Genomes and Genes
Summary: A catarrhal disorder of the upper respiratory tract, which may be viral, a mixed infection, or an allergic reaction. It is marked by acute coryza, slight rise in temperature, chilly sensations, and general indisposition. (Dorland, 27th ed)
Publications252 found, 100 shown here
- Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetateAnanda S Prasad
Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Infect Dis 197:795-802. 2008Zinc lozenges have been used for treatment of the common cold; however, the results remain controversial.
- Social ties and susceptibility to the common coldS Cohen
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
JAMA 277:1940-4. 1997..To examine the hypothesis that diverse ties to friends, family, work, and community are associated with increased host resistance to infection...
- The common coldTerho Heikkinen
Department of Paediatrics, Turku University Hospital, Turku, Finland
Lancet 361:51-9. 2003Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the several viruses that cause the disease, the role of rhinoviruses is most prominent...
- Perception of empathy in the therapeutic encounter: effects on the common coldDavid Rakel
Department of Family Medicine, University of Wisconsin Madison, Madison, WI, USA
Patient Educ Couns 85:390-7. 2011To evaluate the effects of patient-practitioner interaction on the severity and duration of the common cold.
- Treatment of the common coldMadeline Simasek
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Am Fam Physician 75:515-20. 2007The common cold is a viral illness that affects persons of all ages, prompting frequent use of over-the-counter and prescription medications and alternative remedies. Treatment focuses on relieving symptoms (e.g...
- Understanding the symptoms of the common cold and influenzaRon Eccles
Common Cold Centre, Cardiff School of Biosciences, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
Lancet Infect Dis 5:718-25. 2005The common cold and influenza (flu) are the most common syndromes of infection in human beings...
- Vitamin C for preventing and treating the common coldHarri Hemilä
Department of Public Health, POB 41, University of Helsinki, Helsinki, Finland
Cochrane Database Syst Rev 1:CD000980. 2013Vitamin C (ascorbic acid) for preventing and treating the common cold has been a subject of controversy for 70 years.
- Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physiciansR Gonzales
Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
JAMA 278:901-4. 1997..How frequently antibiotics are prescribed for these conditions and for and by whom is not known...
- Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common coldHong Jun Cho
Department of Family Medicine, University of Ulsan College of Medicine, Songpa P O Box 145, Seoul 138 736, South Korea
Soc Sci Med 58:623-9. 2004..practitioners and pediatricians), pharmacists, and parents regarding the use of antibiotics for the pediatric common cold, using a self-administered questionnaire for physicians and pharmacists and a telephone interview for parents...
- Consumer attitudes and use of antibioticsJodi Vanden Eng
Connecticut Emerging Infections Program, New Haven 06510, USA
Emerg Infect Dis 9:1128-35. 2003..National educational efforts are needed to address these issues if patient demand for antibiotics is to be reduced...
- Epidemiological relationships between the common cold and exacerbation frequency in COPDJ R Hurst
Academic Unit of Respiratory Medicine, Royal Free and University College Medical School, Hampstead, London, NW3 2QG, UK
Eur Respir J 26:846-52. 2005..Exacerbation frequency in chronic obstructive pulmonary disease is associated with an increased frequency of acquiring the common cold, rather than an increased propensity to exacerbation once a cold has been acquired.
- Practitioner empathy and the duration of the common coldDavid P Rakel
School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA
Fam Med 41:494-501. 2009This study's objective was to assess the relationship of empathy in medical office visits to subsequent outcomes of the common cold.
- Viruses and bacteria in the etiology of the common coldM J Mäkelä
Department of Pediatrics, University of Turku, Finland
J Clin Microbiol 36:539-42. 1998..The results show that although approximately 50% of episodes of the common cold were caused by rhinoviruses, the etiology can vary depending on the epidemiological situation with regard to ..
- Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infectionK Grunberg
Department of Pulmonology, Department of Medical Decision Making, Leiden University Medical Center LUMC, Leiden, The Netherlands
Am J Respir Crit Care Med 164:1816-22. 2001..The latter finding is in keeping with the limited protection of inhaled corticosteroids against acute asthma exacerbations...
- Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort studyJonathan M Corne
University Medicine, Southampton General Hospital, Southampton, UK
Lancet 359:831-4. 2002..Rhinovirus infections cause exacerbations of asthma. We postulated that people with asthma are more susceptible to rhinovirus infection than people without the disease and compared the susceptibility of these groups...
- Complementary and alternative medicine for prevention and treatment of the common coldRichard Nahas
Seekers Centre for Integrative Medicine, Ottawa, ON
Can Fam Physician 57:31-6. 2011To review the evidence supporting complementary and alternative medicine approaches to treatment and prevention of the common cold in adults.
- Echinacea for treating the common cold: a randomized trialBruce Barrett
Department of Family Medicine, University of Wisconsin, Madison, Wisconsin 53715, USA
Ann Intern Med 153:769-77. 2010Echinacea is widely used to treat the common cold.
- Mega-dose vitamin C in treatment of the common cold: a randomised controlled trialC Audera
National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT
Med J Aust 175:359-62. 2001OBJECTIVE: To determine the effect of large doses of vitamin C in the treatment of the common cold. STUDY DESIGN: Double-blind, randomised clinical trial with four intervention arms: vitamin C at daily doses of 0...
- Reduction of common cold symptoms by encapsulated juice powder concentrate of fruits and vegetables: a randomised, double-blind, placebo-controlled trialStephanie Roll
Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Centre, Luisenstrasse 57, 10098 Berlin, Germany
Br J Nutr 105:118-22. 2011Dietary supplements have been suggested in the prevention of the common cold, but previous investigations have been inconsistent...
- Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trialMichael de Vrese
Institute of Physiology and Biochemistry of Nutrition, Federal Research Centre of Nutrition and Food, Hermann Weigmann Strasse 1, D 24103 Kiel, Germany
Vaccine 24:6670-4. 2006To investigate the effect of long-term consumption of probiotic bacteria on viral respiratory tract infections (common cold, influenza), a randomized, double blind, controlled intervention study was performed during two winter/spring ..
- Dynamics of human respiratory virus-specific CD8+ T cell responses in blood and airways during episodes of common coldJojanneke Heidema
Division of Paediatrics, Wilhelmina Children s Hospital, Utrecht, The Netherlands
J Immunol 181:5551-9. 2008..Taken together, these results showed a significant systemic T cell response during relatively mild secondary infections and extensive dynamics of virus-specific and nonspecific Ag-experienced T cells...
- Relations among questionnaire and laboratory measures of rhinovirus infectionB Barrett
University of Wisconsin Medical School, 777 S Mills, Madison, WI 53715, USA
Eur Respir J 28:358-63. 2006..The inclusion of functional and quality-of-life items in the Wisconsin Upper Respiratory Symptom Survey does not significantly decrease the strength of association with laboratory-assessed biomarkers...
- Misconceptions about colds and predictors of health service utilizationGrace M Lee
Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
Pediatrics 111:231-6. 2003..The objective of this study was to determine predictors of reported ED use and ambulatory care use for colds among families with young children...
- Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjectsMichelle L Seymour
Division of Respiratory Cell and Molecular Biology, University of Southampton School of Medicine, Southampton, United Kingdom
J Infect Dis 185:540-4. 2002..13). Cold symptom scores correlated with bronchial immunostaining for FLAP (rho = 0.93; P =.001). In normal subjects, rhinovirus colds induce bronchial inflammation with markedly enhanced expression of 5-LO pathway proteins and COX-2...
- Nasal inflammation induced by a common cold: comparison between controls and patients with nasal polyposis under topical steroid therapyC Dassonville
Laboratory of Public Health and Environment, Faculty of Pharmacy, University Paris V, Paris
Acta Otorhinolaryngol Ital 27:78-82. 2007The evolution of nasal inflammation during a common cold in patients with nasal polyposis under topical steroid treatment is not clearly defined in the literature...
- Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonistsRolf P Kreutz
Sinai Center for Thrombosis Research, Baltimore, Maryland 21215, USA
Blood Coagul Fibrinolysis 18:713-8. 2007..We hypothesized that changes in platelet activation and reactivity and inflammation occur during the 'common cold'. Previously healthy individuals with viral upper respiratory tract infections were studied (n = 18)...
- Influence of attendance at day care on the common cold from birth through 13 years of ageThomas M Ball
Department of Pediatrics, University of Arizona College of Medicine, 1501 N Campbell Ave, PO Box 245073, Tucson, AZ 85724 5073, USA
Arch Pediatr Adolesc Med 156:121-6. 2002To describe trends in the occurrence of the common cold during the first 13 years of life among children who attended different childcare settings early in life.
- Transmission of viral respiratory infections in the homeD A Goldmann
Department of Medicine Children s Hospital, Boston, MA 02115, USA
Pediatr Infect Dis J 19:S97-102. 2000..study, from the plains of Salisbury, to the hills of Virginia, to the collegiate environment of Madison, WI, the precise routes rhinovirus takes to inflict the misery of the common cold on a susceptible population remain controversial.
- Weekly monitoring of children with asthma for infections and illness during common cold seasonsJaime P Olenec
Department of Pediatrics, University of Wisconsin, Madison, WI 53792 4108, USA
J Allergy Clin Immunol 125:1001-1006.e1. 2010..Exacerbations of childhood asthma and rhinovirus infections both peak during the spring and fall, suggesting that viral infections are major contributors to seasonal asthma morbidity...
- The treatment of rhinovirus infections: progress and potentialR B Turner
Department of Pediatrics, Medical University of South Carolina, Clinical Sciences Building, Room 312, 171 Ashley Avenue, Charleston, SC 29425, USA
Antiviral Res 49:1-14. 2001The common cold is an important illness both as a result of the economic impact of this common disease and because of the morbidity associated with the complications of the illness...
- Iota-Carrageenan is a potent inhibitor of rhinovirus infectionAndreas Grassauer
Marinomed Biotechnologie GmbH, Veterinaerplatz 1 HA, A 1210 Vienna, Austria
Virol J 5:107. 2008Human rhinoviruses (HRVs) are the predominant cause of common cold. In addition, HRVs are implicated in the worsening of COPD and asthma, as well as the loss of lung transplants...
- Vitamin E and respiratory tract infections in elderly nursing home residents: a randomized controlled trialSimin Nikbin Meydani
Nutritional Immunology Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Mass 02111, USA
JAMA 292:828-36. 2004..Vitamin E supplementation has been shown to improve immune response in elderly persons. However, the clinical importance of these findings has not been determined...
- Psychological stress and susceptibility to the common coldS Cohen
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213
N Engl J Med 325:606-12. 1991..To investigate this issue, we prospectively studied the relation between psychological stress and the frequency of documented clinical colds among subjects intentionally exposed to respiratory viruses...
- Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trialMichael de Vrese
Institute for Physiology and Biochemistry of Nutrition, Federal Research Centre of Nutrition and Food, Hermann Weigmann Strasse 1, D 24103 Kiel, Germany
Clin Nutr 24:481-91. 2005..bifidum MF 20/5 (5 x 10(7) cfu/tablet) during at least 3 months influences the severity of symptoms and the incidence and duration of the common cold.
- Rhinovirus infections: more than a common coldMarc B Hershenson
Am J Respir Crit Care Med 174:1284-5. 2006
- Symptom severity patterns in experimental common colds and their usefulness in timing onset of illness in natural coldsJack M Gwaltney
Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville 22908, USA
Clin Infect Dis 36:714-23. 2003..5% of natural colds on day 1 of illness. Histories given by compensated patients in natural cold treatment trials are inaccurate...
- A multicultural approach to the patient who has a common coldWilliam F Pfeiffer
Pediatric Department, Kaiser Permanente Honolulu Clinic, Honolulu, Hawaii, USA
Pediatr Rev 26:170-5. 2005
- Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infectionsVille Peltola
Department of Pediatrics, Turku University Hospital, Turku, Finland
J Infect Dis 197:382-9. 2008..Rhinoviruses are the most common cause of respiratory tract infections, but the transmission in families has not been studied using sensitive and specific molecular detection methods...
- Cytokine responses in the common cold and otitis mediaTodd M Wine
Division of Pediatric Otolaryngology, Children s Hospital of Pittsburgh of UPMC, Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Curr Allergy Asthma Rep 12:574-81. 2012..The common cold and otitis media are two such disease states, and much has been learned about the various effects of cytokines ..
- Allergic rhinitis and the common cold--high cost to societyJ Hellgren
Department of Otorhinolaryngology, Head and Neck Surgery, Capio Lundby Hospital, Wieselgrensplatsen 2A, Goteborg, Sweden
Allergy 65:776-83. 2010The common cold and allergic rhinitis constitute a global health problem that affects social life, sleep, school and work performance and is likely to impose a substantial economic burden on society because of absence from work and ..
- Patient beliefs about the characteristics, causes, and care of the common cold: an updateB L Braun
Health Research Center, Institute for Research and Education, HealthSystem Minnesota, Minneapolis 55416, USA
J Fam Pract 49:153-6. 2000..Many people seek medical care for cold symptoms. The cold-related knowledge and beliefs of adults seeking medical care for themselves or their children may not correspond with current medical opinion...
- Use of surgical face masks to reduce the incidence of the common cold among health care workers in Japan: a randomized controlled trialJoshua L Jacobs
University of Hawaii John A Burns School of Medicine, Honolulu, HI, USA
Am J Infect Control 37:417-9. 2009..Health care workers outside surgical suites in Asia use surgical-type face masks commonly. Prevention of upper respiratory infection is one reason given, although evidence of effectiveness is lacking...
- Validity of the common cold questionnaire (CCQ) in asthma exacerbationsHeather Powell
Department of Respiratory and Sleep Medicine, Hunter Medical Research Institute, John Hunter Hospital, New Lambton, New South Wales, Australia
PLoS ONE 3:e1802. 2008The common cold questionnaire (CCQ) is used to discriminate those with and without a viral infection. Its usefulness in people with acute asthma is unknown...
- Combined antiviral-antimediator treatment for the common coldJack M Gwaltney
Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
J Infect Dis 186:147-54. 2002..IFN-alpha2b added to the effectiveness of chlorpheniramine and ibuprofen and was well tolerated...
- Antibiotics for the common cold and acute purulent rhinitisTim Kenealy
Department of General Practice and Primary Health Care, University of Auckland, Auckland, New Zealand
Cochrane Database Syst Rev 6:CD000247. 2013..It has long been believed that antibiotics have no role in the treatment of common colds yet they are often prescribed in the belief that they may prevent secondary bacterial infections...
- Effect of vitamin C on common cold: randomized controlled trialS Sasazuki
Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Chuo Ku, Tokyo, Japan
Eur J Clin Nutr 60:9-17. 2006To investigate the relationship between the common cold and vitamin C supplementation.
- Testing of cough reflex sensitivity in children suffering from allergic rhinitis and common coldJ Plevkova
Department of Pathophysiology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia
J Physiol Pharmacol 57:289-96. 2006..Cough also is enhanced by acute inflammation in the upper airways in nonatopic children...
- Effects of intranasal xylometazoline, alone or in combination with ipratropium, in patients with common coldRonald Eccles
Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
Curr Med Res Opin 26:889-99. 2010b>Common cold is one of the most prevalent conditions that family doctors encounter...
- Rhinoviruses: important respiratory pathogensA Pitkaranta
Department of Otorhinolaryngology, Helsinki University Central Hospital, Finland
Ann Med 30:529-37. 1998..However, the high incidence of HRV infections and their frequent association with upper and lower respiratory tract complications highlight the need for more effective means of prevention and treatment...
- Visiting a sauna: does inhaling hot dry air reduce common cold symptoms? A randomised controlled trialDaniel Pach
Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
Med J Aust 193:730-4. 2010To compare the efficacy of applying hot dry air versus dry air at room temperature to the throat of patients with a newly acquired common cold using a symptom severity score.
- [Common cold--risk factors, transmission and treatment]H Herløv-Nielsen
H S Rigshospitalet, Finsencentret, epidemiklinikken
Ugeskr Laeger 163:5643-6. 2001The common cold is the most prevalent disease in humans. It is generally caused by rhinovirus. Bacterial involvement is rare, and an uncomplicated common cold does not require treatment with antibiotics...
- [Common cold]J Padberg
HELIOS Klinikum Emil von Behring, Zentrum für Pneumologie und Thoraxchirurgie Heckeshorn
Dtsch Med Wochenschr 131:2341-9; quiz 2351-2. 2006
- The effects of a hot drink on nasal airflow and symptoms of common cold and fluA Sanu
Common Cold Centre and Healthcare Clinical Trials, Cardiff School of Biosciences, Cardiff University, Cardiff, United Kingdom
Rhinology 46:271-5. 2008Hot drinks are a common treatment for common cold and flu but there are no studies reported in the scientific and clinical literature on this mode of treatment...
- Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteersFrederick G Hayden
Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
Antimicrob Agents Chemother 47:3907-16. 2003..Results from these studies in experimental rhinoviral infection support continued investigation of intranasal ruprintrivir in the setting of natural HRV infection...
- Role of nasopharyngeal culture in antibiotic prescription for patients with common cold or acute sinusitisL Kaiser
Division of Infectious Diseases, University Hospital of Geneva, Switzerland
Eur J Clin Microbiol Infect Dis 20:445-51. 2001..Adults with a clinical diagnosis of acute sinusitis or common cold were enrolled...
- Acute cooling of the feet and the onset of common cold symptomsClaire Johnson
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
Fam Pract 22:608-13. 2005There is a common folklore that chilling of the body surface causes the development of common cold symptoms, but previous clinical research has failed to demonstrate any effect of cold exposure on susceptibility to infection with common ..
- Complementary treatment of the common cold and flu with medicinal plants--results from two samples of pharmacy customers in EstoniaAin Raal
Department of Pharmacy, University of Tartu, Tartu, Estonia
PLoS ONE 8:e58642. 2013The aim of the current survey was to investigate the complementary self-treatment of the common cold and flu with medicinal plants among pharmacy customers in Estonia...
- Viral respiratory infections due to rhinoviruses: current knowledge, new developmentsA Mark Fendrick
Department of Internal Medicine, School of Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Ther 10:193-202. 2003..By targeting the cause of illness, antiviral agents represent an opportunity to reduce the substantial clinical burden of VRI. Furthermore, effective therapies can potentially reduce inappropriate antibiotic use for viral infections...
- A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytesMariana Mesel-Lemoine
Unité de Génomique Virale et Vaccination, Department of Virology, Institut Pasteur, CNRS URA 3015, Paris, France
J Virol 86:7577-87. 2012....
- Capturing the onset of the common cold and its effects on iron absorptionM Hoppe
Department of Clinical Nutrition, Institute of Internal Medicine, The Sahlgrenska Academy at Goteborg University, S 405 30 Gothenburg, Sweden
Eur J Clin Nutr 61:1032-4. 2007..However, to our best knowledge there are no previous published reports on the outbreak of a common cold and its initial effect on iron kinetics. The objective of this case report is to describe such an observation...
- Efficacy and safety of over-the-counter analgesics in the treatment of common cold and fluR Eccles
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
J Clin Pharm Ther 31:309-19. 2006b>Common cold and flu are the most common human illnesses, and over-the-counter (OTC) analgesics are widely used to treat the pain and fever symptoms...
- Safety and efficacy evaluation of pleconaril for treatment of the common coldRussell Fleischer
Clin Infect Dis 37:1722. 2003
- Predicting worsening asthma control following the common coldM J Walter
Division of Pulmonary and Critical Care Medicine, Campus Box 8052, 660 South Euclid Ave, St Louis, MO 63110, USA
Eur Respir J 32:1548-54. 2008The asthmatic response to the common cold is highly variable, and early characteristics that predict worsening of asthma control following a cold have not been identified...
- Treatment of the common cold with echinacea: a structured reviewThomas J Caruso
Stanford University School of Medicine, Stanford, CA, USA
Clin Infect Dis 40:807-10. 2005Echinacea is a herbal preparation that is frequently used to treat the common cold. Spending on echinacea in the United States has risen to >300 million dollars annually.
- Safety and efficacy of over-the-counter cough and cold medicines for use in childrenZdravko P Vassilev
Epidemiology, Covance Periapproval Services, 555 North Lane, Suite 6000, Conshohocken, PA, USA
Expert Opin Drug Saf 9:233-42. 2010....
- Placebo effects and the common cold: a randomized controlled trialBruce Barrett
University of Wisconsin, Madison, Madison, Wisconsin, USA
Ann Fam Med 9:312-22. 2011We wanted to determine whether the severity and duration of illness caused by the common cold are influenced by randomized assignment to open-label pills, compared with conventional double-blind allocation to active and placebo pills, ..
- Herbs and other dietary supplements: current regulations and recommendations for use to maintain health in the management of the common cold or other related infectious respiratory illnessesAngelo Mathes
Consultation Angelo Inc, Town of Mount Royal, QC, Canada
J Pharm Pract 23:117-27. 2010..The common cold is an important illness due to its recurring nature, the number of people it afflicts, and its economic impact ..
- Aircraft cabin air recirculation and symptoms of the common coldJessica Nutik Zitter
Department of Medicine, University of California, San Francisco, Box 0843, San Francisco, CA 94143 0843, USA
JAMA 288:483-6. 2002..Whether air recirculation increases the transmission of infectious disease is unknown; some studies have demonstrated higher rates of the common cold among persons working in buildings that recirculate air.
- Effects of So-cheong-ryong-tang and Yeon-gyo-pae-dok-san on the common cold: randomized, double blind, placebo controlled trialJun Seop Byun
Department of Internal Medicine, Oriental Medical College of Daejeon University, 96 3 Yongwun dong, Daejeon 300 716, South Korea
J Ethnopharmacol 133:642-6. 2011So-cheong-ryong-tang (SCRT) and Yeon-gyo-pae-dok-san (YPS) extracts are widely used in treatment of the common cold. The purpose of this study is to evaluate the efficacy of SCRT and YPS on the common cold.
- Problems and prospects of developing effective therapy for common cold virusesS L Johnston
University Medicine, Southampton General Hospital, UK
Trends Microbiol 5:58-63. 1997..These approaches offer new avenues for treating populations at risk and are of particular significance to those with asthma or chronic bronchitis...
- Intake of wine, beer, and spirits and the risk of clinical common coldBahi Takkouche
Department of Preventive Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain
Am J Epidemiol 155:853-8. 2002To examine whether intakes of wine, beer, spirits, and total alcohol are associated with the risk of common cold, in 1998-1999 the authors analyzed data from a cohort study carried out in a population of 4,272 faculty and staff of five ..
- Hydrogen peroxide in breath condensate during a common coldR Q Jöbsis
Department of Paediatrics, Division of Paediatric Respiratory Medicine, Erasmus University Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
Mediators Inflamm 10:351-4. 2001..Hydrogen peroxide (H2O2) in exhaled air condensate is elevated in inflammatory disorders of the lower respiratory tract. It is unknown whether viral colds contribute to exhaled H2O2...
- The incidence, prevalence and burden of OM in unselected children aged 1-8 years followed by weekly otoscopy through the "common cold" seasonEllen M Mandel
Department of Otolaryngology, Children s Hospital of Pittsburgh and the University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
Int J Pediatr Otorhinolaryngol 72:491-9. 2008..Often overlooked in past studies are the contributions of cold-like illnesses (CLIs) and sampling interval to those estimates...
- Respiratory consequences of rhinovirus infectionStephen B Greenberg
Department of Internal Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
Arch Intern Med 163:278-84. 2003..By altering the clinical course of picornavirus infections, it may be possible to minimize their potential adverse consequences...
- Efficacy of a pelargonium sidoides preparation in patients with the common cold: a randomized, double blind, placebo-controlled clinical trialViktor G Lizogub
Faculty Therapy No 2, National Medical University, Kiev, Ukraine
Explore (NY) 3:573-84. 2007The common cold is a viral infection with symptoms such as sneezing, sore throat, and running nose...
- Evidence for correlation of objective and subjective measures of nasal airflow in patients with common coldJ D Clarke
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
Clin Otolaryngol 30:35-8. 2005..To utilize posterior rhinomanometry and conductance, as units of measurement, to further investigate the relationship between subjective and objective measures of nasal airflow...
- A clinical trial of hypertonic saline nasal spray in subjects with the common cold or rhinosinusitisP Adam
Riverside University Family Practice Clinic, University of Minnesota Department of Family Practice and Community Health, Minneapolis 55406, USA
Arch Fam Med 7:39-43. 1998To determine whether hypertonic saline nasal spray relieves nasal symptoms and shortens illness duration in patients with the common cold or acute rhinosinusitis.
- [Cough induction by high-frequency chest percussion in healthy volunteers and patients with common cold]P C L Lee
Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
Respir Med 98:771-6. 2004..The aim of this study was to determine if cough can be induced by high-frequency chest percussion in healthy subjects and in patients with acute upper respiratory tract infection (URTI)...
- Visits by adults to family physicians for the common coldW J McIsaac
Mt Sinai Family Medicine Centre, Toronto, Ontario, Canada
J Fam Pract 47:366-9. 1998..We examined how often a large population of adults visited doctors when they had a cold, the degree to which they engaged in self care, and the characteristics of those seeking care...
- Echinacea for preventing and treating the common coldKarin Woelkart
Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl Franzens University, Graz, Austria
Planta Med 74:633-7. 2008Echinacea preparations are widely used for common cold. Many consumers and healthcare professionals are not aware that products available under the term Echinacea may differ in their composition, due to the use of different species, ..
- Willingness to pay for health care services in common cold, retinal detachment, and myocardiac infarction: an internet survey in JapanHideo Yasunaga
Department of Planning, Information and Management, University of Tokyo Hospital, Tokyo, Japan
BMC Health Serv Res 6:12. 2006..The objective of this survey is to measure WTP for the treatment of typical acute illnesses and to analyze the factors affecting WTP...
- The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in childrenZafer Kurugol
Department of Paediatrics, Faculty of Medicine, Ege University, Izmir, Turkey
Acta Paediatr 95:1175-81. 2006To determine the efficacy of prophylactic administration of zinc sulphate in reducing the occurrence of the common cold in children, and to evaluate the efficacy of zinc sulphate in reducing the duration and severity of cold symptoms.
- Mechanisms of symptoms of the common cold and influenzaRon Eccles
Common Cold Centre, Cardiff University, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US
Br J Hosp Med (Lond) 68:71-5. 2007
- Echinacea for prevention of the common cold: an illustrative overview of how information from different systematic reviews is summarised on the internetAnna Hart
School of Public Health and Clinical Sciences, University of Central Lancashire, Harrington Building, Adelphi Street, Preston, Lancashire, PR1 2HE, UK
Prev Med 49:78-82. 2009..Our study objectives were to illustrate how selection criteria for trials in each of the reviews could lead to different conclusions, and to classify the ways in which webpage authors use the reviews to construct advice about echinacea...
- Zinc lozenges as cure for the common cold--a review and hypothesisGeorge A Eby
Director of Research, George Eby Research Institute, 14909 C Fitzhugh Road, Austin, TX 78736, USA
Med Hypotheses 74:482-92. 2010..the iZn hypothesis, lozenge iZn and total daily iZn in trials were found highly correlated with reductions in common cold durations with statistical significance for mean duration (P<0.001) and median duration (P<0...
- Vitamin C and acute respiratory infectionsH Hemilä
Department of Public Health, University of Helsinki, Finland
Int J Tuberc Lung Dis 3:756-61. 1999So far over 60 studies have examined the effects of vitamin C on the common cold. No effect on common cold incidence was observed in the six largest studies, indicating that vitamin C has no preventive effects in normally nourished ..
- Sleep habits and susceptibility to the common coldSheldon Cohen
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Arch Intern Med 169:62-7. 2009Sleep quality is thought to be an important predictor of immunity and, in turn, susceptibility to the common cold. This article examines whether sleep duration and efficiency in the weeks preceding viral exposure are associated with cold ..
- Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infectionJ E Gern
Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin 53792 4108, USA
Am J Respir Crit Care Med 162:2226-31. 2000..cell type 1 (Th1)- and Th2-like cytokines induced by RV infection may help determine the clinical outcome of common cold infections, raising the possibility that the individual subject's immune response, rather than atopic status ..
- The Wisconsin Upper Respiratory Symptom Survey is responsive, reliable, and validBruce Barrett
Department of Family Medicine, University of Wisconsin Medical School, Madison, 53715, USA
J Clin Epidemiol 58:609-17. 2005..To assess reliability, responsiveness, importance to patients, and convergent validity for the Wisconsin Upper Respiratory Symptom Survey (WURSS-44) and to develop a short-form WURSS...
- Prevalence of viral respiratory tract infections in children with asthmaNino Khetsuriani
Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
J Allergy Clin Immunol 119:314-21. 2007..Previous studies support a strong association between viral respiratory tract infections and asthma exacerbations. The effect of newly discovered viruses on asthma control is less well defined...
- Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysisSachin A Shah
University of Connecticut School of Pharmacy, Storrs, CT, USA
Lancet Infect Dis 7:473-80. 2007..commonly used herbal products, but controversy exists about its benefit in the prevention and treatment of the common cold. Thus, we did a meta-analysis evaluating the effect of echinacea on the incidence and duration of the common ..
- Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trialSteven H Yale
Department of Internal Medicine, Marshfield Clinic, and the Biostatistics and Bioinformatics Core, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
Arch Intern Med 164:1237-41. 2004..We sought to determine the efficacy of a standardized preparation of E purpurea in reducing symptom severity and duration of the common cold.
- Pregnancy complications and delivery outcomes of pregnant women with common coldFerenc Banhidy
Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
Cent Eur J Public Health 14:10-4. 2006To study the association between common cold during pregnancy and pregnancy complications and delivery outcomes: gestational age/birth weight, in addition preterm birth and low birthweight.
- Cough and the common coldF J Curley
Division of Pulmonary Medicine, University of Massachusetts Medical School, Worcester 01655
Am Rev Respir Dis 138:305-11. 1988To determine whether the cough of the common cold arises from upper respiratory stimuli and whether antihistamine-decongestant therapy is an effective treatment for this cough, we prospectively evaluated volunteers with uncomplicated ..
- Efficacy of Echinacea purpurea in patients with a common cold. A placebo-controlled, randomised, double-blind clinical trialB Schulten
Company Medical Service, Madaus AG, Cologne, Germany
Arzneimittelforschung 51:563-8. 2001..Echinaceae purpureae herba (Echinacin, EC31J0) has shown promising results in the relief of common cold symptoms and the time taken to improvement compared to placebo...
- Nitric oxide and the common coldDavid Proud
Respiratory Research Group and Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
Curr Opin Allergy Clin Immunol 5:37-42. 2005The common cold is a clinical syndrome triggered by a variety of viral pathogens, but rhinoviruses are the most frequent cause...
- Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trialV Goel
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada
J Clin Pharm Ther 29:75-83. 2004..chosen most commonly by consumers with the expectation that it will reduce the severity and duration of the common cold. However, the results from a limited number of clinical trials for this application have thus far been ..
- Vitamin C, vitamin E, and beta-carotene in relation to common cold incidence in male smokersHarri Hemilä
Department of Public Health, Universityof Helsinki, Finland
Epidemiology 13:32-7. 2002..E, and beta-carotene, as well as long-term vitamin E and beta-carotene supplementation, on the incidence of common cold episodes...
- Types of stressors that increase susceptibility to the common cold in healthy adultsS Cohen
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Health Psychol 17:214-23. 1998..They were then inoculated with common cold viruses and monitored for the onset of disease...
- Using benefit harm tradeoffs to estimate sufficiently important difference: the case of the common coldBruce Barrett
Department of Family Medicine, University of Wisconsin Medical School, Madison, WI 53715, USA
Med Decis Making 25:47-55. 2005..Little is known about patient preferences regarding benefits and harms of common cold treatments.
- Dynamics of stress-related decrease of salivary immunoglobulin A (sIgA): relationship to symptoms of the common cold and studying behaviorR Deinzer
Institute for Medical Psychology, Heinrich Heine University of Dusseldorf, Germany
Behav Med 23:161-9. 1998..However, no relationship between sIgA and URT symptoms was observed, nor did students who took academic examinations differ from untested controls in symptom rates...
- Mechanisms and Enviromental Determinants of Rhinovirus Illness SeverityJames E Gern; Fiscal Year: 2013..RELEVANCE: Rhinoviruses, originally known as "common cold viruses", also cause lower respiratory illnesses such as childhood wheezing, influenza-like illness, and ..
- Clinical Impact of Human Coronaviruses and Viral DiversityGeoffrey J Gorse; Fiscal Year: 2012..The common cold, but also more severe illnesses involving the respiratory tract may result, including those similar to ..
- Mechanisms of viral proteases in coronavirus replication and pathogenesisAndrew D Mesecar; Fiscal Year: 2013..positive strand RNA viruses which cause a range of illness, from relatively mild respiratory disease (croup and common cold like symptoms due to HCoV- NL63, 229e or OC43) to severe acute respiratory syndrome (SARS) outbreaks in humans...
- Systemic Application for Injury Site Specific Delivery via Neutrophils to Treat BXUDONG J LI; Fiscal Year: 2013..problem and is the second most common reason that Americans go to see their doctor, second only to the most common cold and the flu...
- Enterovirus Vectors with Respiratory Tropism for Cancer ImmunotherapyMatthias Gromeier; Fiscal Year: 2010..We established a rodent model for the common cold in hICAM-1 transgenic mice, which exhibit modest virus replication in the respiratory tract and mild airway ..
- Role of TLR4 in Coronavirus InfectionSteven M Varga; Fiscal Year: 2010..HCoVs) are positive-stranded RNA viruses that are estimated to account for approximately 30% of cases of the common cold. The emergence of a novel HCoV as the etiologic agent of severe acute respiratory syndrome (SARS) demonstrated ..
- Development of the Cotton Rat Model of Rhinovirus Infection and DiseaseJORGE C BLANCO; Fiscal Year: 2013..If successful, the proposed research will result in a valuable experimental resource to test vaccines and therapeutics against the "common cold".
- Chronic Rhinosinusitis Integrative Studies Program (CRISP)Robert P Schleimer; Fiscal Year: 2013..are diagnosed with allergic rhinitis or episodes of ARS (symptoms for 7d to 4wk, to eliminate patients with the common cold);some of these patients progress to CRS with symptoms present for at least 12 weeks;many patients with CRS have ..
- Viral Protein Determinants of Coronavirus Replication FidelityEverett Clinton Smith; Fiscal Year: 2013..a family of positive-stranded RNA viruses that cause respiratory disease in humans ranging in severity from the common cold to severe acute respiratory syndrome (SARS)...
- Social Ties and Health: Aggregating Data from Five Viral-Challenge TrialsSheldon A Cohen; Fiscal Year: 2013..studies (9 different viruses) focused on examining the roles of psychosocial factors in susceptibility to the common cold. In these unique studies, hypothesized predictor and mediating variables were assessed in healthy adults aged ..
- Innate Immunity in Otitis Media PathogenesisDavid J Lim; Fiscal Year: 2013DESCRIPTION (provided by applicant): Following the common cold, otitis media (OM), or inflammation of the middle ear, is the most frequent illness resulting in visits to physicians and the most common cause of hearing impairment and ..
- Environmental Factors in Cognition and Neurobiology of Early Onset SchizophreniaKonasale M Prasad; Fiscal Year: 2013..HSV1 is a double stranded DNA virus that causes common cold sores and requires lodging in the nervous system for its life cycle...
- Towards a Vaccine for the Common ColdTHOMAS JAMES SMITH; Fiscal Year: 2010..this highly diverse family of viruses and allow for a single, peptide-based vaccine that could ameliorate the common cold. Indeed, our preliminary evidence suggests that antiserum to such peptides does have pan-serotypic neutralizing ..
- Assembly of Picornaviral Replication ComplexesOlve Peersen; Fiscal Year: 2009..the heart disease causing coxsackie B3 virus, rhinoviruses that cause more than half the occurrences of the common cold, and the paralyzing poliovirus...
- PICORNAVIRUS MOLECULAR BIOLOGYEckard Wimmer; Fiscal Year: 2013..These infections lead to a variety of diseases ranging from the mild (common cold) to the serious (poliomyelitis)...
- Assembly of Picornaviral Replication ComplexesOLVE BREIEN PEERSEN; Fiscal Year: 2013..the heart disease causing coxsackie B3 virus, rhinoviruses that cause more than half the occurrences of the common cold, and the paralyzing poliovirus...
- PPG: SARS-CoV-host cell interactions and vaccine developmentStanley Perlman; Fiscal Year: 2013..will also investigate the role of ACE2 by comparing cells and mice infected with SARS-CoV and HCoV-NL63, a common cold virus that also uses ACE2 to enter cells but does not cause severe disease...
- Targeting Oral Biofilms with 2-Aminoimidazole/Triazole ConjugatesEva Garland; Fiscal Year: 2010..Dental caries, or tooth decay, affects hundreds of millions of people each year, and is second only to the common cold in its prevalence world-wide...
- Flow-enhanced characterization of drug-resistant virusesJohn Yin; Fiscal Year: 2010..AIDS), influenza, hepatitis, cancer, severe acute respiratory syndrome (SARS), hemorrhagic fever and the common cold. Quantitative assessments of virus infectivity are important in the clinic to test the performance of anti-..
- Developing ICAM-1 for rhinovirus therapeuticsMoonsoo M Jin; Fiscal Year: 2010Human rhinoviruses (HRV) are the major causative agent of the common cold and the most common acute infectious illness in humans...
- Metabolomics of the Virus-host Cell InteractionJoshua D Rabinowitz; Fiscal Year: 2010..Relevance: Viruses cause diseases ranging from the common cold to influenza to AIDS...
- Innovative Tools for In Vivo Computational Prediction of Lumbar StressesRICHARD DAVID KOMISTEK; Fiscal Year: 2010..medical problem in the United States, and the second most common reason for doctor visits behind the common cold. Lower back pain is the leading cause of disability among people ages 19-45 and is the leading cause of missed ..
- Effect of Rhinovirus on airway epithelial reciprocal pathways influence NK cells.Jonathan Koff; Fiscal Year: 2013..RELEVANCE (See instructions): In addition to causing the common cold, Rhinovirus is responsible for causing exacerbations of chronic airway diseases (e.g. asthma)...
- Rates of rhinovirus species in adults and children with acute respiratory illnessEVA KATHRYN MILLER; Fiscal Year: 2013DESCRIPTION (provided by applicant): Human rhinoviruses (HRV) are the leading cause of the common cold and more recently have been implicated in lower respiratory illness, in infants and children...
- Data-driven Computational Modeling of the Growth and Spread of VirusesJohn Yin; Fiscal Year: 2010..Viruses also cause many human diseases including, for example, AIDS, influenza, cancer, SARS, and the common cold. Moreover, natural and engineered viruses have potential applications as vaccines and anti-cancer therapeutics...
- Phosphine-Catalyzed Annulations and Their ApplicationsOhyun Kwon; Fiscal Year: 2010..The targets chosen are highly relevant to national public health, specifically the treatment of the common cold, hypertension, amoebic dysentery, malaria, arrhythmia, and cancer...
- DNA Analysis in Multi-Phase Microfabricated DevicesMark A Burns; Fiscal Year: 2010..We will target pathogens associated with acute (the common cold) and chronic (multiple-species bacterial) respiratory infections for our main applications...
- Investigation and Development of New Therapeutic Avenues for SclerodermaEMANUAL M MAVERAKIS; Fiscal Year: 2011..Public Health Relevance: Normally the immune system functions to fight off infections such as the common cold. In patients with autoimmunity the cells of the immune system damage the tissues and organs of a patient...
- MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATIONJames Bert Flanegan; Fiscal Year: 2010..with these viruses include paralytic poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Post-polio syndrome is also an important clinical manisfestation that occurrs in patients 30-40 years after ..
- Evolution of Virus-Host InteractionsJohn Yin; Fiscal Year: 2013..to human health based on their ability to cause diseases such as AIDS, influenza, hepatitis, cancer and the common cold. Basic research has revealed much about the molecular details of processes that are essential for viruses to ..
- CONFERENCE ON POSITIVE-STRAND RNA VIRUSESMARGO BRINTON; Fiscal Year: 1992..from positive-strand RNA virus infections includes encephalitis, poliomyelitis, heart disease, hepatitis, the common cold, gastroenteritis, hemorrhagic fever, and birth defects...
- A Data-mining Approach to CAM Medication ReconciliationWILLIAM Z TAN; Fiscal Year: 2012..Phase I activities will generate a prototype for evaluating one frequently encountered condition: the common cold. This prototype will provide a solid foundation for system expansion, in Phase II, to cover a broad range of ..
- Transgenic Mouse Model for the Common ColdMatthias Gromeier; Fiscal Year: 2009..Despite the generally benign course of the common cold caused by picornaviruses, it is the main culprit for acute exacerbation of serious respiratory system disorders,..
- CONFERENCE ON POSITIVE-STRAND RNA VIRUSESMARGO BRINTON; Fiscal Year: 2001..Human encephalitis, poliomyelitis, heart disease, hepatitis, the common cold, gastroenteritis, haemorrhagic fever, eye infections, and birth defects are caused by positive-strand RNA ..
- STRUCTURE OF POLIOVIRUS/ANTIVIRAL DRUG COMPLEXESJAMES HOGLE; Fiscal Year: 1991..These drugs are of considerable medical and economic significance for prophylaxis of rhinovirus induced common cold (which account for 80% of the colds in the United States) and for early intervention in poliomyelitis and ..
- BIOELASTIC MATERIAL TO PREVENT POST-LAMINECTOMY ADHESIONJie Xu; Fiscal Year: 2001..APPLICATION: Low back pain, for which intervertebral disc pathology is the major cause, is second only to the common cold for work absenteeism in the United States; it is reported to result in more productivity loss than any other ..
- INHIBITION OF NUCLEO-CYTOPLASMIC TRANSPORT BY RHINOVIRUSKURT GUSTIN; Fiscal Year: 2005The most prevalent form of viral respiratory illness is the common cold, which is itself most often associated with infection by rhinovirus...
- A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CAREJames Quinn; Fiscal Year: 2004DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
- Exhaled Biomarkers During Treatment of RhinovirusJohn Hunt; Fiscal Year: 2004..The mechanisms by which this common cold virus caused alteration in airway physiology are not well characterized in part because of the difficulty of ..
- TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSESAsim Dasgupta; Fiscal Year: 2003..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
- BIOELASTIC MATERIALS FOR INTERVERTEBRAL DISC RESTORATIONAsima Pattanaik; Fiscal Year: 1999..APPLICATIONS: Low back pain, for which intervertebral disc pathology is the major cause, is second only to the common cold for work absenteeism in the United States; it is reported to result in more productivity loss than any other ..
- STRUCTURE AND FUNCTION OF THE POLIOVIRUS RNA GENOMEPeter Sarnow; Fiscal Year: 1991..knowledge of the structure and function of the poliovirus genome might be applicable to the genomes of other medically important RNA viruses such as foot and mouth disease virus and human rhinovirus, responsible for the common cold.
- Optimization of Codon-Pair Usage to Maximize Protein Expression in PlantsKEITH WYCOFF; Fiscal Year: 2007..intoxication by Botulinum Neurotoxin A (BoNT/A), the most potent toxin known and a bio-terror agent, the common cold, dental caries and intoxication by Anthrax toxin, also a bio-terror agent...
- RECENT ADVANCES IN OTITIS MEDIA--RESEARCH CONFERENCEThomas Demaria; Fiscal Year: 1991..OM is second only to the common cold as the most common children's disease in the U.S...
- RECENT ADVANCES IN OTITIS MEDIA--RESEARCH CONFERENCEDavid Lim; Fiscal Year: 1999..Otitis Media is second only to the common cold as the most common children's disease in the United States...
- CORONAVIRUS-RECEPTOR INTERACTIONSKathryn Holmes; Fiscal Year: 2003..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
- System to Detect Severe Respiratory Illness by Vocalization Analysis of CoughSuzanne Smith; Fiscal Year: 2009..as tuberculosis, pertussis and influenza from those with coughs related to less serious conditions such as the common cold. PUBLIC HEALTH RELEVANCE: We propose to use vocalization analysis software to characterize coughs...
- Novel Cap Analogs and Interactions with Target ProteinsROBERT RHOADS; Fiscal Year: 2005..They also have relevance for diseases caused by picornaviruses such as poliovirus (polio), rhinovirus (the common cold) and Coxsackievirus (heart failure), since picomaviruses shut down cap-dependent translation by proteolytically ..
- Viral-Driven Mediators of Chronic Lung Allograft DysfunctionRichard Pierce; Fiscal Year: 2009..In lay terms, we have previously shown that the common cold, or a respiratory viral infection, is associated with chronic lung disease in people that have had a lung ..
- Temperature-dependent, Intermediate Particles from the Entry of Picornaviruses inDavid Belnap; Fiscal Year: 2009..Understanding the entry process of picornaviruses will give a fuller mechanistic picture of how these and other viruses cause disease and may give insights into anti-viral therapies. ..
- Nitration immunologyJohn Hunt; Fiscal Year: 2005..and compare these conditions to those found in the airways during inflammation such as occurs with the common cold. Expanding upon supportive preliminary data, we will concurrently investigate the potential of nitrated ..
- Recent Advancees in Otitis Media: Research ConferenceDavid Lim; Fiscal Year: 2003Following the common cold, otitis media (OM), or inflammation of the middle ear, is the most frequent illness resulting in visits to physicians and the most common cause of hearing impairment in children...
- Amplicon Plus for High-Level Expression of Therapeutic Proteins in PlantsKEITH WYCOFF; Fiscal Year: 2005..a recombinant therapeutic protein that is being developed by Planet Biotechnology for prevention of the common cold. The overall plan for the Phase I research is to design and construct amplicon-plus transgenic plants to ..
- Placebo: Physician or Pill? RCT in a commom cold modelBruce Barrett; Fiscal Year: 2006..The nature and magnitude of placebo effects, however, is very poorly understood. Specific aims. Using a common cold model, this study will assess two kinds of "placebo effects": 1) the effect of receiving blinded placebo, ..
- Structural Studies of Virus Assembly & DNA PackagingMARC MORAIS; Fiscal Year: 2004..Viral infection is a significant cause of human illness, ranging from relatively minor ailments such as the common cold to life threatening diseases such as cancer and AIDS...
- Data-driven Computational Modeling of the Growth and Spread of VirusesJohn Yin; Fiscal Year: 2007..Viruses also cause many human diseases including, for example, AIDS, influenza, cancer, SARS, and the common cold. Moreover, natural and engineered viruses have potential applications as vaccines and anti-cancer therapeutics...
- Tetravalent Humanized Anti-ICAM for Rhinovirus InfectionFang Fang; Fiscal Year: 2001The common cold is the most prevalent disease affecting humans, and 70 percent of cases are caused by rhinoviruses (HRV)...
- Rhinovirus accelerates wound repair via surface signaling EGFR activationJonathan Koff; Fiscal Year: 2007..RV infection has clinical importance because the virus is the predominant cause of the common cold and causes exacerbations of asthma and COPD...
- Human Coronaviruses as Multigene Mucosal Vaccine Vectors for HIVAmy Sims; Fiscal Year: 2009..The common cold human coronavirus (HCoV) OC43 is attractive as a vaccine vector for HIV, and recent breakthroughs in ..
- LBP with Radiculopathy: An Inflammatory ResponseJOYCE DELEO; Fiscal Year: 2005Low back pain is a major clinical problem second only to the common cold in its financial and symptomatic impact on human suffering...
- Affinity Enhancement of a Humanized Anti-ICAM AntibodyFang Fang; Fiscal Year: 2001The common cold is a benign disease that also causes ear infections in children and is a leading cause of "attacks" in asthmatic patients...
- Novel Treatment for Parkinson's DiseaseDale Christensen; Fiscal Year: 2007..PD treatment is currently more like a common cold, with drugs that alleviate symptoms but do not address the underlying cause of the disease...