Genomes and Genes
sudden infant death
Summary: The abrupt and unexplained death of an apparently healthy infant under one year of age, remaining unexplained after a thorough case investigation, including performance of a complete autopsy, examination of the death scene, and review of the clinical history. (Pediatr Pathol 1991 Sep-Oct;11(5):677-84)
Publications279 found, 100 shown here
- Cytokine responses and sudden infant death syndrome: genetic, developmental, and environmental risk factorsC Caroline Blackwell
Faculty of Health, School of Biomedical Sciences, University of Newcastle and Hunter Medical Research Institute, John Hunter Hospital, Lookout Road, New Lambton, NSW 2300, Australia
J Leukoc Biol 78:1242-54. 2005Despite the success of the campaigns to reduce the risk of sudden infant death syndrome (SIDS), it still remains the major cause of postneonatal mortality...
- Prevalence of long-QT syndrome gene variants in sudden infant death syndromeMarianne Arnestad
Institute of Forensic Medicine, University of Oslo, Oslo, Norway
Circulation 115:361-7. 2007The hypothesis that some cases of sudden infant death syndrome (SIDS) could be caused by long-QT syndrome (LQTS) has been supported by molecular studies...
- Sudden infant death syndrome in mice with an inherited mutation in RyR2Nitin Mathur
Department of Molecular Physiology and Biophysics, Division of Cardiology, Baylor College of Medicine, Houston, TX 77030, USA
Circ Arrhythm Electrophysiol 2:677-85. 2009Mutations in the cardiac ryanodine receptor gene (RyR2) have been recently identified in victims of sudden infant death syndrome...
- Possible pathomechanisms of sudden infant death syndrome: key role of chronic hypoxia, infection/inflammation states, cytokine irregularities, and metabolic trauma in genetically predisposed infantsJoseph Prandota
Faculty of Medicine and Dentistry, and Department of Social Pediatrics, Faculty of Public Health, University Medical School, Wroclaw, Poland
Am J Ther 11:517-46. 2004..inflammation states, biochemical disorders, and genetic abnormalities are the most likely trigger of sudden infant death syndrome (SIDS)...
- Maternal smoking and alcohol consumption during pregnancy as risk factors for sudden infant deathM McDonnell-Naughton
Department of Nursing and Health Science, Athlone Institute of Technology, Co Westmeath
Ir Med J 105:105-8. 2012..The adjusted odds ratio for those consuming alcohol in all three trimesters was 3.59 (CI:1.40-9.20). Both of these risk factors are modifiable and need to be incorporated into antenatal education from a SIDS point of view...
- Breastfeeding and reduced risk of sudden infant death syndrome: a meta-analysisFern R Hauck
Department of Family Medicine, University of Virginia School of Medicine, PO Box 800729, Charlottesville, VA 22908, USA
Pediatrics 128:103-10. 2011Benefits of breastfeeding include lower risk of postneonatal mortality. However, it is unclear whether breastfeeding specifically lowers sudden infant death syndrome (SIDS) risk, because study results have been conflicting.
- A mechanism for sudden infant death syndrome (SIDS): stress-induced leak via ryanodine receptorsDavid J Tester
Department of Medicine, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55901, USA
Heart Rhythm 4:733-9. 2007b>Sudden infant death syndrome (SIDS) is the leading cause of postneonatal mortality in the United States...
- Risk factor changes for sudden infant death syndrome after initiation of Back-to-Sleep campaignFelicia L Trachtenberg
New England Research Institutes, Watertown, Massachusetts, USA
Pediatrics 129:630-8. 2012To test the hypothesis that the profile of sudden infant death syndrome (SIDS) changed after the Back-to-Sleep (BTS) campaign initiation, document prevalence and patterns of multiple risks, and determine the age profile of risk factors.
- Electrospray tandem mass spectrometry for analysis of acylcarnitines in dried postmortem blood specimens collected at autopsy from infants with unexplained cause of deathD H Chace
Neo Gen Screening, PO Box 219, Bridgeville, PA 15017, USA
Clin Chem 47:1166-82. 2001..inherited metabolic disorders may remain undiagnosed after postmortem examination and may be classified as sudden infant death syndrome...
- Recent national trends in sudden, unexpected infant deaths: more evidence supporting a change in classification or reportingCarrie K Shapiro-Mendoza
Maternal and Infant Health Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341 3717, USA
Am J Epidemiol 163:762-9. 2006The recent US decline in sudden infant death syndrome (SIDS) rates may be explained by a shift in how these deaths are classified or reported...
- Differences in mortality between late-preterm and term singleton infants in the United States, 1995-2002Kay M Tomashek
Maternal and Infant Health Branch, Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
J Pediatr 151:450-6, 456.e1. 2007..To assess differences in mortality between late-preterm (34-36 weeks) and term (37-41 weeks) infants...
- Loss-of-function mutations in the KCNJ8-encoded Kir6.1 K(ATP) channel and sudden infant death syndromeDavid J Tester
Department of Medicine, Division of Cardiovascular Diseases, Windland Smith Rice Sudden Death Genomics Laboratory, Mayo Clinic, Rochester, MN 55905, USA
Circ Cardiovasc Genet 4:510-5. 2011Approximately 10% of sudden infant death syndrome (SIDS) may stem from cardiac channelopathies. The KCNJ8-encoded Kir6...
- Diurnal temperature range as a novel risk factor for sudden infant deathChen Chu
Cardiovascular Center, Children s Hospital of Fudan University, Shanghai 201102, China
Biomed Environ Sci 24:518-22. 2011To assess the relationship between diurnal temperature range (DTR) and sudden infant death (SID) between 2001 and 2004 in Shanghai, China.
- Lack of association of the serotonin transporter polymorphism with the sudden infant death syndrome in the San Diego DatasetDavid S Paterson
Department of Pathology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatr Res 68:409-13. 2010..respiratory and autonomic function is postulated to underlie the pathogenesis of the majority of sudden infant death syndrome (SIDS) cases...
- Bed-sharing in the first four months of life: a risk factor for sudden infant deathJan H Ruys
Leiden University Medical Center, Reviuslaan 38, 2343 JR Oegstgeest, The Netherlands
Acta Paediatr 96:1399-403. 2007To investigate the risk of sudden infant death in the Netherlands during bed-sharing in the first half year of life and the protective effect of breastfeeding on it.
- Connexin43 mutation causes heterogeneous gap junction loss and sudden infant deathDavid W Van Norstrand
Mayo Clinic, MN 55905, USA
Circulation 125:474-81. 2012An estimated 10% to 15% of sudden infant death syndrome (SIDS) cases may stem from channelopathy-mediated lethal arrhythmias...
- Serotonin transporter gene variation is a risk factor for sudden infant death syndrome in the Japanese populationN Narita
Department of Pediatrics, Dokkyo University, School of Medicine, Koshigaya Hospital, Saitama, Japan
Pediatrics 107:690-2. 2001..Therefore, we aimed to identify the possibility that specific allele variants of the 5-HTT gene can be found as a genetic background for sudden infant death syndrome (SIDS).
- An 8 year study of risk factors for SIDS: bed-sharing versus non-bed-sharingC McGarvey
National Sudden Infant Death Register, George s Hall, The Children s University Hospital, Temple St, Dublin 1, Ireland
Arch Dis Child 91:318-23. 2006It is unclear if it is safe for babies to bed share with adults. In Ireland 49% of sudden infant death syndrome (SIDS) cases occur when the infant is bed-sharing with an adult.
- Hazardous cosleeping environments and risk factors amenable to change: case-control study of SIDS in south west EnglandPeter S Blair
Department of Community Based Medicine, University of Bristol
BMJ 339:b3666. 2009To investigate the factors associated with sudden infant death syndrome (SIDS) from birth to age 2 years, whether recent advice has been followed, whether any new risk factors have emerged, and the specific circumstances in which SIDS ..
- Factors associated with the transition to nonprone sleep positions of infants in the United States: the National Infant Sleep Position StudyM Willinger
Pregnancy and Perinatology Branch, Center for Research for Mothers and Children, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892 7510, USA
JAMA 280:329-35. 1998Studies have demonstrated strong associations between the prone sleep position (on the stomach) and sudden infant death syndrome (SIDS)...
- The G protein beta3 subunit 825C allele is associated with sudden infant death due to infectionSiri Hauge Opdal
Institute of Forensic Medicine, University of Oslo, Department of Medical Biochemistry, Rikshospitalet University Hospital, Oslo, Norway
Acta Paediatr 95:1129-32. 2006..The reported association between the Gbeta3s protein and increased immune cell function in humans makes this polymorphism highly interesting both with regard to sudden infant death syndrome (SIDS) and deleterious infectious disease.
- A perspective on SIDS pathogenesis. the hypotheses: plausibility and evidencePaul N Goldwater
Microbiology and Infectious Diseases, SA Pathology at the Women s and Children s Hospital
BMC Med 9:64. 2011Several theories of the underlying mechanisms of Sudden Infant Death Syndrome (SIDS) have been proposed...
- Intrathoracic petechial hemorrhages in sudden infant death syndrome and other infant deaths: time for re-examinationPaul N Goldwater
Microbiology and Infectious Diseases Department, The Women s and Children s Hospital, Discipline of Paediatrics, Children, Youth and Women s Health Service, North Adelaide, South Australia 5006, Australia
Pediatr Dev Pathol 11:450-5. 2008..pathogenesis of intrathoracic petechial hemorrhages through a retrospective autopsy report review of 174 sudden infant death syndrome (SIDS) cases (2004 definition) and 67 age-matched comparison deaths...
- The frequency of molecular detection of virulence genes encoding cytolysin A, high-pathogenicity island and cytolethal distending toxin of Escherichia coli in cases of sudden infant death syndrome does not differ from that in other infant deaths and healtAmanda R Highet
Department of Microbiology and Infectious Diseases, Women s and Children s Hospital, North Adelaide, South Australia, Australia
J Med Microbiol 58:285-9. 2009Consistent pathological findings in sudden infant death syndrome (SIDS) are seen which display similarities to the pathogenesis of toxaemic shock and/or sepsis...
- Review of risk factors for sudden infant death syndromeF M Sullivan
Division of Pharmacology and Toxicology, United Medical School, University of London, UK
Paediatr Perinat Epidemiol 15:144-200. 2001b>Sudden infant death syndrome (SIDS) accounts for the largest number of deaths during the first year of life in developed countries...
- Clinical correlates, natural history and outcome of neonatal apnoeaTerry M Baird
Case Western Reserve University, 11100 Euclid Ave, Cleveland, OH 44106, USA
Semin Neonatol 9:205-11. 2004..Infants who have apnoea in the newborn period are thought not to be at higher risk for sudden infant death syndrome (SIDS)...
- SIDS: past, present and futureEdwin A Mitchell
Department of Paediatrics, University of Auckland, Auckland, New Zealand
Acta Paediatr 98:1712-9. 2009..Conclusion: SIDS is preventable. Application of what we currently know could eliminate SIDS. The challenge is to find ways of implementing our knowledge...
- Sudden infant death syndrome: how significant are the cardiac channelopathies?David J Tester
Department of Medicine, Mayo Clinic College of Medicine, United States
Cardiovasc Res 67:388-96. 2005..This tragedy is compounded when the infant's death is unexpected and unexplained, signed out as sudden infant death syndrome (SIDS)...
- Prenatal nicotine-exposure alters fetal autonomic activity and medullary neurotransmitter receptors: implications for sudden infant death syndromeJhodie R Duncan
Dept of Pathology, Enders 1112 1, Children s Hospital Boston, 300 Longwood Ave, Boston, MA 02115, USA
J Appl Physiol (1985) 107:1579-90. 2009During pregnancy, exposure to nicotine and other compounds in cigarette smoke increases the risk of the sudden infant death syndrome (SIDS) two- to fivefold...
- Social deprivation and the causes of stillbirth and infant mortalityZ E Guildea
Department of Child Health, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, UK
Arch Dis Child 84:307-10. 2001..The early neonatal mortality rate was not significantly associated with deprivation. Sudden infant death syndrome showed a 307% (95% CI 197% to 456%) increase in mortality across the range of deprivation...
- An infectious aetiology of sudden infant death syndromeA R Highet
Department of Microbiology and Infectious Diseases, Children, Youth and Women s Health Service, Women s and Children s Hospital, North Adelaide, SA, Australia
J Appl Microbiol 105:625-35. 2008Due attention has been given to infectious agents and immune responses to infection in sudden infant death syndrome (SIDS)...
- Smoking and the sudden infant death syndromeE A Mitchell
Department of Paediatrics, University of Auckland, New Zealand
Rev Environ Health 21:81-103. 2006..are (a) to critically examine the epidemiologic evidence for a possible association between smoking and the sudden infant death syndrome (SIDS), (b) to review the pathology and postulated physiological mechanism(s) by which smoking ..
- International trends in sudden infant death syndrome: stabilization of rates requires further actionFern R Hauck
University of Virginia School of Medicine, Department of Family Medicine, PO Box 800729, Charlottesville, VA 22908 0729, USA
Pediatrics 122:660-6. 2008
- Cardiorespiratory events recorded on home monitors: Comparison of healthy infants with those at increased risk for SIDSR Ramanathan
Department of Pediatrics, Yale Medical School, Box 208064, New Haven, CT 06520-8064, USA
JAMA 285:2199-207. 2001..monitors designed to identify cardiorespiratory events are frequently used in infants at increased risk for sudden infant death syndrome (SIDS), but the efficacy of such devices for this use is unproven...
- The triple risk hypotheses in sudden infant death syndromeWarren G Guntheroth
Department of Pediatrics, University of Washington School of Medicine, Seattle, Washington 98195 6320, USA
Pediatrics 110:e64. 2002b>Sudden infant death syndrome (SIDS) victims were regarded as normal as a matter of definition (Beckwith 1970) until 1952 when Kinney and colleagues argued for elimination of the clause, "unexpected by history...
- Studying sudden and unexpected infant deaths in a time of changing death certification and investigation practices: evaluating sleep-related risk factors for infant death in New York CityLindsay Senter
Bureau of Maternal, Infant and Reproductive Health, New York City Department of Health and Mental Hygiene, 2 Lafayette Street, New York, NY 10007, USA
Matern Child Health J 15:242-8. 2011..This will help jurisdictions interpret their infant mortality statistics, which in turn will improve education and prevention efforts...
- Influence of environmental factors in higher risk of sudden infant death syndrome linked with parental mental illnessRoger T Webb
Centre for Women s Mental Health and Health Methodology Research Group, University of Manchester, Room 2 311, University Place, Oxford Road, Manchester M13 9PL, England
Arch Gen Psychiatry 67:69-77. 2010Since national risk reduction campaigns have been conducted, sudden infant death syndrome (SIDS) has become increasingly concentrated among disadvantaged families, including those affected by mental illness...
- Infant-parent co-sleeping in an evolutionary perspective: implications for understanding infant sleep development and the sudden infant death syndromeJ J McKenna
Pomona College, Claremont, California 91711
Sleep 16:263-82. 1993..of optimal sleep patterning in infants and confer other benefits, including reducing the risk of the sudden infant death syndrome (SIDS). These postulations by McKenna are considered from different perspectives by the coauthors...
- Sarcomeric gene mutations in sudden infant death syndrome (SIDS)Maria Brion
Genetics of Cardiovascular and Ophthalmologic Diseases, Hospital University Complex of Santiago CHUS, Santiago de Compostela, Spain
Forensic Sci Int 219:278-81. 2012In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age...
- An audit of the use of definitions of sudden infant death syndrome (SIDS)Roger W Byard
Discipline of Pathology, Level 3, Medical School North, The University of Adelaide, Frome Road, Adelaide 5005, Australia
J Forensic Leg Med 14:453-5. 2007..Failure to use standard published definitions of SIDS and/or to clearly specify the definition that has been followed may severely hamper the evaluation of SIDS research...
- The metabolic investigation of sudden infant deathSimon E Olpin
Department of Clinical Chemistry, Sheffield Children s Hospital, Sheffield S10 2TH, UK
Ann Clin Biochem 41:282-93. 2004..In particular, inherited disorders of fatty acid oxidation may closely mimic sudden infant death syndrome. Post-mortem investigations offer the final opportunity to establish a diagnosis...
- A serotonin malfunction hypothesis by finding clear mutual relationships between several risk factors and symptoms associated with sudden infant death syndromeN Okado
Neurobiology Laboratory, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki 305 8577, Japan
Med Hypotheses 58:232-6. 2002..variants in the promoter of serotonin transporter (5-HTT) gene have been shown as a novel risk factor for sudden infant death syndrome (SIDS)...
- Sudden infant death syndrome in twins and singletonsPeter O D Pharoah
Department of Public Health, University of Liverpool, Liverpool, United Kingdom
Twin Res Hum Genet 10:644-8. 2007..The aim of this study is to investigate whether zygosity is a risk factor for the sudden infant death syndrome (SIDS)...
- Risk factors, diagnosis and prevention of sudden unexpected infant deathAkihiro Takatsu
Department of Forensic Medicine, Jikei University School of Medicine, 3 25 8, Nishi Shinbashi, Minato ku, Tokyo 105 8461, Japan
Leg Med (Tokyo) 9:76-82. 2007..During the sudden infant death syndrome (SIDS) epidemic, many reports described the risk factors of SIDS as well as mechanical suffocation ..
- Sudden fetal and infant deaths: shared characteristics and distinctive featuresWilliam P Fifer
Department Psychiatry, Columbia University, and Psychiatric Institute New York, 10032, USA
Semin Perinatol 26:89-96. 2002Recent evidence suggests sudden infant death syndrome (SIDS) infants have a diminished capacity to respond to autonomic challenges during a vulnerable developmental period...
- Repeat sudden unexpected and unexplained infant deaths: natural or unnatural?R G Carpenter
Medical Statistics Unit, Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
Lancet 365:29-35. 2005..We aimed to estimate the probability that a second infant death is natural versus unnatural...
- Heterozygous nonsense SCN5A mutation W822X explains a simultaneous sudden infant death syndromeEmanuela Turillazzi
Department of Forensic Pathology, University of Foggia, Ospedale Colonnello D Avanzo, Viale degli Aviatori 1, 71100, Foggia, Italy
Virchows Arch 453:209-16. 2008The sudden, unexpected, and unexplained death of both members of a set of healthy twins (simultaneous sudden infant death syndrome (SSIDS)) is defined as a case in which both infants meet the definition of sudden infant death syndrome ..
- Prenatal to early postnatal nicotine exposure impairs central chemoreception and modifies breathing pattern in mouse neonates: a probable link to sudden infant death syndromeJaime Eugenin
Laboratory of Neural Systems, Department of Biology, Faculty of Chemistry and Biology, Universidad de Santiago de Chile, Santiago 9160000, Chile
J Neurosci 28:13907-17. 2008Nicotine is a neuroteratogen and is the likely link between maternal cigarette smoking during pregnancy and sudden infant death syndrome (SIDS)...
- Sudden infant death syndrome (SIDS) and child care centres (CCC)U Kiechl-Kohlendorfer
Department of Paediatrics, Division of Neonatology, Neuropaediatrics and Metabolic Diseases, Innsbruck Medical University, Innsbruck, Austria
Acta Paediatr 97:844-5. 2008Our aim was to review the risk of sudden infant death syndrome (SIDS) when infants are in child care (CC), to discuss factors potentially responsible for SIDS in this setting and to describe the impact of previous information campaigns ..
- Unexplained infant and child death: a review of sudden infant death syndrome, sudden unexplained infant death, and child maltreatment fatalities including shaken baby syndromeAlice W Newton
Department of Pediatrics, Harvard Medical School, and the Child Protection Program of Massachusetts General Hospital, Boston, Massachusetts 02115, USA
Curr Opin Pediatr 18:196-200. 2006This review will examine the most recent published literature on Sudden Infant Death, Sudden Unexplained Infant Death, infant and child death due to maltreatment, and Shaken Baby Syndrome.
- Molecular typing of Pneumocystis jirovecii found in formalin-fixed paraffin-embedded lung tissue sections from sudden infant death victimsM Chabé
Ecology of Parasitism, EA 3609 IFR17, Pasteur Institute of Lille, 1 rue du Professeur Calmette BP245, 59019 Lille, France
Microbiology 150:1167-72. 2004..studies have provided histological evidence of an association between primary Pneumocystis infection and sudden infant death syndrome (SIDS)...
- Sudden infant death syndrome and sleeping position in pre-term and low birth weight infants: an opportunity for targeted interventionP S Blair
Institute of Child Life and Health, Department of Clinical Science, South Bristol, University of Bristol, UK
Arch Dis Child 91:101-6. 2006To determine the combined effects of sudden infant death syndrome (SIDS) risk factors in the sleeping environment for infants who were "small at birth" (pre-term (<37 weeks), low birth weight (<2500 g), or both).
- NHE3 in the human brainstem: implication for the pathogenesis of the sudden infant death syndrome (SIDS)?Martin Wiemann
University of Duisburg Essen, Department of Physiology
Adv Exp Med Biol 605:508-13. 2008..As an insufficient drive to breath may be a final event causing sudden infant death, we compared the expression of NHE3 mRNA in a collective of children who died from non-natural causes to an ..
- Sudden unexpected infant death and bedsharing: referrals to the Wellington Coroner 1997-2006Alistair Escott
School of Medicine andHealth Sciences, University of Otago, Wellington, PO Box 7343, Wellington, New Zealand
N Z Med J 122:59-68. 2009..To describe the factors associated with sudden unexpected infant deaths, for which there was no clear medical diagnosis, referred to the Wellington-based coronial paediatric pathology service over the decade from 1997 to 2006...
- The contribution of prone sleeping position to the racial disparity in sudden infant death syndrome: the Chicago Infant Mortality StudyFern R Hauck
Department of Family Medicine, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA
Pediatrics 110:772-80. 2002Rates of sudden infant death syndrome (SIDS) are over twice as high among African Americans compared with Caucasians...
- Sudden unexpected death in infancy in DenmarkBo Gregers Winkel
The Danish National Research Foundation Centre for Cardiac Arrhythmia DARC, Copenhagen, Denmark
Scand Cardiovasc J 45:14-20. 2011Incidence of sudden unexpected death in infancy (SUDI) and sudden infant death syndrome (SIDS) differs among studies and non-autopsied cases are difficult to assess.
- Lung tissue concentrations of nicotine in sudden infant death syndrome (SIDS)Kristen I McMartin
Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
J Pediatr 140:205-9. 2002To compare lung concentrations of nicotine and cotinine in cases of sudden infant death syndrome (SIDS) and controls.
- Sudden Infant Death Syndrome and the time of death: factors associated with night-time and day-time deathsP S Blair
Institute of Child Life and Health, Department of Clinical Science, South Bristol, University of Bristol, UK
Int J Epidemiol 35:1563-9. 2006To investigate the diurnal occurrence of Sudden Infant Death Syndrome (SIDS) and interaction with established risk factors in the infant sleeping environment.
- Genetics of the sudden infant death syndromeCornelius Courts
Institute of Forensic Medicine, University of Bonn, Bonn, Germany
Forensic Sci Int 203:25-33. 2010The sudden infant death syndrome (SIDS) is currently defined as "the sudden unexpected death of an infant less than 1 year of age with onset of the fatal episode apparently occurring during sleep, that remains unexplained after a ..
- Mother-infant cosleeping, breastfeeding and sudden infant death syndrome: what biological anthropology has discovered about normal infant sleep and pediatric sleep medicineJames J McKenna
Department of Anthropology and Mother Baby Behavioral Sleep Laboratory, University of Notre Dame, Notre Dame, IN 46556, USA
Am J Phys Anthropol . 2007....
- The value of a thorough protocol in the investigation of sudden infant deathsD W Sadler
University Department of Forensic Medicine, Dundee Royal Infirmary, UK
J Clin Pathol 51:689-94. 1998..To review the diagnostic value of using a thorough necropsy protocol for the investigation of sudden infant deaths, with particular emphasis on the value of routine ancillary laboratory investigations...
- Cardiovascular control during sleep in infants: Implications for Sudden Infant Death SyndromeRosemary S C Horne
Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Melbourne, Australia
Sleep Med 11:615-21. 2010..failure of cardiovascular control mechanisms in particular is believed to play a role in the final event of Sudden Infant Death Syndrome (SIDS)...
- Cardiac ion channel mutations in the sudden infant death syndromeEva C Klaver
Heart Failure Research Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Int J Cardiol 152:162-70. 2011b>Sudden infant death syndrome (SIDS) is characterized by the sudden death of an infant that occurs during sleep and remains unexplained despite thorough examination...
- Evidence for an association between infant mortality and a carnitine palmitoyltransferase 1A genetic variantBradford D Gessner
Alaska Division of Public Health, PO Box 240249, Suite 354, Anchorage, AK 99524, USA
Pediatrics 126:945-51. 2010..1436C→T) in the gene coding for carnitine palmitoyltransferase type 1A (CPT1A). We sought to determine whether these 2 findings were related...
- [Epidemiology of 25 years of crib death (sudden infant death syndrome) in the Netherlands; incidence of crib death and prevalence of risk factors in 1980-2004]G A de Jonge
Centraal Bureau voor de Statistiek, Voorburg
Ned Tijdschr Geneeskd 149:1273-8. 2005To describe the prevalence of risk factors and the incidence of cot death (sudden infant death syndrome; SIDS) in the Netherlands during the last 25 years.
- Sudden Infant Death Syndrome and prenatal maternal smoking: rising attributed risk in the Back to Sleep eraMark E Anderson
Department of Community Health Services, Division of Pediatrics, Denver Health and Hospitals Authority, Denver, Colorado, USA
BMC Med 3:4. 2005Parental smoking and prone sleep positioning are recognized causal features of Sudden Infant Death. This study quantifies the relationship between prenatal smoking and infant death over the time period of the Back to Sleep campaign in ..
- Sudden infant death syndrome and maternal depressionLouise M Howard
Health Services and Population Research Department, Institute of Psychiatry, United Kingdom
J Clin Psychiatry 68:1279-83. 2007To investigate whether there is an association between sudden infant death syndrome (SIDS) and perinatal depression.
- Exposure to cigarette smoke, a major risk factor for sudden infant death syndrome: effects of cigarette smoke on inflammatory responses to viral infection and bacterial toxinsM W Raza
Department of Medical Microbiology, University of Edinburgh, Medical School, UK
FEMS Immunol Med Microbiol 25:145-54. 1999Exposure to cigarette smoke is a major risk factor for sudden infant death syndrome and also for respiratory infections in children...
- Stable prevalence but changing risk factors for sudden infant death syndrome in child care settings in 2001Rachel Y Moon
Division of General Pediatrics and Community Health, Goldberg Center for Community Pediatric Health, Washington, DC, USA
Pediatrics 116:972-7. 2005A total of 20% of sudden infant death syndrome (SIDS) cases in the 1990s occurred in child care settings. This is much higher than the 8% expected from Census Bureau data...
- Sudden infant death syndrome: overview and updateRoger W Byard
Division of Pathology, Forensic Science Centre, 21 Divett Place, Adelaide 5000, South Australia, Australia
Pediatr Dev Pathol 6:112-27. 2003The past decade and a half has seen marked changes in the epidemiology of sudden infant death syndrome (SIDS)...
- Recommendations for sudden infant death syndrome prevention: a discussion documentE A Mitchell
Department of Paediatrics, University of Auckland, Private Bag 92019, Auckland, New Zealand
Arch Dis Child 92:155-9. 2007This article reviews the evidence for the current UK Department of Health recommendations for prevention of sudden infant death syndrome (SIDS) and suggests other factors that should be considered...
- Unexplained sudden death, including sudden infant death syndrome (SIDS), in the first and second years of life: case definition and guidelines for collection, analysis, and presentation of immunization safety dataGerhard Jorch
University of Magdeburg, Magdeburg, Germany
Vaccine 25:5707-16. 2007
- Sterile site infection at autopsy in sudden unexpected deaths in infancyP N Goldwater
The Women s and Children s Hospital, and The University of Adelaide Discipline of Paediatrics, Children, Youth and Women s Health Service, 72 King William Road, North Adelaide, South Australia 5006, Australia
Arch Dis Child 94:303-7. 2009..To examine and compare bacteriological findings at autopsy of cases of sudden unexpected infant death and those of deaths from other cause...
- Sudden infant death syndrome: a critical review of approaches to researchP N Goldwater
Microbiology and Infectious Diseases Department, The Women s and Children s Hospital, North Adelaide, South Australia 5006
Arch Dis Child 88:1095-100. 2003..Close examination of the pathological clues would provide better insights into the mechanisms underlying this enigmatic and heartbreaking problem...
- Small for gestational age infants and sudden infant death syndrome: a confluence of complex conditionsCarl E Hunt
Chevy Chase, Maryland 20815, USA
Arch Dis Child Fetal Neonatal Ed 92:F428-9. 2007
- Changing conclusions on secondhand smoke in a sudden infant death syndrome review funded by the tobacco industryElisa K Tong
Division of General Internal Medicine Fellowship Program, Cardiovascular Research Institute, University of California, San Francisco, California 94143 1390, USA
Pediatrics 115:e356-66. 2005..Secondhand smoke (SHS) has been linked causally with sudden infant death syndrome (SIDS) in major health reports...
- Staphylococcal enterotoxin genes are common in Staphylococcus aureus intestinal flora in Sudden Infant Death Syndrome (SIDS) and live comparison infantsAmanda R Highet
Department of Microbiology and Infectious Diseases, SA Pathology at the Women s and Children s Hospital, North Adelaide, SA, Australia
FEMS Immunol Med Microbiol 57:151-5. 2009Pathological and epidemiological findings in sudden infant death syndrome (SIDS) suggest an infectious aetiology with indications of involvement of staphylococcal enterotoxins (SEs)...
- Incongruent cerebral growth in sudden infant death syndromeHazim Kadhim
Anatomic Pathology Service, Brugmann University Hospital, Brussels, Belgium
J Child Neurol 20:244-6. 2005b>Sudden infant death syndrome remains a leading cause of post-neonatal mortality in developed countries. Its etiopathogenic mechanisms are unknown...
- Myocardial inflammation, cellular death, and viral detection in sudden infant death caused by SIDS, suffocation, or myocarditisHenry F Krous
Department of Pathology, University of California San Diego, La Jolla, CA 92037, USA
Pediatr Res 66:17-21. 2009..Very mild myocardial lymphocyte and macrophage infiltration and scattered necrotic cardiomyocytes in SIDS are not pathologic, but may occur after the developing heart is exposed to environmental pathogens, including viruses...
- Immunohistochemical and molecular-pathological diagnosis of myocarditis in cases of suspected sudden infant death syndrome (SIDS)--a multicenter studyReinhard Dettmeyer
Institute of Forensic Medicine, University of Giessen, Frankfurter Street 58, D 35392 Giessen, Germany
Leg Med (Tokyo) 11:S124-7. 2009..Preliminary criteria for cellular immunohistochemical diagnosis of viral myocardial affections derived from these findings were suggested...
- Intrathoracic petechiae in SIDS: a retrospective population-based 15-year studyHenry F Krous
Rady Children s Hospital San Diego, 3020 Children s Way, M5007, San Diego, CA 92123, USA
Forensic Sci Med Pathol 4:234-9. 2008Intrathoracic petechiae (IP), the most common gross finding in sudden infant death syndrome (SIDS) cases at autopsy, suggest upper airway obstruction (UAO) occurs during the terminal event...
- Novel hypothesis for unexplained sudden unexpected death in infancy (SUDI)A R Highet
Department of Microbiology and Infectious Diseases, SA Pathology, Women s and Children s Hospital, North Adelaide, South Australia, Australia
Arch Dis Child 94:841-3. 2009..The objective was to assess these observations in the context of the pathology and epidemiology of sudden infant death syndrome (SIDS) in relation to the role of infection and inflammation as triggers of these deaths.
- Sudden infant death syndrome (SIDS) shortly after hexavalent vaccination: another pathology in suspected SIDS?Giulia Ottaviani
Institute of Pathology, University of Milan, Via della Commenda 19, Milan 20122, Italy
Virchows Arch 448:100-4. 2006..Participants included pathologists with experience in the field of vaccines and sudden infant death syndrome who conducted autopsies...
- The role of respiratory control disorders in SIDSBradley T Thach
Department of Pediatrics, Washington University School of Medicine, 660 S Euclid, Campus Box 8208, St Louis, MO 63110, USA
Respir Physiol Neurobiol 149:343-53. 2005..In drawing conclusions it is well to recognize that mechanisms leading to death in SIDS are heterogeneous and therefore there is room for several plausible theories for respiratory or circulatory abnormalities contributing to SIDS...
- Sudden infant death syndrome: no increased risk after immunisationM M T Vennemann
Institute of Legal Medicine, University of Munster, and Children s Hospital, University of Magdeburg, Germany
Vaccine 25:336-40. 2007....
- Prevalence of congenital adrenal hyperplasia among sudden infant death in the Czech Republic and AustriaKristina A Strnadová
Department of Pediatrics, 3rd Faculty of Medicine, Charles University, CZ 100 81, Prague, Czech Republic
Eur J Pediatr 166:1-4. 2007..Hence, newborn screening would have prevented these deaths had it been available. In addition, we have shown that the I2 point mutation that is expected to lead to simple virilizing form may lead to a fatal outcome...
- Why babies should never sleep alone: a review of the co-sleeping controversy in relation to SIDS, bedsharing and breast feedingJames J McKenna
University of Notre Dame, Notre Dame, Indiana, IN 46556, USA
Paediatr Respir Rev 6:134-52. 2005....
- Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant deathG Ottaviani
Institute of Pathology, Lino Rossi Research Centre for the study and prevention of unexpected perinatal death and SIDS, University of Milan, Italy
J Clin Pathol 59:497-500. 2006..Her sudden death offered a unique insight into the possible role of delayed neuronal maturation and hypoplasia of the hypoglossal nucleus in representing a likely morphological substrate of sudden death...
- Organ weights in cases of sudden infant death syndrome: a German studyTony Fracasso
Institute of Legal Medicine, University of Munster, Germany
Am J Forensic Med Pathol 30:231-4. 2009Despite its decreasing incidence, sudden infant death syndrome (SIDS) still remains an important cause of death in infancy. Since Felix Platter described the case of a child suffocated because of a massive goiter (Platter E...
- Serotypes of Escherichia coli in sudden infant death syndromeJ L Pearce
Department of Agricultural Sciences, La Trobe University, Melbourne, Vic, Australia
J Appl Microbiol 108:731-5. 2010To examine the diversity of Escherichia coli serotypes found in the intestinal contents of infants who died of Sudden Infant Death Syndrome (SIDS) compared with that in comparison infants.
- Rebreathing of exhaled gases: importance as a mechanism for the causal association between prone sleep and sudden infant death syndromeJ S Kemp
Division of Pulmonary Medicine, St. Louis Children's Hospital, St. Louis, Missouri 63110, USA
Sleep 19:S263-6. 1996Twenty to 52% of sudden infant death syndrome (SIDS) victims are found dead with their noses and mouths turned into underlying bedding...
- What is the mechanism of sudden infant deaths associated with co-sleeping?Christine G McIntosh
Dept of Physiology, University of Auckland, Private Bag 92019, Auckland 1023, New Zealand
N Z Med J 122:69-75. 2009The risk of Sudden Infant Death Syndrome (SIDS) has fallen dramatically in the "Back to Sleep" era; however, half the cases now occur when the infant has been sleeping in bed with another person...
- Elevated serum concentrations of beta-tryptase, but not alpha-tryptase, in Sudden Infant Death Syndrome (SIDS). An investigation of anaphylactic mechanismsM G Buckley
Immunopharmacology Group, Southampton General Hospital, Southampton, UK
Clin Exp Allergy 31:1696-704. 2001BACKGROUND: Sudden Infant Death Syndrome, (SIDS) or cot death, remains the most common category of post-perinatal death in the UK...
- Interleukin-2 as a neuromodulator possibly implicated in the physiopathology of sudden infant death syndromeHazim Kadhim
Neuropathology Unit, Department of Anatomic Pathology, Centre Hospitalier Universitaire Brugmann, Universite Libre De Bruxelles U L B, Place Van Gehuchten 4, 1020 Brussels, Belgium
Neurosci Lett 480:122-6. 2010..centers, including those controlling cardiorespiratory- and sleep/arousal pathophysiology, is reported in sudden infant death syndrome (SIDS). Biological mechanisms underlying SIDS, however, remain unclear...
- Sudden infant death syndrome--a defect in circulatory control?T Matthews
University College Dublin, Department of Paediatrics, Temple Street Children s Hospital and The Rotunda Hospital, Dublin, Ireland
Child Care Health Dev 28:41-3. 2002The majority of Sudden Infant Death Syndrome (SIDS) infants die during sleep and especially during the overnight sleep period...
- Heart weight in infants--a comparison between sudden infant death syndrome and other causes of deathP Råsten-Almqvist
Department of Forensic Medicine, Karolinska Institute, Stockholm, Sweden
Acta Paediatr 89:1062-7. 2000..1998, out of 468 infants autopsied at the Department of Forensic Medicine in Stockholm, Sweden, 331 died of sudden infant death syndrome (SIDS), while 137 died of other causes...
- Concurrent risks in sudden infant death syndromeBarbara M Ostfeld
University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Department of Pediatrics, PO Box 19, New Brunswick, NJ 08903, USA
Pediatrics 125:447-53. 2010Despite improved education on safe sleep, infants are still exposed to multiple risks for sudden infant death syndrome (SIDS)...
- Critical diaphragm failure in sudden infant death syndromePontus Max Axel Siren
JGK Memorial Research Library, Snellmanin k 15, 00170, Helsinki, Finland
Ups J Med Sci 116:115-23. 2011b>Sudden infant death syndrome (SIDS) is the leading cause of death in infants between the ages of 1 and 12 months in developed countries. SIDS is by definition a diagnosis of exclusion, and its mechanism of action is unknown...
- Sudden infant death syndrome, bedsharing, parental weight, and age at deathC Carroll-Pankhurst
Mandel School of Applied Social Sciences, Case Western Reserve University, Cleveland, Ohio 44106 4945, USA
Pediatrics 107:530-6. 2001To assess the role of parental bedsharing in sudden infant death syndrome (SIDS)-like deaths, this study examines the hypothesis that, compared with other SIDS cases, the age distribution of deaths associated with bedsharing should be ..
- Birth weight- and gestational age-specific sudden infant death syndrome mortality: United States, 1991 versus 1995M H Malloy
Department of Pediatrics, University of Texas Medical Branch, Galveston, Texas 77555 0526, USA
Pediatrics 105:1227-31. 2000To estimate the changes in birth weight- and gestational age-specific sudden infant death syndrome (SIDS) mortality rates since the publication of the sleep-positioning recommendations by the American Academy of Pediatrics Task Force on ..
- Effects of the supine and prone position on diaphragm thickness in healthy term infantsV K Rehan
Department of Pediatrics, Memorial Hospital of Rhode Island, Pawtucket, Rhode Island, USA
Arch Dis Child 83:234-8. 2000The physiological basis underlying the decline in the incidence of sudden infant death syndrome (SIDS) associated with changing the sleep position from prone to supine remains unknown.
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2009..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Neonatal Long QT Syndrome and Sudden Infant DeathALFRED GEORGE; Fiscal Year: 2007..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Neonatal Long QT Syndrome and Sudden Infant DeathAlfred L George; Fiscal Year: 2010..In neonates and infants, sudden unexplained death is classified as the sudden infant death syndrome (SIDS) when rigorous efforts to identify the cause of death including a forensic examination are ..
- Coordination of orofacial and respiratory movementsDetlef H Heck; Fiscal Year: 2010..in coordinating orofacial and respiratory movements are implicated in human health conditions such as sudden infant death syndrome (SIDS), swallowing dysfunction (dysphagia) and speech disorders (dysarthria)...
- Nicotine Modulation of Parasympathetic Cardiac NeuronsDavid Mendelowitz; Fiscal Year: 2009..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS). SIDS is the leading cause of death among infants who are 1 month to 1 year old...
- MECHANISM OF CARDIORESPIRATORY RHYTHM IN NEONATESDavid Mendelowitz; Fiscal Year: 2011..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS)...
- MECHANISM OF CARDIORESPIRATORY RHYTHM IN NEONATESDavid Mendelowitz; Fiscal Year: 2010..However an exaggerated diving reflex has been implicated in sudden infant death syndrome (SIDS)...
- Developmental Genetics of Serotonin Neuron Subtypes in Brain Reward CircuitsSusan Dymecki; Fiscal Year: 2007..pathological anxiety, to childhood developmental disorders such as autism, fetal alcohol syndrome, and the sudden infant death syndrome. Each disorder differs in clinical feature, suggesting heterogeneity in serotonin neuron function...
- The upper airway and the Sudden Infant Death SyndromeDonald Bartlett; Fiscal Year: 2010The incidence of the Sudden Infant Death Syndrome (SIDS) has decreased substantially in the United States and elsewhere as a result of educational campaigns favoring the supine posture for sleeping infants...
- Improving the Self-Efficacy of African American Parents in Infant Supine SleepKathryn L Moseley; Fiscal Year: 2010..African American infants also die of Sudden Infant Death Syndrome (SIDS) at rates 2-3 times greater than non-Hispanic White infants...
- Developmental defects in serotonin neurons and the response to O2 and CO2George Richerson; Fiscal Year: 2007b>Sudden infant death syndrome (SIDS) is the most common cause of post neonatal infant death in the U.S. The mechanisms are unknown, but abnormalities in the serotonin system have been consistently found in autopsy studies...
- Developmental defects in serotonin neurons and the response to O2 and CO2George Richerson; Fiscal Year: 2009b>Sudden infant death syndrome (SIDS) is the most common cause of post neonatal infant death in the U.S. The mechanisms are unknown, but abnormalities in the serotonin system have been consistently found in autopsy studies...
- Mu Opioid Receptor Regulation in Neonatal BrainstemGEORGE OLSEN; Fiscal Year: 2006..These neonates exhibit withdrawal hyperventilation and an increased incidence of sudden infant death syndrome (SIDS)...