pathologic dilatation

..To report on the management of laryngoceles by CO2 laser-assisted endoscopic excision...

..An infected laryngocele is called a laryngopyocele. Our experience with a case of laryngopyocele with signs on computed tomography before and after antibiotic therapy is presented since laryngopyocele is more unusual...

..We reviewed our institutional experience with Dacron (DuPont, Wilmington, DE) mesh wrap support of dilated ascending aortas...

..Absence of a significant correlation between the dimensions of the ectatic segments and IL-6 levels might be due to the narrower range of the diameters of the coronary arteries compared with the abdominal aorta...

..The children with BAV had significantly larger aortic roots (p <0.001) regardless of the presence of aortic stenosis or regurgitation...

..Dilatation and tortuosity of extramural coronary arteries are prevalent in cyanotic congenital heart disease. Two pathogenetic variables are operative, namely endothelial vasodilator substances and medial structural abnormalities...

..The present study examines the incidence of coronary artery ectasia in patients with aneurysms of the ascending aorta...

..Ascending aortic diameter and the extension of aortic dilation were significantly correlated with age, but no correlation was found between aortic dimensions and aortic valve morphology...

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..Histopathologic lesions in all birds consisted of multifocal lymphoplasmacytic infiltration of myenteric and cardiac nerves and ganglia. These lesions are characteristic of proventricular dilatation disease of psittacine birds...

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..To investigate the relation between aortic elastic properties and size in bicuspid aortic valves (BAVs)...

..The purpose of the article is to draw conclusions on the applicability of reduction ascending aortoplasty in modern cardiovascular surgery...

..While gastric bypass is highly successful in the majority of patients, significant weight regain can occur over time due to stretching of the gastric pouch and stoma...

..The present study examined temporal and spatial patterns of extracellular matrix and smooth muscle cell changes in the ascending aorta with bicuspid and tricuspid aortic valve stenosis...

..CAE was associated with obstructive coronary artery disease in more than 80% of cases. The RCA was most commonly affected and most patients had single vessel involvement...

..The prevalence of CAA among cocaine users was higher than expected (30.4%), given such a young cohort. Cocaine use may predispose to the formation of CAA, which may in turn be a contributing factor to myocardial infarction...

..Our aim was to compare TFC with magnetic resonance peak flow velocity (PFV) for the evaluation of the coronary flow in patients with CAE...

..This study aimed to describe the features and identify the predictors of ascending aorta dilatation in patients with congenital bicuspid aortic valve (BAV)...

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..Complications of bariatric surgery include stomal stenosis and/or ulcer and stomal dilation (secondary to overeating). The latter complication can result in a gain of previously lost weight...

..This study sought to assess elasticity and dimensions of the aorta and their impact on aortic valve competence and left ventricular (LV) function in patients with a nonstenotic bicuspid aortic valve (BAV)...

..43, P = .001). CONCLUSIONS: Aortic root dilatation is associated with higher MMP release, which may indicate the role of increased collagenolytic and elastolytic activities in hypertension-induced aortic root dilatation...

..To describe the incidence and rate of dilatation of the ascending aorta in children with bicuspid aortic valve (BAV) and to determine factors that predict rapid aortic dilatation...

..However, the relation between carotid IMT and isolated coronary artery ectasia (CAE) has not been investigated. The aim of our study was to assess this relation...

..In the present study, we assessed carotid intima-media thickness and common carotid artery diameter in patients with and without coronary artery ectasia...

..The presence of a bicuspid aortic valve (BAV) might be associated with a progressive dilatation of the aortic root and ascending aorta. However, involvement of the aortic arch and descending aorta has not yet been elucidated...

..Both coronary artery dilatation and supravalvular pulmonary stenosis, although rarely reported, are abnormalities of the cardiovascular system that may occur in Noonan syndrome...

..Further studies could clarify the relations between these findings and the pathogenesis of aortic dilatation in bicuspid aortic valve patients...

..Recently increased prevalence of peripheral varicose veins has been shown in patients with CAE. In this study we aimed to assess the prevalence of varicocele, which is dilatation of another venous system, in patients with CAE...

..This study investigates the mechanics and histology of healthy and dilated human ascending aortas (AA). The regional variation in mechanical response and tissue structure were compared...

..Dural ectasia has been classified as a major diagnostic criterion; however, its prevalence is not known. We aimed to identify the true prevalence of dural ectasia in Marfan's syndrome, and to investigate its relation to aortic pathology...

..3-5.3% of angiographic studies. Our objective was to evaluate the prevalence of this condition, to analyze its clinical and angiographic characteristics, and to compare patients with ectasia and patients without it...

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..The BSA predicted aortic size at all positions. The prevalence of aortic dilation and aneurysm was lower in this population of girls and younger women with TS than in older TS populations...

..Patients with bicuspid aortic valve are at increased risk for aortic complications...

..CONCLUSIONS: In a community-based study, BAV is associated with an alteration of aortic dimensions even in the absence of hemodynamically significant aortic valve stenosis or regurgitation...

..Thus, we investigated the role of matrix metalloproteinases (MMP), tissue inhibitor of matrix metalloproteinases (TIMP-1), and inflammatory markers [high-sensitive C-reactive protein, interleukins (ILs)] in CAE patients...

..The purpose of this study was to investigate coronary blood flow properties in patients with diffuse coronary artery ectasia (CAE) associated with exercise-induced myocardial ischemia...

..CONCLUSIONS: Both the flap and the stromal bed of the cornea may thin after LASIK. A residual stromal bed thickness of 250 microm does not preclude the development of keratectasia after LASIK...

..Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds...

..To evaluate the dimensions of the aortic root in a selected population of young males with isolated normally functioning bicuspid aortic valve...

..Some patients are thought to regain weight after gastric bypass surgery because of dilation of the gastrojejunal anastomosis (GJA) and/or gastric pouch...

..To evaluate keratectasia after laser in situ keratomileusis (LASIK) for high myopia...

..CONCLUSION: Despite the limitations of the small sample size, the study's results suggest that parameters besides residual corneal bed thickness (eg, age, attempted correction) may have to be considered to avoid post-LASIK ectasia...

..Although dilated coronary arteries are uncommon in children, three cases are presented which, even more unusually, were not associated with Kawasaki's disease..

..For almost 40 years, a viral etiology for PDD has been suspected, but to date no candidate etiologic agent has been reproducibly linked to the disease...

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..Correlations between arterial and venous ectasias have not been established. We sought to examine whether there is an association between CAE and VV...

..Diabetes mellitus was found to be independently but inversely associated with CAE (relative risk 0.603, 95% confidence interval 0.375 to 0.960, p = 0.037), thus resembling the relation between diabetes and AAA...

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..TIMI frame counts can be regarded as an index of the severity of impaired coronary flow in patients with coronary artery ectasia...

..This process of vascular matrix remodeling in patients with bicuspid aortic valves offers novel therapeutic targets to prevent the aortic degeneration and dilatation characteristic of this disease...

..CONCLUSIONS: AVR could not prevent progressive aortic dilation in BAV. Since the aorta did not dilate in TAV, progressive aortic dilation in BAV seems mainly due to the fragility of the aortic wall rather than hemodynamic factors...

..A retrospective diagnosis of ectatic corneal disorder was made in a patient who had no obvious findings of corneal pathology prior to LASIK...

..These observations suggest that the MMP-TIMP system appears to play a significant role in the development of coronary ectasia..

..To the best of our knowledge this is believed to be the first description of a santorinicele associated with these characteristic findings...

..To analyze the visual outcomes and method of final visual correction in eyes with corneal ectasia after laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK)...

..The shape of the applanation signal yielded important information in addition to corneal hysteresis and corneal resistance factor...

..To describe 2 cases of post-laser in situ keratomileusis (LASIK) ectasia managed with deep anterior lamellar keratoplasty (DALK)...

..This pattern was detected retrospectively in 2 patients who developed post-LASIK ectasia and prospectively in 4 patients who had other corneal abnormalities suggestive of keratoconus...

..To report two cases of corneal ectasia, which developed after hyperopic LASIK...

..To report a case of ectasia occurring > 4 years following LASIK with no risk factors and a residual stromal bed > 300 microm...

..Preoperative corneal pachymetry, topography, and attempted correction were similar in both eyes. In patients whose corneas may be predisposed to instability, PRK may be a safer alternative procedure than LASIK...

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..To report a case of severe bilateral ectasia after LASIK that was treated with implantation of small-diameter Keraring intrastromal corneal ring segments (Mediphacos Ltd)...

..To examine a database of laser in situ keratomileusis (LASIK) procedures for preoperative and operative factors assumed to increase the risk for developing post-LASIK ectasia...

..To analyze the epidemiologic features of ectasia after excimer laser corneal refractive surgery, to identify risk factors for its development, and to devise a screening strategy to minimize its occurrence...

..To evaluate changes in posterior corneal elevation using the Pentacam topographer (Oculus) in patients having laser in situ keratomileusis (LASIK) enhancement...

..To improve the visual acuity of patients with progressive keratectasia following laser in situ keratomileusis (LASIK)...

..To our knowledge, this is the first case showing exacerbation of keratectasia despite CCL and, as the exacerbation occurred only during pregnancy, suggesting that hormonal changes might affect corneal biomechanical stability...

..To report three patients (four eyes) with hyperopic keratoconus...

..CONCLUSION: Both Intacs and ILK improved mean UCVA, BCVA, and manifest and topographic astigmatism. In most cases, good contact lens fit was achieved with visual rehabilitation to levels that obviated penetrating keratoplasty...

..05 (SD) (range 0.10 to 0.25 D) before DALK to 0.68 +/- 0.19 D (range 0.5 to 1.0 D) after DALK. Deep anterior lamellar keratoplasty may be a better alternative than penetrating keratoplasty for any pathology with healthy endothelium...

..Corneal ectasia after photorefractive keratectomy (PRK) has only been occasionally reported, and its incidence has not been assessed...

..The patient presented with minimal alterations in manifest refraction but had obvious distortions in the wavefront error of the eye, as demonstrated by InterWave aberrometry...

..To prospectively study the effects of the use of Intacs microthin prescription inserts (Addition Technology Inc, Fremont, Calif) for the postoperative management of corneal ectasia resulting from laser in situ keratomileusis (LASIK)...

..With further study, this technique may prove to be an effective, relatively noninvasive approach...

..To evaluate the forward shift of the posterior corneal surface after myopic laser in situ keratomileusis (LASIK) relative to the residual stromal bed thickness and the ablation percentage of the total corneal thickness...

..To evaluate the potential of using intrastromal corneal ring technology (Intacs, KeraVision) to correct posterior ectasia after laser in situ keratomileusis (LASIK) for myopia...

..Corneal topography data along with regional corneal pachymetry must be interpreted carefully to detect these cases. Laser in situ keratomileusis can lead to a rapid progression of PMCD...

..Multiple enhancements were common among affected cases, but their causative role remains unknown. We did not identify any patients who developed ectasia without recognizable preoperative risk factors...

..001) was also lower in group 1. CONCLUSIONS: Posterior corneal elevation increases after repeat LASIK. Eyes with an increase in posterior corneal elevation after primary LASIK and with thinner cornea are more predisposed...

..Eyes with thin corneas and high myopia requiring greater laser ablation are more predisposed to an anterior shift of the cornea...

..CONCLUSION: Proper contact lens fitting based on topographic data and slitlamp evaluation allowed good visual rehabilitation and comfortable extended daily wear in patients with keratectasia after LASIK...

..Until we have a better understanding of corneal strength, we think surface photorefractive keratectomy or laser-assisted subepithelial keratectomy ablations should be considered instead of LASIK in borderline cases...

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..Translation to the treatment of painful bladder syndromes like 1C would be highly probable. ..

..Translation to the treatment of IC would be highly probable. ..

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..Translation to the treatment of painful bladder syndromes like 1C would be highly probable. ..

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..OAT-NUC is the only viability ancillary study of OAT, and thus serves a critical need in assessing potential mechanisms of the findings in OAT. ..

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..The findings should improve understanding of surgical weight loss in morbidly obese patients and have clinical applications in the postoperative care of such patients. ..

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..Preliminary evidence supports the feasibility of the work and suggests that the results could lead to a number of new targets for improvements in pain therapy. ..

..The findings may also improve our understanding of the causes of obesity, which could lead to new less invasive treatments. ..

..Ultimately, this work may improve our ability to treat KC and/or prevent the development of KC. ..

..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..

..We will determine how these proteins are modified by the same processes as found in the diseases states and then test the effects they have on vascular ion channels and blood vessel function. ..

..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..

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..The results of these experiments will provide new insights into the mechanism and function of the myogenic response at the network, single vessel, and cellular levels...

..The work should have relevance to the field of pain mechanisms. ..

..It is hoped that the results of these studies will be useful for a better understanding of pain mechanisms and of pain therapy in humans...

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..The results will be essential in identifying potential mechanisms by which CR acts in cancer prevention and delay of the aging process in long-lived species such as the rhesus monkey and humans. ..

..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..

..This study will investigate how inflammation caused by the heart-lung machine selectively damages cerebral white matter which plays a key role in the development of motor skills. ..

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..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..

..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..

..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..

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..It also will demonstrate the utility of near infrared spectroscopy as a clinical method for avoid brain injury during pediatric cardiac surgery. ..

..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..