Genomes and Genes
sleep apnea syndromes
Summary: Disorders characterized by multiple cessations of respirations during sleep that induce partial arousals and interfere with the maintenance of sleep. Sleep apnea syndromes are divided into central (see SLEEP APNEA, CENTRAL), obstructive (see SLEEP APNEA, OBSTRUCTIVE), and mixed central-obstructive types.
Publications266 found, 100 shown here
- Prospective study of the association between sleep-disordered breathing and hypertensionP E Peppard
Department of Preventive Medicine, University of Wisconsin School of Medicine, Madison 53705, USA
N Engl J Med 342:1378-84. 2000....
- A new method for measuring daytime sleepiness: the Epworth sleepiness scaleM W Johns
Sleep Disorders Unit, Epworth Hospital, Melbourne, Victoria, Australia
Sleep 14:540-5. 1991..ESS scores of patients who simply snored did not differ from controls...
- Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health StudyE Shahar
Division of Epidemiology, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
Am J Respir Crit Care Med 163:19-25. 2001..99-1.62), respectively. These findings are compatible with modest to moderate effects of sleep-disordered breathing on heterogeneous manifestations of CVD within a range of AHI values that are considered normal or only mildly elevated...
- Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health StudyNaresh M Punjabi
Division of Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, MD21224, USA
Am J Epidemiol 160:521-30. 2004..The results of this study suggest that SDB is independently associated with glucose intolerance and insulin resistance and may lead to type 2 diabetes mellitus...
- Sleep-disordered breathing and mortality: a prospective cohort studyNaresh M Punjabi
Johns Hopkins University, Baltimore, Maryland, United States of America
PLoS Med 6:e1000132. 2009....
- Sleep apnea and cardiovascular disease: an American Heart Association/american College Of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Virend K Somers
Circulation 118:1080-111. 2008
- Longitudinal study of moderate weight change and sleep-disordered breathingP E Peppard
University of Wisconsin School of Medicine, Department of Preventive Medicine, 502 N Walnut St, Madison, WI 53705, USA
JAMA 284:3015-21. 2000..Excess body weight is positively associated with sleep-disordered breathing (SDB), a prevalent condition in the US general population. No large study has been conducted of the longitudinal association between SDB and change in weight...
- Estimation of the clinically diagnosed proportion of sleep apnea syndrome in middle-aged men and womenT Young
Department of Preventive Medicine, University of Wisconsin-Madison 53705, USA
Sleep 20:705-6. 1997..These findings provide a baseline for assessing health care resource needs for sleep apnea...
- Obstructive sleep apnoea syndrome as a risk factor for hypertension: population studyP Lavie
Sleep Laboratory, Bruce Rappaport Faculty of Medicine, Israel Institute of Technology, Haifa, Israel
BMJ 320:479-82. 2000..To assess whether sleep apnoea syndrome is an independent risk factor for hypertension...
- Sleep. 4: Sleepiness, cognitive function, and quality of life in obstructive sleep apnoea/hypopnoea syndromeH M Engleman
Edinburgh Sleep Centre, Unit of Respiratory Medicine, University of Edinburgh, Lauriston Place, Edinburgh EH3 9YW, Scotland, UK
Thorax 59:618-22. 2004..The evidence is compatible with hypotheses that these deficits are reversible with treatment, particularly for patients with severe disease...
- Practice parameters for the indications for polysomnography and related procedures: an update for 2005Clete A Kushida
Stanford University Center of Excellence for Sleep Disorders, Stanford, CA, USA
Sleep 28:499-521. 2005....
- Incidence of sleep-disordered breathing in an urban adult population: the relative importance of risk factors in the development of sleep-disordered breathingPeter V Tishler
Veterans Affairs Boston Healthcare System and Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Mass 02115, USA
JAMA 289:2230-7. 2003..Sleep-disordered breathing (SDB) is both prevalent and associated with serious chronic illness. The incidence of SDB and the effect of risk factors on this incidence are unknown...
- Sleep-disordered breathing in community-dwelling elderlyS Ancoli-Israel
Department of Psychiatry, University of California, San Diego
Sleep 14:486-95. 1991..Despite statistical significance, all of the associations between interview variables and apnea indices were small. No combination of demographic variables and symptoms allowed highly reliable prediction of AI or RDI...
- The Sleep Heart Health Study: design, rationale, and methodsS F Quan
Department of Medicine and Respiratory Sciences Center, University of Arizona, Tucson 85724, USA
Sleep 20:1077-85. 1997..The study provides sufficient statistical power for assessing OSA and other SDB as risk factors for major cardiovascular events, including myocardial infarction and stroke...
- Current opinions and clinical practice in the titration of oral appliances in the treatment of sleep-disordered breathingMarijke Dieltjens
Clinical Department of Special Care Dentistry, University of Antwerp UA and Antwerp University Hospital UZA, Edegem, Antwerp, Belgium
Sleep Med Rev 16:177-85. 2012..At present, a consensus exists that an optimal titration protocol is of primary importance to achieve a successful treatment outcome with an MRA. To date however, there is no consensus on how to define the optimal titration protocol...
- Longitudinal association of sleep-related breathing disorder and depressionPaul E Peppard
Department of Population Health Sciences, University of Wisconsin Madison, Madison, WI 53706, USA
Arch Intern Med 166:1709-15. 2006..This population-based epidemiological study assesses SRBD as a longitudinal predictor of depression...
- Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular riskNikolaus J Buchner
Department of Internal Medicine I, Marienhospital Herne, Ruhr University Bochum, Hoelkeskampring 40, D 44625 Herne, Germany
Am J Respir Crit Care Med 176:1274-80. 2007..Obstructive sleep apnea (OSA) is linked to increased cardiovascular risk, but the impact of mild forms of OSA and their treatment on cardiovascular outcomes remains controversial...
- Validation of a Chinese version of the Epworth sleepiness scaleNing Hung Chen
Department of Pulmonary and Critical Care Medicine, Sleep Center, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC
Qual Life Res 11:817-21. 2002..The CESS could be used to advantage among other Mandarin-speaking subjects as a standardised screening test of sleepiness in daily life...
- Sleep apnoea in heart failureR Schulz
University of Giessen Lung Center, Klinikstr 36, 35392 Giessen, and Charité University Hospital Berlin, Sleep Disorders Centre, Department of Cardiology Pulmonary Medicine, Germany
Eur Respir J 29:1201-5. 2007..This diagnostic approach should probably be adopted for all of these patients irrespective of the presence of sleep-related symptoms...
- Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapyMarie Marklund
Dept of Orthodontics, Faculty of Medicine, Umea University, Umea, Sweden
Eur Respir J 39:1241-7. 2012..The treatment must be followed up and the device adjusted or exchanged in relation to the outcome...
- Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older womenKristine Yaffe
Department of Psychiatry, University of California, San Francisco, San Francisco, CA 94121, USA
JAMA 306:613-9. 2011..Cross-sectional studies have linked sleep-disordered breathing to poor cognition; however, it remains unclear whether sleep-disordered breathing precedes cognitive impairment in older adults...
- Central cholinergic regulation of respiration: nicotinic receptorsXuesi M Shao
Department of Neurobiology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095 1763, USA
Acta Pharmacol Sin 30:761-70. 2009....
- A controlled study of sleep related disordered breathing in obese childrenY K Wing
Department of Psychiatry, Prince of Wales and Shatin Hospital, Shatin, The Chinese University of Hong Kong, Hong Kong SAR, China
Arch Dis Child 88:1043-7. 2003..Unlike the adult sleep related disordered breathing (SDB) patients who are typically obese, the relation between obesity and childhood SDB is not clear...
- Description and validation of the apnea risk evaluation system: a novel method to diagnose sleep apnea-hypopnea in the homePhilip R Westbrook
Advanced Brain Monitoring, Inc, 2850 Pio Pico Dr, Suite A, Carlsbad, CA 92008, USA
Chest 128:2166-75. 2005..To evaluate the accuracy and practicality of the Apnea Risk Evaluation System (ARES; Advanced Brain Monitoring; Carlsbad, CA), a limited-channel system for diagnosing sleep apnea/hypopnea in the home...
- Mortality in sleep apnea patients: a multivariate analysis of risk factorsP Lavie
Sleep Laboratory and Unit of Pulmonary Diseases, Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa
Sleep 18:149-57. 1995..Age, BMI and hypertension predicted MI deaths in addition to lung disease. These results were interpreted to suggest that SAS affects death indirectly, most probably by being a risk factor for hypertension...
- Is obstructive sleep apnea a problem in Parkinson's disease?Valerie Cochen De Cock
Sleep Disorders Unit, Pitie Salpetriere Hospital, APHP, Paris, France
Sleep Med 11:247-52. 2010..Upper airway dysfunction in PD may promote obstructive sleep apnea. However, the frequency and clinical relevance of sleep-disordered breathing in PD remains unclear...
- Excess weight and sleep-disordered breathingTerry Young
Department of Population Health Sciences, University of Wisconsin Madison, USA
J Appl Physiol (1985) 99:1592-9. 2005..Clearly, if the expanding epidemic of obesity seen in the United States continues, the prevalence of SDB will almost certainly increase, along with the proportion of SDB attributable to obesity...
- Association of sleep-disordered breathing and the occurrence of strokeMichael Arzt
Toronto General Hospital University Health Network, 9N 943, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada
Am J Respir Crit Care Med 172:1447-51. 2005..However, these studies either used surrogate markers of sleep-disordered breathing or could not, due to cross-sectional design, address the temporal relationship between sleep-disordered breathing and stroke...
- Short-term variability of respiration and sleep during unattended nonlaboratory polysomnography--the Sleep Heart Health Study. [corrected]Stuart F Quan
Arizona Respiratory Center and Department of Medicine, University of Arizona College of Medicine, Tucson, AZ 85724, USA
Sleep 25:843-9. 2002..To determine the short-term variability of indices of disturbed respiration and sleep during 2 nights of unattended nonlaboratory polysomnography conducted several months apart...
- Access to diagnosis and treatment of patients with suspected sleep apneaW Ward Flemons
Faculty of Medicine, University of Calgary, Alberta, Canada
Am J Respir Crit Care Med 169:668-72. 2004
- A survey screen for prediction of apneaG Maislin
Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia 19104-4283, USA
Sleep 18:158-66. 1995..79 (p < 0.0001). For BMI alone, it was 0.73, and for an index measuring the self-report of the frequency of apnea symptoms, it was 0.70. The multivariable apnea risk index has potential utility in clinical settings...
- ROS signaling in systemic and cellular responses to chronic intermittent hypoxiaNanduri R Prabhakar
Center for Systems Biology, Department of Medicine, The University of Chicago, Chicago, Illinois 60637, USA
Antioxid Redox Signal 9:1397-403. 2007....
- Sleep apnoea syndrome is highly prevalent in acromegaly and only partially reversible after biochemical control of the diseaseMaria Vittoria Davi'
Clinic of Internal Medicine D, Department of Biomedical and Surgical Sciences, University of Verona, Policlinico GB Rossi, Verona, Italy
Eur J Endocrinol 159:533-40. 2008..Whether sleep apnoea syndrome (SAS) subsides after biochemical and clinical remission of acromegaly is controversial...
- Pregnancy and fetal outcomes of symptoms of sleep-disordered breathingG Bourjeily
Dept of Medicine, Women and Infants Hospital of Rhode Island, 100 Dudley Street, 3rd Floor, Providence, RI 02905, USA
Eur Respir J 36:849-55. 2010..Symptoms of SDB are common in pregnancy and associated with a higher likelihood of gestational hypertensive disorders, gestational diabetes and unplanned Caesarean deliveries...
- Diabetes and sleep disturbances: findings from the Sleep Heart Health StudyHelaine E Resnick
MedStar Research Institute, Hyattsville, Maryland 20783, USA
Diabetes Care 26:702-9. 2003..To test the hypothesis that diabetes is independently associated with sleep-disordered breathing (SDB), and in particular that diabetes is associated with sleep abnormalities of a central, rather than obstructive, nature...
- Marked decrease in sleepiness in patients with sleep apnea by etanercept, a tumor necrosis factor-alpha antagonistA N Vgontzas
Department of Psychiatry H073, Pennsylvania State University College of Medicine, 500 University Drive, Hershey, Pennsylvania 17033, USA
J Clin Endocrinol Metab 89:4409-13. 2004..9 vs. 3.1 min), suggests that proinflammatory cytokines contribute to the pathogenesis of OSA/sleepiness...
- Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-upYuksel Peker
Sleep Laboratory, Department of Pulmonary Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden
Am J Respir Crit Care Med 166:159-65. 2002..Furthermore, efficient treatment of OSA reduces the excess CVD risk and may be considered also in relatively mild OSA without regard to daytime sleepiness...
- Prevalence and types of sleep disturbances acutely after traumatic brain injuryVani Rao
Division of Geriatric Psychiatry and Neuropsychiatry, Department of Psychiatry, Baltimore, MD, USA
Brain Inj 22:381-6. 2008..To assess the prevalence of and risk factors for sleep disturbances in the acute post-traumatic brain injury (TBI) period...
- The significance and outcome of continuous positive airway pressure-related central sleep apnea during split-night sleep studiesTarek Dernaika
University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
Chest 132:81-7. 2007....
- Are sleep problems under-recognised in general practice?S Blunden
University of South Australia, Centre for Sleep Research, 5th Floor, Basil Hetzel Institute, Queen Elizabeth Hospital, Woodville Road, Woodville, SA 5011, Australia
Arch Dis Child 89:708-12. 2004..To evaluate the frequency of sleep problems in Australian children aged 4.5-16.5 years, and to determine whether the frequency of sleep problems on questionnaire predicts the reporting of sleep problems at consultation...
- Titrated mandibular advancement versus positive airway pressure for sleep apnoeaF Gagnadoux
Departement de Pneumologie, CHU, Angers, France
Eur Respir J 34:914-20. 2009..Both treatments improved functional outcomes to a similar degree. One-night titration of MAd had a low negative predictive value for treatment success...
- Health, social and economical consequences of sleep-disordered breathing: a controlled national studyPoul Jennum
Danish Center for Sleep Medicine, Department of Clinical Neurophysiology, Faculty of Health Sciences, University of Copenhagen, Glostrup Hospital, DK 2600 Glostrup, Denmark
Thorax 66:560-6. 2011..The objective direct and indirect costs of sleep-disordered breathing (snoring, sleep apnoea (SA) and obesity hypoventilation syndrome (OHS)) and the treatment are incompletely described...
- The effect of chronic or intermittent hypoxia on cognition in childhood: a review of the evidenceJoel L Bass
Department of Pediatrics, Newton Wellesley Hospital, MassGeneral Hospital for Children, Harvard Medical School, Newton, Massachusetts 02462, USA
Pediatrics 114:805-16. 2004....
- Effects of nasal CPAP treatment on insulin resistance, lipid profile, and plasma leptin in sleep apneaCaglar Cuhadaroglu
Department of Chest Diseases, Istanbul Faculty of Medicine, Istanbul University, Gogus Hastaliklari Anabilim Dali, Istanbul, Turkey
Lung 187:75-81. 2009....
- Effect of transsphenoidal surgery on sleep apnoea in acromegalyLisa Sze
Division of Endocrinology and Diabetes, Department of Internal Medicine, Kantonsspital St Gallen, 9007 St Gallen, Switzerland
Eur J Endocrinol 156:321-9. 2007..The aim of this study was to assess the prevalence and risk factors of SAS in acromegaly and to analyze the effect of transsphenoidal adenomectomy on SAS and cardiovascular risk factors...
- Sleep-related breathing disorders are associated with ventricular arrhythmias in patients with an implantable cardioverter-defibrillatorJoachim Fichter
Department of Internal Medicine V, Universitatskliniken des Saarlandes, Homburg Saar, Germany
Chest 122:558-61. 2002....
- Measuring agreement between diagnostic devicesW Ward Flemons
Faculty of Medicine, University of Calgary, Calgary, AB, Canada
Chest 124:1535-42. 2003..Each approach has advantages and limitations, which are highlighted in this review...
- Effect of nasal continuous positive airway pressure during sleep on 24-hour blood pressure in obstructive sleep apneaI Wilcox
Department of Medicine, University of Sydney, Australia
Sleep 16:539-44. 1993....
- Analysis of the interbeat interval increment to detect obstructive sleep apnoea/hypopnoeaF Roche
Department of Clinical Physiology and Exercise, Faculty of Medicine, Jacques Lisfranc University Jean Monnet, Saint Etienne, France, and Sleep Laboratory, Department of Psychiatry, University Hospital, Geneva, Switzerland
Eur Respir J 29:1206-11. 2007..Higher power spectral density of the interbeat interval increment of very low frequencies may also indicate disrupted sleep in the absence of clear clinical symptoms of sleep apnoea/hypopnoea syndrome...
- Invited review: Physiological consequences of intermittent hypoxia: systemic blood pressureE C Fletcher
Division of Respiratory, Critical Care and Environmental Medicine, University of Louisville School of Medicine, Louisville, Kentucky 40292, USA
J Appl Physiol (1985) 90:1600-5. 2001..It appears that adrenergic and renin-angiotensin system overactivity contributes to the early chronic elevated blood pressure in rat intermittent hypoxia and perhaps to human hypertension associated with obstructive sleep apnea...
- Sleep disordered breathing with excessive daytime sleepiness is a risk factor for mortality in older adultsNalaka S Gooneratne
Division of Geriatric Medicine, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
Sleep 34:435-42. 2011..This study examined the relationship between daytime sleepiness, SDB, self-report sleep parameters, and mortality in older adults...
- Outcome of COPD patients with mild daytime hypoxaemia with or without sleep-related oxygen desaturationA Chaouat
Dept of Pneumology, University Hospital, Strasbourg, France
Eur Respir J 17:848-55. 2001..Such isolated nocturnal hypoxaemia or sleep-related worsening of moderate daytime hypoxaemia does not appear to favour the development of pulmonary hypertension, nor to lead to worsening of daytime blood gases...
- Continuous analysis and monitoring of snores and their relationship to the apnea-hypopnea indexJose Antonio Fiz
Hospital de Navarra, Fundación Miguel Servet, Pamplona, Navarra, Spain
Laryngoscope 120:854-62. 2010....
- Home diagnosis of sleep apnea: a systematic review of the literature. An evidence review cosponsored by the American Academy of Sleep Medicine, the American College of Chest Physicians, and the American Thoracic SocietyW Ward Flemons
Faculty of Medicine, University of Calgary, Calgary, AB, Canada
Chest 124:1543-79. 2003
- Nocturnal haemodialysis increases pharyngeal size in patients with sleep apnoea and end-stage renal diseaseJaime M Beecroft
Department of Medicine, University of Calgary, Alberta, Canada
Nephrol Dial Transplant 23:673-9. 2008..We hypothesized that NHD increases pharyngeal cross-sectional area and that this is associated with an improvement in sleep apnoea...
- Systematic comparison of different algorithms for apnoea detection based on electrocardiogram recordingsT Penzel
Department of Respiratory Critical Care Medicine, Hospital of Philipps University, Marburg, Germany
Med Biol Eng Comput 40:402-7. 2002..Four of these algorithms achieved perfect scores of 100% in the first part of the study, and two achieved an accuracy of over 90% in the second part of the study...
- Green tea catechin polyphenols attenuate behavioral and oxidative responses to intermittent hypoxiaIsabel C Burckhardt
Kosair Children s Hospital Research Institute, University of Louisville, 570 South Preston Street, Suite 204, Louisville, KY 40202, USA
Am J Respir Crit Care Med 177:1135-41. 2008..We hypothesized that green tea catechin polyphenols (GTPs) may attenuate IH-induced neurobehavioral deficits by reducing IH-induced NADPH oxidase expression, lipid peroxidation, and inflammation...
- Sleep-disordered breathing as a risk factor for cerebrovascular disease: a case-control study in patients with transient ischemic attacksNigel McArdle
Department of Medicine, University of Edinburgh, Royal Infirmary, Edinburgh, UK
Stroke 34:2916-21. 2003..We explored this relationship in transient ischemic attack (TIA) patients because they are less likely than stroke patients to have OSAH as a consequence of cerebrovascular disease...
- Health care utilization in males with obstructive sleep apnea syndrome two years after diagnosis and treatmentA Bahammam
Sleep Disorders Centre, St. Boniface General Hospital Research Centre, Department of Medicine, Winnipeg, Manitoba
Sleep 22:740-7. 1999..53+0.14 per patient per year (p=0.034) were significant while in the PNAT group they were not. CONCLUSIONS: Adherence to treatment in patients with OSAS results in a significant reduction in physician claims and hospital stays...
- Prospective study of sleep-disordered breathing and hypertension: the Sleep Heart Health StudyGEORGE T O'CONNOR
Pulmonary Center, Boston University School of Medicine, 715 Albany St, Boston, MA 02118, USA
Am J Respir Crit Care Med 179:1159-64. 2009..Cross-sectional epidemiologic studies show an association between sleep-disordered breathing and hypertension, but only one cohort study has examined sleep-disordered breathing as a risk factor for incident hypertension...
- Prevalence of symptoms and risk of sleep apnea in primary careNikolaus C Netzer
The Center for Sleep Disorders Research, Case Western Reserve University, Cleveland, OH, USA
Chest 124:1406-14. 2003..To obtain prevalence estimates for key symptoms and features that can indicate the presence of obstructive sleep apnea (OSA) in a broad range of primary care settings...
- Sleep-disordered breathing occurs frequently in stable outpatients with congestive heart failureKatherine Ferrier
WellSleep, Department of Medicine, Wellington School of Medicine and Health Sciences, New Zealand
Chest 128:2116-22. 2005..The prevalence, type, and severity of SDB in unselected stable outpatients with CHF are unknown...
- Alterations in Glucose Disposal in Sleep-disordered BreathingNaresh M Punjabi
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Am J Respir Crit Care Med 179:235-40. 2009..However, data on whether SDB alters in vivo kinetics of glucose and insulin are lacking...
- Adaptive servoventilation improves cardiac function in patients with chronic heart failure and Cheyne-Stokes respirationOlaf Oldenburg
Department of Cardiology, Heart and Diabetes Centre North Rhine Westphalia, Ruhr University Bochum, Bad Oeynhausen, Germany
Eur J Heart Fail 10:581-6. 2008..Adaptive servoventilation (ASV) was recently introduced to treat CSR in CHF. The aim of this study was to investigate the effects of ASV on CSR and CHF parameters...
- Daytime sleepiness and hyperactivity in children with suspected sleep-disordered breathingMa Cecilia S Melendres
Eudowood Division of Pediatric Respiratory Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Pediatrics 114:768-75. 2004..Furthermore, we hypothesized that overnight polysomnographic parameters correlated with sleepiness and hyperactivity...
- Effect of nocturnal nasal continuous positive airway pressure on blood pressure in obstructive sleep apneaLydia A Bazzano
Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA
Hypertension 50:417-23. 2007..38 to -0.05). Net reductions in blood pressure were not statistically different between daytime and nighttime. These results indicate that CPAP decreases blood pressure among those with OSA and may help prevent hypertension...
- Positive effect of CPAP treatment on the control of difficult-to-treat hypertensionM A Martínez-García
Pneumology Unit, Requena General Hospital, Valencia, Spain
Eur Respir J 29:951-7. 2007..Continuous positive airway pressure treatment significantly reduces systolic blood pressure, particularly at night, and normalises the nocturnal pressure pattern in patients with difficult-to-control hypertension and sleep apnoea...
- Endogenous excitatory drive modulating respiratory muscle activity across sleep-wake statesErin Chan
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Respir Crit Care Med 174:1264-73. 2006..However, a neurotransmitter substrate mediating respiratory muscle activation across sleep-wake states has not been identified...
- Hypothalamic-pituitary-adrenal axis activation in obstructive sleep apnea: the effect of continuous positive airway pressure therapyDavid E Henley
Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, University of Bristol, Bristol BS1 3NY, United Kingdom
J Clin Endocrinol Metab 94:4234-42. 2009..We hypothesized that these may result from OSA-induced perturbations of endogenous ultradian hypothalamic-pituitary-adrenal axis activity...
- Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep durationEmma K Larkin
Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Triangle Building Suite 260, 10400 Euclid Ave, Cleveland, OH 44106, USA
Circulation 111:1978-84. 2005..The goal of this study was to quantify the associations of SDB, sleep duration, and CRP in adolescents to better understand the role of SDB in CVD risk...
- Spectral oscillations of RR intervals in sleep apnoea/hypopnoea syndrome patientsK Dingli
Respiratory Medicine, University of Edinburgh, Edinburgh, UK
Eur Respir J 22:943-50. 2003..The recurrent nocturnal fluctuations of sympathovagal balance and the overall increase of nocturnal autonomic activity may be of importance in the development of cardiovascular disease in sleep apnoea patients...
- A mediation model linking body weight, cognition, and sleep-disordered breathingKaren Spruyt
Department of Pediatrics, Pritzker School of Medicine, The University of Chicago, IL 60637, USA
Am J Respir Crit Care Med 185:199-205. 2012....
- Neurobehavioral morbidity associated with disordered breathing during sleep in children: a comprehensive reviewDean W Beebe
Cincinnati Children s Hospital Medical Center, Department of Pediatrics, University of Cincinnati School of Medicine, Cincinnati, OH 45229, USA
Sleep 29:1115-34. 2006..To comprehensively review research on the association between childhood sleep-disordered breathing (SDB) and neurobehavioral functioning...
- A controlled trial of CPAP therapy on metabolic control in individuals with impaired glucose tolerance and sleep apneaTanya G Weinstock
Department of Medicine, Brigham and Women s Hospital and Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
Sleep 35:617-625B. 2012..To address whether treatment of sleep apnea improves glucose tolerance...
- Daytime Cheyne-Stokes respiration in ambulatory patients with severe congestive heart failure is associated with increased mortalityThomas Brack
Division of Pulmonary Medicine, University Hospital Zurich, Switzerland
Chest 132:1463-71. 2007..Daytime CSR supposedly poses an even greater risk, but its prevalence and prognostic importance remain elusive. Therefore, we investigated the circadian prevalence of CSR and its influence on survival in patients with heart failure...
- Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemiaA N Vgontzas
Sleep Research and Treatment Center, Department of Psychiatry, Pennsylvania State University, Hershey 17033, USA
J Clin Endocrinol Metab 85:1151-8. 2000..We conclude that there is a strong independent association among sleep apnea, visceral obesity, insulin resistance and hypercytokinemia, which may contribute to the pathological manifestations and somatic sequelae of this condition...
- Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneasYing Jie Peng
Department of Physiology and Biophysics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA
Proc Natl Acad Sci U S A 100:10073-8. 2003..The sensory LTF may contribute to persistent reflex activation of sympathetic nerve activity and blood pressure in recurrent apnea patients experiencing CIH...
- Sleep apnea in early and advanced chronic kidney disease: Kaiser Permanente Southern California cohortJohn J Sim
Division of Nephrology and Hypertension, Kaiser Permanente Los Angeles Medical Center, 4700 Sunset Blvd, Los Angeles, CA 90027, USA
Chest 135:710-6. 2009..This study sought to determine whether an association exists between SA and early stages of chronic kidney disease (CKD) where SA may represent an important comorbidity and potential risk factor in kidney disease...
- Sleep in overweight adolescents: shorter sleep, poorer sleep quality, sleepiness, and sleep-disordered breathingDean W Beebe
Division of Behavioral Medicine and Clinical Psychology MLC 3015, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, Ohio 45229, USA
J Pediatr Psychol 32:69-79. 2007..To document the sleep of overweight adolescents and to explore the degree to which weight-related sleep pathology might account for diminished psychosocial outcome...
- Variation in symptoms of sleep-disordered breathing with race and ethnicity: the Sleep Heart Health StudyGEORGE T O'CONNOR
Department of Medicine, Boston University School of Medicine, Boston, MA 02118 2394, USA
Sleep 26:74-9. 2003..To examine the relation of sleep-related symptoms to race and ethnicity in a diverse sample of middle-aged and older men and women...
- Heart failure and sleep apnoea: to sleep perchance to dreamSusana Ferreira
Faculdade Medicina do Porto, Portugal
Eur J Heart Fail 8:227-36. 2006....
- High prevalence of unrecognized sleep apnoea in drug-resistant hypertensionA G Logan
Samuel Lunenfeld Research Institute, Mount Sinai Hospital, and University of Toronto, Toronto, Ontario, Canada
J Hypertens 19:2271-7. 2001..To determine the prevalence of obstructive sleep apnoea (OSA) in adult patients with drug-resistant hypertension, a common problem in a tertiary care facility...
- Snoring in preschool children: prevalence, severity and risk factorsC E Kuehni
Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland
Eur Respir J 31:326-33. 2008..The strong association with atopic disorders, viral infections and environmental exposures suggests a complex aetiology, based on a general vulnerability of the respiratory tract...
- Con: Sleep apnea does not cause cardiovascular diseaseJohn Stradling
Am J Respir Crit Care Med 169:148-9; discussion 150. 2004
- The nose and sleep-disordered breathing: what we know and what we do not knowMaria Rappai
Division of Pulmonary Critical Care Medicine, University of Mississippi Medical Center, Jackson, MS, USA
Chest 124:2309-23. 2003..We postulate that the switch to oronasal breathing that occurs with chronic nasal conditions is a final common pathway for SDB...
- Bi-level positive pressure ventilation and adaptive servo ventilation in patients with heart failure and Cheyne-Stokes respirationIngo Fietze
Charite Universitatsmedizin Berlin, CCM, Department of Internal Medicine, Center for Sleep Medicine, Luisenstr 13, D 10117 Berlin, Germany
Sleep Med 9:652-9. 2008..We investigated the effect of a bi-level PPV and adaptive servo ventilation on LVEF, CSR, and quantitative sleep quality...
- Sleep-disordered breathing: a risk factor for adverse pregnancy outcomes?Francesca L Facco
Department of Obstetrics and Gynecology, Northwestern University, Chicago, Illinois, USA
Am J Perinatol 29:277-82. 2012..7%. SDB, especially moderate to severe disease, may be associated with APO. However, it is unclear if SDB is a risk factor for APO independent of obesity...
- Sleep-disordered breathing in obese children: the southern Italy experienceLuigia Brunetti
Clinica Pediatrica S Maggiore, Policlinico, University of Bari, Piazza Giulio Cesare, 11 70124 Bari, Italy
Chest 137:1085-90. 2010..We sought an association between sleep-disordered breathing (SDB) and overweight and/or obesity in a large cohort of school- and preschool-aged children in Southern Italy...
- A simple method to identify sleep apnea using Holter recordingsPhyllis K Stein
Cardiovascular Division, Washington University School of Medicine, St Louis, Missouri 63108, USA
J Cardiovasc Electrophysiol 14:467-73. 2003....
- Long-term nasal continuous positive airway pressure administration can normalize hypertension in obstructive sleep apnea patientsM Suzuki
Stanford University Sleep Disorders Clinic and Research Center, California 94304
Sleep 16:545-9. 1993..Average HR during the day and at night decreased significantly from 85.2 bpm to 72.6 bpm and from 69.8 bpm to 56.5 bpm in the hypertensives (p = 0.04), but not in normotensives.(ABSTRACT TRUNCATED AT 250 WORDS)..
- The prevalence of sleepiness and the risk of sleep-disordered breathing in children with positive allergy testStacey L Ishman
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, USA
Int Forum Allergy Rhinol 2:139-43. 2012..We evaluated the prevalence of sleep-disordered breathing (SDB) and sleepiness in children with allergy and compared sleep-specific quality of life measures to those of children without allergy...
- Reactive oxygen species and the brain in sleep apneaYang Wang
Section of Pediatric Sleep Medicine, Department of Pediatrics, Comer Children s Hospital, The University of Chicago, Chicago, IL 60637, USA
Respir Physiol Neurobiol 174:307-16. 2010..The initial evidence for NADPH oxidase and mitochondrial involvement in IH-induced ROS production and neuronal injury unquestionably warrants future research efforts...
- Cross-correlation of EEG frequency bands and heart rate variability for sleep apnoea classificationHaslaile Abdullah
School of Electrical and Computer Engineering, Science, Engineering and Health, RMIT University, 376 392 Swanston Street, GPO Box 2476V, Melbourne, Vic, 3001, Australia
Med Biol Eng Comput 48:1261-9. 2010..When delta and acceleration coefficients of the EEG features were incorporated, then the overall accuracy improved to 71%...
- Familial risk of sleep-disordered breathingKarin Lundkvist
Department of Otorhinolaryngology, Karolinska Institutet, Stockholm, Sweden
Sleep Med 13:668-73. 2012....
- New tracheal sound feature for apnoea analysisA Kulkas
Department of Clinical Neurophysiology, Medical Imaging Center, Pirkanmaa Hospital District, Tampere, Finland
Med Biol Eng Comput 47:405-12. 2009..8%. Due to the individual differences in tracheal sound signal amplitudes, developing amplitude-independent means for screening apnoea events is beneficial...
- Reliability and validity studies of the Turkish version of the Epworth Sleepiness ScaleBilgay Izci
Department of Sleep Medicine, University of Edinburgh, 51 Little France Crescent, Edinburgh EH16 4SA, Scotland, UK
Sleep Breath 12:161-8. 2008..The ESStr is a reliable and valid measure of daytime sleepiness. These features and the simplicity of the ESStr make it a valuable measure for clinical management and research...
- Automatic breath-to-breath analysis of nocturnal polysomnographic recordingsP J van Houdt
Department of Research and Development, Kempenhaeghe, Postbus 61, 5590 AB, Heeze, The Netherlands
Med Biol Eng Comput 49:819-30. 2011....
- Children's sleep and adjustment over time: the role of socioeconomic contextMona El-Sheikh
Human Development and Family Studies, 203Spidle Hall, Auburn University, Auburn, AL 36849 5214, USA
Child Dev 81:870-83. 2010..Findings highlight the importance of adequate sleep for children's optimal development, especially in the context of ecological risk...
- Neurobehavioral manifestations in obstructive sleep apnea syndrome before and after treatment with continuous positive airway pressureJ Montplaisir
, , , Canada
Sleep 15:S17-9. 1992..After treatment, hypoxemia-related deficits and some degree of sleepiness persist. These results raise the possibility of an irreversible anoxic central nervous system (CNS) damage in severe OSAS...
- High fat/refined carbohydrate diet enhances the susceptibility to spatial learning deficits in rats exposed to intermittent hypoxiaA D Goldbart
Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA
Brain Res 1090:190-6. 2006..high fat refined carbohydrate diet (HF/RC) can induce similar deficits and associated changes in signaling pathways under normoxic conditions...
- Impaired spatial working memory and altered choline acetyltransferase (CHAT) immunoreactivity and nicotinic receptor binding in rats exposed to intermittent hypoxia during sleepBarry W Row
Kosair Children s Hospital Research Institute, Department of Pediatrics, University of Louisville, Louisville, KY 40202, USA
Behav Brain Res 177:308-14. 2007..However, compensatory mechanisms may also be activated in other brain regions, and may provide potential therapeutic targets for the cognitive impairments associated with SDB...
- Treatment of Sleep Apnea using a Positive Airway Pressure Rebreathing ModulatorMatthew D Tarler; Fiscal Year: 2011..of positive airway pressure therapies is an important stabilizing factor for chemoreflex-modulated sleep apnea syndromes. The Positive Airway Pressure Gas Modulator (PAPGAM), a new class of positive airway pressure device ..
- Stimulation Induced Modulation of SleepMATTHEW TARLER; Fiscal Year: 2009..chemoreflexes can contribute to the severity of sleep apnea, and the development of hypertension in sleep apnea syndromes. In congestive heart failure, augmented carotid chemoreflexes contributes to the increased sympathetic ..
- Effects of aging on sleep architectureNaresh Punjabi; Fiscal Year: 2006..unreadable] [unreadable]..
- EARLY IDENTIFICATION AND TREATMENT OF SLEEP APNEANaresh Punjabi; Fiscal Year: 2003..Punjabi the opportunity to reach his full potential as a clinical investigator. ..
- THE SLEEP HEART HEALTH STUDYNaresh Punjabi; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
- Longtitudinal Changes in Sleep Structure: Implications for Health OutcomesNaresh Punjabi; Fiscal Year: 2010....
- WORKING MEMORY IN OBSTRUCTIVE SLEEP APNEA-AN fMRI STUDYRobert Thomas; Fiscal Year: 2006..abstract_text> ..
- ECG-derived estimators of sleep physiologyRobert Thomas; Fiscal Year: 2006..3) To correlate the biomarker with excessive daytime sleepiness, subjective sleep quality and cardiovascular morbidity (SHHS), and reduced neurocognitive function (NAPS). ..
- THE ROLE OF CYTOKINES IN SLEEPINESS AND SLEEP APNEAAlexandros Vgontzas; Fiscal Year: 2009..These studies collectively will provide additional evidence for a role of TNFa and IL-6 in EDS and OSA and lay the foundation for the development of novel therapeutic interventions. ..
- NEURAL CONTROL OF CARDIORESPIRATORY FUNCTIONRonald Harper; Fiscal Year: 2004....
- Melatonin Randomized Trial in Insomnia in the ElderlyNalaka Gooneratne; Fiscal Year: 2006..abstract_text> ..
- PHYSIOLOGICAL DEVELOPMENT IN SIDSRonald Harper; Fiscal Year: 2009..Since SIDS may result from hypotension or failure to enhance breathing to hypoxia, the studies may describe mechanisms of failure in the syndrome. ..
- ROLE OF MELATONIN IN SECONDARY INSOMNIA IN THE ELDERLYNalaka Gooneratne; Fiscal Year: 2004....
- Snoring, Early Behavior, and Oxidant StressHAWLEY MONTGOMERY DOWNS; Fiscal Year: 2004..In addition, it may provide insights into a potential mechanism for this morbidity. ..
- Biomarkers of Aging in the Bay Area Sleep CohortDonald Bliwise; Fiscal Year: 2005..abstract_text> ..
- Postpartum Sleep Deprivation and Fragmentation: Effects on Maternal FunctioningHAWLEY MONTGOMERY DOWNS; Fiscal Year: 2008..The study results will help researchers develop better strategies for improving the sleep of new mothers, and in turn improving their ability to function effectively. [unreadable] [unreadable] [unreadable]..
- Polysomnographic Assessment of Alternative TreatmentDonald Bliwise; Fiscal Year: 2006..abstract_text> ..
- Sleep/Wake Contiuum in Lewy Body DiseaseDonald L Bliwise; Fiscal Year: 2010..The proposed work will also provide important clinical insights into disease correlates and disease course across the broad spectrum of Parkinsonism. ..
- SUNDOWN SYNDROME IN A SKILLED NURSING FACILITYDonald Bliwise; Fiscal Year: 2002..These results will provide information on the mechanistic basis for sundowning in aged patients with dementing disorders. ..
- CAUSES OF SLEEP-INDUCED BREATHING INSTABILITIESJerome Dempsey; Fiscal Year: 2002..These latter studies conduced in sleep are important to testing the sensitivity of respiratory control mechanisms to mechanical feedback-a problem which remains relatively unexplored, especially in the human. ..
- Obstructive Sleep Apnea (OSA) in obese teens & preteens: Neurobahavioral effectsDean Beebe; Fiscal Year: 2008..abstract_text> ..
- Family Linkage Study of Obstructive Sleep ApneaAllan Pack; Fiscal Year: 2007..abstract_text> ..
- CASE CONTROL STUDY OF INSOMNIA IN NONDEPRESSED ELDERLYAllan Pack; Fiscal Year: 2001....
- SDB, metabolic syndrome, and vascular functionF Nieto; Fiscal Year: 2006..abstract_text> ..
- Sleep and Functional Performance in Heart FailureNancy Redeker; Fiscal Year: 2006..SEM will be used to evaluate the factor structure of the sleep disturbance construct and serve as a tool to explore the direct and indirect pathways linking the major study variables. ..
- FATIGUE, SLEEP AND CIRCADIAN RHYTHMS IN BREAST CANCERSonia Ancoli Israel; Fiscal Year: 2004..Results will provide a scientific basis for future intervention studies, particularly studies with light therapy which can re-synchronize rhythms. ..
- Cognitive Behavioral Therapy for Insomnia in Stable Heart FailureNancy S Redeker; Fiscal Year: 2010..We plan to test the effects of cognitive behavioral therapy, on sleep, daytime symptoms, and function middle-aged and older adults who have heart failure. ..
- Contributions of sleep/rhythms/fatigue to "chemobrain"Sonia Ancoli Israel; Fiscal Year: 2009..The reported phenomena of chemobrain will be examined to see if it is related to the complaint of fatigue or sleep disruptions, both of which are known to contribute to decreases in cognitive functioning. ..
- TREATMENT OF SLEEP APNEA IN THE ELDERLYAllan Pack; Fiscal Year: 2003..These data will give novel definitive information both about identification and treatment of sleep apnea in the elderly. ..
- MICROARRAY EXPRESSION PROFILING OF RODENT MODELS OF HUMAAllan Pack; Fiscal Year: 2003..abstract_text> ..
- Mechanisms of Sleep-Disordered Breathing in the Menopausal TransitionGrace W Pien; Fiscal Year: 2010..These findings will allow us to identify women at risk for sleep-disordered breathing after menopause and to focus on tailoring treatments in this area. ..
- Impact of intermittent hypoxia on ventilatory drive and apnea severityJASON HAROLD MATEIKA; Fiscal Year: 2010..This treatment could be particularly useful in individuals who suffer from mild or moderate forms of OSA when used in conjunction with other potential innovative therapies. ..
- PREDOCTORAL TRAINING PROGRAM IN NEUROSCIENCERALPH FREGOSI; Fiscal Year: 2008..Facilities for research training include the extensive equipment and expertise in individual faculty laboratories, as well as comprehensive shared resources at the University of Arizona. ..
- Genetic Mechanisms for Central ApneasKingman Strohl; Fiscal Year: 2007..A genomic approach to recurrent central apneas might provide pathogenic insight relevant to primary sleep apnea syndromes and neurological conditions associated with recurrent apneas and unstable breathing...
- Vascular Functions in Children with Sleep Disorder BreathingRaouf S Amin; Fiscal Year: 2010....
- Adolescent Self-Management of Diabetes: An InterventionShelagh Mulvaney; Fiscal Year: 2007..A larger study will allow for reliable estimates of efficacy for clinical outcomes such as HbA1c, and will allow subgroup analyses with ethnicity, gender, and SES. [unreadable] [unreadable] [unreadable]..
- Sleep-Health & Knowledge in U.S. HispanicsJOSE LOREDO; Fiscal Year: 2009..S. Mexican-American Hispanics should include intensive focus on Sleep Health and Sleep Health knowledge deficits. Key Words: Sleep disorders;Minority health;Epidemiology. ..
- The Sleep Heart Health Study (SHHS)STUART QUAN; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. [unreadable] [unreadable]..
- Technological Home Care: Improving CaregivingCarol Smith; Fiscal Year: 2009..The potential significance and the long term goals are to strengthen home caregiving skills, improve health status, quality of life and self-management of chronic illness symptoms and invasive home care treatment. ..
- Consequences of Neonatal HypoxiaNanduri Prabhakar; Fiscal Year: 2009..Understanding the consequences of neonatal IH provide insights into how neonatal intermittent hypoxia caused by recurrent apneas affects the ventilation in premature infants. Experimental Animal Model: Rat Pups. ..
- Cardiovascular Disease (C/V) in Children with Obstructive Sleep Apnea (OSA)Raouf Amin; Fiscal Year: 2007..unreadable] [unreadable]..
- Intertrigeminal region control of apneaMiodrag Radulovacki; Fiscal Year: 2007..abstract_text> ..
- P20-Mediated Suppression of Vascular ForceChristopher Rembold; Fiscal Year: 2004..Many current treatments target smooth muscle to reduce tone. It is possible that targeting the force suppression pathway (i.e. p20) might provide comparable benefits. ..
- NO-CGMP INHIBITION OF UROGENITAL SMOOTH MUSCLEChristopher Rembold; Fiscal Year: 2004....
- CHEMORECEPTORS AND HYPERTENSION AND SLEEP APNEAJOSE LOREDO; Fiscal Year: 2003..This training will provide the basis of an MPH degree and a solid theoretical background for future conduct of quality clinical research. ..
- GENE REGULATION DURING INTERMITTENT HYPOXIANanduri Prabhakar; Fiscal Year: 2003....
- PUPILLOMETRIC SLEEPINESS IN TREATED SLEEP DISORDERSJoan Shaver; Fiscal Year: 2003..Results will provide evidence about the PUI as a reliable and valid objective outcome measure of waking tendency among controls, and pre-post-treatment for OSA and narcolepsy subjects. ..
- NEUROMUSCULAR CONTROL OF THE PHARYNGEAL AIRWAYRALPH FREGOSI; Fiscal Year: 2002..These experiments will lay the foundation for new and improved treatment strategies for persons with obstructive sleep apnea or with other conditions that are caused by malfunction of the tongue motor system. ..
- SLEEP AND ENTERTAIMENT OF SCN FUNCTIONKingman Strohl; Fiscal Year: 2002..abstract_text> ..
- MN REGIONAL SLEEP DISORDERS CENTER SLEEP ACADEMIC AWARDGerald Rosen; Fiscal Year: 2002....
- SLEEP ACADEMIC AWARD--RECOGNITION OF SLEEP DISORDERSKingman Strohl; Fiscal Year: 2002..We will disseminate of educational assessments, patient-oriented material, and clinical pathways through local and national consultants in both the public and private sector, as well as through interaction with other awardees. ..
- GENETIC DISSECTION OF VENTILATORY TRAITSKingman Strohl; Fiscal Year: 2001..Results will be relevant to illnesses known to result from, or be exacerbated by, poor or excessive ventilatory responses to environmental and pathophysiologic stresses. ..
- RURAL DWELLING OLDER ADULTS: CPAP ADHERENCE SUPPORTCarol Smith; Fiscal Year: 2004..abstract_text> ..
- A Wireless, Multi-Channel Telemetric Biosensor for Research in Animal ModelsKingman Strohl; Fiscal Year: 2006..The proposed research will facilitate animal studies that may lead to a better understanding of sleep disorders and potentially new interventions. [unreadable] [unreadable] [unreadable]..
- HEART RATE VARIABILITY IN SLEEP-DISORDERED BREATHINGMICHAEL KHOO; Fiscal Year: 2005....
- Longitudinal Study--Sleep-Disordered Breathing/PregnancyGrace Pien; Fiscal Year: 2006....
- MENOPAUSE AND MIDLIFE AGING EFFECTS ON SLEEP DISORDERSTerry Young; Fiscal Year: 2006....
- PREVALENCE OF SLEEP DISORDERED BREATHING IN CHILDRENEdward Bixler; Fiscal Year: 2005..The parents of this group will be interviewed for the family history of risk factors associated with SDB in children. This strategy will yield adequate power to establish the prevalence and clinical significance of SDB in children. ..
- PERIPHERAL CHEMORECEPTORS: MECHANISMS & MODULATIONSSukhamay Lahiri; Fiscal Year: 2003..The aim of this proposal is to understand how the processes are initiated in the chemosensory cells. ..
- Nicotine induced neuroplasticity in the carotid bodyEstelle Gauda; Fiscal Year: 2004....
- SLEEP HEART HEALTH STUDYGEORGE O CONNOR; Fiscal Year: 2007..Accomplishing these goals will provide important information concerning the public health impact of SDB. ..
- Sleep and Nocturnal Endocrine Function in MDMA UserUna McCann; Fiscal Year: 2007..Results from the proposed studies will help better define the functional consequences of MDMA exposure in humans, and could shed light on the roles of 5-HT and DA in sleep and nocturnal endocrine function. ..
- Impact of CPAP on Functional Outcomes in Milder OSATerri Weaver; Fiscal Year: 2006..Secondary aims of the study are: 1) to examine whether CPAP also improves daytime sleepiness; 2) to determine whether CPAP can reduce nocturnal blood pressure to lower the risk for stroke and hypertension linked to OSA. ..
- Exploration of ETS Effects on Child Behavior and SleepKimberly Yolton; Fiscal Year: 2005..abstract_text> ..
- MCI, APOE and Sleep Apnea: Effects on CognitionRUTH O HARA; Fiscal Year: 2009..Reducing cognitive impairment and delaying the onset of AD has significant clinical and economic benefits. Thus, the answer to this question could significantly enhance our therapeutic approach to cognitive impairment in older adults. ..