respiratory tract neoplasms

Summary

Top Publications

  1. ncbi Incidence of HPV in primary and metastatic squamous cell carcinomas of the aerodigestive tract: implications for the establishment of clonal relationships
    C Will
    Histopathology 48:605-7. 2006
  2. ncbi A historical cohort mortality study among shipyard workers in Genoa, Italy
    R Puntoni
    Environmental Epidemiology and Biostatistics, National Cancer Institute, Largo Rosanna Benzi 19, 16132 Genoa, Italy
    Am J Ind Med 40:363-70. 2001
  3. ncbi Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco
    Sameer Jhavar
    Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Oral Oncol 40:84-91. 2004
  4. pmc Extending the p16-Leiden tumour spectrum by respiratory tract tumours
    R A Oldenburg
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    J Med Genet 41:e31. 2004
  5. ncbi The use of mitomycin-C for respiratory papillomas: clinical, histologic and biochemical correlation
    Ashraf H Hamza
    Otolaryngology HNS Department, Alexandria Faculty of Medicine, Al Ibrahemia, Alexandria, Egypt
    Saudi Med J 26:1737-45. 2005
  6. ncbi Cancer survival in Sweden 1960-1998--developments across four decades
    Mats Talbäck
    Centre for Epidemiology, The National Board of Health and Welfare, Stockholm, Sweden
    Acta Oncol 42:637-59. 2003
  7. ncbi Predictors of remission in juvenile-onset recurrent respiratory papillomatosis
    Snehal Ruparelia
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Arch Otolaryngol Head Neck Surg 129:1275-8. 2003
  8. ncbi Diagnosis and management of pulmonary metastasis from recurrent respiratory papillomatosis
    Robert D Silver
    Department of Otolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    Otolaryngol Head Neck Surg 129:622-9. 2003
  9. ncbi Recurrent respiratory papillomatosis
    M Shykhon
    Department of Otolaryngology, Birmingham Heartlands Hospital, UK
    Clin Otolaryngol Allied Sci 27:237-43. 2002
  10. ncbi Neck dissection shoulder syndrome: quantification and three-dimensional evaluation with an optoelectronic tracking system
    Marco Caversaccio
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Inselspital, University of Bern, Bern, Switzerland
    Ann Otol Rhinol Laryngol 112:939-46. 2003

Research Grants

Detail Information

Publications129 found, 100 shown here

  1. ncbi Incidence of HPV in primary and metastatic squamous cell carcinomas of the aerodigestive tract: implications for the establishment of clonal relationships
    C Will
    Histopathology 48:605-7. 2006
  2. ncbi A historical cohort mortality study among shipyard workers in Genoa, Italy
    R Puntoni
    Environmental Epidemiology and Biostatistics, National Cancer Institute, Largo Rosanna Benzi 19, 16132 Genoa, Italy
    Am J Ind Med 40:363-70. 2001
    ..These workers were exposed to asbestos fibers, welding fumes and gases, silica dust, polycyclic aromatic hydrocarbons, and solvents...
  3. ncbi Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco
    Sameer Jhavar
    Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Oral Oncol 40:84-91. 2004
    ..All three patients with a family history of UADT cancer developed MPN, suggesting an inherited predisposition...
  4. pmc Extending the p16-Leiden tumour spectrum by respiratory tract tumours
    R A Oldenburg
    Center of Human and Clinical Genetics, Leiden University Medical Center, Leiden, The Netherlands
    J Med Genet 41:e31. 2004
  5. ncbi The use of mitomycin-C for respiratory papillomas: clinical, histologic and biochemical correlation
    Ashraf H Hamza
    Otolaryngology HNS Department, Alexandria Faculty of Medicine, Al Ibrahemia, Alexandria, Egypt
    Saudi Med J 26:1737-45. 2005
    ..To assess the clinical effects of mitomycin-C (MMC) on human papilloma virus (HPV)-infected tissues of the airway...
  6. ncbi Cancer survival in Sweden 1960-1998--developments across four decades
    Mats Talbäck
    Centre for Epidemiology, The National Board of Health and Welfare, Stockholm, Sweden
    Acta Oncol 42:637-59. 2003
    ..Survival for breast and cervical cancer also improved during the 1990s, but not that for pancreatic, liver or lung cancer...
  7. ncbi Predictors of remission in juvenile-onset recurrent respiratory papillomatosis
    Snehal Ruparelia
    Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Arch Otolaryngol Head Neck Surg 129:1275-8. 2003
    ..To determine factors associated with remission of juvenile-onset recurrent respiratory papillomatosis (JORRP)...
  8. ncbi Diagnosis and management of pulmonary metastasis from recurrent respiratory papillomatosis
    Robert D Silver
    Department of Otolaryngology Head and Neck Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    Otolaryngol Head Neck Surg 129:622-9. 2003
    ..We sought to review the current and proposed management, as well as bring about discussion, of managing the patient with distal tracheal and pulmonary parenchymal involvement by recurrent respiratory papillomatosis (RRP)...
  9. ncbi Recurrent respiratory papillomatosis
    M Shykhon
    Department of Otolaryngology, Birmingham Heartlands Hospital, UK
    Clin Otolaryngol Allied Sci 27:237-43. 2002
    ..Unfortunately, despite extensive investigational studies, no cure is available for the disease. This article reviews the aetiology of and therapeutic options for recurrent respiratory papillomatosis...
  10. ncbi Neck dissection shoulder syndrome: quantification and three-dimensional evaluation with an optoelectronic tracking system
    Marco Caversaccio
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Inselspital, University of Bern, Bern, Switzerland
    Ann Otol Rhinol Laryngol 112:939-46. 2003
    ..The Constant scores were significantly lower after RND than after MRND (p < .01). Three-dimensional evaluation of the shoulder syndrome supports the Constant score, quantifying what can be measured objectively...
  11. ncbi Lower airway papillomatosis in children
    Lidia Zawadzka-Głos
    Department of Paediatric Otorhinolaryngology, The Medical University of Warsaw, 24 Marszałkowska Str, 00 576 Warsaw, Poland
    Int J Pediatr Otorhinolaryngol 67:1117-21. 2003
    ..In differential diagnosis of these changes in the lungs we should take into consideration the presence of papilloma in the bronchi. A prognosis of papillomatosis in the lower airways in children is always serious...
  12. ncbi Cancer incidence among union carpenters in New Jersey
    John Dement
    Division of Occupational and Environmental Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    J Occup Environ Med 45:1059-67. 2003
    ..48) in analyses that lagged results 15 years from initial union membership. Additional etiologic research is needed to evaluate possible occupational and nonoccupational risk factors for testicular cancer...
  13. ncbi Carotid artery invasion by squamous cell carcinoma of the upper aerodigestive tract: the predictive value of CT imaging
    P A Nix
    ENT SpR Yorkshire Region, Academic Surgical Unit, Research and Development Building, Castle Hill Hospital, Cottingham HU16 5JQ, UK
    Int J Clin Pract 57:628-30. 2003
    ..Comparing the scans with the operative findings indicates that CT scans significantly overestimate carotid artery invasion...
  14. ncbi The potential health and economic benefits of preventing recurrent respiratory papillomatosis through quadrivalent human papillomavirus vaccination
    Harrell W Chesson
    Division of STD Prevention, National Center for HIV AIDS, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Vaccine 26:4513-8. 2008
    ..More precise estimates of the incidence of RRP are needed, however, to quantify this impact more reliably...
  15. ncbi Cidofovir efficacy in recurrent respiratory papillomatosis: a randomized, double-blind, placebo-controlled study
    J Scott McMurray
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792, USA
    Ann Otol Rhinol Laryngol 117:477-83. 2008
    ..Although results of case series suggest that cidofovir may decrease the frequency and rapidity of papilloma regrowth, no blinded placebo-controlled studies have demonstrated efficacy...
  16. ncbi Four mutations in Epidermodysplasia verruciformis 1 (EVER1) gene are not contributors to susceptibility in RRP
    Joseph Donfack
    Allegheny General Hospital, Allegheny Singer Research Institute, 320 East North Avenue, 11th Floor, South Tower, Room 1171, Pittsburgh, PA 15212 4772, USA
    Int J Pediatr Otorhinolaryngol 70:1235-40. 2006
    ....
  17. ncbi Epidermal growth factor-induced cyclooxygenase-2 expression is mediated through phosphatidylinositol-3 kinase, not mitogen-activated protein/extracellular signal-regulated kinase kinase, in recurrent respiratory papillomas
    Rong Wu
    Institute for Medical Research, North Shore Long Island Jewish Health System, Manhasset, New York, USA
    Clin Cancer Res 11:6155-61. 2005
    ....
  18. ncbi Voice quality of prepubescent children with quiescent recurrent respiratory papillomatosis
    Jonathan P Lindman
    Department of Surgery, University of Alabama at Birmingham, Birmingham, AL 35243, USA
    Int J Pediatr Otorhinolaryngol 68:529-36. 2004
    ..The purpose of this study was to assess the long-term impact of recurrent respiratory papillomatosis (RRP) and its treatment on voice quality in prepubescent children...
  19. ncbi Human papillomavirus DNA presence of the upper respiratory tract mucosa of healthy children
    Jarosław Szydłowski
    ENT Department of Pediatric, Institute of the Karol Marcinkowski, University of Medical Sciences of Poznan
    Otolaryngol Pol 58:211-5. 2004
    ..The presence of HPV in respiratory tract in children is relatively high. "High risk" HPV are not observed in the respiratory tract in children. The Human Papillomavirus in children may be transmitted by direct contacts...
  20. ncbi Human papilloma virus (HPV)-associated gynecological alteration in mothers of children with recurrent respiratory papillomatosis during long-term observation
    Valentin Gerein
    Department of Pediatric Pathology, Institute of Pathology, University of Mainz, Germany
    Cancer Detect Prev 31:276-81. 2007
    ..The study' purpose was to investigate the relation between a mother's gynecological history and the local status of her child with recurrent respiratory papillomatosis (RRP)...
  21. ncbi Cidofovir for the treatment of recurrent respiratory papillomatosis: a review of the literature
    Nadine Shehab
    Department of Pharmacy Services, University of Michigan Health System, University Hospital, Ann Arbor, Michigan 48109 0008, USA
    Pharmacotherapy 25:977-89. 2005
    ..Further studies are necessary to determine the most appropriate dose, frequency, and duration of therapy, and to fully characterize the safety profile profile of cidofovir when given intralesionally...
  22. pmc Regional, disease specific patterns of smoking-attributable mortality in 2000
    M Ezzati
    Harvard School of Public Health, Population and International Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA
    Tob Control 13:388-95. 2004
    ..Mortality attributable to smoking in the year 2000 was estimated for adult males and females, including estimates by age and for specific diseases in 14 epidemiological subregions of the world...
  23. ncbi 2',5'-Oligoadenylate synthetase activity analysis and human papilloma virus typing as prognostic factors in patients with recurrent respiratory papillomatosis
    V Gerein
    Department of Paediatric Pathology, Institute of Pathology, Johannes Gutenberg University of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    J Laryngol Otol 118:750-6. 2004
    ....
  24. ncbi Current diagnostic and management trends for recurrent respiratory papillomatosis
    Damon A Silverman
    Division of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Vermont College of Medicine, Burlington, Vermont, USA
    Curr Opin Otolaryngol Head Neck Surg 12:532-7. 2004
    ..This includes a discussion of new information regarding the epidemiology and pathogenesis of RRP and an update on adjuvant therapy and new surgical techniques...
  25. ncbi Recurrent respiratory papillomatosis: cytopathological findings in an unusual case
    Anil V Parwani
    Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287 6417, USA
    Diagn Cytopathol 31:407-12. 2004
    ..To our knowledge, morphological findings of RRP have been reported rarely...
  26. ncbi Interferon alpha-2b as adjuvant treatment of recurrent respiratory papillomatosis in Cuba: National Programme (1994-1999 report)
    Hugo Nodarse-Cuní
    Centro de Investigaciones Biologicas, La Habana, Cuba
    J Laryngol Otol 118:681-7. 2004
    ..Treatment with IFN alpha-2b, as an adjuvant to surgery represents a favourable and safe therapeutic alternative for patients with recurrent respiratory papillomatosis...
  27. ncbi American Society of Pediatric Otolaryngology members' experience with recurrent respiratory papillomatosis and the use of adjuvant therapy
    Scott Schraff
    Eastern Virginia Medical School and the Children s Hospital of the King s Daughters, Norfolk, VA 23507 1914, USA
    Arch Otolaryngol Head Neck Surg 130:1039-42. 2004
    ..To evaluate how evolving treatment technologies have affected our management of recurrent respiratory papilloma (RRP) since the last comprehensive survey of pediatric otolaryngologists in 1998...
  28. ncbi [Diagnostic imaging of cancer]
    Mária Godény
    Országos Onkológiai Intézet, Budapest 1122, Hungary
    Magy Onkol 48:167-90. 2004
    ..The comprehensive cancer centers with all the necessary imaging techniques are the optimal organizations where professional and economic priorities both can be considered for the benefit of cancer patients...
  29. ncbi HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosis
    Vincent R Bonagura
    Division of Allergy and Immunology, North Shore Long Island Jewish Research Institute, Department of Pediatrics, Long Island Jewish Medical Center, New Hyde Park, New York, USA
    Hum Immunol 65:773-82. 2004
    ....
  30. ncbi Recurrent respiratory papillomatosis in a survivor of extreme prematurity
    S L Lee
    Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Pediatr Pulmonol 38:352-4. 2004
    ..5 years. RRP should be considered in the differential diagnosis of airway problems in survivors of extreme prematurity; the prognosis is not uniformly poor in premature infants...
  31. ncbi Children and partners of patients with recurrent respiratory papillomatosis have no evidence of the disease during long-term observation
    Valentin Gerein
    Department of Pediatric Pathology, Institute of Pathology, Johannes Gutenberg University of Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    Int J Pediatr Otorhinolaryngol 70:2061-6. 2006
    ..The aim of our study was to investigate whether children and partners of patients with RRP develop the same disease and to determine whether there is an impact of pregnancy on the course of RRP...
  32. ncbi Clinical course of recurrent respiratory papillomatosis in Danish children
    Michael J Silverberg
    Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Arch Otolaryngol Head Neck Surg 130:711-6. 2004
    ..To evaluate the clinical course of juvenile-onset recurrent respiratory papillomatosis (RP) with respect to age, disease duration, and maternal condylomas...
  33. ncbi Indole-3-carbinol for recurrent respiratory papillomatosis: long-term results
    Clark A Rosen
    University of Pittsburgh Voice Center, Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Voice 18:248-53. 2004
    ..No immediate or long-term side effects related to I3C were found. I3C has been found to be a successful treatment option for RRP. I3C's efficacy in pediatric patients merits further study...
  34. ncbi Analysis of sex, age and disease factors contributing to prolonged life expectancy at birth, in cases of malignant neoplasms in Japan
    Tomoyuki Watanabe
    Graduate School of Medicine, Nagoya University, Japan
    J Epidemiol 13:169-75. 2003
    ..This study aimed to examine the contribution made by the change in mortality from malignant neoplasms to the life expectancy at birth, observed during the years 1965-1995 in Japan...
  35. ncbi Transbronchial needle injection: a systematic review of a new diagnostic and therapeutic paradigm
    Christopher W Seymour
    Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    Respiration 73:78-89. 2006
    ..Transbronchial needle catheters are commonly used during flexible and rigid bronchoscopy for needle aspiration. The use of these catheters can be expanded by employing the technique of transbronchial needle injection...
  36. ncbi Bronchoscopic management of benign stenosis
    S M Shapshay
    Department of Otolaryngology-Head and Neck Surgery, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    Chest Surg Clin N Am 11:749-68. 2001
    ..As usual, patient selection is one of the key factors related to successful management...
  37. ncbi Collagen matrix in development and progression of experimentally induced respiratory neoplasms in the hamster
    J Laitakari
    Department of Pathology, University of Oulu, Finland
    Toxicol Pathol 29:514-27. 2001
    ..The nature of the composition of the ECM was related to neoplastic growth and progression when analyzed by computer-associated image analysis, revealing alterations in collagen structure, size, and shape...
  38. ncbi Morphometric characteristics of cell proliferation and p53 expression in development of experimentally induced respiratory tumors
    J Laitakari
    Department of Pathology, University of Oulu, Finland
    Anal Quant Cytol Histol 23:273-86. 2001
    ..CONCLUSION: Computer-assisted analysis of immunohistochemical staining showed high sensitivity and reproducibility; however, the results depended upon the method of study...
  39. pmc Socioeconomic inequalities in alcohol related cancer mortality among men: to what extent do they differ between Western European populations?
    Gwenn Menvielle
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Int J Cancer 121:649-55. 2007
    ..This study suggests that alcohol use substantially influences socioeconomic inequalities in male cancer mortality in France, Spain and Switzerland but not in the Nordic countries and nor in Belgium...
  40. ncbi Topoisomerase alpha II, retinoblastoma gene product, and p53: potential relationships with aggressive behavior and malignant transformation in recurrent respiratory papillomatosis
    D Gupta
    Department of Pathology, University of Utah Health Sciences Center, Salt Lake City 84132, USA
    Appl Immunohistochem Mol Morphol 9:86-91. 2001
    ..Increased topoisomerase alpha II and p53 expression along with reduced RB gene protein product and p21 expression may serve as markers of transformation to invasive papillomatosis and squamous carcinoma...
  41. ncbi Recurrent respiratory papillomatosis with pulmonary involvement
    Marcos Hiroyuki Ikawa
    Departamento de Diagnóstico por Imagem, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP
    Rev Soc Bras Med Trop 41:89-90. 2008
  42. ncbi Immunocompetency in children with recurrent respiratory papillomatosis: prospective study
    Yoram Stern
    Dept of Pediatric Otolaryngology, Schneider Children s Medical Center of Israel, Petah Tiqwa 49202, Israel
    Ann Otol Rhinol Laryngol 116:169-71. 2007
    ..We sought to investigate the immunologic status of children with recurrent respiratory papillomatosis and to evaluate possible correlations between the patients' immunocompetency and the clinical course of the disease...
  43. ncbi Epidemiology of alcohol-associated cancers
    Linda Morris Brown
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Boulevard, Room 8026, MSC 7244, Bethesda, MD 20892 7244, USA
    Alcohol 35:161-8. 2005
    ..S. minority populations, to enhance experimental work to better understand the underlying mechanisms through which alcohol promotes carcinogenesis, and to develop preventive strategies...
  44. pmc The epidemiology of human papillomavirus infection and cervical cancer
    F Xavier Bosch
    Institut Catala d Oncologia, Epidemiology and Cancer Registration Unit, E 08907 L Hospitalet de Llobregat, Barcelona, Spain
    Dis Markers 23:213-27. 2007
    ..Women exposed to the Human Immunodeficiency Virus (HIV) are at high risk for HPV infection, HPV DNA persistency and progression of HPV lesions to cervical cancer...
  45. ncbi Protein expression of the tumor suppressors p16INK4A and p53 and disease progression in recurrent respiratory papillomatosis
    Truc T Pham
    Department of Pathology, University of California San Diego, San Diego, California, USA
    Laryngoscope 117:253-7. 2007
    ..Although this disease is associated with human papillomavirus, the role of this virus in tumorigenesis is unclear...
  46. ncbi Powered instrumentation in the treatment of recurrent respiratory papillomatosis: an alternative to the carbon dioxide laser
    Mohamed A el-Bitar
    Children s National Medical Center, 111 Michigan Ave NW, Washington, DC 20010, USA
    Arch Otolaryngol Head Neck Surg 128:425-8. 2002
    ..To assess the advantages of powered instrumentation vs the carbon dioxide laser in treating patients with juvenile-onset recurrent respiratory papillomatosis...
  47. pmc Recurrent respiratory papillomatosis
    R A Tasca
    Leighton Hospital, Crewe, UK
    Arch Dis Child 91:689-91. 2006
    ..Affected children usually require multiple interventions; the impact on patients, their families, and the healthcare system is considerable. Treatment of RRP accounts for an estimated dollar 109 million annual expenditure in the USA...
  48. ncbi Cannabis use and cancer
    Wayne Hall
    Addiction 97:243-7. 2002
  49. ncbi Prevention of recurrent respiratory papillomatosis: role of HPV vaccination
    Gary L Freed
    Department of Otolaryngology, Eastern Virginia Medical School, 825 Fairfax Avenue, Suite 510, Norfolk, VA 23507, United States
    Int J Pediatr Otorhinolaryngol 70:1799-803. 2006
    ..With the possibility this could drastically reduce the incidence of RRP, the otolaryngology community should advocate for implementation of a vaccine program that provides effective prevention of HPV infection with subtypes 6 and 11...
  50. ncbi Marijuana use and the risk of lung and upper aerodigestive tract cancers: results of a population-based case-control study
    Mia Hashibe
    IARC, Lyon, France
    Cancer Epidemiol Biomarkers Prev 15:1829-34. 2006
    ..We conducted a population-based case-control study of the association between marijuana use and the risk of lung and upper aerodigestive tract cancers in Los Angeles...
  51. ncbi [Smoking and alcohol: a deadly combination]
    F Mihaltan
    Institutul de Pneumologie M Nasta Bucureşti
    Pneumologia 55:80-4. 2006
  52. ncbi Novel treatments for recurrent respiratory papillomatosis
    Christine Armbruster
    Mantlergasse 23 2 12, A 1130 Vienna, Austria
    Expert Opin Investig Drugs 11:1139-48. 2002
    ..This review focuses on the current status of recurrent respiratory papillomatosis and on future directions of prevention and therapy...
  53. ncbi Advocating for the quadravalent HPV vaccination, Gardasil, by Merck
    Barbara Elaine Rothengass
    Int J Pediatr Otorhinolaryngol 71:671-2; authore reply 673. 2007
  54. ncbi A retrospective analysis of the use of brachytherapy in relation to early stage squamous cell carcinoma of the oropharynx and its relationship to second primary respiratory and upper digestive tract cancers
    M Kishino
    Department of Radiology, Graduate School, Tokyo Medical and Dental University Hospital, Tokyo Medical and Dental University, Tokyo, Japan
    Br J Radiol 80:121-5. 2007
    ..We concluded that our treatment policy of brachytherapy with or without external irradiation for patients with early stage SCO was effective and acceptable from the standpoint of tumour control and post-treatment QOL...
  55. ncbi [The indication of panendoscopy in the search for synchronous and metachronous head and neck cancer]
    N Dulguerov
    Unite de chirurgie cervico faciale Service d ORL et de chirurgie cervico faciale HUG, 1211 Geneve 14
    Rev Med Suisse 9:1770, 1772-4. 2013
    ..During follow-up, metachronous malignancy should be searched for in the head and neck region; investigation beyond the head and neck is questionable since prognosis is poor...
  56. pmc Recurrent respiratory papillomatosis
    Naren N Venkatesan
    Department of Otolaryngology, University of Texas Medical Branch, 7 104 John Sealy Annex, 301 University Boulevard, Galveston, TX 77555 0521, USA
    Otolaryngol Clin North Am 45:671-94, viii-ix. 2012
    ..Clinical presentation of initial symptoms of RRP may be subtle. RRP course varies, and current management focuses on surgical debulking of papillomatous lesions with or without concurrent adjuvant therapy...
  57. ncbi A complicated, metastatic, humeral air sac cystadenocarcinoma in a timneh African grey parrot (Psittacus erithacus timneh)
    Panagiotis Azmanis
    Clinic for Birds and Reptiles, University of Leipzig An den Tierkliniken, 17, 04103, Leipzig, Germany
    J Avian Med Surg 27:38-43. 2013
    ....
  58. pmc Immune suppression in premalignant respiratory papillomas: enriched functional CD4+Foxp3+ regulatory T cells and PD-1/PD-L1/L2 expression
    Lynda J Hatam
    The Feinstein Institute for Medical Research, 350 Community Drive, Room 1239, Manhasset, NY 11030, USA
    Clin Cancer Res 18:1925-35. 2012
    ..To illuminate why patients with recurrent respiratory papillomatosis (RRP) fail to effectively control their disease, we further investigated the suppressive cellular microenvironment in papillomas...
  59. pmc Propranolol is an effective treatment for airway haemangiomas: a critical analysis and meta-analysis of published interventional studies
    P V Vlastarakos
    ENT Deptartment, Lister Hospital, Stevenage, UK
    Acta Otorhinolaryngol Ital 32:213-21. 2012
    ..Children should remain on propranolol until the haemangioma enters the phase of involution. Active parental monitoring is essential to ensure treatment safety...
  60. doi [Aero-digestive tract squamous intra-epithelial neoplasia]
    Sébastien Duquenne
    Laboratoire d Anatomie Pathologique, CHU de Liege, 1, Avenue de l Hopital, 4000 Liege, Belgique
    Ann Pathol 33:102-9. 2013
    ..This publication aims to review the molecular alterations which have been identified in these lesions, to clarify the clinical manifestations and to discuss the proposed histological classification...
  61. doi Neoplastic severe central airways obstruction, interventional bronchoscopy: a decision-making analysis
    Venceslau Hespanhol
    Pulmonary Service, Hospital S João Medical Center, Porto, Portugal
    J Thorac Cardiovasc Surg 145:926-32. 2013
    ..This study focuses on the development of a predictive preintervention model that is useful when deciding whether to perform therapeutic interventional bronchoscopy in patients with severe central airway obstruction...
  62. pmc Mentholated cigarettes and smoking-related cancers revisited: an ecologic examination
    Geoffrey C Kabat
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Regul Toxicol Pharmacol 63:132-9. 2012
    ....
  63. doi Congenital pulmonary airway malformation with mucoepidermoid carcinoma: a case report and review of literature
    Narayanappa Harini
    Department of Pathology, Apollo Hospitals, Chennai, India
    Indian J Pathol Microbiol 55:540-2. 2012
    ..We report the first case of mucoepidermoid carcinoma arising in a type 1 CCAM...
  64. ncbi HspE7 treatment of pediatric recurrent respiratory papillomatosis: final results of an open-label trial
    Craig S Derkay
    Department of Otolaryngology Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, Virginia, USA
    Ann Otol Rhinol Laryngol 114:730-7. 2005
    ....
  65. ncbi Unique challenges of obtaining regulatory approval for a multicenter protocol to study the genetics of RRP and suggested remedies
    Mylaina L Sherwood
    Center for Genomic Sciences at Allegheny Singer Research Institute, Allegheny General Hospital, 320 East North Avenue, Pittsburgh, PA 15212 4772, USA
    Otolaryngol Head Neck Surg 135:189-96. 2006
    ..This study describes the process of obtaining regulatory approval for a minimal risk genetic study in a multi-center setting as undertaken by the Recurrent Respiratory Papillomatosis (RRP) Task Force...
  66. ncbi Tumour biology and histopathology of neuroendocrine tumours
    Gunter Kloppel
    Department of Pathology, University of Kiel, Michaelisstr 11, 24105 Kiel, Germany
    Best Pract Res Clin Endocrinol Metab 21:15-31. 2007
    ..Their clinical behaviour--ranging from benign and low-grade to high-grade malignancy--can be predicted on the basis of clinicopathological criteria. Currently extensive work is being performed to unravel the genetic background...
  67. ncbi Surgical management of well-differentiated thyroid cancer locally invasive to the respiratory tract
    Anthony W Kim
    Department of Cardiovascular and Thoracic Surgery, Rush University Medical Center, Chicago, IL 60612, USA
    J Am Coll Surg 201:619-27. 2005
  68. ncbi [Carcinoembryonic antigen (CEA)]
    Tetsushi Kinugasa
    Department of Biochemistry, Fukuoka University School of Medicine
    Nihon Rinsho 63:632-4. 2005
  69. ncbi Creating a medical home for the child with recurrent respiratory papillomatosis
    Deborah S Rosenberg
    National Recurrent Respiratory Papillomatosis Task Force, USA
    ORL Head Neck Nurs 26:8-15. 2008
    ..Comprehensive primary care is described for children with recurrent respiratory papillomatosis, including well child care, episodic illness management, and care coordination...
  70. ncbi Thoracoscopy in infants and children
    S S Rothenberg
    Department of Surgery, The Hospital for Infants and Children at Presbyterian St Lukes, Denver, CO 80218, USA
    Semin Pediatr Surg 7:194-201. 1998
    ..With continued improvement and miniaturization of the equipment, the procedures we can perform and the advantages to the patient should continue to grow...
  71. pmc Genital HPVs in the aerodigestive tract: etiologic association with a subset of oropharyngeal/tonsillar cancers and with recurrent respiratory papillomatosis
    Keerti V Shah
    Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA
    Dis Markers 23:235-45. 2007
  72. pmc The economic burden of noncervical human papillomavirus disease in the United States
    Delphine Hu
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Obstet Gynecol 198:500.e1-7. 2008
    ....
  73. ncbi Degrees of dysplasia and the use of cidofovir in patients with recurrent respiratory papillomatosis
    Hina T Gupta
    Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Laryngoscope 120:698-702. 2010
    ..This study aims to explore the association between increasing degree of papilloma dysplasia and the use of cidofovir in the context of the natural progression of dysplasia in RRP...
  74. ncbi Re: particulate matter, science and European Union policy
    F Cetta
    Eur Respir J 30:805-6. 2007
  75. ncbi Malignant respiratory-digestive fistulas
    Alicia N Rodriguez
    Department of Pulmonary Medicine, Clinica Colon Mar del Plata, Mar del Plata, Argentina
    Curr Opin Pulm Med 16:329-33. 2010
    ..Patients present mainly with intractable cough and repeated respiratory infections. Rapid deterioration and death results if this condition is left untreated...
  76. ncbi The epidemiology and treatment of mesothelioma in South East England 1985-2002
    V Mak
    King s College London, Thames Cancer Registry, London, UK
    Thorax 63:160-6. 2008
    ..To describe treatment patterns by cancer network of residence, and relative survival by cancer network, disease stage and treatment modality...
  77. doi Bayesian hierarchical modeling of latent period switching in small-area putative health hazard studies
    Ahmed Al-Hadhrami
    Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA
    Stat Methods Med Res 20:5-28. 2011
    ..The developed methodology is applied in a simulation study as well as to a real data example...
  78. doi Cidofovir: to use or not to use?
    Marlene A Soma
    Department of Otolaryngology Head and Neck Surgery, Great Ormond St Hospital for Children, London, UK
    Curr Opin Otolaryngol Head Neck Surg 16:86-90. 2008
    ..This review examines recent publications for evidence of safety and efficacy...
  79. doi Sarcomatoid carcinoma of the upper aerodigestive tract: an immunohistochemical analysis demonstrating latent Epstein-Barr virus in a subset of eight cases
    Demet Etit
    Department of Pathology, Tepecik Research and Training Hospital, Izmir, Turkey
    Indian J Pathol Microbiol 53:750-6. 2010
    ..Sarcomatoid or spindle cell carcinomas are rare malignancies which are considered as a poorly differentiated variant of squamous cell carcinoma. Epstein-Barr virus (EBV) is associated with a wide variety of malignancies...
  80. doi Clinical spectrum and risk of PHACE syndrome in cutaneous and airway hemangiomas
    Anita N Haggstrom
    Department of Dermatology, Indiana University, 550 N University Blvd, UH 3240, Indianapolis, IN 46202, USA
    Arch Otolaryngol Head Neck Surg 137:680-7. 2011
    ..To describe the clinical presentation and risk of PHACE syndrome in infants with large facial hemangiomas and concomitant airway hemangiomas...
  81. ncbi Dysplasia in adults with recurrent respiratory papillomatosis: incidence and risk factors
    Joel H Blumin
    Division of Laryngology and Professional Voice, Department of Otolaryngology and Communication Sciences Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Ann Otol Rhinol Laryngol 118:481-5. 2009
    ..The incidence of dysplasia in adult patients with RRP has not been well described. In this study, the risk factors and incidence of RRP-associated dysplasia are investigated...
  82. doi Reconstruction of historical exposures in the US nickel alloy industry and the implications for carcinogenic hazard and risk assessments
    Donna J Sivulka
    DJS Consulting, 3942 Rives Chapel Rd, Siler City, NC 27344, USA
    Regul Toxicol Pharmacol 53:174-85. 2009
    ..This suggests that extrapolating risks from certain primary nickel producers to other nickel industry sectors may not be appropriate...
  83. doi [Anesthetic management in laryngotracheal surgery. High-frequency jet ventilation as strategy for ventilation during general anesthesia]
    K Fritzsche
    Klinik für Anästhesiologie und Intensivtherapie, Medizinische Fakultät TU Dresden
    Anaesthesist 59:1051-61; quiz 1062-3. 2010
    ..A particular challenge for the anesthesiologist is the use of HFJV during laryngeal laser surgery...
  84. doi Unusual thoracic CT manifestations of osteosarcoma: review of 16 cases
    Ruchi Rastogi
    Department of Radiology, All India Institute of Medical Sciences, New Delhi, India 110029
    Pediatr Radiol 38:551-8. 2008
    ..Our findings of lymphangitic carcinomatosis in a living patient as well as calcified mediastinal lymphadenopathy leading to esophageal fistula are unique in the literature, and there are only a few case reports of our other findings...
  85. pmc Incense use and respiratory tract carcinomas: a prospective cohort study
    Jeppe T Friborg
    The Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, USA
    Cancer 113:1676-84. 2008
    ..Therefore, the relation between incense use and the risk of respiratory tract carcinomas was analyzed in a prospective cohort study...
  86. doi Cancers of the head and neck
    Hans Krueger
    Cancer Prevention Programs, BC Cancer Agency, Vancouver, BC, Canada
    Prog Exp Tumor Res 40:62-84. 2008
  87. ncbi Cytokine pattern in Kaposi's sarcoma associated with immune restoration disease in HIV and tuberculosis co-infected patients
    Jerome Tamburini
    Department of Infectious Diseases, Pitie Salpetriere Hospital, Paris, France
    AIDS 21:1980-3. 2007
    ..Analysis of VEGF and pro-inflammatory cytokines led us to hypothesize that Kaposi's sarcoma could be promoted by the tuberculosis immune response...
  88. ncbi Impact of prophylactic human papillomavirus vaccines on dermatology and venereology
    G Gross
    Department of Dermatology and Venereology, University of Rostock, Rostock, Germany
    G Ital Dermatol Venereol 143:259-65. 2008
    ..HPV disease can be widespread, chronic and often may rapidly progress to malignant tumors. Thus, these individuals would greatly benefit from prophylactic HPV immunization...
  89. doi Recurrent respiratory papillomatosis: update 2008
    Thomas Q Gallagher
    Department of Otolaryngology Head and Neck Surgery, Naval Medical Center, Portsmouth, USA
    Curr Opin Otolaryngol Head Neck Surg 16:536-42. 2008
    ..Over the past several years some exciting new therapeutic options as well as some relevant research into the disease process has emerged that may offer new insight and methods in managing this frustrating disease...
  90. pmc Respiratory cancer and inhaled inorganic arsenic in copper smelters workers: a linear relationship with cumulative exposure that increases with concentration
    Jay H Lubin
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Environ Health Perspect 116:1661-5. 2008
    ....
  91. ncbi Do human papillomavirus vaccines have any role in newborns and the prevention of recurrent respiratory papillomatosis in children?
    Andrea Schaffer
    National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children s Hospital at Westmead and the University of Sydney, NSW, Australia
    J Paediatr Child Health 43:579-80. 2007
  92. ncbi [The burden of neoplasm in Brazil: mortality and hospital morbidity from 2002 to 2004]
    Antonio Fernando Boing
    Departamento de Saude Publica, Universidade Federal de Santa Catarina
    Rev Assoc Med Bras 53:317-22. 2007
    ..To describe mortality and the hospital morbidity by neoplasias in Brazil and regions according to gender...
  93. ncbi The effect of stress-reducing, low-dose ethanol infusion on frequency of bleeding complications in long-term alcoholic patients undergoing major surgery
    Helge Schoenfeld
    Department of Anesthesiology and Intensive Care Medicine, Charite Universitaetsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Am Surg 73:192-8. 2007
    ..In contrast, ethanol infusion in patients with tumor resections in the gastrointestinal tract could increase the risk for bleeding complications...
  94. ncbi Cancer mortality in a cohort of male German iron foundry workers
    Karl Heinrich Adzersen
    German Cancer Research Center DKFZ, Division of Clinical Epidemiology, Heidelberg, Germany
    Am J Ind Med 43:295-305. 2003
    ..The purpose of the study was to examine whether occupational exposure in iron foundries increases the risk of cancer...
  95. ncbi Immunohistochemical p53 expression patterns in sarcomatoid carcinomas of the upper respiratory tract
    M Ali Ansari-Lari
    Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland, U S A
    Am J Surg Pathol 26:1024-31. 2002
    ..Instead, the epithelial and spindled components share a common pathway of tumorigenesis despite their conspicuous divergence at the phenotypic level...
  96. ncbi The most expensive medical conditions in America
    Benjamin G Druss
    Department of Psychiatry, Yale University School of Medicine, USA
    Health Aff (Millwood) 21:105-11. 2002
    ..We use the findings to discuss the role for cost-of-illness and burden-of-disease estimates in setting priorities...
  97. ncbi Imaging of MALT lymphomas
    M Rodallec
    Service de Radiologie, Hopital Saint Louis, AP HP, 1 av Claude Vellefaux, 75475 Paris, France
    Eur Radiol 12:348-56. 2002
    ..The lymphoma is generally of low grade and has indolent course. The aim of this article is to exemplify the most common radiological patterns of MALT lymphoma...
  98. ncbi Cancer mortality in rubber tire workers in Poland
    U Wilczynska
    Department of Occupational and Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland
    Int J Occup Med Environ Health 14:115-25. 2001
    ..Nevertheless, the fact that these observations are in agreement with the findings of other authors who carried out studies in the rubber industry of other countries justifies the need to follow-up this cohort in the future...
  99. ncbi Gender and time differences in initial location and histological grade of non-Hodgkin's lymphomas in Southern Sweden
    L Brandt
    Department of Oncology, Southern Swedish Regional Tumour Registry, University Hospital, Lund
    Acta Oncol 40:479-84. 2001
    ..Epidemiologic studies where both malignancy grade and initial lymphoma locations are taken into account may be helpful in defining risk factors...
  100. ncbi Recurrent respiratory papillomatosis
    C S Derkay
    Department of Otolaryngology and Pediatrics, Eastern Virginia Medical School, Norfolk 23507, USA
    Laryngoscope 111:57-69. 2001
    ..Adjuvant modalities of surgical and nonsurgical treatment and their indications are discussed. Ongoing research initiatives and the Practice Guidelines of the Recurrent Respiratory Papillomatosis Task Force are also included...
  101. ncbi Natural organic fibers--health effects
    B Jarvholm
    Department of Public Health and Clinical Medicine, Umea University, Sweden
    Int Arch Occup Environ Health 73:S69-74. 2000
    ..They are also constituents of food and added to food to promote health. The objective of this review is to evaluate the health effects of natural organic fibers. The health effects of dietary fibers are excluded from the review...

Research Grants20

  1. HPV-Specific, Immune Suppression in Patients with RRP
    VINCENT ROBERT BONAGURA; Fiscal Year: 2010
    ..mild/moderate disease. These studies will identify immune system cells that inappropriately respond to HPV, help develop a therapeutic vaccine, and new strategies to treat patients with RRP. ..
  2. HPV-Specific, Immune Suppression in Patients with RRP
    Vincent Bonagura; Fiscal Year: 2009
    ..mild/moderate disease. These studies will identify immune system cells that inappropriately respond to HPV, help develop a therapeutic vaccine, and new strategies to treat patients with RRP. ..
  3. HPV-Specific, Immune Suppression in Patients with RRP
    Vincent Bonagura; Fiscal Year: 2008
    ..mild/moderate disease. These studies will identify immune system cells that inappropriately respond to HPV, help develop a therapeutic vaccine, and new strategies to treat patients with RRP. ..
  4. HPV-Specific, Immune Suppression in Patients with RRP
    Vincent Bonagura; Fiscal Year: 2007
    ..mild/moderate disease. These studies will identify immune system cells that inappropriately respond to HPV, help develop a therapeutic vaccine, and new strategies to treat patients with RRP. ..
  5. HPV-Specific, Immune Suppression in Patients with RRP
    Vincent Bonagura; Fiscal Year: 2006
    ..mild/moderate disease. These studies will identify immune system cells that inappropriately respond to HPV, help develop a therapeutic vaccine, and new strategies to treat patients with RRP. ..
  6. SURVEILLANCE METHODS FOR HEALTH CARE AND RELATED WORKERS
    John Dement; Fiscal Year: 2003
    ..Results of the case-based surveillance effort also will have broad application to health care workers. ..
  7. SURVEILLANCE METHODS FOR HEALTH CARE AND RELATED WORKERS
    John Dement; Fiscal Year: 2004
    ..Results of the case-based surveillance effort also will have broad application to health care workers. ..
  8. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 2005
    ..abstract_text> ..
  9. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 2006
    ..abstract_text> ..
  10. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 2004
    ..abstract_text> ..
  11. HPV ETIOLOGY OF A SUBSET OF HEAD AND NECK CANCERS
    Keerti Shah; Fiscal Year: 2004
    ..If HPV etiology is established for a subset of HNSCC, patients with these tumors may benefit from HPV-specific immunotherapies which are being evaluated for the treatment of invasive cervical cancer. ..
  12. HPV ETIOLOGY OF A SUBSET OF HEAD AND NECK CANCERS
    Keerti Shah; Fiscal Year: 2000
    ..If HPV etiology is established for a subset of HNSCC, patients with these tumors may benefit from HPV-specific immunotherapies which are being evaluated for the treatment of invasive cervical cancer. ..
  13. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 2000
    ....
  14. SURVEILLANCE METHODS FOR HEALTH CARE AND RELATED WORKERS
    John Dement; Fiscal Year: 2001
    ..Results of the case-based surveillance effort also will have broad application to health care workers. ..
  15. HPV ETIOLOGY OF A SUBSET OF HEAD AND NECK CANCERS
    Keerti Shah; Fiscal Year: 2001
    ..If HPV etiology is established for a subset of HNSCC, patients with these tumors may benefit from HPV-specific immunotherapies which are being evaluated for the treatment of invasive cervical cancer. ..
  16. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 2001
    ....
  17. HPV ETIOLOGY OF A SUBSET OF HEAD AND NECK CANCERS
    Keerti Shah; Fiscal Year: 2002
    ..If HPV etiology is established for a subset of HNSCC, patients with these tumors may benefit from HPV-specific immunotherapies which are being evaluated for the treatment of invasive cervical cancer. ..
  18. SURVEILLANCE METHODS FOR HEALTH CARE AND RELATED WORKERS
    John Dement; Fiscal Year: 2002
    ..Results of the case-based surveillance effort also will have broad application to health care workers. ..
  19. HPV ETIOLOGY OF A SUBSET OF HEAD AND NECK CANCERS
    Keerti Shah; Fiscal Year: 2003
    ..If HPV etiology is established for a subset of HNSCC, patients with these tumors may benefit from HPV-specific immunotherapies which are being evaluated for the treatment of invasive cervical cancer. ..
  20. GENETIC DETERMINANTS OF MULTISTEP ORAL TUMORIGENESIS
    Walter Hittelman; Fiscal Year: 1999
    ....