pathologic dilatation

Summary

Summary: The condition of an anatomical structure's being dilated beyond normal dimensions.

Top Publications

  1. pmc Aortic root dilatation in young men with normally functioning bicuspid aortic valves
    S Nistri
    Sanitary Service, Regione Carabinieri Veneto, Via Brigata Padova 19, 35100 Padova, Italy
    Heart 82:19-22. 1999
  2. ncbi Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation
    Paul W M Fedak
    Division of Cardiac Surgery, University of Toronto and Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
    J Thorac Cardiovasc Surg 126:797-806. 2003
  3. ncbi Corneal ectasia induced by laser in situ keratomileusis
    I G Pallikaris
    Department of Ophthalmology, Vardinoyannion Eye Institute of Crete, University of Crete, Heraklio, Greece
    J Cataract Refract Surg 27:1796-802. 2001
  4. pmc Dilatation of the ascending aorta in paediatric patients with bicuspid aortic valve: frequency, rate of progression and risk factors
    A E Warren
    Division of Pediatric Cardiology, Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    Heart 92:1496-500. 2006
  5. pmc Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent
    Amy L Kistler
    Departments of Biochemistry, Microbiology and Medicine, Howard Hughes Medical Institute, University of California, San Francisco, 94143, USA
    Virol J 5:88. 2008
  6. doi Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: focus on cell-matrix signaling
    Alessandro Della Corte
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, V Monaldi Hospital, Naples, Italy
    J Thorac Cardiovasc Surg 135:8-18, 18.e1-2. 2008
  7. ncbi Dilatation of the aorta in pure, severe, bicuspid aortic valve stenosis
    Gareth J Morgan-Hughes
    Department of Cardiology, South West Cardiothoracic Centre, Plymouth NHS Trust, Plymouth, United Kingdom
    Am Heart J 147:736-40. 2004
  8. ncbi Different patterns of extracellular matrix protein expression in the convexity and the concavity of the dilated aorta with bicuspid aortic valve: preliminary results
    Maurizio Cotrufo
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, Italy
    J Thorac Cardiovasc Surg 130:504-11. 2005
  9. ncbi Right ventricular dilatation during exercise. A new sign?
    Carlos Cotrim
    Serviço de Cardiologia do Hospital Garcia de Orta, Almada, Portugal
    Rev Port Cardiol 26:939-40. 2007
  10. ncbi Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis
    Bryce A Binstadt
    Rheumatology Program, Division of Immunology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 116:e89-93. 2005

Detail Information

Publications205 found, 100 shown here

  1. pmc Aortic root dilatation in young men with normally functioning bicuspid aortic valves
    S Nistri
    Sanitary Service, Regione Carabinieri Veneto, Via Brigata Padova 19, 35100 Padova, Italy
    Heart 82:19-22. 1999
    ..To evaluate the dimensions of the aortic root in a selected population of young males with isolated normally functioning bicuspid aortic valve...
  2. ncbi Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation
    Paul W M Fedak
    Division of Cardiac Surgery, University of Toronto and Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
    J Thorac Cardiovasc Surg 126:797-806. 2003
    ..In bicuspid aortic valve disease a deficiency of fibrillin-1 and increased matrix metalloproteinase matrix degradation might result in aortic degeneration and dilatation...
  3. ncbi Corneal ectasia induced by laser in situ keratomileusis
    I G Pallikaris
    Department of Ophthalmology, Vardinoyannion Eye Institute of Crete, University of Crete, Heraklio, Greece
    J Cataract Refract Surg 27:1796-802. 2001
    ..CONCLUSION: Despite the limitations of the small sample size, the study's results suggest that parameters besides residual corneal bed thickness (eg, age, attempted correction) may have to be considered to avoid post-LASIK ectasia...
  4. pmc Dilatation of the ascending aorta in paediatric patients with bicuspid aortic valve: frequency, rate of progression and risk factors
    A E Warren
    Division of Pediatric Cardiology, Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    Heart 92:1496-500. 2006
    ..To describe the incidence and rate of dilatation of the ascending aorta in children with bicuspid aortic valve (BAV) and to determine factors that predict rapid aortic dilatation...
  5. pmc Recovery of divergent avian bornaviruses from cases of proventricular dilatation disease: identification of a candidate etiologic agent
    Amy L Kistler
    Departments of Biochemistry, Microbiology and Medicine, Howard Hughes Medical Institute, University of California, San Francisco, 94143, USA
    Virol J 5:88. 2008
    ..For almost 40 years, a viral etiology for PDD has been suspected, but to date no candidate etiologic agent has been reproducibly linked to the disease...
  6. doi Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: focus on cell-matrix signaling
    Alessandro Della Corte
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, V Monaldi Hospital, Naples, Italy
    J Thorac Cardiovasc Surg 135:8-18, 18.e1-2. 2008
    ..The present study examined temporal and spatial patterns of extracellular matrix and smooth muscle cell changes in the ascending aorta with bicuspid and tricuspid aortic valve stenosis...
  7. ncbi Dilatation of the aorta in pure, severe, bicuspid aortic valve stenosis
    Gareth J Morgan-Hughes
    Department of Cardiology, South West Cardiothoracic Centre, Plymouth NHS Trust, Plymouth, United Kingdom
    Am Heart J 147:736-40. 2004
    ....
  8. ncbi Different patterns of extracellular matrix protein expression in the convexity and the concavity of the dilated aorta with bicuspid aortic valve: preliminary results
    Maurizio Cotrufo
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, Italy
    J Thorac Cardiovasc Surg 130:504-11. 2005
    ..This study aimed to assess extracellular matrix protein expression patterns at the convexity (right anterolateral wall) and the concavity of the dilated ascending aorta in patients with bicuspid aortic valve disease...
  9. ncbi Right ventricular dilatation during exercise. A new sign?
    Carlos Cotrim
    Serviço de Cardiologia do Hospital Garcia de Orta, Almada, Portugal
    Rev Port Cardiol 26:939-40. 2007
  10. ncbi Coronary artery dilation among patients presenting with systemic-onset juvenile idiopathic arthritis
    Bryce A Binstadt
    Rheumatology Program, Division of Immunology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    Pediatrics 116:e89-93. 2005
    ..To evaluate coronary artery diameters among patients presenting with systemic-onset juvenile idiopathic arthritis (SoJIA)...
  11. ncbi Bilateral keratectasia after unilateral laser in situ keratomileusis: a retrospective diagnosis of ectatic corneal disorder
    Jim C Wang
    Kaiser Permanente Medical Center, Department of Ophthalmology, Fontana, California 92335, USA
    J Cataract Refract Surg 29:2015-8. 2003
    ..A retrospective diagnosis of ectatic corneal disorder was made in a patient who had no obvious findings of corneal pathology prior to LASIK...
  12. ncbi Aortic dimensions in patients with bicuspid aortic valve without significant valve dysfunction
    Moreno Cecconi
    Ospedale Cardiologico G M Lancisi, Via Guazzatore 66, 60027 Osimo, Ancona, Italy
    Am J Cardiol 95:292-4. 2005
    ..Ascending aortic diameter and the extension of aortic dilation were significantly correlated with age, but no correlation was found between aortic dimensions and aortic valve morphology...
  13. ncbi Extramural coronary arteries in adults with cyanotic congenital heart disease
    Reema Chugh
    Ahmanson UCLA Adult Congenital Heart Disease Center, Department of Pathology and Laboratory Medicine, UCLA School of Medicine, Los Angeles, California 90095 1679, USA
    Am J Cardiol 94:1355-7. 2004
    ..Dilatation and tortuosity of extramural coronary arteries are prevalent in cyanotic congenital heart disease. Two pathogenetic variables are operative, namely endothelial vasodilator substances and medial structural abnormalities...
  14. ncbi Keratectasia after laser in situ keratomileusis (LASIK): evaluation of the calculated residual stromal bed thickness
    Richard J Ou
    Jules Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Am J Ophthalmol 134:771-3. 2002
    ..To report corneal histopathology associated with keratectasia after laser in situ keratomileusis (LASIK) and to evaluate the thickness of the calculated residual stromal bed in two cases and those in the literature...
  15. ncbi Latrogenic keratectasia following laser in situ keratomileusis
    Leopoldo Spadea
    University of L Aquila, Italy
    J Refract Surg 18:475-80. 2002
    ..To evaluate keratectasia after laser in situ keratomileusis (LASIK) for high myopia...
  16. ncbi Local mechanical and structural properties of healthy and diseased human ascending aorta tissue
    Nusrat Choudhury
    Department of Chemical Engineering, McGill University, Montreal, Quebec, Canada
    Cardiovasc Pathol 18:83-91. 2009
    ..This study investigates the mechanics and histology of healthy and dilated human ascending aortas (AA). The regional variation in mechanical response and tissue structure were compared...
  17. ncbi The Tailor of Gloucester: a jacket for the Marfan's aorta
    Tal Golesworthy
    Lancet 364:1582. 2004
  18. ncbi Is aortic wall degeneration related to bicuspid aortic valve anatomy in patients with valvular disease?
    Claudio F Russo
    Angelo De Gasperis Department of Cardiac Surgery, Niguarda Ca Granda Hospital, Piazza Ospedale Maggiore, Milan, Italy
    J Thorac Cardiovasc Surg 136:937-42. 2008
    ..Patients with bicuspid aortic valve are at increased risk for aortic complications...
  19. ncbi Peroral endoscopic reduction of dilated gastrojejunal anastomosis after Roux-en-Y gastric bypass: a possible new option for patients with weight regain
    C C Thompson
    Department of Medicine, Gastroenterology Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    Surg Endosc 20:1744-8. 2006
    ..This study aimed to assess the feasibility of endoscopic gastrojejunal anastomotic tightening and to determine the effect of tightening on body weight...
  20. ncbi Coronary artery ectasias: imaging, functional assessment and clinical implications
    Athanassios Manginas
    First Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece
    Eur Heart J 27:1026-31. 2006
    ..The prognosis of coronary ectasias is controversial and prospective studies focusing on conservative or invasive strategies to prevent cardiac complications are needed...
  21. ncbi Endoscopic CO2 laser management of laryngocele
    Pablo Martinez Devesa
    Professorial Unit of the Royal National Throat, Nose and Ear Hospital, London, United Kingdom
    Laryngoscope 112:1426-30. 2002
    ..To report on the management of laryngoceles by CO2 laser-assisted endoscopic excision...
  22. ncbi Laryngopyocele: signs on computed tomography
    H Nazaroglu
    Dicle Universitesi Tip Fakültesi Radyoloji Anabilim Dali, Diyarbakir, Turkey
    Eur J Radiol 33:63-5. 2000
    ..An infected laryngocele is called a laryngopyocele. Our experience with a case of laryngopyocele with signs on computed tomography before and after antibiotic therapy is presented since laryngopyocele is more unusual...
  23. ncbi Clinical course of patients with coronary ectasia
    K Takahashi
    First Department of Internal Medicine, Hyogo College of Medicine, Hyogo, Japan
    Cardiology 91:145-9. 1999
    ..To compare the clinical prognosis between patients with diffuse coronary ectasia and those with localized coronary ectasia...
  24. ncbi Size reduction ascending aortoplasty: is it dead or alive?
    Francis Robicsek
    Department of Thoracic and Cardiovascular Surgery and Heineman Medical Research Laboratories at Carolinas Medical Center, Charlotte, NC, USA
    J Thorac Cardiovasc Surg 128:562-70. 2004
    ..The purpose of the article is to draw conclusions on the applicability of reduction ascending aortoplasty in modern cardiovascular surgery...
  25. ncbi Frequency of coronary artery ectasia in patients undergoing surgery for ascending aortic aneurysms
    Manolis C Papadakis
    First Cardiology and Second Cardiothoracic Surgery Department, Onassis Cardiac Surgery Center, Athens, Greece
    Am J Cardiol 94:1433-5. 2004
    ..The present study examines the incidence of coronary artery ectasia in patients with aneurysms of the ascending aorta...
  26. ncbi Frequency of aortic root dilation in children with a bicuspid aortic valve
    Michelle Gurvitz
    Division of Cardiology, Department of Pediatrics, Mattel Children s Hospital at UCLA, David Geffen School of Medicine at UCLA, USA
    Am J Cardiol 94:1337-40. 2004
    ..The children with BAV had significantly larger aortic roots (p <0.001) regardless of the presence of aortic stenosis or regurgitation...
  27. ncbi Plasma interleukin-6 levels are increased in coronary artery ectasia
    Lale Tokgozoglu
    Hacettepe University, Department of Cardiology, Ankara, Turkey
    Acta Cardiol 59:515-9. 2004
    ..The aim of this study was to investigate whether a similar association also exists for patients with coronary ectasia, which may also be regarded as an abnormal dilatation of the arterial system...
  28. ncbi Is size-reducing ascending aortoplasty with external reinforcement an option in modern aortic surgery?
    Peter Feindt
    Department of Thoracic and Cardiovascular Surgery, Heinrich Heine University Hospital, Dusseldorf, Germany
    Eur J Cardiothorac Surg 31:614-7. 2007
    ....
  29. ncbi Long-term experience of girdling the ascending aorta with Dacron mesh as definitive treatment for aneurysmal dilation
    Oved Cohen
    Division of Cardiac Surgery, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California90095 1741, USA
    Ann Thorac Surg 83:S780-4; discussion S785-90. 2007
    ..We reviewed our institutional experience with Dacron (DuPont, Wilmington, DE) mesh wrap support of dilated ascending aortas...
  30. ncbi Aortic elasticity and size in bicuspid aortic valve syndrome
    Stefano Nistri
    Cardiology Service CMSR Veneto Medica, Via Vicenza, 204, Altavilla Vicentina VI, 36077 Vicenza, Italy
    Eur Heart J 29:472-9. 2008
    ..To investigate the relation between aortic elastic properties and size in bicuspid aortic valves (BAVs)...
  31. ncbi Plasma soluble adhesion molecules; intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin levels in patients with isolated coronary artery ectasia
    Hasan Turhan
    Inonu University Medical Faculty, Department of Cardiology, Malatya, Turkey
    Coron Artery Dis 16:45-50. 2005
    ..001; E-selectin, 74 +/- 21 versus 49 +/- 9, respectively, P < 0.001), suggesting the presence of a more severe and extensive chronic inflammation in the coronary circulation in patients with isolated CAE...
  32. ncbi Expression of monocyte and lymphocyte adhesion molecules is increased in isolated coronary artery ectasia
    Nesligul Yildirim
    Departments of Cardiology, Faculty of Medicine, Zonguldak Karaelmas University, Kozlu Zonguldak, Turkey
    Coron Artery Dis 18:49-53. 2007
    ....
  33. ncbi Weight gain after bariatric surgery as a result of a large gastric stoma: endotherapy with sodium morrhuate may prevent the need for surgical revision
    Marc F Catalano
    Department of Medicine, Division of Gastroenterology, St Luke s Medical Center, St Francis Hospital, Milwaukee, Wisconsin 53219, USA
    Gastrointest Endosc 66:240-5. 2007
    ..Complications of bariatric surgery include stomal stenosis and/or ulcer and stomal dilation (secondary to overeating). The latter complication can result in a gain of previously lost weight...
  34. ncbi Reduced aortic elasticity and dilatation are associated with aortic regurgitation and left ventricular hypertrophy in nonstenotic bicuspid aortic valve patients
    Heynric B Grotenhuis
    Department of Radiology, Center for Congenital Anomalies of the Heart, Leiden, The Netherlands
    J Am Coll Cardiol 49:1660-5. 2007
    ..This study sought to assess elasticity and dimensions of the aorta and their impact on aortic valve competence and left ventricular (LV) function in patients with a nonstenotic bicuspid aortic valve (BAV)...
  35. ncbi Relationship between circulating plasma matrix metalloproteinase-9 (gelatinase-B) concentration and aortic root dilatation
    Osman Karakaya
    Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, Turkey
    Am J Hypertens 19:361-5. 2006
    ..However, its role in the development of aortic root dilatation has not been studied. We therefore attempted to determine the relationship between aortic root diameter and MMP-9 concentration in a hypertensive population...
  36. ncbi Bilateral coronary artery dilatation and supravalvular pulmonary stenosis in a child with noonan syndrome
    T Ucar
    Department of Pediatric Cardiology, Ankara University School of Medicine, Ankara, Turkey
    Pediatr Cardiol 26:848-50. 2005
    ..Both coronary artery dilatation and supravalvular pulmonary stenosis, although rarely reported, are abnormalities of the cardiovascular system that may occur in Noonan syndrome...
  37. ncbi Increased prevalence of varicocele in patients with coronary artery ectasia
    Ertan Yetkin
    Department of Cardiology, Inonu University School of Medicine, Malatya, and Diyarbakir Government Hospital, Department of Urology, Diyarbakir, Turkey
    Coron Artery Dis 16:261-4. 2005
    ..Recently increased prevalence of peripheral varicose veins has been shown in patients with CAE. In this study we aimed to assess the prevalence of varicocele, which is dilatation of another venous system, in patients with CAE...
  38. ncbi Coronary flow evaluation by TIMI frame count and magnetic resonance flow velocity in patients with coronary artery ectasia
    Sophie I Mavrogeni
    Onassis Cardiac Surgery Center, Athens, Greece
    J Cardiovasc Magn Reson 7:545-50. 2005
    ..Our aim was to compare TFC with magnetic resonance peak flow velocity (PFV) for the evaluation of the coronary flow in patients with CAE...
  39. ncbi Natural history of a dilated ascending aorta after aortic valve replacement
    Katsuhiko Matsuyama
    Nagoya University Graduate School of Medicine, Department of Cardio Thoracic Surgery, Nagoya, Japan
    Circ J 69:392-6. 2005
    ....
  40. ncbi Weight gain after bariatric surgery as a result of large gastric stoma: endotherapy with sodium morrhuate to induce stomal stenosis may prevent the need for surgical revision
    John M Morton
    Gastrointest Endosc 66:246-7. 2007
  41. ncbi Dilatation of the entire thoracic aorta in patients with bicuspid aortic valve: a magnetic resonance angiography study
    M Westhoff-Bleck
    Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany
    Vasa 34:181-5. 2005
    ..The presence of a bicuspid aortic valve (BAV) might be associated with a progressive dilatation of the aortic root and ascending aorta. However, involvement of the aortic arch and descending aorta has not yet been elucidated...
  42. ncbi Predictors of ascending aortic dilatation with bicuspid aortic valve: a wide spectrum of disease expression
    Alessandro Della Corte
    Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, V Monaldi Hospital, Via L Bianchi, 80131 Naples, Italy
    Eur J Cardiothorac Surg 31:397-404; discussion 404-5. 2007
    ..This study aimed to describe the features and identify the predictors of ascending aorta dilatation in patients with congenital bicuspid aortic valve (BAV)...
  43. ncbi Endoscopic intraluminal suture plication of the gastric pouch and stoma in postoperative Roux-en-Y gastric bypass patients
    Michael Schweitzer
    The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Laparoendosc Adv Surg Tech A 14:223-6. 2004
    ..While gastric bypass is highly successful in the majority of patients, significant weight regain can occur over time due to stretching of the gastric pouch and stoma...
  44. ncbi Increased thrombolysis in myocardial infarction frame counts in patients with isolated coronary artery ectasia
    Kubilay Senen
    Department of Cardiology, TYIH, Ankara, Turkey
    Heart Vessels 19:23-6. 2004
    ..TIMI frame counts can be regarded as an index of the severity of impaired coronary flow in patients with coronary artery ectasia...
  45. ncbi Failure to prevent progressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valve
    Hisayo Yasuda
    Department of Cardiology, National Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka 565 8565, Japan
    Circulation 108:II291-4. 2003
    ..Patients with bicuspid aortic valve (BAV) have been frequently complicated with ascending aortic dilation possibly because of hemodynamic burdens by aortic stenosis (AS) or regurgitation (AR) or congenital fragility of the aortic wall...
  46. ncbi Ectopic opening of the common bile duct in the duodenal bulb: clinical implications
    Sang Soo Lee
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Gastrointest Endosc 57:679-82. 2003
    ..This study analyzed the clinical implications and cholangiographic findings of this anomaly...
  47. doi Matrix metalloproteinases and inflammatory markers in coronary artery ectasia: their relationship to severity of coronary artery ectasia
    Abdullah Dogan
    Department of Cardiology, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    Coron Artery Dis 19:559-63. 2008
    ..Thus, we investigated the role of matrix metalloproteinases (MMP), tissue inhibitor of matrix metalloproteinases (TIMP-1), and inflammatory markers [high-sensitive C-reactive protein, interleukins (ILs)] in CAE patients...
  48. pmc Novel borna virus in psittacine birds with proventricular dilatation disease
    Kirsi S Honkavuori
    Columbia University, New York, NY, USA
    Emerg Infect Dis 14:1883-6. 2008
    ..Real-time PCR confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds...
  49. doi Turner syndrome is an independent risk factor for aortic dilation in the young
    Leo Lopez
    Children s Hospital at Montefiore, Division of Pediatric Cardiology, 3415 Bainbridge Ave, Rosenthal 3, Bronx, NY 10467, USA
    Pediatrics 121:e1622-7. 2008
    ....
  50. ncbi Altered coronary flow properties in diffuse coronary artery ectasia
    Omer Akyurek
    Department of Cardiology, Ankara University Medical School, Ankara, Turkey
    Am Heart J 145:66-72. 2003
    ..The purpose of this study was to investigate coronary blood flow properties in patients with diffuse coronary artery ectasia (CAE) associated with exercise-induced myocardial ischemia...
  51. ncbi Bicuspid aortic valve associated with aortic dilatation: a community-based study
    Vuyisile T Nkomo
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    Arterioscler Thromb Vasc Biol 23:351-6. 2003
    ..An independent association of BAV and aortic dilatation in a community-based study has not been demonstrated...
  52. ncbi Treatment of weight regain after gastric bypass surgery when using a new endoscopic platform: initial experience and early outcomes (with video)
    Daniel K Mullady
    Division of Gastroenterology, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Gastrointest Endosc 70:440-4. 2009
    ..Some patients are thought to regain weight after gastric bypass surgery because of dilation of the gastrojejunal anastomosis (GJA) and/or gastric pouch...
  53. ncbi Importance of dural ectasia in phenotypic assessment of Marfan's syndrome
    R Fattori
    Institute of Radiology, University Hospital S Orsola, Bologna, Italy
    Lancet 354:910-3. 1999
    ..Dural ectasia has been classified as a major diagnostic criterion; however, its prevalence is not known. We aimed to identify the true prevalence of dural ectasia in Marfan's syndrome, and to investigate its relation to aortic pathology...
  54. doi Aortic dimensions in girls and young women with turner syndrome: a magnetic resonance imaging study
    Line Cleemann
    Department of Paediatrics, Hillerød Hospital, 3400 Hillerød, Denmark
    Pediatr Cardiol 31:497-504. 2010
    ..The BSA predicted aortic size at all positions. The prevalence of aortic dilation and aneurysm was lower in this population of girls and younger women with TS than in older TS populations...
  55. ncbi Coronary ectasia in familial hypercholesterolemia: histopathologic study regarding matrix metalloproteinases
    K Kajinami
    Second Department of Internal Medicine, School of Medicine, Kanazawa University, Japan
    Mod Pathol 12:1174-80. 1999
    ..These observations suggest that the MMP-TIMP system appears to play a significant role in the development of coronary ectasia..
  56. ncbi [Coronary ectasia: prevalence, and clinical and angiographic characteristics]
    Eduardo Pinar Bermúdez
    Servicio de Cardiología Hospital Universitario Virgen de la Arrixaca Murcia España
    Rev Esp Cardiol 56:473-9. 2003
    ..3-5.3% of angiographic studies. Our objective was to evaluate the prevalence of this condition, to analyze its clinical and angiographic characteristics, and to compare patients with ectasia and patients without it...
  57. ncbi Pancreas divisum and "santorinicele": diagnosis with dynamic MR cholangiopancreatography with secretin stimulation
    R Manfredi
    Department of Radiology, A Gemelli University Hospital, 8 Largo A Gemelli, Rome, Italy
    Radiology 217:403-8. 2000
    ..To evaluate the usefulness of magnetic resonance (MR) cholangiopancreatography (MRCP) before and after secretin administration in diagnosing santorinicele in patients with pancreas divisum...
  58. ncbi Decreased carotid intima-media thickness in patients with coronary artery ectasia compared with patients with coronary artery disease
    Ertan Yetkin
    Department of Cardiology, Inonu University School of Medicine, Malatya, Turkey
    Coron Artery Dis 16:495-8. 2005
    ..In the present study, we assessed carotid intima-media thickness and common carotid artery diameter in patients with and without coronary artery ectasia...
  59. ncbi Carotid intima-media thickness in patients with isolated coronary artery ectasia
    Sukru Celik
    KTU Faculty of Medicine, Department of Cardiology, 61080 Trabzon, Turkey
    Atherosclerosis 190:385-7. 2007
    ..However, the relation between carotid IMT and isolated coronary artery ectasia (CAE) has not been investigated. The aim of our study was to assess this relation...
  60. ncbi Decreased nitrate-mediated dilatation in patients with coronary artery ectasia: an ultrasonographic evaluation of brachial artery
    Yuksel Aksoy
    Department of Cardiology, Inonu University School of Medicine, Malatya, Turkey
    Coron Artery Dis 17:365-9. 2006
    ..In the present study, we aimed to compare flow-mediated and nitrate-mediated responses of brachial artery in patients with coronary artery ectasia and patients with coronary artery disease...
  61. ncbi Increased prevalence of coronary artery aneurysms among cocaine users
    Aaron Satran
    Department of Internal Medicine and Division of Cardiology, Hennepin County Medical Center, Minneapolis, USA
    Circulation 111:2424-9. 2005
    ..After observing CAAs in multiple young cocaine users, we investigated the prevalence of CAAs among cocaine users undergoing coronary angiography...
  62. ncbi High lipoprotein(a) levels and small apolipoprotein(a) sizes are associated with endothelial dysfunction in a multiethnic cohort
    Henry D Wu
    Department of Medicine, Columbia University, New York, New York 10032, USA
    J Am Coll Cardiol 43:1828-33. 2004
    ..This study sought to determine the effect of lipoprotein(a), or Lp(a), levels and apolipoprotein(a), or apo(a), sizes on endothelial function and to explore ethnic differences in their effects...
  63. ncbi Varicose veins are common in patients with coronary artery ectasia. Just a coincidence or a systemic deficit of the vascular wall?
    A E Androulakis
    Department of State Cardiac, Hippokration Hospital, Athens, Greece
    Eur J Vasc Endovasc Surg 27:519-24. 2004
    ..Correlations between arterial and venous ectasias have not been established. We sought to examine whether there is an association between CAE and VV...
  64. ncbi Lymphoplasmacytic myenteric, subepicardial, and pulmonary ganglioneuritis in four nonpsittacine birds
    David Perpinan
    Maragall Exotics Centre Veterinari, Xiprer 53, 08041 Barcelona, Spain
    J Avian Med Surg 21:210-4. 2007
    ..Histopathologic lesions in all birds consisted of multifocal lymphoplasmacytic infiltration of myenteric and cardiac nerves and ganglia. These lesions are characteristic of proventricular dilatation disease of psittacine birds...
  65. pmc Congenital coronary artery dilatation
    S Chakrabarti
    Southampton University Hospital, Southampton, UK Birmingham Children s Hospital, Birmingham, UK
    Heart 89:595-6. 2003
    ..Although dilated coronary arteries are uncommon in children, three cases are presented which, even more unusually, were not associated with Kawasaki's disease..
  66. ncbi Coronary artery ectasia: a ten-year experience in a tertiary hospital in Singapore
    C S P Lam
    Cardiac Department, The Heart Institute, National University Hospital, 5 Lower Kent Ridge Road, Singapore 119074
    Ann Acad Med Singapore 33:419-22. 2004
    ..To our best knowledge, its incidence has never been described in Singapore. We aimed to determine the incidence of CAE at our teaching hospital and to describe patient and angiographic characteristics...
  67. ncbi Relation of coronary artery ectasia to diabetes mellitus
    Aristides E Androulakis
    State Cardiac Department, Hippokration Hospital, Athens, Greece
    Am J Cardiol 93:1165-7. 2004
    ..Diabetes mellitus was found to be independently but inversely associated with CAE (relative risk 0.603, 95% confidence interval 0.375 to 0.960, p = 0.037), thus resembling the relation between diabetes and AAA...
  68. pmc Avian bornaviruses in psittacine birds from Europe and Australia with proventricular dilatation disease
    Herbert Weissenbock
    University of Veterinary Medicine, Vienna, Austria
    Emerg Infect Dis 15:1453-9. 2009
    ..Viral sequences of 2 birds did not match any of the described sequences and clustered together in a new branch termed ABV-6...
  69. ncbi Santorinicele containing a pancreatic duct stone in a patient with incomplete pancreas divisum
    Kwang Ro Joo
    Department of Internal Medicine, Kyung Hee University Hospital, 1 Hoigi dong, Dongdaemoon gu, Seoul 130 702, Korea
    Yonsei Med J 45:952-5. 2004
    ..To the best of our knowledge this is believed to be the first description of a santorinicele associated with these characteristic findings...
  70. ncbi Deep anterior lamellar keratoplasty for post-LASIK ectasia
    Penny J McAllum
    Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Cornea 26:507-11. 2007
    ..To describe 2 cases of post-laser in situ keratomileusis (LASIK) ectasia managed with deep anterior lamellar keratoplasty (DALK)...
  71. ncbi Correction of severe ectasia after LASIK with intracorneal ring segments
    Antonio Uceda-Montanes
    Vissum Clinica Oftalmologica, Seville, Spain
    J Refract Surg 24:408-11. 2008
    ..To report a case of severe bilateral ectasia after LASIK that was treated with implantation of small-diameter Keraring intrastromal corneal ring segments (Mediphacos Ltd)...
  72. ncbi Corneal ectasia after hyperopic LASIK
    J Bradley Randleman
    Department of Ophthalmology, Emory University and Emory Vision, Atlanta, GA, USA
    J Refract Surg 23:98-102. 2007
    ..To report two cases of corneal ectasia, which developed after hyperopic LASIK...
  73. ncbi Biomechanical characteristics of the ectatic cornea
    Julien Kerautret
    Department of Ophthalmology, Bordeaux Hospital, Bordeaux, France
    J Cataract Refract Surg 34:510-3. 2008
    ..The shape of the applanation signal yielded important information in addition to corneal hysteresis and corneal resistance factor...
  74. doi Ectasia after refractive surgery
    Richard J Duffey
    Ophthalmology 115:1849; autor reply 1849-50. 2008
  75. ncbi Vertical D: a novel topographic pattern in some keratoconus suspects
    Juan Carlos Abad
    Laser Eye Center of Miami, Miami, Florida, USA
    Ophthalmology 114:1020-6. 2007
    ..This pattern was detected retrospectively in 2 patients who developed post-LASIK ectasia and prospectively in 4 patients who had other corneal abnormalities suggestive of keratoconus...
  76. ncbi Ectasia after photorefractive keratectomy
    J Bradley Randleman
    Ophthalmology 114:396; author reply 396-7. 2007
  77. doi Changes in posterior corneal elevation after laser in situ keratomileusis enhancement
    Diego Vicente
    Georgetown University School of Medicine, Washington, District of Columbia, USA
    J Cataract Refract Surg 34:785-8. 2008
    ..To evaluate changes in posterior corneal elevation using the Pentacam topographer (Oculus) in patients having laser in situ keratomileusis (LASIK) enhancement...
  78. ncbi Unilateral corneal ectasia after laser in situ keratomileusis in a patient with uncomplicated photorefractive keratectomy in the fellow eye
    George D Kymionis
    Institute of Vision and Optics, University of Crete, Crete, Greece
    J Cataract Refract Surg 33:859-61. 2007
    ..Preoperative corneal pachymetry, topography, and attempted correction were similar in both eyes. In patients whose corneas may be predisposed to instability, PRK may be a safer alternative procedure than LASIK...
  79. ncbi Intacs implantation with sequential collagen cross-linking treatment in postoperative LASIK ectasia
    Gunhal Kamburoglu
    Kudret Eye Hospital, Kennedy Caddesi No 71, Kavaklidere, Ankara, Turkey 06670
    J Refract Surg 24:S726-9. 2008
    ....
  80. ncbi Risk assessment for ectasia after corneal refractive surgery
    J Bradley Randleman
    Department of Ophthalmology, Emory University, Atlanta, Georgia, USA
    Ophthalmology 115:37-50. 2008
    ..To analyze the epidemiologic features of ectasia after excimer laser corneal refractive surgery, to identify risk factors for its development, and to devise a screening strategy to minimize its occurrence...
  81. ncbi Analysis of ectasia after laser in situ keratomileusis: risk factors
    Perry S Binder
    Private Clinical Practice, San Diego, California 92122, USA
    J Cataract Refract Surg 33:1530-8. 2007
    ..To examine a database of laser in situ keratomileusis (LASIK) procedures for preoperative and operative factors assumed to increase the risk for developing post-LASIK ectasia...
  82. ncbi Delayed ectasia following LASIK with no risk factors: is a 300-microm stromal bed enough?
    Sonal S Tuli
    Department of Ophthalmology, University of Florida, Gainesville, Fla, USA
    J Refract Surg 23:620-2. 2007
    ..To report a case of ectasia occurring > 4 years following LASIK with no risk factors and a residual stromal bed > 300 microm...
  83. ncbi Corneal ectasia after LASIK in one eye and uneventful PRK in the fellow eye
    Mehrdad Mohammadpour
    J Cataract Refract Surg 33:1677; author reply 1677-8. 2007
  84. pmc Visual rehabilitation and outcomes for ectasia after corneal refractive surgery
    Maria A Woodward
    Department of Ophthalmology, Emory University, Atlanta, Georgia, USA
    J Cataract Refract Surg 34:383-8. 2008
    ..To analyze the visual outcomes and method of final visual correction in eyes with corneal ectasia after laser in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK)...
  85. ncbi Pregnancy-related exacerbation of iatrogenic keratectasia despite corneal collagen crosslinking
    Farhad Hafezi
    Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland
    J Cataract Refract Surg 34:1219-21. 2008
    ..To our knowledge, this is the first case showing exacerbation of keratectasia despite CCL and, as the exacerbation occurred only during pregnancy, suggesting that hormonal changes might affect corneal biomechanical stability...
  86. ncbi Post-LASIK ectasia
    A John Kanellopoulos
    Ophthalmology 114:1230. 2007
  87. ncbi Hyperopic keratoconus
    Juan Carlos Abad
    Laser Eye Center of Miami, FL 33145, USA
    J Refract Surg 23:520-3. 2007
    ..To report three patients (four eyes) with hyperopic keratoconus...
  88. pmc New surgical approaches to the management of keratoconus and post-LASIK ectasia
    Bryan U Tan
    Shiley Eye Center, University of California San Diego, La Jolla, California, USA
    Trans Am Ophthalmol Soc 104:212-20. 2006
    ....
  89. ncbi Penetrating keratoplasty for corneal ectasia after laser in situ keratomileusis
    R B Kucumen
    Department of Ophthalmology, Yeditepe University Eye Hospital, Istanbul Turkey
    Eur J Ophthalmol 18:695-702. 2008
    ..To improve the visual acuity of patients with progressive keratectasia following laser in situ keratomileusis (LASIK)...
  90. doi Risk factors for ectasia after LASIK
    Mehrdad Mohammadpour
    J Cataract Refract Surg 34:1056. 2008
  91. ncbi Deep anterior lamellar keratoplasty in post-laser in situ keratomileusis keratectasia
    Alberto Villarrubia
    Instituto de Oftalmología La Arruzafa, Cordoba, Spain
    J Cataract Refract Surg 33:773-8. 2007
    ..05 (SD) (range 0.10 to 0.25 D) before DALK to 0.68 +/- 0.19 D (range 0.5 to 1.0 D) after DALK. Deep anterior lamellar keratoplasty may be a better alternative than penetrating keratoplasty for any pathology with healthy endothelium...
  92. ncbi Intracorneal rings to correct corneal ectasia after laser in situ keratomileusis
    Jorge Alio
    Refractive Surgery and Cornea Unit, Alicante Institute of Ophthalmology, and Miguel Hernández University School of Medicine, Alicante, Spain
    J Cataract Refract Surg 28:1568-74. 2002
    ..To evaluate the potential of using intrastromal corneal ring technology (Intacs, KeraVision) to correct posterior ectasia after laser in situ keratomileusis (LASIK) for myopia...
  93. ncbi Contact lens management of keratectasia after laser in situ keratomileusis for myopia
    Clare O'Donnell
    Department of Optometry and Neuroscience C O, L W, UMIST, PO Box 88, Manchester, M60 1QD, United Kingdom
    Eye Contact Lens 30:144-6. 2004
    ..To present a case in which rigid gas-permeable contact lenses were fit for a patient in whom keratectasia developed after laser in situ keratomileusis (LASIK)...
  94. ncbi Preoperative laser in situ keratomileusis screening: an evolving standard of care
    Richard J Duffey
    J Cataract Refract Surg 30:1822-3. 2004
  95. ncbi Incomplete flap with characteristics similar to corneal ectasia
    Louis D Nichamin
    J Cataract Refract Surg 30:1821-2. 2004
  96. ncbi Incomplete flap with characteristics similar to corneal ectasia
    Jose I Velarde
    J Cataract Refract Surg 30:1819-20; author reply 1820-1. 2004
  97. ncbi Single Intacs segment for post-laser in situ keratomileusis keratectasia
    Russell Pokroy
    Enaim Refractive Surgery Center, Jerusalem, Israel
    J Cataract Refract Surg 30:1685-95. 2004
    ..To describe the visual outcome of implantation of a single Intacs segment (Addition Technology Inc.) in eyes with keratectasia after myopic laser in situ keratomileusis (LASIK)...
  98. ncbi Corneal ectasia after LASIK
    William Jory
    J Refract Surg 20:286. 2004
  99. ncbi Residual bed thickness and corneal forward shift after laser in situ keratomileusis
    Kazunori Miyata
    Miyata Eye Hospital, Miyasaki, Japan
    J Cataract Refract Surg 30:1067-72. 2004
    ..To prospectively assess the forward shift of the cornea after laser in situ keratomileusis (LASIK) in relation to the residual corneal bed thickness...
  100. ncbi Optimization of contact lens fitting in keratectasia patients after laser in situ keratomileusis
    Hyuk Jin Choi
    Department of Ophthalmology, Seoul National University College of Medicine, Korea
    J Cataract Refract Surg 30:1057-66. 2004
    ..To evaluate the clinical outcomes of contact lens fitting in eyes with keratectasia after laser in situ keratomileusis (LASIK) to optimize the performance of the contact lenses...
  101. ncbi Wavefront aberrations from corneal ectasia after laser in situ keratomileusis demonstrated by InterWave aberrometry
    J Bradley Randleman
    Emory University, Department of Ophthalmology, Atlanta, GA, USA
    J Refract Surg 20:170-5. 2004
    ..The patient presented with minimal alterations in manifest refraction but had obvious distortions in the wavefront error of the eye, as demonstrated by InterWave aberrometry...

Research Grants93

  1. Neonatal Bladder Inflammation, Opioids, and Adult Bladder Pain
    Alan Randich; Fiscal Year: 2010
    ....
  2. Neonatal Bladder Inflammation, Opioids, and Adult Bladder Pain
    Alan Randich; Fiscal Year: 2008
    ....
  3. Early-In-Life Inflammation Effects on Urinary Bladder Sensation
    Alan Randich; Fiscal Year: 2008
    ..Translation to the treatment of painful bladder syndromes like 1C would be highly probable. ..
  4. Early-In-Life Inflammation Effects on Urinary Bladder Sensation
    Alan Randich; Fiscal Year: 2009
    ..Translation to the treatment of painful bladder syndromes like 1C would be highly probable. ..
  5. Neonatal Bladder Inflammation, Opioids, and Adult Bladder Pain
    Alan Randich; Fiscal Year: 2009
    ....
  6. Effects of early-in-life bladder stimulation on adults
    Alan Randich; Fiscal Year: 2004
    ..Translation to the treatment of IC would be highly probable. ..
  7. Neonatal Bladder Inflammation, Opioids, and Adult Bladder Pain
    Alan Randich; Fiscal Year: 2010
    ....
  8. Early-In-Life Inflammation Effects on Urinary Bladder Sensation
    Alan Randich; Fiscal Year: 2007
    ..Translation to the treatment of painful bladder syndromes like 1C would be highly probable. ..
  9. CRF2 Receptor Modulation of Colonic Response to Stress
    MILLION MULUGETA; Fiscal Year: 2006
    ..abstract_text> ..
  10. SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONS
    William Willis; Fiscal Year: 2006
    ..Preliminary evidence supports the feasibility of the work and suggests that the results could lead to a number of new targets for improvements in pain therapy. ..
  11. Myocardial Viability and Remodeling in the OAT
    James Udelson; Fiscal Year: 2007
    ..OAT-NUC is the only viability ancillary study of OAT, and thus serves a critical need in assessing potential mechanisms of the findings in OAT. ..
  12. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  13. Myocardial Viability and Remodeling in the OAT
    James Udelson; Fiscal Year: 2006
    ..OAT-NUC is the only viability ancillary study of OAT, and thus serves a critical need in assessing potential mechanisms of the findings in OAT. ..
  14. Highly Automated Analysis of 4-D Cardiovascular MR Data
    Milan Sonka; Fiscal Year: 2005
    ..The relationship between disease status, standard measures of ventricular function and aortic size, and novel quantitative indices will be assessed. ..
  15. VEGF regulation of surfactant proteins in preventing RSV
    DAVID MEYERHOLZ; Fiscal Year: 2005
    ....
  16. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  17. STRENGTH TRAINING FOLLOWING GASTRIC BYPASS FOR OBESITY
    Allan Geliebter; Fiscal Year: 2004
    ..The findings should improve understanding of surgical weight loss in morbidly obese patients and have clinical applications in the postoperative care of such patients. ..
  18. Muscle-Powered VAD Chronic Studies in Conscious Animal
    James Magovern; Fiscal Year: 2004
    ..The applicants further expect that practical application of this technology will have been demonstrated via implant testing of a complete muscle-actuated ventricular assist system. ..
  19. Graph-Based Medical Image Segmentation in 3D and 4D
    Milan Sonka; Fiscal Year: 2006
    ..Image analysis methods such as proposed here allow evaluating the image data objectively in a quantitative manner, promising to substantially impact image-based clinical care. [unreadable] [unreadable] [unreadable]..
  20. Computer-Aided Interpretation of Oculometric Data
    Michael Smolek; Fiscal Year: 2004
    ..For patients, refractive surgery outcomes will be more predictable, and they will benefit from earlier detection of diseases such as cataracts and corneal ectasias. ..
  21. In vivo multichannel fluorescent imaging
    Umar Mahmood; Fiscal Year: 2007
    ....
  22. SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONS
    William Willis; Fiscal Year: 2007
    ..Preliminary evidence supports the feasibility of the work and suggests that the results could lead to a number of new targets for improvements in pain therapy. ..
  23. Functional Brain Imaging and Appetite-Related Hormones Pre and Post Obesity Surge
    Allan Geliebter; Fiscal Year: 2010
    ..The findings may also improve our understanding of the causes of obesity, which could lead to new less invasive treatments. ..
  24. GENETIC FACTORS IN KERATOCONUS
    Yaron Rabinowitz; Fiscal Year: 2009
    ..Ultimately, this work may improve our ability to treat KC and/or prevent the development of KC. ..
  25. Neuroprotection with serpins during cardiac surgery
    Richard A Jonas; Fiscal Year: 2010
    ..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..
  26. MOLECULAR PHYSIOLOGY OF MYOCARDIAL TROPONIN I VARIANTS
    Anne Murphy; Fiscal Year: 2008
    ..In the long-term this will assist in the development of novel therapies which address the correction of myofilament defects. ..
  27. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2009
    ..We will determine how these proteins are modified by the same processes as found in the diseases states and then test the effects they have on vascular ion channels and blood vessel function. ..
  28. Cellular Mechanisms of Lymphatic Muscle Contractility
    Michael Davis; Fiscal Year: 2009
    ..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..
  29. INTEGRATED ASSESSMENT OF CORNEAL FORM AND FUNCTION
    STEPHEN KLYCE; Fiscal Year: 2000
    ..This is combined with methods to classify shape anomalies and means to assess the optical quality of the corneal surface through the analysis of corneal topography. ..
  30. Neuronal Changes in Adult Rats Induced by Neonatal Pain
    Adrian Miranda; Fiscal Year: 2008
    ..This study will be the first systematic evaluation of chronic visceral hyperalgesia that results from a non-inflammatory somatic stimulus in early life. ..
  31. Modulation of Colonic Response to Stress by Peripheral CRF2 Receptors
    MILLION MULUGETA; Fiscal Year: 2008
    ....
  32. Neuroprotection with serpins during cardiac surgery
    Richard Jonas; Fiscal Year: 2008
    ..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..
  33. Graph-Based Medical Image Segmentation in 3D and 4D
    Milan Sonka; Fiscal Year: 2008
    ..Image analysis methods such as proposed here allow evaluating the image data objectively in a quantitative manner, promising to substantially impact image-based clinical care. ..
  34. Extracellular Mechanisms For Thoracic Aortic Aneurysms
    John Ikonomidis; Fiscal Year: 2008
    ..abstract_text> ..
  35. 3D & 4D CORONARY HEMODYNAMICS AND LOCAL ATHEROSCLEROSIS
    Milan Sonka; Fiscal Year: 2008
    ..It will have implications on the clinical management of patients with preclinical atherosclerotic disease as well as those patients undergoing coronary revascularization and treatment of acute coronary syndromes. ..
  36. Cloning/Gene/Posterior Polymorphous corneal dystrophy
    ANTHONY ALDAVE; Fiscal Year: 2007
    ....
  37. Extracellular Mechanisms For Thoracic Aortic Aneurysms
    John Ikonomidis; Fiscal Year: 2004
    ..abstract_text> ..
  38. SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONS
    William Willis; Fiscal Year: 1999
    ..This mechanisms resembles long-term depression in the brain. The overall goal of the project is to learn more about the endogenous analgesia systems so that improvements can be made in the treatment of pain. ..
  39. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 2000
    ....
  40. SHEAR STRESS INDUCED RELEASE OF ENDOTHELIAL NITRIC OXIDE
    Michael Davis; Fiscal Year: 2000
    ....
  41. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 1993
    ..The results of these experiments will provide new insights into the mechanism and function of the myogenic response at the network, single vessel, and cellular levels...
  42. SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONS
    William Willis; Fiscal Year: 1980
    ..The work should have relevance to the field of pain mechanisms. ..
  43. SYNAPTIC CONNECTIONS OF SPINAL CORD NEURONS
    William Willis; Fiscal Year: 1991
    ..It is hoped that the results of these studies will be useful for a better understanding of pain mechanisms and of pain therapy in humans...
  44. 3D & 4D CORONARY HEMODYNAMICS AND LOCAL ATHEROSCLEROSIS
    Milan Sonka; Fiscal Year: 2002
    ..abstract_text> ..
  45. MUSCLE POWERED VAD (VENTRICULAR ASSIST DEVICE)--CHRONIC
    James Magovern; Fiscal Year: 2000
    ..The applicants further expect that practical application of this technology will have been demonstrated via implant testing of a complete muscle-actuated ventricular assist system. ..
  46. Computer-Aided Interpretation of Oculometric Data
    Michael Smolek; Fiscal Year: 2003
    ..For patients, refractive surgery outcomes will be more predictable, and they will benefit from earlier detection of diseases such as cataracts and corneal ectasias. ..
  47. Calorie Restriction Effects on Chromosomal Aberrations
    CHARLEEN MOORE; Fiscal Year: 2003
    ..The results will be essential in identifying potential mechanisms by which CR acts in cancer prevention and delay of the aging process in long-lived species such as the rhesus monkey and humans. ..
  48. MUSCLE POWERED VAD (VENTRICULAR ASSIST DEVICE)--CHRONIC
    James Magovern; Fiscal Year: 1999
    ..The applicants further expect that practical application of this technology will have been demonstrated via implant testing of a complete muscle-actuated ventricular assist system. ..
  49. NIRS FOR BRAIN MONITORING IN CARDIAC SURGERY
    Richard Jonas; Fiscal Year: 1999
    ..It also will demonstrate the utility of near infrared spectroscopy as a clinical method for avoid brain injury during pediatric cardiac surgery. ..
  50. INTEGRATED ASSESSMENT OF CORNEAL FORM AND FUNCTION
    STEPHEN KLYCE; Fiscal Year: 2002
    ..abstract_text> ..
  51. In vivo multichannel fluorescent imaging
    Umar Mahmood; Fiscal Year: 2006
    ....
  52. Cellular Mechanisms of Lymphatic Muscle Contractility
    Michael Davis; Fiscal Year: 2008
    ..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..
  53. Neuroprotection with serpins during cardiac surgery
    Richard Jonas; Fiscal Year: 2009
    ..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..
  54. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2010
    ..These studies will investigate which proteins allow these vessels to contract so that specific therapeutic agents can be developed to correct lymphatic pump dysfunction and drainage of edematous tissues. ..
  55. Protection of Developing White Matter during Cardiac Surgery
    Richard A Jonas; Fiscal Year: 2010
    ..This study will investigate how inflammation caused by the heart-lung machine selectively damages cerebral white matter which plays a key role in the development of motor skills. ..
  56. The Predictive Value of Pre-plus Disease in ROP
    David Wallace; Fiscal Year: 2008
    ..abstract_text> ..
  57. The Predictive Value of Pre-plus Disease in ROP
    David Wallace; Fiscal Year: 2007
    ..abstract_text> ..
  58. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 2002
    ....
  59. Cerebral Oxygeneration During Cardiopulmonary Bypass
    Richard Jonas; Fiscal Year: 2002
    ..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..
  60. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2003
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  61. Cerebral Oxygeneration During Cardiopulmonary Bypass
    Richard Jonas; Fiscal Year: 2003
    ..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..
  62. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2004
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  63. Cerebral Oxygeneration During Cardiopulmonary Bypass
    Richard Jonas; Fiscal Year: 2004
    ..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..
  64. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2004
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. ..
  65. In vivo multichannel fluorescent imaging
    Umar Mahmood; Fiscal Year: 2003
    ....
  66. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2003
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  67. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2005
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  68. Cerebral Oxygeneration During Cardiopulmonary Bypass
    Richard Jonas; Fiscal Year: 2001
    ..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..
  69. Neuroprotection with serpins during cardiac surgery
    Richard Jonas; Fiscal Year: 2007
    ..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..
  70. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 1992
    ..The results of these experiments will provide new insights into the mechanism and function of the myogenic response at the network, single vessel, and cellular levels...
  71. MECHANISM AND FUNCTION OF THE VASCULAR MYOGENIC RESPONSE
    Michael Davis; Fiscal Year: 2001
    ....
  72. Regulation of Arteriolar Tone & K Channels by Integrins
    Michael Davis; Fiscal Year: 2006
    ..In addition, our results will establish a paradigm for understanding how other ion channels in other tissues may be regulated by integrins. ..
  73. SHEAR STRESS INDUCED RELEASE OF ENDOTHELIAL NITRIC OXIDE
    Michael Davis; Fiscal Year: 2001
    ....
  74. NIRS FOR BRAIN MONITORING IN CARDIAC SURGERY
    Richard Jonas; Fiscal Year: 2000
    ..It also will demonstrate the utility of near infrared spectroscopy as a clinical method for avoid brain injury during pediatric cardiac surgery. ..
  75. In vivo multichannel fluorescent imaging
    Umar Mahmood; Fiscal Year: 2004
    ....
  76. Regulation of Vascular Tone and Ca channels by Integrins
    Michael Davis; Fiscal Year: 2006
    ..In addition, elucidation of a signal transduction pathway between the CaL channel and beta1 integrins will establish a general paradigm for how ion channels are regulated by integrins and ECM. [unreadable] [unreadable]..
  77. In vivo multichannel fluorescent imaging
    Umar Mahmood; Fiscal Year: 2005
    ....
  78. Cerebral Oxygeneration During Cardiopulmonary Bypass
    Richard Jonas; Fiscal Year: 2003
    ..By enhancing understanding of mechanisms of cardiopulmonary bypass-related brain injury it will facilitate development of novel pharmacologic methods to further reduce the risk of brain damage. ..