common cold

Summary

Summary: A catarrhal disorder of the upper respiratory tract, which may be viral, a mixed infection, or an allergic reaction. It is marked by acute coryza, slight rise in temperature, chilly sensations, and general indisposition. (Dorland, 27th ed)

Top Publications

  1. doi Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate
    Ananda S Prasad
    Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Infect Dis 197:795-802. 2008
  2. ncbi The common cold
    Terho Heikkinen
    Department of Paediatrics, Turku University Hospital, Turku, Finland
    Lancet 361:51-9. 2003
  3. pmc Viruses and bacteria in the etiology of the common cold
    M J Mäkelä
    Department of Pediatrics, University of Turku, Finland
    J Clin Microbiol 36:539-42. 1998
  4. ncbi Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians
    R Gonzales
    Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    JAMA 278:901-4. 1997
  5. pmc Practitioner empathy and the duration of the common cold
    David P Rakel
    School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA
    Fam Med 41:494-501. 2009
  6. ncbi Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial
    Michael de Vrese
    Institute of Physiology and Biochemistry of Nutrition, Federal Research Centre of Nutrition and Food, Hermann Weigmann Strasse 1, D 24103 Kiel, Germany
    Vaccine 24:6670-4. 2006
  7. ncbi Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study
    Jonathan M Corne
    University Medicine, Southampton General Hospital, Southampton, UK
    Lancet 359:831-4. 2002
  8. pmc Consumer attitudes and use of antibiotics
    Jodi Vanden Eng
    Connecticut Emerging Infections Program, New Haven 06510, USA
    Emerg Infect Dis 9:1128-35. 2003
  9. ncbi Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common cold
    Hong Jun Cho
    Department of Family Medicine, University of Ulsan College of Medicine, Songpa P O Box 145, Seoul 138 736, South Korea
    Soc Sci Med 58:623-9. 2004
  10. ncbi Misconceptions about colds and predictors of health service utilization
    Grace M Lee
    Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 111:231-6. 2003

Detail Information

Publications234 found, 100 shown here

  1. doi Duration and severity of symptoms and levels of plasma interleukin-1 receptor antagonist, soluble tumor necrosis factor receptor, and adhesion molecules in patients with common cold treated with zinc acetate
    Ananda S Prasad
    Department of Internal Medicine, Wayne State University School of Medicine, Detroit, MI 48201, USA
    J Infect Dis 197:795-802. 2008
    Zinc lozenges have been used for treatment of the common cold; however, the results remain controversial.
  2. ncbi The common cold
    Terho Heikkinen
    Department of Paediatrics, Turku University Hospital, Turku, Finland
    Lancet 361:51-9. 2003
    Despite great advances in medicine, the common cold continues to be a great burden on society in terms of human suffering and economic losses. Of the several viruses that cause the disease, the role of rhinoviruses is most prominent...
  3. pmc Viruses and bacteria in the etiology of the common cold
    M J Mäkelä
    Department of Pediatrics, University of Turku, Finland
    J Clin Microbiol 36:539-42. 1998
    ..The results show that although approximately 50% of episodes of the common cold were caused by rhinoviruses, the etiology can vary depending on the epidemiological situation with regard to ..
  4. ncbi Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians
    R Gonzales
    Division of General Internal Medicine, University of Colorado Health Sciences Center, Denver 80262, USA
    JAMA 278:901-4. 1997
    ..How frequently antibiotics are prescribed for these conditions and for and by whom is not known...
  5. pmc Practitioner empathy and the duration of the common cold
    David P Rakel
    School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA
    Fam Med 41:494-501. 2009
    This study's objective was to assess the relationship of empathy in medical office visits to subsequent outcomes of the common cold.
  6. ncbi Probiotic bacteria reduced duration and severity but not the incidence of common cold episodes in a double blind, randomized, controlled trial
    Michael de Vrese
    Institute of Physiology and Biochemistry of Nutrition, Federal Research Centre of Nutrition and Food, Hermann Weigmann Strasse 1, D 24103 Kiel, Germany
    Vaccine 24:6670-4. 2006
    To investigate the effect of long-term consumption of probiotic bacteria on viral respiratory tract infections (common cold, influenza), a randomized, double blind, controlled intervention study was performed during two winter/spring ..
  7. ncbi Frequency, severity, and duration of rhinovirus infections in asthmatic and non-asthmatic individuals: a longitudinal cohort study
    Jonathan M Corne
    University Medicine, Southampton General Hospital, Southampton, UK
    Lancet 359:831-4. 2002
    ..Rhinovirus infections cause exacerbations of asthma. We postulated that people with asthma are more susceptible to rhinovirus infection than people without the disease and compared the susceptibility of these groups...
  8. pmc Consumer attitudes and use of antibiotics
    Jodi Vanden Eng
    Connecticut Emerging Infections Program, New Haven 06510, USA
    Emerg Infect Dis 9:1128-35. 2003
    ..National educational efforts are needed to address these issues if patient demand for antibiotics is to be reduced...
  9. ncbi Knowledge and beliefs of primary care physicians, pharmacists, and parents on antibiotic use for the pediatric common cold
    Hong Jun Cho
    Department of Family Medicine, University of Ulsan College of Medicine, Songpa P O Box 145, Seoul 138 736, South Korea
    Soc Sci Med 58:623-9. 2004
    ..practitioners and pediatricians), pharmacists, and parents regarding the use of antibiotics for the pediatric common cold, using a self-administered questionnaire for physicians and pharmacists and a telephone interview for parents...
  10. ncbi Misconceptions about colds and predictors of health service utilization
    Grace M Lee
    Division of Infectious Diseases, Children s Hospital, Boston, Massachusetts 02115, USA
    Pediatrics 111:231-6. 2003
    ..The objective of this study was to determine predictors of reported ED use and ambulatory care use for colds among families with young children...
  11. ncbi Treatment of the common cold
    Madeline Simasek
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Am Fam Physician 75:515-20. 2007
    The common cold is a viral illness that affects persons of all ages, prompting frequent use of over-the-counter and prescription medications and alternative remedies. Treatment focuses on relieving symptoms (e.g...
  12. ncbi Rhinovirus infection increases 5-lipoxygenase and cyclooxygenase-2 in bronchial biopsy specimens from nonatopic subjects
    Michelle L Seymour
    Division of Respiratory Cell and Molecular Biology, University of Southampton School of Medicine, Southampton, United Kingdom
    J Infect Dis 185:540-4. 2002
    ..13). Cold symptom scores correlated with bronchial immunostaining for FLAP (rho = 0.93; P =.001). In normal subjects, rhinovirus colds induce bronchial inflammation with markedly enhanced expression of 5-LO pathway proteins and COX-2...
  13. pmc Nasal inflammation induced by a common cold: comparison between controls and patients with nasal polyposis under topical steroid therapy
    C Dassonville
    Laboratory of Public Health and Environment, Faculty of Pharmacy, University Paris V, Paris
    Acta Otorhinolaryngol Ital 27:78-82. 2007
    The evolution of nasal inflammation during a common cold in patients with nasal polyposis under topical steroid treatment is not clearly defined in the literature...
  14. ncbi Inflammatory changes during the 'common cold' are associated with platelet activation and increased reactivity of platelets to agonists
    Rolf P Kreutz
    Sinai Center for Thrombosis Research, Baltimore, Maryland 21215, USA
    Blood Coagul Fibrinolysis 18:713-8. 2007
    ..We hypothesized that changes in platelet activation and reactivity and inflammation occur during the 'common cold'. Previously healthy individuals with viral upper respiratory tract infections were studied (n = 18)...
  15. ncbi Transmission of viral respiratory infections in the home
    D A Goldmann
    Department of Medicine Children s Hospital, Boston, MA 02115, USA
    Pediatr Infect Dis J 19:S97-102. 2000
    ..study, from the plains of Salisbury, to the hills of Virginia, to the collegiate environment of Madison, WI, the precise routes rhinovirus takes to inflict the misery of the common cold on a susceptible population remain controversial.
  16. pmc Sleep habits and susceptibility to the common cold
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Arch Intern Med 169:62-7. 2009
    Sleep quality is thought to be an important predictor of immunity and, in turn, susceptibility to the common cold. This article examines whether sleep duration and efficiency in the weeks preceding viral exposure are associated with cold ..
  17. ncbi Rhinovirus-induced airway inflammation in asthma: effect of treatment with inhaled corticosteroids before and during experimental infection
    K Grunberg
    Department of Pulmonology, Department of Medical Decision Making, Leiden University Medical Center LUMC, Leiden, The Netherlands
    Am J Respir Crit Care Med 164:1816-22. 2001
    ..The latter finding is in keeping with the limited protection of inhaled corticosteroids against acute asthma exacerbations...
  18. ncbi Psychological stress and susceptibility to the common cold
    S Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213
    N Engl J Med 325:606-12. 1991
    ..To investigate this issue, we prospectively studied the relation between psychological stress and the frequency of documented clinical colds among subjects intentionally exposed to respiratory viruses...
  19. pmc Iota-Carrageenan is a potent inhibitor of rhinovirus infection
    Andreas Grassauer
    Marinomed Biotechnologie GmbH, Veterinaerplatz 1 HA, A 1210 Vienna, Austria
    Virol J 5:107. 2008
    Human rhinoviruses (HRVs) are the predominant cause of common cold. In addition, HRVs are implicated in the worsening of COPD and asthma, as well as the loss of lung transplants...
  20. pmc Weekly monitoring of children with asthma for infections and illness during common cold seasons
    Jaime P Olenec
    Department of Pediatrics, University of Wisconsin, Madison, WI 53792 4108, USA
    J Allergy Clin Immunol 125:1001-1006.e1. 2010
    ..Exacerbations of childhood asthma and rhinovirus infections both peak during the spring and fall, suggesting that viral infections are major contributors to seasonal asthma morbidity...
  21. ncbi Epidemiological relationships between the common cold and exacerbation frequency in COPD
    J R Hurst
    Academic Unit of Respiratory Medicine, Royal Free and University College Medical School, Hampstead, London, NW3 2QG, UK
    Eur Respir J 26:846-52. 2005
    ..Exacerbation frequency in chronic obstructive pulmonary disease is associated with an increased frequency of acquiring the common cold, rather than an increased propensity to exacerbation once a cold has been acquired.
  22. ncbi Relations among questionnaire and laboratory measures of rhinovirus infection
    B Barrett
    University of Wisconsin Medical School, 777 S Mills, Madison, WI 53715, USA
    Eur Respir J 28:358-63. 2006
    ..The inclusion of functional and quality-of-life items in the Wisconsin Upper Respiratory Symptom Survey does not significantly decrease the strength of association with laboratory-assessed biomarkers...
  23. ncbi Rhinovirus infections: more than a common cold
    Marc B Hershenson
    Am J Respir Crit Care Med 174:1284-5. 2006
  24. pmc A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes
    Mariana Mesel-Lemoine
    Unité de Génomique Virale et Vaccination, Department of Virology, Institut Pasteur, CNRS URA 3015, Paris, France
    J Virol 86:7577-87. 2012
    ....
  25. pmc Complementary and alternative medicine for prevention and treatment of the common cold
    Richard Nahas
    Seekers Centre for Integrative Medicine, Ottawa, ON
    Can Fam Physician 57:31-6. 2011
    To review the evidence supporting complementary and alternative medicine approaches to treatment and prevention of the common cold in adults.
  26. pmc Placebo effects and the common cold: a randomized controlled trial
    Bruce Barrett
    University of Wisconsin, Madison, Madison, Wisconsin, USA
    Ann Fam Med 9:312-22. 2011
    We wanted to determine whether the severity and duration of illness caused by the common cold are influenced by randomized assignment to open-label pills, compared with conventional double-blind allocation to active and placebo pills, ..
  27. pmc Predicting worsening asthma control following the common cold
    M J Walter
    Division of Pulmonary and Critical Care Medicine, Campus Box 8052, 660 South Euclid Ave, St Louis, MO 63110, USA
    Eur Respir J 32:1548-54. 2008
    The asthmatic response to the common cold is highly variable, and early characteristics that predict worsening of asthma control following a cold have not been identified...
  28. doi Herbs and other dietary supplements: current regulations and recommendations for use to maintain health in the management of the common cold or other related infectious respiratory illnesses
    Angelo Mathes
    Consultation Angelo Inc, Town of Mount Royal, QC, Canada
    J Pharm Pract 23:117-27. 2010
    ..The common cold is an important illness due to its recurring nature, the number of people it afflicts, and its economic impact ..
  29. ncbi Safety and efficacy of over-the-counter cough and cold medicines for use in children
    Zdravko P Vassilev
    Epidemiology, Covance Periapproval Services, 555 North Lane, Suite 6000, Conshohocken, PA, USA
    Expert Opin Drug Saf 9:233-42. 2010
    ....
  30. ncbi Dynamics of human respiratory virus-specific CD8+ T cell responses in blood and airways during episodes of common cold
    Jojanneke Heidema
    Division of Paediatrics, Wilhelmina Children s Hospital, Utrecht, The Netherlands
    J Immunol 181:5551-9. 2008
    ..Taken together, these results showed a significant systemic T cell response during relatively mild secondary infections and extensive dynamics of virus-specific and nonspecific Ag-experienced T cells...
  31. ncbi Safety and efficacy evaluation of pleconaril for treatment of the common cold
    Russell Fleischer
    Clin Infect Dis 37:1722. 2003
  32. ncbi Treatment of the common cold with echinacea: a structured review
    Thomas J Caruso
    Stanford University School of Medicine, Stanford, CA, USA
    Clin Infect Dis 40:807-10. 2005
    Echinacea is a herbal preparation that is frequently used to treat the common cold. Spending on echinacea in the United States has risen to >300 million dollars annually.
  33. ncbi Capturing the onset of the common cold and its effects on iron absorption
    M Hoppe
    Department of Clinical Nutrition, Institute of Internal Medicine, The Sahlgrenska Academy at Goteborg University, S 405 30 Gothenburg, Sweden
    Eur J Clin Nutr 61:1032-4. 2007
    ..However, to our best knowledge there are no previous published reports on the outbreak of a common cold and its initial effect on iron kinetics. The objective of this case report is to describe such an observation...
  34. ncbi Efficacy and safety of over-the-counter analgesics in the treatment of common cold and flu
    R Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    J Clin Pharm Ther 31:309-19. 2006
    b>Common cold and flu are the most common human illnesses, and over-the-counter (OTC) analgesics are widely used to treat the pain and fever symptoms...
  35. ncbi Vitamin C for preventing and treating the common cold
    Harri Hemilä
    Department of Public Health, POB 41, University of Helsinki, Helsinki, Finland
    Cochrane Database Syst Rev 1:CD000980. 2013
    Vitamin C (ascorbic acid) for preventing and treating the common cold has been a subject of controversy for 70 years.
  36. ncbi Aircraft cabin air recirculation and symptoms of the common cold
    Jessica Nutik Zitter
    Department of Medicine, University of California, San Francisco, Box 0843, San Francisco, CA 94143 0843, USA
    JAMA 288:483-6. 2002
    ..Whether air recirculation increases the transmission of infectious disease is unknown; some studies have demonstrated higher rates of the common cold among persons working in buildings that recirculate air.
  37. doi Effects of So-cheong-ryong-tang and Yeon-gyo-pae-dok-san on the common cold: randomized, double blind, placebo controlled trial
    Jun Seop Byun
    Department of Internal Medicine, Oriental Medical College of Daejeon University, 96 3 Yongwun dong, Daejeon 300 716, South Korea
    J Ethnopharmacol 133:642-6. 2011
    So-cheong-ryong-tang (SCRT) and Yeon-gyo-pae-dok-san (YPS) extracts are widely used in treatment of the common cold. The purpose of this study is to evaluate the efficacy of SCRT and YPS on the common cold.
  38. ncbi Problems and prospects of developing effective therapy for common cold viruses
    S L Johnston
    University Medicine, Southampton General Hospital, UK
    Trends Microbiol 5:58-63. 1997
    ..These approaches offer new avenues for treating populations at risk and are of particular significance to those with asthma or chronic bronchitis...
  39. ncbi Intake of wine, beer, and spirits and the risk of clinical common cold
    Bahi Takkouche
    Department of Preventive Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain
    Am J Epidemiol 155:853-8. 2002
    To examine whether intakes of wine, beer, spirits, and total alcohol are associated with the risk of common cold, in 1998-1999 the authors analyzed data from a cohort study carried out in a population of 4,272 faculty and staff of five ..
  40. pmc Hydrogen peroxide in breath condensate during a common cold
    R Q Jöbsis
    Department of Paediatrics, Division of Paediatric Respiratory Medicine, Erasmus University Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
    Mediators Inflamm 10:351-4. 2001
    ..Hydrogen peroxide (H2O2) in exhaled air condensate is elevated in inflammatory disorders of the lower respiratory tract. It is unknown whether viral colds contribute to exhaled H2O2...
  41. pmc The incidence, prevalence and burden of OM in unselected children aged 1-8 years followed by weekly otoscopy through the "common cold" season
    Ellen M Mandel
    Department of Otolaryngology, Children s Hospital of Pittsburgh and the University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Pediatr Otorhinolaryngol 72:491-9. 2008
    ..Often overlooked in past studies are the contributions of cold-like illnesses (CLIs) and sampling interval to those estimates...
  42. ncbi Efficacy of a pelargonium sidoides preparation in patients with the common cold: a randomized, double blind, placebo-controlled clinical trial
    Viktor G Lizogub
    Faculty Therapy No 2, National Medical University, Kiev, Ukraine
    Explore (NY) 3:573-84. 2007
    The common cold is a viral infection with symptoms such as sneezing, sore throat, and running nose...
  43. ncbi Respiratory consequences of rhinovirus infection
    Stephen B Greenberg
    Department of Internal Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA
    Arch Intern Med 163:278-84. 2003
    ..By altering the clinical course of picornavirus infections, it may be possible to minimize their potential adverse consequences...
  44. ncbi The prophylactic and therapeutic effectiveness of zinc sulphate on common cold in children
    Zafer Kurugol
    Department of Paediatrics, Faculty of Medicine, Ege University, Izmir, Turkey
    Acta Paediatr 95:1175-81. 2006
    To determine the efficacy of prophylactic administration of zinc sulphate in reducing the occurrence of the common cold in children, and to evaluate the efficacy of zinc sulphate in reducing the duration and severity of cold symptoms.
  45. pmc Willingness to pay for health care services in common cold, retinal detachment, and myocardiac infarction: an internet survey in Japan
    Hideo Yasunaga
    Department of Planning, Information and Management, University of Tokyo Hospital, Tokyo, Japan
    BMC Health Serv Res 6:12. 2006
    ..The objective of this survey is to measure WTP for the treatment of typical acute illnesses and to analyze the factors affecting WTP...
  46. ncbi Mechanisms of symptoms of the common cold and influenza
    Ron Eccles
    Common Cold Centre, Cardiff University, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US
    Br J Hosp Med (Lond) 68:71-5. 2007
  47. ncbi Vitamin C and acute respiratory infections
    H Hemilä
    Department of Public Health, University of Helsinki, Finland
    Int J Tuberc Lung Dis 3:756-61. 1999
    So far over 60 studies have examined the effects of vitamin C on the common cold. No effect on common cold incidence was observed in the six largest studies, indicating that vitamin C has no preventive effects in normally nourished ..
  48. doi Zinc lozenges as cure for the common cold--a review and hypothesis
    George A Eby
    Director of Research, George Eby Research Institute, 14909 C Fitzhugh Road, Austin, TX 78736, USA
    Med Hypotheses 74:482-92. 2010
    ..the iZn hypothesis, lozenge iZn and total daily iZn in trials were found highly correlated with reductions in common cold durations with statistical significance for mean duration (P<0.001) and median duration (P<0...
  49. ncbi Evidence for correlation of objective and subjective measures of nasal airflow in patients with common cold
    J D Clarke
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Clin Otolaryngol 30:35-8. 2005
    ..To utilize posterior rhinomanometry and conductance, as units of measurement, to further investigate the relationship between subjective and objective measures of nasal airflow...
  50. ncbi Visits by adults to family physicians for the common cold
    W J McIsaac
    Mt Sinai Family Medicine Centre, Toronto, Ontario, Canada
    J Fam Pract 47:366-9. 1998
    ..We examined how often a large population of adults visited doctors when they had a cold, the degree to which they engaged in self care, and the characteristics of those seeking care...
  51. ncbi [Cough induction by high-frequency chest percussion in healthy volunteers and patients with common cold]
    P C L Lee
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, Cardiff CF10 3US, UK
    Respir Med 98:771-6. 2004
    ..The aim of this study was to determine if cough can be induced by high-frequency chest percussion in healthy subjects and in patients with acute upper respiratory tract infection (URTI)...
  52. doi Echinacea for preventing and treating the common cold
    Karin Woelkart
    Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl Franzens University, Graz, Austria
    Planta Med 74:633-7. 2008
    Echinacea preparations are widely used for common cold. Many consumers and healthcare professionals are not aware that products available under the term Echinacea may differ in their composition, due to the use of different species, ..
  53. doi Echinacea for prevention of the common cold: an illustrative overview of how information from different systematic reviews is summarised on the internet
    Anna Hart
    School of Public Health and Clinical Sciences, University of Central Lancashire, Harrington Building, Adelphi Street, Preston, Lancashire, PR1 2HE, UK
    Prev Med 49:78-82. 2009
    ..Our study objectives were to illustrate how selection criteria for trials in each of the reviews could lead to different conclusions, and to classify the ways in which webpage authors use the reviews to construct advice about echinacea...
  54. ncbi A clinical trial of hypertonic saline nasal spray in subjects with the common cold or rhinosinusitis
    P Adam
    Riverside University Family Practice Clinic, University of Minnesota Department of Family Practice and Community Health, Minneapolis 55406, USA
    Arch Fam Med 7:39-43. 1998
    To determine whether hypertonic saline nasal spray relieves nasal symptoms and shortens illness duration in patients with the common cold or acute rhinosinusitis.
  55. pmc Echinacea for treating the common cold: a randomized trial
    Bruce Barrett
    Department of Family Medicine, University of Wisconsin, Madison, Wisconsin 53715, USA
    Ann Intern Med 153:769-77. 2010
    Echinacea is widely used to treat the common cold.
  56. ncbi The Wisconsin Upper Respiratory Symptom Survey is responsive, reliable, and valid
    Bruce Barrett
    Department of Family Medicine, University of Wisconsin Medical School, Madison, 53715, USA
    J Clin Epidemiol 58:609-17. 2005
    ..To assess reliability, responsiveness, importance to patients, and convergent validity for the Wisconsin Upper Respiratory Symptom Survey (WURSS-44) and to develop a short-form WURSS...
  57. ncbi Prevalence of viral respiratory tract infections in children with asthma
    Nino Khetsuriani
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    J Allergy Clin Immunol 119:314-21. 2007
    ..Previous studies support a strong association between viral respiratory tract infections and asthma exacerbations. The effect of newly discovered viruses on asthma control is less well defined...
  58. ncbi Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis
    Sachin A Shah
    University of Connecticut School of Pharmacy, Storrs, CT, USA
    Lancet Infect Dis 7:473-80. 2007
    ..commonly used herbal products, but controversy exists about its benefit in the prevention and treatment of the common cold. Thus, we did a meta-analysis evaluating the effect of echinacea on the incidence and duration of the common ..
  59. ncbi Cough and the common cold
    F J Curley
    Division of Pulmonary Medicine, University of Massachusetts Medical School, Worcester 01655
    Am Rev Respir Dis 138:305-11. 1988
    To determine whether the cough of the common cold arises from upper respiratory stimuli and whether antihistamine-decongestant therapy is an effective treatment for this cough, we prospectively evaluated volunteers with uncomplicated ..
  60. ncbi Echinacea purpurea therapy for the treatment of the common cold: a randomized, double-blind, placebo-controlled clinical trial
    Steven H Yale
    Department of Internal Medicine, Marshfield Clinic, and the Biostatistics and Bioinformatics Core, Marshfield Clinic Research Foundation, Marshfield, WI 54449, USA
    Arch Intern Med 164:1237-41. 2004
    ..We sought to determine the efficacy of a standardized preparation of E purpurea in reducing symptom severity and duration of the common cold.
  61. ncbi Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial
    Michael de Vrese
    Institute for Physiology and Biochemistry of Nutrition, Federal Research Centre of Nutrition and Food, Hermann Weigmann Strasse 1, D 24103 Kiel, Germany
    Clin Nutr 24:481-91. 2005
    ..bifidum MF 20/5 (5 x 10(7) cfu/tablet) during at least 3 months influences the severity of symptoms and the incidence and duration of the common cold.
  62. ncbi Pregnancy complications and delivery outcomes of pregnant women with common cold
    Ferenc Banhidy
    Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Budapest, Hungary
    Cent Eur J Public Health 14:10-4. 2006
    To study the association between common cold during pregnancy and pregnancy complications and delivery outcomes: gestational age/birth weight, in addition preterm birth and low birthweight.
  63. ncbi Efficacy of Echinacea purpurea in patients with a common cold. A placebo-controlled, randomised, double-blind clinical trial
    B Schulten
    Company Medical Service, Madaus AG, Cologne, Germany
    Arzneimittelforschung 51:563-8. 2001
    ..Echinaceae purpureae herba (Echinacin, EC31J0) has shown promising results in the relief of common cold symptoms and the time taken to improvement compared to placebo...
  64. ncbi Nitric oxide and the common cold
    David Proud
    Respiratory Research Group and Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
    Curr Opin Allergy Clin Immunol 5:37-42. 2005
    The common cold is a clinical syndrome triggered by a variety of viral pathogens, but rhinoviruses are the most frequent cause...
  65. ncbi Efficacy of a standardized echinacea preparation (Echinilin) for the treatment of the common cold: a randomized, double-blind, placebo-controlled trial
    V Goel
    Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada
    J Clin Pharm Ther 29:75-83. 2004
    ..chosen most commonly by consumers with the expectation that it will reduce the severity and duration of the common cold. However, the results from a limited number of clinical trials for this application have thus far been ..
  66. ncbi Patient beliefs about the characteristics, causes, and care of the common cold: an update
    B L Braun
    Health Research Center, Institute for Research and Education, HealthSystem Minnesota, Minneapolis 55416, USA
    J Fam Pract 49:153-6. 2000
    ..Many people seek medical care for cold symptoms. The cold-related knowledge and beliefs of adults seeking medical care for themselves or their children may not correspond with current medical opinion...
  67. ncbi New considerations in the treatment and prevention of rhinovirus infections
    Ronald B Turner
    University of Virginia School of Medicine, Department of Pediatrics, Charlottesville, VA 22908, USA
    Pediatr Ann 34:53-7. 2005
    ..Although these infections are most closely associated with the common cold, recent studies have established the rhinoviruses as important causes of other upper and lower respiratory ..
  68. pmc Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
    ..Results from these studies in experimental rhinoviral infection support continued investigation of intranasal ruprintrivir in the setting of natural HRV infection...
  69. ncbi Using benefit harm tradeoffs to estimate sufficiently important difference: the case of the common cold
    Bruce Barrett
    Department of Family Medicine, University of Wisconsin Medical School, Madison, WI 53715, USA
    Med Decis Making 25:47-55. 2005
    ..Little is known about patient preferences regarding benefits and harms of common cold treatments.
  70. ncbi Human rhinovirus infection induces airway epithelial cell production of human beta-defensin 2 both in vitro and in vivo
    David Proud
    Respiratory Research Group and Department of Physiology and Biophysics, University of Calgary, Calgary, Alberta, Canada
    J Immunol 172:4637-45. 2004
    ..This represents the first demonstration that HRV infection induces epithelial expression of HBD-2 both in vitro and in vivo, and supports the concept that HBD-2 may play a role in host defense to HRV infection...
  71. ncbi Home-based therapies for the common cold among European American and ethnic minority families: the interface between alternative/complementary and folk medicine
    L M Pachter
    Department of Pediatrics, Saint Francis Hospital and Medical Center, Hartford, Conn 06105, USA
    Arch Pediatr Adolesc Med 152:1083-8. 1998
    ..Also, there has often been a distinction between alternative/ complementary medical practices used by the general population and those used by members of ethnic minority groups and commonly referred to as folk medicine or ethnomedicine...
  72. ncbi Efficacy and safety of single and multiple doses of pseudoephedrine in the treatment of nasal congestion associated with common cold
    Ronald Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff University, United Kingdom
    Am J Rhinol 19:25-31. 2005
    ..taken in tablet or syrup formulations every 4-6 hours for the treatment of nasal congestion associated with common cold and allergy...
  73. pmc Vitamin C for preventing and treating the common cold
    Robert M Douglas
    National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia
    PLoS Med 2:e168; quiz e217. 2005
  74. ncbi Allergic rhinitis and the common cold--high cost to society
    J Hellgren
    Department of Otorhinolaryngology, Head and Neck Surgery, Capio Lundby Hospital, Wieselgrensplatsen 2A, Goteborg, Sweden
    Allergy 65:776-83. 2010
    The common cold and allergic rhinitis constitute a global health problem that affects social life, sleep, school and work performance and is likely to impose a substantial economic burden on society because of absence from work and ..
  75. doi The human rhinovirus: human-pathological impact, mechanisms of antirhinoviral agents, and strategies for their discovery
    Judith M Rollinger
    Institute of Pharmacy Pharmacognosy and Center for Molecular Biosciences Innsbruck, University of Innsbruck, Innrain 52c, A 6020 Innsbruck, Austria
    Med Res Rev 31:42-92. 2011
    As the major etiological agent of the common cold, human rhinoviruses (HRV) cause millions of lost working and school days annually...
  76. ncbi Effectiveness of an antihistamine-decongestant combination for young children with the common cold: a randomized, controlled clinical trial
    N Hutton
    Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Maryland
    J Pediatr 118:125-30. 1991
    ..We conclude that there is no clinically significant improvement in symptoms of upper respiratory tract infection, including no significant placebo effect, in young children for whom an antihistamine-decongestant is prescribed...
  77. doi Rhinovirus transmission within families with children: incidence of symptomatic and asymptomatic infections
    Ville Peltola
    Department of Pediatrics, Turku University Hospital, Turku, Finland
    J Infect Dis 197:382-9. 2008
    ..Rhinoviruses are the most common cause of respiratory tract infections, but the transmission in families has not been studied using sensitive and specific molecular detection methods...
  78. ncbi Comparison of anchor-based and distributional approaches in estimating important difference in common cold
    Bruce Barrett
    Department of Family Medicine, University of Wisconsin Medical School, 777 South Mills, Madison, WI 53715, USA
    Qual Life Res 17:75-85. 2008
    ..Several approaches to minimal important difference (MID) and responsiveness have been developed...
  79. ncbi Rationale and methods for a trial assessing placebo, echinacea, and doctor-patient interaction in the common cold
    Bruce Barrett
    Department of Family Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA
    Explore (NY) 3:561-72. 2007
    ....
  80. ncbi Types of stressors that increase susceptibility to the common cold in healthy adults
    S Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Health Psychol 17:214-23. 1998
    ..They were then inoculated with common cold viruses and monitored for the onset of disease...
  81. ncbi Dynamics of stress-related decrease of salivary immunoglobulin A (sIgA): relationship to symptoms of the common cold and studying behavior
    R Deinzer
    Institute for Medical Psychology, Heinrich Heine University of Dusseldorf, Germany
    Behav Med 23:161-9. 1998
    ..However, no relationship between sIgA and URT symptoms was observed, nor did students who took academic examinations differ from untested controls in symptom rates...
  82. ncbi Population-based case-control study of the common cold during pregnancy and congenital abnormalities
    Nandor Acs
    Second Department of Obstetrics and Gynecology, School of Medicine, Semmelweis University, Budapest, Hungary
    Eur J Epidemiol 21:65-75. 2006
    The common cold is the most frequent maternal disease during pregnancy...
  83. ncbi Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    JAMA 281:1797-804. 1999
    ..Attachment of most rhinovirus subtypes to cells depends on a cellular receptor, the intercellular adhesion molecule 1 (ICAM-1). A recombinant soluble ICAM-1 (tremacamra, formerly BIRR 4) has shown possible efficacy in early studies...
  84. ncbi Understanding the symptoms of the common cold and influenza
    Ron Eccles
    Common Cold Centre, Cardiff School of Biosciences, Cardiff School of Biosciences, Cardiff University, Cardiff, UK
    Lancet Infect Dis 5:718-25. 2005
    The common cold and influenza (flu) are the most common syndromes of infection in human beings...
  85. ncbi Saline nasal irrigation for acute upper respiratory tract infections
    Jessica C Kassel
    School of Population Health, University of Queensland, Brisbane, Australia
    Cochrane Database Syst Rev 3:CD006821. 2010
    BACKGROUND: Acute upper respiratory tract infections (URTIs), including the common cold and rhinosinusitis, are common afflictions that cause discomfort and debilitation, and contribute significantly to workplace absenteeism...
  86. ncbi Variant effect of first- and second-generation antihistamines as clues to their mechanism of action on the sneeze reflex in the common cold
    P S Muether
    Aachen Medical School, Aachen, Germany
    Clin Infect Dis 33:1483-8. 2001
    ..The effectiveness of first-generation antihistamines in blocking sneezing in colds may be due primarily to neuropharmacological manipulation of histaminic and muscarinic receptors in the medulla...
  87. ncbi Productivity losses related to the common cold
    Thomas J Bramley
    J Occup Environ Med 44:822-9. 2002
    ..We conclude that the economic cost of lost productivity due to the common cold approaches $25 billion, of which $16...
  88. ncbi Emotional style and susceptibility to the common cold
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213 3890, USA
    Psychosom Med 65:652-7. 2003
    ..We tested these hypotheses for host resistance to the common cold.
  89. ncbi Combined antiviral-antimediator treatment for the common cold
    Jack M Gwaltney
    Department of Internal Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Infect Dis 186:147-54. 2002
    ..IFN-alpha2b added to the effectiveness of chlorpheniramine and ibuprofen and was well tolerated...
  90. ncbi Effects of rhinovirus infection on histamine and cytokine production by cell lines from human mast cells and basophils
    Masayoshi Hosoda
    Department of Geriatric and Respiratory Medicine, Tohoku University School of Medicine, Sendai, Japan
    J Immunol 169:1482-91. 2002
    ..These findings suggest that RV14 infection may prime the cytokine and histamine production from mast cells and basophils and may cause airway inflammation in asthma...
  91. ncbi Sociability and susceptibility to the common cold
    Sheldon Cohen
    Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Psychol Sci 14:389-95. 2003
    ..They were subsequently exposed to a virus that causes a common cold and monitored to see who developed verifiable illness...
  92. pmc Increase in common cold symptoms and mouth ulcers following smoking cessation
    M Ussher
    Department of Psychology, St George s Hospital Medical School, University of London, UK
    Tob Control 12:86-8. 2003
    To examine changes in reports of common cold symptoms and mouth ulcers following smoking cessation. It was hypothesised that reports of these symptoms would increase on stopping smoking.
  93. ncbi Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection
    J E Gern
    Department of Pediatrics, University of Wisconsin Medical School, Madison, Wisconsin 53792 4108, USA
    Am J Respir Crit Care Med 162:2226-31. 2000
    ..cell type 1 (Th1)- and Th2-like cytokines induced by RV infection may help determine the clinical outcome of common cold infections, raising the possibility that the individual subject's immune response, rather than atopic status ..
  94. ncbi Vitamin C, vitamin E, and beta-carotene in relation to common cold incidence in male smokers
    Harri Hemilä
    Department of Public Health, Universityof Helsinki, Finland
    Epidemiology 13:32-7. 2002
    ..E, and beta-carotene, as well as long-term vitamin E and beta-carotene supplementation, on the incidence of common cold episodes...
  95. ncbi Psychological job demands as a risk factor for common cold in a Dutch working population
    D C Mohren
    Department of Epidemiology, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    J Psychosom Res 50:21-7. 2001
    We investigated the effect of Psychological Job Demands (PJD) on the occurrence of the clinical symptoms of common cold.
  96. ncbi The treatment of rhinovirus infections: progress and potential
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Clinical Sciences Building, Room 312, 171 Ashley Avenue, Charleston, SC 29425, USA
    Antiviral Res 49:1-14. 2001
    The common cold is an important illness both as a result of the economic impact of this common disease and because of the morbidity associated with the complications of the illness...
  97. ncbi Mega-dose vitamin C in treatment of the common cold: a randomised controlled trial
    C Audera
    National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT
    Med J Aust 175:359-62. 2001
    OBJECTIVE: To determine the effect of large doses of vitamin C in the treatment of the common cold. STUDY DESIGN: Double-blind, randomised clinical trial with four intervention arms: vitamin C at daily doses of 0...
  98. ncbi Detection by reverse transcription-polymerase chain reaction of influenza C in nasopharyngeal secretions of adults with a common cold
    M Hirsilä
    Department of Medical Microbiology, University of Oulu, Oulu, Finland
    J Infect Dis 183:1269-72. 2001
    ..Two hundred otherwise healthy adults with recent onset of a common cold were studied. Nasopharyngeal aspirates were collected at entry to the study and 1 week later...
  99. ncbi Rhinoviruses in the pathogenesis of asthma
    Nikolaos G Papadopoulos
    Allergy Unit, Second Pediatric Clinic, University of Athens, 13 Levadias Street, 115 27 Goudi, Athens, Greece
    Curr Allergy Asthma Rep 3:137-45. 2003
    ..during the past decade have allowed the identification of human rhinoviruses (RVs), generally recognized as "common cold viruses," as major asthma precipitants...
  100. ncbi Virucidal hand treatments for prevention of rhinovirus infection
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA 22908, USA
    J Antimicrob Chemother 56:805-7. 2005
    Rhinovirus infections are associated with substantial morbidity and economic cost. The available common cold remedies are of limited utility and specific antiviral approaches have been unsuccessful...
  101. ncbi How viral infections cause exacerbation of airway diseases
    Patrick Mallia
    Department of Respiratory Medicine, National Heart and Lung Institute, Imperial College London, Norfolk Pl, London W2 1PG, UK
    Chest 130:1203-10. 2006
    ..In addition, such studies can identify new therapeutic targets for the development of novel drugs for the prevention and treatment of exacerbations...

Research Grants86

  1. MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATION
    JAMES FLANEGAN; Fiscal Year: 2007
    ..with these viruses include paralytic poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Post-polio syndrome is also an important clinical manifestation that occurs in patients 30-40 years after the ..
  2. Mechanisms of viral proteases in coronavirus replication and pathogenesis
    Andrew D Mesecar; Fiscal Year: 2010
    ..positive strand RNA viruses which cause a range of illness, from relatively mild respiratory disease (croup and common cold like symptoms due to HCoV- NL63, 229e or OC43) to severe acute respiratory syndrome (SARS) outbreaks in humans...
  3. Clinical Impact of Human Coronaviruses and Viral Diversity
    GEOFFREY GORSE; Fiscal Year: 2009
    ..The common cold, but also more severe illnesses involving the respiratory tract may result, including those similar to ..
  4. Control of cap-independent translation by a viral 3' UTR
    WYATT MILLER; Fiscal Year: 2009
    ..research may contribute to understanding mechanisms by which medically important viruses such as poliovirus, common cold rhinoviruses, the SARS virus, dengue virus, and West Nile viruses regulate gene expression and replication...
  5. Control of cap-independent translation by a viral 3' UTR
    WYATT MILLER; Fiscal Year: 2009
    ..research may contribute to understanding mechanisms by which medically important viruses such as poliovirus, common cold rhinoviruses, the SARS virus, dengue virus, and West Nile viruses regulate gene expression and replication...
  6. MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATION
    James Bert Flanegan; Fiscal Year: 2010
    ..with these viruses include paralytic poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Post-polio syndrome is also an important clinical manisfestation that occurrs in patients 30-40 years after ..
  7. MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATION
    JAMES FLANEGAN; Fiscal Year: 2006
    ..with these viruses include paralytic poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Post-polio syndrome is also an important clinical manifestation that occurs in patients 30-40 years after the ..
  8. MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATION
    JAMES FLANEGAN; Fiscal Year: 2009
    ..with these viruses include paralytic poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Post-polio syndrome is also an important clinical manisfestation that occurrs in patients 30-40 years after ..
  9. MOLECULAR BIOLOGY OF POLIOVIRUS RNA REPLICATION
    JAMES FLANEGAN; Fiscal Year: 2006
    ..associated with these viruses include poliomyelitis, meningitis, encephalitis, myocarditis, hepatitis and the common cold. Other positive-strand RNA viruses that form a large group of important human pathogens include hepatitis C ..
  10. Control of cap-independent translation by a viral 3' UTR
    WYATT ALLEN MILLER; Fiscal Year: 2010
    ..research may contribute to understanding mechanisms by which medically important viruses such as poliovirus, common cold rhinoviruses, the SARS virus, dengue virus, and West Nile viruses regulate gene expression and replication...
  11. Development of a novel human rhinovirus vaccine
    GREGORY JOHN TOBIN; Fiscal Year: 2010
    ..provided by applicant): Human Rhinoviruses (HRV) cause approximately one third of the 60 million cases of "common cold" each year in the US and therefore are one of the most economically important human diseases of developed ..
  12. Innovative Tools for In Vivo Computational Prediction of Lumbar Stresses
    Richard Komistek; Fiscal Year: 2009
    ..medical problem in the United States, and the second most common reason for doctor visits behind the common cold. Lower back pain is the leading cause of disability among people ages 19-45 and is the leading cause of missed ..
  13. Innovative Tools for In Vivo Computational Prediction of Lumbar Stresses
    Richard Komistek; Fiscal Year: 2007
    ..medical problem in the United States, and the second most common reason for doctor visits behind the common cold. Lower back pain is the leading cause of disability among people ages 19-45 and is the leading cause of missed ..
  14. Innovative Tools for In Vivo Computational Prediction of Lumbar Stresses
    RICHARD DAVID KOMISTEK; Fiscal Year: 2010
    ..medical problem in the United States, and the second most common reason for doctor visits behind the common cold. Lower back pain is the leading cause of disability among people ages 19-45 and is the leading cause of missed ..
  15. Innate Immunity in Otitis Media Pathogenesis
    David Lim; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Following the common cold, otitis media (OM), or inflammation of the middle ear, is the most frequent illness resulting in visits to physicians and the most common cause of hearing impairment and ..
  16. Innate Immunity in Otitis Media Pathogenesis
    David J Lim; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Following the common cold, otitis media (OM), or inflammation of the middle ear, is the most frequent illness resulting in visits to physicians and the most common cause of hearing impairment and ..
  17. PROTEIN STABILITY IN HUMAN RHINOVIRUS
    CAROL POST; Fiscal Year: 2002
    ..HRV is a member of the picornavirus family and the leading causative agent for the common cold. Other important human pathogens among the members of the picornaviruses are poliovirus, coxsackie virus and ..
  18. POLIOVIRUS AS A MODEL FOR THE DESIGN OF ANTIVIRAL DRUGS
    JAMES HOGLE; Fiscal Year: 1991
    ..These drugs would be of considerable medical and economic significance for prophylaxis of rhinovirus induced common cold (which account for up to 80% of the colds in the United States) and for early intervention in poliomyelitis and ..
  19. PROTEIN STABILITY IN HUMAN RHINOVIRUS
    CAROL POST; Fiscal Year: 2001
    ..HRV is a member of the picornavirus family and the leading causative agent for the common cold. Other important human pathogens among the members of the picornaviruses are poliovirus, coxsackie virus and ..
  20. PROTEIN STABILITY IN HUMAN RHINOVIRUS
    CAROL POST; Fiscal Year: 2005
    ..HRV is a member of the picornavirus family and the leading causative agent for the common cold. Other important human pathogens among the members of the picornaviruses are poliovirus, coxsackie virus and ..
  21. PROTEIN STABILITY IN HUMAN RHINOVIRUS
    CAROL POST; Fiscal Year: 2004
    ..HRV is a member of the picornavirus family and the leading causative agent for the common cold. Other important human pathogens among the members of the picornaviruses are poliovirus, coxsackie virus and ..
  22. PROTEIN STABILITY IN HUMAN RHINOVIRUS
    CAROL POST; Fiscal Year: 2003
    ..HRV is a member of the picornavirus family and the leading causative agent for the common cold. Other important human pathogens among the members of the picornaviruses are poliovirus, coxsackie virus and ..
  23. Rhinovirus-Induced Chemokine Production and Asthma
    James Gern; Fiscal Year: 2002
    ..production of interleukin-8 (IL-8) and RANTES correlates closely with cellular inflammation, the severity of common cold symptoms, and changes in airway hyperresponsiveness...
  24. CORONAVIRUS-RECEPTOR INTERACTIONS
    Kathryn Holmes; Fiscal Year: 2001
    ..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
  25. CORONAVIRUS-RECEPTOR INTERACTIONS
    Kathryn Holmes; Fiscal Year: 1999
    ..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
  26. EXPRESSION OF FUNCTIONAL POLIOVIRUS REPLICATION GENES
    CASEY MORROW; Fiscal Year: 1990
    ..This large group of medically important viruses includes agents of the common cold, infectious hepatitis and encephalomyocarditis...
  27. CORONAVIRUS-RECEPTOR INTERACTIONS
    Kathryn Holmes; Fiscal Year: 2000
    ..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
  28. CORONAVIRUS-RECEPTOR INTERACTIONS
    Kathryn Holmes; Fiscal Year: 2003
    ..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
  29. CORONAVIRUS-RECEPTOR INTERACTIONS
    Kathryn Holmes; Fiscal Year: 2002
    ..viruses that cause most common colds, such combination drugs would make it unnecessary to identify the type of common cold virus causing early symptoms before initiating therapy...
  30. EXPRESSION OF FUNCTIONAL POLIOVIRUS REPLICATION GENES
    CASEY MORROW; Fiscal Year: 1991
    ..This large group of medically important viruses includes agents of the common cold, infectious hepatitis and encephalomyocarditis...
  31. A Simulator for Sound Production in Airways
    Ingo Titze; Fiscal Year: 2007
    ..g. snoring, pediatric strider, croup, and several symptoms of influenza and the common cold)...
  32. A Simulator for Sound Production in Airways
    Ingo Titze; Fiscal Year: 2009
    ..g. snoring, pediatric strider, croup, and several symptoms of influenza and the common cold)...
  33. CONFERENCE ON POSITIVE-STRAND RNA VIRUSES
    MARGO BRINTON; Fiscal Year: 1992
    ..from positive-strand RNA virus infections includes encephalitis, poliomyelitis, heart disease, hepatitis, the common cold, gastroenteritis, hemorrhagic fever, and birth defects...
  34. A Simulator for Sound Production in Airways
    Ingo R Titze; Fiscal Year: 2010
    ..g. snoring, pediatric strider, croup, and several symptoms of influenza and the common cold)...
  35. Role of TLR4 in Coronavirus Infection
    STEVEN VARGA; Fiscal Year: 2009
    ..HCoVs) are positive-stranded RNA viruses that are estimated to account for approximately 30% of cases of the common cold. The emergence of a novel HCoV as the etiologic agent of severe acute respiratory syndrome (SARS) demonstrated ..
  36. Maximizing Expression of Immunoglobulins in Plants
    KEITH WYCOFF; Fiscal Year: 2010
    ..intoxication by Botulinum Neurotoxin A (BoNT/A), the most potent toxin known and a bio-terror agent, the common cold, dental caries and intoxication by Anthrax toxin, also a bio-terror agent...
  37. Role of TLR4 in Coronavirus Infection
    Steven M Varga; Fiscal Year: 2010
    ..HCoVs) are positive-stranded RNA viruses that are estimated to account for approximately 30% of cases of the common cold. The emergence of a novel HCoV as the etiologic agent of severe acute respiratory syndrome (SARS) demonstrated ..
  38. STRUCTURE OF A SMALL SPHERICAL VIRUS
    MICHAEL ROSSMANN; Fiscal Year: 1991
    ..is to compare the three-dimensional structures, at atomic resolution, of strains and mutants of rhino (common cold) viruses as well as other picornaviruses (particularly Mengo virus) in order to determine how their functions ..
  39. PICORNAVIRUS MOLECULAR BIOLOGY
    Eckard Wimmer; Fiscal Year: 2010
    ..These infections lead to a variety of diseases ranging from the mild (common cold) to the serious (poliomyelitis)...
  40. PICORNAVIRUS MOLECULAR BIOLOGY
    Eckard Wimmer; Fiscal Year: 2009
    ..These infections lead to a variety of diseases ranging from the mild (common cold) to the serious (poliomyelitis)...
  41. Transgenic Mouse Model for the Common Cold
    Matthias Gromeier; Fiscal Year: 2009
    ..Despite the generally benign course of the common cold caused by picornaviruses, it is the main culprit for acute exacerbation of serious respiratory system disorders,..
  42. CD4+ and CD8+ T cell dependent immune mechanisms of rhinovirus-mediated asthma ex
    Larry C Borish; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: The virus producing the "common cold" (rhinovirus) is responsible for most childhood and adolescent asthma exacerbations and, as such, most ..
  43. IN VITRO REPLICATION OF POLIOVIRUS
    Asim Dasgupta; Fiscal Year: 1990
    ..the remaining large gap in knowledge concerning replication of this medically important virus group which includes those inducing common cold, infectious hepatitis, encephalomyocarditis and foot-to-mouth disease in human and animals.
  44. ZINC GLUCONATE GLYCINE LOZENGES & VITAMIN C EFFECTS ON COMMON COLD
    Roberta Tankanow; Fiscal Year: 2000
    ..combination of zinc gluconate-glycine lozenges and vitamin C can decrease in the duration and severity of the common cold. A recent study indicated that zinc gluconate-glycine lozenges (13...
  45. A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CARE
    James Quinn; Fiscal Year: 2004
    DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
  46. ZINC GLUCONATE GLYCINE LOZENGES & VITAMIN C EFFECTS ON COMMON COLD
    Roberta Tankanow; Fiscal Year: 1999
    ..combination of zinc gluconate-glycine lozenges and vitamin C can decrease in the duration and severity of the common cold. A recent study indicated that zinc gluconate-glycine lozenges (13...
  47. A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CARE
    James Quinn; Fiscal Year: 2002
    DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
  48. A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CARE
    James Quinn; Fiscal Year: 2000
    DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
  49. A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CARE
    James Quinn; Fiscal Year: 2003
    DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
  50. A NETWORK OF RESEARCH UNITS TO STUDY CLINICAL WOUND CARE
    James Quinn; Fiscal Year: 2001
    DESCRIPTION (Taken from the applicants abstract): Next to the common cold, traumatic wounds are the most common reasons people seek medical care in the United States. An estimated 3...
  51. STRUCTURE OF POLIOVIRUS/ANTIVIRAL DRUG COMPLEXES
    JAMES HOGLE; Fiscal Year: 1991
    ..These drugs are of considerable medical and economic significance for prophylaxis of rhinovirus induced common cold (which account for 80% of the colds in the United States) and for early intervention in poliomyelitis and ..
  52. AIRWAY BIOLOGY OF RHINOVIRUS 16 INFECTION AND ASTHMA
    William Busse; Fiscal Year: 1993
    The rhinovirus (RV) common cold often provokes wheezing in patients with asthma...
  53. CONFERENCE ON POSITIVE-STRAND RNA VIRUSES
    MARGO BRINTON; Fiscal Year: 2001
    ..Human encephalitis, poliomyelitis, heart disease, hepatitis, the common cold, gastroenteritis, haemorrhagic fever, eye infections, and birth defects are caused by positive-strand RNA ..
  54. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 1999
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  55. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 2000
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  56. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 2002
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  57. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 2001
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  58. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 2003
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  59. LOW BACK PAIN--A MULTICENTER RANDOMIZED TRIAL
    James Weinstein; Fiscal Year: 2002
    ..S. and the world. This condition is second only to the common cold as the condition for which patients most frequently see a physician or suffer days lost from work...
  60. Phosphine-Catalyzed Annulations and Their Applications
    Ohyun Kwon; Fiscal Year: 2009
    ..The targets chosen are highly relevant to national public health, specifically the treatment of the common cold, hypertension, amoebic dysentery, malaria, arrhythmia, and cancer...
  61. TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    Asim Dasgupta; Fiscal Year: 1999
    ..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
  62. TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    Asim Dasgupta; Fiscal Year: 2003
    ..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
  63. Phosphine-Catalyzed Annulations and Their Applications
    Ohyun Kwon; Fiscal Year: 2006
    ..The targets chosen are highly relevant to national public health, specifically the treatment of the common cold, hypertension, amoebic dysentery, malaria, arrhythmia, and cancer...
  64. TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    Asim Dasgupta; Fiscal Year: 2002
    ..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
  65. Phosphine-Catalyzed Annulations and Their Applications
    Ohyun Kwon; Fiscal Year: 2010
    ..The targets chosen are highly relevant to national public health, specifically the treatment of the common cold, hypertension, amoebic dysentery, malaria, arrhythmia, and cancer...
  66. TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    Asim Dasgupta; Fiscal Year: 2000
    ..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
  67. TRANSLATION-INHIBITION OF HEPATITIS C AND POLIO VIRUSES
    Asim Dasgupta; Fiscal Year: 2001
    ..A) and chronic hepatitis (hepatitis C), common cold (rhinovirus), and myocarditis and encephalitis (coxsackie) among others...
  68. Targeting Oral Biofilms with 2-Aminoimidazole/Triazole Conjugates
    Eva Garland; Fiscal Year: 2010
    ..Dental caries, or tooth decay, affects hundreds of millions of people each year, and is second only to the common cold in its prevalence world-wide...
  69. Phosphine-Catalyzed Annulations and Their Applications
    Ohyun Kwon; Fiscal Year: 2007
    ..The targets chosen are highly relevant to national public health, specifically the treatment of the common cold, hypertension, amoebic dysentery, malaria, arrhythmia, and cancer...
  70. MOLECULAR STUDIES OF CORONAVIRUS REPLICATION
    Shinji Makino; Fiscal Year: 1990
    ..Coronaviruses are enveloped single-stranded, positive-sense RNA viruses which cause the common cold, gastroenteritis and demyelinating disease in man and livestock...
  71. CORONAVIRUS RNA SYNTHESIS--LYTIC & PERSISTENT INFECTIONS
    Stanley Sawicki; Fiscal Year: 1990
    In humans, coronaviruses are one of the viral agents causing the common cold and are implicated as the causative agent of necrotizing enterocolitis in newborns and of gastroenteritis in children and adults...
  72. BIOELASTIC MATERIAL TO PREVENT POST-LAMINECTOMY ADHESION
    Jie Xu; Fiscal Year: 2001
    ..APPLICATION: Low back pain, for which intervertebral disc pathology is the major cause, is second only to the common cold for work absenteeism in the United States; it is reported to result in more productivity loss than any other ..
  73. SYNTHETIC ANALOGUES OF ZINC ENZYMES
    Gerard Parkin; Fiscal Year: 2001
    ..effects on infectious diseases and zinc gluconate lozenges have been proposed to shorten the length of the common cold in adults...
  74. SYNTHETIC ANALOGUES OF ZINC ENZYMES
    Gerard Parkin; Fiscal Year: 2002
    ..effects on infectious diseases and zinc gluconate lozenges have been proposed to shorten the length of the common cold in adults...