Genomes and Genes
Summary: The formation of spongy bone in the labyrinth capsule. The ossicles can become fixed and unable to transmit sound vibrations, thereby causing deafness.
Publications200 found, 100 shown here
- Argon laser assisted small fenestra stapedotomy for otosclerosisVivek Raut
New Cross Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UK
Auris Nasus Larynx 32:11-5. 2005To report and analyse our results and complications of argon laser assisted stapedotomy for primary otosclerosis. A retrospective analysis of 135 consecutive cases of primary otosclerosis operated by the senior author (JH) has been ..
- Audiological long-term results following stapedotomy with stapedial tendon preservationA Arnold
HNO Klinik, Inselspital, Universitat Bern, Bern, Switzerland
Adv Otorhinolaryngol 65:210-4. 2007..These favorable results remained constant in long-term controls...
- The etiology of otosclerosis: a combination of genes and environmentIsabelle Schrauwen
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Laryngoscope 120:1195-202. 2010b>Otosclerosis is a common form of hearing loss characterized by abnormal bone remodeling in the otic capsule. It is a complex genetic disease, caused by a combination of genetic and environmental factors...
- New aspects in the clinical diagnosis of otosclerosis using laser Doppler vibrometryAndre Jakob
TU Dresden, Department of Medicine, Clinic of Otorhinolaryngology, Dresden, Germany
Otol Neurotol 30:1049-57. 2009..Laser Doppler vibrometry (LDV) applied to umbo motion measurement in healthy and otosclerotic ears shows statistically tested differences...
- Diode laser in otosclerosis surgery: first clinical resultsYann Nguyen
Hopital Beaujon, Service d ORL et de Chirurgie Cervico faciale, Clichy, France
Otol Neurotol 29:441-6. 2008To evaluate the functional results of otosclerosis surgery using diode laser.
- Histologic changes on stapedial footplate in otosclerosis. Correlations between histologic activity and clinical findingsAnton Gros
Department of Otorhinolaryngology and Cervicofacial Surgery, University Medical Center Ljubljana, Slovenia
Otol Neurotol 24:43-7. 2003To quantify the relationship between the stage of histologic changes of the stapedial footplate in otosclerosis and the magnitude of preoperative hearing loss, tinnitus, vestibular disorder, and postoperative improvement of hearing.
- Stapedectomy versus stapedotomy: comparison of results with long-term follow-upHoward P House
House Ear Clinic, Los Angeles, California 90057, USA
Laryngoscope 112:2046-50. 2002To compare the effectiveness and long-term stability of hearing results between stapedectomy and small fenestra stapedotomy in patients with conductive hearing loss due to otosclerosis.
- Association between cupular deposits and otosclerosisHideo Hayashi
Department of Otolaryngology, Otitis Media Research Center, University of Minnesota, Minneapolis, USA
Arch Otolaryngol Head Neck Surg 132:1331-4. 2006To evaluate whether otosclerosis is an underlying mechanism for the production of cupular deposits and to study the association between cupular deposits and dysequilibrium in otosclerosis.
- Otosclerosis or congenital stapes ankylosis? The diagnostic role of genetic analysisSarah B Emery
Division of Pediatric Otolaryngology, Department of Otolaryngology Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan, USA
Otol Neurotol 30:1204-8. 2009Molecular genetic testing is useful to differentiate otosclerosis from syndromic stapes ankylosis.
- Round window otosclerosis: radiologic classification and clinical correlationsSalah Mansour
Division of Otolaryngology HNS, Faculty of Medical Sciences, Lebanese University, Beirut, Lebanon
Otol Neurotol 32:384-92. 2011To develop a radiologic classification of severity of round window involvement in otosclerosis and describe the impact of each class on hearing and outcome of stapes surgery.
- Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2I Schrauwen
Department of Medical Genetics, University of Antwerp, Belgium
Genes Immun 11:246-53. 2010b>Otosclerosis is a common form of hearing loss, characterized by disordered bone remodeling in the otic capsule. Within the otosclerotic foci, several immunocompetent cells and immune-modulating factors can be found...
- Influence of a totally open oval window on bone conduction in otosclerosisAndreas Arnold
University Department of ENT, Head and Neck Surgery, Inselspital, University of Berne, Berne, Switzerland
Audiol Neurootol 16:23-8. 2011..The aim of this study was to evaluate changes in bone conduction thresholds before, during and after total stapedectomy...
- Far advanced otosclerosis and intractable benign paroxysmal positional vertigo treated with combined cochlear implantation and posterior semicircular canal occlusionG Crossland
Department of Otolaryngology, Addenbrooke s Hospital, Cambridge, UK
J Laryngol Otol 118:302-4. 2004..benign paroxysmal positional vertigo (BPPV) and profound hearing loss in a patient with far advanced otosclerosis. The procedure comprised of a posterior semicircular canal occlusion and cochlear implantation as one combined ..
- Histopathological incidence of facial canal dehiscence in otosclerosisShigenobu Nomiya
Department of Otolaryngology, University of Minnesota, Minneapolis, MN, 55455, USA
Eur Arch Otorhinolaryngol 268:1267-71. 2011The objective of this study was to evaluate the histopathological incidence of facial canal dehiscence in otosclerosis cases compared with non-otosclerotic controls...
- Perioperative recordings of vestibular-evoked myogenic potentials in otosclerosisFabian Singbartl
Department of Otolaryngology at Unfallkrankenhaus Berlin, Hospital of the University of Berlin, Charite Medical School, Berlin, Germany
Otol Neurotol 27:1070-3. 2006The aim of the present study was to investigate saccular function in patients with otosclerosis. Furthermore, the influence of stapedotomy on the vestibular-evoked myogenic potentials (VEMPs) should be demonstrated.
- Failures in stapedotomy for otosclerosisGregorio G Babighian
Department of Otolaryngology Otosurgery, Azienda Ospedaliera Università, Padova, Italy
Otolaryngol Head Neck Surg 141:395-400. 2009..To review the results of 78 revision stapedotomies, determining the causes of failure and the predictors of surgical success...
- New perspectives for middle ear implants: first results in otosclerosis with mixed hearing lossFrederic Venail
ENT Department, Hopital Nord, APHM, Marseille, France
Laryngoscope 117:552-5. 2007..Implantation of such devices requires ossicular chain integrity. Patients suffering from otosclerosis with mixed HL should be eligible for this treatment after stapes surgery with air-bone gap closure...
- Vestibular-evoked myogenic potentials in patients with otosclerosis using air- and bone-conducted tone-burst stimulationTsung Lin Yang
Department of Otolaryngology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan
Otol Neurotol 28:1-6. 2007b>Otosclerosis is a progressive disease with a remodeling process causing ossicular malformation and conductive hearing loss...
- Measles virus and otosclerosisH P Niedermeyer
Department of Otorhinolaryngology, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
Adv Otorhinolaryngol 65:86-92. 2007Measles virus (MeV) might play an important role as an environmental stimulus in the etiopathogenesis of otosclerosis. Chronic inflammation was shown in morphologic investigations of otosclerotic foci and MeV N, P, and F proteins were ..
- OtosclerosisMegan Ealy
Molecular Otolaryngology Research Laboratories, Department of Otolaryngology, Interdisciplinary Graduate Program in Genetics, University of Iowa, Iowa City, Iowa, USA
Adv Otorhinolaryngol 70:122-9. 2011b>Otosclerosis is one of the more common forms of adult-onset hearing loss with a prevalence of 0.3-0.4% in Caucasians...
- Otosclerosis: selection of ear for cochlear implantationAlexia Georgina Matterson
The Department of Otolaryngology, The University of Melbourne, Melbourne, Australia
Otol Neurotol 28:438-46. 2007..2. To examine whether the rate of facial nerve stimulation postoperatively is correlated with the type of electrode used...
- Surgical findings and long-term hearing results in 3,050 stapedotomies for primary otosclerosis: a prospective study with the otology-neurotology databaseRobert Vincent
Jean Causse Ear Clinic, Traverse de Béziers, Colombiers, France
Otol Neurotol 27:S25-47. 2006To evaluate with a new otologic database the results of primary stapes surgery for otosclerosis with up to 14 years of follow-up in a consecutive series of 2,525 patients operated on by the same surgeon with the same technique (..
- Shape-memory stapes prosthesis for otosclerosis surgeryGlenn W Knox
Northeast Florida Ear Research Institute, University of Florida, 3663 Crown Point Court, Jacksonville, FL 32257, U S A
Laryngoscope 115:1340-6. 2005..The aim of this study was to determine the efficacy of a shape-memory alloy, Nitinol, as a component of an improved stapes prosthesis...
- Revision cochlear implantation for facial nerve stimulation in otosclerosisMarek Polak
University of Miami Ear Institute, Miami, FL, USA
Arch Otolaryngol Head Neck Surg 132:398-404. 2006To find if patients experiencing postsurgical facial nerve stimulation caused by underlying disease process (ie, otosclerosis) can improve their hearing performance with their cochlear implant by reimplantation and by an optimal ..
- Cochlear implantation in cochlear otosclerosisA H Marshall
Department of Otolaryngology Head and Neck Surgery, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Laryngoscope 115:1728-33. 2005The objective was to correlate implant performance in cochlear otosclerosis to 1) matched control samples, 2) severity of otic capsule involvement, 3) prior ipsilateral surgery, and 4) programming issues.
- Latent superior canal dehiscence syndrome unmasked by stapedotomy for otosclerosisA Hope
Department of Otolaryngology, St Vincent s Private Hospital, Sydney, 406 Victoria Street, Darlinghurst, New South Wales 2010, Australia
J Laryngol Otol 124:428-30. 2010This report describes a novel case in which superior canal dehiscence syndrome was unmasked by successful stapes surgery for otosclerosis.
- Nystagmus induced by bone (mastoid) vibration in otosclerosis: a new perspective in the study of vestibular function in otosclerosisLeonardo Manzari
Department of Experimental Medicine and Pathology, La Sapienza University, Rome, Italy
Med Sci Monit 14:CR505-10. 2008..vestibular responses to bone vibration-induced nystagmus (BVIN) during bed-side examination in patients with otosclerosis and conductive hearing loss...
- Blood flow to the promontory in cochlear otosclerosisT Nakashima
Department of Otorhinolaryngology, Nagoya University School of Medicine, Showa Ku, Japan
Clin Otolaryngol 31:110-5. 2006To investigate Schwartze sign with measurements of blood flow to the promontory in patients with cochlear otosclerosis.
- Cochlear implantation in 53 patients with otosclerosis: demographics, computed tomographic scanning, surgery, and complicationsLiselotte J C Rotteveel
Department of Otorhinolaryngology, University Medical Center, Nijmegen, The Netherlands
Otol Neurotol 25:943-52. 2004To collect data from a large number of cochlear implant recipients with otosclerosis and to make an assessment of these patients' clinical characteristics, computed tomographic scans, surgical findings, and complications, and to quantify ..
- [Otosclerosis and Van der Hoeven's syndrome: a contribution]L A Vallejo Valdezate
Servicio de ORL, , C/Cardenal Torquemada, s/n. 47010 Valladolid
Acta Otorrinolaringol Esp 52:85-93. 2001..This finding indicates a possible change from hydroxyapatite (or apatite) to brushite, which imply an acidification of bone...
- Tight stapes prosthesis fixation leads to better functional results in otosclerosis surgeryAlexander M Huber
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Zurich, Germany
Otol Neurotol 29:893-9. 2008..Tight fixation of stapes prostheses yields better functional results because sound transmission from the incus to the prosthesis is improved...
- Spiral ligament and stria vascularis changes in cochlear otosclerosis: effect on hearing levelJoni K Doherty
Department of Otolaryngology Head and Neck Surgery, University of Southern California, Los Angeles, USA
Otol Neurotol 25:457-64. 2004To investigate the effect of changes within the spiral ligament and stria vascularis on hearing in cochlear otosclerosis, we examined spiral ligament hyalinization, stria vascularis atrophy, and sensory hearing loss in cochlear ..
- Otosclerosis: an organ-specific inflammatory disease with sensorineural hearing lossIstvan Sziklai
Department of Otorhinolaryngology, Head and Neck Surgery, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary
Eur Arch Otorhinolaryngol 266:1711-8. 2009b>Otosclerosis is an inflammatory disease associated with persistent measles virus (MV) infection of the otic capsule...
- Glucocorticoids inhibit diastrophic dysplasia sulfate transporter activity in otosclerosis by interleukin-6Yutaka Imauchi
Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, University of Tokyo, Japan
Laryngoscope 116:1647-50. 2006b>Otosclerosis is a bone remodeling disorder localized to the otic capsule and associated with inflammation...
- Pathophysiology of otosclerosisR A Chole
Department of Otolaryngology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
Otol Neurotol 22:249-57. 2001OBJECTIVE: To review current knowledge of the pathophysiology of otosclerosis and to review hypotheses for the amelioration of this disease. DATA SOURCES: Review of the literature and experimental observations by the authors...
- A genome-wide analysis identifies genetic variants in the RELN gene associated with otosclerosisIsabelle Schrauwen
Department of Medical Genetics, University of Antwerp, Antwerp, Belgium
Am J Hum Genet 84:328-38. 2009b>Otosclerosis is a common form of progressive hearing loss, characterized by abnormal bone remodeling in the otic capsule. The etiology of the disease is largely unknown, and both environmental and genetic factors have been implicated...
- Experience with a new pure gold piston in stapedotomy for cases of otosclerosisR A Tange
Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, The Netherlands
Auris Nasus Larynx 25:249-53. 1998..9%) piston in cases of otosclerosis. A retrospective analysis of the pre- and postsurgery audiological results of these patients was carried out by ..
- Reparative granuloma seen in cases of gold piston implantation after stapes surgery for otosclerosisRinze A Tange
Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Auris Nasus Larynx 29:7-10. 2002to determine the occurrence of the unusual side effect of a reparative granuloma after the implantation of a pure gold piston in cases of otosclerosis.
- Stapes prosthesis attachment: the effect of crimping on sound transfer in otosclerosis surgeryAlexander M Huber
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Zurich, Switzerland
Laryngoscope 113:853-8. 2003..The objectives of the study were to assess the amount of sound transmission loss in response to the quality of prosthesis crimping and to identify a required loop attachment pattern to obtain good sound transmission results...
- Vibrant soundbridge middle ear implant in otosclerosis: technique - indicationThibaud Dumon
J Causse Clinic, Beziers, France
Adv Otorhinolaryngol 65:320-2. 2007..VSB) middle ear implant, the question emerged of its indication in mixed hearing loss due to advanced otosclerosis. We describe the VSB implantation technique in primary otosclerosis performed together with a stapedotomy ..
- [Cochlear protection and surgical precision in stapedotomy with Er:YAG laser]W Maier
Klinik fur Hals, Nasen und Ohren Heilkunde, Universitätsklinikum Freiburg i Br
Laryngorhinootologie 85:333-7. 2006..We analyzed the clinical effect of Er:YAG laser with the question whether the postulated cochlea protection and foot plate perforation, optimized for better sound conduction, are achieved, compared to conventional stapedotomy...
- The effect of stapes mobility on hearing outcome and which procedure to choose in fixed stapes in children tympanosclerosisZeynep Kizilkaya
Ministry of Health Ankara Research and Training Hospital, E N T Department, Turkey
Int J Pediatr Otorhinolaryngol 72:849-56. 2008..Our objective was to evaluate the features of tympanosclerosis in children and to determine the effect of stapes mobility and the type of one-stage operation on hearing outcomes...
- "Second ear" stapedotomy: is it safe?Ch G Albrechet
Department of Otolaryngology and Head and Neck Surgery, Campinas State University, Campinas, Sao Paulo, Brazil
Acta Otorhinolaryngol Belg 58:109-11. 2004This study reports the evaluation of "second ear" stapedotomiesy results in 23 patients with otosclerosis. All pre- and post-operative audiological data, all relevant surgical information and patients' features were analyzed ..
- Stapedectomy in congenital stapes fixation: are hearing outcomes poorer?Becky L Massey
Division of Otolaryngology Head and Neck Surgery, University of Utah, Salt Lake City, UT 84132, USA
Otolaryngol Head Neck Surg 134:816-8. 2006..To evaluate outcomes of stapedectomy surgery for congenital stapes fixation...
- Revision stapes surgeryKlaus Jahnke
Department of Otorhinolaryngology, University Hospital of Essen, Essen, Germany
Adv Otorhinolaryngol 65:314-9. 2007..In a second series, a significant hearing improvement of 76.2% was found. One patient with a platinum Teflon implant had to be revised because of vertigo and conductive hearing loss which was observed during MRI...
- Stapes surgery in residency: the UFPR clinical hospital experienceAdriano Ulisses Caldart
Braz J Otorhinolaryngol 73:647-53. 2007Surgery of the stapedius remains the established treatment for otosclerosis. Recent publications have showed that success in surgeries done by residents have decreased and hearing results are worse than those obtained by experienced ..
- Audiometric analyses confirm a cochlear component, disproportional to age, in stapedial otosclerosisVedat Topsakal
Department of Otorhinolaryngology, Antwerp University Hospital UZA, Belgium
Otol Neurotol 27:781-7. 2006To report the preoperative audiometric profile of surgically confirmed otosclerosis.
- ["One shot" CO2 laser stapedotomy]S Jovanovic
Hals Nasen Ohren Klinik, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin
HNO 54:842-50. 2006..In order to further optimize the surgical technique with CO(2) laser in stapes surgery, a scanner system was used to obtain a footplate perforation of 0.5-0.6 mm with only one laser application ("one-shot" stapedotomy)...
- Video-oculography findings in patients with otosclerosisJuuso Kujala
Department of Otorhinolaryngology, Helsinki University Central Hospital, Helsinki, Finland
Otol Neurotol 26:1134-7. 2005..To evaluate the existence of vestibular irritation with video-oculography before and after stapes surgery and to examine whether there would be signs of specific end-organ irritation...
- [Surgical experience by 95 malformed stampedes and otosclerosis]Tongjia Leng
Department of Otolaryngology Head and Neck Surgery, Affiliated Beijing Tongren Hospital of Capital University of Medical Sciences, Beijing, 100730, China
Lin Chuang Er Bi Yan Hou Ke Za Zhi 19:9-11. 2005..To investigate the effect of stapes surgery for conductive hearing loss with intact tympanic membrane and eustachian tube...
- First experience with a new stapes clip piston in stapedotomyW Grolman
Department of Otorhinolaryngology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Otol Neurotol 26:595-8. 2005..a newly designed titanium-clip stapes piston prosthesis (the àWengen Clip Piston prosthesis) in patients with otosclerosis were evaluated. This new type of stapes piston was designed to avoid the crimping onto the incus in stapedotomy...
- Air and bone conduction change after stapedotomy and partial stapedectomy for otosclerosisNicola Quaranta
Otorhinolaryngology Clinic G Lugli, Otologic and Neurotologic Surgery, Department of Ophthalmology and Otorhinolaryngology, University of Bari, Italy
Otolaryngol Head Neck Surg 133:116-20. 2005The aim of this study was to analyze and compare the results obtained in otosclerosis patient undergoing stapedotomy and partial stapedectomy.
- Bilateral stapedectomy: association between first- and second-ear surgical findings and their effects on the second-ear outcomeNeville P Shine
Department of Otolaryngology Head and Neck Surgery, Royal Perth Hospital, Perth, Australia
Ann Otol Rhinol Laryngol 117:207-11. 2008We assessed the association between first-ear and second-ear surgical findings in patients undergoing second-ear stapedectomy for bilateral otosclerosis and the impact of such findings on the audiometric outcome of the second ear.
- Fixation of the stapes footplate in children: a clinical and temporal bone histopathologic studyEdgar Bachor
Department of Otolaryngology, SRH Zentralklinikum Suhl gGmbH, Suhl, Germany
Otol Neurotol 26:866-73. 2005..To clarify the anatomic characteristics, cause, and surgical outcomes relating to fixation of the stapes footplate in children...
- A new self-fixing and articulated malleus grip stapedectomy prosthesisRudolf Hausler
Department of ENT, Head and Neck Surgery, Inselspital, University of Bern, Bern, Switzerland
Adv Otorhinolaryngol 65:197-201. 2007..It appears that with the new Clip Piston MVP the previously difficult surgery of malleus-grip stapedectomy has become straight forward and technically simpler...
- Involvement of the incudostapedial joint anomaly in conductive deafnessMamoru Suzuki
Department of Otolaryngology, Tokyo Medical University, Tokyo, Japan
Acta Otolaryngol 128:515-9. 2008..We must be aware that the pathology of the congenital ossicular anomalies is variable and careful surgery is needed for hearing improvement...
- Bone conduction variation poststapedotomyLuca Moscillo
ENT Department S Maria delle Grazie Hospital Pozzuoli, Naples, Italy
Am J Otolaryngol 27:330-3. 2006..evaluated the variation in bone conduction auditory thresholds in patients undergoing surgical intervention for otosclerosis as part of our report on the use of surgery in patients with a small air-bone gap...
- [Laser stapedotomy--the modern solution of otosclerotic stapes fixation]Imre Gerlinger
Pecsi Tudomanyegyetem, Altalános Orvostudományi Kar Fül orr gégészeti és Fej nyaksebészeti Klinika Pécs Munkácsy M u 2 7621
Orv Hetil 148:2241-7. 2007..Nowadays not only stapedectomy and partial stapedectomy, but stapedotomy can also be considered a well established otological procedure...
- Retrospective analysis of outcomes after stapedotomy with implantation of a self-crimping Nitinol stapes prosthesisAbraham J Sorom
Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Rochester, MN 55905, USA
Otolaryngol Head Neck Surg 137:65-9. 2007..To review hearing results after implantation of a self-crimping stapes prosthesis...
- The influence of the footplate-perilymph interface on postoperative bone conductionWolfgang Arnold
Department of Otolaryngology, Head and Neck Surgery, Technical University of unich, Klinikum rechts der Isar, Munich, Germany
Adv Otorhinolaryngol 65:155-7. 2007....
- Stapedectomy versus stapedotomyPer Møller
Haukeland University Hospital, Bergen, Norway
Adv Otorhinolaryngol 65:169-73. 2007Four hundred and twelve consecutive stapes operations for otosclerosis performed by the author were analyzed. A fat wire stapedectomy prosthesis (Schuknecht) was used in 160 cases and a Fisch Teflon wire piston in 252 ears...
- Autogenic and xenogenic materials in stapes surgery: retrospective analysis of 350 casesMarcin Durko
Otosurgery Department, Medical University of Lodz, Lodz, Poland
Adv Otorhinolaryngol 65:179-83. 2007..Retrospective analysis of the postoperative hearing results in stapes surgery using autogenic materials versus xenogenic materials at the 12-month follow-up...
- Transient depression of inner ear function after stapedotomy: skeeter versus CO(2) laser techniqueT Somers
University ENT Department, Sint Augustinus Hospital, Wilrijk, Belgium
Adv Otorhinolaryngol 65:267-72. 2007Performing stapes surgery for otosclerosis is known to be potentially irreversibly harmful to the inner ear function in about 1% of the cases...
- Malleostapedotomy: the Marburg experienceC V Dalchow
Department of Otolaryngology, Head and Neck Surgery, Philipps University of Marburg, Marburg, Germany
Adv Otorhinolaryngol 65:215-21. 2007The surgical procedure for patients with otosclerosis routinely is incus stapedotomy. In case of otosclerosis with incus necrosis or a bony fixation of the malleus and incus, malleostapedotomy is performed.
- Stapes surgery in Japanese patients with osteogenesis imperfectaKatsumi Doi
Department of Otolaryngology and Sensory Organ Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
Adv Otorhinolaryngol 65:226-30. 2007..Hearing results following stapes surgery in patients with otosclerosis during the same time interval (n = 132) did not differ significantly...
- Stapes surgery in the elderlySalvatore Iurato
Centro di Otologia srl, Bari, Italy
Adv Otorhinolaryngol 65:231-6. 2007..Although the success rate, defined as a postoperative air-bone gap within 10 dB, was lower in the older group (71%) than in the younger group (92%), stapedectomy remains an effective surgical procedure also in the elderly...
- Distortion product otoacoustic emissions in otosclerosis: intraoperative findingsR Filipo
Department of Neurology and Otolaryngology, University La Sapienza, Rome, Italy
Adv Otorhinolaryngol 65:133-6. 2007The aim of the study was to investigate changes in middle ear dynamic characteristics caused by both otosclerosis and stapes surgery (platinotomy, prosthesis positioning, ossicular chain maneuver) and to evaluate distortion product ..
- Audiological evaluation of patients with otosclerosisRudolf Probst
Department of Otorhinolaryngology, University Hospital, Basel, Switzerland
Adv Otorhinolaryngol 65:119-26. 2007Even though the diagnosis of otosclerosis is confirmed definitively during surgery, preoperative diagnosis and determination of the indication for surgery are made based on audiological evaluation...
- [Analysis of results of stapedotomy in patients with obliterative otosclerosis]Tatiana Gierek
Katedra i Klinika Laryngologii Sl AM w Katowicach
Otolaryngol Pol 60:377-83. 2006In obliterative type of otosclerosis the stapes footplate is greatly thickened and diffusely replaced by a massive otosclerotic masses that fill in the oval window niche, often annular ligament cannot be visualized...
- Very far-advanced otosclerosis: stapedotomy or cochlear implantationMarie Noelle Calmels
Department of Otology Neurotology and Skull Base Surgery, Purpan Hospital, Toulouse, CHU Toulouse, France
Acta Otolaryngol 127:574-8. 2007..This can justify our decision to propose stapedotomy at the initial treatment in patients with very far-advanced otosclerosis. In cases of hearing failure after stapes surgery, cochlear implantation is an option.
- Hearing results after stapedotomy: role of the prosthesis diameterMaria Raffaella Marchese
Institute of Otorhinolaryngology, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Roma, Italy
Audiol Neurootol 12:221-5. 2007To evaluate the functional results obtained after stapedotomy in patients affected by otosclerosis, according to the prosthesis diameter.
- Effect of cochlear reserve on postoperative outcome in otosclerosisBulent Satar
Department of Otolaryngology, Head and Neck Surgery, Gulhane Military Medical Academy, GATA KBB Anabilim Dali, Etlik, Ankara, Turkey
Eur Arch Otorhinolaryngol 264:489-93. 2007Patients with elevated bone conduction (BC) thresholds are not considered a good candidate for otosclerosis surgery. Sometimes, it might be difficult to decide to operate these patients considering relatively poor cochlear function...
- Role of stapes surgery in improving hearing loss caused by otosclerosisM R Marchese
Institute of Otorhinolaryngology, Policlinico A Gemelli, Universita Cattolica del Sacro Cuore, Rome, Italy
J Laryngol Otol 121:438-43. 2007..of small fenestra stapedotomy with that of total stapedectomy in improving hearing in patients affected by otosclerosis. Three hundred and fifty-seven consecutive ears, in 265 patients affected by otosclerosis, underwent surgery...
- [Temporary sensory hearing deficits after ear surgery--a retrospective analysis]B Schick
Hals Nasen Ohrenklinik, Kopf und Halschirurgie, Friedrich Alexander Universitat Erlangen Nurnberg
Laryngorhinootologie 86:200-5. 2007..Temporary and persistent threshold shifts can occur after ear surgery. So far, only few studies deal with temporary sensory hearing deficits after ear surgery...
- Stapedotomy with microdrill or carbon dioxide laser: influence on inner ear functionThomas Somers
Department of Otorhinolaryngology, Saint Augustine Hospital, Antwerp, Belgium
Ann Otol Rhinol Laryngol 115:880-5; discussion 886. 2006A prospective randomized audiological analysis of 336 otosclerosis operations was conducted to compare the evolution of bone conduction thresholds after primary stapedotomy with two different techniques to open the footplate: microdrill ..
- Revision stapes surgery: retrospective analysis of surgical findings in a series of 21 otosclerosis patientsMarcin Durko
Department of Otosurgery, Medical University of Lodz, Lodz, Poland
Adv Otorhinolaryngol 65:273-7. 2007Retrospective analysis of surgical findings in revision stapes surgery in a group of 21 otosclerosis patients qualified for the secondary procedure at the Otosurgery Department of the Medical University of Lodz, Poland, from 1980 to 2002.
- Technical and clinical aspects of 'one-shot' CO(2) laser stapedotomyS Jovanovic
ENT Department, Charite University Medical Center, Campus Benjamin Franklin, Berlin, Germany
Adv Otorhinolaryngol 65:255-66. 2007..In order to further optimize the surgical technique with the CO(2) laser in stapes surgery, a scanner system was used to obtain a footplate perforation of 0.5-0.6mm with only one laser application ('one-shot' stapedotomy)...
- Retrospective analysis of early postoperative hearing results obtained after stapedotomy with implantation of a new titanium stapes prosthesisC L Zuur
Department of Otolaryngology Head and Neck Surgery, Academical Medical Center, University of Amsterdam, The Netherlands
Otol Neurotol 24:863-7. 2003To evaluate the early postoperative hearing results of a new titanium stapes prosthesis (K-Piston) implanted in patients with otosclerosis.
- Revision stapes surgery: the malleus to oval window wire-piston techniqueDarius Kohan
Department of Otolaryngology, New York University, School of Medicine, New York, New York, USA
Laryngoscope 113:1520-4. 2003..To determine the effectiveness of the malleus to oval window wire-piston revision stapes surgery technique...
- Predictive factors in pediatric stapedectomyD Bradley Welling
Department of Otolaryngology, The Ohio State University, Columbus, USA
Laryngoscope 113:1515-9. 2003..The objective of the study was to investigate predictive factors in the postoperative hearing outcomes in pediatric stapedectomy...
- Partial promontory technique in stapedotomy cases with narrow nicheMichelle M Inserra
California Ear Institute, Palo Alto 94303, USA
Otol Neurotol 25:443-6. 2004..The objective of this study was to examine clinical and audiometric outcomes of a laser partial promontory technique in stapedotomy cases with a narrow oval window niche...
- Fixation of the anterior mallear ligament: diagnosis and consequences for hearing results in stapes surgeryAlexander Huber
Department of Otorhinolaryngology Head and Neck Surgery, University Hospital of Zurich, Zurich, Switzerland
Ann Otol Rhinol Laryngol 112:348-55. 2003..Untreated anterior mallear ligament fixation produced a persistent air-bone gap of approximately 10 dB after stapedioplasty...
- Vein versus tragal perichondrium in stapedotomySebastien Schmerber
University Department of Otorhinolaryngology, Grenoble Hospital, Grenoble, France
Otol Neurotol 25:694-8. 2004To assess, in otosclerosis surgery, whether the vein or the tragal perichondrium in stapedotomy with interposition yields the better long-term hearing outcome.
- [Change in otosclerosis presentation over two decades]Marcin Szymanski
Klinika Otolaryngologii AM w Lublinie
Otolaryngol Pol 56:557-60. 2002Presentation of otosclerosis in eighties and nineties was compared on the basis of analysis of patients' documentation...
- [Glasgow Benefit Plot for evaluation of stapedectomy result]Marcin Szymanski
Klinika Otolaryngologii AM w Lublinie
Otolaryngol Pol 57:403-6. 2003..Evaluation of hearing tests using the Glasgow Benefit Plot enables to evaluate patient's hearing disability and to predict possible benefit from surgery for individual cases...
- Hearing results after stapedotomy with a nitinol piston prosthesisKevin D Brown
Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, USA
Arch Otolaryngol Head Neck Surg 133:758-62. 2007To compare the hearing results in patients with otosclerosis who underwent a stapedotomy with either a platinum wire prosthesis or a commercially available, heat-activated nitinol stapes piston prosthesis.
- [Stability of auditory thresholds during the first 5 weeks after stapedectomy]G L Morín Murillo
Servicio de Otorrinolaringologia, Hospital General del Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico D F
Acta Otorrinolaringol Esp 53:321-5. 2002..performed every week during the first month post-stapedectomy, audiometry was performed to 21 patients with otosclerosis (mean age 37.8 years, S.D. 9...
- Efficacy of evaluation of audiometric results after stapes surgery in otosclerosis. II. A method for reporting results from individual casesA J De Bruijn
Department of Otorhinolaryngology and Head and Neck Surgery and the Department of Audiology (Professor Dreschler, Academic Medical Center, University of Amsterdam
Otolaryngol Head Neck Surg 124:84-9. 2001..This results in 2 plots, which we called the Amsterdam Hearing Evaluation Plots. Audiometric data from 451 stapes operations were used to demonstrate the use of the Amsterdam Hearing Evaluation Plots...
- Efficacy of evaluation of audiometric results after stapes surgery in otosclerosis. I. The effects of using different audiologic parameters and criteria on success ratesA J De Bruijn
Department of Otorhinolaryngology-Head and Neck Surgery, Academic Medical Center, University of Amsterdam, The Netherlands
Otolaryngol Head Neck Surg 124:76-83. 2001..Also, choice of preoperative or postoperative BC in computing postoperative ABGs had a significant effect on the mean postoperative ABG levels, showing more favorable results with the use of preoperative BC thresholds...
- Stapedotomy for tympanosclerotic stapes fixation: is it safe and efficient? A review of 68 casesRobert Vincent
Jean Causse Ear Clinic, Traverse de Béziers, Clombiers, France
Otol Neurotol 23:866-72. 2002..The procedure is traditionally considered to carry a high risk of postoperative sensorineural hearing loss. The aim of this study was to report the hearing results in surgically treated cases of stapes fixation...
- [Identification of human papilloma viruses (HPV) in inflammatory states and ear neoplasms]Bogdan Rydzewski
Oddział Otolaryngologiczny Szpitala im F Raszei w Poznaniu
Otolaryngol Pol 61:137-41. 2007..The control group consisted of 5 patients operated on: otosclerosis--4 cases and post-traumatic tympanic membrane perforation--1 case...
- A novel RNA-splicing mutation in COL1A1 gene causing osteogenesis imperfecta type I in a Chinese familyXin Yi Xia
Institute of Laboratory Medicine, Jinling Hospital, Nanjing University School of Medicine, 305 East Zhongshan Road, Nanjing 210002, PR China
Clin Chim Acta 398:148-51. 2008..are osteoporosis with abnormal fragility of the skeleton, blue sclera, dentinogenesis imperfecta, and premature otosclerosis. The presence of two of these abnormalities confirms the diagnosis...
- Non-syndromal round window atresia: an autosomal dominant genetic disorder with variable penetrance?A Borrmann
Department of Otolaryngology Head and Neck Surgery, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
Eur Arch Otorhinolaryngol 264:1103-8. 2007..syndromal anomalies such as mandibulofacial dysostosis, Mondini type anomalies or cretinism, or with extensive otosclerosis. Non-syndromal round window atresia is extremely rare and until today there is no proof whether non-syndromal ..
- Histopathology of nonotosclerotic stapes fixationsTamás Karosi
Department of Otolaryngology Head and Neck Surgery, University Medical School of Debrecen, Debrecen, Hungary
Otol Neurotol 30:1058-66. 2009..Different diseases without exact histopathologic classification can cause stapes ankylosis...
- [Progressive sensorineural hearing loss in cochlear otosclerosis]S Sellari Franceschini
Dipartimento di Neuroscienze,
Acta Otorhinolaryngol Ital 18:59-65. 1998b>Otosclerosis is a bone dysplasia limited to the otic capsule causing abnormal resorption and redeposition of bone...
- Safety of the erbium:yttrium-aluminum-garnet laser in stapes surgery in otosclerosisT Keck
Department of Otorhinolaryngology, University of Ulm, Ulm, Germany
Otol Neurotol 23:21-4. 2002The purpose of this study was to present early and late bone-conduction hearing thresholds and data about cochlear and vestibular disturbances in patients after erbium:yttrium-aluminum-garnet (Er:YAG) laser stapedotomy in otosclerosis.
- [Malleostapedotomy in stapes surgery for otosclerosis with malleus/incus mobility disorder]Peina Wu
Department of Otorhinolaryngology Head and Neck Surgery, Guangdong Provincial People s Hospital, Guangzhou, 510080, China
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 21:791-3. 2007To evaluate the feasibility, safety and effectiveness of malleostapedotomy based on malleus-oval window technique in otosclerosis with malleus/incus mobility disorder.
- Hearing sensitivity and bone mineral density in older adults: the Health, Aging and Body Composition StudyElizabeth P Helzner
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
Osteoporos Int 16:1675-82. 2005..of the cochlear capsule has been associated with hearing loss in those with Paget's disease of the bone and otosclerosis. Osteoporosis may also result in cochlear capsule demineralization...
- Reconstruction of the entire ossicular conduction mechanismAlex Battaglia
Department of Head Neck Surgery, Southern California Kaiser Permanente Medical Group, 3033 Bunker Hill Street, San Diego, CA 92109, USA
Laryngoscope 113:654-8. 2003..This situation may occur in the presence of severe tympanosclerosis, otosclerosis, congenital ossicular malformations, and revision surgery for either stapedectomy or chronic ear disease...
- Study of a temporal bone of Homo heildelbergensisRafael Urquiza
Faculty of Medicine, University of Granada, Granada, Spain
Acta Otolaryngol 125:457-63. 2005..It also strongly suggests that Hh individuals were predisposed to develop certain pathologies of the labyrinth capsule associated with bipedalism, in particular otosclerosis.
- [Detection of humoral immune response to inner ear proteins in patients with sensorineural hearing loss]A Naumann
Klinik und Poliklinik Fur Hals, Nasen und Ohrenkranke der Ludwig Maximilians Universität München
Laryngorhinootologie 80:237-44. 2001..The aim of this study is the investigation of humoral immune reactivity to inner ear components in patients with sensorineural hearing loss...
- Drug-eluting Stapes Prosthesis for the Prevention of Sensorineural Hearing LossMichael J McKenna; Fiscal Year: 2010DESCRIPTION (provided by applicant): Otosclerosis is a disease of the otic capsule that is among the most common causes of acquired hearing loss...
- Development of a laser holography otoscope for diagnosis in the clinicJOHN ROSOWSKI; Fiscal Year: 2009..g. otosclerosis), trauma to the head or ear and pathologic third-windows of the inner ear...
- Middle-ear Mechanics in Normal and Pathological EarsSAUMIL MERCHANT; Fiscal Year: 2003..Middle-ear diseases such as chronic otitis media and otosclerosis, which affect over 10 million people in the US, are common causes of significant conductive hearing loss...
- Middle-ear Mechanics in Normal and Pathological EarsSAUMIL MERCHANT; Fiscal Year: 2001..Middle-ear diseases such as chronic otitis media and otosclerosis, which affect over 10 million people in the US, are common causes of significant conductive hearing loss...
- Middle-ear Mechanics in Normal and Pathological EarsSAUMIL MERCHANT; Fiscal Year: 2004..Middle-ear diseases such as chronic otitis media and otosclerosis, which affect over 10 million people in the US, are common causes of significant conductive hearing loss...
- Middle-ear Mechanics in Normal and Pathological EarsSAUMIL MERCHANT; Fiscal Year: 2002
- Middle-ear Mechanics in Normal and Pathological EarsSAUMIL MERCHANT; Fiscal Year: 2005
- Development of a laser holography otoscope for diagnosis in the clinicJohn J Rosowski; Fiscal Year: 2010..g. otosclerosis), trauma to the head or ear and pathologic third-windows of the inner ear...
- HUMAN MIDDLE EAR--FORWARD AND REVERSE SOUND TRANSMISSIONSunil Puria; Fiscal Year: 2000..Examples of middle-ear modifications include fixation of the stapes (as in otosclerosis), fixation of the incus-malleus head, and eardrum perforations...
- HUMAN MIDDLE EAR--FORWARD AND REVERSE SOUND TRANSMISSIONSunil Puria; Fiscal Year: 1999..Examples of middle-ear modifications include fixation of the stapes (as in otosclerosis), fixation of the incus-malleus head, and eardrum perforations...
- HUMAN MIDDLE EAR--FORWARD AND REVERSE SOUND TRANSMISSIONSunil Puria; Fiscal Year: 2001..Examples of middle-ear modifications include fixation of the stapes (as in otosclerosis), fixation of the incus-malleus head, and eardrum perforations...
- HUMAN MIDDLE EAR--FORWARD AND REVERSE SOUND TRANSMISSIONSunil Puria; Fiscal Year: 2002
- MECHANISMS OF TISSUE DESTRUCTION IN THE MIDDLE EARRICHARD CHOLE; Fiscal Year: 1990..a major cause of hearing loss in chronic otitis media, with and without cholesteatoma and in active lesions of otosclerosis. This proposal is directed toward an understanding of the mechanisms controlling these localized remodeling ..
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2000..Recently, the osteogenesis imperfecta (OI) associated gene COL 1A1 has been implicated in otosclerosis. The hypothesis is that otosclerosis represents a minor variant of OI and possesses a similar dysfunction in ..
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2000..Recently, the osteogenesis imperfecta (OI) associated gene COL 1A1 has been implicated in otosclerosis. The hypothesis is that otosclerosis represents a minor variant of OI and possesses a similar dysfunction in ..
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 1999..Recently, the osteogenesis imperfecta (OI) associated gene COL 1A1 has been implicated in otosclerosis. The hypothesis is that otosclerosis represents a minor variant of OI and possesses a similar dysfunction in ..
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2001
- COMPACT LASER INSTRUMENTS FOR OTOLOGIC SURGERYJEFFREY PIERCE; Fiscal Year: 2007..The compact diode pumped fiber laser system will be primarily directed to the treatment of otosclerosis via laser stapes surgery...
- COMPACT LASER INSTRUMENTS FOR OTOLOGIC SURGERYJEFFREY PIERCE; Fiscal Year: 2006..The compact diode pumped fiber laser system will be primarily directed to the treatment of otosclerosis via laser stapes surgery...
- BIOMARKERS FOR TOTAL BODY BURDEN OF FLUORIDEThomas Shearer; Fiscal Year: 2003..bone cancer, uterine cancer, fertility rates, testosterone levels, gastro-duodenal manifestations, and otosclerosis. The majority of studies evaluating the impact of fluoridation on chronic health conditions, however, have been ..
- BIOMARKERS FOR TOTAL BODY BURDEN OF FLUORIDEKirsten Lampi; Fiscal Year: 2004..bone cancer, uterine cancer, fertility rates, testosterone levels, gastro-duodenal manifestations, and otosclerosis. The majority of studies evaluating the impact of fluoridation on chronic health conditions, however, have been ..
- COCHLEAR HOMEOSTASISJoe Adams; Fiscal Year: 2003..hearing loss in a variety of common, but poorly understood, otological disorders such as labyrinthitis, otosclerosis, genetic hearing losses involving gap junction proteins, and immune-mediated hearing loss...
- COCHLEAR HOMEOSTASISJoe Adams; Fiscal Year: 2002..hearing loss in a variety of common, but poorly understood, otological disorders such as labyrinthitis, otosclerosis, genetic hearing losses involving gap junction proteins, and immune-mediated hearing loss...
- COCHLEAR HOMEOSTASISJoe Adams; Fiscal Year: 1999..hearing loss in a variety of common, but poorly understood, otological disorders such as labyrinthitis, otosclerosis, genetic hearing losses involving gap junction proteins, and immune-mediated hearing loss...
- COCHLEAR HOMEOSTASISJoe Adams; Fiscal Year: 2001
- COCHLEAR HOMEOSTASISJoe Adams; Fiscal Year: 2000
- Otosclerosis-A Molecular Genetic StudyRichard Smith; Fiscal Year: 2002Among white adults, otosclerosis is the single most common cause of hearing impairment...
- Otosclerosis-A Molecular Genetic StudyRichard Smith; Fiscal Year: 2006Among white adults, otosclerosis is the single most common cause of hearing impairment...
- Otosclerosis-A Molecular Genetic StudyRichard Smith; Fiscal Year: 2005Among white adults, otosclerosis is the single most common cause of hearing impairment...
- Otosclerosis-A Molecular Genetic StudyRichard Smith; Fiscal Year: 2003Among white adults, otosclerosis is the single most common cause of hearing impairment...
- Otosclerosis-A Molecular Genetic StudyRichard Smith; Fiscal Year: 2004Among white adults, otosclerosis is the single most common cause of hearing impairment...
- MOLECULAR BASIS OF INHERITANCE IN OTOSCLEROSISMichael McKenna; Fiscal Year: 1992b>Otosclerosis has an unequivocal hereditary predisposition although the exact nature of the genetic transmission has not been delineated...
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2004The goal of the proposed investigation is to achieve a better understanding of the molecular pathology of otosclerosis and ultimately develop better forms of treatment and prevention...
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2005The goal of the proposed investigation is to achieve a better understanding of the molecular pathology of otosclerosis and ultimately develop better forms of treatment and prevention...
- MOLECULAR BASIS OF OTOPATHOLOGYMichael McKenna; Fiscal Year: 2003The goal of the proposed investigation is to achieve a better understanding of the molecular pathology of otosclerosis and ultimately develop better forms of treatment and prevention...
- SNR-loss in hearing impaired earsJont Allen; Fiscal Year: 2008..answer the questions: "Specifically which perceptual consonant features are not audible to each hearing impaired listener?", "How does this audibility and confusability change as a function of the background noise and amplification?" ..
- SYMPOSIA FOR ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYElizabeth Keithley; Fiscal Year: 2008..abstract_text> ..
- SYMPOSIA FOR ASSOCIATION FOR RESEARCH IN OTOLARYNGOLOGYElizabeth Keithley; Fiscal Year: 2007..abstract_text> ..
- INNER EAR IMMUNE RESPONSESElizabeth Keithley; Fiscal Year: 2001..Such knowledge will enable clinicians to improve the treatments administered to patients who experience the unfortunate and potentially devastating trauma of rapidly progressing sensorineural hearing loss. ..
- INNER EAR IMMUNE RESPONSESElizabeth Keithley; Fiscal Year: 2002..Such knowledge will enable clinicians to improve the treatments administered to patients who experience the unfortunate and potentially devastating trauma of rapidly progressing sensorineural hearing loss. ..
- INNER EAR IMMUNE RESPONSESElizabeth Keithley; Fiscal Year: 2000..Such knowledge will enable clinicians to improve the treatments administered to patients who experience the unfortunate and potentially devastating trauma of rapidly progressing sensorineural hearing loss. ..
- The Effects of Resveratrol on PresbyacusisMichael Seidman; Fiscal Year: 2004..Furthermore, these data will provide novel strategies to impart greater wellness in the elderly population and perhaps have a positive effect on health care expenses. ..
- Herpesviruses in Vestibular NeuritisJEFFREY VRABEC; Fiscal Year: 2003..This information can help determine why some individuals with latent virus in the vestibular ganglion develop clinical symptoms due to reactivation and some do not. ..