short bowel syndrome

Summary

Summary: A malabsorption syndrome resulting from extensive operative resection of the SMALL INTESTINE, the absorptive region of the GASTROINTESTINAL TRACT.

Top Publications

  1. ncbi Guidelines for management of patients with a short bowel
    J Nightingale
    St Mark's Hospital, Harrow HA1 3UJ, UK
    Gut 55:iv1-12. 2006
  2. ncbi Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome
    B Messing
    Department of Hepatogastroenterology, INSERM Unité 290, Hôpital Lariboisière Saint Lazare, Paris, France
    Gastroenterology 117:1043-50. 1999
  3. ncbi Advances in the management of short bowel syndrome
    Christian Jackson
    Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Curr Gastroenterol Rep 7:373-8. 2005
  4. ncbi Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS
    Conrad R Cole
    Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Drive, Atlanta, GA 30322, USA
    Curr Gastroenterol Rep 9:456-62. 2007
  5. ncbi Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon
    P B Jeppesen
    Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, Denmark
    Gut 47:370-6. 2000
  6. ncbi Synovial lipomatosis (lipoma arborescens) affecting multiple joints in a patient with congenital short bowel syndrome
    Chokkalingam Siva
    Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Rheumatol 29:1088-92. 2002
  7. ncbi Etiology and initial management of short bowel syndrome
    Alan L Buchman
    Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Gastroenterology 130:S5-S15. 2006
  8. ncbi Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
    P B Jeppesen
    Department of Gastroenterology CA 2121, Rigshospitalet, Copenhagen, Denmark
    Gut 60:902-14. 2011
  9. ncbi Some new insights in intestinal failure-associated liver disease
    Olivier Goulet
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, Intestinal Failure Rehabilitation Center, Hospital Necker Enfants Malades, University of Paris Descartes, 75743 Paris Cedex 15, Paris, France
    Curr Opin Organ Transplant 14:256-61. 2009
  10. ncbi Morphological adaptation with preserved proliferation/transporter content in the colon of patients with short bowel syndrome
    Francisca Joly
    Service de Gastroentérologie et Assistance Nutritive, Pôle des Maladies de l Appareil Digestif, Hopital Beaujon, Clichy, France
    Am J Physiol Gastrointest Liver Physiol 297:G116-23. 2009

Research Grants

  1. AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTION
    HARRY SAX; Fiscal Year: 2004
  2. NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATION
    Marc Levin; Fiscal Year: 2009
  3. Short-Chain Fatty Acid Enhanced Intestinal Adaptation
    KELLY TAPPENDEN; Fiscal Year: 2006
  4. Mechanisms of Intestinal Stem Cell Expansion Following Resection
    Michael A Helmrath; Fiscal Year: 2009
  5. Mechanisms of Intestinal Stem Cell Expansion Following Resection
    Michael A Helmrath; Fiscal Year: 2010
  6. TOTAL PARENTERAL NUTRITION AND INTESTINAL ADAPTION
    Denise Ney; Fiscal Year: 2006
  7. Novel Polymers for Tissue Engineering
    ROBERT SAMUEL LANGER; Fiscal Year: 2010
  8. NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATION
    Marc Levin; Fiscal Year: 2007
  9. Enterocyte Apoptosis after Intestinal Resection
    Brad Warner; Fiscal Year: 2006
  10. Parenteral Nutrition: Intestinal Metabolism/Adaptation
    Denise Ney; Fiscal Year: 2009

Detail Information

Publications226 found, 100 shown here

  1. ncbi Guidelines for management of patients with a short bowel
    J Nightingale
    St Mark's Hospital, Harrow HA1 3UJ, UK
    Gut 55:iv1-12. 2006
  2. ncbi Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndrome
    B Messing
    Department of Hepatogastroenterology, INSERM Unité 290, Hôpital Lariboisière Saint Lazare, Paris, France
    Gastroenterology 117:1043-50. 1999
    The short bowel syndrome (SBS) may be associated with either transient or permanent intestinal failure, presently treated by parenteral nutrition (PN)...
  3. ncbi Advances in the management of short bowel syndrome
    Christian Jackson
    Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Curr Gastroenterol Rep 7:373-8. 2005
    b>Short bowel syndrome (SBS) is the predominant cause of intestinal failure and is thus associated with a high degree of morbidity and mortality. One of the reasons this occurs is the dramatic reduction in nutrient absorptive capacity...
  4. ncbi Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBS
    Conrad R Cole
    Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Drive, Atlanta, GA 30322, USA
    Curr Gastroenterol Rep 9:456-62. 2007
    Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria...
  5. ncbi Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon
    P B Jeppesen
    Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, Denmark
    Gut 47:370-6. 2000
    ..Ileum resected short bowel patients with a preserved colon show evidence of functional adaptation and have normal gastric emptying...
  6. ncbi Synovial lipomatosis (lipoma arborescens) affecting multiple joints in a patient with congenital short bowel syndrome
    Chokkalingam Siva
    Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
    J Rheumatol 29:1088-92. 2002
    ..The co-occurrence with congenital short bowel syndrome may have etiological implications for this disorder of inappropriate fat deposition.
  7. ncbi Etiology and initial management of short bowel syndrome
    Alan L Buchman
    Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Gastroenterology 130:S5-S15. 2006
  8. ncbi Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndrome
    P B Jeppesen
    Department of Gastroenterology CA 2121, Rigshospitalet, Copenhagen, Denmark
    Gut 60:902-14. 2011
    ..reducing gastric emptying and secretion, thereby increasing fluid and nutrient absorption in patients with short bowel syndrome (SBS)...
  9. ncbi Some new insights in intestinal failure-associated liver disease
    Olivier Goulet
    Department of Pediatric Gastroenterology, Hepatology and Nutrition, Intestinal Failure Rehabilitation Center, Hospital Necker Enfants Malades, University of Paris Descartes, 75743 Paris Cedex 15, Paris, France
    Curr Opin Organ Transplant 14:256-61. 2009
    ..To point new insights in the cholestasis that is a complication of both intestinal failure and parenteral nutrition. View on liver disease has recently evolved with the onset of fish oil-based intravenous lipid emulsions (ILE)...
  10. ncbi Morphological adaptation with preserved proliferation/transporter content in the colon of patients with short bowel syndrome
    Francisca Joly
    Service de Gastroentérologie et Assistance Nutritive, Pôle des Maladies de l Appareil Digestif, Hopital Beaujon, Clichy, France
    Am J Physiol Gastrointest Liver Physiol 297:G116-23. 2009
    In short bowel syndrome (SBS), although a remaining colon improves patient outcome, there is no direct evidence of a mucosal colonic adaptation in humans...
  11. ncbi Intestinal rehabilitation and the short bowel syndrome: part 2
    John K DiBaise
    Department of Internal Medicine, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE 68198-2000, USA
    Am J Gastroenterol 99:1823-32. 2004
    The management of patients with intestinal failure due to short bowel syndrome is complex, requiring a comprehensive approach that frequently necessitates long-term, if not life-long, use of parenteral nutrition...
  12. ncbi The effect of growth hormone supplementation on late nutritional independence in pediatric patients with short bowel syndrome
    Alan P Ladd
    Section of Pediatric Surgery, Department of Surgery, Indiana University School of Medicine and Riley Children s Hospital, Indianapolis, IN 46202, USA
    J Pediatr Surg 40:442-5. 2005
    The use of growth hormone (GH) supplementation for intestinal adaptation among adult patients with short bowel syndrome (SBS) has provided mixed results. This report examines the effect of GH supplementation on SBS in pediatric patients.
  13. ncbi Teduglutide for the treatment of short bowel syndrome
    Marcus Ferrone
    Department of Pharmacy Nutrition Mayo Clinic St Luke s Hospital, Jacksonville, FL 32216, USA
    Ann Pharmacother 40:1105-9. 2006
    To summarize the pharmacology, development, and clinical application of teduglutide (ALX-0600), a glucagon-like peptide-2 (GLP-2) analog for the treatment of short bowel syndrome (SBS).
  14. ncbi Gastrocolocutaneous fistula in a child with congenital short bowel syndrome: a rare complication of percutaneous endoscopic gastrostomy
    Yun Chen
    Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    J Formos Med Assoc 103:306-10. 2004
    ..We report a case of this complication in a 2-year-old boy with congenital short bowel syndrome with dilated bowel loops who underwent PEG insertion...
  15. ncbi Effect of recombinant human growth hormone and enteral nutrition on short bowel syndrome
    Zhu Weiming
    From the Department of General Surgery, Jinling Hospital, Nanjing, Jiangsu, China
    JPEN J Parenter Enteral Nutr 28:377-81. 2004
    ..rhGH), nutrition support, glutamine, and dietary fiber, promotes intestinal adaptation in patients with short bowel syndrome. The aim of the current study was to determine if enteral nutrition and rhGH are effective in weaning short ..
  16. ncbi Glucagon-like peptide-2: update of the recent clinical trials
    Palle Bekker Jeppesen
    Department of Medicine, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
    Gastroenterology 130:S127-31. 2006
    ..In this respect, glucagon-like peptide 2 (GLP-2) has received attention. In this review, the nature of the short bowel syndrome is described, and the antisecretory, transit-modulating, but also intestinotrophic effects of GLP-2 are ..
  17. ncbi Rehabilitation therapy for short bowel syndrome
    Weiming Zhu
    Department of General Surgery, Jinling Hospital, Clinical School of Nanjing University, Nanjing 210002, China
    Chin Med J (Engl) 115:776-8. 2002
    To investigate the effect of rehabilitation therapy for short bowel syndrome on patient nutritional status and intestinal adaptation.
  18. ncbi Intestinal permeability and effects of Lactobacillus rhamnosus therapy in children with short bowel syndrome
    Timothy A Sentongo
    Division of Gastroenterology, Hepatology and Nutrition, University of Chicago, Comer Children s Hospital, Chicago, IL 60637, USA
    J Pediatr Gastroenterol Nutr 46:41-7. 2008
    The present study was conducted to investigate the effects of Lactobacillus rhamnosus (also known as LGG) on intestinal permeability (IP) in children with short bowel syndrome (SBS).
  19. ncbi Serial transverse enteroplasty (STEP): a novel bowel lengthening procedure
    Heung Bae Kim
    Department of Surgery, Children's Hospital and Harvard Medical School, and Harvard Center for Minimally Invasive Surgery, Boston, Massachusetts 02115, USA
    J Pediatr Surg 38:425-9. 2003
    BACKGROUND/PURPOSE: Bowel lengthening may be beneficial for children with short bowel syndrome. However, current techniques require at least one intestinal anastomosis and place the mesenteric blood supply at risk...
  20. ncbi Mesenteric thrombosis causing short bowel syndrome in nephrotic syndrome
    Tim Ulinski
    Department of Pediatric Nephrology, , 26 avenue du Dr. Arnold-Netter, 75571 Paris Cedex 12, France
    Pediatr Nephrol 18:1295-7. 2003
    ..Oral cyclosporin A (CyA) was initiated for long-term treatment. Due to a short bowel syndrome with severe malabsorption, even oral administration of 22...
  21. ncbi Surgical approaches to improving intestinal function in the short-bowel syndrome
    J S Thompson
    Department of Surgery, University of Nebraska Medical Center, Omaha Veterans Affairs Medical Center, USA
    Arch Surg 134:706-9; discussion 709-11. 1999
    ..Nontransplantation surgical approaches to improve intestinal function in patients with the short-bowel syndrome have a satisfactory outcome in selected patients...
  22. ncbi Postoperative short bowel syndrome
    Jon S Thompson
    Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198-3280, USA
    J Am Coll Surg 201:85-9. 2005
    BACKGROUND: Unanticipated massive resection after intraabdominal procedures is an increasing cause of short bowel syndrome (SBS). Our aim was to determine the frequency and potential mechanisms of postoperative SBS...
  23. ncbi Clinical significance of GLP-2 in short-bowel syndrome
    P B Jeppesen
    Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Nutr 133:3721-4. 2003
    ....
  24. ncbi Comparison of massive vs. repeated resection leading to short bowel syndrome
    J S Thompson
    Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198 3280, USA
    J Gastrointest Surg 4:101-4. 2000
    b>Short bowel syndrome can result from either a single massive intestinal resection or repeated lesser resections, which might have prognostic implications...
  25. ncbi AGA technical review on short bowel syndrome and intestinal transplantation
    Alan L Buchman
    Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
    Gastroenterology 124:1111-34. 2003
  26. ncbi Short bowel syndrome: epidemiology and etiology
    Paul W Wales
    Group for Improvement of Intestinal Function and Treatment GIFT, Hospital for Sick Children, Toronto, Ontario, Canada
    Semin Pediatr Surg 19:3-9. 2010
    Pediatric short bowel syndrome (SBS) is most commonly caused by congenital or acquired conditions of the newborn...
  27. ncbi Citrulline blood levels as indicators of residual intestinal absorption in patients with short bowel syndrome
    Lidia Santarpia
    Dipartimento di Medicina Clinica e Sperimentale, Universita di Napoli Federico II, Napoli, Italy
    Ann Nutr Metab 53:137-42. 2008
    ..We studied 25 patients with short bowel syndrome (SBS) after at least 18 months since last digestive circuit modification; 24 of them were again evaluated 1 ..
  28. ncbi Multiple micronutrient deficiencies in a child with short bowel syndrome and normal somatic growth
    Debora Duro
    Division of Gastroenterology and Nutrition, Children's Hospital Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 46:461-4. 2008
  29. ncbi Intestinal rehabilitation and the short bowel syndrome: part 1
    John K DiBaise
    Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198-2000, USA
    Am J Gastroenterol 99:1386-95. 2004
    The management of patients with intestinal failure due to short bowel syndrome (SBS) is complex, requiring a comprehensive approach that frequently necessitates long-term, if not life-long, use of parenteral nutrition (PN)...
  30. ncbi Congenital short bowel syndrome: a case report and review of the literature
    Mohammed Hasosah
    University of British Columbia, Vancouver, Canada
    Can J Gastroenterol 22:71-4. 2008
    Congenital short bowel syndrome (SBS) is a rare condition of the newborn, with several reports demonstrating high mortality. A six-week-old boy presented with chronic diarrhea and failure to thrive...
  31. ncbi Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colon
    P B Jeppesen
    Department of Medicine, Section of Gastroenterology, Rigshospitalet, University Hospital of Copenhagen, Denmark
    Gastroenterology 120:806-15. 2001
    ..5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2...
  32. ncbi Immunonutritional effects during synbiotics therapy in pediatric patients with short bowel syndrome
    Keiichi Uchida
    Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Edobashi 2 174, Tsu, Mie, 514 0064, Japan
    Pediatr Surg Int 23:243-8. 2007
    The aim of this study was to evaluate the effects of synbiotic therapy in patients with short bowel syndrome (SBS)...
  33. ncbi Plasma ghrelin levels in patients with short bowel syndrome
    Michal Krsek
    3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
    Endocr Res 28:27-33. 2002
    ..This study was aimed to investigate the changes in plasma ghrelin levels in patients with short bowel syndrome. Twenty-four patients with malnutrition due to short bowel syndrome and eleven healthy controls were ..
  34. ncbi Short bowel syndrome following bariatric surgical procedures
    Corrigan L McBride
    Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE 68198 3280, USA
    Am J Surg 192:828-32. 2006
    b>Short bowel syndrome (SBS) is a potential postoperative complication that is occurring with increasing frequency after bariatric procedures (BP)...
  35. ncbi Short bowel syndrome and intestinal failure: consensus definitions and overview
    Stephen J D O'Keefe
    Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Clin Gastroenterol Hepatol 4:6-10. 2006
    b>Short bowel syndrome (SBS)-associated intestinal failure is a highly disabling condition that impairs quality of life and social integration...
  36. ncbi 3-0 methylglucose absorption in vivo correlates with nutrient absorption and intestinal surface area in experimental short bowel syndrome
    Gary R Martin
    Gastrointestinal Research Group, University of Calgary, AB, Canada
    JPEN J Parenter Enteral Nutr 27:65-70. 2003
    ..METHODS: Using a rat model, varying degrees of short bowel syndrome (SBS) were induced: sham operation (intestinal transection only), 50% resection (R50), 75% resection (R75), ..
  37. ncbi Glucagon-like peptide-2 induces intestinal adaptation in parenterally fed rats with short bowel syndrome
    Gary R Martin
    University of Calgary, Gastrointestinal Research Group, Calgary, Alberta, Canada, T2T 5C7
    Am J Physiol Gastrointest Liver Physiol 286:G964-72. 2004
    ..we investigate the effects of GLP-2 in a total parenteral nutrition (TPN)-supported model of experimental short bowel syndrome. Juvenile Sprague-Dawley rats underwent a 90% small intestinal resection and jugular catheter insertion...
  38. ncbi [Short bowel syndrome: which remedy, which nutrition and which surgical options?]
    M Amasheh
    Medizinische Klinik I für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charite, Berlin, Germany
    Dtsch Med Wochenschr 132:1763-7. 2007
  39. ncbi Quality of life and concerns in patients with short bowel syndrome
    E Carlsson
    Department of Surgery, Sahlgrenska University Hospital, Sweden
    Clin Nutr 22:445-52. 2003
    BACKGROUND & AIMS: the life situation in patients with short bowel syndrome was described, with focus on aspects of quality of life, worries, concerns and coping. METHODS: Twenty-eight patients (19F/9 M) participated. Mean age was 54...
  40. ncbi Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndrome
    Elisabeth Mouw
    Department of Clinical Pharmacy and Outcome Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    J Pediatr Surg 43:1025-9. 2008
    Children with short bowel syndrome (SBS) requiring central venous catheters (CVCs) may experience frequent catheter-related infections (CRIs)...
  41. ncbi Neonatal short bowel syndrome: a cohort study
    Paul W Wales
    Division of General Surgery, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
    J Pediatr Surg 40:755-62. 2005
    To date, our knowledge of morbidity and mortality in neonatal short bowel syndrome (SBS) is based on individual case series...
  42. ncbi Overview of pediatric short bowel syndrome
    Debora Duro
    Division of Gastroenterology and Nutrition and Center for Advanced Intestinal Rehabilitation at Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr Gastroenterol Nutr 47:S33-6. 2008
    b>Short bowel syndrome (SBS) is a malabsorptive state occuring as a result of surgical resection or congenital disease of a significant portion of the small intestine ...
  43. ncbi Dietary and medical management of short bowel syndrome in adult patients
    Laura E Matarese
    Intestinal Rehabilitation and Transplant Center, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Clin Gastroenterol 40:S85-93. 2006
    ..Individualized and tailored nutritional management for patients with short bowel syndrome (SBS) helps to optimize intestinal absorption, leading to nutritional independence such that a patient can ..
  44. ncbi Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome
    G R Martin
    University of Calgary, Gastrointestinal Research Group, Health Sciences Bldg, Rm 1746, 3330 Hospital Dr NW, Calgary, AB, Canada T2N 4N1
    Am J Physiol Gastrointest Liver Physiol 288:G431-8. 2005
    ..These findings suggest that GLP-2 is important in initiating and maintaining the small intestinal adaptive response to resection...
  45. ncbi Low-dose growth hormone in adult home parenteral nutrition-dependent short bowel syndrome patients: a positive study
    David Seguy
    Department of Nutrition, University Hospital, Lille, France
    Gastroenterology 124:293-302. 2003
    ..01), without any major adverse effect. CONCLUSIONS: Three weeks of low-dose GH significantly improved intestinal absorption in HPN-dependent SBS patients who were on a hyperphagic western diet...
  46. ncbi Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome?
    Menghua Luo
    Department of Medicine, Emory Center for Clinical and Molecular Nutrition, Emory University School of Medicine, Atlanta, Georgia, USA
    JPEN J Parenter Enteral Nutr 31:1-7. 2007
    Sensitive biomarkers for intestinal absorptive function would be clinically useful in short bowel syndrome (SBS). Citrulline (Cit) is a product of the metabolism of glutamine (Gln) and derived amino acids by enterocytes...
  47. ncbi Body composition in patients with short bowel syndrome: an assessment by bioelectric impedance spectroscopy (BIS) and dual-energy absorptiometry (DXA)
    E Carlsson
    Department of Surgery, University of Goteborg, Sweden
    Eur J Clin Nutr 58:853-9. 2004
    To describe body composition in patients with short bowel syndrome (SBS) by using bioelectric impedance spectroscopy (BIS), dual-energy X-ray absorptiometry (DXA) measurements and anthropometrical-derived estimates.
  48. ncbi Hydrolyzed versus nonhydrolyzed protein diet in short bowel syndrome in children
    Janusz Ksiazyk
    Department of Gastroenterology, Hepatology and Nutrition, Children s Memorial Health Institute, Warsaw, Poland
    J Pediatr Gastroenterol Nutr 35:615-8. 2002
    There is no consensus regarding the optimal enteral formula in patients with neonatal short bowel syndrome. The common practice in many centers is to give a semielemental diet.
  49. ncbi Nutrition support of infants with short bowel syndrome
    Maria-Stella Serrano
    Department of Pediatrics, Louisiana Health Sciences Center, New Orleans, Louisiana 70112-2822, USA
    Nutrition 18:966-70. 2002
  50. ncbi Long-term outcome of a patient with congenital short bowel syndrome
    Paulina Ordonez
    University of Colorado Denver Health Sciences Center/The Children's Hospital, Denver, Colorado, USA
    J Pediatr Gastroenterol Nutr 42:576-80. 2006
  51. ncbi Short bowel syndrome: clinical guidelines for nutrition management
    Laura E Matarese
    Intestinal Rehabilitation and Transplant Center, Thomas E Starzl Transplantation Institute, UPMC Montefiore, 7 South, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA
    Nutr Clin Pract 20:493-502. 2005
    ..The most common cause of intestinal failure is short bowel syndrome (SBS) defined as <200 cm of functional small intestine...
  52. ncbi The effectiveness of growth hormone, glutamine and a low-fat diet containing high-carbohydrate on the enhancement of the function of remnant intestine among patients with short bowel syndrome: a review of published trials
    M Irving
    Department of Surgery, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Clin Nutr 20:199-204. 2001
    ..Such patients can be defined as having intestinal failure resulting from the short bowel syndrome. In 1995, Wilmore's group hypothesized that the administration of growth factors and nutrients could ..
  53. ncbi Short bowel syndrome in infants and children: an overview
    D L Sigalet
    The Alberta Children's Hospital, Calgary, Alberta, Canada
    Semin Pediatr Surg 10:49-55. 2001
    b>Short bowel syndrome is a spectrum of malnutrition resulting from inadequate bowel length...
  54. ncbi Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomes
    D J Andorsky
    Harvard Medical School, Boston, Massachusetts, USA
    J Pediatr 139:27-33. 2001
    OBJECTIVE: To determine correlates of clinical outcomes in patients with short bowel syndrome (SBS)...
  55. ncbi Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patients
    P B Jeppesen
    Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Gut 54:1224-31. 2005
    Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy...
  56. ncbi Enteral nutrition in short bowel syndrome
    J A Vanderhoof
    Department of Pediatrics, University of Nebraska, Omaha, Nebraska 68198-5160, USA
    Semin Pediatr Surg 10:65-71. 2001
    Enteral nutrition in pediatric short bowel syndrome is a key component in facilitating a child's growth and development...
  57. ncbi Management of the short bowel syndrome after extensive small bowel resection
    Jutta Keller
    Israelitic Hospital, Orchideenstieg 14, 22297 Hamburg, Germany
    Best Pract Res Clin Gastroenterol 18:977-92. 2004
    b>Short bowel syndrome (SBS) is a global malabsorption syndrome that results from extensive intestinal resections. It used to be a typical complication of repetitive bowel resections in patients with Crohn's disease...
  58. ncbi Serum citrulline levels correlate with enteral tolerance and bowel length in infants with short bowel syndrome
    J Marc Rhoads
    Department of Pediatrics, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
    J Pediatr 146:542-7. 2005
    To determine if serum levels of CIT (a nonprotein amino acid synthesized by the intestine) correlate with total parenteral nutrition (PN)-independence in children with short bowel syndrome (SBS).
  59. ncbi Tube feeding improves intestinal absorption in short bowel syndrome patients
    Francisca Joly
    Gastroenterology and Nutrition Support, Center for Intestinal Failure, Adult Approved Home Parenteral Nutrition Center of Paris Ile de France, Pôle des Maladies de l Appareil Digestif PMAD, AP HP, Beaujon Hospital, Clichy, France
    Gastroenterology 136:824-31. 2009
    Tube feeding, recommended for patients with short bowel syndrome in only the postoperative period, has not been compared with oral feeding for absorption...
  60. ncbi Short bowel syndrome: a nutritional and medical approach
    Khursheed N Jeejeebhoy
    St Michael's Hospital, and Department of Medicine, University of Toronto, Ont
    CMAJ 166:1297-302. 2002
  61. ncbi Growth hormone, glutamine, and an optimal diet reduces parenteral nutrition in patients with short bowel syndrome: a prospective, randomized, placebo-controlled, double-blind clinical trial
    Theresa A Byrne
    Laboratory for Surgical Metabolism and Nutrition, Department of Surgery, Brigham and Woman's Hospital, Harvard Medical School, Boston, MA, USA
    Ann Surg 242:655-61. 2005
    ..GH) and glutamine (Gln) might allow for a reduction in parenteral nutrition (PN) in individuals with short bowel syndrome. BACKGROUND DATA: Following massive intestinal resection, patients frequently sustain severe nutrient ..
  62. ncbi Liver disease associated with intestinal failure in the small bowel syndrome
    Rafael Kemp
    Division of Gastroenterology, Department of Surgery and Anatomy, FMRP, USP, Brazil
    Acta Cir Bras 21:67-71. 2006
    ..TPN) has given rise to a new hope in the treatment of intestinal failure (LF) associated with the Short Bowel Syndrome (SBS)...
  63. ncbi Outcome and long-term growth after extensive small bowel resection in the neonatal period: a survey of 87 children
    O Goulet
    Gastroenterology and Nutrition Department, Hopital des Enfants Malades, Paris, France
    Eur J Pediatr Surg 15:95-101. 2005
    ..This retrospective study aims to analyze the outcome, the prognosis factors and the long-term growth of children after extensive small bowel (SB) resection in the neonatal period...
  64. ncbi Intestinal growth in parenterally-fed rats induced by the combined effects of glucagon-like peptide 2 and epidermal growth factor
    Paul A Kitchen
    St Mark's Hospital, Imperial College London, Harrow, United Kingdom
    JPEN J Parenter Enteral Nutr 29:248-54. 2005
    ..thus have the potential to benefit patients fed parenterally, such as those with intestinal failure from short bowel syndrome. We report studies aimed to determine whether there may be synergistic effects of these 2 peptides...
  65. ncbi Serial transverse enteroplasty is associated with successful short-term outcomes in infants with short bowel syndrome
    Patrick J Javid
    Department of Surgery, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr Surg 40:1019-23; discussion 1023-4. 2005
    ..serial transverse enteroplasty (STEP) has been shown to improve nutritional indices in an animal model of short bowel syndrome. The aim of this study was to review short-term surgical and nutritional outcomes in the first cohort of ..
  66. ncbi Management of intestinal failure
    K Soondrum
    Department of Child Health, King's College Hospital, London, United Kingdom
    Indian J Pediatr 73:913-8. 2006
    ..Prolonged IF is seen after large intestinal resection and described as short bowel syndrome (SBS)...
  67. ncbi Effects of the combined use of glutamine and growth hormone in the intestinal adaptation after massive resection of the small bowel in rats
    Joaquim M Spadoni
    Department of Surgery, University of Cuiab
    Acta Cir Bras 20:382-9. 2005
    ..01). There was a significant increase in the intestinal wall width and crypt depth in the control group (p < 0.01). CONCLUSION: Gut adaptation after massive resection is improved with the combined use of glutamine and GH...
  68. ncbi Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome
    Xiaowen Liu
    Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA
    Am J Clin Nutr 84:1142-50. 2006
    BACKGROUND: Short bowel syndrome (SBS) can lead to intestinal failure and require total or supplemental parenteral nutrition (TPN or PN, respectively)...
  69. ncbi Acellular dermal matrix provides a good option for abdominal wall closure following small bowel transplantation: a case report
    E Asham
    Department of Surgery, Division of Organ Transplantation, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
    Transplant Proc 38:1770-1. 2006
    ..This is the first report of the use of ADM for abdominal closure in patients receiving a SBTx. ADM is considered safe when used in contaminated sites and can allow primary closure of difficult wounds often seen in SBTx patients...
  70. ncbi [Extensive small bowel resections]
    Filippo Ferrarese
    UO Chirurgia Generale IV, Dipartimento di Scienze Chirurgiche Generali e Specialistiche,
    Chir Ital 57:631-4. 2005
    ..In more extensive resections, involving a longer adaptation time, enteral nutrition was supplemented with total parenteral nutrition for lengthier periods...
  71. ncbi Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets
    Anne L Bartholome
    Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    JPEN J Parenter Enteral Nutr 28:210-22; discussion 222-3. 2004
    ..Ultimately, butyrate administration may enable an infant with short-bowel syndrome to successfully transition to enteral feedings by maximizing their absorptive area...
  72. ncbi Intestinal adaptation after massive intestinal resection
    A R Weale
    Department of Surgery, Southmead Hospital, North Bristol NHS Hospitals Trust, Westbury on Trym, Bristol BS10 5NB, UK
    Postgrad Med J 81:178-84. 2005
    Patients with short bowel syndrome require long term parenteral nutrition support. However, after massive intestinal resection the intestine undergoes adaptation and nutritional autonomy may be obtained...
  73. ncbi Surgical therapy for short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, 555 University Avenue, Rm 1526, Toronto, Ontario M5G 1X8, Canada
    Pediatr Surg Int 20:647-57. 2004
    Patients with short bowel syndrome (SBS) suffer tremendous morbidity secondary to prolonged hospitalization and chronic parenteral nutrition (TPN)...
  74. ncbi The nutritional management of short bowel syndrome
    Christian S Jackson
    Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
    Nutr Clin Care 7:114-21. 2004
    b>Short bowel syndrome (SBS) is the predominant cause of intestinal failure and is associated with a high degree of morbidity and mortality. One of the reasons this occurs is because of the dramatic reduction in nutrient absorptive capacity...
  75. ncbi [Clinical results of intestinal and multivisceral transplantation at the Charité, Berlin. A case series]
    A Pascher
    Klinik fUr Allgemein, Viszeral und Transplantationschirurgie
    Dtsch Med Wochenschr 130:387-92. 2005
    Intestinal transplantation (ITx) is the only causal therapy of short bowel syndrome (SBS). Long-term survival after ITx has been improved significantly during the last years...
  76. ncbi Irreversible intestinal failure
    Olivier Goulet
    Département de gastroentérologie, Hépatologie et Nutrition Pédiatriques, Hôpital Necker Infants Malades and INSERM, Faculté de Necker, Paris, France
    J Pediatr Gastroenterol Nutr 38:250-69. 2004
    ..b>Short bowel syndrome was the first commonly recognized cause of protracted IF...
  77. ncbi Gut hormones, and short bowel syndrome: the enigmatic role of glucagon-like peptide-2 in the regulation of intestinal adaptation
    G R Martin
    Department of Gastrointestinal Sciences, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
    World J Gastroenterol 12:4117-29. 2006
    b>Short bowel syndrome (SBS) refers to the malabsorption of nutrients, water, and essential vitamins as a result of disease or surgical removal of parts of the small intestine...
  78. ncbi Superior mesenteric vein thrombosis after colectomy in a patient with Crohn's disease
    Andrew S Ross
    Department of Surgery, University of Chicago, IL, USA
    Nat Clin Pract Gastroenterol Hepatol 2:281-5; quiz 1 p following 285. 2005
    ..DIAGNOSIS: Acute mesenteric ischemia secondary to superior mesenteric vein thrombosis. MANAGEMENT: Resection of necrotic bowel, antibiotics and systemic anticoagulation...
  79. ncbi Total parenteral nutrition, intestinal adaptation, and short bowel syndrome
    Herbert R Freund
    Department of Surgery, Hadassah University Hospital Mount Scopus and Hebrew University, Hadassah Medical School, Jerusalem, Israel
    Nutrition 20:337. 2004
  80. ncbi Late regeneration of infarcted small bowel mucosa: a case report
    Oded Zmora
    Department of Surgery and Transplantation, Sheba Medical Center, Sackler School of Medicine, Tel Aviv, Israel
    JPEN J Parenter Enteral Nutr 29:131-3. 2005
    ..Sixteen months after the injury, normal mucosa covered the entire small bowel, and enteral feeding resumed successfully. This report shows that infarcted small-bowel mucosa may regenerate even months after injury...
  81. ncbi Glucagon-like peptide-2 induces a specific pattern of adaptation in remnant jejunum
    D L Sigalet
    University of Calgary, Gastrointestinal Research Group, Calgary, Alberta, Canada
    Dig Dis Sci 51:1557-66. 2006
    ..Herein we investigate the effects of GLP-2 on the jejunal remant using a rat model of short bowel syndrome (SBS)...
  82. ncbi [Massive intestinal resection: Nutricional adaptation process]
    J M Moreno Villares
    Nutr Hosp 23:171-2; author reply 172. 2008
  83. ncbi Long-term outcome, growth and digestive function in children 2 to 18 years after intestinal transplantation
    F Lacaille
    Pediatric Gastroenterology Hepatology Nutrition Unit, Necker Enfants Malades Hospital, 149 rue de Sevres, 75015 Paris, France
    Gut 57:455-61. 2008
    ..In this retrospective study, we analysed graft functions in 31 children after SBTx with a follow-up of 2-18 years (median 7 years)...
  84. ncbi New dietary concepts in small bowel transplantation
    R-J Schulz
    Hepatology, Gastroenterology, Charit, Campus Virchow Klinikum, , 13353, Berlin, Germany
    Transplant Proc 34:893-5. 2002
  85. ncbi Role of extrinsic innervation in jejunal absorptive adaptation to subtotal small bowel resection: a model of segmental small bowel transplantation
    Karen D Libsch
    Gastroenterology Research Unit and Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
    J Gastrointest Surg 6:240-7. 2002
    ..The extrinsic denervation necessitated by small bowel transplantation does not appear to blunt the net jejunal adaptive response to total ileal resection, but may temporarily alter glutamine absorption...
  86. ncbi Distribution of the H+/peptide transporter PepT1 in human intestine: up-regulated expression in the colonic mucosa of patients with short-bowel syndrome
    Thomas R Ziegler
    Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Am J Clin Nutr 75:922-30. 2002
    ..Intestinal adaptation after massive bowel resection in animal models is characterized by increased gut-mucosal growth and expression of nutrient transporters. Few data about these indexes exist in humans with short-bowel syndrome (SBS)...
  87. ncbi Impairment of arginine metabolism in rats after massive intestinal resection: effect of parenteral nutrition supplemented with citrulline compared with arginine
    Sylwia Osowska
    Laboratoire de Biologie de la Nutrition, EA 2498, Faculté de Pharmacie Université Paris Descartes, 4 avenue de l Observatoire, 75270 Paris Cedex 06, France
    Clin Sci (Lond) 115:159-66. 2008
    Arginine homoeostasis is impaired in short bowel syndrome, but its supplementation in short bowel syndrome patients remains controversial...
  88. ncbi Does ileal reverse segment in rats with short bowel syndrome change intestinal morphology?
    Aydin Sencan
    Department of Pediatric Surgery, Faculty of Medicine of Celal Bayar University, Manisa, Turkey
    J Pediatr Gastroenterol Nutr 34:165-8. 2002
    The primary goal of surgical therapy for short bowel syndrome is to increase intestinal absorptive capacity. Many surgical procedures have been described for this purpose. One of these is ileal reverse-segment procedure...
  89. ncbi Clinical outcome in patients from a single region who were dependent on parenteral nutrition for 28 days or more
    J Koglmeier
    Department of Paediatric Gastroenterology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH
    Arch Dis Child 93:300-2. 2008
    ..The ideal model for service provision is a subject of debate...
  90. ncbi The management of patients with the short bowel syndrome
    Cameron F E Platell
    Department of Surgery, The University of Western Australia, Perth, Australia
    World J Gastroenterol 8:13-20. 2002
    The surgeon is invariably the primary specialist involved in managing patients with short bowel syndrome. Because of this they will play an important role in co-ordinating the management of these patients...
  91. ncbi Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experiment
    X Zhou
    Research Institute of General Surgery, Chinese PLA General Hospital of Nanjing Military Area, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China
    World J Gastroenterol 7:66-73. 2001
    ..Enteral glutamine perfusion is beneficial in preserving small bowel mucosal structure during TPN, but has little beneficial effect during EN...
  92. ncbi Effect of IGF-rich colostrum on bowel adaptation in neonatal piglets with short bowel syndrome
    V H Heemskerk
    Department of Surgery, the University of Maastricht, Maastricht, The Netherlands
    J Pediatr Gastroenterol Nutr 34:47-51. 2002
    ..this study was that colostrum rich in IGF-1 could promote small bowel adaptation in neonatal piglets with short bowel syndrome. METHODS: Twenty-four piglets, aged 7 days, underwent 75% small bowel resection and were fed 525 kJ x kg(-1)..
  93. ncbi Intestinal function and metabolism in the early adaptive phase after massive small bowel resection in the rat
    C F Welters
    Department of Surgery, University Hospital Maastricht, Maastricht University, Maastricht, The Netherlands
    J Pediatr Surg 36:1746-51. 2001
    ..This, however, is accompanied by an increase in intestinal permeability, which may indicate impaired intestinal barrier function. J Pediatr Surg 36:1746-1751...
  94. ncbi Long-term cognitive functions in neonatal short bowel syndrome patients
    J Huang
    Clinical Nutrition Center, Shanghai Jiao Tong University, School of Medicine, Xin Hua Hospital, Shanghai, China
    Eur J Pediatr Surg 18:89-92. 2008
    The aim of the study was to evaluate the long-term effects of neonatal short bowel syndrome on cognitive functions during development.
  95. ncbi Fasting plasma citrulline concentrations do not reflect intestinal absorption capacity
    Job H C Peters
    JPEN J Parenter Enteral Nutr 32:288; author reply 289. 2008
  96. ncbi Novel effect of leptin on small intestine adaptation
    P Y Pearson
    Department of Surgery, A.I. duPont Hospital for Children, Wilmington, Delaware 19899, USA
    J Surg Res 97:192-5. 2001
    ..Leptin may be clinically useful in patients with inadequate intestinal function...
  97. ncbi Pediatric intestinal failure: nutrition, pharmacologic, and surgical approaches
    Y Avery Ching
    Children s Hospital of Boston, Department of Surgery, Fegan 3, 300 Longwood Avenue, Boston, MA 02115, USA
    Nutr Clin Pract 22:653-63. 2007
    ..IF is a difficult disease process with a complex patient population and is best guided through this 3-pronged approach by a multidisciplinary team featuring surgeons, gastroenterologists, dietitians, pharmacists, and nurses...
  98. ncbi Short bowel syndrome
    James S Scolapio
    JPEN J Parenter Enteral Nutr 26:S11-6. 2002
  99. ncbi Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndrome
    Paul W Wales
    Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
    J Pediatr Surg 42:1804-10. 2007
    ..The aim of this study was to report intermediate outcomes in patients who have received the STEP at our institution using clinical and biochemical assessment of intestinal function...
  100. ncbi New and emerging therapies for short bowel syndrome in children
    Jon A Vanderhoof
    Department of Pediatric Gastroenterology and Nutrition, University of Nebraska Medical Center, Omaha, Nebraska 68198 5160, USA
    Paediatr Drugs 5:525-31. 2003
    ..provides an overview of traditional as well as emerging therapies useful in the management of pediatric short bowel syndrome. Pediatric short bowel syndrome is relatively uncommon; however, when it does occur, it presents a unique ..
  101. ncbi Promoting intestinal adaptation
    Katharina Wallis
    Lennard Jones Intestinal Failure Unit, St Mark's Hospital, Harrow
    Br J Hosp Med (Lond) 68:11-4. 2007

Research Grants82

  1. AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTION
    HARRY SAX; Fiscal Year: 2004
    b>Short bowel syndrome is a devastating clinical condition which leads to dehydration, muscle wasting, debilitation and death...
  2. NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATION
    Marc Levin; Fiscal Year: 2009
    DESCRIPTION (provided by investigator): Short bowel syndrome resulting from diminished intestinal absorptive function is a major cause of morbidity and impaired quality of life...
  3. Short-Chain Fatty Acid Enhanced Intestinal Adaptation
    KELLY TAPPENDEN; Fiscal Year: 2006
    ..abstract_text> ..
  4. Mechanisms of Intestinal Stem Cell Expansion Following Resection
    Michael A Helmrath; Fiscal Year: 2009
    ..The increased incidence of chronic short bowel syndrome (SBS) in these patients suggests that TPN-feeding may attenuate the normal adaptive ISC expansion...
  5. Mechanisms of Intestinal Stem Cell Expansion Following Resection
    Michael A Helmrath; Fiscal Year: 2010
    ..The increased incidence of chronic short bowel syndrome (SBS) in these patients suggests that TPN-feeding may attenuate the normal adaptive ISC expansion...
  6. TOTAL PARENTERAL NUTRITION AND INTESTINAL ADAPTION
    Denise Ney; Fiscal Year: 2006
    b>Short bowel syndrome often requires permanent total parenteral nutrition. Current treatment is inadequate because TPN induces serious complications and is expensive...
  7. Novel Polymers for Tissue Engineering
    ROBERT SAMUEL LANGER; Fiscal Year: 2010
    b>Short Bowel Syndrome (SBS) is a devastating clinical disorder that has a high prevalence of mortality and morbidity and takes a severe socioeconomic toll on patients...
  8. NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATION
    Marc Levin; Fiscal Year: 2007
    b>Short bowel syndrome resulting from diminished intestinal absorptive function is a major cause of morbidity and impaired quality of life...
  9. Enterocyte Apoptosis after Intestinal Resection
    Brad Warner; Fiscal Year: 2006
    ..The long-term goal of this project is to optimize therapy for patients with the short bowel syndrome by delineating the significance of enterocyte apoptosis during intestinal adaptation...
  10. Parenteral Nutrition: Intestinal Metabolism/Adaptation
    Denise Ney; Fiscal Year: 2009
    b>Short bowel syndrome (SBS) often requires parenteral nutrition (PN)...
  11. Physiological role of GLP-2 receptor in the mouse intestinal growth and function
    Xinfu Guan; Fiscal Year: 2007
    ..g. short bowel syndrome), which may facilitate to develop new drugs to treat intestinal disease/ dysfunction...
  12. CELL CYCLE REGULATION IN INTESTINAL REGENERATION
    Edward Whang; Fiscal Year: 2004
    ..The long-term goal of this proposal is to develop new strategies for treating patients suffering from the short bowel syndrome. Chronic total parenteral nutrition and intestinal transplantation are currently the only available options ..
  13. Enterogenesis with the Use of an Implanted Mechanotransduction Device
    Daniel Teitelbaum; Fiscal Year: 2007
    b>Short bowel syndrome (SBS) is a devastating surgical disease with a high morbidity and mortality. SBS results in a series of adaptive processes, including proliferation, apoptosis, and increased absorptive capacity...
  14. Stem cell-based renewal and regeneration in the intestine of a model organism
    DAVID FORSTHOEFEL; Fiscal Year: 2006
    ..g. short bowel syndrome) would be clinically beneficial...