dehydration

Summary

Summary: The condition that results from excessive loss of water from a living organism.

Top Publications

  1. ncbi Assessing hydration status: the elusive gold standard
    Lawrence E Armstrong
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT 06269 1110, USA
    J Am Coll Nutr 26:575S-584S. 2007
  2. pmc Isolation and functional analysis of Arabidopsis stress-inducible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehydration stress 1 promoter
    Lam Son Phan Tran
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 16:2481-98. 2004
  3. pmc Photosynthesis under drought and salt stress: regulation mechanisms from whole plant to cell
    M M Chaves
    Instituto Superior de Agronomia, Technical University of Lisbon, Lisbon, Portugal
    Ann Bot 103:551-60. 2009
  4. doi Regulation of barley miRNAs upon dehydration stress correlated with target gene expression
    Melda Kantar
    Biological Sciences and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey
    Funct Integr Genomics 10:493-507. 2010
  5. ncbi Identification of drought-induced microRNAs in rice
    Botao Zhao
    State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai 200031, China
    Biochem Biophys Res Commun 354:585-90. 2007
  6. ncbi Human hydration indices: acute and longitudinal reference values
    Lawrence E Armstrong
    Human Performance Laboratory, University of Connecticut, Storrs, CT, USA
    Int J Sport Nutr Exerc Metab 20:145-53. 2010
  7. pmc Genome-wide survey and expression analysis of the plant-specific NAC transcription factor family in soybean during development and dehydration stress
    Dung Tien Le
    Signaling Pathway Research Unit, Plant Science Center, RIKEN Yokohama Institute, Suehiro cho, Tsurumi, Japan
    DNA Res 18:263-76. 2011
  8. doi Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics
    Kaoru Urano
    Gene Discovery Research Group, RIKEN Plant Science Center, 3 1 1 Koyadai, Tsukuba, Ibaraki, Japan
    Plant J 57:1065-78. 2009
  9. ncbi Is this child dehydrated?
    Michael J Steiner
    Department of Pediatrics, University of North Carolina School of Medicine, and Robert Wood Johnson Clinical Scholars Program, Chapel Hill 27599 7593, USA
    JAMA 291:2746-54. 2004
  10. pmc Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression
    Yoh Sakuma
    Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo 113 8657, Japan
    Proc Natl Acad Sci U S A 103:18822-7. 2006

Detail Information

Publications357 found, 100 shown here

  1. ncbi Assessing hydration status: the elusive gold standard
    Lawrence E Armstrong
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, CT 06269 1110, USA
    J Am Coll Nutr 26:575S-584S. 2007
    ....
  2. pmc Isolation and functional analysis of Arabidopsis stress-inducible NAC transcription factors that bind to a drought-responsive cis-element in the early responsive to dehydration stress 1 promoter
    Lam Son Phan Tran
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 16:2481-98. 2004
    The MYC-like sequence CATGTG plays an important role in the dehydration-inducible expression of the Arabidopsis thaliana EARLY RESPONSIVE TO DEHYDRATION STRESS 1 (ERD1) gene, which encodes a ClpA (ATP binding subunit of the caseinolytic ..
  3. pmc Photosynthesis under drought and salt stress: regulation mechanisms from whole plant to cell
    M M Chaves
    Instituto Superior de Agronomia, Technical University of Lisbon, Lisbon, Portugal
    Ann Bot 103:551-60. 2009
    ..Photosynthesis, together with cell growth, is among the primary processes to be affected by water or salt stress...
  4. doi Regulation of barley miRNAs upon dehydration stress correlated with target gene expression
    Melda Kantar
    Biological Sciences and Bioengineering Program, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey
    Funct Integr Genomics 10:493-507. 2010
    We aim to identify conserved and dehydration responsive microRNAs (miRNAs) in Hordeum vulgare (barley). A total of 28 new barley miRNAs belonging to 18 distinct miRNA families were identified...
  5. ncbi Identification of drought-induced microRNAs in rice
    Botao Zhao
    State Key Laboratory of Molecular Biology, Institute of Biochemistry and Cell Biology, Shanghai 200031, China
    Biochem Biophys Res Commun 354:585-90. 2007
    ..Sequence analysis revealed occurrence of two proximate DREs (dehydration-responsive element) in the upstream of the MIR-169g, suggesting that miR-169g expression may be regulated ..
  6. ncbi Human hydration indices: acute and longitudinal reference values
    Lawrence E Armstrong
    Human Performance Laboratory, University of Connecticut, Storrs, CT, USA
    Int J Sport Nutr Exerc Metab 20:145-53. 2010
    ..These findings provide euhydration reference values and hydration extremes for 7 commonly used indices in free-living, healthy, active men who were not exercising in a hot environment or training strenuously...
  7. pmc Genome-wide survey and expression analysis of the plant-specific NAC transcription factor family in soybean during development and dehydration stress
    Dung Tien Le
    Signaling Pathway Research Unit, Plant Science Center, RIKEN Yokohama Institute, Suehiro cho, Tsurumi, Japan
    DNA Res 18:263-76. 2011
    ..identified 58 of the 152 GmNACs as putative stress-responsive genes, including eight previously reported dehydration-responsive GmNACs...
  8. doi Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics
    Kaoru Urano
    Gene Discovery Research Group, RIKEN Plant Science Center, 3 1 1 Koyadai, Tsukuba, Ibaraki, Japan
    Plant J 57:1065-78. 2009
    ..Adaptation by plants to dehydration stress is a complex biological process that involves global changes in gene expression and metabolite ..
  9. ncbi Is this child dehydrated?
    Michael J Steiner
    Department of Pediatrics, University of North Carolina School of Medicine, and Robert Wood Johnson Clinical Scholars Program, Chapel Hill 27599 7593, USA
    JAMA 291:2746-54. 2004
    The ability to assess the degree of dehydration quickly and accurately in infants and young children often determines patient treatment and disposition.
  10. pmc Dual function of an Arabidopsis transcription factor DREB2A in water-stress-responsive and heat-stress-responsive gene expression
    Yoh Sakuma
    Graduate School of Agricultural and Life Sciences, University of Tokyo, Tokyo 113 8657, Japan
    Proc Natl Acad Sci U S A 103:18822-7. 2006
    Transcription factor DREB2A interacts with a cis-acting dehydration-responsive element (DRE) sequence and activates expression of downstream genes involved in drought- and salt-stress response in Arabidopsis thaliana...
  11. doi Effect of exercise-induced dehydration on time-trial exercise performance: a meta-analysis
    Eric D B Goulet
    Research Centre on Aging Faculty of Physical Education and Sports, University of Sherbrooke, Quebec, Canada
    Br J Sports Med 45:1149-56. 2011
    To use the meta-analytical procedures to determine the magnitude of the effect of exercise-induced dehydration (EID) upon time-trial (TT) exercise performance.
  12. ncbi ATriple Iron triathlon leads to a decrease in total body mass but not to dehydration
    Beat Knechtle
    St Gallen Health Center, St Gallen, Switzerland
    Res Q Exerc Sport 81:319-27. 2010
    A loss in total body mass during an ultraendurance performance is usually attributed to dehydration. We identified the changes in total body mass, fat mass, skeletal muscle mass, and selected markers of hydration status in 31 male ..
  13. pmc Dynamic changes in genome-wide histone H3 lysine 4 methylation patterns in response to dehydration stress in Arabidopsis thaliana
    Karin van Dijk
    Center for Biotechnology, University of Nebraska, Lincoln, NE 68588, USA
    BMC Plant Biol 10:238. 2010
    ..We have no knowledge of chromatin modifications taking place at genes whose transcription has been down-regulated or on the genome-wide chromatin modification patterns that occur during the plant's response to dehydration stress.
  14. doi Molecular characterization of stress-inducible GmNAC genes in soybean
    Lam Son Phan Tran
    Division of Plant Sciences, National Center for Soybean Biotechnology, University of Missouri, Columbia, MO 65211, USA
    Mol Genet Genomics 281:647-64. 2009
    ..we prescreened and re-confirmed by quantitative real-time PCR analysis that nine GmNAC genes are induced by dehydration stress with differential induction levels in both shoot and root...
  15. ncbi Assessing hydration status
    Stavros A Kavouras
    Laboratory of Nutrition and Clinical Dietetics, Department of Nutrition and Dietetics, Harokopio University, Athens, Greece
    Curr Opin Clin Nutr Metab Care 5:519-24. 2002
    ..Understanding the importance of euhydration in humans in order to ensure good health in various situations, the purpose of this review is to examine the available techniques in assessing hydration status...
  16. ncbi Cryptobiosis--a peculiar state of biological organization
    J S Clegg
    Bodega Marine Laboratory and Molecular and Cellular Biology, University of California Davis, Bodega Bay, CA 94923, USA
    Comp Biochem Physiol B Biochem Mol Biol 128:613-24. 2001
    ..Basic research on cryptobiosis has resulted in unpredicted applications that are of substantial benefit to the human condition and a few of these are described briefly...
  17. pmc Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment
    Alessandra Livraghi
    Cystic Fibrosis Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, 27599, USA
    J Immunol 182:4357-67. 2009
    ..Thus, manipulation of multiple pathways will likely be required to treat the complex pathogenesis caused by airway surface dehydration.
  18. pmc Pregame urine specific gravity and fluid intake by National Basketball Association players during competition
    Kristin L Osterberg
    Gatorade Sports Science Institute, 617 West Main Street, Barrington, IL 60010, USA
    J Athl Train 44:53-7. 2009
    ..020). Whether initial hydration status based on a urine measure is related to subsequent drinking response during exercise or athletic competition is unclear...
  19. ncbi Hydration and muscular performance: does fluid balance affect strength, power and high-intensity endurance?
    Daniel A Judelson
    Human Performance Laboratory, Department of Kinesiology, University of Connecticut, Storrs, Connecticut, USA
    Sports Med 37:907-21. 2007
    ....
  20. doi Effects of athletes' muscle mass on urinary markers of hydration status
    Nassim Hamouti
    Exercise Physiology Laboratory at Toledo, University of Castilla La Mancha, Avda Carlos III, S N, 45071 Toledo, Spain
    Eur J Appl Physiol 109:213-9. 2010
    ..Our data suggest that athletes with large muscle mass (i.e., rugby players) are prone to be incorrectly classified as hypohydrated based on U(sg)...
  21. doi An ultratriathlon leads to a decrease of body fat and skeletal muscle mass--the Triple Iron Triathlon Austria 2006
    Beat Knechtle
    Gesundheitszentrum St Gallen, St Gallen, Switzerland
    Res Sports Med 16:97-110. 2008
    ..06). There is no association between total race time and the loss of BM (r(2) = 0.06), %BF (r(2) = 0.10), and SM (r2 = 0.11). No significant correlation (p > 0.05, r(2)= 0.43) was found between the initial SM and loss of SM...
  22. doi Dehydration in hospital-admitted stroke patients: detection, frequency, and association
    Anne Rowat
    Edinburgh Napier University, School of Nursing and Midwifery and Social Care, Edinburgh, Scotland
    Stroke 43:857-9. 2012
    We aimed to determine the frequency of dehydration, risk factors, and associations with outcomes at hospital discharge after stroke.
  23. pmc Identification of cis-acting promoter elements in cold- and dehydration-induced transcriptional pathways in Arabidopsis, rice, and soybean
    Kyonoshin Maruyama
    Biological Resources and Post harvest Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Ibaraki 305 8686, Japan
    DNA Res 19:37-49. 2012
    ..In Arabidopsis, cis-acting promoter elements involved in cold- and dehydration-responsive gene expression have been extensively analysed; however, the characteristics of such cis-acting ..
  24. doi Analysis of the nuclear proteome of the resurrection plant Xerophyta viscosa in response to dehydration stress using iTRAQ with 2DLC and tandem mass spectrometry
    Kamal Omer Abdalla
    Department of Molecular and Cellular Biology, University of Cape Town, Private Bag, Rondebosch 7701, South Africa
    J Proteomics 75:2361-74. 2012
    Xerophyta viscosa Baker (family Velloziaceae) is a desiccation tolerant plant which survives extremes of dehydration down to 5% relative water content (RWC) and resumes full physiological activity within 80h of rehydration...
  25. doi Saliva indices track hypohydration during 48h of fluid restriction or combined fluid and energy restriction
    Samuel J Oliver
    School of Sport, Health and Exercise Sciences, Bangor University, Bangor LL57 2PZ, UK
    Arch Oral Biol 53:975-80. 2008
    ..Following the 48h periods, UFR and Sosm were assessed after acute exercise dehydration and rehydration.
  26. pmc The crucial role of plant mitochondria in orchestrating drought tolerance
    Owen K Atkin
    Research School of Biological Sciences, Australian National University, Canberra, Australia
    Ann Bot 103:581-97. 2009
    ..In contrast to the large number of studies assessing drought impacts on photosynthesis, relatively little attention has been devoted to understanding how mitochondrial respiratory metabolism is altered under water stress conditions...
  27. ncbi Effects of acute dehydration on brain morphology in healthy humans
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, United Kingdom
    Hum Brain Mapp 30:291-8. 2009
    b>Dehydration can affect brain structure which has important implications for human health. In this study, we measured regional changes in brain structure following acute dehydration...
  28. ncbi Hyponatremic dehydration as a presentation of cystic fibrosis
    Yolanda Ballestero
    Hospital Universitario 12 de Octubre, Madrid, Spain
    Pediatr Emerg Care 22:725-7. 2006
    The purpose of this study is to present a case report of a child with hyponatremic dehydration diagnosed after CF and to review the cases of 13 patients with CF who had the same initial presentation in our hospital.
  29. ncbi Voluntary dehydration in runners despite favorable conditions for fluid intake
    Dennis Passe
    Gatorade Sports Science Institute, Barrington, IL 60010, USA
    Int J Sport Nutr Exerc Metab 17:284-95. 2007
    ..b>Dehydration averaged 1.9% +/- 0.8% of initial body weight (a mean sweat loss of 21.6 +/- 5.1 mL.kg-1.h-1)...
  30. ncbi Blood and urinary measures of hydration status during progressive acute dehydration
    L A Popowski
    Department of Exercise Science, University of Iowa, Iowa City, IA 52242, USA
    Med Sci Sports Exerc 33:747-53. 2001
    ..Posm, urine osmolarity (Uosm), and Usg were measured at 1%, 3%, and 5% dehydration, and 30 and 60 min of recovery (rec). Subjects consumed water in recovery equal to their loss of body weight...
  31. doi Overexpression of AtNHX5 improves tolerance to both salt and drought stress in Broussonetia papyrifera (L.) Vent
    Meiru Li
    Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, People s Republic of China
    Tree Physiol 31:349-57. 2011
    ....
  32. ncbi Adrenal splanchnic innervation modulates adrenal cortical responses to dehydration stress in rats
    Yvonne M Ulrich-Lai
    Department of Surgery, University of Minnesota, Minneapolis, 55455, USA
    Neuroendocrinology 76:79-92. 2002
    ..plasma corticosterone that were attenuated by splanchnic nerve transection, in the absence of changes in post-dehydration plasma ACTH...
  33. pmc Decline of leaf hydraulic conductance with dehydration: relationship to leaf size and venation architecture
    Christine Scoffoni
    Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles, California 90095 1606, USA
    Plant Physiol 156:832-43. 2011
    ..Because xylem embolism during dehydration also reduces K(leaf), we hypothesized that higher major vein density would also reduce hydraulic vulnerability...
  34. doi Reference change values for monitoring dehydration
    Samuel N Cheuvront
    U S Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Natick, MA 01760 5007, USA
    Clin Chem Lab Med 49:1033-7. 2011
    b>Dehydration is a common medical problem requiring heuristic evaluation...
  35. doi Dehydration affects brain structure and function in healthy adolescents
    Matthew J Kempton
    Centre for Neuroimaging Sciences, Institute of Psychiatry, King s College London, London, SE5 8AF, United Kingdom
    Hum Brain Mapp 32:71-9. 2011
    It was recently observed that dehydration causes shrinkage of brain tissue and an associated increase in ventricular volume...
  36. ncbi Saliva parameters as potential indices of hydration status during acute dehydration
    Neil P Walsh
    School of Sport, Health and Exercise Sciences, University of Wales, Bangor, United Kingdom
    Med Sci Sports Exerc 36:1535-42. 2004
    ..of hydration, we compared changes in these parameters with changes in plasma osmolality during progressive dehydration. Secondly, we compared the sensitivity of saliva parameters to track hydration changes with the sensitivity of ..
  37. pmc Children with severe malnutrition: can those at highest risk of death be identified with the WHO protocol?
    Kathryn Maitland
    Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
    PLoS Med 3:e500. 2006
    ....
  38. doi Identification of extracellular matrix proteins of rice (Oryza sativa L.) involved in dehydration-responsive network: a proteomic approach
    Aarti Pandey
    National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India
    J Proteome Res 9:3443-64. 2010
    Water-deficit or dehydration impairs almost all physiological processes and greatly influences the geographical distribution of many crop species...
  39. ncbi Effect of water deprivation on cognitive-motor performance in healthy men and women
    Gabor Szinnai
    Division of Endocrinology, Diabetes and Clinical Nutrition, Department of Internal Medicine, University Hospital, CH 4031 Basel, Switzerland
    Am J Physiol Regul Integr Comp Physiol 289:R275-80. 2005
    Whether mental performance is affected by slowly progressive moderate dehydration induced by water deprivation has not been examined previously...
  40. ncbi Constraints of tolerance: why are desiccation-tolerant organisms so small or rare?
    Peter Alpert
    Department of Biology, University of Massachusetts, Amherst, MA 01003, USA
    J Exp Biol 209:1575-84. 2006
    ....
  41. ncbi Evidence for airway surface dehydration as the initiating event in CF airway disease
    R C Boucher
    CF Pulmonary Research and Treatment Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7248, USA
    J Intern Med 261:5-16. 2007
    ..Amongst the most productive hypotheses at present is the ''low airway surface liquid (ASL) volume'' or ''dehydration'' hypothesis...
  42. pmc Genetic basis of drought resistance at reproductive stage in rice: separation of drought tolerance from drought avoidance
    Bing Yue
    National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research Wuhan, Huazhong Agricultural University, Wuhan, China
    Genetics 172:1213-28. 2006
    ..Only a small portion of QTL for fitness- and yield-related traits overlapped with QTL for root traits, indicating that DT and DA had distinct genetic bases...
  43. ncbi Activation of glucosidase via stress-induced polymerization rapidly increases active pools of abscisic acid
    Kwang Hee Lee
    Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790 784, Korea
    Cell 126:1109-20. 2006
    ..b>Dehydration rapidly induces polymerization of AtBG1, resulting in a 4-fold increase in enzymatic activity...
  44. pmc Causes of decreased photosynthetic rate and metabolic capacity in water-deficient leaf cells: a critical evaluation of mechanisms and integration of processes
    David W Lawlor
    Plant Sciences, Centre for Crop Improvement, Rothamsted Research, Harpenden, Herts, UK
    Ann Bot 103:561-79. 2009
    ..The relative importance of g(s) and A(pot), and how they are affected by WD, are reviewed with respect to light intensity and to experimental approaches...
  45. ncbi Dehydration confounds the assessment of brain atrophy
    T Duning
    Department of Neurology, University of Munster, Albert Schweitzer Str 22, 48129 Munster, Germany
    Neurology 64:548-50. 2005
    ..The authors show that dehydration and rehydration can significantly change brain volume: lack of fluid intake for 16 hours decreased brain volume ..
  46. pmc C4 photosynthesis and water stress
    Oula Ghannoum
    Centre for Plant and Food Science, University of Western Sydney, South Penrith DC, NSW, Australia
    Ann Bot 103:635-44. 2009
    ..Major gaps in our knowledge in this area are identified and further required research is suggested...
  47. ncbi Influence of raised plasma osmolality on clinical outcome after acute stroke
    A Bhalla
    Department of Public Health Sciences, Guy s, King s and St Thomas Hospital School of Medicine, Guy s and St Thomas Hospital, London, England
    Stroke 31:2043-8. 2000
    ..Studies of the effect of dehydration on stroke outcome are limited...
  48. ncbi Accuracy of urine specific gravity and osmolality as indicators of hydration status
    Robert A Oppliger
    Iowa Wrestling Research, Iowa City, IA 52240, USA
    Int J Sport Nutr Exerc Metab 15:236-51. 2005
    To reduce the adverse consequences of exertion-related and acute intentional dehydration research has focused on monitoring hydration status...
  49. ncbi The effects of dehydration on brain volume -- preliminary results
    J M Dickson
    Department of Biomedical Science, The University of Sheffield, Sheffield, UK
    Int J Sports Med 26:481-5. 2005
    ..This is the first study to investigate the relationship between dehydration and changes in the volume of the brain and the cerebral ventricles...
  50. pmc Analysis of natural variation in bermudagrass (Cynodon dactylon) reveals physiological responses underlying drought tolerance
    Haitao Shi
    Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, China
    PLoS ONE 7:e53422. 2012
    ..Taken together, our results indicated that natural variation of drought stress tolerance in bermudagrass varieties might be largely related to the induced changes of water status, osmolyte accumulation and antioxidant defense system...
  51. ncbi Saliva flow rate, total protein concentration and osmolality as potential markers of whole body hydration status during progressive acute dehydration in humans
    Neil P Walsh
    School of Sport, Health and Exercise Sciences, University of Wales, Bangor LL57 2PX, UK
    Arch Oral Biol 49:149-54. 2004
    ..saliva flow rate, total protein concentration and osmolality are sensitive non-invasive markers of whole body hydration status, we compared changes in these parameters with changes in body mass during progressive acute dehydration.
  52. ncbi The role of a gene cluster for trehalose metabolism in dehydration tolerance of the filamentous cyanobacterium Anabaena sp. PCC 7120
    Akiyoshi Higo
    Department of Molecular Biology, Faculty of Science, Saitama University, 255 Shimo ohkubo, Sakura ku, Saitama City, Saitama 338 8570, Japan
    Microbiology 152:979-87. 2006
    ..PCC 7120 was up-regulated markedly upon dehydration. However, the amount of trehalose accumulated during dehydration was small, whereas a large amount of sucrose ..
  53. doi Rhododendron catawbiense plasma membrane intrinsic proteins are aquaporins, and their over-expression compromises constitutive freezing tolerance and cold acclimation ability of transgenic Arabidopsis plants
    Yanhui Peng
    Department of Horticulture, Iowa State University, Ames, IA, USA
    Plant Cell Environ 31:1275-89. 2008
    Extracellular freezing results in cellular dehydration caused by water efflux, which is likely regulated by aquaporins (AQPs)...
  54. pmc Chemical clearing and dehydration of GFP expressing mouse brains
    Klaus Becker
    Department of Bioelectronics, Vienna University of Technology, FKE, Vienna, Austria
    PLoS ONE 7:e33916. 2012
    ..Chemical clearing, staining, and embedding of biological samples mostly requires careful foregoing tissue dehydration. The commonly applied tissue dehydration medium is ethanol, which also can markedly impair GFP fluorescence...
  55. doi Dehydration and vernalization treatments identify overlapping molecular networks impacting endodormancy maintenance in leafy spurge crown buds
    Münevver Doğramaci
    Biosciences Research Laboratory, USDA Agricultural Research Service, 1605 Albrecht Blvd N, Fargo, ND 58102 2765, USA
    Funct Integr Genomics 11:611-26. 2011
    ..In this study, the effects of dehydration stress on vegetative growth and flowering potential from endodormant UABs of leafy spurge was monitored...
  56. doi Dehydration-responsive reversible and irreversible changes in the extracellular matrix: comparative proteomics of chickpea genotypes with contrasting tolerance
    Deepti Bhushan
    National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India
    J Proteome Res 10:2027-46. 2011
    b>Dehydration is the most crucial environmental factor that limits plant growth, development, and productivity affecting agriculture throughout the world...
  57. doi The Arabidopsis trithorax-like factor ATX1 functions in dehydration stress responses via ABA-dependent and ABA-independent pathways
    Yong Ding
    University of Nebraska Center for Biotechnology and Center for Plant Science Innovation, 1901 Vine Street, Lincoln, NE 68588, USA
    Plant J 66:735-44. 2011
    ..Arabidopsis trithorax-like factor ATX1, which trimethylates histone H3 at lysine 4 (H3K4me3), is involved in dehydration stress signaling in both abscisic acid (ABA)-dependent and ABA-independent pathways...
  58. doi Proteome analysis of leaves of the desiccation-tolerant grass, Sporobolus stapfianus, in response to dehydration
    Melvin J Oliver
    USDA ARS PGRU, Columbia, MO, USA
    Phytochemistry 72:1273-84. 2011
    ..Understanding how plants respond to dehydration is an important prerequisite for developing strategies for crop improvement in drought tolerance...
  59. doi A study of the role of gene TaMYB2 and an associated SNP in dehydration tolerance in common wheat
    Bharti Garg
    International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, 110067, India
    Mol Biol Rep 39:10865-71. 2012
    ..the first time are reporting the identification of a synonymous single nucleotide polymorphism associated with dehydration tolerance at 458th bp (an A/G transition) in the TaMYB2 gene of wheat (Triticum aestivum L...
  60. doi Mechanisms of aerobic performance impairment with heat stress and dehydration
    Samuel N Cheuvront
    US Army Research Institute of Environmental Medicine, Thermal and Mountain Medicine Division, Kansas St, Natick, MA 01760 5007, USA
    J Appl Physiol (1985) 109:1989-95. 2010
    ..When dehydration exceeds 3% of total body water (2% of body mass) then aerobic performance is consistently impaired independent ..
  61. doi Differential proteomic responses to water stress induced by PEG in two creeping bentgrass cultivars differing in stress tolerance
    Chenping Xu
    Department of Plant Biology and Pathology, Rutgers University, New Brunswick, NJ 08901, United States
    J Plant Physiol 167:1477-85. 2010
    ..Our results suggest that proteins involved in membrane synthesis, cell wall loosening, cell turgor maintenance, and antioxidant defense may play roles in perennial grass adaptation to PEG-induced water stress...
  62. doi Biological variation and diagnostic accuracy of dehydration assessment markers
    Samuel N Cheuvront
    US Army Research Institute of Environmental Medicine, Natick, MA 01760 5007, USA
    Am J Clin Nutr 92:565-73. 2010
    Well-recognized markers for static (one time) or dynamic (monitoring over time) dehydration assessment have not been rigorously tested for their usefulness in clinical, military, and sports medicine communities.
  63. pmc Enhanced abscisic acid-mediated responses in nia1nia2noa1-2 triple mutant impaired in NIA/NR- and AtNOA1-dependent nitric oxide biosynthesis in Arabidopsis
    Jorge Lozano-Juste
    Instituto de Biologia Molecular y Celular de Plantas, Consejo Superior de Investigaciones Cientificas Universidad Politecnica de Valencia, Ciudad Politécnica de Innovación, 46022 Valencia, Spain
    Plant Physiol 152:891-903. 2010
    ..seed dormancy, hypersensitivity to abscisic acid (ABA) in seed germination and establishment, as well as dehydration resistance...
  64. pmc Heat shock proteins contribute to mosquito dehydration tolerance
    Joshua B Benoit
    Department of Entomology, The Ohio State University, Columbus, OH 43210, United States
    J Insect Physiol 56:151-6. 2010
    This study examines the responses of heat shock protein transcripts, Hsp70 and Hsp90, to dehydration stress in three mosquito species, Aedes aegypti, Anopheles gambiae and Culex pipiens...
  65. pmc Dehydration-responsive nuclear proteome of rice (Oryza sativa L.) illustrates protein network, novel regulators of cellular adaptation, and evolutionary perspective
    Mani Kant Choudhary
    National Institute of Plant Genome Research, New Delhi, India
    Mol Cell Proteomics 8:1579-98. 2009
    Water deficit or dehydration is the most crucial environmental constraint on plant growth and development and crop productivity...
  66. doi Expression of OsDREB2A transcription factor confers enhanced dehydration and salt stress tolerance in rice (Oryza sativa L.)
    Garladinne Mallikarjuna
    Plant Molecular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi, India
    Biotechnol Lett 33:1689-97. 2011
    ..The ectopic overexpression of Dehydration-Responsive Element Binding transcription factors (DREBs) either in homologous or in heterologous plants ..
  67. pmc The physiology and proteomics of drought tolerance in maize: early stomatal closure as a cause of lower tolerance to short-term dehydration?
    Monika Benesova
    Department of Genetics and Microbiology, Faculty of Science, Charles University in Prague, Prague, Czech Republic
    PLoS ONE 7:e38017. 2012
    ..In our study, two maize (Zea mays L.) genotypes with contrasting sensitivity to dehydration were subjected to moderate drought conditions...
  68. ncbi Dehydration markedly impairs cardiovascular function in hyperthermic endurance athletes during exercise
    J Gonzalez-Alonso
    Department of Kinesiology and Health Education, The University of Texas at Austin, 78712, USA
    J Appl Physiol (1985) 82:1229-36. 1997
    We identified the cardiovascular stress encountered by superimposing dehydration on hyperthermia during exercise in the heat and the mechanisms contributing to the dehydration-mediated stroke volume (SV) reduction...
  69. pmc Hydraulic failure defines the recovery and point of death in water-stressed conifers
    Tim J Brodribb
    University of Tasmania, Hobart, Tasmania 7001, Australia
    Plant Physiol 149:575-84. 2009
    ..Maximum recoverable water stress (Psimin) corresponded to a 95% loss of Kleaf. Thus, we conclude that xylem hydraulics represents a direct limit to the drought tolerance of these conifer species...
  70. ncbi Differential regulation of transcript accumulation and alternative splicing of a DREB2 homolog under abiotic stress conditions in common wheat
    Chikako Egawa
    Laboratory of Plant Genetics, Department of Biological and Environmental Science, Faculty of Agriculture, and Graduate School of Science and Technology, Kobe University
    Genes Genet Syst 81:77-91. 2006
    ..of cold responsive (Cor)/late embryogenesis abundant (Lea) genes are induced by both low temperature (LT) and dehydration. To understand the molecular basis of cold acclimation and its relationship with drought stress response in ..
  71. pmc Transcriptional profiles of drought-responsive genes in modulating transcription signal transduction, and biochemical pathways in tomato
    Pengjuan Gong
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China
    J Exp Bot 61:3563-75. 2010
    ..The drought-responsive genes identified in this study could provide further information for understanding the mechanisms of drought tolerance in tomato...
  72. ncbi Safety of rapid intravenous rehydration and comparative efficacy of 3 oral rehydration solutions in the treatment of severely malnourished children with dehydrating cholera
    Nur H Alam
    Clinical Sciences Division, International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    J Pediatr Gastroenterol Nutr 48:318-27. 2009
    ..Assess the safety of rapid intravenous rehydration of severely malnourished children and compare the efficacy of 3 formulations of oral rehydration salts solutions...
  73. doi Dehydration: cause of fatigue or sign of pacing in elite soccer?
    Andrew M Edwards
    UCOL Institute of Technology, Faculty of Health Sciences, Palmerston North, New Zealand
    Sports Med 39:1-13. 2009
    Numerous studies have suggested that dehydration is a causal factor to fatigue across a range of sports such as soccer; however, empirical evidence is equivocal on this point...
  74. pmc Stress response in tardigrades: differential gene expression of molecular chaperones
    Andy Reuner
    Zoology, Biological Institute, Universitat Stuttgart, Pfaffenwaldring 57, 70569, Stuttgart, Germany
    Cell Stress Chaperones 15:423-30. 2010
    ..Because of the probable importance of stress proteins during the phases of dehydration and rehydration, the relative abundance of transcripts coding for two alpha-crystallin heat-shock proteins (Mt-..
  75. ncbi Markers of hydration status
    S M Shirreffs
    School of Sport and Exercise Sciences, Loughborough University, Leicestershire, UK
    Eur J Clin Nutr 57:S6-9. 2003
    ..The current evidence and opinion tend to favour urine indices, and in particular urine osmolality, as the most promising marker available...
  76. ncbi Two percent dehydration impairs and six percent carbohydrate drink improves boys basketball skills
    Kelly A Dougherty
    Noll Laboratory, Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802 6900, USA
    Med Sci Sports Exerc 38:1650-8. 2006
    To determine the effects of exercise heat-induced two percent dehydration (DEH) and euhydration (EUH) with a six percent carbohydrate-electrolyte solution (CES) compared with placebo EUH (P EUH) on basketball skills in skilled young ..
  77. ncbi Progressive dehydration causes a progressive decline in basketball skill performance
    Lindsay B Baker
    Noll Laboratory, Department of Kinesiology, Pennsylvania State University, University Park, PA 16802 6900, USA
    Med Sci Sports Exerc 39:1114-23. 2007
    To determine the effect of 1, 2, 3, and 4% dehydration (DEH) versus euhydration (EUH) on basketball performance in adult male players.
  78. ncbi Effects of fluid ingestion on cognitive function after heat stress or exercise-induced dehydration
    C Cian
    Centre de Recherches du Service de Sante des Armees, Unités de Psychologie et de Bioénergétique et Environnement, 38702 La Tronche Cedex, France
    Int J Psychophysiol 42:243-51. 2001
    This study investigated the effects of heat exposure, exercise-induced dehydration and fluid ingestion on cognitive performance...
  79. doi Over-expression of OsDREB genes lead to enhanced drought tolerance in rice
    Jian Qiang Chen
    College of Life Sciences, Beijing Normal University, Beijing, 100875, People s Republic of China
    Biotechnol Lett 30:2191-8. 2008
    ....
  80. doi Adaptive plasticity of killifish (Fundulus heteroclitus) embryos: dehydration-stimulated development and differential aquaporin-3 expression
    Angèle Tingaud-Sequeira
    Lab IRTA ICM, Passeig Maritim 37 49, 08003 Barcelona, Spain
    Am J Physiol Regul Integr Comp Physiol 296:R1041-52. 2009
    ..However, it is unknown if they are able to control development under dehydration conditions...
  81. ncbi Influence of age on thirst and fluid intake
    W L Kenney
    Noll Physiological Research Center and Schreyer Honors College, Penn State University, University Park, PA 16802, USA
    Med Sci Sports Exerc 33:1524-32. 2001
    ..Children rarely exhibit voluntary dehydration for activities lasting 45 min or less; however, drink flavoring and sodium chloride are important promoters of ..
  82. doi Physiology and proteomics of the water-deficit stress response in three contrasting peanut genotypes
    Kameswara Rao Kottapalli
    Department ofPlant and Soil Science, Texas Tech University, Lubbock, TX, USA
    Plant Cell Environ 32:380-407. 2009
    ..g. cell wall strengthening, signal transduction, energy metabolism, cellular detoxification and gene regulation) indicates that these molecules could affect the molecular mechanism of water-deficit stress tolerance in peanut...
  83. ncbi Cystic fibrosis: a disease of vulnerability to airway surface dehydration
    Richard C Boucher
    Cystic Fibrosis Pulmonary Research and Treatment Center and the UNC Virtual Lung Group, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
    Trends Mol Med 13:231-40. 2007
    ..Recent data suggest that CF lung disease pathogenesis reflects the vulnerability of airway surfaces to dehydration and collapse of mucus clearance...
  84. ncbi Airway surface dehydration in cystic fibrosis: pathogenesis and therapy
    Richard C Boucher
    Cystic Fibrosis Pulmonary Research and Treatment Center, University of North Carolina at Chapel Hill, North Carolina 27599, USA
    Annu Rev Med 58:157-70. 2007
    ..e., dehydration. CF ASL volume regulation depends on a single extracellular signaling system, ATP, which renders CF airways ..
  85. ncbi The Arabidopsis AtDi19 gene family encodes a novel type of Cys2/His2 zinc-finger protein implicated in ABA-independent dehydration, high-salinity stress and light signaling pathways
    Miguel A Rodriguez Milla
    Department of Biochemistry and Molecular Biology, University of Nevada, Reno, 89557 0014, USA
    Plant Mol Biol 61:13-30. 2006
    ..RT-PCR analyses showed that AtDi19-1 and AtDi19-3 steady-state transcript amounts were rapidly induced by dehydration, whereas transcript amounts for AtDi19-2 and AtDi19-4 increased in response to high-salt stress...
  86. pmc On the substrate specificity of dehydration by lacticin 481 synthetase
    Xingang Zhang
    Roger Adams Laboratory, Department of Chemistry, University of Illinois at Urbana Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA
    J Am Chem Soc 129:2212-3. 2007
  87. ncbi Differential responses of antioxidative system to chilling and drought in four rice cultivars differing in sensitivity
    Z Guo
    Biotechnology Laboratory for Turfgrass and Forages, College of Life Science, South China Agricultural University, Guangzhou 510642, China
    Plant Physiol Biochem 44:828-36. 2006
    ....
  88. doi An abscisic acid-related reduced transpiration promotes gradual embolism repair when grapevines are rehydrated after drought
    Claudio Lovisolo
    Dipartimento Colture Arboree, Universita di Torino, Via Leonardo da Vinci 44, I 10095 Grugliasco, Italy
    New Phytol 180:642-51. 2008
    ..mechanisms of embolism recovery are controversial for plants that are transpiring while undergoing cycles of dehydration and rehydration...
  89. ncbi Impaired cognitive function and mental performance in mild dehydration
    M M G Wilson
    Division of Geriatric Medicine, St Louis University Health Sciences Center, and GRECC, Veteran s Administration Medical Center, MO 63104, USA
    Eur J Clin Nutr 57:S24-9. 2003
    b>Dehydration is a reliable predictor of impaired cognitive status. Objective data, using tests of cortical function, support the deterioration of mental performance in mildly dehydrated younger adults...
  90. ncbi Induction of Hsp70 by desiccation, ionising radiation and heat-shock in the eutardigrade Richtersius coronifer
    K Ingemar Jönsson
    Department of Mathematics and Natural Science, Kristianstad University, S 291 88 Kristianstad, Sweden
    Comp Biochem Physiol B Biochem Mol Biol 146:456-60. 2007
    ....
  91. doi Genome structure of bdelloid rotifers: shaped by asexuality or desiccation?
    Eugene A Gladyshev
    Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, Woods Hole, MA 02543, USA
    J Hered 101:S85-93. 2010
    ....
  92. ncbi Adult blood pressure and climate conditions in infancy: a test of the hypothesis that dehydration in infancy is associated with higher adult blood pressure
    Debbie A Lawlor
    Department of Social Medicine, University of Bristol, Bristol, UK
    Am J Epidemiol 163:608-14. 2006
    ..the hottest and driest summers during infancy would be more likely to have suffered severe infant diarrhea and dehydration, and consequently have had higher blood pressure in adulthood, than those who experienced cooler and wetter ..
  93. ncbi Chronic dehydration may impair renal function in patients with chronic intestinal failure on long-term parenteral nutrition
    Madeleine Lauverjat
    Centre Agréé de Nutrition Parentérale à Domicile, Hopital E Herriot, 69437 Lyon, France
    Clin Nutr 25:75-81. 2006
    ..However, the aetiologies have remained elusive. The aim of this study was to evaluate the impact of parenteral nutrition, digestive status, and hydration level on renal function in LTPN patients...
  94. doi [Identification and characterization of "rd22" dehydration responsive gene in grapevine (Vitis vinifera L.)]
    Mohsen Hanana
    Laboratoire de Physiologie Moléculaire de la Vigne, CBBC, Hammam Lif, Tunisia
    C R Biol 331:569-78. 2008
    ..The latter, named Vvrd22, is a dehydration-responsive gene that is usually induced by the application of exogenous ABA...
  95. doi Protection of total body water content and absence of hyperthermia despite 2% body mass loss ('voluntary dehydration') in soldiers drinking ad libitum during prolonged exercise in cool environmental conditions
    Heinrich W Nolte
    ERGOnomics TECHnologies, PO Box 6264, Pretoria 0001, South Africa
    Br J Sports Med 45:1106-12. 2011
    ..The finding that TBW was protected by ad libitum drinking despite approximately 2% body mass loss suggests that the concept of 'voluntary dehydration' may require revision.
  96. doi Dark induction of the photoprotective xanthophyll cycle in response to dehydration
    Beatriz Fernández-Marín
    Departamento de Biología Vegetal y Ecología, Universidad del Pais Vasco, Bilbao, Spain
    J Plant Physiol 166:1734-44. 2009
    Some plants tolerate tissue dehydration. Dehydration conditions suppress photosynthesis, exacerbating photooxidative stress. In this study, fern samples were collected from the field, desiccated in darkness, and subsequently re-watered...
  97. ncbi The use of body mass changes as a practical measure of dehydration in team sports
    Gemma Harvey
    Department of Exercise Science and Sport Management, Australia
    J Sci Med Sport 11:600-3. 2008
    ..games of soccer to determine which of these methods was the most practical in a field setting for monitoring dehydration. Members (n=13) of a premiership soccer team with a mean age of 22.6 (+/-4.9) years old, height of 177.8 (+/-7...
  98. ncbi Does dehydration affect thickness of the pyloric muscle? An experimental study
    Ruth Starinsky
    Department of Radiology, Assaf Harofeh Medical Center, Zerifin 70300, Israel
    Ultrasound Med Biol 28:421-3. 2002
    ..05). Based on our preliminary results, we suggest that children with suspected CHPS should be well hydrated before the ultrasound (US) examination is performed, to avoid false-negative results and a consequent delay in treatment...
  99. ncbi Osmotic and metabolic responses to dehydration and urea-loading in a dormant, terrestrially hibernating frog
    Timothy J Muir
    Department of Zoology, Miami University, Oxford, OH 45056, USA
    J Comp Physiol B 177:917-26. 2007
    Physiological responses to dehydration in amphibians are reasonably well documented, although little work has addressed this problem in hibernating animals...
  100. ncbi Influence of diuretic-induced dehydration on competitive sprint and power performance
    Greig Watson
    The University of Connecticut, Human Performance Laboratory, Department of Kinesiology, Storrs, CT 06269 1110, USA
    Med Sci Sports Exerc 37:1168-74. 2005
    Diuretic-induced dehydration impairs prolonged running performance (> 1500 m). Sprinting performance may suffer by similar mechanisms (i.e...
  101. ncbi Survival of water stress in annual fish embryos: dehydration avoidance and egg envelope amyloid fibers
    J E Podrabsky
    Section of Integrative Physiology and Neurobiology, Department of Environmental, Population, and Organismic Biology, University of Colorado, Boulder 80309 0334, USA
    Am J Physiol Regul Integr Comp Physiol 280:R123-31. 2001
    ..No dehydration of the embryonic tissue is indicated based on microscopic observations and the retention of bulk (freezable) ..

Research Grants78

  1. SCCOR in Host Factors in Chronic Lung Disease
    Richard Boucher; Fiscal Year: 2007
    ..of the normal and cigarette smoke-exposed lung to mimics of aspects of COPD/CF disease; Project V: Mucus Dehydration and Evolution of COPD Lung Disease (R...
  2. Mechanisms of Endothelin 1-Induced Sickle Cell Pathology
    Alicia Rivera; Fiscal Year: 2009
    ..Erythrocyte dehydration, a hallmark in SCD, is in part mediated by activation of the K/Cl cotransporter, Gardos channel, and Na+/Mg2+ ..
  3. Mechanisms of Endothelin 1-Induced Sickle Cell Pathology
    Alicia Rivera; Fiscal Year: 2010
    ..Erythrocyte dehydration, a hallmark in SCD, is in part mediated by activation of the K/Cl cotransporter, Gardos channel, and Na+/Mg2+ ..
  4. Mechanisms of Endothelin 1-Induced Sickle Cell Pathology
    Alicia Rivera; Fiscal Year: 2009
    ..Erythrocyte dehydration, a hallmark in SCD, is in part mediated by activation of the K/Cl cotransporter, Gardos channel, and Na+/Mg2+ ..
  5. LISTERIA AND SHIGELLA USE ACTIN TO SPREAD CELL TO CELL
    Frederick Southwick; Fiscal Year: 2010
    ..causes bacteremia and meningitis, while the gram negative bacillus Shigella flexneri causes severe diarrhea and dehydration. The pathogenesis of Listeriosis and Shigellosis absolutely requires these intracellular bacteria to usurp the ..
  6. Long Term Outcomes in ICU Patients: Delirium & Apolipoprotein E
    Sheila Alexander; Fiscal Year: 2009
    ..increasing age, metabolic disturbances, electrolyte imbalances, drug (alcohol withdrawal, infection, seizures, dehydration, hyperthermia, head trauma, vascular disorders, intracranial space occupying lesions and others...
  7. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 1999
    ..The goal of this project is to determine critical efficacy and fetal safety issues central to maternal DDAVP treatment, prior to widespread clinical use in human pregnancies with oligohydramnios. ..
  8. MATERNAL DEHYDRATION--FETAL/AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 2002
    ..The goal of this project is to determine critical efficacy and fetal safety issues central to maternal DDAVP treatment, prior to widespread clinical use in human pregnancies with oligohydramnios. ..
  9. LISTERIA AND SHIGELLA USE HOST CELL ACTIN
    Frederick Southwick; Fiscal Year: 2006
    ..meningitis while the gram-negative bacillus Shigella flexneri infects normal hosts causing severe diarrhea and dehydration. The pathogenesis of Listeriosis and Shigellosis absolutely requires these intracellular bacteria to usurp the ..
  10. ACETAMINOPHEN VS IBUPROFEN ON RENAL FUNCTION DURING EXERCISE
    W Kenney; Fiscal Year: 1999
    ..Exercise, salt restriction, and/or dehydration cause transient reductions in renal functions that may be buffered by vasodilatory prostoglandins (PGs)...
  11. Tongue-pressure timing for liquid flow detection and control in swallowing
    CATRIONA MARGARET STEELE; Fiscal Year: 2010
    ..Dysphagia puts individuals at risk for malnutrition, dehydration and pneumonia and adversely affects quality of life...
  12. Mechanisms of Oxidative Stress and Inflammation during Prolonged Fasting and Slee
    Rudy M Ortiz; Fiscal Year: 2010
    ..protracted periods of absolute food and water deprivation for up to 3 months without exhibiting any indices of dehydration or electrolyte imbalances...
  13. HEPTOCELLULAR RESPONCE TO CRYOPRESERVATION
    Mehmet Toner; Fiscal Year: 2002
    ..g., DMSO). However, the disaccharide trehalose is known to stabilize many anhydrobiotic organisms against dehydration and desiccation stresses...
  14. Mechanisms of Oxidative Stress and Inflammation during Prolonged Fasting and Slee
    Rudy Ortiz; Fiscal Year: 2009
    ..protracted periods of absolute food and water deprivation for up to 3 months without exhibiting any indices of dehydration or electrolyte imbalances...
  15. Mechanisms of Oxidative Stress and Inflammation during Prolonged Fasting and Slee
    Rudy M Ortiz; Fiscal Year: 2010
    ..protracted periods of absolute food and water deprivation for up to 3 months without exhibiting any indices of dehydration or electrolyte imbalances...
  16. Mechanism of CTIP2 action in mouse epidermal homeostasis and barrier formation,
    ARUP K INDRA; Fiscal Year: 2010
    ..problem in the majority of premature infants, results in increased transepidermal water loss with concomitant dehydration and electrolyte imbalance, as well as fragile skin...
  17. G PROTEIN REGULATION OF CL SECRETION IN AIRWAY EPITHELIA
    BRUCE STANTON; Fiscal Year: 1993
    ..CFTR) secretion and the increased rate of Na reabsorption in the airway of patients with CF contributes to the dehydration of the airway and to the pathogenesis of lung disease...
  18. PATHOBIOCHEMISTRY OF CHLAMYDIA TRACHOMONAS HUMAN SEXUALLY TRANSMITTED DISEASES
    BIBHUTI SINGH; Fiscal Year: 2001
    ..and D were constituents of the synthetase complex and to define conditions and cofactors for the cyclization, dehydration and desaturation that underlie each enzymatic posttranslational conversion of gly-ser and gly-cys dipeptide ..
  19. OSMOLYTE PROTECTION OF PROTEINS AGAINST INACTIVATION
    DAVID BOLEN; Fiscal Year: 2001
    To adapt to harsh environmental stresses such as extremes of temperature, dehydration, and high osmotic pressure, certain organisms have accumulated intracellular concentrations of solutes called osmolytes ...
  20. AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTION
    HARRY SAX; Fiscal Year: 2004
    Short bowel syndrome is a devastating clinical condition which leads to dehydration, muscle wasting, debilitation and death...
  21. MATERNAL DEHYDRATION--FETAL & AMNIOTIC FLUID HOMEOSTASIS
    Michael Ross; Fiscal Year: 1992
    ..Although fetal plasma is dependent on maternal osm the impact of maternal dehydration and subsequent rehydration on the fetus has not been explored...
  22. ERYTHROCYTE MEMBRANE ABNORMALITIES IN SICKLE DISEASE
    Robert Hebbel; Fiscal Year: 1993
    ..hypothesis that vasopressin effects on endothelium explain the precipitation of vasocclusive crisis by clinical dehydration. Second, we will determine whether the several identified mechanisms leading to abnormal RBC/endothelial ..