ascites

Summary

Summary: Accumulation or retention of free fluid within the peritoneal cavity.

Top Publications

  1. ncbi Ovarian cancer metastasis: integrating insights from disparate model organisms
    Honami Naora
    Department of Molecular Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Nat Rev Cancer 5:355-66. 2005
  2. ncbi Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation
    Dorina Belotti
    Laboratory of Biology, Department of Oncology, Mario Negri Institute for Pharmacological Research, 24125 Bergamo, Italy
    Cancer Res 63:5224-9. 2003
  3. ncbi Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer
    Yoko Hasumi
    Division of Genetic Therapeutics, Jichi Medical School, Tochigi 329 0498, Japan
    Cancer Res 62:2019-23. 2002
  4. ncbi Guidelines on the management of ascites in cirrhosis
    K P Moore
    The UCL Institute of Hepatology, Royal Free and University College Medical School, UCL, Rowland Hill St, London NW3 2PF, UK
    Gut 55:vi1-12. 2006
  5. ncbi Proinflammatory and immunosuppressive serum, ascites and cyst fluid cytokines in patients with early and advanced ovarian cancer and benign ovarian tumors
    Marek Nowak
    Department of Gynecologic Surgery, Polish Mother s Memorial Hospital Research Institute, Poland
    Neuro Endocrinol Lett 31:375-83. 2010
  6. ncbi CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
    Ilona Kryczek
    Tulane University Health Science Center, New Orleans, LA 70112, USA
    Cancer Res 65:465-72. 2005
  7. ncbi Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer
    G Scambia
    Department of Gynecology and Obstetrics, Catholic University, Rome, Italy
    Br J Cancer 71:354-6. 1995
  8. ncbi Complete remission of ovarian cancer induced intractable malignant ascites with intraperitoneal bevacizumab. Immunological observations and a literature review
    Filippo Bellati
    Institute of Gynecology and Obstetrics, Sapienza University, Rome, Italy
    Invest New Drugs 28:887-94. 2010
  9. ncbi The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
    Markus M Heiss
    Department of Surgery, Cologne Merheim Medical Center, University of Witten Herdecke, Cologne, Germany
    Int J Cancer 127:2209-21. 2010
  10. ncbi Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
    Steffen Runz
    Tumor Immunology Programme D010, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Gynecol Oncol 107:563-71. 2007

Detail Information

Publications271 found, 100 shown here

  1. ncbi Ovarian cancer metastasis: integrating insights from disparate model organisms
    Honami Naora
    Department of Molecular Therapeutics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA
    Nat Rev Cancer 5:355-66. 2005
    ..Genetic analysis of border-cell migration in the Drosophila melanogaster ovary provides clues that will improve our understanding of ovarian cancer metastasis at the molecular level, and also might lead to potential therapeutic targets...
  2. ncbi Matrix metalloproteinases (MMP9 and MMP2) induce the release of vascular endothelial growth factor (VEGF) by ovarian carcinoma cells: implications for ascites formation
    Dorina Belotti
    Laboratory of Biology, Department of Oncology, Mario Negri Institute for Pharmacological Research, 24125 Bergamo, Italy
    Cancer Res 63:5224-9. 2003
    ..Levels of MMP9 (pro and activated form) and proMMP2 in ascites correlated with VEGF and with the ascitic volume in nude mice bearing human ovarian carcinoma xenografts (HOC22 ..
  3. ncbi Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer
    Yoko Hasumi
    Division of Genetic Therapeutics, Jichi Medical School, Tochigi 329 0498, Japan
    Cancer Res 62:2019-23. 2002
    ..and stimulating endothelial growth, is thought to be responsible for fluid accumulation and angiogenesis in ascites tumors...
  4. ncbi Guidelines on the management of ascites in cirrhosis
    K P Moore
    The UCL Institute of Hepatology, Royal Free and University College Medical School, UCL, Rowland Hill St, London NW3 2PF, UK
    Gut 55:vi1-12. 2006
  5. ncbi Proinflammatory and immunosuppressive serum, ascites and cyst fluid cytokines in patients with early and advanced ovarian cancer and benign ovarian tumors
    Marek Nowak
    Department of Gynecologic Surgery, Polish Mother s Memorial Hospital Research Institute, Poland
    Neuro Endocrinol Lett 31:375-83. 2010
    ..factor-beta1 (TGF-beta1) and interferon-gamma (IFN-gamma) in serum and the tumor microenvironment (cyst fluid, ascites) in women with ovarian cancer or benign ovarian tumors to find the differences in their immunological status...
  6. ncbi CXCL12 and vascular endothelial growth factor synergistically induce neoangiogenesis in human ovarian cancers
    Ilona Kryczek
    Tulane University Health Science Center, New Orleans, LA 70112, USA
    Cancer Res 65:465-72. 2005
    ..To examine tumor angiogenesis in the tumor microenvironment, we studied malignant ascites and tumors of patients with untreated ovarian carcinoma...
  7. ncbi Prognostic significance of interleukin 6 serum levels in patients with ovarian cancer
    G Scambia
    Department of Gynecology and Obstetrics, Catholic University, Rome, Italy
    Br J Cancer 71:354-6. 1995
    ..0009). Multivariate analysis revealed that IL-6 positivity has an independent value...
  8. ncbi Complete remission of ovarian cancer induced intractable malignant ascites with intraperitoneal bevacizumab. Immunological observations and a literature review
    Filippo Bellati
    Institute of Gynecology and Obstetrics, Sapienza University, Rome, Italy
    Invest New Drugs 28:887-94. 2010
    Malignant ascites resistant to conventional drugs frequently affects ovarian cancer patients at the end of life...
  9. ncbi The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
    Markus M Heiss
    Department of Surgery, Cologne Merheim Medical Center, University of Witten Herdecke, Cologne, Germany
    Int J Cancer 127:2209-21. 2010
    Malignant ascites is a common manifestation of advanced cancers, and treatment options are limited...
  10. ncbi Malignant ascites-derived exosomes of ovarian carcinoma patients contain CD24 and EpCAM
    Steffen Runz
    Tumor Immunology Programme D010, German Cancer Research Center, Im Neuenheimer Feld 580, D 69120 Heidelberg, Germany
    Gynecol Oncol 107:563-71. 2007
    ..Given the emerging role of exosomes in tumor progression, we investigated whether cytoplasmic CD24 expression is correlated with the secretion of CD24 in exosomes...
  11. ncbi Malignant ascites: past, present, and future
    Rony A Adam
    Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA 30303, USA
    J Am Coll Surg 198:999-1011. 2004
  12. ncbi A prospective evaluation of catheter probe EUS for the detection of ascites in patients with gastric carcinoma
    Kent-Man Chu
    Current affiliations: Division of Upper Gastrointestinal Surgery, Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, China
    Gastrointest Endosc 59:471-4. 2004
    ..This study assessed the value of EUS in the detection of ascites not visible on CT in patients with gastric carcinoma...
  13. ncbi Mining the ovarian cancer ascites proteome for potential ovarian cancer biomarkers
    Cynthia Kuk
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario M5G 1L5, Canada
    Mol Cell Proteomics 8:661-9. 2009
    ..We performed an in-depth proteomics analysis of ovarian cancer ascites fluid...
  14. ncbi Pharmacokinetics, micro-SPECT/CT imaging and therapeutic efficacy of (188)Re-DXR-liposome in C26 colon carcinoma ascites mice model
    Liang Cheng Chen
    Institute of Nuclear Energy Research, Taoyuan, Taiwan
    Nucl Med Biol 35:883-93. 2008
    ..pegylated liposomal doxorubicin ((188)Re-DXR-liposome) were investigated in the C26 murine colon carcinoma ascites mouse model...
  15. ncbi [Eosinophilic enteritis as a rare cause of ascites]
    A Bouhmidi

    Gastroenterol Hepatol 26:480-1. 2003
    ..depend on the affected layers and range from barely perceptible symptoms to intestinal obstruction or ascites. We present the case of an 18-year-old woman who showed abdominal ascites as a rare form of presentation with ..
  16. ncbi Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity
    Robert L Giuntoli
    The Kelly Gynecologic Oncology Service, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Phipps 281, Baltimore, Maryland 21287, USA
    Anticancer Res 29:2875-84. 2009
    To identify immunosuppressive elements present in ovarian cancer associated ascites.
  17. ncbi Involvement of M2-polarized macrophages in the ascites from advanced epithelial ovarian carcinoma in tumor progression via Stat3 activation
    Kiyomi Takaishi
    Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Cancer Sci 101:2128-36. 2010
    b>Ascites macrophages in advanced epithelial ovarian cancer (AdEOC) are involved in cancer metastasis and progression by modifying the tumor microenvironment...
  18. ncbi Continuous docetaxel chemotherapy improves therapeutic efficacy in murine models of ovarian cancer
    Raquel De Souza
    Department of Pharmaceutical Sciences, University of Toronto, Ontario, Canada
    Mol Cancer Ther 9:1820-30. 2010
    ..is considerably more efficacious than intermittent therapy, resulting in a greater decrease in tumor burden and ascites fluid accumulation...
  19. ncbi Preparation of human ovarian cancer ascites-derived exosomes for a clinical trial
    H Navabi
    Cancer Services, Velindre NHS Trust, Cardiff, UK
    Blood Cells Mol Dis 35:149-52. 2005
    ..undergoing chemotherapy using a combination of a Toll-like receptor 3 (TLR3) agonist and tumour-associated ascites-derived exosomes...
  20. ncbi IL-6 trans-signaling in formation and progression of malignant ascites in ovarian cancer
    Chi Wen Lo
    Department of Oncology, National Taiwan University Hospital, Institute of Toxicology, National Taiwan University College of Medicine, Nankang, Taiwan
    Cancer Res 71:424-34. 2011
    ..Here we report that sIL-6Rα is elevated in malignant ascites from ovarian cancer patients, where it is associated with poor prognosis...
  21. ncbi Rapid growth problems: ascites and skeletal deformities in broilers
    R J Julian
    Department of Pathology, Ontario Veterinary College, University of Guelph, Canada
    Poult Sci 77:1773-80. 1998
    ..In the chicken, sudden death syndrome (flip-over) and pulmonary hypertension syndrome resulting in ascites are the most important...
  22. ncbi Ovarian cancer ascites protects from TRAIL-induced cell death through alphavbeta5 integrin-mediated focal adhesion kinase and Akt activation
    D Lane
    Departement De Microbiologie et Infectiologie, Faculte de Medecine, Universite de Sherbrooke, Sherbrooke, Canada
    Oncogene 29:3519-31. 2010
    ..We have earlier shown that ovarian cancer ascites induces Akt activation and protect tumor cells from TRAIL-induced apoptosis...
  23. ncbi Cytoreductive surgery plus hyperthermic intraperitoneal chemotherapy to treat gastric cancer with ascites and/or peritoneal carcinomatosis: Results from a Chinese center
    Xiao jun Yang
    Department of Oncology, Zhongnan Hospital Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors and Hubei Cancer Clinical Study Center, Wuchang District, Wuhan, Hubei Province, China
    J Surg Oncol 101:457-64. 2010
    ..This work was to evaluate cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) for advanced gastric cancer (GC)...
  24. ncbi Ascites as a predictor of ovarian malignancy
    Jane Shen-Gunther
    Gynecologic Surgery and Oncology, 2911 N Tenaya Way, Suite 105, Las Vegas, NV 89128, USA
    Gynecol Oncol 87:77-83. 2002
    To determine the utility of ascites as a predictor of ovarian malignancy and define its relationship with the histologic type of ovarian tumor (benign, borderline, or malignant) and stage of disease.
  25. ncbi HLA-G is a potential tumor marker in malignant ascites
    Gad Singer
    Department of Pathology, Johns Hopkins University Medical Institutions, Baltimore Maryland 21231, USA
    Clin Cancer Res 9:4460-4. 2003
    PURPOSE: Molecular approaches as supplements to cytological examination of malignant ascites may play an important role in the clinical management of cancer patients...
  26. ncbi VEGF expression and the effect of NSAIDs on ascites cell proliferation in the hen model of ovarian cancer
    M E Urick
    Department of Animal Science, Cornell University, Ithaca, NY 14853, USA
    Gynecol Oncol 110:418-24. 2008
    We aimed to determine the expression of vascular endothelial growth factor (VEGF) and the effect of nonsteroidal anti-inflammatory drugs (NSAIDs) on the proliferation of cells isolated from ascites in the hen model of ovarian cancer.
  27. ncbi Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer
    Shengming Dai
    Department of Oncology, Institute of Clinical Medicine, The Fourth Hospital Affiliated to Guangxi Medical University, Liuzhou, People s Republic of China
    Mol Ther 16:782-90. 2008
    ..In this study we report the phase I clinical trial of the ascites-derived exosomes (Aex) in combination with the granulocyte-macrophage colony-stimulating factor (GM-CSF) in the ..
  28. ncbi Ovarian carcinoma ascites spheroids adhere to extracellular matrix components and mesothelial cell monolayers
    Kathryn M Burleson
    Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
    Gynecol Oncol 93:170-81. 2004
    ..The current paradigm that ascites spheroids are non-adhesive leaves their contribution to ovarian carcinoma dissemination undefined...
  29. ncbi A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascites
    M Rossle
    Medizinische Klinik II, Albrecht Ludwigs Universität, Department of Gastroenterology, Freiburg, Germany
    N Engl J Med 342:1701-7. 2000
    In patients with cirrhosis and ascites, creation of a transjugular intrahepatic portosystemic shunt may reduce the ascites and improve renal function...
  30. ncbi Malignant ascites: systematic review and guideline for treatment
    Gerhild Becker
    Department of Internal Medicine II, University Hospital of Freiburg, Hugstetter Str 55, D 79106 Freiburg, Germany
    Eur J Cancer 42:589-97. 2006
    A guideline on the management of symptomatic malignant ascites by abdominal paracentesis, diuretics and peritoneovenous shunting, based on a systematic review of the literature is presented. Thirty-two relevant studies were identified...
  31. ncbi Ascitic fluid infection in patients with hepatitis B virus-related liver cirrhosis: culture-negative neutrocytic ascites versus spontaneous bacterial peritonitis
    Seung Up Kim
    Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
    J Gastroenterol Hepatol 25:122-8. 2010
    Ascitic fluid infection (AFI) consists of culture-negative neutrocytic ascites (CNNA) and spontaneous bacterial peritonitis (SBP)...
  32. ncbi Albendazole: a potent inhibitor of vascular endothelial growth factor and malignant ascites formation in OVCAR-3 tumor-bearing nude mice
    Mohammad Hossein Pourgholami
    Cancer Research Laboratories, Department of Surgery, St. George Hospital, University of New South Wales, Sydney, New South Wales, Australia
    Clin Cancer Res 12:1928-35. 2006
    PURPOSE: Angiogenesis and vessel hyperpermeability are the two factors leading to the formation of ascites. Vascular endothelial growth factor (VEGF) plays a pivotal role in malignant ascites formation...
  33. ncbi Ascites and spontaneous bacterial peritonitis: an Asian perspective
    Jung Min Lee
    Department of Internal Medicine, Brain Korea 21 Project for Medical Science, Seoul, South Korea
    J Gastroenterol Hepatol 24:1494-503. 2009
    b>Ascites is the most common complication of liver cirrhosis, and it develops as a consequence of portal hypertension and splanchnic vasodilatation...
  34. ncbi The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation
    Carlos Guarner
    Liver Section, , Hospital de la Sta. Creu i St. Pau, Barcelona, and Liver Unit, Hospital General Universitario, Alicante, Spain
    Hepatology 44:633-9. 2006
    Bacterial DNA (bactDNA) is present in blood and ascitic fluid (AF) in a third of patients with cirrhosis and ascites, but whether this phenomenon represents episodes of bacterial translocation (BT), strictly considered when culture of ..
  35. ncbi Proinvasive properties of ovarian cancer ascites-derived membrane vesicles
    Laura E Graves
    Department of Cellular and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA
    Cancer Res 64:7045-9. 2004
    Malignant ovarian ascites are rich in cellular components, membrane-bound vesicles, and soluble proteins...
  36. ncbi Ultrasonography in the diagnosis and monitoring of ascites in acute abdominal attacks of hereditary angioneurotic oedema
    H Farkas
    Kutvolgyi Clinical Centre, Allergology and Angio oedema Outpatient Clinic, Semmelweis University, Budapest, Hungary
    Eur J Gastroenterol Hepatol 13:1225-30. 2001
    Hereditary angioneurotic oedema (HAE) is a rare cause of ascites. As acute abdominal attacks of the disease can mimic surgical emergencies, prompt and accurate diagnosis is essential...
  37. ncbi Cholesterol metabolism during the growth of a rat ascites hepatoma (Yoshida AH-130)
    S Dessi
    Istituto di Patologia Sperimentale, Universita degli Studi di Cagliari, Italy
    Br J Cancer 66:787-93. 1992
    ..of cholesterol has been investigated in tumour cells, ascitic fluid and blood serum during the growth of an ascites hepatoma (Yoshida AH-130) in the rat...
  38. ncbi A sequential study of serum bacterial DNA in patients with advanced cirrhosis and ascites
    Rubén Francés
    Unidad Hepática Sección de Inmunología, Alicante, Spain
    Hepatology 39:484-91. 2004
    ..main pathogenic mechanism leading to spontaneous bacterial peritonitis in patients with advanced cirrhosis and ascites. However, to the authors' knowledge there is no information regarding the characteristics of this process in ..
  39. ncbi Vascular endothelial growth factor immunoneutralization plus Paclitaxel markedly reduces tumor burden and ascites in athymic mouse model of ovarian cancer
    Limin Hu
    Center for Reproductive Sciences, University of California at San Francisco 94143, USA
    Am J Pathol 161:1917-24. 2002
    Ovarian cancer is characterized by rapid growth of solid intraperitoneal tumors and production of large volumes of ascites. Our previous studies of intraperitoneal ovarian carcinoma in an athymic mouse model demonstrated that a ..
  40. ncbi Patients with ovarian cancer have elevated (51)Cr-EDTA plasma clearance early post-operatively
    S S Nielsen
    Department of Clinical Physiology and Nuclear Medicine, Skejby Sygehus, Aarhus University Hospital, Brendstrupgaardsvej, DK 8200 Aarhus N, Denmark
    Nucl Med Commun 23:917-20. 2002
    ..Additionally, age, height, weight, cancer stage, ascites and tumour histology were noted...
  41. ncbi A phase II study of aflibercept in patients with advanced epithelial ovarian cancer and symptomatic malignant ascites
    Nicoletta Colombo
    Istituto Europeo di Oncologia, Divisione di Ginecologia, Via Ripamonti, Milano, Italy
    Gynecol Oncol 125:42-7. 2012
    ..Aflibercept inhibits ascites formation and reduces tumor burden in an ovarian cancer model...
  42. ncbi Effect of ascites on bone density measurement in cirrhosis
    Eternity D Labio
    NHMRC Center of Clinical Research Excellence to Improve Outcome in Chronic Liver Disease, AW Morrow Gastroenterology and Liver Center, University of Sydney, Camperdown, New South Wales, Australia
    J Clin Densitom 10:391-4. 2007
    Cirrhosis is an independent risk factor for the development of osteoporosis. The presence of ascites in patients with cirrhosis may affect the accuracy of bone density measurement in the spine...
  43. ncbi Determination of the necessary total protein substitution requirements in patients with advanced stage ovarian cancer and ascites, undergoing debulking surgery. Correlation with plasma proteins
    George Vorgias
    Department of Gynecology, Metaxa Memorial Cancer Hospital, Piraeus, Greece
    Ann Surg Oncol 14:1919-23. 2007
    b>Ascites is common in patients with advanced ovarian carcinoma (AOC). Its drainage during surgery affects plasma proteins...
  44. ncbi Effect of cold stress on broilers selected for resistance or susceptibility to ascites syndrome
    J M Balog
    USDA ARS PP and PSR, Fayetteville, Arkansas 72701, USA
    Poult Sci 82:1383-7. 2003
    Genetic selection for an ascites-resistant line of broilers is seen as a permanent solution to the ascites problem...
  45. ncbi Spontaneous ovarian hyperstimulation syndrome in a normal singleton pregnancy
    Ozer Oztekin
    Department of Obstetrics and Gynecology, Faculty of Medicine, Pamukkale University, Denizli, Turkey
    Taiwan J Obstet Gynecol 45:272-5. 2006
    ..However, OHSS may rarely be associated with a spontaneous ovulatory cycle, usually in the case of multiple gestations, hypothyroidism or polycystic ovary syndrome...
  46. ncbi Torsion of a giant omental cyst mimicking ascites
    Suat Fitoz
    Department of Radiology, Ankara University School of Medicine, Dikimevi, Ankara 06100, Turkey
    J Clin Ultrasound 35:85-7. 2007
    ..The cyst occupied nearly the whole abdomen and mimicked massive ascites on sonography...
  47. ncbi Ascites syndrome in broilers: physiological and nutritional perspectives
    A Baghbanzadeh
    Section of Physiology, Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran
    Avian Pathol 37:117-26. 2008
    ..If this is not done, inefficient production and several metabolic diseases such as ascites become apparent...
  48. ncbi Evaluation of minimally invasive indices for predicting ascites susceptibility in three successive hatches of broilers exposed to cool temperatures
    R F Wideman
    Department of Poultry Science, University of Arkansas, Fayetteville 72701, USA
    Poult Sci 77:1565-73. 1998
    ..hatches were exposed to cool temperatures to amplify the incidence of pulmonary hypertension syndrome (PHS, ascites)...
  49. ncbi Coexistence of struma ovarii with marked ascites and elevated CA-125 levels: case report and literature review
    Mabel Po Mui
    Department of Obstetrics and Gynaecology, Centro Hospitalar Conde de S Januario, Macao, People s Republic of China
    Arch Gynecol Obstet 279:753-7. 2009
    Struma ovarii is a rare form of ovarian neoplasm and consists mainly of thyroid tissue. Ascites has been reported in approximately one-third of all the cases...
  50. ncbi Laparoscopic hyperthermic intraperitoneal peroperative chemotherapy (HIPEC) in the management of refractory malignant ascites: A multi-institutional retrospective analysis in 52 patients
    M Valle
    Department of Surgical Oncology, Digestive Branch, Regina Elena National Cancer Institute, Rome, Italy
    J Surg Oncol 100:331-4. 2009
    Malignant ascites is a debilitating condition affecting cancer patients in their terminal stage of disease. Recently, laparoscopic hyperthermic intraperitoneal peroperative chemotherapy (HIPEC) was introduced as a new approach...
  51. ncbi Interferon-gamma release assay in the ascites: Early hint for diagnosis of abdominal tuberculosis
    R Lorenz
    Dept of Internal Medicine, University Hospital Ulm, Germany
    Infection 38:69-72. 2010
    We report on a 20-year-old woman with abdominal tuberculosis.Standard microbiological examination of ascites showed no acid-fast bacilli (AFB), and analysis for the Mycobacterium tuberculosis (MTB)-complex DNA by PCR was negative...
  52. ncbi Antitumor activity of silver nanoparticles in Dalton's lymphoma ascites tumor model
    Muthu Irulappan Sriram
    Department of Biotechnology, Division of Molecular and Cellular Biology, Kalasalingam University, Tamilnadu, India
    Int J Nanomedicine 5:753-62. 2010
    ..efficacy of biologically synthesized silver nanoparticles (AgNPs) as an antitumor agent using Dalton's lymphoma ascites (DLA) cell lines in vitro and in vivo...
  53. ncbi Risk of complications after abdominal paracentesis in cirrhotic patients: a prospective study
    Andrea De Gottardi
    Division of Gastroenterology and Hepatology, University Hospital of Geneva, Geneva, Switzerland
    Clin Gastroenterol Hepatol 7:906-9. 2009
    ..Complications and technical problems of paracentesis in cirrhotic patients are infrequent. However, the severity and the incidence of these events and their risk factors have not been assessed prospectively...
  54. ncbi Chemotherapy with laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion for malignant ascites
    Ming Chen Ba
    Department of Abdominal Surgery Section 2, Cancer Hospital of Guangzhou Medical College, Guangzhou 510095, Guangdong Province, China
    World J Gastroenterol 16:1901-7. 2010
    ..procedure, feasibility and effects of laparoscope-assisted continuous circulatory hyperthermic intraperitoneal perfusion chemotherapy (CHIPC) in treatment of malignant ascites induced by peritoneal carcinomatosis from gastric cancers.
  55. ncbi Secondary Aeromonas peritonitis is associated with polymicrobial ascites culture and absence of liver cirrhosis compared to primary Aeromonas peritonitis
    Ling-Ju Huang
    Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    APMIS 114:772-8. 2006
    ..011). A source of intraabdominal infection should be sought when Aeromonas peritonitis occurs in a patient who has no history of liver cirrhosis or who has a polymicrobial result of ascites culture.
  56. ncbi TIPS for the treatment of refractory ascites, hepatorenal syndrome and hepatic hydrothorax: a critical update
    Martin Rossle
    Praxiszentrum, Bertoldstrasse 48, Freiburg, Germany
    Gut 59:988-1000. 2010
    Refractory ascites is a frequent complication of advanced cirrhosis and is associated with hepatorenal syndrome and hepatic hydrothorax...
  57. ncbi An ovarian steroid cell tumor causing virilization and massive ascites
    Young Tae Kim
    Department of Obstetrics and Gynecology, Yonsei University College of Medicine, 135 Shinchon dong Seodaemun gu, Seoul 120 752, Korea
    Yonsei Med J 48:142-6. 2007
    ..symptoms such as hirsutism, temporal balding, and amenorrhea are common in these patients; however massive ascites is an infrequent symptom...
  58. ncbi Concurrent aspergillosis and ascites with high mortality in a farm of growing broiler chickens
    R Zafra
    Department of Anatomy and Comparative Pathology, Infectious Diseases Unit, Faculty of Veterinary Medicine, Campus de Rabanales, Ctra Madrid Cadiz km 396, 14014 Cordoba, Spain
    Avian Dis 52:711-3. 2008
    ..At necropsy, severe ascites, right heart hypertrophy, pulmonary congestion, and extensive multifocal granulomatous pneumonia were recorded...
  59. ncbi [Refractory ascites in hemodialysis: treatment by paracentesis- reinjection during dialysis]
    M Touam
    Service de néphrologie et INSERM U 507, Hopital Necker, Paris
    Nephrologie 22:25-8. 2001
    ..patients, one male and one female, aged 46 and 54 years, were treated with preceed respectively for refractory ascites secondary to hepatic cirrhosis and for large polycystic liver...
  60. ncbi Cyclic AMP-phosphodiesterases inhibitor improves sodium excretion in rats with cirrhosis and ascites
    Mina Ahloulay
    , INSERM U-481, , 92118 Clichy, France
    Liver Int 25:403-9. 2005
    ..Renal function was studied by the clearance technique in anesthetized control and cirrhotic rats with or without ascites. cAMP phosphodiesterase (PDE) activity was measured in the renal cortex in vitro...
  61. ncbi Peritoneovenous shunting for nongynecologic malignant ascites
    S C Bieligk
    Department of Surgery, Division of Surgical Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA
    Cancer 91:1247-55. 2001
    BACKGROUND: The development of malignant ascites has been associated with a poor prognosis. Previous reports have documented high morbidity rates associated with placement of palliative peritoneovenous shunts (PVS)...
  62. ncbi A novel technique to treat ruptured umbilical hernias in patients with liver cirrhosis and severe ascites
    Marc L Melcher
    Stanford University School of Medicine, Palo Alto, California 94304, USA
    J Laparoendosc Adv Surg Tech A 13:331-2. 2003
    ..Here, we present a case report of the use of a novel technique to treat a patient with this condition. The use of a fibrin-based tissue adhesive provides a means of managing such patients medically...
  63. ncbi Doxorubicin levels in the serum and ascites of patients with ovarian cancer
    W H Gotlieb
    Division of Gynecologic Oncology, Jewish General Hospital, McGill University, 3755 Cote Ste Catherine, Suite A 632, Montreal, QC H3T 1E2, Canada
    Eur J Surg Oncol 33:213-5. 2007
    To investigate the diffusion and accumulation of doxorubicin metabolites in the ascites of patients with ovarian cancer following intravenous injection, as a model for intraperitoneal accumulation of drugs.
  64. ncbi Uncovered transjugular intrahepatic portosystemic shunt for refractory ascites: a meta-analysis
    Gennaro D'Amico
    Unit of Gastroenterology, Ospedale V Cervello, Palermo, Italy
    Gastroenterology 129:1282-93. 2005
    ..transjugular intrahepatic portosystemic shunt (TIPS) is superior to paracentesis for the control of refractory ascites. However, the results for encephalopathy and mortality were not consistent across trials...
  65. ncbi Paracrine action of sFLT-1 secreted by stably-transfected Ehrlich ascites tumor cells and therapy using sFLT-1 inhibits ascites tumor growth in vivo
    Sunitha Ramachandra
    Department of Studies in Biotechnology, University of Mysore, Mysore, 570006 Karanataka, India
    J Gene Med 11:422-34. 2009
    ..In the present study, we have developed and tested strategies targeted specifically to VEGF for the treatment of ascites formation.
  66. ncbi Percutaneous radiofrequency ablation of hepatocellular carcinoma abutting the diaphragm and gastrointestinal tracts with the use of artificial ascites: safety and technical efficacy in 143 patients
    Inyoung Song
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul 135 710, Korea
    Eur Radiol 19:2630-40. 2009
    ..was to assess the feasibility, safety and efficacy of radiofrequency ablation (RFA) with the use of artificial ascites for hepatocellular carcinoma (HCC) adjacent to the diaphragm and gastrointestinal tract...
  67. ncbi Comparison of percutaneous management techniques for recurrent malignant ascites
    Stefanie Rosenberg
    Department of Radiology, Northwestern University, Evanston Hospital, 2650 Ridge Avenue, Evanston, IL 60201, USA
    J Vasc Interv Radiol 15:1129-31. 2004
    ..drainage of malignant pleural effusions; however, there is limited literature describing its use in malignant ascites. The authors compared the safety and efficacy of two percutaneous drainage methods: large volume paracentesis and ..
  68. ncbi Hepatic hydrothorax in the absence of ascites: respiratory failure in a cirrhotic patient
    Jordi Serrat
    Servei d Anestesiologia i Reanimació, Hospital General de Vic, C Francesc Pla s n, 08500 Vic, Barcelona, Spain
    Anesth Analg 99:1803-4, table of contents. 2004
    ..Although most often accompanied by significant ascites, it can occur in its absence...
  69. ncbi Ascites due to right atrial myxoma in a haemodialysis patient
    Anindya Banerjee
    University College London, Centre for Nephrology, Royal Free Hospital, London, UK
    BMC Nephrol 7:4. 2006
    ..Persistent fluid overload in patients on renal replacement therapy despite good dialysis adequacy or obvious cardiac dysfunction should prompt a search for rarer causes...
  70. ncbi Ascites reinfusion dialysis (ARD) for renal failure with refractory ascites
    R L McGill
    Division of Nephrology and Hypertension, West Penn Allegheny Health System, Allegheny General Hospital, Pittsburgh, PA 15212, USA
    Clin Nephrol 62:374-9. 2004
    Dialysis is difficult for patients who have simultaneous liver and kidney failure. Effective mobilization of ascites is rare, and hypotension is common...
  71. ncbi TIPS versus peritoneovenous shunt in the treatment of medically intractable ascites: a prospective randomized trial
    Alexander S Rosemurgy
    Department of Surgery, University of South Florida, Tampa, Florida, USA
    Ann Surg 239:883-9; discussion 889-91. 2004
    ..a prospective randomized clinical trial comparing TIPS to peritoneovenous (PV) shunts in the treatment of medically intractable ascites to establish relative efficacy and morbidity, and thereby superiority, between these shunts.
  72. ncbi Prostate cancer with metastasis to the omentum and massive ascites: a rare manifestation of a common disease
    Flora Zagouri
    Department of Clinical Therapeutics, Athens University, School of Medicine, Athens, Greece
    Onkologie 32:758-61. 2009
    ..The most common sites of metastasis in prostate cancer include bone and regional lymph nodes followed by lung, liver, and brain. Peritoneal metastasis without skeletal involvement is extremely rare...
  73. ncbi Eosinophilic ascites in a patient with toxocara canis infection. A case report
    Olimpia Chira
    3rd Medical Clinic, and University of Medicine and Pharmacy, Cluj Napoca, Romania
    Rom J Gastroenterol 14:397-400. 2005
    We report the case of a young female patient, admitted for a recent ascites of unknown origin. The acute onset was with colicky abdominal pain and peritoneal effusion, which led to the suspicion of perforated ulcer...
  74. ncbi Clinical and diagnostic significance of preoperative computed tomography findings of ascites in patients with advanced gastric cancer
    Kazuhito Yajima
    Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences, Japan
    Am J Surg 192:185-90. 2006
    BACKGROUND: The relationship between ascites, as detected by preoperative computed tomography (CT), and peritoneal metastasis of gastric cancer requires clarification because of its likely significance for clinical outcome...
  75. ncbi Umbilical hernia repair in the presence of cirrhosis and ascites: results of a survey and review of the literature
    A McKay
    Department of Surgery, Health Sciences Centre, University of Manitoba, GF 441, 820 Sherbrook St, Winnipeg, MB R3A 1R9, Canada
    Hernia 13:461-8. 2009
    ..The objective of this paper was to evaluate the indications, selection criteria, and technical aspects of umbilical hernia repair in patients with cirrhosis and ascites.
  76. ncbi Risk factors and management of ascites after liver resection to treat hepatocellular carcinoma
    Takeaki Ishizawa
    Hepato Biliary Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655, Japan
    Arch Surg 144:46-51. 2009
    To identify risk factors for a massive amount of ascites after liver resection to treat hepatocellular carcinoma and to evaluate our postoperative management strategy.
  77. ncbi Portopulmonary hypertension in decompensated cirrhosis with refractory ascites
    F S Benjaminov
    Division of Gastroenterology, Toronto General Hospital, University of Toronto, Toronto, Ontario, Canada
    Gut 52:1355-62. 2003
    BACKGROUND: The prevalence of portopulmonary hypertension (PPHTN) in patients with cirrhosis and refractory ascites is unknown...
  78. ncbi The management of ascites and hyponatremia in cirrhosis
    Pere Gines
    Liver Unit, Hospital Clinic and University of Barcelona, Institut d Investigacions Biomèdiques August Pi Sunyer, Ciber de Enfermedades Hepaticas y Digestivas, Barcelona, Spain
    Semin Liver Dis 28:43-58. 2008
    b>Ascites is the most common complication of cirrhosis and is associated with an increased risk for the development of infections, dilutional hyponatremia, renal failure, and mortality...
  79. ncbi Percutaneous peritoneovenous shunt for treatment of refractory ascites
    Jong Yun Won
    Departments of Radiology, Yonsei University College of Medicine, 134 Shinchon dong, Seodaemun gu, 120 752, Seoul, Korea
    J Vasc Interv Radiol 19:1717-22. 2008
    To evaluate the usefulness of a percutaneously placed peritoneovenous shunt (PVS) in patients with refractory ascites.
  80. ncbi Renal resistive index and renal function before and after paracentesis in patients with hepatorenal syndrome and tense ascites
    Andreas Umgelter
    II Medizinische Klinik und Poliklinik, Klinikum rechts der Isar, Ismaninger Str 22, 81675, Munich, Germany
    Intensive Care Med 35:152-6. 2009
    ..To assess the effect of reducing intra-abdominal pressure (IAP) by paracentesis on renal resistive index (RI), hemodynamics and renal function...
  81. ncbi Sonographically guided peritoneal catheter placement in the palliation of malignant ascites in end-stage malignancies
    Sergio Sartori
    Department of Internal Medicine, Section of Interventional Ultrasound, St. Anna Hospital, 44100 Ferrara, Italy
    AJR Am J Roentgenol 179:1618-20. 2002
  82. ncbi Inhibitory effect of Abrus abrin-derived peptide fraction against Dalton's lymphoma ascites model
    Sujit K Bhutia
    Department of Biotechnology, Indian Institute of Technology, Kharagpur 721302, West Bengal, India
    Phytomedicine 16:377-85. 2009
    ..Kaplan-Meier survival analysis showed an effective antitumor response (104.6 increase in life span (ILS) %) with a dose of 100 microg/kg body weight...
  83. ncbi The effect of ascites, mass volume, and peritoneal carcinomatosis on serum CA125 levels in patients with ovarian carcinoma
    U Saygili
    Department of Obstetrics and Gynecology, Dokuz Eylul University School of Medicine, Izmir, Turkey
    Int J Gynecol Cancer 12:438-42. 2002
    The aim of this study is to investigate the effects of ascites, ovarian mass volume, and peritoneal carcinomatosis on serum CA125 levels in patients with nonmucinous epithelial ovarian carcinoma...
  84. ncbi Preoperative staging of gastric cancer by endoscopic ultrasound: the prognostic usefulness of ascites detected by endoscopic ultrasound
    Chien-Hua Chen
    Division of Gastroenterology, Department of Internal Medicine, Changhua Show-Chwan Memorial Hospital, Changua, Taiwan
    J Clin Gastroenterol 35:321-7. 2002
    ..EUS) is the standard modality in local preoperative staging of gastric cancers and is reputedly able to detect ascites. However, the association between ascites detected by EUS and local tumor staging, peritoneal carcinomatosis, or ..
  85. ncbi Increased expression of dipeptidyl peptidase IV in human mesothelial cells by malignant ascites from ovarian carcinoma patients
    H Kajiyama
    Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Nagoya, Japan
    Oncology 63:158-65. 2002
    ..There are many bioactive peptides in ascites and these peptides are involved in carcinoma cell dissemination and infiltration...
  86. ncbi Ruptured umbilical hernia in a case of alcoholic cirrhosis with massive ascites
    Jacqueline Granese
    Seton Hall University Surgical Residency Program at St. Francis Medical Center, Trenton, New Jersey 08629, USA
    Am Surg 68:733-4. 2002
    Umbilical hernias are common in patients with cirrhosis of the liver and ascites. However, spontaneous rupture of the hernia is not frequently seen. This is a serious complication and carries a high mortality...
  87. ncbi Toxocariasis causing eosinophilic ascites
    Andrea T Cruz
    Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA
    Pediatr Infect Dis J 27:563-4. 2008
    Eosinophilic ascites in the absence of gastroenteritis is uncommon in children. We report the case of a 13-year-old girl with eosinophilic ascites caused by Toxocara, only the second reported case in the literature...
  88. ncbi Palliative treatment of malignant refractory ascites by positioning of Denver peritoneovenous shunt
    Claudio Zanon
    Dipartimento di Oncologia, Azienda Ospedaliera San Giovanni Battista, Torino, Italy
    Tumori 88:123-7. 2002
    Malignant ascites is relatively common in patients with certain types of end-stage cancer. Traditional treatments based on fluid and salt restriction and diuretic therapy often are not able to contain neoplastic ascites...
  89. ncbi Accuracy of endoscopic ultrasonography in diagnosing ascites and predicting peritoneal metastases in gastric cancer patients
    Y T Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin NT, Hong Kong, China
    Gut 54:1541-5. 2005
    ..Preoperative diagnosis of peritoneal metastases (PM) is difficult in patients with gastric cancer (GC)...
  90. ncbi Neonatal urinary ascites secondary to urinary bladder rupture
    Nikhil Vasdev
    Department of Pediatric Urology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, UK
    J Pediatr Urol 5:100-4. 2009
    ..radiology and clinical management of four neonates with spontaneous urinary bladder rupture and secondary urinary ascites seen in 1984 and two recent cases seen in 2007...
  91. ncbi Improved quality of life in patients with refractory or recidivant ascites after insertion of transjugular intrahepatic portosystemic shunts
    Veit Gulberg
    Department of Medicine II, Klinikum of the University of Munich Grosshadern, Germany
    Digestion 66:127-30. 2002
    ..portosystemic shunt (TIPS) is more effective than paracentesis in the treatment of cirrhotic patients with severe ascites and can prolong survival in selected patients...
  92. ncbi Effects of dietary L-carnitine and coenzyme Q10 at different supplemental ages on growth performance and some immune response in ascites-susceptible broilers
    Ailian Geng
    College of Animal Science and Technology, The State Key Lab of Animal Nutrition, China Agricultural University, Beijing, PR China
    Arch Anim Nutr 61:50-60. 2007
    ..coenzyme Q10 (CoQ10) at different supplemental ages on performance and some immune response were investigated in ascites-susceptible broilers...
  93. ncbi Long-term efficacy of torsemide compared with frusemide in cirrhotic patients with ascites
    R Abecasis
    Liver Unit, Hospital de Gastroenterología Dr B Udaondo, Universidad del Salvador, School of Medicine, Buenos Aires, Argentina
    Scand J Gastroenterol 36:309-13. 2001
    ..However, torsemide long-term effects and complications have not been sufficiently investigated. The aim was to compare the efficacy and safety of torsemide versus frusemide in cirrhotic patients with uncomplicated ascites.
  94. ncbi Fetal urinary bladder rupture and urinary ascites secondary to posterior urethral valves. A case report
    M Lacher
    Kinderchirurgische Klinik im Dr von Haunerschen Kinderspital, Munchen, Germany
    Eur J Pediatr Surg 17:217-20. 2007
    ..We report on a boy with in utero bladder perforation and urinary ascites secondary to posterior urethral valves...
  95. ncbi Weekly Paclitaxel after failure of gemcitabine in pancreatic cancer patients with malignant ascites: a retrospective study
    Takehito Shukuya
    Division of Gastrointestinal Oncology, Shizuoka Cancer Center, 1007, Nagaizumi, Shizuoka 411 8777, Japan
    Jpn J Clin Oncol 40:1135-8. 2010
    ..be candidates for chemotherapy after failure in the first-line chemotherapy, especially those with malignant ascites. The safety and efficacy of weekly paclitaxel therapy was evaluated for pancreatic cancer patients with malignant ..
  96. ncbi Phyllanthus amarus inhibits cell growth and induces apoptosis in Dalton's lymphoma ascites cells through activation of caspase-3 and downregulation of Bcl-2
    Kuzhuvelil B Harikumar
    Amala Cancer Research Centre, Amala Nagar, Thrissur, Kerala, India com
    Integr Cancer Ther 8:190-4. 2009
    The authors found in an earlier study that Phyllanthus amarus extract could significantly inhibit the solid and ascites tumor development in mice induced by Dalton's lymphoma ascites (DLA) cells...
  97. ncbi Lymphoma presenting as peritoneal lymphomatosis with ascites
    Shuo Chun Weng
    Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan, R O C
    J Chin Med Assoc 71:646-50. 2008
    ..woman was diagnosed with disseminated peritoneal lymphoma with gastric and rectal involvement and marked ascites. Flow cytometry of the surface markers for ascites showed positive results for CD19, CD20 and CD45...
  98. ncbi [Transjugular intrahepatic portosystemic stent-shunts or paracentesis in the treatment of cirrhotic patients with refractory ascites]
    Mark A Ainsworth
    Amtssygehuset i Herlev, Medicinsk Gastroenterologisk Afdeling C, Herlev
    Ugeskr Laeger 167:3273-6. 2005
  99. ncbi [Diagnosis of spontaneous ascites infection in patients with cirrhosis: reagent strips]
    B Wisniewski
    Service d Hepatogastroenterologie, Centre Hospitalier Sud Francilien, quartier du Canal Courcouronnes, 91014 Evry Cedex
    Presse Med 34:997-1000. 2005
    ..the sensitivity, specificity, and predictive values of dipstick testing (DT) for detecting spontaneous bacterial peritonitis (SBP), defined by an ascites neutrophil polymorphonuclear cell count > or = 250/mm3, in patients with cirrhosis.
  100. ncbi Management of refractory ascites
    Andres Cardenas
    Liver Unit, Institute of Digestive Diseases, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Clin Gastroenterol Hepatol 3:1187-91. 2005
  101. ncbi Portal hypertension
    Guadalupe Garcia-Tsao
    Section of Digestive Diseases, Yale University School of Medicine and Connecticut VA, Healthcare System, New Haven, 06510, USA
    Curr Opin Gastroenterol 22:254-62. 2006
    ..Significant advances in the pathophysiology, diagnosis and management of the complications of portal hypertension that have occurred in the last year are reported...

Research Grants77

  1. Molecular mechanism of antiangiogenic properties of gold nanoparticle
    Priyabrata Mukherjee; Fiscal Year: 2010
    ..It is likely that it will bind to all the pro-angiogenic heparin-binding growth factors present in the ascites and inhibit their function...
  2. ESOPHAGEAL VARICES BY B-ADRENERGIC BLOCKERS
    Roberto Groszmann; Fiscal Year: 2003
    ..but because it may prevent or delay the development of other complications of portal hypertension, such a ascites. This ongoing multi-center, prospective, randomized, placebo-controlled, double-blind trial was designed with the ..
  3. Identification of pancreatic cancer specific high affinity targeting ligands
    PAPPANAICKEN KUMARESAN; Fiscal Year: 2007
    ..can be used for imaging and to trap circulating cancer cells in the biological fluids such as blood, pancreatic ascites and stool...
  4. STRUCTURE/BIOSYNTHESIS OF TUMOR SIALOMUCIN COMPLEX
    KERMIT CARRAWAY; Fiscal Year: 1999
    ..is focused on a novel cell surface glycoprotein complex (sialomucin complex, SMC), originally isolated from ascites sublines of the highly metastatic 13762 rat mammary adenocarcinoma...
  5. Regulation of Ovarian Cancer Multidrug Resistance by MAP Kinases
    Scott T Eblen; Fiscal Year: 2010
    ..We generated phospho-specific antibodies and have shown SPF45 phosphorylation in human ascites and in cell lines in response to chemotherapeutic drugs, oxidative stress, phorbol esters and UV irradiation...
  6. PREVENTION OF ESOPHAGEAL VARICES BY B-ADRENERGIC BLOCKER
    Roberto Groszmann; Fiscal Year: 1993
    ..time beta- blocker therapy is initiated, since in these studies patients already have varices and frequently have ascites. Experimental studies have shown that propranolol therapy, administered in the early stages of portal ..
  7. HER2 LIGAND IN HUMAN BREAST TUMORS
    KERMIT CARRAWAY; Fiscal Year: 2001
    ..is focused on a novel cell surface glycoprotein complex (sialomucin complex, SMC), originally isolated from ascites sublines of the highly metastatic 13762 rat mammary adenocarcinoma...
  8. Effect of Cirrhosis and Shunts on Drug Disposition
    Stephen Hall; Fiscal Year: 2006
    ..major complications of cirrhosis such as bleeding from gastroesophageal varices, hepatic encephalopathy, and ascites. Transjugular intrahepatic portosystemic shunts (TIPS) and other surgical shunts are performed to manage these ..
  9. Effect of Cirrhosis and Shunts on Drug Disposition
    J Gorski; Fiscal Year: 2005
    ..major complications of cirrhosis such as bleeding from gastroesophageal varices, hepatic encephalopathy, and ascites. Transjugular intrahepatic portosystemic shunts (TIPS) and other surgical shunts are performed to manage these ..
  10. Synergistic actions by multiple Toll-like receptors in alcoholic liver disease
    Ekihiro Seki; Fiscal Year: 2010
    ..Not only LPS, but also bacterial DNA levels in blood and ascites are elevated in patients with alcoholic-induced liver cirrhosis...
  11. OCULAR SURFACE PROTECTION BY SIALOMUCIN COMPLEX
    KERMIT CARRAWAY; Fiscal Year: 2002
    ..SMC was originally identified and isolated from membranes of ascites sublines of the highly metastatic 13762 rat mammary adenocarcinoma and is composed of a mucin subunit ASGP-1 (..
  12. Novel, cost-effective production of immunoaffinity Abs
    Scott Franklin; Fiscal Year: 2006
    ..including culture of hybridomas, re-introduction of hybridomas into mice and subsequent generation of ascites and transfection of mammalian cell lines with specific heavy and light chain antibody genes...
  13. TRIPTYCENE ANALOGS--NOVEL BIFUNCTIONAL ANTICANCER DRUGS
    Jean Pierre Perchellet; Fiscal Year: 2004
    ..TT2 derivatives can inhibit tumor development in vivo and prolong the survival of mice challenged with ascites (L1210) or solid tumors with metastatic potential (Lewis lung carcinoma and B16F10 melanoma)...
  14. Gene Regulation for Drug Targeting in AML
    Manohar Ratnam; Fiscal Year: 2009
    ..The ATRA effect conferred a substantial therapeutic benefit, on FR-targeted liposomal doxorubicin, in a mouse ascites tumor model of AML...