Genomes and Genes
short bowel syndrome
Summary: A malabsorption syndrome resulting from extensive operative resection of the SMALL INTESTINE, the absorptive region of the GASTROINTESTINAL TRACT.
Publications226 found, 100 shown here
- Guidelines for management of patients with a short bowelJ Nightingale
St Mark's Hospital, Harrow HA1 3UJ, UK
Gut 55:iv1-12. 2006
- Long-term survival and parenteral nutrition dependence in adult patients with the short bowel syndromeB Messing
Department of Hepatogastroenterology, INSERM Unité 290, Hôpital Lariboisière Saint Lazare, Paris, France
Gastroenterology 117:1043-50. 1999The short bowel syndrome (SBS) may be associated with either transient or permanent intestinal failure, presently treated by parenteral nutrition (PN)...
- Advances in the management of short bowel syndromeChristian Jackson
Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Curr Gastroenterol Rep 7:373-8. 2005b>Short bowel syndrome (SBS) is the predominant cause of intestinal failure and is thus associated with a high degree of morbidity and mortality. One of the reasons this occurs is the dramatic reduction in nutrient absorptive capacity...
- Small bowel bacterial overgrowth: a negative factor in gut adaptation in pediatric SBSConrad R Cole
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, 2015 Uppergate Drive, Atlanta, GA 30322, USA
Curr Gastroenterol Rep 9:456-62. 2007Small bowel bacterial overgrowth (SBBO) is common in infants and children with short bowel syndrome (SBS). Its occurrence is due to alterations in anatomy, motility, and secretion, which promote the abnormal growth of bacteria...
- Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colonP B Jeppesen
Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, Denmark
Gut 47:370-6. 2000..Ileum resected short bowel patients with a preserved colon show evidence of functional adaptation and have normal gastric emptying...
- Synovial lipomatosis (lipoma arborescens) affecting multiple joints in a patient with congenital short bowel syndromeChokkalingam Siva
Division of Rheumatology, Washington University School of Medicine, St. Louis, Missouri 63110, USA
J Rheumatol 29:1088-92. 2002..The co-occurrence with congenital short bowel syndrome may have etiological implications for this disorder of inappropriate fat deposition.
- Etiology and initial management of short bowel syndromeAlan L Buchman
Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Gastroenterology 130:S5-S15. 2006
- Randomised placebo-controlled trial of teduglutide in reducing parenteral nutrition and/or intravenous fluid requirements in patients with short bowel syndromeP B Jeppesen
Department of Gastroenterology CA 2121, Rigshospitalet, Copenhagen, Denmark
Gut 60:902-14. 2011..reducing gastric emptying and secretion, thereby increasing fluid and nutrient absorption in patients with short bowel syndrome (SBS)...
- Some new insights in intestinal failure-associated liver diseaseOlivier Goulet
Department of Pediatric Gastroenterology, Hepatology and Nutrition, Intestinal Failure Rehabilitation Center, Hospital Necker Enfants Malades, University of Paris Descartes, 75743 Paris Cedex 15, Paris, France
Curr Opin Organ Transplant 14:256-61. 2009..To point new insights in the cholestasis that is a complication of both intestinal failure and parenteral nutrition. View on liver disease has recently evolved with the onset of fish oil-based intravenous lipid emulsions (ILE)...
- Morphological adaptation with preserved proliferation/transporter content in the colon of patients with short bowel syndromeFrancisca Joly
Service de Gastroentérologie et Assistance Nutritive, Pôle des Maladies de l Appareil Digestif, Hopital Beaujon, Clichy, France
Am J Physiol Gastrointest Liver Physiol 297:G116-23. 2009In short bowel syndrome (SBS), although a remaining colon improves patient outcome, there is no direct evidence of a mucosal colonic adaptation in humans...
- Intestinal rehabilitation and the short bowel syndrome: part 2John K DiBaise
Department of Internal Medicine, University of Nebraska Medical Center, 982000 Nebraska Medical Center, Omaha, NE 68198-2000, USA
Am J Gastroenterol 99:1823-32. 2004The management of patients with intestinal failure due to short bowel syndrome is complex, requiring a comprehensive approach that frequently necessitates long-term, if not life-long, use of parenteral nutrition...
- The effect of growth hormone supplementation on late nutritional independence in pediatric patients with short bowel syndromeAlan P Ladd
Section of Pediatric Surgery, Department of Surgery, Indiana University School of Medicine and Riley Children s Hospital, Indianapolis, IN 46202, USA
J Pediatr Surg 40:442-5. 2005The use of growth hormone (GH) supplementation for intestinal adaptation among adult patients with short bowel syndrome (SBS) has provided mixed results. This report examines the effect of GH supplementation on SBS in pediatric patients.
- Teduglutide for the treatment of short bowel syndromeMarcus Ferrone
Department of Pharmacy Nutrition Mayo Clinic St Luke s Hospital, Jacksonville, FL 32216, USA
Ann Pharmacother 40:1105-9. 2006To summarize the pharmacology, development, and clinical application of teduglutide (ALX-0600), a glucagon-like peptide-2 (GLP-2) analog for the treatment of short bowel syndrome (SBS).
- Gastrocolocutaneous fistula in a child with congenital short bowel syndrome: a rare complication of percutaneous endoscopic gastrostomyYun Chen
Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
J Formos Med Assoc 103:306-10. 2004..We report a case of this complication in a 2-year-old boy with congenital short bowel syndrome with dilated bowel loops who underwent PEG insertion...
- Effect of recombinant human growth hormone and enteral nutrition on short bowel syndromeZhu Weiming
From the Department of General Surgery, Jinling Hospital, Nanjing, Jiangsu, China
JPEN J Parenter Enteral Nutr 28:377-81. 2004..rhGH), nutrition support, glutamine, and dietary fiber, promotes intestinal adaptation in patients with short bowel syndrome. The aim of the current study was to determine if enteral nutrition and rhGH are effective in weaning short ..
- Glucagon-like peptide-2: update of the recent clinical trialsPalle Bekker Jeppesen
Department of Medicine, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark
Gastroenterology 130:S127-31. 2006..In this respect, glucagon-like peptide 2 (GLP-2) has received attention. In this review, the nature of the short bowel syndrome is described, and the antisecretory, transit-modulating, but also intestinotrophic effects of GLP-2 are ..
- Rehabilitation therapy for short bowel syndromeWeiming Zhu
Department of General Surgery, Jinling Hospital, Clinical School of Nanjing University, Nanjing 210002, China
Chin Med J (Engl) 115:776-8. 2002To investigate the effect of rehabilitation therapy for short bowel syndrome on patient nutritional status and intestinal adaptation.
- Intestinal permeability and effects of Lactobacillus rhamnosus therapy in children with short bowel syndromeTimothy A Sentongo
Division of Gastroenterology, Hepatology and Nutrition, University of Chicago, Comer Children s Hospital, Chicago, IL 60637, USA
J Pediatr Gastroenterol Nutr 46:41-7. 2008The present study was conducted to investigate the effects of Lactobacillus rhamnosus (also known as LGG) on intestinal permeability (IP) in children with short bowel syndrome (SBS).
- Serial transverse enteroplasty (STEP): a novel bowel lengthening procedureHeung Bae Kim
Department of Surgery, Children's Hospital and Harvard Medical School, and Harvard Center for Minimally Invasive Surgery, Boston, Massachusetts 02115, USA
J Pediatr Surg 38:425-9. 2003BACKGROUND/PURPOSE: Bowel lengthening may be beneficial for children with short bowel syndrome. However, current techniques require at least one intestinal anastomosis and place the mesenteric blood supply at risk...
- Mesenteric thrombosis causing short bowel syndrome in nephrotic syndromeTim Ulinski
Department of Pediatric Nephrology, , 26 avenue du Dr. Arnold-Netter, 75571 Paris Cedex 12, France
Pediatr Nephrol 18:1295-7. 2003..Oral cyclosporin A (CyA) was initiated for long-term treatment. Due to a short bowel syndrome with severe malabsorption, even oral administration of 22...
- Surgical approaches to improving intestinal function in the short-bowel syndromeJ S Thompson
Department of Surgery, University of Nebraska Medical Center, Omaha Veterans Affairs Medical Center, USA
Arch Surg 134:706-9; discussion 709-11. 1999..Nontransplantation surgical approaches to improve intestinal function in patients with the short-bowel syndrome have a satisfactory outcome in selected patients...
- Postoperative short bowel syndromeJon S Thompson
Department of Surgery, University of Nebraska Medical Center, Omaha, NE 68198-3280, USA
J Am Coll Surg 201:85-9. 2005BACKGROUND: Unanticipated massive resection after intraabdominal procedures is an increasing cause of short bowel syndrome (SBS). Our aim was to determine the frequency and potential mechanisms of postoperative SBS...
- Clinical significance of GLP-2 in short-bowel syndromeP B Jeppesen
Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University of Copenhagen, DK 2100 Copenhagen, Denmark
J Nutr 133:3721-4. 2003....
- Comparison of massive vs. repeated resection leading to short bowel syndromeJ S Thompson
Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198 3280, USA
J Gastrointest Surg 4:101-4. 2000b>Short bowel syndrome can result from either a single massive intestinal resection or repeated lesser resections, which might have prognostic implications...
- AGA technical review on short bowel syndrome and intestinal transplantationAlan L Buchman
Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
Gastroenterology 124:1111-34. 2003
- Short bowel syndrome: epidemiology and etiologyPaul W Wales
Group for Improvement of Intestinal Function and Treatment GIFT, Hospital for Sick Children, Toronto, Ontario, Canada
Semin Pediatr Surg 19:3-9. 2010Pediatric short bowel syndrome (SBS) is most commonly caused by congenital or acquired conditions of the newborn...
- Citrulline blood levels as indicators of residual intestinal absorption in patients with short bowel syndromeLidia Santarpia
Dipartimento di Medicina Clinica e Sperimentale, Universita di Napoli Federico II, Napoli, Italy
Ann Nutr Metab 53:137-42. 2008..We studied 25 patients with short bowel syndrome (SBS) after at least 18 months since last digestive circuit modification; 24 of them were again evaluated 1 ..
- Multiple micronutrient deficiencies in a child with short bowel syndrome and normal somatic growthDebora Duro
Division of Gastroenterology and Nutrition, Children's Hospital Boston, MA 02115, USA
J Pediatr Gastroenterol Nutr 46:461-4. 2008
- Intestinal rehabilitation and the short bowel syndrome: part 1John K DiBaise
Department of Internal Medicine, University of Nebraska Medical Center, Omaha, Nebraska 68198-2000, USA
Am J Gastroenterol 99:1386-95. 2004The management of patients with intestinal failure due to short bowel syndrome (SBS) is complex, requiring a comprehensive approach that frequently necessitates long-term, if not life-long, use of parenteral nutrition (PN)...
- Congenital short bowel syndrome: a case report and review of the literatureMohammed Hasosah
University of British Columbia, Vancouver, Canada
Can J Gastroenterol 22:71-4. 2008Congenital short bowel syndrome (SBS) is a rare condition of the newborn, with several reports demonstrating high mortality. A six-week-old boy presented with chronic diarrhea and failure to thrive...
- Glucagon-like peptide 2 improves nutrient absorption and nutritional status in short-bowel patients with no colonP B Jeppesen
Department of Medicine, Section of Gastroenterology, Rigshospitalet, University Hospital of Copenhagen, Denmark
Gastroenterology 120:806-15. 2001..5 kg/day) and energy (>2.3 MJ/day) and no postprandial secretion of GLP-2...
- Immunonutritional effects during synbiotics therapy in pediatric patients with short bowel syndromeKeiichi Uchida
Department of Gastrointestinal and Pediatric Surgery, Mie University Graduate School of Medicine, Edobashi 2 174, Tsu, Mie, 514 0064, Japan
Pediatr Surg Int 23:243-8. 2007The aim of this study was to evaluate the effects of synbiotic therapy in patients with short bowel syndrome (SBS)...
- Plasma ghrelin levels in patients with short bowel syndromeMichal Krsek
3rd Department of Internal Medicine, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Endocr Res 28:27-33. 2002..This study was aimed to investigate the changes in plasma ghrelin levels in patients with short bowel syndrome. Twenty-four patients with malnutrition due to short bowel syndrome and eleven healthy controls were ..
- Short bowel syndrome following bariatric surgical proceduresCorrigan L McBride
Department of Surgery, University of Nebraska Medical Center, 983280 Nebraska Medical Center, Omaha, NE 68198 3280, USA
Am J Surg 192:828-32. 2006b>Short bowel syndrome (SBS) is a potential postoperative complication that is occurring with increasing frequency after bariatric procedures (BP)...
- Short bowel syndrome and intestinal failure: consensus definitions and overviewStephen J D O'Keefe
Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
Clin Gastroenterol Hepatol 4:6-10. 2006b>Short bowel syndrome (SBS)-associated intestinal failure is a highly disabling condition that impairs quality of life and social integration...
- 3-0 methylglucose absorption in vivo correlates with nutrient absorption and intestinal surface area in experimental short bowel syndromeGary R Martin
Gastrointestinal Research Group, University of Calgary, AB, Canada
JPEN J Parenter Enteral Nutr 27:65-70. 2003..METHODS: Using a rat model, varying degrees of short bowel syndrome (SBS) were induced: sham operation (intestinal transection only), 50% resection (R50), 75% resection (R75), ..
- Glucagon-like peptide-2 induces intestinal adaptation in parenterally fed rats with short bowel syndromeGary R Martin
University of Calgary, Gastrointestinal Research Group, Calgary, Alberta, Canada, T2T 5C7
Am J Physiol Gastrointest Liver Physiol 286:G964-72. 2004..we investigate the effects of GLP-2 in a total parenteral nutrition (TPN)-supported model of experimental short bowel syndrome. Juvenile Sprague-Dawley rats underwent a 90% small intestinal resection and jugular catheter insertion...
- [Short bowel syndrome: which remedy, which nutrition and which surgical options?]M Amasheh
Medizinische Klinik I für Gastroenterologie, Infektiologie und Rheumatologie, Campus Benjamin Franklin, Charite, Berlin, Germany
Dtsch Med Wochenschr 132:1763-7. 2007
- Quality of life and concerns in patients with short bowel syndromeE Carlsson
Department of Surgery, Sahlgrenska University Hospital, Sweden
Clin Nutr 22:445-52. 2003BACKGROUND & AIMS: the life situation in patients with short bowel syndrome was described, with focus on aspects of quality of life, worries, concerns and coping. METHODS: Twenty-eight patients (19F/9 M) participated. Mean age was 54...
- Use of an ethanol lock to prevent catheter-related infections in children with short bowel syndromeElisabeth Mouw
Department of Clinical Pharmacy and Outcome Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
J Pediatr Surg 43:1025-9. 2008Children with short bowel syndrome (SBS) requiring central venous catheters (CVCs) may experience frequent catheter-related infections (CRIs)...
- Neonatal short bowel syndrome: a cohort studyPaul W Wales
Division of General Surgery, The Research Institute, The Hospital for Sick Children, Toronto, Ontario, Canada M5G 1X8
J Pediatr Surg 40:755-62. 2005To date, our knowledge of morbidity and mortality in neonatal short bowel syndrome (SBS) is based on individual case series...
- Overview of pediatric short bowel syndromeDebora Duro
Division of Gastroenterology and Nutrition and Center for Advanced Intestinal Rehabilitation at Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
J Pediatr Gastroenterol Nutr 47:S33-6. 2008b>Short bowel syndrome (SBS) is a malabsorptive state occuring as a result of surgical resection or congenital disease of a significant portion of the small intestine ...
- Dietary and medical management of short bowel syndrome in adult patientsLaura E Matarese
Intestinal Rehabilitation and Transplant Center, Thomas E Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Clin Gastroenterol 40:S85-93. 2006..Individualized and tailored nutritional management for patients with short bowel syndrome (SBS) helps to optimize intestinal absorption, leading to nutritional independence such that a patient can ..
- Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndromeG R Martin
University of Calgary, Gastrointestinal Research Group, Health Sciences Bldg, Rm 1746, 3330 Hospital Dr NW, Calgary, AB, Canada T2N 4N1
Am J Physiol Gastrointest Liver Physiol 288:G431-8. 2005..These findings suggest that GLP-2 is important in initiating and maintaining the small intestinal adaptive response to resection...
- Low-dose growth hormone in adult home parenteral nutrition-dependent short bowel syndrome patients: a positive studyDavid Seguy
Department of Nutrition, University Hospital, Lille, France
Gastroenterology 124:293-302. 2003..01), without any major adverse effect. CONCLUSIONS: Three weeks of low-dose GH significantly improved intestinal absorption in HPN-dependent SBS patients who were on a hyperphagic western diet...
- Are plasma citrulline and glutamine biomarkers of intestinal absorptive function in patients with short bowel syndrome?Menghua Luo
Department of Medicine, Emory Center for Clinical and Molecular Nutrition, Emory University School of Medicine, Atlanta, Georgia, USA
JPEN J Parenter Enteral Nutr 31:1-7. 2007Sensitive biomarkers for intestinal absorptive function would be clinically useful in short bowel syndrome (SBS). Citrulline (Cit) is a product of the metabolism of glutamine (Gln) and derived amino acids by enterocytes...
- Body composition in patients with short bowel syndrome: an assessment by bioelectric impedance spectroscopy (BIS) and dual-energy absorptiometry (DXA)E Carlsson
Department of Surgery, University of Goteborg, Sweden
Eur J Clin Nutr 58:853-9. 2004To describe body composition in patients with short bowel syndrome (SBS) by using bioelectric impedance spectroscopy (BIS), dual-energy X-ray absorptiometry (DXA) measurements and anthropometrical-derived estimates.
- Hydrolyzed versus nonhydrolyzed protein diet in short bowel syndrome in childrenJanusz Ksiazyk
Department of Gastroenterology, Hepatology and Nutrition, Children s Memorial Health Institute, Warsaw, Poland
J Pediatr Gastroenterol Nutr 35:615-8. 2002There is no consensus regarding the optimal enteral formula in patients with neonatal short bowel syndrome. The common practice in many centers is to give a semielemental diet.
- Nutrition support of infants with short bowel syndromeMaria-Stella Serrano
Department of Pediatrics, Louisiana Health Sciences Center, New Orleans, Louisiana 70112-2822, USA
Nutrition 18:966-70. 2002
- Long-term outcome of a patient with congenital short bowel syndromePaulina Ordonez
University of Colorado Denver Health Sciences Center/The Children's Hospital, Denver, Colorado, USA
J Pediatr Gastroenterol Nutr 42:576-80. 2006
- Short bowel syndrome: clinical guidelines for nutrition managementLaura E Matarese
Intestinal Rehabilitation and Transplant Center, Thomas E Starzl Transplantation Institute, UPMC Montefiore, 7 South, 3459 Fifth Avenue, Pittsburgh, PA 15213, USA
Nutr Clin Pract 20:493-502. 2005..The most common cause of intestinal failure is short bowel syndrome (SBS) defined as <200 cm of functional small intestine...
- The effectiveness of growth hormone, glutamine and a low-fat diet containing high-carbohydrate on the enhancement of the function of remnant intestine among patients with short bowel syndrome: a review of published trialsM Irving
Department of Surgery, Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
Clin Nutr 20:199-204. 2001..Such patients can be defined as having intestinal failure resulting from the short bowel syndrome. In 1995, Wilmore's group hypothesized that the administration of growth factors and nutrients could ..
- Short bowel syndrome in infants and children: an overviewD L Sigalet
The Alberta Children's Hospital, Calgary, Alberta, Canada
Semin Pediatr Surg 10:49-55. 2001b>Short bowel syndrome is a spectrum of malnutrition resulting from inadequate bowel length...
- Nutritional and other postoperative management of neonates with short bowel syndrome correlates with clinical outcomesD J Andorsky
Harvard Medical School, Boston, Massachusetts, USA
J Pediatr 139:27-33. 2001OBJECTIVE: To determine correlates of clinical outcomes in patients with short bowel syndrome (SBS)...
- Teduglutide (ALX-0600), a dipeptidyl peptidase IV resistant glucagon-like peptide 2 analogue, improves intestinal function in short bowel syndrome patientsP B Jeppesen
Department of Medicine CA 2121, Section of Gastroenterology, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
Gut 54:1224-31. 2005Glucagon-like peptide 2 (GLP-2) may improve intestinal absorption in short bowel syndrome (SBS) patients with an end jejunostomy...
- Enteral nutrition in short bowel syndromeJ A Vanderhoof
Department of Pediatrics, University of Nebraska, Omaha, Nebraska 68198-5160, USA
Semin Pediatr Surg 10:65-71. 2001Enteral nutrition in pediatric short bowel syndrome is a key component in facilitating a child's growth and development...
- Management of the short bowel syndrome after extensive small bowel resectionJutta Keller
Israelitic Hospital, Orchideenstieg 14, 22297 Hamburg, Germany
Best Pract Res Clin Gastroenterol 18:977-92. 2004b>Short bowel syndrome (SBS) is a global malabsorption syndrome that results from extensive intestinal resections. It used to be a typical complication of repetitive bowel resections in patients with Crohn's disease...
- Serum citrulline levels correlate with enteral tolerance and bowel length in infants with short bowel syndromeJ Marc Rhoads
Department of Pediatrics, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
J Pediatr 146:542-7. 2005To determine if serum levels of CIT (a nonprotein amino acid synthesized by the intestine) correlate with total parenteral nutrition (PN)-independence in children with short bowel syndrome (SBS).
- Tube feeding improves intestinal absorption in short bowel syndrome patientsFrancisca Joly
Gastroenterology and Nutrition Support, Center for Intestinal Failure, Adult Approved Home Parenteral Nutrition Center of Paris Ile de France, Pôle des Maladies de l Appareil Digestif PMAD, AP HP, Beaujon Hospital, Clichy, France
Gastroenterology 136:824-31. 2009Tube feeding, recommended for patients with short bowel syndrome in only the postoperative period, has not been compared with oral feeding for absorption...
- Short bowel syndrome: a nutritional and medical approachKhursheed N Jeejeebhoy
St Michael's Hospital, and Department of Medicine, University of Toronto, Ont
CMAJ 166:1297-302. 2002
- Growth hormone, glutamine, and an optimal diet reduces parenteral nutrition in patients with short bowel syndrome: a prospective, randomized, placebo-controlled, double-blind clinical trialTheresa A Byrne
Laboratory for Surgical Metabolism and Nutrition, Department of Surgery, Brigham and Woman's Hospital, Harvard Medical School, Boston, MA, USA
Ann Surg 242:655-61. 2005..GH) and glutamine (Gln) might allow for a reduction in parenteral nutrition (PN) in individuals with short bowel syndrome. BACKGROUND DATA: Following massive intestinal resection, patients frequently sustain severe nutrient ..
- Liver disease associated with intestinal failure in the small bowel syndromeRafael Kemp
Division of Gastroenterology, Department of Surgery and Anatomy, FMRP, USP, Brazil
Acta Cir Bras 21:67-71. 2006..TPN) has given rise to a new hope in the treatment of intestinal failure (LF) associated with the Short Bowel Syndrome (SBS)...
- Outcome and long-term growth after extensive small bowel resection in the neonatal period: a survey of 87 childrenO Goulet
Gastroenterology and Nutrition Department, Hopital des Enfants Malades, Paris, France
Eur J Pediatr Surg 15:95-101. 2005..This retrospective study aims to analyze the outcome, the prognosis factors and the long-term growth of children after extensive small bowel (SB) resection in the neonatal period...
- Intestinal growth in parenterally-fed rats induced by the combined effects of glucagon-like peptide 2 and epidermal growth factorPaul A Kitchen
St Mark's Hospital, Imperial College London, Harrow, United Kingdom
JPEN J Parenter Enteral Nutr 29:248-54. 2005..thus have the potential to benefit patients fed parenterally, such as those with intestinal failure from short bowel syndrome. We report studies aimed to determine whether there may be synergistic effects of these 2 peptides...
- Serial transverse enteroplasty is associated with successful short-term outcomes in infants with short bowel syndromePatrick J Javid
Department of Surgery, Children's Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
J Pediatr Surg 40:1019-23; discussion 1023-4. 2005..serial transverse enteroplasty (STEP) has been shown to improve nutritional indices in an animal model of short bowel syndrome. The aim of this study was to review short-term surgical and nutritional outcomes in the first cohort of ..
- Management of intestinal failureK Soondrum
Department of Child Health, King's College Hospital, London, United Kingdom
Indian J Pediatr 73:913-8. 2006..Prolonged IF is seen after large intestinal resection and described as short bowel syndrome (SBS)...
- Effects of the combined use of glutamine and growth hormone in the intestinal adaptation after massive resection of the small bowel in ratsJoaquim M Spadoni
Department of Surgery, University of Cuiab
Acta Cir Bras 20:382-9. 2005..01). There was a significant increase in the intestinal wall width and crypt depth in the control group (p < 0.01). CONCLUSION: Gut adaptation after massive resection is improved with the combined use of glutamine and GH...
- Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndromeXiaowen Liu
Department of Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, USA
Am J Clin Nutr 84:1142-50. 2006BACKGROUND: Short bowel syndrome (SBS) can lead to intestinal failure and require total or supplemental parenteral nutrition (TPN or PN, respectively)...
- Acellular dermal matrix provides a good option for abdominal wall closure following small bowel transplantation: a case reportE Asham
Department of Surgery, Division of Organ Transplantation, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Transplant Proc 38:1770-1. 2006..This is the first report of the use of ADM for abdominal closure in patients receiving a SBTx. ADM is considered safe when used in contaminated sites and can allow primary closure of difficult wounds often seen in SBTx patients...
- [Extensive small bowel resections]Filippo Ferrarese
UO Chirurgia Generale IV, Dipartimento di Scienze Chirurgiche Generali e Specialistiche,
Chir Ital 57:631-4. 2005..In more extensive resections, involving a longer adaptation time, enteral nutrition was supplemented with total parenteral nutrition for lengthier periods...
- Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal pigletsAnne L Bartholome
Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
JPEN J Parenter Enteral Nutr 28:210-22; discussion 222-3. 2004..Ultimately, butyrate administration may enable an infant with short-bowel syndrome to successfully transition to enteral feedings by maximizing their absorptive area...
- Intestinal adaptation after massive intestinal resectionA R Weale
Department of Surgery, Southmead Hospital, North Bristol NHS Hospitals Trust, Westbury on Trym, Bristol BS10 5NB, UK
Postgrad Med J 81:178-84. 2005Patients with short bowel syndrome require long term parenteral nutrition support. However, after massive intestinal resection the intestine undergoes adaptation and nutritional autonomy may be obtained...
- Surgical therapy for short bowel syndromePaul W Wales
Division of General Surgery, The Hospital for Sick Children, 555 University Avenue, Rm 1526, Toronto, Ontario M5G 1X8, Canada
Pediatr Surg Int 20:647-57. 2004Patients with short bowel syndrome (SBS) suffer tremendous morbidity secondary to prolonged hospitalization and chronic parenteral nutrition (TPN)...
- The nutritional management of short bowel syndromeChristian S Jackson
Division of Gastroenterology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Nutr Clin Care 7:114-21. 2004b>Short bowel syndrome (SBS) is the predominant cause of intestinal failure and is associated with a high degree of morbidity and mortality. One of the reasons this occurs is because of the dramatic reduction in nutrient absorptive capacity...
- [Clinical results of intestinal and multivisceral transplantation at the Charité, Berlin. A case series]A Pascher
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie
Dtsch Med Wochenschr 130:387-92. 2005Intestinal transplantation (ITx) is the only causal therapy of short bowel syndrome (SBS). Long-term survival after ITx has been improved significantly during the last years...
- Irreversible intestinal failureOlivier Goulet
Département de gastroentérologie, Hépatologie et Nutrition Pédiatriques, Hôpital Necker Infants Malades and INSERM, Faculté de Necker, Paris, France
J Pediatr Gastroenterol Nutr 38:250-69. 2004..b>Short bowel syndrome was the first commonly recognized cause of protracted IF...
- Gut hormones, and short bowel syndrome: the enigmatic role of glucagon-like peptide-2 in the regulation of intestinal adaptationG R Martin
Department of Gastrointestinal Sciences, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
World J Gastroenterol 12:4117-29. 2006b>Short bowel syndrome (SBS) refers to the malabsorption of nutrients, water, and essential vitamins as a result of disease or surgical removal of parts of the small intestine...
- Superior mesenteric vein thrombosis after colectomy in a patient with Crohn's diseaseAndrew S Ross
Department of Surgery, University of Chicago, IL, USA
Nat Clin Pract Gastroenterol Hepatol 2:281-5; quiz 1 p following 285. 2005..DIAGNOSIS: Acute mesenteric ischemia secondary to superior mesenteric vein thrombosis. MANAGEMENT: Resection of necrotic bowel, antibiotics and systemic anticoagulation...
- Total parenteral nutrition, intestinal adaptation, and short bowel syndromeHerbert R Freund
Department of Surgery, Hadassah University Hospital Mount Scopus and Hebrew University, Hadassah Medical School, Jerusalem, Israel
Nutrition 20:337. 2004
- Late regeneration of infarcted small bowel mucosa: a case reportOded Zmora
Department of Surgery and Transplantation, Sheba Medical Center, Sackler School of Medicine, Tel Aviv, Israel
JPEN J Parenter Enteral Nutr 29:131-3. 2005..Sixteen months after the injury, normal mucosa covered the entire small bowel, and enteral feeding resumed successfully. This report shows that infarcted small-bowel mucosa may regenerate even months after injury...
- Glucagon-like peptide-2 induces a specific pattern of adaptation in remnant jejunumD L Sigalet
University of Calgary, Gastrointestinal Research Group, Calgary, Alberta, Canada
Dig Dis Sci 51:1557-66. 2006..Herein we investigate the effects of GLP-2 on the jejunal remant using a rat model of short bowel syndrome (SBS)...
- [Massive intestinal resection: Nutricional adaptation process]J M Moreno Villares
Nutr Hosp 23:171-2; author reply 172. 2008
- Long-term outcome, growth and digestive function in children 2 to 18 years after intestinal transplantationF Lacaille
Pediatric Gastroenterology Hepatology Nutrition Unit, Necker Enfants Malades Hospital, 149 rue de Sevres, 75015 Paris, France
Gut 57:455-61. 2008..In this retrospective study, we analysed graft functions in 31 children after SBTx with a follow-up of 2-18 years (median 7 years)...
- New dietary concepts in small bowel transplantationR-J Schulz
Hepatology, Gastroenterology, Charit, Campus Virchow Klinikum, , 13353, Berlin, Germany
Transplant Proc 34:893-5. 2002
- Role of extrinsic innervation in jejunal absorptive adaptation to subtotal small bowel resection: a model of segmental small bowel transplantationKaren D Libsch
Gastroenterology Research Unit and Department of Surgery, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
J Gastrointest Surg 6:240-7. 2002..The extrinsic denervation necessitated by small bowel transplantation does not appear to blunt the net jejunal adaptive response to total ileal resection, but may temporarily alter glutamine absorption...
- Distribution of the H+/peptide transporter PepT1 in human intestine: up-regulated expression in the colonic mucosa of patients with short-bowel syndromeThomas R Ziegler
Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA
Am J Clin Nutr 75:922-30. 2002..Intestinal adaptation after massive bowel resection in animal models is characterized by increased gut-mucosal growth and expression of nutrient transporters. Few data about these indexes exist in humans with short-bowel syndrome (SBS)...
- Impairment of arginine metabolism in rats after massive intestinal resection: effect of parenteral nutrition supplemented with citrulline compared with arginineSylwia Osowska
Laboratoire de Biologie de la Nutrition, EA 2498, Faculté de Pharmacie Université Paris Descartes, 4 avenue de l Observatoire, 75270 Paris Cedex 06, France
Clin Sci (Lond) 115:159-66. 2008Arginine homoeostasis is impaired in short bowel syndrome, but its supplementation in short bowel syndrome patients remains controversial...
- Does ileal reverse segment in rats with short bowel syndrome change intestinal morphology?Aydin Sencan
Department of Pediatric Surgery, Faculty of Medicine of Celal Bayar University, Manisa, Turkey
J Pediatr Gastroenterol Nutr 34:165-8. 2002The primary goal of surgical therapy for short bowel syndrome is to increase intestinal absorptive capacity. Many surgical procedures have been described for this purpose. One of these is ileal reverse-segment procedure...
- Clinical outcome in patients from a single region who were dependent on parenteral nutrition for 28 days or moreJ Koglmeier
Department of Paediatric Gastroenterology, Chelsea and Westminster Hospital, 369 Fulham Road, London SW10 9NH
Arch Dis Child 93:300-2. 2008..The ideal model for service provision is a subject of debate...
- The management of patients with the short bowel syndromeCameron F E Platell
Department of Surgery, The University of Western Australia, Perth, Australia
World J Gastroenterol 8:13-20. 2002The surgeon is invariably the primary specialist involved in managing patients with short bowel syndrome. Because of this they will play an important role in co-ordinating the management of these patients...
- Effect of bowel rehabilitative therapy on structural adaptation of remnant small intestine: animal experimentX Zhou
Research Institute of General Surgery, Chinese PLA General Hospital of Nanjing Military Area, 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China
World J Gastroenterol 7:66-73. 2001..Enteral glutamine perfusion is beneficial in preserving small bowel mucosal structure during TPN, but has little beneficial effect during EN...
- Effect of IGF-rich colostrum on bowel adaptation in neonatal piglets with short bowel syndromeV H Heemskerk
Department of Surgery, the University of Maastricht, Maastricht, The Netherlands
J Pediatr Gastroenterol Nutr 34:47-51. 2002..this study was that colostrum rich in IGF-1 could promote small bowel adaptation in neonatal piglets with short bowel syndrome. METHODS: Twenty-four piglets, aged 7 days, underwent 75% small bowel resection and were fed 525 kJ x kg(-1)..
- Intestinal function and metabolism in the early adaptive phase after massive small bowel resection in the ratC F Welters
Department of Surgery, University Hospital Maastricht, Maastricht University, Maastricht, The Netherlands
J Pediatr Surg 36:1746-51. 2001..This, however, is accompanied by an increase in intestinal permeability, which may indicate impaired intestinal barrier function. J Pediatr Surg 36:1746-1751...
- Long-term cognitive functions in neonatal short bowel syndrome patientsJ Huang
Clinical Nutrition Center, Shanghai Jiao Tong University, School of Medicine, Xin Hua Hospital, Shanghai, China
Eur J Pediatr Surg 18:89-92. 2008The aim of the study was to evaluate the long-term effects of neonatal short bowel syndrome on cognitive functions during development.
- Fasting plasma citrulline concentrations do not reflect intestinal absorption capacityJob H C Peters
JPEN J Parenter Enteral Nutr 32:288; author reply 289. 2008
- Novel effect of leptin on small intestine adaptationP Y Pearson
Department of Surgery, A.I. duPont Hospital for Children, Wilmington, Delaware 19899, USA
J Surg Res 97:192-5. 2001..Leptin may be clinically useful in patients with inadequate intestinal function...
- Pediatric intestinal failure: nutrition, pharmacologic, and surgical approachesY Avery Ching
Children s Hospital of Boston, Department of Surgery, Fegan 3, 300 Longwood Avenue, Boston, MA 02115, USA
Nutr Clin Pract 22:653-63. 2007..IF is a difficult disease process with a complex patient population and is best guided through this 3-pronged approach by a multidisciplinary team featuring surgeons, gastroenterologists, dietitians, pharmacists, and nurses...
- Short bowel syndromeJames S Scolapio
JPEN J Parenter Enteral Nutr 26:S11-6. 2002
- Intermediate outcomes after serial transverse enteroplasty in children with short bowel syndromePaul W Wales
Division of General Surgery, The Hospital for Sick Children, Toronto, Canada M5G 1X8
J Pediatr Surg 42:1804-10. 2007..The aim of this study was to report intermediate outcomes in patients who have received the STEP at our institution using clinical and biochemical assessment of intestinal function...
- New and emerging therapies for short bowel syndrome in childrenJon A Vanderhoof
Department of Pediatric Gastroenterology and Nutrition, University of Nebraska Medical Center, Omaha, Nebraska 68198 5160, USA
Paediatr Drugs 5:525-31. 2003..provides an overview of traditional as well as emerging therapies useful in the management of pediatric short bowel syndrome. Pediatric short bowel syndrome is relatively uncommon; however, when it does occur, it presents a unique ..
- Promoting intestinal adaptationKatharina Wallis
Lennard Jones Intestinal Failure Unit, St Mark's Hospital, Harrow
Br J Hosp Med (Lond) 68:11-4. 2007
- AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTIONHARRY SAX; Fiscal Year: 2004b>Short bowel syndrome is a devastating clinical condition which leads to dehydration, muscle wasting, debilitation and death...
- NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATIONMarc Levin; Fiscal Year: 2009DESCRIPTION (provided by investigator): Short bowel syndrome resulting from diminished intestinal absorptive function is a major cause of morbidity and impaired quality of life...
- Short-Chain Fatty Acid Enhanced Intestinal AdaptationKELLY TAPPENDEN; Fiscal Year: 2006..abstract_text> ..
- Mechanisms of Intestinal Stem Cell Expansion Following ResectionMichael A Helmrath; Fiscal Year: 2009..The increased incidence of chronic short bowel syndrome (SBS) in these patients suggests that TPN-feeding may attenuate the normal adaptive ISC expansion...
- Mechanisms of Intestinal Stem Cell Expansion Following ResectionMichael A Helmrath; Fiscal Year: 2010..The increased incidence of chronic short bowel syndrome (SBS) in these patients suggests that TPN-feeding may attenuate the normal adaptive ISC expansion...
- TOTAL PARENTERAL NUTRITION AND INTESTINAL ADAPTIONDenise Ney; Fiscal Year: 2006b>Short bowel syndrome often requires permanent total parenteral nutrition. Current treatment is inadequate because TPN induces serious complications and is expensive...
- Novel Polymers for Tissue EngineeringROBERT SAMUEL LANGER; Fiscal Year: 2010b>Short Bowel Syndrome (SBS) is a devastating clinical disorder that has a high prevalence of mortality and morbidity and takes a severe socioeconomic toll on patients...
- NUTRIENT MODULATION OF GENE EXPRESSION IN GUT ADAPTATIONMarc Levin; Fiscal Year: 2007b>Short bowel syndrome resulting from diminished intestinal absorptive function is a major cause of morbidity and impaired quality of life...
- Enterocyte Apoptosis after Intestinal ResectionBrad Warner; Fiscal Year: 2006..The long-term goal of this project is to optimize therapy for patients with the short bowel syndrome by delineating the significance of enterocyte apoptosis during intestinal adaptation...
- Parenteral Nutrition: Intestinal Metabolism/AdaptationDenise Ney; Fiscal Year: 2009b>Short bowel syndrome (SBS) often requires parenteral nutrition (PN)...
- Physiological role of GLP-2 receptor in the mouse intestinal growth and functionXinfu Guan; Fiscal Year: 2007..g. short bowel syndrome), which may facilitate to develop new drugs to treat intestinal disease/ dysfunction...
- CELL CYCLE REGULATION IN INTESTINAL REGENERATIONEdward Whang; Fiscal Year: 2004..The long-term goal of this proposal is to develop new strategies for treating patients suffering from the short bowel syndrome. Chronic total parenteral nutrition and intestinal transplantation are currently the only available options ..
- Enterogenesis with the Use of an Implanted Mechanotransduction DeviceDaniel Teitelbaum; Fiscal Year: 2007b>Short bowel syndrome (SBS) is a devastating surgical disease with a high morbidity and mortality. SBS results in a series of adaptive processes, including proliferation, apoptosis, and increased absorptive capacity...
- Stem cell-based renewal and regeneration in the intestine of a model organismDAVID FORSTHOEFEL; Fiscal Year: 2006..g. short bowel syndrome) would be clinically beneficial...