding: network meta-analysisJ P Daniels
University of Birmingham, Clinical Trials Unit, Birmingham B15 2TT, UK
BMJ 344:e2564. 2012..To determine the relative effectiveness of second generation ablation techniques in the treatment of heavy menstrual bleeding...
- Continuous oral or intramuscular medroxyprogesterone acetate versus the levonorgestrel releasing intrauterine system in the treatment of perimenopausal menorrhagia: a randomized, prospective, controlled clinical trial in female smokersT Kucuk
Department of Obstetrics and Gynecology, GATA School of Medicine, Ankara, Turkey
Clin Exp Obstet Gynecol 35:57-60. 2008To compare the efficacy of three progestin regimens in perimenopausal menorrhagia.
- Efficacy, acceptability and side effects of the levonorgestrel intrauterine system for menorrhagiaA Kriplani
Department of Obstetrics and Gynecology, All India Institute of Medical Sciences, New Delhi, India
Int J Gynaecol Obstet 97:190-4. 2007To evaluate the efficacy, acceptability, and possible side effects of a levonorgestrel-releasing intrauterine system for menorrhagia.
- Work loss associated with increased menstrual loss in the United StatesIsabelle Côté
Institute of Health Economics, Edmonton, Alberta, Canada
Obstet Gynecol 100:683-7. 2002..To estimate the effect of increased menstrual flow on the loss of work...
- Why women consult with increased vaginal bleeding: a case-control studyMark Shapley
Primary Care Sciences Research Centre, Keele University, Staffordshire
Br J Gen Pract 52:108-13. 2002....
- Platelet functional defects in women with unexplained menorrhagiaC S Philipp
Division of Hematology and Women s Health Institute, UMDNJ Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903, USA
J Thromb Haemost 1:477-84. 2003b>Menorrhagia is a common clinical problem and is unexplained in more than 50% of women...
- Effective treatment of heavy menstrual bleeding with estradiol valerate and dienogest: a randomized controlled trialJeffrey T Jensen
Department of Obstetrics and Gynecology, Oregon Health and Science University, Portland, Oregon 97239, USA
Obstet Gynecol 117:777-87. 2011....
- Levonorgestrel-releasing intrauterine system and endometrial ablation in heavy menstrual bleeding: a systematic review and meta-analysisAndrew M Kaunitz
Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Florida, USA
Obstet Gynecol 113:1104-16. 2009..To compare the effects of the levonorgestrel intrauterine system and endometrial ablation in reducing heavy menstrual bleeding...
- Determination of total menstrual blood lossK M Wyatt
Academic Department of Obstetrics and Gynaecology, North Staffordshire Hospital, Stoke-on-Trent, United Kingdom
Fertil Steril 76:125-31. 2001..SETTING: Academic menorrhagia research clinic...
- Hysterectomy, endometrial destruction, and levonorgestrel releasing intrauterine system (Mirena) for heavy menstrual bleeding: systematic review and meta-analysis of data from individual patientsL J Middleton
Birmingham Clinical Trials Unit, University of Birmingham, Birmingham B15 2TT
BMJ 341:c3929. 2010....
- Levonorgestrel-releasing intrauterine system or medroxyprogesterone for heavy menstrual bleeding: a randomized controlled trialAndrew M Kaunitz
Department of Obstetrics and Gynecology, University of Florida College of Medicine Jacksonville, Jacksonville, Florida, USA
Obstet Gynecol 116:625-32. 2010..To compare the efficacy and safety of the levonorgestrel-releasing intrauterine system and oral medroxyprogesterone acetate in the treatment of idiopathic heavy menstrual bleeding...
- An epidemiological survey of symptoms of menstrual loss in the communityMark Shapley
Primary Care Sciences Research Centre, Keele University, Staffordshire
Br J Gen Pract 54:359-63. 2004..The evidence for this advice is based on the prevalence of symptoms in women with gynaecological malignancy or within specialist clinics. There are no studies on the incidence of symptoms within the community...
- Factor VII DeficiencyGuglielmo Mariani
Dipartimento di Medicina Interna e Sanita Pubblica, Universita dell Aquila, L Aquila 67010, Italy
Semin Thromb Hemost 35:400-6. 2009..In females, menorrhagia is prevalent and affects two thirds of the patients of fertile age...
- Effective treatment of heavy and/or prolonged menstrual bleeding with an oral contraceptive containing estradiol valerate and dienogest: a randomized, double-blind Phase III trialI S Fraser
Department of Obstetrics and Gynaecology, Central Clinical School, D02 QEII Research Institute for Mothers and Infants, University of Sydney, Sydney, NSW 2006, Australia
Hum Reprod 26:2698-708. 2011..This double-blind trial investigated the efficacy and safety of estradiol valerate/dienogest (E(2)V/DNG) for the treatment of heavy menstrual bleeding without recognizable organic pathology...
- A Scottish postal survey suggested that the prevailing clinical preoccupation with heavy periods does not reflect the epidemiology of reported symptoms and problemsMiriam Santer
Tayside Centre for General Practice, Mackenzie Building, Dundee, UK
J Clin Epidemiol 58:1206-10. 2005..To determine the prevalence of self-reported menstrual symptoms and problem periods and explore their relationship with sociodemographic factors, parity, long-standing illness, and hormonal contraceptive use...
- Levonorgestrel-releasing intrauterine system compared to low dose combined oral contraceptive pills for idiopathic menorrhagia: a randomized clinical trialMamdouh M Shaaban
Faculty of Medicine, Department of Obstetrics and Gynecology, Assiut University, Assiut 71526, Egypt
Contraception 83:48-54. 2011This study compared the efficacy of the levonorgestrel-releasing intrauterine system (LNG-IUS) to low dose combined oral contraceptive pills (COC) in the management of idiopathic menorrhagia.
- A Canadian, multicentre study comparing the efficacy of a levonorgestrel-releasing intrauterine system to an oral contraceptive in women with idiopathic menorrhagiaJan Endrikat
Bayer Inc, Toronto, Ontario, Canada
J Obstet Gynaecol Can 31:340-7. 2009..intrauterine system (LNG-IUS) compared with a combined oral contraceptive containing 1 mg norethindrone acetate and 20 mg ethinyl estradiol (OC1/20) in reducing menstrual blood loss (MBL) in women with idiopathic menorrhagia.
- Tranexamic acid treatment for heavy menstrual bleeding: a randomized controlled trialAndrea S Lukes
Carolina Women s Research and Wellness Center, Durham, North Carolina 27713, USA
Obstet Gynecol 116:865-75. 2010..To assess the efficacy and safety of an oral formulation of tranexamic acid for the treatment of heavy menstrual bleeding...
- Randomised comparative trial of the levonorgestrel intrauterine system and mefenamic acid for the treatment of idiopathic menorrhagia: a multiple analysis using total menstrual fluid loss, menstrual blood loss and pictorial blood loss assessment chartsPeter C Reid
Luton and Dunstable NHS Trust, Luton, UK
BJOG 112:1121-5. 2005To compare the efficacy and tolerability of the levonorgestrel intrauterine system (LNG IUS) with mefenamic acid in the management of objective idiopathic menorrhagia.
- The prevalence of disorders of haemostasis in adolescents with menorrhagia referred to a haemophilia treatment centreS Mikhail
Department of Medicine, Rochester General Hospital, 1415 Portland Avenue, Rochester, NY 14621, USA
Haemophilia 13:627-32. 2007b>Menorrhagia at the time of menarche is relatively common and historically attributed primarily to immaturity of the pituitary-ovarian-uterine axis...
- Treatment of menorrhagia with an LNG-IUSPaivi Pakarinen
Department of Obstetrics and Gynecology, Helsinki University Central Hospital, Helsinki, PO Box 140, HUCH, 00029, Finland
Contraception 75:S118-22. 2007b>Menorrhagia, also known as heavy menstrual bleeding, is defined as a menstrual blood loss is greater than 80 mL...
- Can the levonorgestrel intrauterine system replace surgical treatment for the management of menorrhagia?Rani Nagrani
Department of Obstetrics and Gynaecology, Singleton Hospital, Swansea, UK
BJOG 109:345-7. 2002b>Menorrhagia is a common gynaecological condition for which medical treatment is often ineffective and a large number of women undergo major surgery...
- Efficacy of the levonorgestrel intrauterine system in treating menorrhagia: actualities and ambiguitiesAmaju Ikomi
Department of Obstetrics and Gynaecology, Basildon Hospital, Essex, UK
J Fam Plann Reprod Health Care 28:99-100. 2002..Data extraction and synthesis: After perusal, each relevant publication was summarised and appraised in terms of whether it contained information relevant to the stated objective...
- Menorrhagia due to abnormalities of the platelet function: evaluation of two young patientsYesim Aydinok
Division of Pediatric Hematology, Department of Pediatrics, School of Medicine, Ege University, Izmir, Turkey
Pediatr Int 49:106-8. 2007
- A cost-utility analysis of hysterectomy, endometrial resection and ablation and medical therapy for menorrhagiaJoyce H S You
Centre for Pharmacoeconomics Research, School of Pharmacy, The Chinese University of Hong Kong, China
Hum Reprod 21:1878-83. 2006..intrauterine system (LNG-IUS) and oral medical therapy] are available for management of menorrhagia. The objective of this study was to compare the cost and quality-adjusted life-years (QALYs) gained by these ..
- Improving results of hysteroscopic submucosal myomectomy for menorrhagia by concomitant endometrial ablationFranklin D Loffer
Department of Obstetrics and Gynecology, University of Arizona, Phoenix, Arizona 85013, USA
J Minim Invasive Gynecol 12:254-60. 2005To evaluate the effect of endometrial ablation on the outcome of premenopausal patients undergoing hysteroscopic myomectomy for menorrhagia or menometrorrhagia
- Bleeding disorders in teenagers presenting with menorrhagiaYasmin Jayasinghe
Department of Paediatric and Adolescent Gynaecology, Royal Children s Hospital, Melbourne, Australia
Aust N Z J Obstet Gynaecol 45:439-43. 2005..To assess the prevalence of bleeding disorders and establish the clinical variables that are predictive of a bleeding disorder in adolescent women...
- The Ontario Uterine Fibroid Embolization Trial. Part 1. Baseline patient characteristics, fibroid burden, and impact on lifeGaylene Pron
Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
Fertil Steril 79:112-9. 2003..To determine baseline characteristics of women undergoing uterine artery embolization (UAE) for symptomatic fibroids...
- Prognostic factors for the success of thermal balloon ablation in the treatment of menorrhagiaM Y Bongers
Department of Obstetrics and Gynecology, St Joseph Hospital, The, Veldhoven, Netherlands
Obstet Gynecol 99:1060-6. 2002To identify predictive factors that will ensure successful menorrhagia treatment using hot fluid balloon endometrial ablation.
- Depressive symptoms as predictors of discontinuation of treatment of menorrhagia by levonorgestrel-releasing intrauterine systemMarko Elovainio
National Research and Development Centre for Welfare and Health, P O Box 220, FIN 00531, Helsinki, Finland
Int J Behav Med 14:70-5. 2007It has been shown that levonorgestrel-releasing intrauterine system (LNG-IUS) is an effective treatment of menorrhagia. However, the discontinuation rate of LNG-IUS treatment is high, and little is known about the actual reasons ..
- Abnormal bleeding patterns associated with menorrhagia in women in the community and in women presenting to primary careMark Shapley
Primary Care Sciences Research Centre, Keele University, Staffordshire ST5 5BG, UK
Fam Pract 24:532-7. 2007There is an assumption that in women with menorrhagia 'excessive menstrual loss in regular cycles is the most common clinical presentation' yet epidemiological studies show irregular cycles and bleeding are common.
- Three-dimensional power Doppler study of endometrial and subendometrial microvascularization in women with intrauterine device-induced menorrhagiaAkmal El-Mazny
Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt
Fertil Steril 99:1912-5. 2013..microvascularization, using three-dimensional (3D) power Doppler ultrasound, in women with intrauterine device (IUD)-induced menorrhagia; and whether those potential findings could predict the risk of bleeding before IUD insertion.
- First- versus second-generation endometrial ablation devices for treatment of menorrhagia: a systematic review, meta-analysis and appraisal of economic evaluationsJamie Kroft
Sunnybrook Health Sciences Centre, Department of Obstetrics and Gynaecology, University of Toronto, Toronto ON
J Obstet Gynaecol Can 35:1010-9. 2013..of using second-generation endometrial ablation devices compared to first-generation devices for treatment of menorrhagia in pre-menopausal women. The secondary objective was to compare the second-generation devices with one another.
- Evaluation of a screening tool for bleeding disorders in a US multisite cohort of women with menorrhagiaClaire S Philipp
Division of Hematology, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Am J Obstet Gynecol 204:209.e1-7. 2011The purpose of this study was to determine the usefulness of a simple screening tool for bleeding disorders in a multisite population of women with menorrhagia.
- The spectrum of haemostatic characteristics of women with unexplained menorrhagiaC H Miller
Division of Blood Disorders, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
Haemophilia 17:e223-9. 2011While an estimated 13% of women with unexplained menorrhagia have von Willebrand disease (VWD), the frequency of other potential bleeding disorders has been uncertain...
- Clinical practice guidelines on menorrhagia: management of abnormal uterine bleeding before menopauseH Marret
centre hospitalo universitaire de Tours, Hopital Bretonneau, Service de Gynecologie, Tours 37044 cédex 1, France
Eur J Obstet Gynecol Reprod Biol 152:133-7. 2010Normal menstrual periods last 3-6 days and involve blood loss of up to 80ml. Menorrhagia is defined as menstrual periods lasting more than 7 days and/or involving blood loss greater than 80ml...
- Managing perimenopausal menorrhagiaKirsten Duckitt
Medical Staff Office, Campbell River and District Hospital, Campbell River, British Columbia, Canada
Maturitas 66:251-6. 2010b>Menorrhagia is a significant health problem for many women. It increases with age and peaks during the perimenopause...
- Adolescent menorrhagia due to platelet function disorderNazli Hossain
Department of Obstetrics and Gynecology Unit 3, Dow University of Health Sciences and Civil Hospital Karachi
J Pak Med Assoc 60:127-9. 2010The prevalence of menorrhagia in adolescent populations with bleeding disorders varies between 14% to 48%...
- The cost-effectiveness of the levonorgestrel-releasing intrauterine system for the treatment of idiopathic heavy menstrual bleeding in the United StatesMichael L Ganz
United BioSource Corporation, Lexington, MA 02420, USA
Value Health 16:325-33. 2013..Our objective was to evaluate the cost-effectiveness of the levonorgestrel-releasing intrauterine system (LNG-IUS) compared with other therapies for idiopathic heavy menstrual bleeding...
- An assessment of economic measures used in menorrhagia: a systematic reviewSabina Sanghera
Health Economics Unit, School of Health and Population Sciences, Public Health Building, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK Electronic address
Soc Sci Med 98:149-53. 2013b>Menorrhagia', or heavy menstrual bleeding, is a common problem affecting women...
- von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagiaA Dilley
Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, GA, USA
Obstet Gynecol 97:630-6. 2001To estimate the prevalence of von Willebrand disease and other bleeding disorders in women with and without diagnosed menorrhagia.
- Outcomes after rollerball endometrial ablation for menorrhagiaC Dutton
Department of Obstetrics and Gynecology, Kaiser Permanente Medical Center, Santa Clara, California, USA
Obstet Gynecol 98:35-9. 2001OBJECTIVE: To evaluate the outcomes of women undergoing rollerball endometrial ablation for menorrhagia and to identify factors associated with those outcomes...
- Bleeding disorders: A common cause of menorrhagia in adolescentsJ A Bevan
Department of Pediatrics, Section of Pediatric Hematology and Oncology, Medical College and Children's Hospital of Wisconsin, Milwaukee, WI 53201-2178, USA
J Pediatr 138:856-61. 2001OBJECTIVE: To determine the frequency of underlying bleeding disorders in adolescents with menorrhagia. STUDY DESIGN: We retrospectively reviewed the charts of all girls, aged 10 to 19 years, who presented to our children's hospital for ..
- Levonorgestrel-releasing intrauterine system vs. endometrial thermal ablation for menorrhagiaTheodoros D Theodoridis
1st Department of Obstetrics and Gynaecology, Papageorgiou General Hospital, Aristotle University of Thessaloniki, Periferiaki Odos Thessalonikis, N Efkarpia, Thessaloniki, Greece
Hormones (Athens) 8:60-4. 2009To evaluate the efficacy of a Levonorgestrel-releasing Intrauterine System (LNG-IUS) in controlling menorrhagia in comparison with endometrial thermal rollerball ablation.
- A cost-utility analysis of microwave endometrial ablation versus thermal balloon endometrial ablationMary M Kilonzo
Health Economics Research Unit, University of Aberdeen, UK
Value Health 13:528-34. 2010..To evaluate the cost-effectiveness of microwave endometrial ablation (MEA) and thermal balloon endometrial ablation (TBALL) for heavy menstrual bleeding...
- Tranexamic acid: a review of its use in the management of menorrhagiaKeri Wellington
Adis International Limited, Auckland, New Zealand
Drugs 63:1417-33. 2003..In a number of small clinical studies in women with idiopathic menorrhagia, tranexamic acid 2-4...
- Heavy menstrual bleeding: delivering patient-centred careMiriam Santer
Br J Gen Pract 58:151-2. 2008
- Efficacy of bipolar radiofrequency endometrial ablation vs thermal balloon ablation for management of menorrhagia: A population-based cohortSherif A El-Nashar
Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Minim Invasive Gynecol 16:692-9. 2009..To compare the efficacy of bipolar radiofrequency ablation (RFA) and thermal balloon ablation (TBA) using treatment failure and postprocedure amenorrhea as outcome measures...
- Screening women with menorrhagia for underlying bleeding disorders: the utility of the platelet function analyser and bleeding timeC S Philipp
Division of Hematology, Department of Medicine, UMDNJ Robert Wood Johnson Medical School, New Brunswick, NJ 08903, USA
Haemophilia 11:497-503. 2005b>Menorrhagia is a very common clinical problem among women of reproductive age and recent studies have suggested that underlying bleeding disorders, particularly von Willebrand's deficiency and platelet function defects, are prevalent in ..
- Clinical outcomes from a randomised comparison of Microwave Endometrial Ablation with Thermal Balloon endometrial ablation for the treatment of heavy menstrual bleedingA M Sambrook
Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Aberdeen, UK
BJOG 116:1038-45. 2009..To compare the clinical outcomes of microwave endometrial ablation and thermal balloon ablation for the treatment of heavy menstrual bleeding...
- A randomised controlled trial comparing the Cavaterm endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleedingJed Hawe
Department of Obstetrics and Gynaecology, Countess of Chester Hospital, UK
BJOG 110:350-7. 2003..To compare the effectiveness of the Cavaterm thermal balloon endometrial ablation system with the Nd:YAG laser for the treatment of dysfunctional uterine bleeding...
- Diagnosis and treatment of menorrhagiaR Hurskainen
Department of Obstetrics and Gynecology, University of Helsinki, Finland
Acta Obstet Gynecol Scand 86:749-57. 2007..In western countries, about 5% of women of reproductive age will seek help for menorrhagia annually...
- Increased vaginal bleeding: the reasons women give for consulting primary careM Shapley
Primary Care Sciences Research Centre, Keele University, Staffordshire, UK
J Obstet Gynaecol 23:48-50. 2003..This does not distinguish consulters and non-consulters and is not reflected in objective measures of psychological distress. Clinicians should focus initially on treating the presenting physical symptoms...
- Pictorial blood loss assessment chart in the evaluation of heavy menstrual bleeding: diagnostic accuracy compared to alkaline hematinMahmoud S Zakherah
Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
Gynecol Obstet Invest 71:281-4. 2011..The pictorial blood assessment chart (PBAC) is a method for evaluation of menstrual blood loss (MBL). This study was conducted to evaluate the accuracy of the PBAC score in diagnosing MBL compared to alkaline hematin as a gold standard...
- Oral contraceptives and DDAVP nasal spray: patterns of use in managing vWD-associated menorrhagia: a single-institution studyLawrence S Amesse
Section of Pediatric Adolescent Gynecology, Division of Reproductive Endocrinology and Infertility, Wright State University School of Medicine, Dayton, Ohio 45409, USA
J Pediatr Hematol Oncol 27:357-63. 2005..to examine patterns of use for oral contraceptive and desmopressin acetate nasal spray, both used in managing menorrhagia in adolescents with von Willebrand disease (vWD)...
- Menorrhagia in adolescents with inherited bleeding disordersClaudia Chi
Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
J Pediatr Adolesc Gynecol 23:215-22. 2010We reviewed the management and treatment outcomes of menorrhagia in adolescents with inherited bleeding disorders and assessed the impact of menorrhagia on their quality of life.
- von Willebrand disease in women with menorrhagia: a systematic reviewMeena Shankar
Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
BJOG 111:734-40. 2004To determine the prevalence of von Willebrand disease in women presenting with menorrhagia.
- Effect of Iron Therapy on Platelet Function among Iron-Deficient Women with Unexplained MenorrhagiaOlga Meltem Akay
Department of Hematology, Eskisehir Osmangazi University Medical School, Eskisehir, Turkey
Pathophysiol Haemost Thromb 36:80-3. 2008..This study was performed to evaluate the effect of iron therapy on platelet function among women with unexplained menorrhagia in order to better understand possible interactions between iron deficiency anemia and platelet behavior and ..
- Health-related quality of life and patient satisfaction after global endometrial ablation for menorrhagia in women with bleeding disorders: a follow-up survey and systematic reviewSherif A El-Nashar
Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN 55905, USA
Am J Obstet Gynecol 202:348.e1-7. 2010..The purpose of this study was to describe health-related quality of life and satisfaction after global endometrial ablation in women with bleeding disorders and a systematic review of the literature...
- Estimating menstrual blood loss in women with normal and excessive menstrual fluid volumeI S Fraser
Sydney Centre for Reproductive Health Research, Family Planning NSW, Sydney, Australia
Obstet Gynecol 98:806-14. 2001..To examine the relationship between total fluid volume at menstruation and the volume of blood loss, and to assess the feasibility of using total fluid volume to estimate menstrual blood loss...
- A randomized controlled trial of hysterectomy or levonorgestrel-releasing intrauterine system in the treatment of menorrhagia-effect on FSH levels and menopausal symptomsK Halmesmäki
Department of Obstetrics and Gynecology, Central Hospital of Päijät Häme, Keskussairaalankatu 7, 15850 Lahti, Finland
Hum Reprod 19:378-82. 2004..The purpose of this study was to compare the effects of hysterectomy and a levonorgestrel-releasing intrauterine system (LNG-IUS) on serum FSH levels and menopausal symptoms...
- A survey of gynecologists concerning menorrhagia: perceptions of bleeding disorders as a possible causeAnne Dilley
Centers for Disease Control and Prevention, National Center for Infectious Diseases, Hematologic Diseases Branch, Atlanta, Georgia 30333, USA
J Womens Health Gend Based Med 11:39-44. 2002..to determine perceptions and practices of American gynecologists when treating with a woman complaining of menorrhagia, specifically with regard to an underlying bleeding disorder as a potential cause...
- Assessment of menorrhagia by total menstrual fluid lossP C Reid
Luton and Dunstable NHS Trust, Luton, UK
J Obstet Gynaecol 26:438-41. 2006Half of the women presenting with heavy periods do not have objective menorrhagia. In the normal woman, blood is a minority component of total menstrual volume...
- Multisite management study of menorrhagia with abnormal laboratory haemostasis: a prospective crossover study of intranasal desmopressin and oral tranexamic acidPeter A Kouides
Mary M Gooley Hemophilia Center and the Rochester General Hospital, Rochester, NY 14621, USA
Br J Haematol 145:212-20. 2009The optimal management of menorrhagia among women with abnormal laboratory haemostasis is uncertain...
- Referral for menstrual problems: cross sectional survey of symptoms, reasons for referral, and managementP Warner
Public Health Sciences, Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG
BMJ 323:24-8. 2001To describe the menstrual experience of women referred for menstrual problems, in particular menorrhagia (excessive menstrual loss), and to assess associations with reasons for referral given by their general practitioners, the women's ..
- [Surgical therapeutic management for menorrhagia]J P Lucot
Hopital Jeanne de Flandre, CHU de Lille, pôle de gynécologie, 59037 Lille Cedex, France
J Gynecol Obstet Biol Reprod (Paris) 37:S398-404. 2008..The possibility of further surgery should however be discussed pre-operatively. In case of hysterectomy, abdominal route is not recommended, and vaginal or laparoscopic routes are preferred...
- Inherited bleeding disorders in Indian women with menorrhagiaR Saxena
Department of Haematology, All India Institute of Medical Sciences, New Delhi, India
Haemophilia 9:193-6. 2003In order to define the prevalence of haemostatic defects in women presenting with menorrhagia in our region, the coagulation data on women bleeders investigated in the Department of Haematology, AIIMS, were analysed...
- Medium-term clinical outcome of women with menorrhagia treated by rollerball endometrial ablation versus abdominal hysterectomy with conservation of at least one ovaryH A Mousa
Department of Obstetrics and Gynecology, Liverpool Women's Hospital, Liverpool University, Liverpool, United Kingdom
Acta Obstet Gynecol Scand 80:442-6. 2001..endometrial ablation or abdominal hysterectomy with conservation of at least one ovary for the treatment of menorrhagia. METHOD: Between March 1992 to June 1997, 91 women underwent rollerball endometrial ablation and 78 women had ..
- Expression of angiopoietins 1, 2 and their common receptor tie-2 in relation to the size of endothelial lining gaps and expression of VEGF and VEGF receptors in idiopathic menorrhagiaMiriam Mints
Department of Clinical Science, Division of Obstetrics and Gynaecology, Karolinska Institutet at Karolinska University Hospital Huddinge, Stockholm, Sweden
Fertil Steril 94:701-7. 2010To investigate whether idiopathic menorrhagia (IM) is associated with alterations of the vascular expression of angiopoietin-1, angiopoietin-2, and tie-2 receptor.
- Is balloon ablation as effective as endometrial electroresection in the treatment of menorrhagia?M Y Bongers
Department of Obstetrics and Gynecology, St Joseph Hospital, Veldhoven, The Netherlands
J Laparoendosc Adv Surg Tech A 10:85-92. 2000Hot-fluid balloon therapy is a recently introduced, relatively simple endometrial ablation procedure for menorrhagia. Because it is thought to be safer than other ablation procedures, it would be superior to other types of ablation if it ..
- Evaluation and treatment of menorrhagia in an adolescent populationGary N Frishman
Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown Medical School, Providence, Rhode Island 02905, USA
J Minim Invasive Gynecol 15:682-8. 2008..Adolescents present with unique issues related to their age, involvement of family members, different differential diagnosis when compared to an older populations, and challenges associated with their evaluation and treatment...
- The levonorgestrel-releasing intrauterine system provides a reliable, long-term treatment option for women with idiopathic menorrhagiaJan Endrikat
Bayer HealthCare, Berlin, Germany
Arch Gynecol Obstet 285:117-21. 2012Idiopathic menorrhagia (IM) is an important clinical challenge. The levonorgestrel-releasing intrauterine system (LNG IUS) provides an effective treatment option as shown by multiple small clinical studies...
- Menorrhagia in general practice--disease or illnessN O'Flynn
Lambeth Walk Group Practice, London, UK
Soc Sci Med 50:651-61. 2000b>Menorrhagia is a common presentation in primary care. The gynaecological literature defines menorrhagia, as the loss of 80 ml or more of blood per period and guidelines for treatment are based on this definition...
- Bipolar radiofrequency endometrial ablation compared with hydrothermablation for dysfunctional uterine bleeding: a randomized controlled trialJosien P M Penninx
Department of Obstetrics and Gynecology, Maxima Medical Centre, Veldhoven, The Netherlands
Obstet Gynecol 116:819-26. 2010To compare the effectiveness of two second-generation ablation techniques, bipolar radiofrequency impedance-controlled endometrial ablation and hydrothermablation, in the treatment of menorrhagia.
- Randomised controlled trial of bipolar radio-frequency endometrial ablation and balloon endometrial ablationMarlies Y Bongers
Department of Obstetrics and Gynaecology, Maxima Medical Centre, Veldhoven, The Netherlands
BJOG 111:1095-102. 2004To compare the effectiveness of two second-generation ablation techniques, bipolar radio-frequency impedance-controlled endometrial ablation (NovaSure) and balloon ablation (ThermaChoice), in the treatment of menorrhagia.
- Hematological abnormalities in adolescent menorrhagiaE Oral
Department of Obstetrics and Gynecology, Cerrahpasa Medical School, Istanbul University, Turkey
Arch Gynecol Obstet 266:72-4. 2002The purpose of this study is to determine the frequency of underlying hematological disorders as the cause of acute adolescent menorrhagia.
- Clinical outcome of levonorgestrel intra-uterine system in idiopathic menorrhagiaB Chattopdhyay
Department of Obstetrics and Gynaecology, Lady Hardinge Medical College, New Delhi, India
Eur Rev Med Pharmacol Sci 15:764-8. 2011To evaluate the efficacy, acceptability and side effects of levonorgestrel intrauterine system in patients with idiopathic menorrhagia.
- The effect of levonorgestrel-releasing intrauterine system use on menstrual blood loss and the hemostatic, fibrinolytic/inhibitor systems in women with menorrhagiaS C L Koh
Department of Obstetrics and Gynaecology, National University of Singapore, Yong Loo Lin School of Medicine, National University Hospital, Singapore, Singapore
J Thromb Haemost 5:133-8. 2007b>Menorrhagia is known to be associated with uterine fibroids, adenomyosis, pelvic infections, endometrial polyps and clotting defects...
- Microwave endometrial ablation for menorrhagia: outcome at 2 years--experience of a district general hospitalB Sharma
Department of Obstetrics and Gynaecology, James Paget Hospital, Great Yarmouth, UK
J Obstet Gynaecol 24:916-9. 2004..There were a few minor complications but no uterine perforation or emergency hysterectomies in the group studied...
- Review of quality of life: menorrhagia in women with or without inherited bleeding disordersM Shankar
Department of Obstetrics and Gynaecology, Royal Free Hospital, London, UK
Haemophilia 14:15-20. 2008The objectives of this study were to identify the impact of menorrhagia on the health-related quality of life (HRQOL) of women in general and those with inherited bleeding disorders and to identify the commonly used tools in assessing ..
- Menorrhagia: an updateM K Oehler
Department of Obstetrics and Gynecology, Westmead Hospital, University of Sydney, Westmead, NSW, Australia
Acta Obstet Gynecol Scand 82:405-22. 2003b>Menorrhagia is defined as a 'complaint of heavy cyclical menstrual bleeding occurring over several consecutive cycles'. Objectively it is a total menstrual blood loss equal to or greater than 80 ml per menstruation...
- Modern management of menorrhagiaJoanne Protheroe
National Primary Care Research and Development Centre, University of Manchester, Manchester, UK
J Fam Plann Reprod Health Care 30:118-22. 2004b>Menorrhagia, defined clinically as menstrual blood loss in excess of 80 ml per cycle, is a common gynaecological complaint that presents both to primary and secondary care...
- Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetateDror Meirow
Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel
Cancer 107:1634-41. 2006b>Menorrhagia is a serious complication in young female oncology patients who suffer from severe thrombocytopenia during myelosuppressive treatment...
- A randomized clinical trial of a levonorgestrel-releasing intrauterine system and a low-dose combined oral contraceptive for fibroid-related menorrhagiaGamal H Sayed
Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt
Int J Gynaecol Obstet 112:126-30. 2011To compare the efficacy of a levonorgestrel-releasing intrauterine system (LNG-IUS) with that of a low-dose combined oral contraceptive (COC) in reducing fibroid-related menorrhagia.
- Levonorgestrel-releasing intrauterine device insertion ameliorates leiomyoma-dependent menorrhagia among women of reproductive age without a significant regression in the uterine and leiomyoma volumesMehmet Murat Naki
Obstetrics and Gynecology Department, Dr Lutfi Kirdar Kartal Research and Training Hospital, Kartal, Istanbul, Turkey
Fertil Steril 94:371-4. 2010..LNG-IUD can be considered as a simple and effective alternative to surgical treatment in the management of leiomyoma-dependent menorrhagia of reproductive-age women.
- Surgery for menorrhagia within English regions: variation in rates of endometrial ablation and hysterectomyD A Cromwell
Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, UK
BJOG 116:1373-9. 2009To examine variation between English regions in the use of surgery (endometrial ablation or hysterectomy) for the treatment of menorrhagia.
- Down-regulation of angiopoietin-1 expression in menorrhagiaPeter Hewett
Department of Reproductive and Vascular Biology, TheMedical School, University of Birmingham, Edgbaston, Birmingham, United Kingdom
Am J Pathol 160:773-80. 2002..Perturbation of this process is associated with menorrhagia, a common gynecological disorder that results in excessive menstrual bleeding...
- Treatment of menorrhagia with the levonorgestrel intrauterine system versus endometrial resectionO Istre
Department of Obstetrics and Gynecology, Central Hospital of Hedmark County, Hamar, Norway
Fertil Steril 76:304-9. 2001Treatment of menorrhagia with levonorgestrel intrauterine system (LNG IUS) and transcervical resection.
- Safety and usefulness of intravenous iron sucrose in the management of preoperative anemia in patients with menorrhagia: a phase IV, open-label, prospective, randomized studyYun Hwan Kim
Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea
Acta Haematol 121:37-41. 2009..safety and achievement of the target hemoglobin level (Hb >or=10 g/dl) in patients with preoperative anemia due to menorrhagia who received intravenous iron sucrose compared with oral iron protein succinylate for anemia management.
- Outpatient microwave endometrial ablation: 5-year follow-up of a randomised controlled trial without endometrial preparation versus standard day surgery with endometrial preparationA M Sambrook
Department of Obstetrics and Gynaecology, Aberdeen Royal Infirmary, Foresterhill, Aberdeen, UK
BJOG 117:493-6. 2010..It can be concluded that microwave endometrial ablation outcomes are not affected in the long term by undertaking the procedure in the postmenstrual phase in an outpatient setting...
- Perioperative complication rates of primary and repeat hysteroscopic endometrial ablationsErin MacLean-Fraser
Department of Obstetrics and Gynaecology, St Joseph s Health Care, 268 Grosvenor St, London, Ontario N6A 4V2, Canada
J Am Assoc Gynecol Laparosc 9:175-7. 2002..To determine perioperative complication rates at primary and repeat endometrial ablations...
- Migraine is associated with menorrhagia and endometriosisGretchen E Tietjen
Department of Neurology, Medical College of Ohio, Toledo 43614, USA
Headache 46:422-8. 2006To evaluate the frequency of menorrhagia and endometriosis in female migraineurs compared to age-matched women without headache.
- Prevention of the Complications of Hemophilia Thru Hemophilila Treatment CentersMD WALSH; Fiscal Year: 2010..Some aims will be directly transferable to other chronic disease populations in the general public such as the evaluation of obesity and menorrhagia.
- Feasibility of the Von Willebrand Disease Minimize TrialMARGARET VICTORIA RAGNI; Fiscal Year: 2013..interleukin-11 (rhIL-11) with tranexamic acid (TA), the current recommended non-hormonal treatment, to reduce menorrhagia in women with type 1 von Willebrand disease (VWD)...
- Extra / Intra-cellular Signaling in Novel 3-Dimensional Human Leiomyoma CulturesWILLIAM HENRY CATHERINO; Fiscal Year: 2013..provided by applicant): Uterine leiomyoma play a significant role in miscarriage, infertility, preterm labor, menorrhagia, pelvic pain, and urinary incontinence...
- Zimmerman Program for the Molecular and Clinical Biology of VWDRobert R Montgomery; Fiscal Year: 2013..Some newer pilot studies will also study the impact of VWD on clinical menorrhagia and Quality of Life studies in VWD patients...
- SURGICAL TREATMENTS OUTCOMES PROJECT FOR DUB (STOP-DUB)Kay Dickersin; Fiscal Year: 2000..Estimates of prevalence for menorrhagia range from 9-20% of women, and metrorrhagia occurs in 53 women per 1,000...
- CENTER FOR ALTERNATIVE MEDICINE IN WOMENS HEALTHFredi Kronenberg; Fiscal Year: 1999..on 4 problems that affect a large number of women, namely, menopausal hot flashes, fibroids, dysmenorrhea and menorrhagia. The center will identify practitioners in the following 4 program areas who are interested in evaluating their ..
- PDE3 Inhibitors: Selective Blockers of Oocyte MaturationJeffrey Jensen; Fiscal Year: 2007..This approach is expected to provide a foundation for future Phase 1 trials of PDE3 inhibitors in humans. ..
- Control of menstrual bleeding disturbances in womenIan Fraser; Fiscal Year: 2006..This study aims to explore these possibilities in large scale clinical studies, scientific study of vascular and molecular changes in endometrium and with the exploration of molecular mechanisms in mice. ..
- DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORSDavid Archer; Fiscal Year: 2006..If successful, DOX treatment could become an important adjuvant for treatment of this and possibly other inflammatory disorders effecting reproductive tract tissues. ..
- CAREER DEVELOPMENT IN WOMEN'S HEALTH RESEARCH AND GENDE*Ellen Freeman; Fiscal Year: 2006..The BIRCWH program will track the career trajectories of Scholars and will continue to serve as a resource in terms of career counseling and research advice. [unreadable] [unreadable]..
- Core symptoms and profiles in premenstrual syndromeEllen Freeman; Fiscal Year: 2008..Further information will contribute to improved health care for women in their reproductive years. [unreadable] [unreadable] [unreadable] [unreadable]..
- CARDIOPROTECTIVE EFFECT--NEW CHELATORS FOR THALASSEMIAChaim Hershko; Fiscal Year: 2001..abstract_text> ..
- Obstacles to Answering Physicians' Patient-Care QuestionJohn Ely; Fiscal Year: 2003..Benefit: By identifying areas where knowledge resources fail to meet the needs of physicians, we will provide recommendations to help knowledge base developers better meet those needs. ..
- Prophylactic Ibuprofen: Effect on IUD Continuation RatesDavid Hubacher; Fiscal Year: 2003..In the US, ibuprofen may help spur renewed interest in the most cost effective and efficacious reversible contraceptive method available. ..
- Menopause Depression and AgingJoyce T Bromberger; Fiscal Year: 2010..Increasing knowledge of the risks for depression in aging women and the factors that protect them from depression can identify targets for intervention at the prevention as well as the acute treatment level. ..
- EPIDEMIOLOGIC STUDY OF THE LATE REPRODUCTIVE YEARSEllen W Freeman; Fiscal Year: 2010..abstract_text> ..
- A Genome-Wide Association Study of Non-Hodgkin LymphomaChristine F Skibola; Fiscal Year: 2010..The data generated from this study will provide a framework for further investigation within the NHL consortium, InterLymph. Results will later be combined with that from other InterLymph case-control studies in pooled analyses. ..
- PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSYAndrew Herzog; Fiscal Year: 2008..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
- HOX GENE EXPRESSION IN HUMAN ENDOMETRIUMHugh Taylor; Fiscal Year: 2007..These studies will further characterize the molecular mechanisms by which HOX expression is related to normal and pathologic endometrial development. ..