- Swimming-induced pulmonary edema in triathletes
Charles C Miller
Department of Biomedical Sciences, Texas Tech University Health Sciences Center at El Paso Paul L Foster School of Medicine, El Paso, TX 79905, USA
Am J Emerg Med 28:941-6. 2010
b>Pulmonary edema related to water immersion has been reported in military trainees and scuba and breath-hold divers, but rarely in the community. To date, no risk factors for this phenomenon have been identified by epidemiological methods...
- Pathogenesis of enterovirus 71 brainstem encephalitis in pediatric patients: roles of cytokines and cellular immune activation in patients with pulmonary edema
Shih Min Wang
Department of Emergency Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
J Infect Dis 188:564-70. 2003
..epidemics of enterovirus 71 (EV71) infections, which were associated with brainstem encephalitis (BE) and pulmonary edema (PE)...
- Essential roles of sphingosine-1-phosphate receptor 2 in human mast cell activation, anaphylaxis, and pulmonary edema
Carole A Oskeritzian
Department of Biochemistry and Molecular Biology, Virginia Commonwealth University School of Medicine, Richmond, VA 23298, USA
J Exp Med 207:465-74. 2010
..E-triggered anaphylactic responses, including elevation of circulating histamine and associated pulmonary edema in mice, were significantly attenuated by the S1P(2) antagonist JTE-013 and in S1P(2)-deficient mice, in ..
- Lung epithelial fluid transport and the resolution of pulmonary edema
Michael A Matthay
Cardiovascular Research Institute and Department of Medicine, University of California, San Francisco, California 94143 0624, USA
Physiol Rev 82:569-600. 2002
..at the time of birth as well as in the mature lung when pathological conditions lead to the development of pulmonary edema. Currently, the best described molecular transporters are the epithelial sodium channel, the cystic fibrosis ..
- Lung overexpression of the vascular endothelial growth factor gene induces pulmonary edema
R J Kaner
Division of Pulmonary and Critical Care Medicine and Weill Medical College of Cornell University, New York, New York, USA
Am J Respir Cell Mol Biol 22:657-64. 2000
..an identical adenovirus vector with an irrelevant transgene had no effect upon subsequent AdVEGF165-induced pulmonary edema. Together, these data suggest that overexpression of VEGF in the lung may be one mechanism of increased ..
- Extravascular lung water indexed to predicted body weight is a novel predictor of intensive care unit mortality in patients with acute lung injury
Thelma R Craig
Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, UK
Crit Care Med 38:114-20. 2010
Acute lung injury and the acute respiratory distress syndrome are characterized by noncardiogenic pulmonary edema, which can be assessed by measurement of extravascular lung water...
- Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells
Department of Pharmacology and Center for Lung and Vascular Biology, College of Medicine, University of Illinois, Chicago, IL 60612, USA
Circ Res 103:1164-72. 2008
..In contrast to wild-type mice, Sphk1(-/-) mice showed markedly enhanced pulmonary edema formation in response to lipopolysaccharide and PAR-1 activation...
- High-altitude pulmonary edema
Norbert F Voelkel
University of Colorado Health Sciences Center, Denver, CO 80262, USA
N Engl J Med 346:1606-7. 2002
- Predictors of the first heart failure hospitalization in patients who are stable survivors of myocardial infarction complicated by pulmonary congestion and/or left ventricular dysfunction: a VALIANT study
Eldrin F Lewis
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
Eur Heart J 29:748-56. 2008
..We sought to assess the incidence of and prognostic factors for heart failure (HF) hospitalization among survivors of high-risk acute myocardial infarction (MI)...
- Modulation of cytokine production by intravenous immunoglobulin in patients with enterovirus 71-associated brainstem encephalitis
Shih Min Wang
Department of Emergency Medicine, National Cheng Kung University and Hospital, 138 Sheng Li Road, 70428 Tainan, Taiwan
J Clin Virol 37:47-52. 2006
..Several epidemics of enterovirus 71 (EV71) infections occurred in Taiwan since 1998...
- Role of oxidative stress and NFkB in hypoxia-induced pulmonary edema
Department of Experimental Biology, Defense Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi 54, India
Exp Biol Med (Maywood) 233:1088-98. 2008
..increased oxidative stress further upregulates the nuclear transcription factor (NFkB) in the development of pulmonary edema. The rats were exposed to hypobaric hypoxia at 7620 m (280 mm Hg) for different durations, that is, 3 hrs, 6 ..
- The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome
Department of Internal Medicine, University Hospital of Geneva, Switzerland
Crit Care Med 27:304-12. 1999
..the concentrations of proinflammatory mediators, collagenases, and procollagen type III peptides in undiluted pulmonary edema fluids and in plasma obtained in patients with early acute respiratory distress syndrome (ARDS) and in ..
- Saturated hydrogen saline protects the lung against oxygen toxicity
Department of Diving Medicine, Faculty of Naval Medicine, Second Military Medical University, Shanghai, China
Undersea Hyperb Med 37:185-92. 2010
..These results demonstrated that saturated hydrogen saline alleviated hyperoxia-induced pulmonary injury, which was partly responsible for the inhibition of oxidative damage...
- Hypoxia impairs systemic endothelial function in individuals prone to high-altitude pulmonary edema
Marc M Berger
Department of Internal Medicine VI Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Germany
Am J Respir Crit Care Med 172:763-7. 2005
High-altitude pulmonary edema (HAPE) is characterized by excessive pulmonary vasoconstriction and is associated with decreased concentrations of nitric oxide (NO) in the lung...
- Pathophysiology of acute lung injury and the acute respiratory distress syndrome
Lorraine B Ware
Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
Semin Respir Crit Care Med 27:337-49. 2006
..Future therapies aimed at restoring the overall balance of cytokines, oxidants, coagulants, and proteases may ultimately be successful where therapies that target individual cytokines or other mediators have not...
- Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management
Michael A Matthay
Department of Medicine, Cardiovascular Research and Training Institute, University of California at San Francisco, San Francisco, California 94143 0130, USA
Am J Respir Cell Mol Biol 33:319-27. 2005
- Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
Jae W Lee
Department of Anesthesiology, University of California, San Francisco, CA 94143, USA
Proc Natl Acad Sci U S A 106:16357-62. 2009
..coli endotoxin. Intra-bronchial instillation of endotoxin into the distal airspaces resulted in pulmonary edema with the loss of alveolar epithelial fluid transport measured as alveolar fluid clearance...
- Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury
Daniel F McAuley
Cardiovascular Research Institute, University of California, San Francisco, CA, USA
Crit Care Med 32:1470-6. 2004
..clinically relevant airspace concentrations of beta2-adrenergic agonists stimulated maximal alveolar fluid clearance rates and to determine whether beta2 agonist therapy decreased pulmonary edema in experimental acute lung injury.
- Reexpansion pulmonary edema
Department of Surgery, Faculty of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
Ann Thorac Cardiovasc Surg 14:205-9. 2008
When a rapidly reexpanding lung has been in a state of collapse for more than several days, pulmonary edema sometimes occurs in it. This is called reexpansion pulmonary edema (RPE)...
- Alveolar edema fluid clearance and acute lung injury
Département de médecine et Centre de recherche du Centre Hospitalier de l Université de Montréal, Universite de Montreal, Montreal, Quebec, Canada
Respir Physiol Neurobiol 159:350-9. 2007
- Endothelial pathomechanisms in acute lung injury
Nikolaos A Maniatis
M Simou Laboratory, University of Athens Medical School, Athens, Greece
Vascul Pharmacol 49:119-33. 2008
..and its most severe extreme the acute respiratory distress syndrome (ARDS) refer to increased-permeability pulmonary edema caused by a variety of pulmonary or systemic insults...
- Usefulness of ultrasound lung comets as a nonradiologic sign of extravascular lung water
Institute of Clinical Physiology, CNR Lab, Via Moruzzi 1, 56123 Pisa, Italy
Am J Cardiol 93:1265-70. 2004
- Streptococcal M1 protein-provoked CXC chemokine formation, neutrophil recruitment and lung damage are regulated by Rho-kinase signaling
Department of Clinical Sciences, Section for Surgery, Malmo University Hospital, Lund University, Malmo, Sweden
J Innate Immun 4:399-408. 2012
- Hypoxic preconditioning with cobalt ameliorates hypobaric hypoxia induced pulmonary edema in rat
Defence Institute of Physiology and Allied Sciences DIPAS, Lucknow Road, Timarpur, Delhi 110054, India
Eur J Pharmacol 656:101-9. 2011
..considered as an acute physiological stress and often leads to high altitude maladies such as high altitude pulmonary edema (HAPE) and high altitude cerebral edema (HACE)...
- Protein kinase C modulates pulmonary endothelial permeability: a paradigm for acute lung injury
Research Service, Stratton Veterans Affairs Medical Center and the Center for Cardiovascular Science, The Albany Medical College, Albany, New York 12208, USA
Am J Physiol Lung Cell Mol Physiol 284:L435-51. 2003
The intracellular serine/threonine kinase protein kinase C (PKC) has an important role in the genesis of pulmonary edema. This review discusses the PKC-mediated mechanisms that participate in the pulmonary endothelial response to agents ..
- Postobstructive pulmonary edema: a case for hydrostatic mechanisms
Richard D Fremont
Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, T1218 MCN, 1161 Twenty First Ave S, Nashville, TN 37232 2650, USA
Chest 131:1742-6. 2007
Postobstructive pulmonary edema is a well-recognized complication of upper airway obstruction...
- Neurogenic pulmonary edema in a fatal case of subarachnoid hemorrhage
Department of Anesthesiology, Hannover Medical School, D 30625 Hannover, Germany
J Clin Anesth 20:129-32. 2008
Neurogenic pulmonary edema (NPE) is caused by a variety of central nervous system lesions and may appear as a subclinical complication. The fulminant form of NPE is always life-threatening...
- Cardiac output increases prior to development of pulmonary edema after re-expansion of spontaneous pneumothorax
H C Tan
Division of Cardiology, Changi General Hospital, Singapore
Respir Med 96:461-5. 2002
b>Pulmonary edema following reexpansion of spontaneous pneumothorax is an uncommon complication. The underlying mechanism of this condition is unclear...
- Negative pressure pulmonary edema after oral and maxillofacial surgery
Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan
Anesth Prog 56:49-52. 2009
Negative pressure pulmonary edema (NPPE) following upper airway obstruction (UAO) has been reported in several clinical situations. The main cause of NPPE is reported to be increased negative intrathoracic pressure...
- Assessment of acute pulmonary edema in dogs by electrical impedance imaging
J C Newell
Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Ttoy, NY 12180, USA
IEEE Trans Biomed Eng 43:133-8. 1996
Acute pulmonary edema was assessed quantitatively in 12 experiments on six anesthetized dogs. Thirty-two copper foil electrodes were placed around each animal's thorax at the level of the third intercostal space...
- Negative pressure pulmonary edema--five case reports
Department of Anaesthesia and Intensive Care, Jordan University Hospital, Amman, Jordan
Middle East J Anesthesiol 18:977-84. 2006
- Update on high-altitude pulmonary edema: pathogenesis, prevention, and treatment
Joshua O Stream
Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, UT, USA
Wilderness Environ Med 19:293-303. 2008
High-altitude pulmonary edema (HAPE) is a life-threatening noncardiogenic form of pulmonary edema (PE) that afflicts susceptible persons after rapid ascent to high altitude above 2500 m...
- Chest sonography: a useful tool to differentiate acute cardiogenic pulmonary edema from acute respiratory distress syndrome
Emergency Department S, Antonio Abate General Hospital, Tolmezzo, Italy
Cardiovasc Ultrasound 6:16. 2008
Differential diagnosis between acute cardiogenic pulmonary edema (APE) and acute lung injury/acute respiratory distress syndrome (ALI/ARDS) may often be difficult...
- Exercise-induced pulmonary edema in heart failure
Centro Cardiologico Monzino, IRCCS, Istituto di Cardiologia, Universita di Milano, Via Parea 4, 20138 Milan, Italy
Circulation 108:2666-71. 2003
..failure (HF) patients, exercise may increase pulmonary capillary hydrostatic pressure and thereby generate pulmonary edema. If pulmonary edema developed, alveolar-capillary membrane conductance (Dm), measured immediately after ..
- Chest ultrasonography for the diagnosis and monitoring of high-altitude pulmonary edema
Peter J Fagenholz
MFA, Department of Emergency Medicine, Clinics 115, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02140, USA
Chest 131:1013-8. 2007
The comet-tail technique of chest ultrasonography has been described for the diagnosis of cardiogenic pulmonary edema. This is the first report describing its use for the diagnosis and monitoring of high-altitude pulmonary edema (HAPE), ..
- Boussignac continuous positive airway pressure for the management of acute cardiogenic pulmonary edema: prospective study with a retrospective control group
Thoraxcenter, Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1 P O Box 30, 001, 9700 RB Groningen, The Netherlands
BMC Cardiovasc Disord 7:40. 2007
Continuous positive airway pressure (CPAP) treatment for acute cardiogenic pulmonary edema can have important benefits in acute cardiac care...
- Negative pressure pulmonary hemorrhage
D R Schwartz
Pulmonary and Critical Care Unit, Massachusetts General Hospital, Boston 02114 2696, USA
Chest 115:1194-7. 1999
Negative pressure pulmonary edema, a well-recognized phenomenon, is the formation of pulmonary edema following an acute upper airway obstruction (UAO)...
- Neurogenic pulmonary edema during intracranial endovascular therapy
Randall P Brewer
Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA
Neurocrit Care 1:423-7. 2004
Neurogenic pulmonary edema (NPE) is a well-known complication of acute brain injury. Neurogenic stunned myocardium (NSM) occurs clinically in a significant subset of patients with NPE...
- Non-invasive pressure support ventilation versus conventional oxygen therapy in acute cardiogenic pulmonary oedema: a randomised trial
Cardiology Department, Consorci Sanitari Creu Roja de Catalunya, Hospital Creu Roja de Barcelona, University of Barcelona, Spain
Lancet 356:2126-32. 2000
..We assessed the efficacy of this therapy in acute cardiogenic pulmonary oedema in a randomised comparison with conventional oxygen therapy...
- Platelet count and function at high altitude and in high-altitude pulmonary edema
Dept of Internal Medicine, Kantonsspital, CH 7000 Chur, Switzerland
J Appl Physiol 100:690-4. 2006
..exposure on platelet function as part of a larger study on 30 subjects with a history of high-altitude pulmonary edema (HAPE) and 10 healthy controls...
- Pathogenesis of high altitude pulmonary edema: does alveolar epithelial lining fluid vascular endothelial growth factor exacerbate capillary leak?
Robert J Kaner
Division of Pulmonary and Critical Care Medicine, Department of Genetic Medicine, Weill Medical College of Cornell University, 515 East 71st Street S 1000, New York, NY 10021, USA
High Alt Med Biol 5:399-409. 2004
..to result in compromise of alveolar epithelial tight junctions and experimental animal studies in which pulmonary edema is induced when VEGF is overexpressed in the alveolar epithelium, suggest a mechanism...
- A comparison of continuous and bi-level positive airway pressure non-invasive ventilation in patients with acute cardiogenic pulmonary oedema: a meta-analysis
Kwok M Ho
Department of Intensive Care, Royal Perth Hospital, Perth, Western Australia, Australia
Crit Care 10:R49. 2006
- Association of polymorphisms in pulmonary surfactant protein A1 and A2 genes with high-altitude pulmonary edema
Institute of Genomics and Integrative Biology, Delhi, India
Chest 128:1611-9. 2005
A potential pathogenetic cofactor for the development of high-altitude pulmonary edema (HAPE) is an increase in capillary permeability, which could occur as a result of an inflammatory reaction and/or free-radical-mediated injury to the ..
- Acute pulmonary edema, capillaritis and alveolar hemorrhage: pulmonary manifestations coexistent in antiphospholipid syndrome and systemic lupus erythematosus?
V A Nguyen
Department of Dermatology, Innsbruck Medical University, Innsbruck, Austria
Lupus 14:557-60. 2005
..described the radiological features of three patients with pulmonary and SLE-associated APS, manifested with pulmonary edema, capillaritis and alveolar hemorrhage...
- Severe subarachnoid hemorrhage with pulmonary edema successfully treated by intra-aneurysmal embolization using Guglielmi detachable coils--Two case reports
Department of Neurosurgery, Aomori Prefectural Central Hospital, Aomori
Neurol Med Chir (Tokyo) 41:135-9. 2001
..Both patients were comatose on admission. Chest radiography disclosed pulmonary edema. They were conservatively treated under controlled ventilation, but cardiopulmonary dysfunction persisted ..
- The detrimental role of inducible nitric oxide synthase in the pulmonary edema caused by hypercalcemia in conscious rats and isolated lungs
Hsing I Chen
Institute of Medical Sciences and of Integrative Physiology and Clinical Sciences, Tzu Chi University, Hualien, Taiwan
J Biomed Sci 15:227-38. 2008
We aim to test the hypothesis that hypercalcemia produces pulmonary edema (PE) and to elucidate the mechanism. Experimentations were carried out in conscious rats and isolated perfused rat lungs...
- Low degree of anesthesia increases the risk of neurogenic pulmonary edema development
Institute of Experimental Medicine, ASCR, Prague, Czech Republic
Med Hypotheses 70:308-13. 2008
Neurogenic pulmonary edema is an acute life-threatening complication following central nervous system injury. The exact pathogenic mechanism leading to its development is still unclear...
- Na,K-ATPase overexpression improves alveolar fluid clearance in a rat model of elevated left atrial pressure
Zaher S Azzam
Technion, Israel Institute of Technology, Haifa, Israel
Circulation 105:497-501. 2002
..We reasoned that adenovirus-mediated transfer of an Na,K-ATPase beta-subunit gene to the alveolar epithelium could improve AFC in rat lungs in the presence of acutely elevated LAP...
- Thoracic impedance vs chest radiograph to diagnose acute pulmonary edema in the ED
Department of Emergency Medicine, Georgetown University Medical Center and Washington Hospital Center, Washington, DC 20010, USA
Am J Emerg Med 27:770-5. 2009
We sought to investigate the relationship between thoracic impedance (Zo) and pulmonary edema on chest radiography in patients presenting to the emergency department (ED) with signs and symptoms of acute decompensated heart failure (ADHF).
- Usefulness of lung ultrasound in the bedside distinction between pulmonary edema and exacerbation of COPD
Department of Emergency Medicine, University of Torino, San Luigi Gonzaga Hospital, Orbassano, Torino, Italy
Emerg Radiol 15:145-51. 2008
..causes of acute dyspnea in the emergency setting, particularly focusing on differential diagnosis of pulmonary edema and exacerbation of chronic obstructive pulmonary disease (COPD)...
- Evaluation of a thoracic ultrasound training module for the detection of pneumothorax and pulmonary edema by prehospital physician care providers
Vicki E Noble
Department of Emergency Medicine, Massachusetts General Hospital, 55 Fruit St, Boston, Massachusetts, USA
BMC Med Educ 9:3. 2009
..skills for two important TUS applications; the identification of B-lines (used in the US diagnosis of pulmonary edema) and the identification of lung sliding and comet tails (used in the US diagnosis of pneumothorax)...
- [The gynecological TURP syndrome. Severe hyponatremia and pulmonary edema during hysteroscopy]
Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitätsklinikum Schleswig Holstein UKSH, Campus Kiel, Schwanenweg 21, 24105 Kiel, Deutschland
Anaesthesist 58:30-4. 2009
..under general anaesthesia, suffering from severe absorption syndrome leading to hyponatremia of 106 mEq/l and pulmonary edema necessitating subsequent admission to ICU...
- Neurogenic pulmonary edema
Departement d Anesthesie Reanimation, Centre Hospitalier Universitaire de Nancy, Hopital Central, Nancy, France
Acta Anaesthesiol Scand 51:447-55. 2007
Neurogenic pulmonary edema (NPE) is usually defined as an acute pulmonary edema occurring shortly after a central neurologic insult...
- Effects of altitude and exercise on pulmonary capillary integrity: evidence for subclinical high-altitude pulmonary edema
Marlowe W Eldridge
John Rankin Laboratory of Pulmonary Medicine, Department of Pediatrics, Univ of Wisconsin, Medical School, H4 422 Clinical Sciences Center, 600 Highland Ave, Madison, WI 53792 4108, USA
J Appl Physiol (1985) 100:972-80. 2006
Strenuous exercise may be a significant contributing factor for development of high-altitude pulmonary edema, particularly at low or moderate altitudes...
- Frequent subclinical high-altitude pulmonary edema detected by chest sonography as ultrasound lung comets in recreational climbers
Institute of Clinical Physiology, CNR, Pisa, Italy
Crit Care Med 38:1818-23. 2010
..The aim of this study was to evaluate, by chest sonography, the incidence of interstitial pulmonary edema in recreational high-altitude climbers.
- Noninvasive ventilation in acute cardiogenic pulmonary edema: systematic review and meta-analysis
ICU Department, Hospital Dos de Maig Consorci Sanitari Integral, University of Barcelona, Barcelona, Spain
JAMA 294:3124-30. 2005
In patients with acute cardiogenic pulmonary edema noninvasive ventilation may reduce intubation rate, but the impact on mortality and the superiority of one technique over another have not been clearly established.
- Bedside lung ultrasound in the assessment of alveolar-interstitial syndrome
Department of Emergency Medicine, S Luigi Hospital, Orbassano, TO, 10043, Italy
Am J Emerg Med 24:689-96. 2006
- Lung edema clearance: 20 years of progress: invited review: role of aquaporin water channels in fluid transport in lung and airways
Will Rogers Institute Pulmonary Research Center, Department of Medicine, University of Southern California, Los Angeles 90033 3721, USA
J Appl Physiol 93:2199-206. 2002
..However, the possibility remains that AQPs may play a role in lung physiology under conditions of stress and/or injury not yet tested or in functions unrelated to transepithelial fluid transport...
- Alveolar epithelial beta2-adrenergic receptors
Gokhan M Mutlu
Northwestern University Feinberg School of Medicine, Pulmonary and Critical Care Medicine, 240 E Huron Street, McGaw M 300, Chicago, IL 60611, USA
Am J Respir Cell Mol Biol 38:127-34. 2008
..agonists to accelerate alveolar fluid clearance in patients with cardiogenic and noncardiogenic pulmonary edema. In this review, we summarize the role of beta(2)-adrenergic receptors in the alveolar epithelium with ..
- Mechanisms of pulmonary edema clearance
Gokhan M Mutlu
Pulmonary and Critical Care Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
Am J Physiol Lung Cell Mol Physiol 289:L685-95. 2005
The mechanisms of pulmonary edema resolution are different from those regulating edema formation...
- "Ultrasound comet-tail images": a marker of pulmonary edema: a comparative study with wedge pressure and extravascular lung water
Division of Non Invasive Cardiology, Cardiothoracic Department, San Raffaele Hospital, Istituto di Richerche e Cura a carattere Scientifico, Milano, Italy
Chest 127:1690-5. 2005
Echographic examination of the lung surface may reveal multiple "comet-tail images" originating from water-thickened interlobular septa. These images could be useful for noninvasive assessment of interstitial pulmonary edema.
- Noninvasive ventilation in acute cardiogenic pulmonary edema
Royal Infirmary of Edinburgh, Edinburgh, United Kingdom
N Engl J Med 359:142-51. 2008
..ventilation [NIPPV]) appears to be of benefit in the immediate treatment of patients with acute cardiogenic pulmonary edema and may reduce mortality...
- Physiological aspects of high-altitude pulmonary edema
Department of Internal Medicine VII, Division of Sports Medicine, Medical University Hospital Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
J Appl Physiol (1985) 98:1101-10. 2005
High-altitude pulmonary edema (HAPE) develops in rapidly ascending nonacclimatized healthy individuals at altitudes above 3,000 m...
- Clara cell protein (CC16), a marker of lung epithelial injury, is decreased in plasma and pulmonary edema fluid from patients with acute lung injury
Jonathan A Kropski
Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 2650, USA
Chest 135:1440-7. 2009
..We tested the diagnostic and prognostic utility of CC16 in patients with non-trauma-related ALI/ARDS compared to a control group of patients with acute cardiogenic pulmonary edema (CPE).
- Mechanism of fulminant pulmonary edema caused by enterovirus 71
Shang Jyh Kao
Department of Chest Medicine, Shin Kong Wu Ho Su Memorial Hospital, School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, Taiwan, Republic of China
Clin Infect Dis 38:1784-8. 2004
b>Pulmonary edema (PE) may occur with enterovirus 71 (EV71) infection. We monitored arterial pressure (AP) and heart rate (HR) in patients with EV71 infection and analyzed the variability of AP and HR...
- The lung is the major site that produces nitric oxide to induce acute pulmonary oedema in endotoxin shock
R P Lee
Institute of Nursing and Medical Sciences and Department of Physiology, Tzu Chi University, Hualien, Taiwan, Republic of China
Clin Exp Pharmacol Physiol 28:315-20. 2001
..Inhalation of NO for patients with sepsis may be used with clinical caution. Therapeutic consideration of lung extracorporeal perfusion with PSS and pharmacological pretreatment with iNOS inhibitors may be warranted...
- Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury
Carolyn S Calfee
Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA, 94143 0111, USA
Intensive Care Med 35:248-57. 2009
..adhesion molecule-1 (sICAM-1), a marker of alveolar epithelial and endothelial injury, differ in patients with hydrostatic pulmonary edema and acute lung injury (ALI) and are associated with clinical outcomes in patients with ALI.
- An increase of abdominal pressure increases pulmonary edema in oleic acid-induced lung injury
Institut fur Anasthesiologie und Operative Intensivmedizin, Universitatsklinikum, Mannheim, Mannheim, Germany
Am J Respir Crit Care Med 169:534-41. 2004
..We conclude that in OA-injured lung, the increase of IAP increases the amount of edema...
- Pulmonary edema after transfusion: how to differentiate transfusion-associated circulatory overload from transfusion-related acute lung injury
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Crit Care Med 34:S109-13. 2006
b>Pulmonary edema is an under-recognized and potentially serious complication of blood transfusion. Distinct mechanisms include adverse immune reactions and circulatory overload...
- Pulmonary blood flow heterogeneity during hypoxia and high-altitude pulmonary edema
Susan R Hopkins
Department of Medicine, Division of Physiology 0623A, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Am J Respir Crit Care Med 171:83-7. 2005
..proposed to expose parts of the pulmonary capillary bed to high pressure and vascular injury in high-altitude pulmonary edema (HAPE)...
- Pulmonary histopathological alterations in patients with acute respiratory failure: an autopsy study
Alexandre de Matos Soeiro
Faculdade de Medicina da Universidade de Sao Paulo FMUSP, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
J Bras Pneumol 34:67-73. 2008
- New classification and clinical characteristics of reexpansion pulmonary edema after treatment of spontaneous pneumothorax
Yun Kwon Kim
Department of Emergency Medicine, Wonju College of Medicine, Yonsei University, Wonju, Republic of Korea
Am J Emerg Med 27:961-7. 2009
Reexpansion pulmonary edema (REPE) is a rare yet sometimes fatal complication associated with the treatment of lung diseases such as pleural effusion, pneumothorax, and hemothorax...
- Alveolar fluid clearance is impaired in the majority of patients with acute lung injury and the acute respiratory distress syndrome
L B Ware
Cardiovascular Research Institute, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0130, USA
Am J Respir Crit Care Med 163:1376-83. 2001
..studies have shown that intact alveolar epithelial fluid transport function is critical for resolution of pulmonary edema and acute lung injury, we measured net alveolar fluid clearance in 79 patients with acute lung injury or the ..
- Stress Doppler echocardiography for identification of susceptibility to high altitude pulmonary edema
Department of Cardiology, University of Heidelberg, Germany
J Am Coll Cardiol 35:980-7. 2000
..This prospective single-blinded study was performed to quantitate noninvasive pulmonary artery systolic pressure (PASP) responses to prolonged acute hypoxia and normoxic exercise...
- Role of lung-marginated monocytes in an in vivo mouse model of ventilator-induced lung injury
Michael R Wilson
Department of Anaesthetics, Pain Medicine and Intensive Care, Faculty of Medicine, Imperial College London, Chelsea, United Kingdom
Am J Respir Crit Care Med 179:914-22. 2009
..Inflammatory subset Gr-1(high) monocytes are recruited to sites of inflammation and have been implicated in acute lung injury induced by systemic endotoxin...
- The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial
Gavin D Perkins
Department of Intensive Care Medicine, Birmingham Heartlands Hospital, UK
Am J Respir Crit Care Med 173:281-7. 2006
..Experimental data suggest that manipulation of alveolar fluid clearance with beta-agonists can accelerate the resolution of alveolar edema and improve survival...
- Accurate characterization of extravascular lung water in acute respiratory distress syndrome
David M Berkowitz
Division of Pulmonary, Allergy and Critical Care, Department of Medicine, Emory University, Atlanta, GA, USA
Crit Care Med 36:1803-9. 2008
Measurements of extravascular lung water (EVLW) correlate to the degree of pulmonary edema and have substantial prognostic information in critically ill patients...
- Intravascular volume monitoring and extravascular lung water in septic patients with pulmonary edema
Polyvalent Intensive Care Unit, University Hospital of Besancon, Boulevard Fleming, 25030 Besancon Cedex, France
Intensive Care Med 28:712-8. 2002
..To evaluate whether different indicators using for guiding volume expansion are valuable tools to assess edematous lung injury in patients with septic shock...
- Acute respiratory distress syndrome of the contralateral lung after reexpansion pulmonary edema of a collapsed lung
Department of Anesthesiology, New York Medical College, Valhalla, NY, USA
J Clin Anesth 16:244-50. 2004
To report that leukocyte-mediated acute injury may develop in a nonhypoxic lung after hypoxia-reoxygenation injury of the hypoxic lung and in other systemic organs in patients with reexpansion pulmonary edema.
- Leptin resistance protects mice from hyperoxia-induced acute lung injury
Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
Am J Respir Crit Care Med 175:587-94. 2007
..Human data suggest that the incidence of acute lung injury is reduced in patients with type II diabetes mellitus. However, the mechanisms by which diabetes confers protection from lung injury are unknown...
- Pulmonary edema following instillation of topical phenylephrine eyedrops in a child under general anesthesia
Department of Anesthesiology, Sankara Nethralaya, Tamil Nadu, India
Eur J Ophthalmol 21:115-7. 2011
To report a case of pulmonary edema, in a child under general anesthesia, due to iatrogenic acute hypertensive crisis following instillation of 1 drop of 5% phenylephrine eyedrops.
- Exacerbation of acute pulmonary edema during assisted mechanical ventilation using a low-tidal volume, lung-protective ventilator strategy
R H Kallet
Department of Anesthesia, University of California, San Francisco, at San Francisco General Hospital, 94110, USA
Chest 116:1826-32. 1999
To assess the magnitude of negative intrathoracic pressure development in a patient whose pulmonary edema acutely worsened immediately following the institution of a low-tidal volume (VT) strategy.
- Acute neurogenic pulmonary edema: case reports and literature review
Ricardo B V Fontes
Neurosurgery and Neurology Clinic Pinheiros, Sao Paulo, Brazil
J Neurosurg Anesthesiol 15:144-50. 2003
Neurogenic pulmonary edema (NPE) is an underdiagnosed clinical entity. Its pathophysiology is multifactorial but largely unknown. We report two cases of NPE and review the literature on NPE cases reported since 1990...
- Usefulness of lung impedance-guided pre-emptive therapy to prevent pulmonary edema during ST-elevation myocardial infarction and to improve long-term outcomes
Heart Institute, Hillel Yaffe Medical Center, Hadera, Rappaport School of Medicine, Technion, Haifa, Israel
Am J Cardiol 110:190-6. 2012
..sustaining an ST-segment elevation myocardial infarction (STEMI) frequently develop pulmonary congestion or pulmonary edema (PED)...
- Adenosine protected against pulmonary edema through transporter- and receptor A2-mediated endothelial barrier enhancement
Vascular Research Laboratory, Providence Veterans Affairs Medical Center, Department of Medicine, Alpert Medical School of Brown University, Providence, Rhode Island 02908, USA
Am J Physiol Lung Cell Mol Physiol 298:L755-67. 2010
..The data suggest that adenosine deaminase inhibition may be useful in treatment of pulmonary edema in settings of ALI.
- Transthoracic monitoring of the impedance of the right lung in patients with cardiogenic pulmonary edema
Department of Internal Medicine C, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Crit Care Med 29:1137-44. 2001
..To evaluate the suitability of the new electrical impedance monitor RS-205 for monitoring of cardiogenic pulmonary edema (CPE). DESIGN: Prospective, controlled study...
- Pulmonary edema in meningococcal septicemia associated with reduced epithelial chloride transport
Institute of Child Health, University of Liverpool, UK
Pediatr Crit Care Med 7:119-24. 2006
To test the hypothesis that meningococcal septicemia-related pulmonary edema is associated with a systemic abnormality of epithelial sodium and chloride transport and to investigate an association with hormones regulating Na transport.
- [Unilateral neurogenic pulmonary edema. A case report]
Service de Pneumologie, Hopital Pasteur, CHU, 30, avenue de la Voie Romaine, BP 69, 06002 Nice cedex 1
Rev Pneumol Clin 60:43-5. 2004
..The patient suddenly developed unilateral pulmonary edema. Bilateral alveolar opacities is the usual radiological aspect of neurogenic pulmonary edema but a unilateral ..
- Patent foramen ovale and high-altitude pulmonary edema
Department of Cardiology, Swiss Cardiovascular Center Bern, University Hospital, Inselspital, Bern, Switzerland
JAMA 296:2954-8. 2006
Individuals susceptible to high-altitude pulmonary edema (HAPE) are characterized by exaggerated pulmonary hypertension and arterial hypoxemia at high altitude, but the underlying mechanism is incompletely understood...
- Ginkgo biloba extract prevents high altitude pulmonary edema in rats
John T Berg
Department of Tropical Medicine, Medical Microbiology, and Pharmacology, University of Hawaii at Manoa, 1951 East West Road, Honolulu, HI 96822, USA
High Alt Med Biol 5:429-34. 2004
Ginkgo biloba reduces the severity of acute mountain sickness in humans, but protection against high altitude pulmonary edema (HAPE) has not been reported. This study was conducted to determine if G...
- [Asymmetric pulmonary perfusion causing unilateral pulmonary edema as a complication of acute myocardial infarction]
Servicio de Cardiologia, Hospital Clinico Universitario, Santiago de Compostela, La Coruna, Spain
Rev Esp Cardiol 58:875-7. 2005
Acute unilateral pulmonary edema is an unusual clinical condition occasionally associated with severe mitral valve insufficiency...
- The role of activation of neutrophils and microvascular pressure in acute pulmonary edema
C E Patterson
Department of Physiology Biophysics, Indiana University School of Medicine, Indianapolis 46223
Am Rev Respir Dis 140:1052-62. 1989
- A difficult diagnosis: right unilateral cardiogenic pulmonary edema. Usefulness of biochemical markers of heart failure for the correct diagnosis
Division of Cardiology, Unit of Polycardiography, University of Brescia, Brescia, Italy
Ital Heart J 6:771-4. 2005
We describe a case of unilateral pulmonary edema occurring in a young woman affected by hypertrophic cardiomyopathy complicated by acute worsening of mitral regurgitation...
- Exposure to hypoxia results in uneven pulmonary blood flow distribution prior to pulmonary edema
Department of Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa 259 1193, Japan
Tokai J Exp Clin Med 30:193-202. 2005
The effects of hypoxia on pulmonary arterial pressure (PAP) and on development of pulmonary edema, ascertained by changes in lung water and pulmonary vascular permeability were studied in rats using bronchoalveolar lavage (BAL)...
- Pulmonary edema: pathophysiology and diagnosis
J F Murray
University of California San Francisco, San Francisco, California, USA
Int J Tuberc Lung Dis 15:155-60, i. 2011
..Lymphatic drainage can increase several-fold, which means that pulmonary edema-defined as an increase in extravascular water content of the lungs-cannot occur until the rate of fluid ..
- Long-term survival and quality of life after transfusion-associated pulmonary edema in critically ill medical patients
Division of Pulmonary and Critical Care Medicine, Old Marion Hall, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, USA
Chest 137:783-9. 2010
..Prior outcome studies of TACO and TRALI have focused on short-term morbidity and mortality, but the long-term survival and quality of life (QOL) of these patients remain unknown...
- Acute pulmonary edema caused by hypoglycemia due to insulin overdose
Department of Endocrinology and Metabolism, Kimitsu Central Hospital, Chiba
Intern Med 43:1056-9. 2004
We report a very rare case of acute pulmonary edema caused by hypoglycemia from insulin overdose during an attempted suicide. A 16-year-old woman with type 1 diabetes was brought to our hospital because of hypoglycemic coma...
- Therapeutic efficacy of milrinone in the management of enterovirus 71-induced pulmonary edema
Shih Min Wang
Department of Emergency Medicine, College of Medicine, National Cheng Kung University and Hospital, Tainan, Taiwan
Pediatr Pulmonol 39:219-23. 2005
..Brain-stem encephalitis and pulmonary edema are severe complications that can lead to death...
- Comparison of a single indicator and gravimetric technique for estimation of extravascular lung water in endotoxemic pigs
Department of Physiology and Pharmacology, Section of Anaesthesiology and Intensive Care Medicine, Karolinska Institute, Stockholm, Sweden
Crit Care Med 34:1437-43. 2006
..To compare the single thermal indicator dilution (STID) technique for measurement of extravascular lung water (EVLW(STID)) with gravimetrically determined EVLW (EVLW(GRAV)) in anesthetized pigs under sham and endotoxemic conditions...
- Importance of anesthesia for the genesis of neurogenic pulmonary edema in spinal cord injury
Manoel Baldoino Leal Filho
Curso de Pósgraduação em Ciências Médicas, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, PO Box 6111, 13084 971 Campinas, SP, Brazil
Neurosci Lett 373:165-70. 2005
There are reports describing both provocation and inhibition of neurogenic pulmonary edema by anesthetic drugs...
- Prehospital lung ultrasound in the distinction between pulmonary edema and exacerbation of chronic obstructive pulmonary disease
Peter Michael Zechner
Medizinercorps Graz, Austrian Red Cross, Naglergasse, Austria
Am J Emerg Med 28:389.e1-2. 2010
We present 2 cases of dyspneic patients, where prehospital lung ultrasound helped to distinguish between pulmonary edema and acute exacerbation of chronic obstructive pulmonary disease.