Genomes and Genes
Summary: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)
Publications274 found, 100 shown here
- Hypocalcemia-associated coronary vasospasmPatrick C Magnus
Department of Internal Medicine, St Vincent s Medical Center, Bridgeport, CT 06606, USA
Conn Med 69:3-7. 2005
- Careful examination of thyroid specimen intraoperatively to reduce incidence of inadvertent parathyroidectomy during thyroid surgeryBassam Abboud
Department of General Surgery, Hotel Dieu de France Hospital, Alfred Naccache Street, Beirut, Lebanon
Arch Otolaryngol Head Neck Surg 133:1105-10. 2007..To assess the incidence and clinical relevance of inadvertent parathyroidectomy during thyroidectomy, and the possibility of reducing its occurrence...
- Postoperative hypocalcemia after thyroidectomy for Graves' diseaseCatherine E Pesce
Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Thyroid 20:1279-83. 2010..that patients who undergo thyroidectomy for Graves' disease are more likely to experience postoperative hypocalcemia than patients undergoing total thyroidectomy for other indications...
- Intraoperative parathyroid hormone assay for management of patients undergoing total thyroidectomyJong Lyel Roh
Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 388 1, Pungnap dong, Songpa Gu, Seoul 138 736, Korea
Head Neck 28:990-7. 2006Rapid parathyroid hormone (PTH) assay has been applied to predict hypocalcemia after thyroidectomy compared with conventional close monitoring of serum calcium levels...
- Inadvertent parathyroid excision during thyroid surgeryT E Rix
Department of General Surgery, William Harvey Hospital, Ashford, Kent, UK
Surgeon 4:339-42. 2006..We aimed to establish the incidence of parathyroid gland excision during surgery for thyroid disease and whether there was an effect on calcium control in patients in whom inadvertent parathyroidectomy had occurred...
- Prevention of postoperative hypocalcemia with routine oral calcium and vitamin D supplements in patients with differentiated papillary thyroid carcinoma undergoing total thyroidectomy plus central neck dissectionJong Lyel Roh
Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Cancer 115:251-8. 2009..The authors therefore prospectively evaluated the clinical usefulness of routine oral calcium and vitamin D supplementation for prevention of hypocalcemia after total thyroidectomy and CND.
- Treatment and control of peri-parturient metabolic diseases: pregnancy toxemia, hypocalcemia, hypomagnesemiaChristos Brozos
School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece
Vet Clin North Am Food Anim Pract 27:105-13. 2011..Treatment of hypocalcemia is based on administration of calcium solution...
- Loss of seizure control due to anticonvulsant-induced hypocalcemiaFawzi Elhami Ali
Medical Rehabilitation Center, PO Box 1240, Surra 45713, Kuwait
Ann Pharmacother 38:1002-5. 2004To report a case of loss of seizure control due to hypocalcemia resulting from long-term treatment with phenytoin and phenobarbital.
- Early prediction of hypocalcemia after thyroidectomy using parathyroid hormone: an analysis of pooled individual patient data from nine observational studiesJ Pieter Noordzij
Department of Otolaryngology Head and Neck Surgery, Boston University Medical Center, Boston, MA, USA
J Am Coll Surg 205:748-54. 2007Monitoring for hypocalcemia after thyroidectomy, using only symptoms and serum calcium levels, can delay the discharge of patients who will remain normocalcemic and can delay the treatment of hypocalcemic patients.
- Predicting calcium status post thyroidectomy with early calcium levelsMurad Husein
Department of Otolaryngology Head and Neck Surgery, Jewish General Hospital, McGill University, Montreal, Canada
Otolaryngol Head Neck Surg 127:289-93. 2002The study goals were to predict postoperative normocalcemia and hypocalcemia after total thyroidectomy using calcium levels and to assess the value of a standardized protocol in managing the total thyroidectomy patient.
- Evaluation of serum calcium levels in predicting hypoparathyroidism after total/near-total thyroidectomy or parathyroidectomyD J Bentrem
Division of Gastrointestinal and Endocrine Surgery, Northwestern University Medical School, Chicago, Illinois, USA
Am Surg 67:249-51; discussion 251-2. 2001..Strategies to recognize hypocalcemia postoperatively vary...
- The predictive value of perioperative calcium levels after thyroid/parathyroid surgeryQuang Luu
Department of Otolaryngology Head and Neck Surgery, Oregon Health Sciences University, PV 01, 3181 SW Sam Jackson Park Road, Portland, OR 97201 USA
Head Neck 24:63-7. 2002This work was done to determine whether the slope of change between preoperative and early postoperative (2 hr and 8 hr) ionized calcium levels (ciCa) could predict significant postoperative hypocalcemia.
- Incidental parathyroidectomy during thyroid surgery does not cause transient symptomatic hypocalcemiaA R Sasson
Head and Neck Surgery Section, Fox Chase Cancer Center, 7701 Burholme Ave, Philadelphia, PA 19111, USA
Arch Otolaryngol Head Neck Surg 127:304-8. 2001..any risk factors for incidental parathyroidectomy and to define its association with symptomatic postoperative hypocalcemia. DESIGN: Retrospective study. SETTING: Tertiary referral cancer center...
- Myocardial dysfunction due to hypocalcemiaMunesh Tomar
Department of Pediatrics and Congenital Heart Surgery, Escorts Heart Institute and Research Centre, Okhla Road, New Delhi 110 025, India
Indian Pediatr 47:781-3. 2010b>Hypocalcemia is a curable cause of myocardial dysfunction and clinical congestive cardiac failure, with only stray reports available in literature...
- Amikacin-induced type 5 Bartter-like syndrome with severe hypocalcemiaA Chrispal
Department of Medicine II, Christian Medical College, Vellore, India
J Postgrad Med 55:208-10. 2009..renal tubular dysfunction secondary to short-term therapy with Amikacin, resulting in refractory hypokalemia, hypocalcemia, hypomagnesemia, metabolic alkalosis, and polyuria...
- Early prediction of postthyroidectomy hypocalcemia by one single iPTH measurementCelestino Pio Lombardi
Division of Endocrine Surgery, Department of Surgery, Catholic University of the Sacred Heart, Largo A Gemelli 8, 00168 Rome, Italy
Surgery 136:1236-41. 2004We prospectively evaluated the possibility to make an early prediction of postthyroidectomy hypocalcemia by postoperative intact parathyroid hormone (iPTH) measurements.
- Evidence for the role of perioperative PTH measurement after total thyroidectomy as a predictor of hypocalcemiaSimon Grodski
The Alfred Hospital, Monash University Endocrine Surgery Unit, Melbourne, Vic, 3144, Australia
World J Surg 32:1367-73. 2008..b>Hypocalcemia is the most common complication of that procedure and a variety of strategies for diagnosing and managing post-..
- Calcium homeostasis and parturient hypocalcemia: an integral feedback perspectiveH El-Samad
Electrical and Computer Engineering, Iowa State University, Ames, IA 50011, USA
J Theor Biol 214:17-29. 2002..We show that the model is biologically plausible and is consistent with known physiology. Furthermore, the utility of the integral-feedback model is revealed by examining an extreme calcium perturbation, parturient paresis in dairy cows...
- Systematic review and meta-analysis of the adverse effects of thyroidectomy combined with central neck dissection as compared with thyroidectomy aloneEdward J Chisholm
Department of ENT and Thyroid Surgery, St Mary s Hospital, Imperial College Hospitals NHS Trust, London, UK
Laryngoscope 119:1135-9. 2009..Meta-analysis to assess the increased morbidity of performing a central neck dissection with thyroidectomy to thyroidectomy alone...
- Ligasure versus Ultracision in thyroid surgery: a prospective randomized studyPaola Vincenza Sartori
Surgical Department, S Gerardo Hospital, University of Milan Bicocca, Via Pergolesi 33, 20052, Monza, Italy
Langenbecks Arch Surg 393:655-8. 2008..New hemostatic technologies (NT) are often employed in thyroid surgery in the effort to reduce operating time and complications. The aim of this study is to compare three different hemostatic techniques...
- Routine oral calcium and vitamin D supplements for prevention of hypocalcemia after total thyroidectomyJong Lyel Roh
Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 388 1 Pungnap dong, Songpa Gu, Seoul 138 736 Republic of Korea
Am J Surg 192:675-8. 2006The purpose of this study was to evaluate the clinical usefulness of routine oral calcium and vitamin D supplements in the prevention of hypocalcemia after total thyroidectomy.
- Complete DiGeorge anomaly in the absence of neonatal hypocalcemia and velofacial and cardiac defectsSalem Al-Tamemi
Division of Allergy and Immunology, Montreal Children s Hospital, McGill University Health Center, Montreal, Quebec, Canada
Pediatrics 116:e457-60. 2005..Importantly, the child presented without neonatal hypocalcemia or velofacial or cardiac abnormalities at the time of diagnosis, which masked underlying DG...
- Excessive decrease in serum magnesium after total thyroidectomy for Graves' disease is related to development of permanent hypocalcemiaSara Salehi Hammerstad
The Hormone Laboratory, Oslo University Hospital Aker, Postbox 4959, Nydalen, 0424 Oslo, Norway
World J Surg 37:369-75. 2013Transient postoperative hypocalcemia is one of the most common complications after thyroidectomy. Permanent hypocalcemia, however, is rare, but usually requires life-long treatment and follow-up...
- A review of drug-induced hypocalcemiaGeorge Liamis
Department of Internal Medicine, School of Medicine, University of Ioannina, 451 10 Ioannina, Greece
J Bone Miner Metab 27:635-42. 2009b>Hypocalcemia (defined as total serum calcium lower than 8.5 mg/dl or as ionized serum calcium lower than 4.7 mg/dl) is a relatively common metabolic abnormality observed in hospitalized patients...
- Parathyroid hormone 7-84 induces hypocalcemia and inhibits the parathyroid hormone 1-84 secretory response to hypocalcemia in rats with intact parathyroid glandsJinxing Huan
Nephrological Department P, Rigshospitalet, Herlev Hospital, University of Copenhagen, DK 2730 Herlev, Denmark
J Am Soc Nephrol 17:1923-30. 2006..Furthermore, the PTH 1-84 secretory response to EGTA-induced acute and severe hypocalcemia was significantly inhibited by PTH 7-84...
- The impact of age, vitamin D(3) level, and incidental parathyroidectomy on postoperative hypocalcemia after total or near total thyroidectomyYesim Erbil
Department of General Surgery, Istanbul University Istanbul Medical Faculty, Istanbul, Turkey
Am J Surg 197:439-46. 2009b>Hypocalcemia caused by transient or definitive hypoparathyroidism is the most frequent complication after thyroidectomy...
- Is routine supplementation therapy (calcium and vitamin D) useful after total thyroidectomy?Rocco Bellantone
Division of Endocrine Surgery, Department of Surgery, Universita Cattolica del Sacro Cuore, Largo A Gemelli 8, 00168 Rome, Italy
Surgery 132:1109-12; discussion 1112-3. 2002Our goal was to determine whether routine oral calcium (OC) and vitamin D (VD) administration can effectively prevent symptoms of hypocalcemia after total thyroidectomy.
- Parathyroid hormone secretion in women in late menopause submitted to EDTA-induced hypocalcemiaL C R Pereira
Department of Gynecology and Obstetrics, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Avenue Bandeirantes 3900, Ribeirao Preto, Sao Paulo, Brazil
Maturitas 59:91-4. 2008..9 years, N=7) and in women in late menopause (Group M=64.7 years, N=7) and their relationship to bone mineral density...
- Postoperative hypocalcemia--the difference a definition makesHisham M Mehanna
Institute of Head and Neck Studies and Education, University Hospital, Coventry, United Kingdom
Head Neck 32:279-83. 2010..literature reveals considerable variability in the definitions and criteria used for reporting postoperative hypocalcemia. The lack of standardization prevents a meaningful comparison of results and performance locally with the ..
- A prospective evaluation of quick intraoperative parathyroid hormone assay at the time of skin closure in predicting clinically relevant hypocalcemia after thyroidectomyBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong SAR, China
World J Surg 36:1300-6. 2012Post-thyroidectomy hypocalcemia is a major contributing factor in delayed hospital discharge and dissuading surgeons from ambulatory thyroidectomy...
- Efficacy of an intravenous calcium gluconate infusion in controlling serum calcium after parathyroidectomy for secondary hyperparathyroidismSeng Cheong Loke
Universiti Putra Malaysia, Selangor, Malaysia
Ann Acad Med Singapore 38:1074-80. 2009..Intravenous calcium gluconate has been used to prevent postoperative hypocalcaemia (POH) following parathyroidectomy for secondary hyperparathyroidism in chronic kidney disease (CKD)...
- Ionized calcium concentration and outcome in critical illnessMoritoki Egi
Department of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama, Japan
Crit Care Med 39:314-21. 2011..To assess the association of abnormalities of ionized calcium levels with mortality in a heterogeneous cohort of critically ill patients...
- Postoperative PTH measurement as a predictor of hypocalcaemia after thyroidectomyM Proczko-Markuszewska
Dept of General, Endocrine and Transplant Surgery, Medical Univ of Gdansk, Poland
Acta Chir Belg 110:40-4. 2010..There is a variety of proposed options for the prediction of the incidence of hypocalcaemia. The most effective of them are the peri-operative and intra-operative measurements of the parathyroid hormone (PTH) level...
- Effects of hypocalcemia on electrical restitution and ventricular fibrillationMark L Ricco
Department of Biomedical Sciences, Cornell University, Ithaca, NY 14853, USA
Conf Proc IEEE Eng Med Biol Soc 2009:4182-5. 2009..slope, as opposed to alteration of calcium dynamics unrelated to restitution, we tested the effects of hypocalcemia ([CaCl2]=31-125 microM) in canine ventricle. At normal [CaCl2] (2...
- Idiopathic hypoparathyroidism presenting with severe hypocalcemia and asymptomatic basal ganglia calcification followed by acute intracerebral bleedNirav Mamdani
The Division of Endocrinology, Diabetes, and Metabolism, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Endocr Pract 13:487-92. 2007To report a case of idiopathic hypoparathyroidism presenting with severe hypocalcemia and intracerebral calcifications that resulted in a spontaneous intracerebral bleed.
- Does near total thyroidectomy offer advantage over total thyroidectomy in terms of postoperative hypocalcemia?Haluk Recai Unalp
Ataturk Training and Research Hospital, General Surgery Clinic, Izmir, Turkey
Int J Surg 7:120-5. 2009..calcium levels before and after total and near total thyroidectomy and to compare the rate of postoperative hypocalcemia according to surgical procedures...
- Risk factors contributing to the development of hypocalcemia after zoledronic acid administration in patients with bone metastases of solid tumorMiho Hanamura
Department of Pharmacy, Mie University Hospital, Faculty of Medicine, Mie University, USA
Biol Pharm Bull 33:721-4. 2010..Although hypocalcemia often develops by ZDA, there is little information about the risk factors for hypocalcemia mediated by ZDA...
- Treatment of hypocalcemia caused by hypoparathyroidism or pseudohypoparathyroidism with domestic-made calcitriol: a prospective and self-controlled clinical trialOu Wang
Department of Endocrinology, Key Lab of Endocrinology Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China
Chin Med J (Engl) 122:279-83. 2009Parathyroid hormone deficiency or resistance may cause hypocalcemia with related symptoms and signs. Lifelong treatment of calcium combined with vitamin D or its metabolites is always necessary for these patients...
- Serum PTH and ionized calcium levels as predictors of symptomatic hypocalcemia after parathyroidectomyKashif A Zuberi
Department of General Surgery, Marshfield Clinic and St Joseph s Hospital, Marshfield, Wisconsin 54449, USA
Laryngoscope 120:S192. 2010..To evaluate whether perioperative PTH levels or ionized calcium levels are associated with symptomatic hypocalcaemia, in patients undergoing parathyroidectomy for primary hyperparathyroidism...
- Bisphosphonate pretreatment attenuates hungry bone syndrome postoperatively in subjects with primary hyperparathyroidismI Te Lee
Division of Endocrinology and Metabolism, Taichung Veterans General Hospital, No 160, Sec 3, Chung Kang Road, Taichung 407, Taiwan, ROC
J Bone Miner Metab 24:255-8. 2006Primary hyperparathyroidism is characterized by hypercalcemia with loss of bone mass. After parathyroidectomy, hypocalcemia may develop in some patients due to unregulated bone mineralization...
- Deaths resulting from hypocalcemia after administration of edetate disodium: 2003-2005Mary Jean Brown
Lead Poisoning Prevention Branch, Division of Emergency and Environmental Health Services, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
Pediatrics 118:e534-6. 2006From 2003 to 2005, deaths of 3 individuals as a result of cardiac arrest caused by hypocalcemia during chelation therapy were reported to the Centers for Disease Control and Prevention...
- Treatment of hypocalcemia in critical illness--part 2Roland N Dickerson
Department of Clinical Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee, USA
Nutrition 23:436-7. 2007
- Novel gain of function mutations of the calcium-sensing receptor in two patients with PTH-deficient hypocalcemiaKishiko Nakajima
Department of Medicine, Institute of Clinical Endocrinology, Tokyo Women s Medical University, Tokyo
Intern Med 48:1951-6. 2009Among 15 patients with PTH-deficient idiopathic hypocalcemia, we found two novel missense mutations in the calcium-sensing receptor (CaSR). Patient 1, who developed severe hypocalcemia (5...
- Hypocalcemia: updates in diagnosis and management for primary careJeremy Fong
Queen s University in Kingston, Ontario, Canada
Can Fam Physician 58:158-62. 2012To provide family physicians with an evidence-based approach to the diagnosis and management of hypocalcemia. Quality of evidence MEDLINE and EMBASE articles from 2000 to 2010 were searched, with a focus on the diagnosis and management of ..
- CASR gene activating mutations in two families with autosomal dominant hypocalcemiaVito Guarnieri
Medical Genetics, IRCCS Casa Sollievo della Sofferenza Hospital, Viale Padre Pio, 71013 San Giovanni Rotondo, FG, Italy
Mol Genet Metab 107:548-52. 2012Autosomal dominant hypocalcemia (ADH) is an endocrine disorder caused by activating mutations of the calcium-sensing receptor (CASR) gene which plays a major role in maintaining calcium homeostasis...
- Incidental extirpation of the parathyroid glands at thyroid surgery: risk factors and post-operative hypocalcemiaGhazi Raji Qasaimeh
Department of General Surgery Medical College, King Abdullah University Hospital, Jordan University of Science and Technology, PO Box 1592, Irbid, Jordan
Eur Arch Otorhinolaryngol 268:1047-51. 2011..Incidence of incidental extirpation of the parathyroid glands during thyroid operations and post-thyroidectomy hypocalcemia were reviewed. Results showed that incidental parathyroidectomy occurred in 8.6%...
- Complications in primary and completed thyroidectomyMichael Vaiman
Department of Otorhinolaryngology, Head and Neck Surgery, Assaf Harofeh Medical Center Sackler Faculty of Medicine, Tel Aviv University, Zerifin, Israel
Surg Today 40:114-8. 2010..To compare the rates of postsurgical complications following a primary and completed thyroidectomy for multinodular goiter (MNG)...
- The role of rapid PACU parathyroid hormone in reducing post-thyroidectomy hypocalcemiaSarmad Sabour
Department of Otolaryngology Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio 45267 0528, USA
Otolaryngol Head Neck Surg 141:727-9. 2009Post-thyroidectomy parathyroid hormone (PTH) levels have been used to predict hypocalcemia. The goal of this study was to determine whether selective supplementation for post anesthesia care unit (PACU) PTH < 15 mg/dL reduced ..
- Intraoperative parathyroid hormone levels in thyroid surgery are predictive of postoperative hypoparathyroidism and need for vitamin D supplementationRoderick M Quiros
Department of General Surgery, Rush University Medical Center, 1653 W Congress Pkwy, Chicago, IL 60612 3833, USA
Am J Surg 189:306-9. 2005..This prospective study evaluated the occurrence of hypoparathyroidism after thyroid surgery and the use of ioPTH levels to predict the need for postoperative vitamin D supplementation...
- The effects of salmon calcitonin-induced hypocalcemia on bone metabolism in ovariectomized ratsRachel A Davey
Hanson Institute, Frome Road, Adelaide, South Australia, Australia
J Bone Miner Metab 23:359-65. 2005..001). Increased parathyroid hormone (PTH) levels (P < 0.001) accompanied the hypocalcemia in ovx rats...
- Impaired parathyroid hormone response to hypocalcemic stimuli in a patient with hypomagnesemic hypocalcemiaY Iwasaki
Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Kochi University, Kohasu, Oko cho, Nankoku 783 8505, Japan
J Endocrinol Invest 30:513-6. 2007Magnesium (Mg) deficiency sometimes causes hypocalcemia with impaired PTH secretion although the precise mechanism remains unclear...
- Prolactin prevents acute stress-induced hypocalcemia and ulcerogenesis by acting in the brain of ratTakahiko Fujikawa
Department of Biochemistry, Faculty of Medicine, Mie University, Japan
Endocrinology 145:2006-13. 2004Stress causes hypocalcemia and ulcerogenesis in rats...
- Prospective study of perioperative factors predicting hypocalcemia after thyroid and parathyroid surgeryStanley H Chia
Division of Head and Neck Surgery, University of California San Diego, USA
Arch Otolaryngol Head Neck Surg 132:41-5. 2006To identify whether perioperative 1,25-dihydroxyvitamin D or parathyroid hormone (PTH) levels will predict the development of hypocalcemia after thyroid and parathyroid surgery.
- Serum intact parathyroid hormone as a predictor of hypocalcaemia after total thyroidectomyPatsy S H Soon
Endocrine Surgical Unit, St George Hospital, New South Wales, Australia
ANZ J Surg 75:977-80. 2005..The aim of the present study was to determine whether an early postoperative level of serum parathyroid hormone (PTH) after total thyroidectomy predicts the development of significant hypocalcaemia and the need for treatment...
- Teriparatide efficacy in the treatment of severe hypocalcemia after kidney transplantation in parathyroidectomized patients: a series of five case reportsEstela L Nogueira
Department of Nephrology and Renal Transplantation, Hospital de Santa Maria, Centro Hospitalar Lisboa Norte, Lisboa, Portugal
Transplantation 92:316-20. 2011..In this study, we analyze the efficacy and safety profile of teriparatide therapy in severe and prolonged hypocalcemia after kidney transplantation in patients previously submitted to parathyroidectomy.
- Hypoparathyroidism after total thyroidectomy: a prospective studyReza Asari
Medical University of Vienna, Waehringer Guertel 18 20, Vienna A 1080, Austria
Arch Surg 143:132-7; discussion 138. 2008Combined measurement of intact parathyroid hormone (iPTH) and serum calcium (sCa) levels is useful for predicting postoperative hypocalcemia with minimal laboratory effort and low costs.
- Randomized clinical trial on Harmonic Focus shears versus clamp-and-tie technique for total thyroidectomyMichel Mourad
Department of Surgery, Surgery and Abdominal Transplantation Division, Cliniques Universitaires, St Luc, Universite Catholique de Louvain, Hippocrate Ave, 10 1200 Brussels, Belgium
Am J Surg 202:168-74. 2011..The Harmonic Focus is the last ultrasonic device designed for thyroid surgery. The aim is to assess its efficacy and safety compared with traditional dissection in a prospective randomized trial of total thyroidectomy procedures...
- The utility of serum PTH assessment 24 hours after total thyroidectomyPaolo Del Rio
General Surgery and Organ Transplantation Clinic, University of Parma, Italy
Otolaryngol Head Neck Surg 132:584-6. 2005b>Hypocalcemia is the most frequent complication following total thyroidectomy. This prospective study examines the predictive value of parathyroid hormone (PTH) levels measured 24 hours after surgery.
- Hypocalcemia complicating near-total thyroidectomy in patients with coexisting lipid malabsorption due to biliopancreatic diversionMelania Manco
Department of Internal Medicine, CNR Centro di Fisiopatologia dello Shock, Catholic University, School of Medicine, Rome, Italy
Obes Surg 14:1429-34. 2004Patients who have undergone biliopancreatic diversion (BPD) show a high incidence of mild hypocalcemia, which may become symptomatic and life-treating after an extensive thyroid operation.
- [Case of pseudohypoparathyroidism type 1b diagnosed as having hypocalcemia]Sayomi Iida
Izumiotsu Municipal Hospital, Japan
Clin Calcium 15:689-93. 2005The patient (age 46; female) had hypocalcemia without characteristic physical findings of Albright hereditary osteodystrophy in July, 1998. She had no evidence of tetany...
- Hypocalcemia, hypovitaminosis d osteopathy, osteopenia, and secondary hyperparathyroidism 32 years after jejunoileal bypassDhiren M Haria
Division of Endocrinology, Fairview Hospital System and Cleveland Clinic Health System, Cleveland, Ohio 44111, USA
Endocr Pract 11:335-40. 2005....
- Severe hypocalcemia following total thyroidectomy after biliopancreatic diversionP Martin Rojas-Marcos
Department of Endocrinology and Nutrition, Hospital Clinico Universitario San Carlos, Madrid, Spain
Obes Surg 15:431-4. 2005..patient who had undergone the biliopancreatic diversion of Larrad, and presented clinical symptoms of severe hypocalcemia and tetany after total thyroidectomy. Very high doses of i.v...
- Parathyroid hormone: a sensitive predictor of hypocalcemia following total thyroidectomyAvi Khafif
Department of Otolaryngology Head and Neck Surgery, Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Otolaryngol Head Neck Surg 134:907-10. 2006To investigate whether monitoring parathyroid hormone (PTH) could predict hypocalcemia following total thyroidectomy or other bilateral thyroid manipulations.
- Inadvertent parathyroidectomy during thyroid surgery: the incidence of a complication of thyroidectomyStavros Gourgiotis
First Surgical Department, Evangelismos General Hospital, Athens, Greece
Langenbecks Arch Surg 391:557-60. 2006..Incidental parathyroidectomy is a complication of thyroid surgery. The aim of this report is to explore the incidence, risk factors, and clinical relevance of inadvertent parathyroidectomy during thyroidectomy...
- Central compartment reoperation for recurrent/persistent differentiated thyroid cancer: patterns of recurrence, morbidity, and prediction of postoperative hypocalcemiaJong Lyel Roh
Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
Ann Surg Oncol 18:1312-8. 2011..compartment reoperation, but few prospective studies have assessed morbidities and factors predictive of hypocalcemia after reoperation...
- Pseudoaldosteronism with increased serum cortisol associated with pneumonia, hypouricemia, hypocalcemia, and hypophosphatemiaA Onishi
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan
Clin Nephrol 74:403-8. 2010..and exhibited elevated levels of serum cortisol and creatinine clearance (CCr) as well as hypouricemia, hypocalcemia, and hypophosphatemia...
- Predictability of hypocalcemia using early postoperative serum calcium levelsC Moore
Department of Otolaryngology, University of Western Ontario, St Joseph's Health Centre, London
J Otolaryngol 30:266-70. 2001..In this study, we wanted to determine whether early postoperative serum calcium levels could be used to predict hypocalcemia following operations of the thyroid or parathyroid glands...
- Risk factors for postthyroidectomy hypocalcemiaBassam Abboud
Department of General and Endocrine Surgery, Hotel Dieu de France Hospital, Beirut, Lebanon
J Am Coll Surg 195:456-61. 2002b>Hypocalcemia is a common complication of thyroidectomy. The aim of this study was to evaluate the incidence of hypocalcemia after thyroid operation and its relation to clinical, biologic, and surgical factors.
- Refractory hypocalcemia following near-total thyroidectomy in a patient with a prior Roux-en-Y gastric bypassSara M Pietras
Boston University School of Medicine, Boston Medical Center, Boston, MA 02118 2393, USA
Obes Surg 19:524-6. 2009..Thyroidectomy carries the risk of both immediate and long-term hypocalcemia. Here we describe a patient who underwent Roux-en-Y gastric bypass (RYGB) and subsequent near-total ..
- Is therapy with calcium and vitamin D and parathyroid autotransplantation useful in total thyroidectomy for preventing hypocalcemia?Bassam Abboud
Department of General Surgery, Hotel Dieu de France Hospital, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon
Head Neck 30:1148-54; discussion 1154-5. 2008Routine calcium and vitamin D administration and routine autotransplantation of parathyroid glands can prevent hypocalcemia after total thyroidectomy.
- Hypocalcemia, hypomagnesemia, and hypokalemia following hydrofluoric acid chemical injuryMaria Dalamaga
Department of Internal Medicine, NIMTS General Hospital, Athens, Greece
J Burn Care Res 29:541-3. 2008..This report describes the case of a 48-year-old man who developed hypocalcemia and hypomagnesemia accompanied by hypokalemia-an interesting finding-following a chemical injury with exposure ..
- Malignant infantile osteopetrosis initially presenting with neonatal hypocalcemia: case reportC J Chen
Department of Pediatrics, Tri Service General Hospital, National Defense Medical Center, No 325, Cheng Kung Rd, Sec 2, Neihu 114, Taipei, Taiwan
Ann Hematol 82:64-7. 2003..We describe the case of a 23-day-old boy in whom neonatal hypocalcemia was present initially after birth...
- High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout miceMatthew J Rowling
Department of Biological Sciences, University of Notre Dame, Notre Dame, IN 46556, USA
J Nutr 137:2608-15. 2007..The 1K diet impaired growth and caused hypocalcemia in KO mice; the 10K and 20K diets were as effective as the high Ca rescue diet in preventing these outcomes...
- Parathyroid risk in total thyroidectomy for bilateral, benign, multinodular goitre: report of 351 surgical casesC Page
Department of Anatomy, University Medical School of Amiens University of Picardie Jules Verne, Amiens, France
J Laryngol Otol 121:237-41. 2007....
- Parathyroid hormone fragments inhibit active hormone and hypocalcemia-induced 1,25(OH)2D synthesisM Usatii
Centre de Recherche, Centre Hospitalier de l Université de Montréal Hôpital Saint Luc, Montreal, Quebec, Canada
Kidney Int 72:1330-5. 2007..The C-terminal fragments did not influence either basal or rat 1-34- or 1-84-induced CYP27B1 mRNA levels, suggesting that their inhibitory effects on 1,25(OH)(2)D synthesis appears to be post-transcriptional...
- Transplant recipients on the edge of the hypocalcemia abyssPaul Lee
Department of Endocrinology, St Vincent s Hospital, New South Wales, Australia
J Heart Lung Transplant 28:93-5. 2009Hypovitaminosis D is a risk factor for transplant-related osteoporosis. Its contribution to severe hypocalcemia in transplant recipients is less well recognized...
- Disruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemiaVladimir Chubanov
Institute for Pharmacology and Toxicology, Philipps University Marburg, 35033 Marburg, Germany
Proc Natl Acad Sci U S A 101:2894-9. 2004..Together, our data suggest an important contribution of TRPM6/TRPM7 heterooligomerization for the biological role of TRPM6 in epithelial magnesium absorption...
- Hypocalcemia and osteopathy in mice with kidney-specific megalin gene defectJörg R Leheste
Max Delbrueck Center for Molecular Medicine, Berlin, Germany
FASEB J 17:247-9. 2003..However, lack of receptor expression in the kidney results in plasma vitamin D deficiency, in hypocalcemia and in severe bone disease, characterized by a decrease in bone mineral content, an increase in osteoid ..
- Functional characterization of a calcium-sensing receptor mutation in severe autosomal dominant hypocalcemia with a Bartter-like syndromeRosa Vargas-Poussou
INSERM U423, Department of Physiology, Universite Rene Descartes, Hopital Necker Enfants Malades, Paris, France
J Am Soc Nephrol 13:2259-66. 2002..However, in patients with autosomal dominant hypocalcemia (ADH), caused by CaSR gain-of-function mutations, a defect in tubular NaCl reabsorption with renal loss of NaCl ..
- Incidence of inadvertent parathyroid removal during thyroidectomyDerrick T Lin
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Laryngoscope 112:608-11. 2002..To assess the incidence of unintentional parathyroid removal during routine thyroidectomy and to identify factors that might predict patients at high risk...
- Risks and consequences of incidental parathyroidectomy during thyroid resectionRebecca S Sippel
Department of Surgery, University of Wisconsin, Madison, Wisconsin 53792, USA
ANZ J Surg 77:33-6. 2007..Inadvertent removal of the parathyroid glands during elective thyroid surgery occurs more frequently in certain high-risk patients and can lead to symptomatic hypocalcaemia...
- Vitamin D3 deficiency is associated with late-onset hypocalcemia after minimally invasive parathyroidectomy in a vitamin D borderline areaBrian Hung Hin Lang
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
World J Surg 34:1350-5. 2010..We aimed to examine the clinicopathologic features and short-term outcomes of vitamin D(3)-deficient patients after minimally invasive parathyroidectomy (MIP)...
- A safe and cost-effective short hospital stay protocol to identify patients at low risk for the development of significant hypocalcemia after total thyroidectomyZayna S Nahas
Department of Otolaryngology Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Laryngoscope 116:906-10. 2006..serum calcium levels early after total thyroidectomy can be used to develop an algorithm that identifies patients who are unlikely to develop significant hypocalcemia and can be safely discharged within 24 hours after surgery.
- Severe hypocalcemia following bisphosphonate treatment in a patient with Paget's disease of boneHeather E Whitson
GRECC, VA Medical Center, Durham, NC 27710, USA
Bone 39:954-8. 2006..Clinically significant hypocalcemia has not been reported in patients with Paget's disease of bone and normal parathyroid function treated with an ..
- Comparison of different thyroidectomy techniques for benign thyroid diseaseAyhan Koyuncu
Department of General Surgery, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
Endocr J 50:723-7. 2003..If individual factors and patient's preference are not in favor of lifelong L-thyroxin supplementation, however, DP may be carried out for benign thyroidal diseases instead of BST...
- Autosomal dominant hypocalcaemia caused by a Ca(2+)-sensing receptor gene mutationM R Pollak
Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02115
Nat Genet 8:303-7. 1994..We conclude that this extracellular domain mutation increases the receptor's activity at low Ca2+ concentrations, causing hypocalcaemia in patients heterozygous for such a mutation...
- Randomized study on oral administration of calcitriol to prevent symptomatic hypocalcemia after total thyroidectomyFrancesco Tartaglia
Department of Surgical Sciences, University La Sapienza, Rome, Italy
Am J Surg 190:424-9. 2005Symptomatic hypocalcemia remains the main postoperative complication after total thyroidectomy...
- Hypocalcemia: a pervasive metabolic abnormality in the critically illJ R Zivin
Department of Medicine, University of Washington, USA
Am J Kidney Dis 37:689-98. 2001b>Hypocalcemia has been reported in critically ill patients, most commonly in association with sepsis syndrome. However, the severity and incidence of hypocalcemia in nonseptic but critically ill patients has not been well defined...
- Management of the side-effects of intravenous bisphosphonates: targeting the serum parathyroid hormone elevationA Berruti
Ann Oncol 17:1854-5. 2006
- Perioperative parathyroid hormone levels in thyroid surgeryBobak A Ghaheri
Department of Otolaryngology Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
Laryngoscope 116:518-21. 2006Perioperative hypocalcemia from temporary parathyroid gland dysfunction is common after thyroid surgery. No reliable cutoff values for parathyroid hormone (PTH) and the subsequent possibility of developing hypocalcemia exist...
- Identification of patients at low risk for thyroidectomy-related hypocalcemia by intraoperative quick PTHFrancesco Di Fabio
Cattedra di Chirurgia Generale, University of Brescia School of Medicine, Brescia, Italy
World J Surg 30:1428-33. 2006..The aim of the study was to identify patients at risk of developing thyroidectomy-related hypocalcemia and symptoms by means of the intraoperative quick parathyroid hormone (PTH) assay.
- Hypomagnesemia with secondary hypocalcemia is caused by mutations in TRPM6, a new member of the TRPM gene familyKarl P Schlingmann
Department of Pediatrics, Philipps University of Marburg, Deutschhausstrasse 12, D 35037 Marburg, Germany
Nat Genet 31:166-70. 2002..mutations in TRPM6 (also known as CHAK2), encoding TRPM6, in autosomal-recessive hypomagnesemia with secondary hypocalcemia (HSH, OMIM 602014), previously mapped to chromosome 9q22 (ref. 3)...
- Di-George syndrome presenting with hypocalcaemia in adulthood: two case reports and a reviewP S Kar
Academic Department of Diabetes and Endocrinology, Queen Alexandra Hospital, Portsmouth PO6 3LY, UK
J Clin Pathol 58:655-7. 2005..These two patients show that Di-George syndrome can present in adulthood with hypocalcaemia. This is an important observation because the condition has profound implications for health and family planning...
- Hypocalcemia in trauma: frequent but frequently undetected and underestimatedDonat R Spahn
Crit Care Med 33:2124-5. 2005
- Low parathyroid hormone levels after thyroid surgery: a feasible predictor of hypocalcemiaPia Lindblom
Department of Surgery, Lund University Hospital, Lund, Sweden
Surgery 131:515-20. 2002Selecting patients with a low risk of hypocalcemia is mandatory if patients are to be discharged on the first day after bilateral thyroidectomy. This study investigated the predictive value of intraoperative parathyroid hormone (PTH).
- Genetics of endocrine and metabolic disorders: parathyroidR V Thakker
May Professor of Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Botnar Research Centre, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK
Rev Endocr Metab Disord 5:37-51. 2004
- Activating mutations of the calcium-sensing receptor: management of hypocalcemiaA Lienhardt
Service de Pediatrie, Centre Hospitalier Universitaire, 87042 Limoges, France
J Clin Endocrinol Metab 86:5313-23. 2001Activating mutations of the calcium-sensing receptor (CaR) can cause isolated hypoparathyroidism. Treatment of hypocalcemia in these patients remains to be optimized, because the use of 1-hydroxylated vitamin D3 derivatives can cause ..
- Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary hypocalcemiaKarl P Schlingmann
University Children s Hospital Marburg, Deutschhausstrasse 12, 35037 Marburg, Germany
J Am Soc Nephrol 16:3061-9. 2005Primary hypomagnesemia with secondary hypocalcemia is a rare autosomal recessive disorder characterized by profound hypomagnesemia associated with hypocalcemia...
- Post-parathyroidectomy hypocalcemia: incidence, risk factors, and managementElizabeth A Mittendorf
Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Am Surg 70:114-9; discussion 119-20. 2004The purpose of this study was to evaluate the incidence and severity of hypocalcemia after parathyroidectomy and delineate its risk factors. Data was retrieved from a prospective database...
- Spurious hypocalcemia after gadodiamide administrationSandra F Williams
Division of Endocrinology, Mayo Clinic College of Medicine, Jacksonville, FL 32224, USA
Mayo Clin Proc 80:1655-7. 2005Severe hypocalcemia may require prompt intervention to avoid life-threatening consequences...
- Preconditions of hemostasis in trauma: a review. The influence of acidosis, hypocalcemia, anemia, and hypothermia on functional hemostasis in traumaHeiko Lier
Department of Anaesthesiology and Intensive Care Medicine, University of Cologne, Cologne, Germany
J Trauma 65:951-60. 2008Beside the often discussed topics of consumption and dilution coagulopathy, additional perioperative impairments of coagulation are caused by acidosis, hypocalcemia, anemia, hypothermia, and combinations.
- MOLECULAR DEFINITION OF PSEUDOHYPOPARATHYROIDISMHARALD JUEPPNER; Fiscal Year: 2001..PHP-Ia is characterized by PTH-resistant hypocalcemia and hyperphosphatemia, impaired function of several other endocrine systems, and a variety of developmental/..
- SYNDROMIC CARDIAC OUTFLOW TRACT DEFECTSDeepak Srivastava; Fiscal Year: 2002..occur as part of DiGeorge/CATCH-22 (cardiac defects, abnormal facies, thymic hypoplasia, cleft palate, and hypocalcemia associated with chromosome 22 microdeletion) syndrome...
- The Effect of PTHrP During LactationJohn Wysolmerski; Fiscal Year: 2007..This feedback loop may be particularly important to protect the mother from hypocalcemia when dietary calcium supplies are limiting...
- Treatment of Hypoparathyroidism with Parathyroid HormoneJohn P Bilezikian; Fiscal Year: 2010..Without PTH, patients have abnormal calcium homeostasis characterized by hypocalcemia and high urinary calcium excretion. The current mainstay of therapy is calcium and vitamin D...
- The Effect of PTHrP During LactationJohn J Wysolmerski; Fiscal Year: 2010..This feedback loop may be particularly important to protect the mother from hypocalcemia when dietary calcium supplies are limiting...
- VITAMIN D RECEPTOR ABLATION: DIRECT AND INDIRECT CONSEQUENCESMarie Demay; Fiscal Year: 2007..VDR knockout mice develop hypocalcemia and secondary hyperparathyroidism which, in turn, leads to hypophosphatemia...
- Vitamin D: A Negative Regulator of Renin ExpressionYan Chun Li; Fiscal Year: 2003..We demonstrated that the renin up-regulation is independent of the hypocalcemia associated with vitamin D receptor (VDR) ablation in VDR knockout (VDRKO) mice, but whether the secondary ..
- BONE PROPERTIES IN HYPOPARATHYROIDISM: EFFECTS OF PTHJohn P Bilezikian; Fiscal Year: 2010..leads to a reduction in the serum calcium concentration that can be asymptomatic or associated with symptoms of hypocalcemia. PTH deficiency also leads to major abnormalities in biochemical, densitometric, histomorphometric, ..
- Renal Osteodystrophy and Vascular CalcificationKeith Hruska; Fiscal Year: 2009..Until now, renal osteodystrophy was thought to result from secondary hyperparathyroidism produced by hypocalcemia due to hyperphosphatemia and calcitriol deficiency...
- Renal Osteodystrophy and Vascular CalcificationKeith A Hruska; Fiscal Year: 2010..Until now, renal osteodystrophy was thought to result from secondary hyperparathyroidism produced by hypocalcemia due to hyperphosphatemia and calcitriol deficiency...
- Renal Osteodystrophy and Vascular CalcificationKeith Hruska; Fiscal Year: 2007..Until now, renal osteodystrophy was thought to result from secondary hyperparathyroidism produced by hypocalcemia due to hyperphosphatemia and calcitriol deficiency...
- CA2+-RECEPTOR: IMMUNE MODULATION IN VIVO AND IN VITROEdward M Brown; Fiscal Year: 2007..The former is termed autosomal dominant hypocalcemia (ADH) and the latter familial hypocalciuric hypercalcemia (FHH)...
- MOLECULAR DEFINITION OF PSEUDOHYPOPARATHYROIDISMHARALD JUEPPNER; Fiscal Year: 2007Pseudohypoparathyroidism type Ib (PHP-lb) is characterized by hypocalcemia and hyperphosphatemia due to renal resistance towards parathyroid hormone (PTH). Autosomal dominant PHP-lb (AD-PHP-lb) was mapped to chromosome 20q13...
- FUNCTION OF THE CALCIUM SENSING RECEPTOR IN THE BREASTJohn Wysolmerski; Fiscal Year: 2007..delivery to the mammary gland falls in order to increase maternal bone resorption, protect against maternal hypocalcemia and restore the supply of calcium for milk production...
- FUNCTION OF THE CALCIUM SENSING RECEPTOR IN THE BREASTJohn Wysolmerski; Fiscal Year: 2009..delivery to the mammary gland falls in order to increase maternal bone resorption, protect against maternal hypocalcemia and restore the supply of calcium for milk production...
- Vitamin D Control of TGFa/EFG Receptor Growth SignalingAdriana Dusso; Fiscal Year: 2006..Hyperplasia of PTH-producing cells is a major cause of high serum PTH levels. While it is known that hypocalcemia, hyperphosphatemia, and vitamin D deficiency promote parathyroid (PT) hyperplasia in renal failure, the ..
- Bone Quality in Hypoparathyroidism: Effects of PTHMishaela Rubin; Fiscal Year: 2007..Along with abnormal calcium homeostasis, namely hypocalcemia and hyperphosphatemia, parathyroid hormone deficiency leads to reduced skeletal turnover...
- KENNY CAFFY SYNDROME: BONE SCLEROSIS AND HYPOCALCEMIAGeorge Diaz; Fiscal Year: 2003..The principal manifestations KCS are short stature and hypocalcemia, but significant additional manifestations include eye abnormalities, developmental delay and immune deficits...