Research Topics
Genomes and Genes
| sudden infant deathSummarySummary: The abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. (Pediatr Pathol 1991 Sep-Oct;11(5):677-84) Top Publications
Research Grants
| Scientific Experts
|
Detail Information
Publications
Cytokine responses and sudden infant death syndrome: genetic, developmental, and environmental risk factorsC Caroline Blackwell
Faculty of Health, School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, John Hunter Hospital, Lookout Road, New Lambton, NSW 2300, Australia
J Leukoc Biol 78:1242-54. 2005Despite the success of the campaigns to reduce the risk of sudden infant death syndrome (SIDS), it still remains the major cause of postneonatal mortality...
The frequency of molecular detection of virulence genes encoding cytolysin A, high-pathogenicity island and cytolethal distending toxin of Escherichia coli in cases of sudden infant death syndrome does not differ from that in other infant deaths and healtAmanda R Highet
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide, South Australia, Australia
J Med Microbiol 58:285-9. 2009Consistent pathological findings in sudden infant death syndrome (SIDS) are seen which display similarities to the pathogenesis of toxaemic shock and/or sepsis...- Clinical correlates, natural history and outcome of neonatal apnoeaTerry M Baird
Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
Semin Neonatol 9:205-11. 2004..Infants who have apnoea in the newborn period are thought not to be at higher risk for sudden infant death syndrome (SIDS)... - Review of risk factors for sudden infant death syndromeF M Sullivan
Division of Pharmacology and Toxicology, United Medical School, University of London, UK
Paediatr Perinat Epidemiol 15:144-200. 2001b>Sudden infant death syndrome (SIDS) accounts for the largest number of deaths during the first year of life in developed countries... - Intrathoracic petechial hemorrhages in sudden infant death syndrome and other infant deaths: time for re-examinationPaul N Goldwater
Microbiology and Infectious Diseases Department, The Women s and Children s Hospital, Discipline of Paediatrics, Children, Youth and Women s Health Service, North Adelaide, South Australia 5006, Australia
Pediatr Dev Pathol 11:450-5. 2008..pathogenesis of intrathoracic petechial hemorrhages through a retrospective autopsy report review of 174 sudden infant death syndrome (SIDS) cases (2004 definition) and 67 age-matched comparison deaths... - SIDS: past, present and futureEdwin A Mitchell
Department of Paediatrics, University of Auckland, Auckland, New Zealand
Acta Paediatr 98:1712-9. 2009..Conclusion: SIDS is preventable. Application of what we currently know could eliminate SIDS. The challenge is to find ways of implementing our knowledge... - The triple risk hypotheses in sudden infant death syndromeWarren G Guntheroth
Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98195 6320, USA
Pediatrics 110:e64. 2002b>Sudden infant death syndrome (SIDS) victims were regarded as normal as a matter of definition (Beckwith 1970) until 1952 when Kinney and colleagues argued for elimination of the clause, "unexpected by history... - Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDSR Ramanathan
Department of Pediatrics, Yale Medical School, Box 208064, New Haven, CT 06520-8064, USA
JAMA 285:2199-207. 2001..monitors designed to identify cardiorespiratory events are frequently used in infants at increased risk for sudden infant death syndrome (SIDS), but the efficacy of such devices for this use is unproven... - A review of the anatomy of the upper airway in early infancy and its possible relevance to SIDSS L Tonkin
New Zealand Cot Death Association, New Zealand
Early Hum Dev 66:107-21. 2002..months of life has been publicised, there has been a dramatic and consistent reduction in the incidence of sudden infant death syndrome (SIDS)... - Why babies should never sleep alone: a review of the co-sleeping controversy in relation to SIDS, bedsharing and breast feedingJames J McKenna
University of Notre Dame, Notre Dame, Indiana, IN 46556, USA
Paediatr Respir Rev 6:134-52. 2005.... - Incongruent cerebral growth in sudden infant death syndromeHazim Kadhim
Anatomic Pathology Service, Brugmann University Hospital, Brussels, Belgium
J Child Neurol 20:244-6. 2005b>Sudden infant death syndrome remains a leading cause of post-neonatal mortality in developed countries. Its etiopathogenic mechanisms are unknown... - Elevated serum concentrations of beta-tryptase, but not alpha-tryptase, in Sudden Infant Death Syndrome (SIDS). An investigation of anaphylactic mechanismsM G Buckley
Immunopharmacology Group, Southampton General Hospital, Southampton, UK
Clin Exp Allergy 31:1696-704. 2001BACKGROUND: Sudden Infant Death Syndrome, (SIDS) or cot death, remains the most common category of post-perinatal death in the UK... 
Recommendations for sudden infant death syndrome prevention: a discussion documentE A Mitchell
Department of Paediatrics, University of Auckland, Private Bag 92019, Auckland, New Zealand
Arch Dis Child 92:155-9. 2007This article reviews the evidence for the current UK Department of Health recommendations for prevention of sudden infant death syndrome (SIDS) and suggests other factors that should be considered...- Sterile site infection at autopsy in sudden unexpected deaths in infancyP N Goldwater
The Women s and Children s Hospital, and The University of Adelaide Discipline of Paediatrics, Children, Youth and Women s Health Service, 72 King William Road, North Adelaide, South Australia 5006, Australia
Arch Dis Child 94:303-7. 2009..To examine and compare bacteriological findings at autopsy of cases of sudden unexpected infant death and those of deaths from other cause... - Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant deathG Ottaviani
Institute of Pathology, Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and SIDS, University of Milan, Italy
J Clin Pathol 59:497-500. 2006..Her sudden death offered a unique insight into the possible role of delayed neuronal maturation and hypoplasia of the hypoglossal nucleus in representing a likely morphological substrate of sudden death... - Prone versus supine sleep position: a review of the physiological studies in SIDS researchB C Galland
Department of Women s and Children s Health, Otago Medical School, Dunedin, New Zealand
J Paediatr Child Health 38:332-8. 2002..studies, published over the last 10 years, have investigated the links between prone sleeping and sudden infant death syndrome (SIDS)... - The role of bacterial toxins in sudden infant death syndrome (SIDS)C C Blackwell
Department of Medical Microbiology, University of Edinburgh, Scotland, UK
Int J Med Microbiol 291:561-70. 2002There is increasing evidence for the involvement of bacterial toxins in some cases of sudden infant death syndrome (SIDS), particularly the pyrogenic toxins of Staphylococcus aureus... - Sudden infant death syndrome: no increased risk after immunisationM M T Vennemann
Institute of Legal Medicine, University of Munster, and Children s Hospital, University of Magdeburg, Germany
Vaccine 25:336-40. 2007.... - Sudden infant death syndrome (SIDS) shortly after hexavalent vaccination: another pathology in suspected SIDS?Giulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda 19, Milan 20122, Italy
Virchows Arch 448:100-4. 2006..Participants included pathologists with experience in the field of vaccines and sudden infant death syndrome who conducted autopsies... - Prevalence of congenital adrenal hyperplasia among sudden infant death in the Czech Republic and AustriaKristina A Strnadová
Department of Pediatrics, 3rd Faculty of Medicine, Charles University, CZ 100 81, Prague, Czech Republic
Eur J Pediatr 166:1-4. 2007..Hence, newborn screening would have prevented these deaths had it been available. In addition, we have shown that the I2 point mutation that is expected to lead to simple virilizing form may lead to a fatal outcome... - Sudden infant death syndrome--a defect in circulatory control?T Matthews
University College Dublin, Department of Paediatrics, Temple Street Children s Hospital and The Rotunda Hospital, Dublin, Ireland
Child Care Health Dev 28:41-3. 2002The majority of Sudden Infant Death Syndrome (SIDS) infants die during sleep and especially during the overnight sleep period... - Unexplained sudden death, including sudden infant death syndrome (SIDS), in the first and second years of life: case definition and guidelines for collection, analysis, and presentation of immunization safety dataGerhard Jorch
University of Magdeburg, Magdeburg, Germany
Vaccine 25:5707-16. 2007 - The role of respiratory control disorders in SIDSBradley T Thach
Department of Pediatrics, Washington University School of Medicine, 660 S Euclid, Campus Box 8208, St Louis, MO 63110, USA
Respir Physiol Neurobiol 149:343-53. 2005..In drawing conclusions it is well to recognize that mechanisms leading to death in SIDS are heterogeneous and therefore there is room for several plausible theories for respiratory or circulatory abnormalities contributing to SIDS... - Sudden infant death syndrome: a critical review of approaches to researchP N Goldwater
Microbiology and Infectious Diseases Department, The Women s and Children s Hospital, North Adelaide, South Australia 5006
Arch Dis Child 88:1095-100. 2003..Close examination of the pathological clues would provide better insights into the mechanisms underlying this enigmatic and heartbreaking problem... - Small for gestational age infants and sudden infant death syndrome: a confluence of complex conditionsCarl E Hunt
Chevy Chase, Maryland 20815, USA
Arch Dis Child Fetal Neonatal Ed 92:F428-9. 2007 - Changing conclusions on secondhand smoke in a sudden infant death syndrome review funded by the tobacco industryElisa K Tong
Division of General Internal Medicine Fellowship Program, Cardiovascular Research Institute, University of California, San Francisco, California 94143-1390, USA
Pediatrics 115:e356-66. 2005..Secondhand smoke (SHS) has been linked causally with sudden infant death syndrome (SIDS) in major health reports... - Population trends in sudden infant death syndromeAnne Louise Ponsonby
National Centre for Epidemiology and Population Health, Australian National University, ACT
Semin Perinatol 26:296-305. 2002This review documents and assesses recent trends in sudden infant death syndrome. We review medical literature, Internet resources, and national governmental data... - Heart weight in infants--a comparison between sudden infant death syndrome and other causes of deathP Råsten-Almqvist
Department of Forensic Medicine, Karolinska Institute, Stockholm, Sweden
Acta Paediatr 89:1062-7. 2000..1998, out of 468 infants autopsied at the Department of Forensic Medicine in Stockholm, Sweden, 331 died of sudden infant death syndrome (SIDS), while 137 died of other causes... - Critical diaphragm failure in sudden infant death syndromePontus Max Axel Siren
JGK Memorial Research Library, Snellmanin k 15, 00170, Helsinki, Finland
Ups J Med Sci 116:115-23. 2011b>Sudden infant death syndrome (SIDS) is the leading cause of death in infants between the ages of 1 and 12 months in developed countries. SIDS is by definition a diagnosis of exclusion, and its mechanism of action is unknown... - Laryngeal basement membrane thickening is not a reliable postmortem marker for SIDS: results from the Chicago Infant Mortality StudyH F Krous
Children s Hospital San Diego, California 92123, USA
Am J Forensic Med Pathol 20:221-7. 1999..been suggested that laryngeal basement membrane (LBM) thickening is a pathognomonic postmortem marker for sudden infant death syndrome (SIDS) and is not seen in other causes of explained sudden infant death... - Short-term rhythms of the cardiorespiratory system and their significance in neonatologyA Patzak
Institute of Physiology, Humboldt University of Berlin, University Hospital Charite, Germany
Chronobiol Int 16:249-68. 1999..The results of studies on infants at risk (for example, for sudden infant death), with the help of statistical and spectral analysis of time series to obtain new indices, have proved to .. - Sudden infant death syndrome, bedsharing, parental weight, and age at deathC Carroll-Pankhurst
Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio 44106 4945, USA
Pediatrics 107:530-6. 2001To assess the role of parental bedsharing in sudden infant death syndrome (SIDS)-like deaths, this study examines the hypothesis that, compared with other SIDS cases, the age distribution of deaths associated with bedsharing should be .. - What is the mechanism of sudden infant deaths associated with co-sleeping?Christine G McIntosh
Dept of Physiology, University of Auckland, Private Bag 92019, Auckland 1023, New Zealand
N Z Med J 122:69-75. 2009The risk of Sudden Infant Death Syndrome (SIDS) has fallen dramatically in the "Back to Sleep" era; however, half the cases now occur when the infant has been sleeping in bed with another person... - Extraintestinal Escherichia coli isolations from SIDS cases and other cases of sudden death in Victoria, AustraliaJ L Pearce
Department of Agricultural Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora, Melbourne, Australia
FEMS Immunol Med Microbiol 25:137-44. 1999..This investigation is an extension of previous studies on the possible role of intestinal Escherichia coli in sudden infant death syndrome (SIDS) to include the isolation of extraintestinal E. coli... - Sudden infant death syndrome: what questions should we ask?J L Pearce
School of Agricultural Sciences, La Trobe University, Bundoora, Vic, Australia
FEMS Immunol Med Microbiol 25:7-10. 1999A limited historical perspective can affect the questions we pose about the sudden infant death syndrome (SIDS) issue... - Concurrent risks in sudden infant death syndromeBarbara M Ostfeld
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Department of Pediatrics, PO Box 19, New Brunswick, NJ 08903, USA
Pediatrics 125:447-53. 2010Despite improved education on safe sleep, infants are still exposed to multiple risks for sudden infant death syndrome (SIDS)... - Interleukin-2 as a neuromodulator possibly implicated in the physiopathology of sudden infant death syndromeHazim Kadhim
Neuropathology Unit, Department of Anatomic Pathology, Centre Hospitalier Universitaire Brugmann, Universite Libre De Bruxelles U L B, Place Van Gehuchten 4, 1020 Brussels, Belgium
Neurosci Lett 480:122-6. 2010..centers, including those controlling cardiorespiratory- and sleep/arousal pathophysiology, is reported in sudden infant death syndrome (SIDS). Biological mechanisms underlying SIDS, however, remain unclear... - Gene variants predisposing to SIDS: current knowledgeSiri H Opdal
Institute of Forensic Medicine, University of Oslo, Oslo, Norway
Forensic Sci Med Pathol 7:26-36. 2011..A dehydrogenase deficiency and cardiac arrest due to long QT syndrome, or as predisposing factors for sudden infant death syndrome (SIDS)... - Anatomic changes related to laryngeal descent from birth to 1 year of age: do they play a role in SIDS?Robert E Stephens
Department of Anatomy, Kansas City Mo University of Medicine and Biosciences, 1750 Independence Ave, Kansas City, MO 64106, USA
Ear Nose Throat J 89:313-7. 2010..if there is any correlation between the associated anatomic changes and the timing of the peak incidence of sudden infant death syndrome (SIDS), which is 2 to 4 months of age... - Rebreathing of exhaled gases: importance as a mechanism for the causal association between prone sleep and sudden infant death syndromeJ S Kemp
Division of Pulmonary Medicine, St. Louis Children's Hospital, St. Louis, Missouri 63110, USA
Sleep 19:S263-6. 1996Twenty to 52% of sudden infant death syndrome (SIDS) victims are found dead with their noses and mouths turned into underlying bedding... - Staphylococcal enterotoxin genes are common in Staphylococcus aureus intestinal flora in Sudden Infant Death Syndrome (SIDS) and live comparison infantsAmanda R Highet
Department of Microbiology and Infectious Diseases, SA Pathology at the Women s and Children s Hospital, North Adelaide, SA, Australia
FEMS Immunol Med Microbiol 57:151-5. 2009Pathological and epidemiological findings in sudden infant death syndrome (SIDS) suggest an infectious aetiology with indications of involvement of staphylococcal enterotoxins (SEs)... - Organ weights in cases of sudden infant death syndrome: a German studyTony Fracasso
Institute of Legal Medicine, University of Munster, Germany
Am J Forensic Med Pathol 30:231-4. 2009Despite its decreasing incidence, sudden infant death syndrome (SIDS) still remains an important cause of death in infancy. Since Felix Platter described the case of a child suffocated because of a massive goiter (Platter E... - Birth weight- and gestational age-specific sudden infant death syndrome mortality: United States, 1991 versus 1995M H Malloy
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas 77555 0526, USA
Pediatrics 105:1227-31. 2000To estimate the changes in birth weight- and gestational age-specific sudden infant death syndrome (SIDS) mortality rates since the publication of the sleep-positioning recommendations by the American Academy of Pediatrics Task Force on .. - Immunohistochemical and molecular-pathological diagnosis of myocarditis in cases of suspected sudden infant death syndrome (SIDS)--a multicenter studyReinhard Dettmeyer
Institute of Forensic Medicine, University of Giessen, Frankfurter Street 58, D 35392 Giessen, Germany
Leg Med (Tokyo) 11:S124-7. 2009..Preliminary criteria for cellular immunohistochemical diagnosis of viral myocardial affections derived from these findings were suggested... - Myocardial inflammation, cellular death, and viral detection in sudden infant death caused by SIDS, suffocation, or myocarditisHenry F Krous
Department of Pathology, University of California San Diego, La Jolla, CA 92037, USA
Pediatr Res 66:17-21. 2009..Very mild myocardial lymphocyte and macrophage infiltration and scattered necrotic cardiomyocytes in SIDS are not pathologic, but may occur after the developing heart is exposed to environmental pathogens, including viruses... - Intrathoracic petechiae in SIDS: a retrospective population-based 15-year studyHenry F Krous
Rady Children s Hospital San Diego, 3020 Children s Way, M5007, San Diego, CA 92123, USA
Forensic Sci Med Pathol 4:234-9. 2008Intrathoracic petechiae (IP), the most common gross finding in sudden infant death syndrome (SIDS) cases at autopsy, suggest upper airway obstruction (UAO) occurs during the terminal event... - Novel hypothesis for unexplained sudden unexpected death in infancy (SUDI)A R Highet
Department of Microbiology and Infectious Diseases, SA Pathology, Women s and Children s Hospital, North Adelaide, South Australia, Australia
Arch Dis Child 94:841-3. 2009..The objective was to assess these observations in the context of the pathology and epidemiology of sudden infant death syndrome (SIDS) in relation to the role of infection and inflammation as triggers of these deaths. - Sleep influences on homeostatic functions: implications for sudden infant death syndromeR M Harper
Department of Neurobiology, The Brain Research Institute, University of California at LA, Los Angeles, CA, USA
Respir Physiol 119:123-32. 2000The mechanisms underlying the sudden infant death syndrome (SIDS) appear to have origins in the fetal environment resulting in neural damage which later compromises responses to breathing or blood pressure challenges during sleep... - A prospective study of smoking during pregnancy and SIDSK Wisborg
Perinatal Epidemiological Research Unit, Department of Gynaecology and Obstetrics, Aarhus University Hospital, DK 8200 Aarhus N, Denmark
Arch Dis Child 83:203-6. 2000To study the association between smoking during pregnancy and sudden infant death syndrome (SIDS) using prospectively collected data, making it possible to account for a number of potential confounders. - Serotypes of Escherichia coli in sudden infant death syndromeJ L Pearce
Department of Agricultural Sciences, La Trobe University, Melbourne, Vic, Australia
J Appl Microbiol 108:731-5. 2010To examine the diversity of Escherichia coli serotypes found in the intestinal contents of infants who died of Sudden Infant Death Syndrome (SIDS) compared with that in comparison infants. - Effects of the supine and prone position on diaphragm thickness in healthy term infantsV K Rehan
Department of Pediatrics, Memorial Hospital of Rhode Island, Pawtucket, Rhode Island, USA
Arch Dis Child 83:234-8. 2000The physiological basis underlying the decline in the incidence of sudden infant death syndrome (SIDS) associated with changing the sleep position from prone to supine remains unknown. - Cardiomyopathic and channelopathic causes of sudden unexplained death in infants and childrenDavid J Tester
Departments of Medicine, Pediatrics, and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota 55905, USA
Annu Rev Med 60:69-84. 2009..a critical analysis of the current spectrum and prevalence of channelopathies as the pathogenic basis for sudden infant death syndrome (SIDS), and provide a brief synopsis on genetic testing for such potentially lethal cardiac .. - Multiple serotonergic brainstem abnormalities in sudden infant death syndromeDavid S Paterson
Department of Pathology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
JAMA 296:2124-32. 2006..Previously, abnormalities in 5-HT receptor binding in the medullae of infants dying from sudden infant death syndrome (SIDS) were identified, suggesting that medullary 5-HT dysfunction may be responsible for a subset .. - Association of the serotonin transporter gene with sudden infant death syndrome: a haplotype analysisDebra E Weese-Mayer
Department of Pediatrics, Rush Children s Hospital at Rush Presbyterian St Luke s Medical Center, Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA
Am J Med Genet A 122:238-45. 2003..raphé obscurus, and other medullary regions is decreased in sudden infant death syndrome (SIDS) cases... - Ethnicity, infection and sudden infant death syndromeC Caroline Blackwell
Immunology and Microbiology, Faculty of Health, David Maddison Building, School of Biomedical Sciences, University of Newcastle, and Hunter Medical Research Institute, Newcastle, NSW 2300, Australia
FEMS Immunol Med Microbiol 42:53-65. 2004.... - Impaired cardiac function during postnatal hypoxia in rats exposed to nicotine prenatally: implications for perinatal morbidity and mortality, and for sudden infant death syndromeT A Slotkin
Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA
Teratology 55:177-84. 1997..Our results also indicate the need to test adverse effects of fetal drug exposure using conditions that challenge any given physiological system rather than relying solely on changes under basal conditions... - Recent trend of the incidence of sudden infant death syndrome in JapanToshiko Sawaguchi
Department of Legal Medicine, Faculty of Medicine, Tokyo Women s Medical University, 8 1 Kawada cho, Shinjuku, Tokyo 162 8666, Japan
Early Hum Dev 75:S175-9. 2003..To clarify the trend of the incidence of SIDS in the last 20 years in Japan to provide the basis for health administration training... - The sudden infant death syndrome gene: does it exist?Siri H Opdal
Institute of Forensic Medicine, University of Oslo, Rikshospitalet University Hospital, Oslo, Norway
Pediatrics 114:e506-12. 2004BACKGROUND: Sudden infant death syndrome (SIDS) is in a difficult position between the legal and medical systems... - Guidelines for neuropathologic diagnostics of perinatal unexpected loss and sudden infant death syndrome (SIDS): a technical protocolLuigi Matturri
Institute of Pathology, University of Milan, Via della Commenda, Milan, Italy
Virchows Arch 452:19-25. 2008..of the growing information on the pathophysiology and clinical aspects of unexpected perinatal loss and sudden infant death syndrome (SIDS), a novel approach to the inherent problems by pathologists has become necessary... - SIDS, ALTE, apnea, and the use of home monitorsPaula A Farrell
Department of Pediatrics, Section of Neonatal-Perinatal Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, IN, USA
Pediatr Rev 23:3-9. 2002 - Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American populationKevin G Broadbelt
Department of Pathology, Enders Building Room 1111, Children s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USA
Pediatr Res 66:631-5. 2009An important subset of the sudden infant death syndrome (SIDS) is associated with multiple serotonergic (5-HT) abnormalities in regions of the medulla oblongata... - A functional approach to sudden unexplained infant deathsTracey S Corey
Kentucky Office of the Chief Medical Examiner, Louisville, Kentucky 40204, USA
Am J Forensic Med Pathol 28:271-7. 2007..This text of this paper was officially approved and endorsed by the NAME board of directors on October 14, 2005, at the annual meeting in Los Angeles, CA... - Tummy time! Preventing unwanted effects of the "Back to Sleep" campaignLesa L K Chizawsky
Stollery Children's Hospital, Edmonton, Canada
AWHONN Lifelines 9:382-7. 2005 - Prevention of sudden infant death syndrome (SIDS) due to an active health monitoring system 20 years prior to the public "Back to Sleep" campaignsM Vennemann
Institute of Legal Medicine, University of Munster, Germany
Arch Dis Child 91:324-6. 2006Before reunification, the post-neonatal mortality rate was lower in East Germany than in West Germany. Moreover, the incidence of SIDS (sudden infant death syndrome) was much lower in the East. - Putting babies "back to sleep": can we do better?Linda J Levy Raydo
Children s Hospital, Albany Medical Center, NY 12208, USA
Neonatal Netw 24:9-16. 2005..Pediatrics first recommended in 1992 that infants be placed on their backs for sleep to reduce the risk for sudden infant death syndrome (SIDS)... - Heart rate variability and cardiac reflexes in small for gestational age infantsBarbara C Galland
Dept of Women s and Children s Health, Dunedin School of Medicine, Univ of Otago, PO Box 913, Dunedin, New Zealand
J Appl Physiol 100:933-9. 2006..The finding that the sympathetic component of the control of HRV was higher in SGA infants could link with findings in adulthood of an association between being born SGA and a higher risk of cardiovascular disease... - Maternal-infant bedsharing: risk factors for bedsharing in a population-based survey of new mothers and implications for SIDS risk reductionMartin B Lahr
Disability Determination Services, Oregon Department of Human Services, 3150 Lancaster Dr NE, Salem, OR 97305 1350, USA
Matern Child Health J 11:277-86. 2007..This information would be useful to inform public policy, to guide clinical practice and to help focus research. The objective was to explore the prevalence and determinants of bedsharing in Oregon... - [Bed sharing and sudden infant death]Arne Stray-Pedersen
Rettsmedisinsk institutt, Rikshospitalet, 0027 Oslo
Tidsskr Nor Laegeforen 125:2919-21. 2005The aim of the study was to investigate bed sharing as a risk factor for sudden infant death syndrome (SIDS). - Are the risk factors for SIDS different for preterm and term infants?J M D Thompson
Department of Paediatrics, University of Auckland, New Zealand
Arch Dis Child 91:107-11. 2006..Mortality from SIDS has declined since the recommendation that infants are not placed prone to sleep. SIDS mortality is higher in infants born preterm than those born at term... - Risk factors associated with sudden unexplained infant death: a prospective study of infant care practices in KentuckyLisa B E Shields
Office of the Chief Medical Examiner, Urban Government Center, 810 Barret Ave, Louisville, KY 40204, USA
Pediatrics 116:e13-20. 2005..14; 95% CI: 0.06-0.33). One infant succumbed to sudden infant death syndrome at 3 months of age, and another infant died suddenly and unexpectedly at 9 months of age... - Sudden infant death syndrome and sleeping position in pre-term and low birth weight infants: an opportunity for targeted interventionP S Blair
Institute of Child Life and Health, Department of Clinical Science, South Bristol, University of Bristol, UK
Arch Dis Child 91:101-6. 2006AIMS: To determine the combined effects of sudden infant death syndrome (SIDS) risk factors in the sleeping environment for infants who were "small at birth" (pre-term (<37 weeks), low birth weight (<2500 g), or both)... - [Epidemiology of 25 years of crib death (sudden infant death syndrome) in the Netherlands; incidence of crib death and prevalence of risk factors in 1980-2004]G A de Jonge
Centraal Bureau voor de Statistiek, Voorburg
Ned Tijdschr Geneeskd 149:1273-8. 2005OBJECTIVE: To describe the prevalence of risk factors and the incidence of cot death (sudden infant death syndrome; SIDS) in the Netherlands during the last 25 years. DESIGN: Descriptive... - [Sudden infant death syndrome: the times are changing]P L P Brand
Isala Klinieken, Amalia Kinderafdeling, Postbus 10 500, 8000 GM Zwolle
Ned Tijdschr Geneeskd 149:1254-6. 2005Case-control studies of sudden infant death syndrome (SIDS) in the Netherlands have shown a number of important risk factors, including prone sleeping position, the use of a duvet, the use of sedating antihistamines, and bed-sharing with .. - [Sleeping habits related to sudden infant death syndrome: a population-based study]Lorena Teresinha Consalter Geib
Universidade de Passo Fundo, Rua Tiradentes 400, Apto 601, Passo Fundo, RS 99010 260, Brazil
Cad Saude Publica 22:415-23. 2006This cross-sectional study on sleeping habits with potential risk for sudden infant death syndrome included all live births in Passo Fundo, Rio Grande do Sul, Brazil, in 2003 with data collection from Certificates of Live Birth and .. - Tummy time is importantJohn M Graham
Department of Clinical Genetics and Dysmorphology, Cedars-Sinai Medical Center, David Geffen School of Medicine at UCLA, 444 South San Vicente Boulevard #1001, Los Angeles, CA 90048, USA
Clin Pediatr (Phila) 45:119-21. 2006 - Separate sleep environment for infantsTeresa C Casey
J Obstet Gynecol Neonatal Nurs 36:362-3; author reply 363. 2007 - Bed-sharing in the first four months of life: a risk factor for sudden infant deathJan H Ruys
Leiden University Medical Center, Reviuslaan 38, 2343 JR Oegstgeest, The Netherlands
Acta Paediatr 96:1399-403. 2007To investigate the risk of sudden infant death in the Netherlands during bed-sharing in the first half year of life and the protective effect of breastfeeding on it. - Is SIDS on the rise??Lisa B E Shields
Office of the Associate Chief Medical Examiner, Frankfort, Kentucky, USA
J Ky Med Assoc 105:343-53. 2007b>Sudden Infant Death Syndrome (SIDS) is defined as a diagnosis of exclusion, after an evaluation of the medical history, complete postmortem examination, and scene investigation... - To co-sleep or not to sleep?Bernt Alm
Institute of Clinical Sciences, Department of Paediatrics, Gothenburg, Sweden
Acta Paediatr 96:1385-6. 2007 - Mother-infant cosleeping, breastfeeding and sudden infant death syndrome: what biological anthropology has discovered about normal infant sleep and pediatric sleep medicineJames J McKenna
Department of Anthropology and Mother Baby Behavioral Sleep Laboratory, University of Notre Dame, Notre Dame, IN 46556, USA
Am J Phys Anthropol . 2007.... - Neuronal cell death in the Sudden Infant Death Syndrome brainstem and associations with risk factorsRita Machaalani
Department of Medicine, Room 206, Blackburn Building, D06, The University of Sydney, NSW 2006, Australia
Brain 131:218-28. 2008..variations in the immunoreactive expression with development; (ii) comparison of infants diagnosed with the Sudden Infant Death Syndrome (SIDS, n = 67) to infants who died suddenly with another diagnosis (non-SIDS, n = 25); and (iii) .. - Bassinet use and sudden unexpected death in infancyJodi Pike
Pediatric Residency Program, Children s National Medical Center, Washington, DC 20010, USA
J Pediatr 153:509-12. 2008..To analyze risk factors in infants who die suddenly and unexpectedly in bassinets... - [Revised guideline 'prevention of cot death']T W H Flinsenberg
Maaslandziekenhuis, afd Kindergeneeskunde, Postbus 5500, 6130 MB Sittard
Ned Tijdschr Geneeskd 152:1370-5. 2008There are new insights into the pathogenesis of cot death ('sudden infant death syndrome'; SIDS)... - Economic antecedents of prone infant sleep placement among black mothersTim A Bruckner
Department of Epidemiology, School of Public Health, University of California at Berkeley, CA 94720 7360, USA
Ann Epidemiol 18:678-81. 2008Black infants die from sudden infant death syndrome at twice the incidence observed among non-Hispanic white infants. Explanations for this disparity include a two-fold greater prevalence of prone (i.e... - The state of South Dakota's child: 2006--Part II--safe sleepAnn L Wilson
South Dakota State University, USA
S D Med 60:55-9, 61. 2007b>Sudden Infant Death Syndrome (SIDS) has dramatically declined nationally and in South Dakota since the beginning of the "Back to Sleep Campaign" in 1994... - Aspiration of gastric contents in sudden infant death syndrome without cardiopulmonary resuscitationHenry F Krous
Department of Pathology, Rady Children s Hospital, San Diego, California 92123, USA
J Pediatr 150:241-6. 20071) To compare demographic profiles among sudden infant death syndrome (SIDS) infants with or without gastric aspiration, for whom cardiopulmonary resuscitation (CPR) had not been attempted; (2) to review the severity and potential .. - Commentary on: Alexander RT, Radisch D. Sudden infant death syndrome risk factors with regards to sleep position, sleep surface, and co-sleeping. J Forensic Sci 2005;50:1-5Martin B Lahr
J Forensic Sci 51:427; author reply 428-9. 2006 - [The influence of Sudden Infant Death Syndrome (SIDS) risk factors on health, growth and development in the first year of life. A preliminary report]Maciej Zakrzewski
Klinika Pediatrii, , , , 01-809 Warszawa, Poland
Med Wieku Rozwoj 9:763-71. 2005.... - Where should babies sleep?Sue Mace
Care of Next Infant, Chesterfield Royal Hospital NHS Foundation Trust
Community Pract 79:180-3. 2006An average of six babies die unexpectedly each week. Sudden infant death syndrome is the predominant cause but many deaths are recorded as unascertained... - Effect of "this side up" T-shirts on infant sleep positionDebora L Barnes Josiah
Office of Family Health, Nebraska Health and Human Services System, P O Box 95007, 301 Centennial Mall South, Lincoln, Nebraska 68509 5007, USA
Matern Child Health J 11:45-8. 2007..To assess the impact of "This Side Up" T-shirts on parental practices in Nebraska... - [Reducing the risk of sudden infant death syndrome through safe sleep practices]Chu-Yu Huang
Department of Nursign, Cedarville University, USA
Hu Li Za Zhi 53:11-6. 2006b>Sudden infant death syndrome (SIDS) is the unexplained sudden death of an infant under one year of age... - Sleep environment, positional, lifestyle, and demographic characteristics associated with bed sharing in sudden infant death syndrome cases: a population-based studyBarbara M Ostfeld
SIDS Center of New Jersey, Department of Pediatrics, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ 08903-0019, USA
Pediatrics 118:2051-9. 2006BACKGROUND: In 2005, the American Academy of Pediatrics Task Force on Sudden Infant Death Syndrome recommended that infants not bed share during sleep... - Asymmetric heads and failure to climb stairsJames S Kemp
J Pediatr 149:594-5. 2006 - Sudden infant death syndrome: risk factors for infants found face down differ from other SIDS casesJohn M D Thompson
Department of Pediatrics, University of Auckland, New Zealand
J Pediatr 149:630-633. 2006OBJECTIVE: To test the hypothesis that infants with sudden infant death syndrome (SIDS) found face down (FD) would have SIDS risk factors different from those found in other positions (non-face-down position, NFD)... - The controversy about what constitutes safe and nurturant infant sleep environmentsKatherine H Morgan
University of Tennessee College of Nursing, Knoxville, TN, USA
J Obstet Gynecol Neonatal Nurs 35:684-91. 2006..This article seeks to inform health care professionals of the issues involved in the controversy and to offer guidelines for educating parents about safe and unsafe sleep practices... - Infant sleeping arrangements and practices during the first year of lifeFern R Hauck
University of Virginia School of Medicine, Department of Family Medicine, PO Box 800729, Charlottesville, VA 22908 0729, USA
Pediatrics 122:S113-20. 2008..Our goal was to examine the sleeping arrangements for infants from birth to 1 year of age and to assess the association between such arrangements and maternal characteristics... - Determinants of infant sleep position in an urban populationRachel Y Moon
Department of General Pediatrics and Adolescent Medicine, Children's National Medical Center, Washington, DC 20010, USA
Clin Pediatr (Phila) 41:569-73. 2002..Improved educational efforts for parents of African-American newborns should continue to focus on encouraging supine positioning, smoke cessation, and other safe sleep practices... - Bedsharing and sudden infant death syndrome (SIDS) in Scotland, UKDavid Tappin
Lancet 363:994. 2004 - Effect of position on sleep, heart rate variability, and QT interval in preterm infants at 1 and 3 months' corrected ageRonald L Ariagno
Department of Pediatrics, Stanford University School of Medicine, Stanford, California, USA
Pediatrics 111:622-5. 2003Prone sleeping position has a strong link to sudden infant death syndrome (SIDS), and the "Back to Sleep" campaign has played an important role in reducing SIDS... - [Sudden infant death--prevention programs in Austria]Ursula Kiechl-Kohlendorfer
Abteilung für Neonatologie und neonatologische Intensivmedizin, Universitätsklinik für Kinder und Jugendheilkunde Innsbruck, Innsbruck, Osterreich
Wien Klin Wochenschr 115:881-6. 2003In the current study, design and success of intervention programmes to prevent sudden infant death syndrome (SIDS) in Austria are described and major future challenges indicated... - Infant sleeping position and the risk of sudden infant death syndrome in California, 1997-2000De Kun Li
Division of Research, Kaiser Foundation Research Institute, Kaiser Permanente, Oakland, CA 94612, USA
Am J Epidemiol 157:446-55. 2003To assess the association between infant sleeping position and risk of sudden infant death syndrome (SIDS) in an ethnically diverse US population, the authors conducted a population-based case-control study in 11 counties in California ..
Research Grants
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2009..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Neonatal Long QT Syndrome and Sudden Infant DeathAlfred L George; Fiscal Year: 2010..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2007..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Coordination of orofacial and respiratory movementsDetlef H Heck; Fiscal Year: 2010..in coordinating orofacial and respiratory movements are implicated in human health conditions such as sudden infant death syndrome (SIDS), swallowing dysfunction (dysphagia) and speech disorders (dysarthria)...
- Nicotine Modulation of Parasympathetic Cardiac NeuronsDavid Mendelowitz; Fiscal Year: 2009..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS). SIDS is the leading cause of death among infants who are 1 month to 1 year old...
- MECHANISM OF CARDIORESPIRATORY RHYTHM IN NEONATESDavid Mendelowitz; Fiscal Year: 2010..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS)...
- MECHANISM OF CARDIORESPIRATORY RHYTHM IN NEONATESDavid Mendelowitz; Fiscal Year: 2011..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS)...
- Developmental Genetics of Serotonin Neuron Subtypes in Brain Reward CircuitsSusan Dymecki; Fiscal Year: 2007..pathological anxiety, to childhood developmental disorders such as autism, fetal alcohol syndrome, and the sudden infant death syndrome. Each disorder differs in clinical feature, suggesting heterogeneity in serotonin neuron function...
- The upper airway and the Sudden Infant Death SyndromeDonald Bartlett; Fiscal Year: 2010The incidence of the Sudden Infant Death Syndrome (SIDS) has decreased substantially in the United States and elsewhere as a result of educational campaigns favoring the supine posture for sleeping infants...
- Mu Opioid Receptor Regulation in Neonatal BrainstemGEORGE OLSEN; Fiscal Year: 2006..These neonates exhibit withdrawal hyperventilation and an increased incidence of sudden infant death syndrome (SIDS)...
- Improving the Self-Efficacy of African American Parents in Infant Supine SleepKathryn L Moseley; Fiscal Year: 2010..African American infants also die of Sudden Infant Death Syndrome (SIDS) at rates 2-3 times greater than non-Hispanic White infants...
- Developmental defects in serotonin neurons and the response to O2 and CO2George Richerson; Fiscal Year: 2009b>Sudden infant death syndrome (SIDS) is the most common cause of post neonatal infant death in the U.S. The mechanisms are unknown, but abnormalities in the serotonin system have been consistently found in autopsy studies...
- Developmental defects in serotonin neurons and the response to O2 and CO2George Richerson; Fiscal Year: 2007b>Sudden infant death syndrome (SIDS) is the most common cause of post neonatal infant death in the U.S. The mechanisms are unknown, but abnormalities in the serotonin system have been consistently found in autopsy studies...