haemonchiasis

Summary

Summary: Infection with nematodes of the genus HAEMONCHUS, characterized by digestive abnormalities and anemia similar to that from hookworm infestation.

Top Publications

  1. ncbi Anthelmintic activity of Azadirachta indica A. Juss against sheep gastrointestinal nematodes
    C T C Costa
    Faculdade de Veterinaria, Universidade Estadual do Ceara, Av Parajana 1700, 60740 000 Fortaleza, Ceara, Brazil
    Vet Parasitol 137:306-10. 2006
  2. ncbi Haemonchus contortus: in vitro and in vivo anthelmintic activity of aqueous and hydro-alcoholic extracts of Hedera helix
    T Eguale
    Ethiopian Institute of Agricultural Research, National Animal Health Research Center, P O Box 04, Sebeta, Ethiopia
    Exp Parasitol 116:340-5. 2007
  3. ncbi Core alpha1-->3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep
    I Van Die
    Department of Medical Chemistry, Research Institute Immunology and Inflammatory diseases, Vrije Universiteit, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands
    FEBS Lett 463:189-93. 1999
  4. ncbi Estimating genetic differences in natural resistance in Rhön and Merinoland sheep following experimental Haemonchus contortus infection
    M Gauly
    Department of Animal Breeding and Genetics, Oberer Hardthof 18, Justus Liebig University of Giessen, D 35398 Giessen, Germany
    Vet Parasitol 106:55-67. 2002
  5. pmc The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles
    A F Vatta
    Onderstepoort Veterinary Institute, Onderstepoort 0110, South Africa
    Vet Parasitol 162:306-13. 2009
  6. doi Evaluation of immune response to artificial infections of Haemonchus contortus in Gulf Coast Native compared with Suffolk lambs
    K P Shakya
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 181:239-47. 2011
  7. ncbi Testing for clinical anaemia caused by Haemonchus spp. in goats farmed under resource-poor conditions in South Africa using an eye colour chart developed for sheep
    A F Vatta
    Onderstepoort Veterinary Institute, Private Bag X05, 0110, Onderstepoort, South Africa
    Vet Parasitol 99:1-14. 2001
  8. ncbi Epidemiology of gastrointestinal nematode parasitism in Suffolk and Gulf Coast Native sheep with special emphasis on relative susceptibility to Haemonchus contortus infection
    J E Miller
    Department of Epidemiology and Community Health, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA
    Vet Parasitol 74:55-74. 1998
  9. ncbi Effect of CD4+ T lymphocyte depletion on resistance of Gulf Coast Native lambs to Haemonchus contortus infection
    M T Pena
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, 70803, USA
    Vet Parasitol 138:240-6. 2006
  10. doi Microarray analysis reveals difference in gene expression profiles of hair and wool sheep infected with Haemonchus contortus
    K M MacKinnon
    Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, United States
    Vet Immunol Immunopathol 130:210-20. 2009

Research Grants

Detail Information

Publications165 found, 100 shown here

  1. ncbi Anthelmintic activity of Azadirachta indica A. Juss against sheep gastrointestinal nematodes
    C T C Costa
    Faculdade de Veterinaria, Universidade Estadual do Ceara, Av Parajana 1700, 60740 000 Fortaleza, Ceara, Brazil
    Vet Parasitol 137:306-10. 2006
    ..None of the evaluated parameters of the treatment groups were statistically different when compared to the control group, demonstrating that, with the protocol used, A. indica has no anthelmintic effect...
  2. ncbi Haemonchus contortus: in vitro and in vivo anthelmintic activity of aqueous and hydro-alcoholic extracts of Hedera helix
    T Eguale
    Ethiopian Institute of Agricultural Research, National Animal Health Research Center, P O Box 04, Sebeta, Ethiopia
    Exp Parasitol 116:340-5. 2007
    ..helix has a potential anthelmintic benefit and further in vitro and in vivo evaluation of the different parts and fractions is needed to make use of this plant for therapeutic purposes...
  3. ncbi Core alpha1-->3-fucose is a common modification of N-glycans in parasitic helminths and constitutes an important epitope for IgE from Haemonchus contortus infected sheep
    I Van Die
    Department of Medical Chemistry, Research Institute Immunology and Inflammatory diseases, Vrije Universiteit, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands
    FEBS Lett 463:189-93. 1999
    ..Since N-glycans containing the core alpha1-->3-Fuc have also been implicated in honeybee and plant induced allergies, this conserved glycan might represent an important common IgE epitope...
  4. ncbi Estimating genetic differences in natural resistance in Rhön and Merinoland sheep following experimental Haemonchus contortus infection
    M Gauly
    Department of Animal Breeding and Genetics, Oberer Hardthof 18, Justus Liebig University of Giessen, D 35398 Giessen, Germany
    Vet Parasitol 106:55-67. 2002
    ..01). IgG was significantly (P<0.05) and positively correlated with worm burden in male Merinoland and IgL with worm burden in male Rhön sheep...
  5. pmc The potential to control Haemonchus contortus in indigenous South African goats with copper oxide wire particles
    A F Vatta
    Onderstepoort Veterinary Institute, Onderstepoort 0110, South Africa
    Vet Parasitol 162:306-13. 2009
    ..contortus infections in indigenous South African goats, but their use as part of an integrated approach to control H. contortus in the field must be fully investigated...
  6. doi Evaluation of immune response to artificial infections of Haemonchus contortus in Gulf Coast Native compared with Suffolk lambs
    K P Shakya
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 181:239-47. 2011
    ..Native lambs also showed a trend of increased level of serum IgA and IgE compared to Suffolk lambs...
  7. ncbi Testing for clinical anaemia caused by Haemonchus spp. in goats farmed under resource-poor conditions in South Africa using an eye colour chart developed for sheep
    A F Vatta
    Onderstepoort Veterinary Institute, Private Bag X05, 0110, Onderstepoort, South Africa
    Vet Parasitol 99:1-14. 2001
    ..The validation of the FAMACHA system for goats for use by resource-poor farmers, which this paper describes, may have wide application in the tropics and subtropics of sub-Saharan Africa and elsewhere...
  8. ncbi Epidemiology of gastrointestinal nematode parasitism in Suffolk and Gulf Coast Native sheep with special emphasis on relative susceptibility to Haemonchus contortus infection
    J E Miller
    Department of Epidemiology and Community Health, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA
    Vet Parasitol 74:55-74. 1998
    ..contortus) than Suffolk sheep...
  9. ncbi Effect of CD4+ T lymphocyte depletion on resistance of Gulf Coast Native lambs to Haemonchus contortus infection
    M T Pena
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, 70803, USA
    Vet Parasitol 138:240-6. 2006
    ..contortus infection than undepleted lambs. The results of this study suggest that CD4(+) T lymphocytes are associated with the natural resistance of GCN sheep to H. contortus infection...
  10. doi Microarray analysis reveals difference in gene expression profiles of hair and wool sheep infected with Haemonchus contortus
    K M MacKinnon
    Department of Animal and Poultry Sciences, Virginia Tech, Blacksburg, VA 24061, United States
    Vet Immunol Immunopathol 130:210-20. 2009
    ..Changes in these processes indicate Caribbean hair sheep have a stronger inflammatory response when infected with H. contortus which may facilitate the increased parasite resistance observed in these sheep...
  11. doi Comparative experimental Haemonchus contortus infection of two sheep breeds native to the Canary Islands
    Jorge F González
    Departamento de Patologia Animal, Unidad de Parasitologia, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Trasmontana s n, 35413 Arucas, Las Palmas, Spain
    Vet Parasitol 153:374-8. 2008
    ..Overall, these data suggest that the Canaria Hair Breed sheep has a greater resistance to H. contortus infection than Canaria sheep, and that this resistance may act at the level of the adult parasite...
  12. ncbi Performance of hair sheep composite breeds: resistance of lambs to Haemonchus contortus
    H B Vanimisetti
    Department of Animal and Poultry Sciences, Virginia Polytechnic Institute and State University, Blacksburg 24061, USA
    J Anim Sci 82:595-604. 2004
    ..They and the derivative Katahdin breed seem relatively resistant to parasitism. The Dorper, in contrast, was developed in more arid regions and exhibited little parasite resistance...
  13. doi Comparison of parasitological and productive traits of Criollo lambs native to the central Mexican Plateau and Suffolk lambs experimentally infected with Haemonchus contortus
    F Alba-Hurtado
    Departamento de Ciencias Biologicas, Universidad Nacional Autonoma de Mexico, Mexico
    Vet Parasitol 172:277-82. 2010
    ..6+/-1.6kg, and control CNCMP lambs gained 26.9+/-0.8kg. In conclusion, CNCMP lambs had a smaller worm burden, a better ability to maintain their productive traits, and were less affected by infection with Haemonchus contortus...
  14. ncbi Preliminary observations on the potential of gut membrane proteins of Haemonchus contortus as candidate vaccine antigens in sheep on naturally infected pasture
    W D Smith
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Scotland EH26 OPZ, Midlothian, UK
    Vet Parasitol 98:285-97. 2001
    ..It was clear that a vaccine based on parasite gut membrane proteins could offer substantial benefits in the control of natural haemonchosis...
  15. doi Immunoprotective effect of cysteine proteinase fractions from two Haemonchus contortus strains adapted to sheep and goats
    J M Molina
    Unit of Parasitology, Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Trasmontaña s n 35413 Arucas, Las Palmas, Spain
    Vet Parasitol 188:53-9. 2012
    ..This study suggests the possibility of exploring the mechanisms involved in natural protection against non-adapted strains, in order to develop strategies to control haemonchosis...
  16. doi Eosinophils in Haemonchus contortus-infected resistant and susceptible breeds of sheep: abomasal tissue recruitment and in vitro functional state
    G Terefe
    Addis Ababa University, Faculty of Veterinary Medicine, Debre Zeit, Ethiopia
    Vet Parasitol 165:161-4. 2009
    ..Collectively, abomasal eosinophil number and larval killing abilities of blood eosinophils do not seem to explain the difference in worm burden between the two breeds...
  17. ncbi Incidence of Haemonchus spp. and effect on haematocrit and eye colour in goats farmed under resource-poor conditions in South Africa
    A F Vatta
    Onderstepoort Veterinary Institute, Private Bag X05, Onderstepoort 0110, South Africa
    Vet Parasitol 103:119-31. 2002
    ..The use of this system may be recommended as part of an integrated approach to worm control in goats kept in the resource-poor areas studied...
  18. ncbi Clinical evaluation of anaemia in sheep: early trials
    F S Malan
    Intervet Malelane Research Unit, Malelane, South Africa
    Onderstepoort J Vet Res 68:165-74. 2001
    ....
  19. ncbi Control of Haemonchus contortus in goats with a sustained-release multi-trace element/vitamin ruminal bolus containing copper
    J M Burke
    Dale Bumpers Small Farms Research Center, USDA, ARS, Booneville, AR 72927, USA
    Vet Parasitol 141:132-7. 2006
    ..GIN control did not persist more than 28 days. These studies suggest that TEB may be an effective means of GIN control in mature goats, but additional control measures may be necessary...
  20. doi Influence of protein supplementation during late pregnancy and lactation on the resistance of Santa Ines and Ile de France ewes to Haemonchus contortus
    R A Rocha
    UNESP Universidade Estadual Paulista, Departamento de Parasitologia, Instituto de Biociencias, Caixa Postal 510, Botucatu, SP, CEP 18618 000, Brazil
    Vet Parasitol 181:229-38. 2011
    ..Since, unexpectedly, MP scarcity was not achieved in this experiment, our data support the view that Santa Ines ewes are more resistant to H. contortus than Ile de France ewes...
  21. doi Small ruminant resistance against gastrointestinal nematodes: a case of Haemonchus contortus
    Hafiz A Saddiqi
    Department of Zoology, Government College University Faisalabad, Faisalabad, Pakistan
    Parasitol Res 109:1483-500. 2011
    ..This paper reviews the published reports on natural resistance in small ruminants and discusses the prospects of developing small ruminants, which could be resistant to GINs...
  22. doi Genetic analysis of the potential role of IgA and IgE responses against Haemonchus contortus in parasite resistance of Creole goats
    Claudia de la Chevrotière
    UR 143 INRA URZ, Domaine Duclos, 97170 Petit Bourg, Guadeloupe
    Vet Parasitol 186:337-43. 2012
    ..The immune response involving activity of IgE against L3 of H. contortus may be one important pathway for development of resistance to gastrointestinal nematode infections in Creole goats...
  23. ncbi Influence of dietary protein supply on resistance to experimental infections with Haemonchus contortus in Ile de France and Santa Ines lambs
    P A Bricarello
    Departamento de Parasitologia, Instituto de Biociencias, Universidade Estadual Paulista, Botucatu, SP, Brazil
    Vet Parasitol 134:99-109. 2005
    ..05). The present results show that the increase in protein content in growing lamb diets may benefit resistance and resilience to gastrointestinal parasites but that these benefits may vary among breeds...
  24. ncbi Vaccination-induced protection of lambs against the parasitic nematode Haemonchus contortus correlates with high IgG antibody responses to the LDNF glycan antigen
    Lonneke Vervelde
    Utrecht University, Department of Infectious Diseases and Immunology, Division of Parasitology and Tropical Veterinary Medicine, PO Box 80 165, 3508 TD Utrecht, The Netherlands
    Glycobiology 13:795-804. 2003
    ..This combination generated high and specific antiglycan antibody responses that may contribute to the vaccination-induced protection...
  25. doi Decrease in establishment of Haemonchus contortus caused by inoculation of a Taenia hydatigena larvae vesicular concentrate
    C Cuenca-Verde
    Departamento de Ciencias Biologicas, Facultad de Estudios Superiores CuautitlAn, Universidad Nacional Autonoma de Mexico, Estado de Mexico, México CP 54714, Mexico
    Vet Parasitol 177:332-8. 2011
    ..contortus. However, this protection is not only attributable to the role of eosinophils, since ThLVC can function stimulating other immune response cells, such as T lymphocytes, both contributing to prevent the presence of worms...
  26. doi Association between major histocompatibility complex microsatellites, fecal egg count, blood packed cell volume and blood eosinophilia in Pelibuey sheep infected with Haemonchus contortus
    Juan Antonio Figueroa Castillo
    Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, 04510, Mexico, D F, Mexico
    Vet Parasitol 177:339-44. 2011
    ..contortus...
  27. doi Differential immune response between fundic and pyloric abomasal regions upon experimental ovine infection with Haemonchus contortus
    M A Muñoz-Guzmán
    Departamento de Ciencias Biologicas, Universidad Nacional Autonoma de Mexico, Km 2 5 carr Cuautitlán Teoloyucan, Col San Sebastián Xhala Cuautitlán Izcalli, Estado de Mexico, Mexico, CP 54714, Mexico
    Vet Parasitol 185:175-80. 2012
    ..These differences indicate that the immunological response is not homogenous in all abomasal mucosa and that evaluating the response from a single abomasal region may not be representative of the cellular response across the abomasum...
  28. doi Attempts to immunize sheep against Haemonchus contortus using a cocktail of recombinant proteases derived from the protective antigen, H-gal-GP
    E Cachat
    Moredun Research Institute, Edinburgh, Scotland, UK
    Parasite Immunol 32:414-9. 2010
    ....
  29. doi Evaluation of three Pakistani sheep breeds for their natural resistance to artificial infection of Haemonchus contortus
    H A Saddiqi
    Department of Parasitology, University of Agriculture, Faisalabad, Pakistan
    Vet Parasitol 168:141-5. 2010
    ..Breed x week interaction also remained significant (P<0.05) in most of the parameters for Lohi breed. The results suggested that Lohi breed expressed a significant innate resistance to artificial infection of H. contortus...
  30. ncbi Cells, cytokines and other molecules associated with rejection of gastrointestinal nematode parasites
    Els N T Meeusen
    Centre for Animal Biotechnology, School of Veterinary Science, University of Melbourne, Melbourne, VIC 3010, Australia
    Vet Immunol Immunopathol 108:121-5. 2005
    ..In addition, other molecules, in particular carbohydrate binding galectins, may be involved in strengthening the final effector phase of the rejection response...
  31. doi Vaccination against Haemonchus contortus: performance of native parasite gut membrane glycoproteins in Merino lambs grazing contaminated pasture
    L F LeJambre
    CSIRO Livestock Industries, F D McMaster Laboratory, Private Mail Bag, Armidale, NSW 2350
    Vet Parasitol 153:302-12. 2008
    ..It was concluded that if similar protective effects could be obtained with recombinant versions of the proteins present in either H11 or H-gal-GP, then the prospects for a commercial Haemonchus vaccine were real...
  32. ncbi Moxidectin-resistant Haemonchus contortus in sheep in northern New South Wales
    S C J Love
    NSW Agriculture, PO Box 991, Armidale, New South Wales 2350
    Aust Vet J 81:359-60. 2003
  33. ncbi Gastrointestinal nematode challenge induces some conserved gene expression changes in the gut mucosa of genetically resistant sheep
    Aaron Ingham
    CSIRO Livestock Industries, Queensland Bioscience Precinct, 306 Carmody Road, St Lucia, QLD 4067, Australia
    Int J Parasitol 38:431-42. 2008
    ....
  34. ncbi Anthelmintic resistance in South Africa: surveys indicate an extremely serious situation in sheep and goat farming
    J A van Wyk
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
    Onderstepoort J Vet Res 66:273-84. 1999
    ..Alternative methods of integrated worm control, including biological, must be sought and implemented with urgency, to reduce further selection for resistance and to induce reversion of the resistance that has already developed...
  35. ncbi Eosinophil interactions with Haemonchus contortus larvae in the ovine gastrointestinal tract
    A Balic
    Centre for Animal Biotechnology, School of Veterinary Science, The University of Melbourne, Victoria 3010, Australia
    Parasite Immunol 28:107-15. 2006
    ..In addition, they also suggest that effective killing by tissue eosinophils may depend on other microenvironmental factors such as intra-epithelial mast cells and IL-4...
  36. ncbi Molecular characterization and expression of two putative protective excretory secretory proteins of Haemonchus contortus
    H D Schallig
    Department of Parasitology and Tropical Veterinary Medicine, Institute of Infectious Diseases and Immunology, Utrecht University, The Netherlands
    Mol Biochem Parasitol 88:203-13. 1997
    ..Both purified recombinant proteins were recognized by sera from H. contortus hyperimmunised sheep as judged by immunoblot analysis, suggesting that antigenic determinants were also present on the recombinant proteins...
  37. doi Expression of genes in gastrointestinal and lymphatic tissues during parasite infection in sheep genetically resistant or susceptible to Trichostrongylus colubriformis and Haemonchus contortus
    Nicholas Andronicos
    F D Mc Masters Laboratory, CSIRO Livestock Industries, Armidale, Australia
    Int J Parasitol 40:417-29. 2010
    ....
  38. ncbi The development of vaccines against gastrointestinal nematode parasites, particularly Haemonchus contortus
    S E Newton
    Victorian Institute of Animal Science, 475 Mickleham Road, Attwood, Victoria 3049, Australia
    Parasitol Today 15:116-22. 1999
    ..Here, Sue Newton and Ed Munn review the most recent advances in these two main approaches to this problem...
  39. ncbi Lectin staining of trichostrongylid nematode eggs of sheep: rapid identification of Haemonchus contortus eggs with peanut agglutinin
    D G Palmer
    Animal Health Laboratories, Department of Agriculture WA, South Perth, Australia
    Int J Parasitol 26:447-50. 1996
    ..The findings suggest that peanut agglutinin can be used in routine diagnostic parasitology for the rapid identification of H. contortus eggs...
  40. doi Genetic mapping of quantitative trait loci for resistance to Haemonchus contortus in sheep
    K Marshall
    School of Environmental and Rural Science, University of New England, Armidale, NSW 2351, Australia
    Anim Genet 40:262-72. 2009
    ....
  41. ncbi Relationship of abomasal histology and parasite-specific immunoglobulin A with the resistance to Haemonchus contortus infection in three breeds of sheep
    A F T Amarante
    Departamento de Parasitologia, Instituto de Biociencias, Universidade Estadual Paulista, Caixa Postal 510, IB UNESP, Botucatu SP, CEP 18618 000, Brazil
    Vet Parasitol 128:99-107. 2005
    ..Thus, the effect of breed on the functional activity of these and other inflammatory cells is an important area for further study...
  42. ncbi Vaccination against the nematode Haemonchus contortus with a thiol-binding fraction from the excretory/secretory products (ES)
    N Bakker
    Division of Parasitology and Tropical Veterinary Medicine, Department of Infectious Diseases and Immunology, Utrecht University, PO Box 80165, 3508 TD Utrecht, The Netherlands
    Vaccine 22:618-28. 2004
    ....
  43. pmc Evaluation of copper supplementation to control Haemonchus contortus infections of sheep in Sweden
    P J Waller
    Department of Parasitology SWEPAR, National Veterinary Institute and Swedish University of Agricultural Sciences, Uppsala, Sweden
    Acta Vet Scand 45:149-60. 2004
    ..These results indicate that there is little, if any, benefit from a parasite control standpoint in recommending copper therapy, specifically to control parasites in Swedish sheep flocks...
  44. ncbi Interaction between copper oxide wire particles and Duddingtonia flagrans in lambs
    J M Burke
    Dale Bumpers Small Farms Research Center, USDA, ARS, Booneville, AR 72927, USA
    Vet Parasitol 134:141-6. 2005
    ..flagrans, the expected result would be a much lower larval challenge on pasture when these two tools are used together in a sustainable control strategy...
  45. ncbi Immunoprotection in goats against Haemonchus contortus after immunization with cysteine protease enriched protein fractions
    Antonio Ruiz
    Department of Animal Pathology Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Las Palmas de Gran Canaria, Trasmontana s n, 35416 Arucas, Las Palmas, Spain
    Vet Res 35:565-72. 2004
    ..5 +/- 43.8 and 762.5 +/- 78.3 worms per animal in the immunized and nonimmunized goats, respectively. The percentage of egg (89%) and worm (68%) reduction approached those attained with other immunogens used in sheep...
  46. ncbi Immunological aspects of nematode parasite control in sheep
    J E Miller
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, 70803, USA
    J Anim Sci 84:E124-32. 2006
    ..The potential for using vaccines has been investigated, with variable results, for several decades. The few successes and potential new antigen candidates will also be reviewed...
  47. ncbi Protection studies in sheep using affinity-purified and recombinant cysteine proteinases of adult Haemonchus contortus
    Diane L Redmond
    Moredun Research Institute, International Research Centre, Pentlands Science Park, Penicuik, Midlothian EH260PZ, Scotland, UK
    Vaccine 22:4252-61. 2004
    ..Although no reduction in faecal egg counts was observed, sheep vaccinated with recombinant cysteine proteinases showed a highly significant 38% reduction (P <0.01) in worm burdens...
  48. ncbi A novel approach for combining the use of in vitro and in vivo data to measure and detect emerging moxidectin resistance in gastrointestinal nematodes of goats
    R M Kaplan
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Int J Parasitol 37:795-804. 2007
    ..Moxidectin resistance was diagnosed both in Haemonchus and Trichostrongylus on almost half of the farms tested, despite this drug only being used on these farms for 2-3 years...
  49. ncbi Effectiveness of copper oxide wire particles for Haemonchus contortus control in sheep
    M R Knox
    CSIRO Livestock Industries, Pastoral Research Laboratory, Armidale, New South Wales
    Aust Vet J 80:224-7. 2002
    ..To assess the efficacy of copper oxide wire particles (COWP) for the control of H contortus infections in grazing sheep...
  50. ncbi Vaccination against gastrointestinal nematode parasites of ruminants using gut-expressed antigens
    D P Knox
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, Scotland EH26 0PZ, UK
    Vet Parasitol 100:21-32. 2001
    ..In addition, the discussion addresses the utility of selected antigens to protect against co-infecting nematode species such as Teladorsagia circumcincta and against related nematode infections such as Ostertagia ostertagi in cattle...
  51. ncbi Efficacy of copper oxide needles for the control of nematode parasites in dairy goats
    C Chartier
    AFSSA Niort, Laboratoire de Recherches Caprines, France
    Vet Res Commun 24:389-99. 2000
    ..Copper oxide needles may represent an alternative to conventional anthelmintics in the control of Haemonchus infection in some goat farms...
  52. ncbi Cellular profiles in the abomasal mucosa and lymph node during primary infection with Haemonchus contortus in sheep
    A Balic
    Centre for Animal Biotechnology, School of Veterinary Science, The University of Melbourne, VIC 3052, Parkville, Australia
    Vet Immunol Immunopathol 75:109-20. 2000
    ....
  53. doi Assessing the efficacy of Duddingtonia flagrans chlamydospores per gram of faeces to control Haemonchus contortus larvae
    Nadia Florencia Ojeda-Robertos
    Campus de Ciencias Biológicas y Agropecuarias, Universidad Autónoma de Yucatán Carretera Mérida Xmatkuil km 15 5, Merida, Yucatan, Mexico
    Vet Parasitol 158:329-35. 2008
    ..The surface response test indicated that the number of larvae was reduced by CPG until possible saturation. The highest CPG:EPG ratios did not necessarily improve efficacy of D. flagrans...
  54. ncbi Effect of copper oxide wire particles dosage and feed supplement level on Haemonchus contortus infection in lambs
    J M Burke
    Dale Bumpers Small Farms Research Center, USDA, ARS, Booneville, AR 72927, USA
    Vet Parasitol 123:235-43. 2004
    ..PCV values were more favorable for lambs fed the higher level of supplement, especially when FEC were greater than 8000 epg...
  55. ncbi South African field strains of Haemonchus contortus resistant to the levamisole/morantel group of anthelmintics
    J A van Wyk
    Veterinary Research Institute, Onderstepoort, Republic of South Africa
    Onderstepoort J Vet Res 56:257-62. 1989
    ..8%) and morantel (46.2%), the only 2 drugs tested. This is apparently the first report of resistance to the levamisole/morantel group of anthelmintics in sheep in South Africa...
  56. ncbi Use of copper oxide wire particles to control gastrointestinal nematodes in goats
    J M Burke
    ARS, USDA, Booneville, AR 72927, USA
    J Anim Sci 85:2753-61. 2007
    ..Copper oxide does not appear to be effective in controlling newly acquired L4 stage (preadult) larvae, which also feed on blood, leading to decreased PCV in newly infected goats...
  57. ncbi Protective immunity to the blood-feeding nematode Haemonchus contortus induced by vaccination with parasite low molecular weight antigens
    H D Schallig
    Utrecht University, Department of Parasitology and Tropical Veterinary Medicine, The Netherlands
    Parasitology 114:293-9. 1997
    ..However, a marked lower lymphocyte proliferation response was found in non-protected sheep...
  58. ncbi Rapid selection for ivermectin resistance in Haemonchus contortus
    G C Coles
    Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU, UK
    Vet Parasitol 129:345-7. 2005
    ..After three generations the H. contortus was resistant to 0.2 mg/kg ivermectin. The results stress the ease with which ivermectin resistance can be selected if high selection pressure is applied...
  59. ncbi Mechanisms of immunity to Haemonchus contortus infection in sheep
    A Balic
    Centre for Animal Biotechnology, School of Veterinary Science, The University of Melbourne, Victoria, Australia
    Parasite Immunol 24:39-46. 2002
    ..These two immune mechanisms may be associated with the rapid and delayed rejection of parasite infections in immune sheep...
  60. ncbi Accuracy of the FAMACHA system for on-farm use by sheep and goat producers in the southeastern United States
    J M Burke
    Dale Bumpers Small Farms Research Center, USDA, ARS, Booneville, AR 72927, USA
    Vet Parasitol 147:89-95. 2007
    ..These data indicate that the FAMACHA method used by producers is a valuable tool for identifying anemic sheep and goats in the southern United States and Puerto Rico...
  61. pmc Identification of secreted cysteine proteases from the parasitic nematode Haemonchus contortus detected by biotinylated inhibitors
    Ana P Yatsuda
    Division of Infection Biology, Department of Infectious Diseases and Immunology, Utrecht University, Yalelaan, 1, 3584CL, Utrecht, The Netherlands
    Infect Immun 74:1989-93. 2006
    ..Mass spectrometry provided the identification of AC-4, HMCP1, HMCP2, and GCP7 as well as three novel CBLs encoded by clustered expressed sequence tags...
  62. ncbi Vaccines against blood-feeding nematodes of humans and livestock
    J M Bethony
    Centro de Pesquisas René Rachou CPqRR, A FIOCRUZ em Minas Gerais Rene Rachou Research Center CPqRR, The Oswaldo Cruz Foundation, Minas Gerais, Brazil
    Parasitology 133:S63-79. 2006
    ....
  63. ncbi Validation of the FAMACHA eye color chart for detecting clinical anemia in sheep and goats on farms in the southern United States
    R M Kaplan
    Department of Medical Microbiology and Parasitology, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Vet Parasitol 123:105-20. 2004
    ..However, further studies are required to determine optimal strategies for incorporating FAMACHA-based selective treatment protocols into integrated nematode control programs...
  64. ncbi The epidemiology of abomasal nematodes of sheep in Sweden, with particular reference to over-winter survival strategies
    P J Waller
    Department of Parasitology SWEPAR, National Veterinary Institute and Swedish University of Agricultural Sciences, SE 751 89 Uppsala
    Vet Parasitol 122:207-20. 2004
    ..In contrast, T. circumcincta can survive well over-winter, both on pasture and within the host...
  65. ncbi Immune response to Haemonchus contortus infection in susceptible (INRA 401) and resistant (Barbados Black Belly) breeds of lambs
    G Terefe
    Addis Ababa University, Faculty of Veterinary Medicine, Debre Zeit, Ethiopia
    Parasite Immunol 29:415-24. 2007
    ..contortus infection is a Th2-biased immunity in which the BBB showed its maximal performance during the primary infection, the INRA breed performed better after re-infection compared to its response to first exposure...
  66. ncbi Towards the eradication of Haemonchus contortus from sheep flocks in Sweden
    P J Waller
    Department of Parasitology SWEPAR, National Veterinary Institute and Swedish University of Agricultural Sciences, Uppsala, Sweden
    Vet Parasitol 136:367-72. 2006
    ....
  67. ncbi Phenotypic characterization of Haemonchus contortus: a study of isolates from Sweden and Kenya in experimentally infected sheep
    K Troell
    Department of Parasitology SWEPAR, National Veterinary Institute and Swedish University of Agricultural Sciences, 751 89 Uppsala, Sweden
    Parasitology 132:403-9. 2006
    ..This study showed that H. contortus exhibited similar phenotypic traits regardless of geographical origin. Thus, there was limited evidence for adaptations to temperate climatic conditions...
  68. ncbi Segregation of natural and experimental gastrointestinal nematode infection in F2 progeny of susceptible Suffolk and resistant Gulf Coast Native sheep and its usefulness in assessment of genetic variation
    J E Miller
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 140:83-9. 2006
    ..12, and 0.11, 0.22 and 0.12. Based on segregation of infection, larger heritabilities and maternal environment effects that declined after weaning, the summer natural infection was probably the best model for assessing genetic variation...
  69. ncbi Haemonchus contortus and Trichostrongylus colubriformis in pen-trials with Javanese thin tail sheep and Kacang cross Etawah goats
    - Beriajaya
    Research Institute for Veterinary Science, Jl RE Martadinata No 30, Bogor 16114, Indonesia
    Vet Parasitol 135:315-23. 2006
    ..4%), whereas this pattern was reversed in goats and levels were also lower (4.1 and 8.9%, respectively). There was no apparent relationship between eosinophilia and resistance to infection with H. contortus or T. colubriformis...
  70. ncbi Ovicidal and larvicidal activity of Melia azedarach extracts on Haemonchus contortus
    M V Maciel
    College of Veterinary Medicine, Ceara State University, Av Paranjana 1700, Campus do Itaperi, CEP 60740 000, Fortaleza, Ceara, Brazil
    Vet Parasitol 140:98-104. 2006
    ..36mgmL(-1)) and the leaf ethanol extract showed the best inhibition of larval development (LC50=9.18mgmL(-1)). Phytochemical analysis of the most active extracts revealed the presence of condensed tannins, triterpenes and alkaloids...
  71. ncbi Duration of anthelmintic effect of three formulations of ivermectin (oral, injectable and pour-on) against multiple anthelmintic-resistant haemonchus contortus in sheep
    R Garg
    Department of Veterinary Parasitology, College of Veterinary and Animal Sciences, G B P U A and T, Pantnagar 263145, Uttaranchal, India
    Vet Res Commun 31:749-55. 2007
    ....
  72. ncbi In vitro and in vivo anthelmintic activity of crude extracts of Coriandrum sativum against Haemonchus contortus
    T Eguale
    Ethiopian Institute of Agricultural Research, National Animal Health Research Center, P O Box 04, Sebeta, Ethiopia
    J Ethnopharmacol 110:428-33. 2007
    ..Treatment with both doses of Coriandrum sativum did not help the animals improve or maintain their PCV while those treated with albendazole showed significant increase in PCV (p<0.05)...
  73. ncbi Attempts to detect synergy between vaccination and anthelmintic against a drug resistant isolate of Haemonchus contortus
    W D Smith
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Scotland EH26 0PZ, UK
    Vet Parasitol 148:356-9. 2007
    ..It was concluded that there was no evidence for synergy between a gut membrane protein vaccine and ivermectin or fenbendazole against an anthelmintic resistant isolate of H. contortus...
  74. ncbi Direct and indirect anthelmintic effects of condensed tannins in sheep
    Zafar Iqbal
    Chemotherapy Laboratory, Department of Veterinary Parasitology, University of Agriculture, Faisalabad 38040, Pakistan
    Vet Parasitol 144:125-31. 2007
    ..The direct anthelmintic effect of CT, therefore, was evidenced by inhibited egg hatching; whereas, faecal egg counts reduction in sheep was through improved nutrient utilization...
  75. ncbi [Experiences with the FAMACHA-Eye-Colour-Chart for identifying sheep and goats for targeted anthelmintic treatment]
    Regine Koopmann
    Institut für okologischen Landbau der Bundesforschungsanstalt für Landwirtschaft
    Berl Munch Tierarztl Wochenschr 119:436-42. 2006
    ..But if not working hours are the limiting factor, the repeated score could support the selection of pale animals in need to be treated...
  76. ncbi Effect of sainfoin (Onobrychis viciifolia) silage and hay on established populations of Haemonchus contortus and Cooperia curticei in lambs
    Felix Heckendorn
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, CH 5070 Frick, Switzerland
    Vet Parasitol 142:293-300. 2006
    ..For both, hay and silage, an antiparasitic effect could be shown, offering promising perspectives for the use of conserved tanniferous fodder as a complementary control approach against GIN...
  77. ncbi Influence of sex on the resistance of sheep lambs to an experimental Haemonchus contortus infection
    M Gauly
    Institute of Animal Breeding and Genetics, University of Gottingen, Germany
    Dtsch Tierarztl Wochenschr 113:178-81. 2006
    ..Therefore male breeding values are probably not representative for the whole population...
  78. ncbi Effect of nutritional status and fat reserves on the periparturient immune response to Haemonchus contortus infection in sheep
    J Valderrabano
    Centro de Investigación y Tecnología Agroalimentaria de Aragón, Zaragoza, Spain
    Vet Parasitol 141:122-31. 2006
    ..Furthermore, the differences in the immune response appeared associated with serum leptin levels suggesting that leptin may be a key link between nutritional status and the protective immune reactivity against GI nematode infection...
  79. ncbi Performance and nematode infection of ewe lambs on intensive rotational grazing with two different cultivars of Panicum maximum
    R L D Costa
    Apta RegionalExtremo Oeste, Andradina, SP, Brazil
    Trop Anim Health Prod 39:255-63. 2007
    ..2% crude protein in Aruana grass and 8.7% in Tanzania grass, p < 0.05) which may have improved the immunological system with the consequence that the highest PCV (p < 0.05) observed in those animals...
  80. ncbi Trichostrongylus colubriformis and Haemonchus contortus infections in light bodyweight Merino lambs
    S J McClure
    FD McMaster Laboratory, CSIRO Livestock Industries, Locked Bag 1, Delivery Centre, Armidale NSW 2350, Australia
    Aust Vet J 85:437-45. 2007
    ..OBJECTIVE; To show that low bodyweight is a predisposing cause of high Trichostrongylus colubriformis and Haemonchus contortus burdens and egg counts in Merino lambs...
  81. ncbi Efficacy of the nematode-trapping fungus Duddingtonia flagrans against infections by Haemonchus and Trichostrongylus species in lambs at pasture
    R A Rocha
    UNESP, Sao Paulo State University, Instituto de Biociencias, Departamento de Parasitologia, Caixa Postal 510, CEP 18618 000, Botucatu, SP, Brazil
    J Helminthol 81:387-92. 2007
    ..05). Feeding sheep with pellets containing D. flagrans had no benefit to the prophylaxis of nematode infections under the experimental conditions used in the present study...
  82. ncbi Further protection studies using recombinant forms of Haemonchus contortus cysteine proteinases
    D L Redmond
    Moredun Research Institute, International Research Centre, Pentlands Science Park, Penicuik, Midlothian, UK
    Parasite Immunol 28:213-9. 2006
    ..Sera from these groups bound to the microvillar surface of the gut of H. contortus...
  83. ncbi A survey on anthelmintic resistance in nematode parasites of sheep in Lusaka, Zambia
    S Gabrie
    Department of Clinical Studies, School of Veterinary Medicine, University of Zambia, Lusaka
    Onderstepoort J Vet Res 68:271-4. 2001
    ..On each of the four farms where ivermectin gave less than 95% reduction in egg counts, there was resistance to albendazole as well. Levamisole showed an efficacy of 95% or higher on all six farms...
  84. ncbi Field studies on the biological control of nematode parasites of sheep in the tropics, using the microfungus Duddingtonia flagrans
    P Chandrawathani
    Veterinary Research Institute, 59 Jalan Sultan Azlan Shah, 31400 Ipoh, Malaysia
    Vet Parasitol 120:177-87. 2004
    ..These results show that the deployment of the nematophagous fungus, D. flagrans, can improve the level of parasite control of sheep in the tropics above that which can be achieved by the short-term rotational grazing strategy alone...
  85. ncbi Effect of dexamethasone treatment on the immune response of Gulf Coast Native lambs to Haemonchus contortus infection
    M T Pena
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 119:223-35. 2004
    ..contortus infection. The results of these studies suggest that some aspects of the immune response may underlie the natural resistance of Native sheep to H. contortus infection...
  86. ncbi Efficiency of feeding Duddingtonia flagrans chlamydospores to grazing ewes on reducing availability of parasitic nematode larvae on pasture
    M E Fontenot
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 118:203-13. 2003
    ..This study showed that D. flagrans, fed daily to grazing ewes, was an effective biological control agent in reducing a predominantly H. contortus larval population on pasture...
  87. ncbi The anthelmintic efficacy of five plant products against gastrointestinal trichostrongylids in artificially infected lambs
    P Hördegen
    Department of Veterinary Parasitology, Research Institute of Organic Agriculture, Ackerstrasse, CH 5070 Frick, Switzerland
    Vet Parasitol 117:51-60. 2003
    ..Therefore, the ethanol extract itself or single constituents of F. parviflora could be a promising alternative source of anthelmintic for the treatment of gastrointestinal trichostrongylids in small ruminants...
  88. ncbi The anthelmintic efficacy of the plant, Albizia anthelmintica, against the nematode parasites Haemonchus contortus of sheep and Heligmosomoides polygyrus of mice
    John B Githiori
    International Livestock Research Institute ILRI, P O Box 30709, Nairobi, Kenya
    Vet Parasitol 116:23-34. 2003
    ..anthelmintica preparation resulted in death of all mice. The results show that A. anthelmintica at the doses and preparations used is not efficacious against H. contortus in sheep or against H. polygyrus in mice...
  89. ncbi Epidemiology of parasitic gastrointestinal nematode infections of ruminants on smallholder farms in central Kenya
    J M Nginyi
    National Veterinary Research Centre, Muguga, KARI, Kikuyu, PO Box 32, Kenya
    Res Vet Sci 70:33-9. 2001
    ..Based on this study, it is now possible to explore the possibility of using strategic treatments for the control of parasitic gastroenteritis in this area of Kenya...
  90. ncbi Top dressing of feed with desiccated chlamydospores of Duddingtonia flagrans for biological control of the pre-parasitic stages of ovine Haemonchus contortus
    P K Sanyal
    Biotechnology Laboratory, National Dairy Development Board, Anand 388 001, Gujarat, India
    Vet Res Commun 27:381-90. 2003
    ..Top dressing supplementary feed with dried chlamydospores offers a potential way of using D. flagrans for biological control of the pre-parasitic stages of H. contortus...
  91. ncbi Metalloendopeptidases from the intestinal brush border of Haemonchus contortus as protective antigens for sheep
    W D Smith
    Moredun Research Institute, Penicuik, Midlothian, EH26 OPZ UK
    Parasite Immunol 25:313-23. 2003
    ....
  92. ncbi The effects of ivermectin and moxidectin on egg viability and larval development of ivermectin-resistant Haemonchus contortus
    K L Tyrrell
    CSIRO Livestock Industries, Locked Bag 1, Armidale NSW, Australia
    Vet Parasitol 107:85-93. 2002
    ....
  93. ncbi Efficacy of albendazole and levamisole against gastrointestinal nematodes of sheep and goats in Morogoro, Tanzania
    J D Keyyu
    Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine, Sokoine University of Agriculture, PO Box 3019, Morogoro, Tanzania
    Trop Anim Health Prod 34:115-20. 2002
    ..A reduced efficacy of levamisole was suspected...
  94. ncbi Evolution of high-level, multiple anthelmintic resistance on a sheep farm in Malaysia
    P Chandrawathani
    Veterinary Research Institute, 59 Jalan Sultan Azlan Shah, 31400 Ipoh, Malaysia
    Trop Anim Health Prod 35:17-25. 2003
    ..There is an urgent need to evaluate other control strategies that incorporate livestock management, the 'smart' use of drugs and non-chemotherapeutic approaches, such as biological control agents...
  95. ncbi Evaluation of Duddingtonia flagrans in reducing infective larvae of Haemonchus contortus in feces of sheep
    M T Pena
    Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA 70803, USA
    Vet Parasitol 103:259-65. 2002
    ..flagrans was highly effective in reducing infective larvae in sheep feces and should be considered as a biological control agent for integrated nematode control programs...
  96. ncbi The FAMACHA system for managing haemonchosis in sheep and goats by clinically identifying individual animals for treatment
    Jan A van Wyk
    Department of Veterinary Tropical Diseases, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa
    Vet Res 33:509-29. 2002
    ..contortus for anthelmintic resistance...
  97. ncbi Genetic parameters for resistance to Haemonchus contortus in Merino sheep in South Africa
    S W Nieuwoudt
    ARC Animal Improvement Institute, Irene, South Africa
    J S Afr Vet Assoc 73:4-7. 2002
    ..13 +/- 0.09). These results suggest that FEC can be used as a selection criterion for resistance to H. contortus infections in Merino sheep...
  98. ncbi Comparison of the resistance to sympatric and allopatric isolates of Haemonchus contortus of Black Belly sheep in Guadeloupe (FWI) and of INRA 401 sheep in France
    G Aumont
    INRA, Unité de zootechnie, BP 515, 97165, Pointe a Pitre, France
    Vet Parasitol 116:139-50. 2003
    ..The regulation of worm population and fecundity differed in the BB and INRA 401 sheep...
  99. ncbi Protection induced by vaccinating sheep with a thiol-binding extract of Haemonchus contortus membranes is associated with its protease components
    D P Knox
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, UK
    Parasite Immunol 27:121-6. 2005
    ..Immunization stimulated a marked IgG response with the IgG2 isotype predominating...
  100. ncbi Characterization of moxidectin resistant Trichostrongylus colubriformis and Haemonchus contortus
    L F Le Jambre
    CSIRO Livestock Industries, Locked Bag 1, Armidale, NSW 2350, Australia
    Vet Parasitol 128:83-90. 2005
    ..A dose rate of 8 mg/kg levamisole and 185 mg/kg napthalophos achieved >95% reduction in worm count of the MOX-R homozygous H. contortus but only 85 and 7%, respectively against the MOX-R homozygous T. colubriformis...
  101. ncbi [Use of FAMACHA Scoring System as a diagnostic aid for the registration of distinguishing marks in the breeding program for lambs exposed to an experimental Haemonchus contortus infection]
    M Gauly
    Institut für Tierzucht und Haustiergenetik der Georg August Universität Göttingen
    Dtsch Tierarztl Wochenschr 111:430-3. 2004
    ..The estimated correlations have been low. This proofs the limits of the FAMACHA system under a situation of low parasite pressure...

Research Grants4

  1. TRICHINELLOSIS AND REGULATION OF HOST GENE EXPRESSION
    Douglas Jasmer; Fiscal Year: 2001
    ..Understanding these mechanisms may also contribute unique insight on mechanisms of muscle differentiation and cell cycle regulation in mammalian cells. ..